CN109568209B - Anti-aging, anti-wrinkle and firming essence oil - Google Patents
Anti-aging, anti-wrinkle and firming essence oil Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention provides anti-aging, anti-wrinkle and firming essence oil which mainly comprises the following components in percentage by weight: 0.1-1% of hypecoum extract, 0.1-1% of samaria extract, 0.1-1% of spilanthol extract and 0.1-1% of undaria pinnatifida extract. After the four components are reasonably compounded, the living environment of local tissues and cells is rapidly improved through the active molecules of the plant extracts with affinity action, the metabolism is accelerated, some problems caused by local metabolic disorders are comprehensively solved, the cell metabolism and cell regeneration functions are promoted, the skin wrinkle problem can be obviously improved, and the skin wrinkle-resisting, anti-aging and tightening effects are obvious.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to anti-aging, anti-wrinkle and firming essential oil.
Background
With the increase of age, environmental pollution and living pressure, the skin aging of people is more and more obvious, and the anti-wrinkle, tightening, beauty and skin care are more and more paid more attention by people. Skin aging is usually manifested by decreased skin elasticity, increased skin wrinkles, increased skin roughness, decreased moisturizing intensity, and the like. The simple use of moisturizers in daily life is obviously insufficient for preventing skin aging. Other natural factors such as environment, sunlight, pressure and the like can also promote the skin aging to be accelerated, and the skin is easy to generate spots, fine lines and the like. Meanwhile, years can cause body aging, skin metabolism is slowed down, collagen and elastic tissue fibers of the skin are changed, texture and content are reduced, the skin gradually loses elasticity, becomes loose, and wrinkles appear.
In the market, water aqua or oil-in-water products are mostly used as anti-aging, anti-wrinkle and firming products, so that the development of a pure oil product and the anti-aging, anti-wrinkle and firming product with oil-soluble plant extracts as effective components are necessary.
Disclosure of Invention
Based on the essential oil, the invention aims to provide the essential oil for resisting aging, wrinkles and firming.
The anti-aging, anti-wrinkle and firming essence oil mainly comprises the following components in percentage by weight:
sea fennel extract 0.1-1%
Alarian extract 0.1-1%
Herba Clerodendranthi Spicati extract 0.1-1%
0.1-1% of undaria pinnatifida extract.
The cosmetic of the anise extract according to the present invention, known in the chinese name anise (CRITHMUM MARITIMUM) extract, represents an oil-soluble extract obtained by extraction from anise, a plant growing on rocks exposed to sea waves, which may contain or include one or more bioactive molecules including glycolipids, oleic acid, erucic acid and phytosterols. Suitable hypecoum vulgare extract may comprise NATIVE ESSENCE @ (from BiotechMarine, france).
The winged algae extract is named as algae extract in cosmetics, and is oil soluble extract extracted from winged algae and may contain or include one or several kinds of bioactive molecule, including glycolipid and polypeptide. Suitable winged algae extracts may comprise KALPARIANE AD @ (from BiotechMarine, france).
The invention relates to a jambu flower extract, which is a Chinese name of a jambu (SPILANTHES ACMELLA) flower extract in cosmetics, and represents an oil-soluble extract extracted from a flower of a jambu plant, wherein the effective component of the extract is mainly alkylamide. Suitable extracts of Eupatorium Adenophorum may include GATULINE IN-TENSE (from GATTEFOSS Inc.).
The cosmetic of Undaria PINNATIFIDA (Undaria PINNATIFIDA) extract is named as Undaria PINNATIFIDA (Undaria PINNATIFIDA) extract, and is oil soluble extract extracted from Undaria PINNATIFIDA, and its main components are polyphenol, flavone, etc. with antioxidant effect, which may contain EphemmerTM(from BiotechMarine, France).
In some embodiments, the essence oil for resisting aging, wrinkles and firming also comprises the following components in percentage by mass: 0.1-2% of tocopherol acetate.
In some embodiments, the essence oil for resisting aging, wrinkles and firming also comprises the following components in percentage by mass: caprylic/capric triglyceride 94-99.5%.
