CN109106651B - Wrinkle-removing firming cream and preparation method thereof - Google Patents
Wrinkle-removing firming cream and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract
The invention relates to a wrinkle-removing firming cream and a preparation method thereof. The wrinkle-removing firming cream comprises the following components in percentage by weight: 1.5-2.5% of polydimethylsiloxane PEG10/15 cross-linked polymer, 0.8-1.3% of lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, 5.4-6.5% of polydimethylsiloxane, 0.8-1.2% of plant extract, 3.5-4.6% of cyclopenta polydimethylsiloxane, 1.6-2.4% of vinyl polydimethylsiloxane cross-linked polymer cyclopenta polydimethylsiloxane, 0.03-0.07% of essence, 4-6% of glycerol, 8-12% of 1, 3-propylene glycol, 0.8-1.3% of sodium chloride, 0.8-1.1% of bacteriostatic agent, 4.7-5.2% of hydrolyzed vegetable protein and the balance of deionized water. The wrinkle-removing firming cream has the characteristics of natural components, good wrinkle-removing effect, improvement on skin characteristics and the like. The invention further discloses a preparation method of the wrinkle-removing firming cream. The preparation method of the wrinkle-removing firming cream has simple preparation process and simple operation, avoids the complex preparation process of the cream in the prior art, and can effectively reduce the production cost.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a wrinkle-removing firming cream and a preparation method thereof.
Background
Facial and periocular regions are fragile areas of the entire skin, and a series of facial or ocular problems such as dark circles, bags, wrinkles, etc. occur due to night out, poor sleep, aging, chemical irritation, etc.
The wrinkle-removing and firming cream is a wrinkle-removing and firming product aiming at wrinkles on the face or eyes, is one of the most popular products in cosmetic development, and is also a target which is constantly pursued by technical developers. However, the existing wrinkle-removing and firming cream has limited wrinkle-removing effect, cannot help skin to improve elasticity, and has poor using effect. In addition, the existing preparation method of the wrinkle-removing firming cream has complex process and high production cost.
Disclosure of Invention
Based on the above, the invention aims to provide a wrinkle-removing and firming cream and a preparation method thereof.
The wrinkle-removing firming cream comprises the following components in percentage by weight:
further preferably, the paint comprises the following components in percentage by weight:
further preferably, the plant extract comprises one or more of safflower seed oil, jambu flower extract, astragalus membranaceus root extract, ubiquinone and tocopherol.
Further preferably, the bacteriostatic agent comprises caprylhydroxamic acid and/or glyceryl caprylate.
Further preferably, the essence is a daisy essence.
The wrinkle-removing firming cream has the characteristics of natural components, good wrinkle-removing effect, improvement on skin characteristics and the like.
The invention further provides a preparation method of the wrinkle-removing and firming cream, which is used for preparing any one of the wrinkle-removing and firming cream, and comprises the following steps:
s1, adding lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing to obtain a mixture A;
s2, mixing and quickly stirring the glycerol, the 1, 3-propylene glycol, the sodium chloride, the bacteriostatic agent and the deionized water uniformly, and continuously adding and stirring the hydrolyzed vegetable protein to be mixed and homogenized to obtain a mixture B;
s3, slowly adding the mixture B into the mixture A under the condition of stirring, and emulsifying uniformly to obtain a mixture C;
and S4, after emulsification, continuously stirring and uniformly dispersing the mixture C to obtain the wrinkle-removing and firming cream.
Further preferably, in S1, the lauryl PEG-9 dimethiconoethyl polydimethylsiloxane is added to the dimethicone PEG10/15 cross-linked polymer and mixed uniformly, and then homogenized for 3-8min, and the dimethicone, the plant extract, the cyclopentadimethylsiloxane, the vinyl dimethicone cross-linked polymer cyclopentadimethylsiloxane and the essence are added continuously and mixed uniformly for 2-5min, so as to obtain a mixture a.
Further preferably, in the step S4, after emulsification, the mixture C is continuously stirred and uniformly dispersed at the speed of 4500-5500r/min, so as to prepare the wrinkle-removing and tightening cream.
The preparation method of the wrinkle-removing firming cream has simple preparation process and simple operation, avoids the complex preparation process of the cream in the prior art, and can effectively reduce the production cost.
Detailed Description
Example one
The wrinkle-removing and firming cream comprises the following components in percentage by weight:
the plant extracts of this example include safflower seed oil, jambu flower extract, and astragalus membranaceus root extract.
The plant extracts of the embodiment, namely the safflower seed oil, the spilanthes herb extract and the astragalus membranaceus root extract, can achieve a multifunctional tightening and lifting effect and reduce deep wrinkles.
