CN110787095A - Acne removing composition - Google Patents

Acne removing composition Download PDF

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Publication number
CN110787095A
CN110787095A CN201911286748.1A CN201911286748A CN110787095A CN 110787095 A CN110787095 A CN 110787095A CN 201911286748 A CN201911286748 A CN 201911286748A CN 110787095 A CN110787095 A CN 110787095A
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acne
removing composition
skin
parts
extract
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CN110787095B (en
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朱院金
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Guangzhou Yiermei Biotechnology Co Ltd
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Guangzhou Yiermei Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention relates to an acne-removing composition, and provides an acne-removing composition aiming at the problem that residual marks of an acne-removing product are not effectively repaired after acne is removed, wherein the acne-removing composition comprises the following components in parts by mass: 11-24 parts of safflower extract; 12-27 parts of salvia miltiorrhiza root extract; 7-15 parts of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester; 8.05-18.15 parts of propylene glycol. A preparation method of an acne-removing composition comprises the steps of mixing and uniformly stirring all the components of the acne-removing composition according to the parts by mass to obtain the acne-removing composition. An application of an acne-removing composition is provided, wherein the acne-removing composition is added into skin care products. By compounding the safflower extract, the salvia miltiorrhiza extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol, the components can be mutually cooperated and mutually promoted, so that the repairing and conditioning of skin are facilitated, acne residual pockmarks are effectively removed, and meanwhile, moisture is locked, and the barrier function of the skin is maintained.

Description

Acne removing composition
Technical Field
The invention relates to the field of cosmetics, and particularly relates to an acne-removing composition.
Background
The acne is commonly known as acne, also called as pimple, pimple or comedo, is a chronic inflammatory skin disease of a pilosebaceous unit, mainly occurs in adolescents, after the acne enters the adolescent period, the level of androgen, particularly testosterone, in a human body is rapidly increased, the sebaceous gland development is promoted, a large amount of sebum is produced, meanwhile, abnormal keratinization of the pilosebaceous canal causes the canal blockage, sebum discharge obstacle, cutin plug, namely comedo, or polymorphic skin lesions such as papule, pustule, nodule and the like are formed.
The existing acne-removing product can achieve the effects of inhibiting bacteria and controlling oil in a short time for solving the problems of inflammation caused by excessive sebum secretion, follicular keratosis, pore blockage, infection of acne-related bacteria, grease degradation and the like. However, most acne removing products can only remove acnes on the skin surface, and the marks left by the acnes still remain and are not effectively repaired. Therefore, there is room for improvement.
Disclosure of Invention
Aiming at the defects in the prior art, the first purpose of the invention is to provide an acne-removing composition which has the advantages of enhancing skin repair and effectively removing residual acne marks.
The second purpose of the invention is to provide a preparation method of the acne-removing composition, which has the advantages of simple preparation and convenient operation.
The third purpose of the invention is to provide the application of the acne-removing composition, which has the advantage of wide application range.
In order to achieve the first object, the invention provides the following technical scheme:
the acne-removing composition comprises the following components in parts by mass:
11-24 parts of safflower extract;
12-27 parts of salvia miltiorrhiza root extract;
7-15 parts of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester;
8.05-18.15 parts of propylene glycol.
By adopting the technical scheme, the safflower extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol are compounded for use, so that the components are mutually cooperated and mutually promoted, the acne-removing composition can activate the activity of skin cells and promote the cell regeneration, the self-repair of the skin is promoted, the residual impression can be timely eliminated after acne is removed, simultaneously, the cooperation of the components can promote the keratinocytes and the lipids between the keratinocytes to form a firm structure, the flow of water inside and outside the cells and among the cells is limited, the water is supplemented and locked, and the important barrier function of the skin is maintained.
The invention is further configured to: the paint also comprises the following components in parts by mass:
18-30 parts of leonurus tenuifolius extract.
By adopting the technical scheme, the addition of the leonurus tenuifolius extract is beneficial to better promoting the mutual synergistic cooperation of the safflower extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol, so that the acne-removing composition further promotes the metabolism of skin cells, thereby accelerating the skin repair and more effectively eliminating the residual marks of acne.
The invention is further configured to: the paint also comprises the following components in parts by mass:
6-15 parts of saffron extract.
By adopting the technical scheme, the crocus sativus extract is added, so that the mutual synergistic cooperation of the crocus sativus extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol is favorably promoted, the water retention function of the acne-removing composition is better improved, and the water locking performance of the acne-removing composition is improved; meanwhile, the saffron extract can precipitate partial protein in the tissue to promote tissue shrinkage, inhibit excessive sebum secretion, be beneficial to better keeping skin fresh and promote skin antibiosis and antiphlogosis.
