CN109172759A - 一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法 - Google Patents
一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法 Download PDFInfo
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Abstract
本发明涉及一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法,属于家禽疾病治疗药物技术领域。技术方案是:各原料药及质量百分比为:败酱草6%、黄芪6%、川芎6%、路路通6%、白芍6%、桃仁6%、香附6%、石菖蒲6%、皂角刺6%、通草4%、当归3%、熟地3%、赤芍3%、薏苡仁3%、紫花地丁3%、白术3%、防风3%、鱼腥草3%、金银花3%、女贞子3%、煅龙骨3%、煅牡蛎3%、枸杞子3%、川牛膝3%。本发明的积极效果:清热解毒,利水消肿,补肾填精,用于治疗IBV侵害鸡只所引起的发热、咳嗽、气管啰音、喷嚏、脱水及输卵管损伤等。
Description
技术领域
本发明涉及一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法,属于家禽疾病治疗药物技术领域。
背景技术
鸡传染性支气管炎(Infectious bronchitis,IB)是由鸡传染性支气管炎病毒(Infectious bronchitisvirus,IBV)引起的急性、高度接触性传染病。IBV主要侵害鸡的呼吸道、泌尿生殖道、消化道等。临床主要表现为咳嗽、气管啰音、喷嚏、肾脏病变、产蛋鸡群产蛋量及蛋品质下降。有资料显示,20日龄以内的雏鸡感染IBV后,除了引起一定的伤亡外,还可引起一定比例的鸡输卵管损伤(包括输卵管退化、输卵管狭窄、输卵管积液等),使其成为表面上正常但不产蛋的假产蛋鸡。由于这种鸡群在开产之前从外观发育如鸡冠、个体大小、耻骨间距大小等尚无方法辨别,因此往往给养鸡生产带来难以估量的经济损失。
发明内容
本发明的目的是提供一种治疗鸡传染性支气管炎并能抗输卵管损伤的中药制剂及其制备方法,该中药制剂能够治疗鸡传染性支气管炎,还具有抗输卵管损伤的特点,疗效高、使用方便、无毒副作用,解决背景技术存在的上述问题。
本发明的技术方案是:
一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂,各原料药及质量百分比为:败酱草6%、黄芪6%、川芎6%、路路通6%、白芍6%、桃仁6%、香附6%、石菖蒲6%、皂角刺6%、通草4%、当归3%、熟地3%、赤芍3%、薏苡仁3%、紫花地丁3%、白术3%、防风3%、鱼腥草3%、金银花3%、女贞子3%、煅龙骨3%、煅牡蛎3%、枸杞子3%、川牛膝3%。
一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法,工艺步骤如下:
①重量百分比选取原料药:败酱草6%、黄芪6%、川芎6%、路路通6%、白芍6%、桃仁6%、香附6%、石菖蒲6%、皂角刺6%、通草4%、当归3%、熟地3%、赤芍3%、薏苡仁3%、紫花地丁3%、白术3%、防风3%、鱼腥草3%、金银花3%、女贞子3%、煅龙骨3%、煅牡蛎3%、枸杞子3%、川牛膝3%;
