CN109364006A - A kind of acne-removing composition, Essence and preparation method thereof - Google Patents
A kind of acne-removing composition, Essence and preparation method thereof Download PDFInfo
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- CN109364006A CN109364006A CN201811470210.1A CN201811470210A CN109364006A CN 109364006 A CN109364006 A CN 109364006A CN 201811470210 A CN201811470210 A CN 201811470210A CN 109364006 A CN109364006 A CN 109364006A
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- polyquaternium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Abstract
The invention discloses a kind of acne-removing compositions, contain the following parts by weight: 0.25~2 part of chitosan, 0.0005~0.002 part of polyquaternium -73 and 1~5 part of aloe extract.Acne-removing composition of the present invention selects chitosan, polyquaternium -73 and aloe extract to carry out rational allocation; synergistic anti-acne effect can be played; in acne-removing composition; bacterium, Propiobacterium can be killed and be inhibited to polyquaternium -73; aloe extract can play repairing effect; chitosan forms protective film on acne surface simultaneously; it can prevent microorganism attachment, invasion; it can promote wound healing; be conducive to accelerate the reparation of acne; even if therefore polyquaternium -73 still has the effect of very strong antibacterial, anti-inflammatory, anti-acne under seldom additive amount.The invention also discloses a kind of anti-acne skin care item.The invention also discloses a kind of anti-acne essences.The invention also discloses a kind of preparation methods of anti-acne essence.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of acne-removing composition, Essence and preparation method thereof.
Background technique
Whelk is the chronic dermatosis occurred in pilosebaceous follicle, and the factor of generation is varied.Wherein lead to the youth
The reason of acne includes internal cause and external cause, and internal cause: endocrine function imbalance, 3male hormone secretion increase or increase relatively, stimulate skin
Adipose gland hyperplasia, secretion oil quantity increase；External cause: psychoneural factor；Dietary factor；Stool, sleep etc. personal behavior because
Element；The predisposing factors such as cigarette, wine, drug factors, cosmetics and skin nursing factor etc..Along with the improvement of living standards,
The food and high pressure for being no lack of pungent, the greasy greasiness of some raw foods in the diet daily schedule irregular under the influence of living, all can
Opportunity is left for small pox.But most direct reason is exactly clogging of pores.After clogging of pores, the grease row inside hair follicle is not
Out, cumulative just to form small small pox one by one.
There are many anti-acne essence in the market, but its component is more, such as disclosure " a kind of anti-acne reparation Essence liquid "
(CN107412097A) by oligopeptides, trehalose, beta glucan, quaternary ammonium salt -73, o- cymene -5- alcohol, hydroxy phenylpropionyl amine benzene first
The grouping of the groups such as acid, aloe extract, allantoin, glycerol, butanediol, xanthan gum, parahydroxyacet-ophenone, carbomer, triethanolamine
At recipe ingredient is more, such as disclosure " a kind of mild oil control and acne removal Essence " (CN107789308A), component are as follows:
Water, glycerol, propylene glycol, EDETATE SODIUM, xanthan gum, ammonium acryloyl taurate/VP copolymer, allantoin, panthenol, tree peony
Root extract, parahydroxyacet-ophenone, Phenoxyethanol, Sensiva SC50, sodium benzoate, citric acid, 5 alcohol of o cymene, cork tree tree
Bark extract, butanediol, 10 hydroxydecanoic acids, hamamelis extract, lactic acid bacteria/mung bean seed extract tunning filtrate,
Quaternary ammonium salt -73,40 rilanit special of PEG, essence.Existing product for resolving poxes, ingredient is more, and technique is more complex, at high cost.
Summary of the invention
A kind of acne-removing composition, Essence are provided it is an object of the invention to overcome in place of the shortcomings of the prior art
And preparation method thereof.
To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of acne-removing composition includes following parts by weight
Component: 0.25~2 part of chitosan, 0.0005~0.002 part of polyquaternium -73 and 1~5 part of aloe extract.
The present invention provides a kind of anti-acne essences, have very strong antibacterial, anti-inflammatory, anti-acne effect.