In some embodiments, the essence oil for resisting aging, wrinkles and firming comprises the following components in percentage by mass: 0.1% of hypecoum extract, 1% of samaria extract, 0.1% of spilanthes extract, 1% of undaria pinnatifida extract, 95.8% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
In some embodiments, the essence oil for resisting aging, wrinkles and firming comprises the following components in percentage by mass: hypecoum extract 0.5%, pteridium extract 0.5%, herba Clerodendranthi Spicati extract 0.5%, Undaria Pinnatifida extract 0.5%, caprylic/capric triglyceride 96%, and tocopheryl acetate 2%.
The invention has the following advantages and beneficial effects:
(1) the invention adopts oil-soluble plant extract, utilizes the undaria pinnatifida extract containing antioxidant substances, has instant and long-acting antioxidant property, has less free radicals and achieves the anti-aging effect. The Craib anisetree extract contains glycolipid, oleic acid, erucic acid and phytosterol, and can promote the synthesis of ceramide and filaggrin, inhibit lipid peroxidation and inflammatory reaction, reestablish water balance and increase skin glossiness. The winged algae extract contains elastic fiber network (protein and polysaccharide), reduces synthesis of senilism protein in senescent cells, maintains integrity of tissues, and ensures adhesion and compactness of cell structures. The extract of the spilanthes containing alkylamide can stimulate the natural activity of fibroblasts, promote the movement and contraction of the fibroblasts, increase the density in a collagen crystalline network and tighten the skin.
(2) The anti-aging, anti-wrinkle and firming essence oil disclosed by the invention is subjected to a skin percutaneous water loss value (TEWL value) experimental test, and the result shows that the anti-aging, anti-wrinkle and firming essence oil also has a good water locking and moisturizing effect, can be applied to dry skin or water-deficient skin, and has a good moisturizing effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in further detail below. However, the embodiments of the present invention are not limited thereto, and the process parameters or conditions not particularly mentioned may be performed by referring to the conventional techniques.
Experimental group 1
The anti-aging, anti-wrinkle and firming essence oil comprises the following components in percentage by weight:
0.1% of hypecoum extract, 1% of samaria extract, 0.1% of spilanthes extract, 1% of undaria pinnatifida extract, 95.8% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Experimental group 2
The anti-aging, anti-wrinkle and firming essence oil comprises the following components in percentage by weight:
1% of hypecoum extract, 0.1% of samaria extract, 1% of spilanthes extract, 0.1% of undaria pinnatifida extract, 95.8% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Experimental group 3
The anti-aging, anti-wrinkle and firming essence oil comprises the following components in percentage by weight:
hypecoum extract 0.5%, pteridium extract 0.5%, herba Clerodendranthi Spicati extract 0.5%, Undaria Pinnatifida extract 0.5%, caprylic/capric triglyceride 96%, and tocopheryl acetate 2%.
Blank group
A simple essential oil without other active substances comprises the following components in percentage by weight: caprylic/capric triglyceride 98%, tocopheryl acetate 2%.
Control group 1
The essential oil comprises the following components in percentage by weight: 2% of undaria pinnatifida extract, 96% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 2
The essential oil comprises the following components in percentage by weight: 2% of anise extract, 96% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 3
The essential oil comprises the following components in percentage by weight: 2% of algae extract, 96% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 4
The essential oil comprises the following components in percentage by weight: 2% of the extract of the spilanthol, 96% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 5
The essential oil comprises the following components in percentage by weight: 0.7% of undaria pinnatifida extract, 0.7% of hypecoum vulgare extract, 0.7% of algae extract, 95.9% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 6
The essential oil comprises the following components in percentage by weight: 0.7% of the extract of the flower of the golden buttonhole, 0.7% of the extract of the hypecoum vulgare, 0.7% of the extract of the alga, 95.9% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 7
The essential oil comprises the following components in percentage by weight: 0.7% of the extract of the flower of the golden buttonhole, 0.7% of the extract of the undaria pinnatifida, 0.7% of the extract of the algae, 95.9% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Control group 8
The essential oil comprises the following components in percentage by weight: 0.7% of the extract of the flower of the golden buttonhole, 0.7% of the extract of the undaria pinnatifida, 0.7% of the extract of the hypecoum vulgare, 95.9% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
Experiment 1 safety test
Human body patch experiment
150 healthy volunteer subjects with the age of 25-60 years are selected, and 120 volunteers with the age of 35-60 years, obvious facial wrinkles and poor skin elasticity are particularly selected. The male and female are divided into 2 groups, each group comprises 60 persons, each person takes 6 samples, a standard spot tester (Beijing Yida) is selected, about 0.020-0.025g of a tested object is placed in a small chamber of the spot tester by a closed spot test method and is pasted in the arm of a tested person for testing, the spot tester is removed after 24 hours, skin reactions are observed in 0.5 hour, 6 hours, 12 hours, 24 hours and 48 hours respectively, and the results are recorded according to the skin closed spot test skin reaction grading standard in the table 1. Selected volunteers met the criteria.