The extract of the said flos Trollii can act on the subcutaneous tense muscle, and is beneficial to the vasodilatation and antioxidant activity, bringing about the rapid muscle relaxation effect, inhibiting the skin contraction.
The extract of the root of Astragalus membranaceus bge can prevent collagen degradation caused by ultraviolet irradiation light aging, promote fibroblast, and delay aging by affecting telomerase activity.
The ubiquinone can enhance the synthesis of basement membrane components, prevent photoaging, reduce DNA damage due to UAV irradiation, and reduce facial fine lines and wrinkle depth.
The tocopherol acts synergistically with other ingredients to facilitate absorption.
The hydrolyzed vegetable protein is an effective component for safely increasing skin elasticity, can be completely dissolved in water, is an efficient film-forming protein, can reduce fine lines and wrinkles, and can remold and smooth skin. The hydrolyzed vegetable protein of this embodiment is preferably hydrolyzed American potato protein.
The plant extract and the hydrolyzed plant protein are effective active ingredients of the wrinkle-removing firming cream.
The polydimethylsiloxane PEG10/15 cross-linked polymer and the polydimethylsiloxane can form a space frame structure, and can be embedded with water phase liquid drops to form an innovative emulsification structure, so that the stability of effective active ingredients can be fully ensured, and a slow release function is created, so that the instant effect of instant action is realized, the effect of long-acting active ingredients is realized, and the wrinkle removing effect is obvious.
The bacteriostatic agent comprises caprylyl hydroximic acid.
The essence of this embodiment is daisy essence.
The wrinkle-removing firming cream provided by the embodiment not only meets the stability of active ingredients, ensures the long-acting slow release of the active ingredients, greatly improves the utilization efficiency of active ingredients such as aureobasil in the aureobasidium extract, and has the wrinkle-removing effect.
The preparation method of the wrinkle-removing and firming cream provided by the embodiment is used for preparing the wrinkle-removing and firming cream provided by the embodiment, and comprises the following steps:
s1, adding lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing for 3min, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing for 2min to obtain a mixture A;
s2, mixing and quickly stirring the glycerol, the 1, 3-propylene glycol, the sodium chloride, the bacteriostatic agent and the deionized water uniformly, and continuously adding and stirring the hydrolyzed vegetable protein to be mixed and homogenized to obtain a mixture B;
s3, slowly adding the mixture B into the mixture A under the condition of stirring, and emulsifying uniformly to obtain a mixture C;
and S4, after emulsification, continuously stirring and uniformly dispersing the mixture C at the speed of 4500r/min to prepare the wrinkle-removing and firming cream.
Example two
The wrinkle-removing and firming cream comprises the following components in percentage by weight:
the plant extracts of the embodiment comprise safflower seed oil, jambu flower extract, astragalus membranaceus root extract and ubiquinone, and can achieve a multifunctional tightening and lifting effect and reduce deep wrinkles.
The extract of the said flos Trollii can act on the subcutaneous tense muscle, and is beneficial to the vasodilatation and antioxidant activity, bringing about the rapid muscle relaxation effect, inhibiting the skin contraction.
The extract of the root of Astragalus membranaceus bge can prevent collagen degradation caused by ultraviolet irradiation light aging, promote fibroblast, and delay aging by affecting telomerase activity.
The ubiquinone can enhance the synthesis of basement membrane components, prevent photoaging, reduce DNA damage due to UAV irradiation, and reduce facial fine lines and wrinkle depth.
The tocopherol acts synergistically with other ingredients to facilitate absorption.
The hydrolyzed vegetable protein is an effective component for safely increasing skin elasticity, can be completely dissolved in water, is an efficient film-forming protein, can reduce fine lines and wrinkles, and can remold and smooth skin. The hydrolyzed vegetable protein of this embodiment is preferably hydrolyzed American potato protein.
The plant extract and the hydrolyzed plant protein are effective active ingredients of the wrinkle-removing firming cream.
The polydimethylsiloxane PEG10/15 cross-linked polymer and the polydimethylsiloxane can form a space frame structure, and can be embedded with water phase liquid drops to form an innovative emulsification structure, so that the stability of effective active ingredients can be fully ensured, and a slow release function is created, so that the instant effect of instant action is realized, the effect of long-acting active ingredients is realized, and the wrinkle removing effect is obvious.
The bacteriostatic agent comprises glyceryl caprylate.
The essence of this embodiment is daisy essence.