②将上述原料药混匀,加入为原料药总重量5倍的水浸泡30分钟,然后大火煮沸,再文火煎煮30分钟,过滤,滤出药液;再将药渣中加入为原料药总重量3倍的水,大火煮沸,再文火煎煮45分钟,过滤,滤出药液;合并两次药液,混匀,备用;
③制粒:用浓缩法将以上合并混匀的药液水分蒸发掉,直至成浸膏状,得到浓缩药物,浓缩药物重量为原料药总重量的20%,然后加入为浓缩药物重量1.5倍量的无水葡萄糖,混匀,经60-65℃烘干,制成可溶性颗粒,装袋,密封保存备用。
本发明中各原料药的特点和作用如下:
1、败酱草:辛、苦、微寒。入胃、大肠、肝经。功效:清热解毒,消痈排脓,祛瘀止痛。
2、黄芪:甘、微温。入脾、肺经。功效:益卫固表,补气升阳,托毒生肌,利水消肿。
3、川芎:辛,温,入肝、胆、心包经。功效:活血行气,祛风止痛。
4、路路通:苦、平、微涩。入肝、肾经。功效:祛风活络,利水通经。
5、白芍:味苦,酸,微寒,入肝、脾经。功效:养血敛阴,柔肝止痛,平抑肝阳。
6、桃仁:苦、平。入心、肝、肺、大肠经。功效:活血祛瘀,润肠通便。
7、香附:辛,微苦,微甘,平,入肝,三焦经。功效:疏肝理气,调经止痛。
8、石菖蒲:辛、温。入心、胃经。功效:祛痰开窍,化湿开胃。
9、皂角刺:辛、温。入肝、胃经。功效:消肿托毒,排脓,杀虫。
10、通草:甘、淡、微寒,入肺、胃经。功效:清热利水。
11、当归:甘、辛、温。入肝、心、脾经。功效:活血止痛,润肠通便。
12、熟地:甘、微温。入肝、肾经。功效:养血滋阴,补精益肾。
13、赤芍:苦、微寒。入肝经。功效:清热凉血,活血化瘀,止痛。
14、薏苡仁:甘、淡、微寒。入脾、胃、肺经。功效:利水渗湿,健脾止泻,祛湿除痹,清热排脓。
15、紫花地丁:苦、辛、寒。入心、肝经。功效:清热解毒,凉血消肿。
16、白术:苦、甘、温。入脾、胃经。功效:补气健脾,燥湿利水。
17、防风:辛、甘、微温。入膀胱、肝、脾。功效:祛风解表,胜湿止痛,止痉。
18、鱼腥草:苦、微寒。入肺、大肠、膀胱经。功效:清热解毒,消痈排脓,利水消肿,通淋。
19、金银花:甘、寒。入心、肺、胃经。功效:清热解毒,凉散风热。
20、女贞子:甘、苦、凉。入肝、肾经。功效:补益肝肾,明目,清虚热。
21、煅龙骨:甘、涩、平。入心、肝、肾、大肠经。功效:收敛元气,益精填髓。
22、煅牡蛎:咸、微寒。入肝、肾经。功效:软坚散结、收敛固涩、益精填髓。
23、枸杞子:甘、平。入肝、肾、肺经。功效:滋补肝肾,明目,润肺。
24、川牛膝:甘、微苦、平。入肝、肾经。功效:活血祛瘀,补肝肾,强筋骨,利尿通淋。
方中败酱草清热解毒,消肿祛瘀;黄芪补气升阳,脱毒生肌,利水消肿;川芎活血行气;路路通祛风活络,利水通经。以上四药共为君药,以达清热解毒、祛瘀通经、托毒消肿之功。桃仁活血祛瘀;香附理气调经,二者相须,祛瘀通经。白芍养血敛阴;石菖蒲祛痰化湿、皂角刺消肿托毒、通草清热利水,以上诸药共为臣药,辅君药,共凑清热解毒、利水消肿、养血通管之功。当归活血补血;熟地养血滋阴,补精益肾;赤芍清热凉血,活血化瘀;薏苡仁清热利水;紫花地丁清热解毒;白术补气燥湿;防风祛风胜湿,利膀胱;鱼腥草清热解毒,利水通淋;金银花清热解毒;女贞子、煅龙骨、枸杞子、煅牡蛎补益肝肾、滋补卵巢、有益排卵,利于蛋壳的生成,以上诸药共为佐药,共凑清热化瘀、补益肝肾之功。川牛膝为使药,引药下行,以达病所。全方配伍起到标本同治,既可清热解毒,以抗病毒;利水消肿,以益通管;又可补肾填精,以促排卵。真正起到急能治其标,缓能治其本的作用。