TABLE 1 skin closed Patch test skin response grading Standard
TABLE 2-3 Patch test records
TABLE 2 test records
TABLE 3 test record
As can be seen from tables 2 and 3, 120 volunteers observed skin reactions at 0.5, 6, 12, 24 and 48 hours by patch tests of the blank group, the control group 1-8 and the experimental group 1-3 described in the present invention, wherein 0 case of skin adverse reactions appeared, which indicates that the blank group, the control group 1-8 and the experimental group 1-3 described in the present invention are safe.
Experiment 2 trial test on population
2.1 elasticity test
The test volunteers: 120 specially selected volunteers of 35-60 years old with obvious facial wrinkles and poor skin elasticity were selected and randomly divided into 12 groups.
And (3) testing a sample: samples from blanks, controls 1-8, and experiments 1-3 described herein.
The using method comprises the following steps: after cleaning the face of a volunteer in the morning and at night every day, 2-3 drops of a sample to be tested are dropped into the palm, the palm is rubbed with the palm, and the whole face is covered by the two palms and gently pressed until the sample is absorbed. During which no other products can be used. For 4 weeks of continuous use, volunteers were analyzed weekly for skin elasticity, skin dermal loss, facial imaging texture wrinkles. Results were recorded at 0, 1, 2, 3, and 4 weeks.
And (3) testing environment: before the test, the face of the volunteer is cleaned by clear water, and the test is carried out after waiting for 30min in the environment with the temperature of 22 +/-2 ℃ and the relative humidity of 50 +/-2% RH.
Testing instruments and indexes: the skin elasticity tester MPA580 (German CK) detects the elasticity index R2 of the face, the average value is taken after 3 times of measurement, the R2 value is the ratio of the rebound quantity of the skin without negative pressure to the maximum stretching quantity with negative pressure, and the closer the R value is to 1, the better the skin elasticity is.
Rate of change% = (R value)After use-R valueBefore use) Value of/RBefore use*100%
TABLE 4 Dermatology of the rate of change of the skin elasticity R2 values
TABLE 5 Rate of change of skin elasticity R2 values people records
As can be seen from tables 4 and 5, in the experimental groups 1 to 3, after the volunteers are used for 4 weeks, the change rate of the skin elasticity R2 is greater than 10%, and the change rate of the skin elasticity R2 of the experimental groups 1 to 3 is faster than that of the blank group and the control group 1 to 8, which indicates that the oil-soluble plant hypecoum extract, the samara extract, the spilanta camara extract and the undaria pinnatifida extract used in the invention have the effects of restoring the skin elasticity and firming the skin.
As can be seen from comparison of experimental groups 1-3 and control groups 1-8, the effect is not satisfactory when one of the oil-soluble extracts of hypsizygus marmoreus, samaria, spilanthes, and undaria is missing or used alone.
2.2 skin transdermal Water loss value (TEWL value) test
Analysis of the skin transepidermal loss TEWL value using a skin water loss meter, TewameterTM300 (CK, Germany) indicates a better skin condition as the TEWL value decreases.
Rate of change% = (TEWL value)After useValue of TEWLBefore use) TEWL valueBefore use*100%
TABLE 6 TEWL variability record for skin dermal loss
TABLE 7 skin transdermal loss TEWL variability record
As can be seen from tables 6 and 7, in the experimental groups 1 to 3, the change rates of TEWL values of volunteers are less than-15% in 4 weeks after the use, and the change rates of the TEWL values of the experimental groups 1 to 3 are faster than those of the blank group and the control group 1 to 8, which shows that the essential oil obtained by compounding the oil-soluble plant hypecoum extract, the samara extract, the spilanta camara extract and the undaria pinnatifida extract has the effect of reducing the water loss of the skin.