The wrinkle-removing firming cream provided by the embodiment not only meets the stability of active ingredients, ensures the long-acting slow release of the active ingredients, greatly improves the utilization efficiency of active ingredients such as aureobasil in the aureobasidium extract, and has the wrinkle-removing effect.
The preparation method of the wrinkle-removing and firming cream provided by the embodiment is used for preparing the wrinkle-removing and firming cream provided by the embodiment, and comprises the following steps:
s1, adding lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing for 8min, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing for 5min to obtain a mixture A;
s2, mixing and quickly stirring the glycerol, the 1, 3-propylene glycol, the sodium chloride, the bacteriostatic agent and the deionized water uniformly, and continuously adding and stirring the hydrolyzed vegetable protein to be mixed and homogenized to obtain a mixture B;
s3, slowly adding the mixture B into the mixture A under the condition of stirring, and emulsifying uniformly to obtain a mixture C;
and S4, after emulsification, continuously stirring and uniformly dispersing the mixture C at a speed of 5500r/min to prepare the wrinkle-removing and firming cream.
EXAMPLE III
The wrinkle-removing and firming cream comprises the following components in percentage by weight:
the plant extracts of the embodiment comprise safflower seed oil, jambu flower extract, astragalus membranaceus root extract, ubiquinone and tocopherol, and can achieve a multifunctional tightening and lifting effect and reduce deep wrinkles.
The extract of the said flos Trollii can act on the subcutaneous tense muscle, and is beneficial to the vasodilatation and antioxidant activity, bringing about the rapid muscle relaxation effect, inhibiting the skin contraction.
The extract of the root of Astragalus membranaceus bge can prevent collagen degradation caused by ultraviolet irradiation light aging, promote fibroblast, and delay aging by affecting telomerase activity.
The ubiquinone can enhance the synthesis of basement membrane components, prevent photoaging, reduce DNA damage due to UAV irradiation, and reduce facial fine lines and wrinkle depth.
The tocopherol acts synergistically with other ingredients to facilitate absorption.
The hydrolyzed vegetable protein is an effective component for safely increasing skin elasticity, can be completely dissolved in water, is an efficient film-forming protein, can reduce fine lines and wrinkles, and can remold and smooth skin. The hydrolyzed vegetable protein of this embodiment is preferably hydrolyzed American potato protein.
The plant extract and the hydrolyzed plant protein are effective active ingredients of the wrinkle-removing firming cream.
The polydimethylsiloxane PEG10/15 cross-linked polymer and the polydimethylsiloxane can form a space frame structure, and can be embedded with water phase liquid drops to form an innovative emulsification structure, so that the stability of effective active ingredients can be fully ensured, and a slow release function is created, so that the instant effect of instant action is realized, the effect of long-acting active ingredients is realized, and the wrinkle removing effect is obvious.
The bacteriostatic agent comprises caprylyl hydroximic acid and glyceryl caprylate.
The essence of this embodiment is daisy essence.
The wrinkle-removing firming cream provided by the embodiment not only meets the stability of active ingredients, ensures the long-acting slow release of the active ingredients, greatly improves the utilization efficiency of active ingredients such as aureobasil in the aureobasidium extract, and has the wrinkle-removing effect.
The wrinkle-removing firming cream provided by the invention adopts natural active long-acting components, can improve the skin elasticity and refine wrinkles after being used for 28 days, has an obvious wrinkle-removing effect, and can be suitable for the face and eyes.
The preparation method of the wrinkle-removing and firming cream provided by the embodiment is used for preparing the wrinkle-removing and firming cream provided by the embodiment, and comprises the following steps:
s1, adding lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing for 5min, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing for 3min to obtain a mixture A;
s2, mixing and quickly stirring the glycerol, the 1, 3-propylene glycol, the sodium chloride, the bacteriostatic agent and the deionized water uniformly, and continuously adding and stirring the hydrolyzed vegetable protein to be mixed and homogenized to obtain a mixture B;
s3, slowly adding the mixture B into the mixture A under the condition of stirring, and emulsifying uniformly to obtain a mixture C;
and S4, after emulsification, continuously stirring and uniformly dispersing the mixture C at the speed of 5000r/min to prepare the wrinkle-removing and firming cream.
The preparation method of the wrinkle-removing firming cream has simple preparation process and simple operation, avoids the complex preparation process of the cream in the prior art, and can effectively reduce the production cost.
In order to prove the using effect of the wrinkle-removing firming cream, the following trial tests are carried out: 30 healthy volunteers were recruited, the age of the 30 volunteers was distributed between 45-65 years, and the 30 volunteers were divided into A, B, C groups, which respectively tried the wrinkle-removing tightening cream of the first to third examples in turn, and were used before sleeping every night for 28 days continuously.