Chitosan has very strong antimicrbial power, can form layer protecting film on small pox surface, prevents microorganism attachment, enters
It invades, cell activation can be promoted, promote granulation growth, to accelerate wound healing.Polyquaternium -73 is a kind of new high-efficiency anti-acne
Bacterium, staphylococcus, Escherichia coli etc. are had extremely strong killing energy by anti-inflammatory agent, acne, acne inhibitor with antibacterial activity
Power.Aloe extract has very strong moisturizing performance, can inhibit inflammatory factor, improves skin health degree, and can help skin
It repairs.
Acne-removing composition of the present invention selects chitosan, polyquaternium -73 and aloe extract to carry out rational allocation, energy
Synergistic anti-acne effect is played, in acne-removing composition, bacterium, Propiobacterium, reed can be killed and be inhibited to polyquaternium -73
Luxuriant growth extract can play repairing effect, while chitosan forms protective film on acne surface, can prevent microorganism attachment, invasion,
It can promote wound healing, be conducive to the reparation for accelerating acne, therefore the use of chitosan can greatly reduce polyquaternium -73
Dosage, polyquaternium -73 is expensive, it is possible thereby to reduce cost, even if polyquaternium -73 under seldom additive amount,
Still have the effect of very strong antibacterial, anti-inflammatory, anti-acne.
As the preferred embodiment of acne-removing composition of the present invention, the acne-removing composition includes following parts by weight
Component: 0.5~2 part of chitosan, 0.001~0.002 part of polyquaternium -73 and 3~5 parts of aloe extract.
As the preferred embodiment of acne-removing composition of the present invention, the acne-removing composition includes following parts by weight
Component: 1.5 parts of chitosan, 0.0015 part of polyquaternium -73 and 4 parts of aloe extract.
The object of the invention is also to provide a kind of anti-acne skin care item, the anti-acne skin care item are combined comprising above-mentioned anti-acne
Object.The anti-acne skin care item can add different auxiliary materials in above-mentioned acne-removing composition, be prepared into mildy wash, facial mask, essence
The different dosage forms skin care item such as liquid, essence cream, toner, moisturizer.
The object of the invention is also to provide a kind of anti-acne essence, the anti-acne essence is combined comprising above-mentioned anti-acne
Object.
As the preferred embodiment of anti-acne essence of the present invention, the anti-acne essence is contained by following weight percent
The group of amount is grouped as: chitosan 0.25~2%, polyquaternium -73 0.0005~0.002%, aloe extract 1~5%, small
Pyrenomycetes glue 0.6~1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2%~1% and surplus water.
The ingredient of anti-acne essence of the present invention is simple, can polyquaternium -73 additive amount within 0.0002%, can have
Extraordinary anti-acne effect.
As the preferred embodiment of anti-acne essence of the present invention, the anti-acne essence is contained by following weight percent
The group of amount is grouped as: chitosan 0.5~2%, polyquaternium -73 0.001~0.002%, aloe extract 1~5%, small nut
Bacterium glue 0.6~1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2~1% and surplus water.Upper
It states under proportion, chitosan, polyquaternium -73 and aloe extract can preferably cooperate, and have more preferably anti-acne effect and moisturizing
Effect.
As the preferred embodiment of anti-acne essence of the present invention, the anti-acne essence is contained by following weight percent
The group of amount is grouped as: chitosan 1.5%, polyquaternium -73 0.0015%, aloe extract 3~5%, Scleroglucan 0.6~
1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2~1% and surplus water.
As the preferred embodiment of anti-acne essence of the present invention, the anti-acne essence is contained by following weight percent
The group of amount is grouped as: chitosan 1.5%, polyquaternium -73 0.0015%, aloe extract 4%, Scleroglucan 0.8%, third
Glycol 3%, butanediol 2%, hexylene glycol 0.4% and surplus water.Using above-mentioned formula anti-acne essence anti-acne effect most
It is good, the evaluation highest of user.
The object of the invention is also to provide a kind of preparation method of anti-acne essence, the systems of the anti-acne essence
Preparation Method the following steps are included:
(1), chitosan, Scleroglucan and propylene glycol are dissolved with water；
(2), 78~82 DEG C are heated to, mixing speed is 10~20r/min, stirs 15~25min；
(3), 43~48 DEG C are cooled to, the polyquaternium -73 of butanediol dissolution is added, mixing speed is 15~25r/min,
Time is 3~8 minutes；
(4), hexylene glycol and aloe extract is added, stirs to get the anti-acne essence.
