CN109125254A - 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 - Google Patents

吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 Download PDF

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Publication number
CN109125254A
CN109125254A CN201811072429.6A CN201811072429A CN109125254A CN 109125254 A CN109125254 A CN 109125254A CN 201811072429 A CN201811072429 A CN 201811072429A CN 109125254 A CN109125254 A CN 109125254A
Authority
CN
China
Prior art keywords
composite
morphine
dihydrate
buffer
months
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811072429.6A
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English (en)
Chinese (zh)
Inventor
阿莱纳·屈内
迪迪埃·瓦罗
波利娜·罗曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Deutschland GmbH
Original Assignee
Fresenius Kabi Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Deutschland GmbH filed Critical Fresenius Kabi Deutschland GmbH
Publication of CN109125254A publication Critical patent/CN109125254A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201811072429.6A 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 Pending CN109125254A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361785218P 2013-03-14 2013-03-14
US61/785,218 2013-03-14
CN201410097764.7A CN104042565A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201410097764.7A Division CN104042565A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Publications (1)

Publication Number Publication Date
CN109125254A true CN109125254A (zh) 2019-01-04

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201811072429.6A Pending CN109125254A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途
CN201410097764.7A Pending CN104042565A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Family Applications After (1)

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CN201410097764.7A Pending CN104042565A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Country Status (8)

Country Link
US (7) US9072781B2 (https=)
EP (2) EP2968132B1 (https=)
JP (1) JP6215970B2 (https=)
CN (2) CN109125254A (https=)
AU (1) AU2014230834B9 (https=)
BR (1) BR112015021586B1 (https=)
CA (1) CA2902343C (https=)
WO (1) WO2014140095A1 (https=)

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ES2988823T3 (es) 2014-12-03 2024-11-21 Csl Behring Ag Producto farmacéutico con mayor estabilidad que comprende inmunoglobulinas
US20170189352A1 (en) 2015-03-13 2017-07-06 Par Pharmaceutical, Inc. Epinephrine formulations
US9119876B1 (en) 2015-03-13 2015-09-01 Par Pharmaceutical, Inc. Epinephrine formulations
US11369700B2 (en) 2015-05-25 2022-06-28 IGL Pharma Inc. DOTMP kit formulations for radioisotopes
WO2016191413A1 (en) * 2015-05-25 2016-12-01 Iso Therapeutics Group, Llc Dotmp kit formulations for radioisotopes
US20180064703A1 (en) * 2016-09-02 2018-03-08 Sun Pharmaceutical Industries Ltd. Stable infusion dosage form of morphine
EP3515412B1 (en) * 2016-09-23 2025-04-23 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
WO2019183416A1 (en) 2018-03-23 2019-09-26 Nevakar Inc. Epinephrine compositions and containers
CN114207101B (zh) 2019-07-31 2024-05-31 埃科莱布美国股份有限公司 免用个人防护设备的脱灰剂组合物
US11806320B2 (en) * 2020-02-19 2023-11-07 Endo Ventures Limited Isoproterenol compositions and methods
US20240041866A1 (en) * 2020-12-18 2024-02-08 Fujifilm Toyama Chemical Co., Ltd. Pharmaceutical composition

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Also Published As

Publication number Publication date
US9192608B2 (en) 2015-11-24
US20230414604A1 (en) 2023-12-28
JP6215970B2 (ja) 2017-10-18
US20190167665A1 (en) 2019-06-06
WO2014140095A1 (en) 2014-09-18
US20150246036A1 (en) 2015-09-03
US20250228846A1 (en) 2025-07-17
JP2016512210A (ja) 2016-04-25
EP2968132A1 (en) 2016-01-20
AU2014230834A1 (en) 2015-09-10
AU2014230834B9 (en) 2017-08-31
US20140275144A1 (en) 2014-09-18
CA2902343A1 (en) 2014-09-18
US20200345720A1 (en) 2020-11-05
US10213424B2 (en) 2019-02-26
US20160175297A1 (en) 2016-06-23
CA2902343C (en) 2022-08-02
AU2014230834B2 (en) 2017-08-03
EP3143988A1 (en) 2017-03-22
EP2968132B1 (en) 2017-09-13
US9072781B2 (en) 2015-07-07
CN104042565A (zh) 2014-09-17
BR112015021586A2 (pt) 2017-07-18
BR112015021586B1 (pt) 2023-01-31

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Application publication date: 20190104