By adopting sensory and visual evaluation of actual use, 5 points show good, 4 points show good, 3 points show general, 2 points show poor, 1 point shows poor, A, B, C groups of volunteers record data after evaluation, and the evaluation conditions are as follows:
examples | Wrinkle removing effect | Improving skin elasticity |
Example one | 4.5 | 4.3 |
Example two | 4.3 | 4.7 |
EXAMPLE III | 5.0 | 4.9 |
From the trial results, the wrinkle-removing and firming cream of the third embodiment has the best effect, and is the best embodiment, and obvious wrinkle-removing and firming cream and skin elasticity-improving effects can be obtained by using the wrinkle-removing and firming cream.
To further examine the effect of the cream for removing wrinkles and firming of example three, 12 adult white skin volunteers aged 49-60 years were recruited and applied twice a day, on half face with the placebo cream of control, on half face with the cream for removing wrinkles and firming of the present invention, and compared after 28 days and 56 days of use, respectively.
The experimental results are as follows: after 28 days of use, 12 volunteers used the cream of the present invention for reducing wrinkles on the half face, reducing deep wrinkles, and improving skin elasticity, while the half face using the placebo cream was not significantly changed from before use.
After 56 days of use, the wrinkles of the half face of 12 volunteers using the cream for removing and tightening the wrinkles are obviously reduced or even disappeared, the deep wrinkles are obviously thinned, the skin elasticity is obviously improved, and the half face using the placebo cream has no obvious change from the half face before use.
The wrinkle-removing firming cream has the characteristics of natural components, good wrinkle-removing effect, improvement on skin characteristics and the like.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.
Claims (7)
3. the wrinkle-removing tightening cream according to claim 1 or 2, characterized in that: the bacteriostatic agent comprises caprylhydroxamic acid and/or glyceryl caprylate.
4. The wrinkle-removing tightening cream according to claim 1 or 2, characterized in that: the essence is a daisy essence.
5. A method for preparing a wrinkle-removing and firming cream, which is used for preparing the wrinkle-removing and firming cream as claimed in any one of claims 1 to 4, and comprises the following steps:
s1, adding lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing to obtain a mixture A;
s2, mixing and quickly stirring the glycerol, the 1, 3-propylene glycol, the sodium chloride, the bacteriostatic agent and the deionized water uniformly, and continuously adding and stirring the hydrolyzed vegetable protein to be mixed and homogenized to obtain a mixture B;
s3, slowly adding the mixture B into the mixture A under the condition of stirring, and emulsifying uniformly to obtain a mixture C;
and S4, after emulsification, continuously stirring and uniformly dispersing the mixture C to obtain the wrinkle-removing and firming cream.
6. The preparation method of the wrinkle-removing and tightening cream according to claim 5, characterized in that: and in the S1, adding the lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane into the polydimethylsiloxane PEG10/15 cross-linked polymer, uniformly mixing, homogenizing for 3-8min, continuously adding the polydimethylsiloxane, the plant extract, the cyclopentadimethylsiloxane, the vinyl polydimethylsiloxane cross-linked polymer cyclopentadimethylsiloxane and the essence, mixing, and homogenizing for 2-5min to obtain a mixture A.
7. The method for preparing the wrinkle-removing and tightening cream according to claim 5 or 6, characterized in that: and in the S4, after emulsification, continuously stirring and uniformly dispersing the mixture C at the speed of 4500-5500r/min to prepare the wrinkle-removing and tightening cream.
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CN109568209B (en) * | 2019-01-08 | 2021-08-20 | 广州悦荟化妆品有限公司 | Anti-aging, anti-wrinkle and firming essence oil |
CN109820782B (en) * | 2019-03-21 | 2021-09-10 | 伯德创研(广州)生物科技有限公司 | Microemulsion type wrinkle-removing essence and preparation method thereof |
CN111956533A (en) * | 2020-09-29 | 2020-11-20 | 广东丸美生物技术股份有限公司 | Wrinkle-removing cream and preparation method thereof |
CN115364006B (en) * | 2021-12-29 | 2024-02-09 | 皓雨(广州)化妆品制造有限公司 | Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product |
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CN107115240A (en) * | 2017-05-27 | 2017-09-01 | 广州市千邦化妆品有限公司 | A kind of anti-ageing face cream and preparation method thereof that compacts |
CN107157784A (en) * | 2017-07-06 | 2017-09-15 | 广州诚予化妆品有限公司 | It is a kind of that there is facial mask of reparation antianaphylaxis function and preparation method thereof |
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