The preparation process of above-mentioned anti-acne essence is simple, is suitable for batch production.
The beneficial effects of the present invention are: the present invention provides a kind of acne-removing composition, acne-removing composition of the present invention
It selects chitosan, polyquaternium -73 and aloe extract to carry out rational allocation, synergistic anti-acne effect can be played, dispelled
In acne composition, bacterium, Propiobacterium can be killed and be inhibited to polyquaternium -73, and aloe extract can play repairing effect, simultaneously
Chitosan forms protective film on acne surface, can prevent microorganism attachment, invasion, can promote wound healing, is conducive to accelerate Cuo
The reparation of sore, therefore the use of chitosan can greatly reduce the dosage of polyquaternium -73, can reduce cost, even if poly-
Quaternary ammonium salt -73 still has the effect of very strong antibacterial, anti-inflammatory, anti-acne under seldom additive amount.The present invention also provides one kind
Anti-acne skin care item.The present invention also provides a kind of anti-acne essences.Anti-acne essence ingredient of the present invention is simple, can be in poly- season
The additive amount of ammonium salt -73 can have extraordinary anti-acne effect within 0.0002%.The present invention also provides a kind of anti-acnes
The preparation method of Essence.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1~15
Embodiment 1~15 is the embodiment of anti-acne essence of the present invention, the anti-acne essence of embodiment 1~15
Formula is shown in Table 1.
The preparation method of the anti-acne essence of embodiment 1~15 the following steps are included:
(1), chitosan, Scleroglucan and propylene glycol are dissolved with water；
(2), 80 DEG C, mixing speed 15r/min are heated to, 20min is stirred；
(3), 45 DEG C are cooled to, the polyquaternium -73 of butanediol dissolution, mixing speed 20r/min, time 5 is added
Minute；
(4), hexylene glycol and aloe extract is added, the speed stirring 5min of 30r/min is to get the anti-acne essence.
Comparative example 1~3
The formula of the Essence of comparative example 1~3 is shown in Table 1, and the preparation method is the same as that of Example 1 for the Essence~and 15.
The formula of the anti-acne essence of 1 embodiment of table 1~15
Embodiment 16
To verify anti-acne essence of the present invention in the effect of antibiosis, " disposably make referring to GB15979-2002
With amenities sanitary standard " appendix C 4 " stripping property resists (suppression) bacterium product bacteriostasis property test method " is to the embodiment of the present invention 1
~15 and the anti-acne essence of comparative example 1~3 carry out bacteriostasis property measurement: (1) preparation of bacteria suspension: take propionibacterium acnes
(ATCC6919) culture is washed down with 0.03mol/L phosphate buffer for 24 hours, is made 104~106CFU/mL bacteria suspension；(2) divide
It does not take by test agent 1g, above-mentioned bacteria suspension 0.1mL even spread mixing is added, starts timing, 9mL is added after 20min
0.03mol/L phosphate buffer mixes well, and after doing appropriate dilution, takes wherein 3 dilutions, 1mL is taken to be placed in two respectively
In parallel plate, adds corresponding culture medium and cultivated 24 hours under 36 ± 1 DEG C of anaerobic conditions, make bacterium colony counting.The above test
It is repeated 3 times, is averaged, blank control group is set.
The calculation formula of bacteriostasis rate are as follows: X=(A-B)/A × 100%, wherein X is bacteriostasis rate, and A is that control sample averagely returns
Bacterium colony is received, B is that test specimen averagely recycles bacterium colony.
Acne-removing evaluation criterion are as follows: (1), bacteriostasis rate >=90% be it is effective；(2), it is effective that bacteriostasis rate, which is 50~90%,；
(3), bacteriostasis rate < 50% is invalid.
The evaluation of the bacteriostasis efficacy of embodiment 1~15 and the anti-acne essence of comparative example 1~3 is shown in Table 2.