The invention is further configured to: the paint also comprises the following components in parts by mass:
0.15 part of polyquaternium-730.02.
By adopting the technical scheme, the polyquaternium-73 and the saffron extract are added to be matched with each other in a synergistic manner, so that the synergistic cooperation of the safflower extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and propylene glycol is favorably promoted, the skin can absorb the effective ingredients in the acne-removing composition more easily, the skin immunity is improved better, the skin repair is promoted, meanwhile, the long-acting water locking of the skin is favorably promoted, and the effect is better.
In order to achieve the second object, the invention provides the following technical scheme:
a preparation method of an acne-removing composition comprises the steps of mixing and uniformly stirring all the components of the acne-removing composition according to the parts by mass to obtain the acne-removing composition.
By adopting the technical scheme, the acne-removing composition can be prepared by uniformly mixing and stirring the components according to the mass part ratio, is simple and rapid to operate, is beneficial to saving the production and preparation time of the acne-removing composition and improves the production and preparation efficiency.
The invention is further configured to: the acne removing composition is uniformly mixed and stirred at normal temperature.
By adopting the technical scheme, the acne-removing composition is produced and prepared at normal temperature, the mixing condition is simple, the preparation process is convenient to control, and the error caused by improper operation in the mixing process is reduced.
In order to achieve the third object, the invention provides the following technical solutions:
an application of an acne-removing composition is to add the acne-removing composition into a skin care product.
By adopting the technical scheme, the acne-removing composition is added into the skin care product for use, so that the acne-removing effect of the skin care product is favorably improved, and meanwhile, the skin care product can enhance skin repair and restore the skin barrier function when being used, has a better effect and is favorable for wide application of the acne-removing composition.
The invention is further configured to: the skin care product comprises skin care water, essence, emulsion and cream.
By adopting the technical scheme, the acne-removing composition is added into skin lotion, essence, emulsion and cream, so that the acne-removing composition is wide in application range and convenient to use.
The invention is further configured to: the addition mass of the acne-removing composition is 8-15% of the mass of the skin care product.
The invention is further configured to: the addition mass of the acne-removing composition is 10% of the mass of the skin care product.
By adopting the technical scheme, the addition amount of the acne-removing composition is controlled, so that the acne-removing composition can better exert the repairing effect, and meanwhile, the skin barrier function of the skin care product is enhanced.
In conclusion, the invention has the following beneficial effects:
1. the safflower extract, the salvia miltiorrhiza extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol are compounded for use, so that the components can be mutually cooperated and mutually promoted, the skin repair and conditioning are facilitated, acne residual pockmarks are effectively removed, and the important barrier function of the skin is maintained;
2. the acne-removing composition can be obtained by uniformly mixing and stirring the components according to the mass part ratio, is simple to operate, saves the production and preparation time, and is beneficial to improving the production efficiency;
3. the acne-removing composition is added into the skin care product, so that the acne-removing effect of the skin care product is improved, and meanwhile, when the skin care product is used, the skin repair and the skin barrier function recovery can be enhanced, and the acne-removing composition is widely applied.
Detailed Description
The present invention will be described in further detail with reference to examples.
In the following examples, safflower extract was obtained from Guangzhou Ruan Bio-technology Co.
In the following examples, the extract of Salvia miltiorrhiza is obtained from Guangzhou Ruian scientific and biological Co.
In the following examples, leonurus tenuifolius extract was extracted from leonurus tenuifolius of Guangzhou Ruan Biotech Co.
In the following examples, saffron extract was obtained from Guangzhou Ruan Bio-technology Ltd.
In the following examples, bis-diethoxydiol cyclohexane 1, 4-dicarboxylate was used from Japanese Kogyo Co., Ltd.
In the following examples, polyquaternium-73 was obtained from the reagent of veting in France.
In the following examples, propylene glycol was obtained from Xianchuan International trade (Shanghai) Co.
Example 1
An acne-removing composition comprises the following components:
11kg of safflower extract, 12kg of salvia miltiorrhiza root extract, 7kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and 8.05kg of propylene glycol.
The preparation method of the acne-removing composition comprises the following steps:
11kg of safflower extract, 12kg of salvia miltiorrhiza root extract, 7kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and 8.05kg of propylene glycol are added into a stirring kettle, and stirred at the normal temperature at the rotating speed of 120r/min to uniformly mix the components, so that the acne-removing composition can be obtained.
Example 2
The difference from example 1 is that: 18kg of safflower extract, 19kg of salvia miltiorrhiza root extract, 11kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and 15.05kg of propylene glycol are added into a stirring kettle.
Example 3
The difference from example 1 is that: 24kg of safflower extract, 27kg of salvia miltiorrhiza root extract, 15kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and 18.15kg of propylene glycol are added into a stirring kettle.