2.3 VISIA image analysis wrinkle, texture score test
The face of the volunteer was photographed using the VISIA facial image analysis system (front, left 45 °, right 45 ° directions), and the scores for wrinkles and texture were analyzed, with the lower the score, the less obvious the skin wrinkles and texture.
Rate of change% = (VISIA score)After use-VISIA scoreBefore use) VISIA scoreBefore use*100%
TABLE 8 facial image analysis wrinkle, texture score Change Rate record
TABLE 9 facial image analysis wrinkle, texture score Change Rate record
As can be seen from tables 8 and 9, in the experimental groups 1 to 3, the change rates of the wrinkle value and the texture value of 4 weeks after the use of the oil-soluble plant hypecoum extract, the samara extract, the spilanthes extract and the undaria pinnatifida extract are all less than-15%, and the change rates of the wrinkle value and the texture value of the experimental groups 1 to 3 are faster than those of the blank group and the control group 1 to 8, which indicates that the oil-soluble plant hypecoum extract, the samara extract, the spilantus extract and the undaria pinnatifida extract used in the invention have a synergistic effect, and the compounded essential oil has an effect of reducing wrinkle texture.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention will still fall within the scope of the technical solution of the present invention without departing from the content of the technical solution of the present invention.
Claims (3)
1. The essence oil for resisting aging, wrinkles and firming is characterized by comprising the following components in percentage by weight:
sea fennel extract 0.1-1%
Alarian extract 0.1-1%
Herba Clerodendranthi Spicati extract 0.1-1%
Undaria pinnatifida extract 0.1-1%
Tocopherol acetate 0.1-2%
Caprylic/capric triglyceride 94-99.5%.
2. The essence oil for resisting aging, wrinkles and firming as claimed in claim 1, wherein the essence oil comprises the following components by weight: 0.1% of hypecoum extract, 1% of samaria extract, 0.1% of spilanthes extract, 1% of undaria pinnatifida extract, 95.8% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
3. The essence oil for resisting aging, wrinkles and firming as claimed in claim 1, wherein the essence oil comprises the following components by weight: 0.5% of hypecoum extract, 0.5% of samaria extract, 0.5% of spilanthol extract, 0.5% of undaria pinnatifida extract, 96% of caprylic/capric triglyceride and 2% of tocopheryl acetate.
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| CN110448486B (en) * | 2019-08-14 | 2021-06-11 | 广州睿晞生化科技有限公司 | Essential oil capable of repairing damaged sebum membrane |
| FR3102059B1 (en) * | 2020-12-29 | 2023-12-29 | Algologie | Cosmetic compositions to combat environmental pollution |
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| CN101816624A (en) * | 2010-05-06 | 2010-09-01 | 广州法施兰化妆品有限公司 | Moisturizing cosmetic and preparation method thereof |
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| CN109106651A (en) * | 2018-10-11 | 2019-01-01 | 圣凯西(上海)生物科技有限公司 | A kind of compact frost of anti-wrinkle and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| FR3027228B1 (en) * | 2014-10-20 | 2016-12-09 | Valbiotis | COMPOSITION COMPRISING A MIXTURE OF PLANT EXTRACTS AND USE FOR ACTING ON GLUCIDIC AND / OR LIPID METABOLISM |
| US10512603B2 (en) * | 2015-03-05 | 2019-12-24 | Lubrizol Advanced Materials, Inc. | Ferment extract of Eupenicillium crustaceum and cosmetic use thereof |
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| CN101816624A (en) * | 2010-05-06 | 2010-09-01 | 广州法施兰化妆品有限公司 | Moisturizing cosmetic and preparation method thereof |
| CN107334725A (en) * | 2017-08-08 | 2017-11-10 | 广州蜜妆生物科技有限公司 | A kind of anti-ageing American's flesh facial mask of Crithmum maritimum |
| CN107468582A (en) * | 2017-09-12 | 2017-12-15 | 上海馥优化妆品有限公司 | One kind is compacted anti-wrinkle eye shadow and preparation method thereof |
| CN108853000A (en) * | 2018-08-17 | 2018-11-23 | 广州皓雨投资有限公司 | Have effects that moisture-keeping crease-shedding restores the composition of elasticity of skin, facial mask and preparation method thereof |
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