The evaluation of the bacteriostasis efficacy of 2 embodiment 1~15 of table and the anti-acne essence of comparative example 1~3
| Group | Bacteriostasis rate (%) | Acne-removing evaluation |
| Embodiment 1 | 94.5 | It is effective |
| Embodiment 2 | 91.0 | It is effective |
| Embodiment 3 | 89.1 | Effectively |
| Embodiment 4 | 93.1 | It is effective |
| Embodiment 5 | 91.5 | It is effective |
| Embodiment 6 | 93.0 | It is effective |
| Embodiment 7 | 92.5 | It is effective |
| Embodiment 8 | 80.6 | Effectively |
| Embodiment 9 | 89.3 | Effectively |
| Embodiment 10 | 95.5 | It is effective |
| Embodiment 11 | 95.7 | It is effective |
| Embodiment 12 | 83.0 | Effectively |
| Embodiment 13 | 91.6 | It is effective |
| Embodiment 14 | 94.9 | It is effective |
| Embodiment 15 | 95.3 | It is effective |
| Comparative example 1 | 45.9 | In vain |
| Comparative example 2 | 70.8 | Effectively |
| Comparative example 3 | 91.1 | It is effective |
Can be seen that the anti-acne essence of embodiment 1~15 from the data of table 1 has sterilization suppression to propionibacterium acnes
Bacterium effect, acne-removing are evaluated as effective or effective.From embodiment 1,4~7, comparative example 3 as can be seen that the anti-acne essence
Liquid has preferable bactericidal and bacteriostatic effect, it may be possible to which the film-formation result of chitosan is to bactericidal under above-mentioned antibacterial test condition
Influential effect is little, also illustrates that chitosan itself is weaker to the bactericidal effect of propionibacterium acnes.From embodiment 1,8~11,
The result that comparative example 1,3 can be seen that can be seen that the increase with -73 additive amount of polyquaternium, and bacteriostasis rate increases, and illustrate poly-
Quaternary ammonium salt -73 has certain bactericidal effect, and -73 additive amount of polyquaternium is at 0.001~0.002%, that is, can reach compared with
Good fungistatic effect is unobvious, and in the additive amount for increasing polyquaternium -73, fungistatic effect increase is unobvious, but it is produced
Increased costs.It can be seen that the increase of the additive amount with aloe extract from embodiment 1,12~15, the result of comparative example 2,
Bacteriostasis rate increases, and illustrates that aloe extract has certain bactericidal effect, and adding when aloe extract to propionibacterium acnes
When dosage is greater than 4%, with the increase of the additive amount of aloe extract, fungistatic effect increase is unobvious, therefore preferred aloe
The additive amount of extract is 3~5%, more preferably 4%.
Embodiment 17
Clinical test is carried out to Examples 1 to 7 and the anti-acne essence of comparative example 1~3, specific as follows:
Number: 120 people (male 65, women 55) are divided into 12 groups, every group of 10 people, face has acne
Time: 21 days
Position: face
Sample: Examples 1 to 7 and the anti-acne essence of comparative example 1~3
Evaluation: (photo is not shown) is evaluated and is taken pictures in progress according to GAGS point-score:
GAGS point-score is Doshi etc. the 1997 acne comprehensive classification system Global Acne Grading proposed
System (GAGS) is a kind of scoring method, has the characteristics that accurate, consistency is strong, quick and overall assessment effect is good.Specifically
Are as follows: according to the density of pilosebaceous unit, distribution and approximate area, acne predilection site is divided into 6 areas: Ith area, forehead, II
Area: right cheek, IIIth area: left cheek, IVth area: nose, V area Xia Ke of area, VIth area: chest and upper back.Ith area, IIth area, III area's factor score value
It is 2, IVth area, V area's factor score value are 1, and VI area's factor score value is 3, and each region skin lesion score value is that (principle is local most serious
Skin lesion determine the score value in the area): 0=is without skin lesion；1 >=1 acne；2 >=1 papules；3 >=1 running sores；4 >=1 tubercles.
Area's total score=factor score value × skin lesion score value, the sum of variant dermatotome total score are comprehensive scores.
Evaluation result is shown in Table 3.