Example 4
The difference from example 1 is that: 20kg of safflower extract, 20kg of salvia miltiorrhiza root extract, 10kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and 14.95kg of propylene glycol are added into a stirring kettle.
Example 5
The difference from example 4 is that: 18kg of herba Leonuri extract is also added into the stirring kettle.
Example 6
The difference from example 4 is that: 30kg of herba Leonuri extract is also added into the stirring kettle.
Example 7
The difference from example 4 is that: 25kg of herba Leonuri extract is also added into the stirring kettle.
Example 8
The difference from example 4 is that: 6kg of saffron extract is also added into the stirring kettle.
Example 9
The difference from example 4 is that: 15kg of saffron extract is also added into the stirring kettle.
Example 10
The difference from example 4 is that: 10kg of saffron extract is also added into the stirring kettle.
Example 11
The difference from example 4 is that: polyquaternary ammonium salt-730.02 kg is also added into the stirring kettle.
Example 12
The difference from example 4 is that: polyquaternary ammonium salt-730.15 kg is also added into the stirring kettle.
Example 13
The difference from example 4 is that: polyquaternary ammonium salt-730.05 kg is also added into the stirring kettle.
Example 14
The difference from example 10 is that: polyquaternary ammonium salt-730.02 kg is also added into the stirring kettle.
Example 15
The difference from example 10 is that: polyquaternary ammonium salt-730.15 kg is also added into the stirring kettle.
Example 16
The difference from example 10 is that: polyquaternary ammonium salt-730.05 kg is also added into the stirring kettle.
Example 17
The difference from example 4 is that: 18kg of herba leonuri extract, 6kg of saffron extract and-730.02 kg of polyquaternium are also added into the stirring kettle.
Example 18
The difference from example 4 is that: 30kg of herba leonuri extract, 15kg of saffron extract and-730.05 kg of polyquaternium are also added into the stirring kettle.
Example 19
The difference from example 4 is that: 25kg of herba leonuri extract, 10kg of saffron extract and-730.05 kg of polyquaternium are also added into the stirring kettle.
Comparative example 1
The difference from example 4 is that: the safflower extract was not added to the stirred tank.
Comparative example 2
The difference from example 4 is that: the Salvia miltiorrhiza root extract was not added to the stirred tank.
Comparative example 3
The difference from example 4 is that: the stirred tank was not charged with bis-diethoxydiol cyclohexane 1, 4-dicarboxylate.
Comparative example 4
The difference from example 4 is that: no propylene glycol was added to the stirred tank.
Experimental group 1
Taking 100mL of skin lotion of a Beijing east self-office store of a Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 1 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 2
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 2 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 3
Taking 100mL of skin lotion of a Beijing Dong self-office store of a Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 3 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 4
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 4 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 5
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 5 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 6
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 6 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 7
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 7 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 8
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 8 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 9
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 9 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 10
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 10 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 11
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 11 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 12
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 12 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 13
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 13 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 14
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 14 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 15
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 15 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 16
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 16 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 17
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 17 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 18
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the example 18 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experimental group 19
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the embodiment 19 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 1
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the comparative example 1 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 2
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the comparative example 2 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 3
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the comparative example 3 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 4
Taking 100mL of skin lotion of the Beijing self-operated official store of the Baique Ling flagship store, adding 10% of the acne-removing composition prepared in the comparative example 4 into 100mL of skin lotion, namely adding 10mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 5
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 5% of the acne-removing composition prepared in the example 19 into 100mL of skin lotion, namely adding 5mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 6
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 18% of the acne-removing composition prepared in the embodiment 19 into 100mL of skin lotion, namely adding 18mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 7
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 8% of the acne-removing composition prepared in the embodiment 19 into 100mL of skin lotion, namely adding 8mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Control group 8
Taking 100mL of skin lotion of the Beijing self-office store of the Baique Ling flagship store, adding 15% of the acne-removing composition prepared in the example 19 into 100mL of skin lotion, namely adding 15mL of the acne-removing composition, and uniformly mixing and stirring to obtain the skin lotion with the acne-removing effect.
Experiment 1
20 volunteers with residual acne marks after skin acne is eliminated are randomly selected from each group, the age of the volunteers is 15-22 years old, 10 volunteers in each group are male and 10 female volunteers, no history of skin and systemic diseases exists, and hormone medicines are not used in the last month. The volunteers take 2mL of the skin care lotion with the acne removing effect prepared by the corresponding experimental group or the control group every day, respectively apply the skin care lotion to the acne mark of the skin in the morning and at the evening, and use the skin care lotion for 30 days.