本发明的积极效果:清热解毒,利水消肿,补肾填精,用于治疗IBV侵害鸡只所引起的发热、咳嗽、气管啰音、喷嚏、脱水及输卵管损伤等。
具体实施方式
下面结合实施例对本发明做进一步的说明:在实施例中,一种治疗鸡传染性支气管炎中药制剂,包括败酱草60g、黄芪60g、川芎60g、路路通60g、白芍60g、桃仁60g、香附60g、石菖蒲60g、皂角刺60g、通草40g、当归30g、熟地30g、赤芍30g、薏苡仁30g、紫花地丁30g、白术30g、防风30g、鱼腥草30g、金银花30g、女贞子30g、煅龙骨30g、煅牡蛎30g、枸杞子30g、川牛膝30g。
一种治疗鸡传染性支气管炎并抗输卵管损伤中药制剂的制备方法,其工艺步骤如下:
①选取原料药:败酱草60g、黄芪60g、川芎60g、路路通60g、白芍60g、桃仁60g、香附60g、石菖蒲60g、皂角刺60g、通草40g、当归30g、熟地30g、赤芍30g、薏苡仁30g、紫花地丁30g、白术30g、防风30g、鱼腥草30g、金银花30g、女贞子30g、煅龙骨30g、煅牡蛎30g、枸杞子30g、川牛膝30g,原料药总重量为1000g;
②将上述原料药混匀,加入5000g的水浸泡30分钟,然后大火煮沸,再文火煎煮30分钟,过滤,滤出药液;再将药渣中重新加入3000g水分,先大火煮沸,再文火煎煮45分钟,过滤,滤出药液;合并两次药液,混匀,备用;
③制粒:用浓缩法将以上合并混匀的药液水分蒸发掉,直至成浸膏状,得到浓缩药物,浓缩药物重量为200g,然后加入300g无水葡萄糖,混匀,经60-65℃烘干,制成可溶性颗粒,装袋,密封保存备用。
用法用量:每日按鸡每公斤体重用可溶性颗粒3~5克,加可溶性颗粒重量2~3倍的水,混合后饮用,每天两次,连用10天。
Claims (2)
1.一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂,其特征在于:各原料药及质量百分比为:败酱草6%、黄芪6%、川芎6%、路路通6%、白芍6%、桃仁6%、香附6%、石菖蒲6%、皂角刺6%、通草4%、当归3%、熟地3%、赤芍3%、薏苡仁3%、紫花地丁3%、白术3%、防风3%、鱼腥草3%、金银花3%、女贞子3%、煅龙骨3%、煅牡蛎3%、枸杞子3%、川牛膝3%。
2.一种治疗鸡传染性支气管炎并抗输卵管损伤的中药制剂及其制备方法,其特征在于如下工艺步骤:
①按重量百分比选取原料药:败酱草6%、黄芪6%、川芎6%、路路通6%、白芍6%、桃仁6%、香附6%、石菖蒲6%、皂角刺6%、通草4%、当归3%、熟地3%、赤芍3%、薏苡仁3%、紫花地丁3%、白术3%、防风3%、鱼腥草3%、金银花3%、女贞子3%、煅龙骨3%、煅牡蛎3%、枸杞子3%、川牛膝3%;
②将上述原料药混匀,加入为原料药总重量5倍的水浸泡30分钟,然后大火煮沸,再文火煎煮30分钟,过滤,滤出药液;再将药渣中加入为原料药总重量3倍的水,大火煮沸,再文火煎煮45分钟,过滤,滤出药液;合并两次药液,混匀,备用;
③制粒:用浓缩法将以上合并混匀的药液水分蒸发掉,直至成浸膏状,得到浓缩药物,浓缩药物重量为原料药总重量的20%,然后加入为浓缩药物重量1.5倍量的无水葡萄糖,混匀,经60-65℃烘干,制成可溶性颗粒,装袋,密封保存备用。
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