The GAGS of 3 Examples 1 to 7 of table and the anti-acne essence of comparative example 1~3 score evaluation result
| Group | Before use | 3 days | 7 days | 14 days | 21 days |
| Embodiment 1 | 18.0 | 13.5* | 10.5** | 8.4** | 6.6** |
| Embodiment 2 | 18.4 | 15.5* | 13.5** | 11.5** | 10.9** |
| Embodiment 3 | 18.5 | 16.2* | 13.3** | 11.2** | 10.1** |
| Embodiment 4 | 18.8 | 16.3* | 14.0** | 13.0** | 11.8** |
| Embodiment 5 | 18.6 | 15.3* | 12.9** | 10.1** | 8.4** |
| Embodiment 6 | 18.2 | 13.6* | 11.0** | 9.0** | 6.5** |
| Embodiment 7 | 18.5 | 15.7* | 12.7* | 9.5** | 6.8** |
| Comparative example 1 | 18.5 | 17.0 | 16.2* | 15.6** | 14.5** |
| Comparative example 2 | 18.2 | 16.8 | 15.8* | 14.2** | 12.0** |
| Comparative example 3 | 18.6 | 15.8 | 14.5* | 12.8** | 10.3** |
* P < 0.05VS is before use, before * * P < 0.01VS use
From table 3 it can be seen that with use it is preceding compared with, acne score value is obvious after anti-acne essence 3 days described in Examples 1 to 7
It reduces (P < 0.05), is significantly reduced when using 7,14 and 21 days, and statistically significant (P < 0.01).It can from table
Out, compared with Example 1, the comprehensive scores of embodiment 4~7, comparative example 3 after using 21 days are higher, illustrate that chitosan can have
The reparation for helping acne, with the increase of chitosan content, anti-acne effect has certain increase, but when additive amount is greater than
When 1.5%, the increase of anti-acne effect improvement is unobvious, illustrates that chitosan can give full play to it when additive amount is 0.5~2%
When anti-acne effect, especially additive amount are 1.5%, the utilization efficiency highest of chitosan.From Examples 1 to 3 and comparative example 1~3
Comparison can be seen that anti-acne effect when being used in conjunction with using chitosan, polyquaternium -73 and aloe extract better than only making
With one such anti-acne effect.Illustrate that chitosan, polyquaternium -73 and aloe extract can act on skin, it is common to send out
Wave anti-acne effect or auxiliary anti-acne effect.
Embodiment 18
In order to verify the anti-acne effect of anti-acne essence of the present invention, anti-acne essence described in embodiment 1 is carried out following real
It tests:
Choose 100 light, the long acne volunteer of moderate face: wherein male 50, female 50, the age 16~40 years old.
Application method: taking few drops of this product, and a general 0.05ml of drop has been applied to hair acne trend or has sent out acne affected part, often
Its spot printing 3~4 times, 7 days as one therapeutic course.
Criterion of therapeutical effect:
It cures: 90% or more small pox recession,
It is effective: 60% or more small pox recession,
It is invalid: 50% or less small pox recession
As a result: in 100 long acne user, fully recovering 93, account for 93%；Effective 5, account for 5%；Invalid 2, account for 2%；Always
Effective percentage is 98.0%.During on probation, all try out does not occur the adverse reactions such as allergy per capita, illustrates anti-acne of the present invention
Essence has good acne-removing.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of acne-removing composition, which is characterized in that contain the following parts by weight: 0.25~2 part of chitosan, polyquaternary amine
0.0005~0.002 part and 1~5 part of aloe extract of salt -73.
2. acne-removing composition as described in claim 1, which is characterized in that the acne-removing composition includes the group of following parts by weight
Point: 0.5~2 part of chitosan, 0.001~0.002 part of polyquaternium -73 and 3~5 parts of aloe extract.
3. acne-removing composition as described in claim 1, which is characterized in that the acne-removing composition includes the group of following parts by weight
Point: 1.5 parts of chitosan, 0.0015 part of polyquaternium -73 and 4 parts of aloe extract.
4. a kind of anti-acne skin care item, which is characterized in that include acne-removing composition described in any one of claims 1 to 3.
5. a kind of anti-acne essence, which is characterized in that include acne-removing composition described in any one of claims 1 to 3.
6. anti-acne essence as claimed in claim 5, which is characterized in that the anti-acne essence is by following weight percentage
Group is grouped as: chitosan 0.25~2%, polyquaternium -73 0.0005~0.002%, aloe extract 1~5%, pyrenomycetes
Glue 0.6~1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2%~1% and surplus water.