Detection 1
The curative effect index (%) is calculated according to the degree of improvement of the skin, and the curative effect is judged. And (4) judging the standard: acne-free marks are 0 point; 1 minute at 1-3 parts of acne marks; 2 minutes at 4-6 parts of acne marks; the number of acne marks is 3 at 7-20 points; acne marks greater than 20 were 4 points.
Figure BDA0002318199470000141
Wherein: pre-treatment total score, which is the sum of the pre-skin care water fractions of each group of volunteers; total score after treatment, the sum of the scores of each group of volunteers after applying the skin lotion was added.
Evaluation criteria: the basic cure is achieved, and the curative effect index is more than 75 percent; obvious effect, curative effect index: 50-75%; effective, therapeutic index: 20-49%; no effect, and curative effect index less than 20%.
Detection 2
The skin moisture content of the volunteers of experiment 1 was measured periodically at room temperature using a skin moisture meter CorneometerCM825, manufactured by Courage + Khazaka (CK) of Germany, and the average (%) of the skin moisture content of the volunteers of each group was recorded.
The data from the above experiments are shown in Table 1.
TABLE 1
Figure BDA0002318199470000142
Figure BDA0002318199470000151
According to the comparison of the data of the experimental group 4 and the control groups 1-4 in the table 1, the self-repair of the skin can be promoted only when the safflower extract, the salvia miltiorrhiza extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol are cooperatively matched with each other, so that the skin lotion added with the acne-removing composition has a remarkable effect, is beneficial to timely eliminating residual marks after acne removal, is also beneficial to supplementing skin water and keeping moisture, is lack of any component, and is easy to influence the effect of the acne-removing composition.
According to the comparison of the data of the experimental group 4 and the experimental groups 5-7 in the table 1, the synergistic cooperation of the safflower extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol can be better promoted by adding the leonurus tenuifolius extract, so that the acne-removing composition can further promote the metabolism of skin cells and accelerate the skin repair after being added into skin care water, thereby more effectively eliminating acne residual marks and having better effect.
According to the comparison of the data of the experimental group 4 and the experimental groups 8-10 in the table 1, the synergistic cooperation of the safflower extract, the salvia miltiorrhiza root extract, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate and the propylene glycol can be better promoted by adding the saffron extract, so that the skin moisturizer added with the acne-removing composition can better promote the self-repair of the skin, and is also beneficial to better improving the skin moisture-locking performance, thereby better improving the resistance of the skin in the long-acting moisturizing process, and the effect is more remarkable.
According to the comparison of the data of the experimental groups 8-16 in the table 1, only when the polyquaternium-73 and the saffron crocus extract are cooperated with each other, the promotion effect can be better played, so that the acne-removing composition has a better effect, the effective components of the acne-removing composition are easily absorbed by the skin, the skin repair and long-acting skin moisturizing are better promoted, the effect is quicker, and the effect of the acne-removing composition is easily influenced due to the absence of any component.
According to the comparison of the data of the experimental group 19 and the control groups 5-8 in the table 1, the acne-removing composition can better exert the function by controlling the adding amount of the acne-removing composition, so that the skin lotion added with the acne-removing composition can better exert the repairing effect, and the skin barrier function of the skin care product can be enhanced.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.

Claims (10)

1. An acne-removing composition is characterized in that: the paint comprises the following components in parts by mass:
11-24 parts of safflower extract;
12-27 parts of salvia miltiorrhiza root extract;
7-15 parts of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester;
8.05-18.15 parts of propylene glycol.
2. The acne-removing composition according to claim 1, wherein: the paint also comprises the following components in parts by mass:
18-30 parts of leonurus tenuifolius extract.
3. The acne-removing composition according to any one of claims 1-2, which is characterized by: the paint also comprises the following components in parts by mass:
6-15 parts of saffron extract.
4. The acne-removing composition according to claim 3, wherein: the paint also comprises the following components in parts by mass:
0.15 part of polyquaternium-730.02.
5. A process for the preparation of an anti-acne composition according to any of claims 1 to 4, characterized in that: the acne removing composition can be obtained by mixing and stirring the components of the acne removing composition uniformly according to the parts by mass.
6. The preparation method of the acne-removing composition according to claim 5, which is characterized by comprising the following steps: the acne removing composition is uniformly mixed and stirred at normal temperature.
7. Use of an anti-acne composition according to any of claims 1 to 4, characterized in that: the acne-removing composition is added into a skin care product.
8. Use of an anti-acne composition according to claim 7, characterized in that: the skin care product comprises skin care water, essence, emulsion and cream.
9. Use of an anti-acne composition according to claim 7, characterized in that: the addition mass of the acne-removing composition is 8-15% of the mass of the skin care product.
10. Use of an anti-acne composition according to claim 9, characterized in that: the addition mass of the acne-removing composition is 10% of the mass of the skin care product.
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