7. anti-acne essence as claimed in claim 5, which is characterized in that the anti-acne essence is by following weight percentage
Group is grouped as: chitosan 0.5~2%, polyquaternium -73 0.001~0.002%, aloe extract 1~5%, Scleroglucan
0.6~1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2~1% and surplus water.
8. anti-acne essence as claimed in claim 5, which is characterized in that the anti-acne essence is by following weight percentage
Group is grouped as: chitosan 1.5%, polyquaternium -73 0.0015%, aloe extract 3~5%, Scleroglucan 0.6~
1.2%, propylene glycol 1.5~5%, butanediol 0.999~3%, hexylene glycol 0.2~1% and surplus water.
9. anti-acne essence as claimed in claim 5, which is characterized in that the anti-acne essence is by following weight percentage
Group is grouped as: chitosan 1.5%, polyquaternium -73 0.0015%, aloe extract 4%, Scleroglucan 0.8%, propylene glycol
3%, the water of butanediol 2%, hexylene glycol 0.4% and surplus.
10. a kind of preparation method of the anti-acne essence as described in any one of claim 5~9, which is characterized in that including following
Step:
(1), chitosan, Scleroglucan and propylene glycol are dissolved with water；
(2), 78~82 DEG C are heated to, mixing speed is 10~20r/min, stirs 15~25min；
(3), 43~48 DEG C are cooled to, the polyquaternium -73 of butanediol dissolution is added, mixing speed is 15~25r/min, time
It is 3~8 minutes；
(4), hexylene glycol and aloe extract is added, stirs to get the anti-acne essence.
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| CN201811470210.1A Pending CN109364006A (en) | 2018-12-03 | 2018-12-03 | A kind of acne-removing composition, Essence and preparation method thereof |
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| CN110787095A (en) * | 2019-12-14 | 2020-02-14 | 广州伊尔美生物科技有限公司 | Acne removing composition |
| CN112006956A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Acne-removing cream and preparation process thereof |
| CN112451552A (en) * | 2020-12-19 | 2021-03-09 | 江苏诺瓦立医疗用品有限公司 | Novel hydrocolloid acne patch for treating acne |
| CN113089151A (en) * | 2021-04-07 | 2021-07-09 | 罗莱生活科技股份有限公司 | Three-dimensional antibacterial yarn containing cotton fibers, preparation method of three-dimensional antibacterial yarn and towel product |
| CN113350255A (en) * | 2021-07-07 | 2021-09-07 | 广州天然国度生物科技有限公司 | Low-irritation antibacterial cosmetic and preparation method thereof |
| CN114469833A (en) * | 2022-03-30 | 2022-05-13 | 广州市白云莱茵化妆品厂 | Acne-removing additive containing plant extracts and skin care product |
| CN115737520A (en) * | 2022-12-16 | 2023-03-07 | 唤新肌生物科技(深圳)有限公司 | Oil-control acne-removing face-cleaning composition |
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| CN110787095A (en) * | 2019-12-14 | 2020-02-14 | 广州伊尔美生物科技有限公司 | Acne removing composition |
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| CN112006956A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Acne-removing cream and preparation process thereof |
| CN112451552A (en) * | 2020-12-19 | 2021-03-09 | 江苏诺瓦立医疗用品有限公司 | Novel hydrocolloid acne patch for treating acne |
| CN113089151A (en) * | 2021-04-07 | 2021-07-09 | 罗莱生活科技股份有限公司 | Three-dimensional antibacterial yarn containing cotton fibers, preparation method of three-dimensional antibacterial yarn and towel product |
| CN113089151B (en) * | 2021-04-07 | 2022-06-17 | 罗莱生活科技股份有限公司 | Three-dimensional antibacterial yarn containing cotton fibers, preparation method of three-dimensional antibacterial yarn and towel product |
| CN113350255A (en) * | 2021-07-07 | 2021-09-07 | 广州天然国度生物科技有限公司 | Low-irritation antibacterial cosmetic and preparation method thereof |
| CN114469833A (en) * | 2022-03-30 | 2022-05-13 | 广州市白云莱茵化妆品厂 | Acne-removing additive containing plant extracts and skin care product |
| CN115737520A (en) * | 2022-12-16 | 2023-03-07 | 唤新肌生物科技(深圳)有限公司 | Oil-control acne-removing face-cleaning composition |
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