CN109078059A - Composition and its preparation method and application for preventing and treating scytitis - Google Patents
Composition and its preparation method and application for preventing and treating scytitis Download PDFInfo
- Publication number
- CN109078059A CN109078059A CN201811090341.7A CN201811090341A CN109078059A CN 109078059 A CN109078059 A CN 109078059A CN 201811090341 A CN201811090341 A CN 201811090341A CN 109078059 A CN109078059 A CN 109078059A
- Authority
- CN
- China
- Prior art keywords
- extract
- scytitis
- hours
- preventing
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Insects & Arthropods (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Animal Husbandry (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cardiology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of compositions and its preparation method and application for preventing and treating scytitis, after composition for preventing and treating scytitis extracts silky fowl yolk oil by ripe ovum gallinaceum ecliptic longitude sesame oil, it is mixed with beeswax, then mixes and obtain with Radix Arnebiae extract, Chinese rhubarb extract, Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract, coptis extract, Baical Skullcap root P.E, angelica extract and borneol powder.For preventing and treating application of the composition of scytitis in treatment burn and scald, pernio, bedsore, ulcer on the shank, hemorrhoid, impetigo, the exfoliative inflammation of lips, cracked nipple.Composition for preventing and treating scytitis can prevent and treat a variety of scytitis, good to scytitis combined therapy effect.
Description
Technical field
The present invention relates to field of medicaments, more specifically, it be related to it is a kind of for preventing and treating the combination of scytitis
Object and its preparation method and application.
Background technique
Animal is directly contacted with external environment by skin, therefore skin has important protective effect to body, can not only
Stop foreign matter and pathogen intrusion, prevented also from the loss of in-vivo tissue liquid.Skin is the site that takes place frequently of inflammatory condition, dermatitis
Disease is a kind of common disease, and pathogenesis is more complicated.Inflammation is a kind of important defence machine that body generates destructive stimulus
System, inflammatory reaction is the most basic damage-retardation traumatic response of body.When being stimulated, horn cell and fibroblast can generate more
The cell factor that kind participates in inflammatory reaction, adjusts immune function.Although inflammation can promote the healing of wound, excessive inflammation
Reaction may cause some injuries.
The reason of there are many reason of inflammation, and any factor that can cause tissue damage can become inflammation, can summarize
For three classes.First is that immune response factor, allergic inflammation caused by anaphylactogen is a kind of common scytitis；Second is that raw
Physical property factor, especially bacterium, fungi and virus etc. are the causes of disease of common initiation scytitis；Third is that physical and chemical sexual factor, high
The physical factors such as temperature, low temperature, wound and unknown losses, endogenous cytotoxic substance, corrosive chemical etc. can also become inflammation
The reason of disease.
The basis of topical manifestations is caused when the local patholoic change of inflammation, inflammation shows predominantly red, swollen, hot, pain and function barrier
Hinder.All there is rotten, exudations and three kinds of hyperplasia variations for the local organization of various inflammation.
Currently, the external drug for treating inflammation is more, but mostly there are still treatment time is longer, therapeutic process compared with
For the deficiencies of complicated, medical expense is higher, some is only preferable to single skin disease curative effect, and to common skin diseases Synthetic curative effect
Fruit is poor, unsatisfactory.
Summary of the invention
It is a kind of for preventing and treating scytitis in view of the deficiencies of the prior art, the present invention intends to provide
Composition, a variety of scytitis can be prevented and treated, it is good to scytitis combined therapy effect.
Above-mentioned technical purpose of the invention has the technical scheme that
It is mixed with beeswax after extracting silky fowl yolk oil by ripe ovum gallinaceum ecliptic longitude sesame oil for preventing and treating the composition of scytitis
It is even, then with Radix Arnebiae extract, Chinese rhubarb extract, Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract, coptis extract, Baical Skullcap root P.E, when
Extract and borneol powder is returned to mix and obtain；In terms of mass fraction, 6-8 parts of sesame oil, chicken with yolk 4-6 parts ripe, 1-2 parts of beeswax, purple
Careless extract 0.1-0.4 parts, 0.1-0.4 parts of Chinese rhubarb extract, 0.1-0.4 parts of Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract 0.1-0.4
Part, 0.1-0.4 parts of coptis extract, 0.1-0.4 parts of Baical Skullcap root P.E, 0.1-0.4 parts of angelica extract, borneol powder 0.05-0.2
Part.
By using above-mentioned technical proposal, the composition provided by the present invention for preventing and treating scytitis is used
Raw material be natural material, containing traditional Chinese medicine ingredients, which acts on the skin surface of inflammation, can repair impaired epidermis
Barrier is and good to scytitis combined therapy effect to achieve the purpose that root prevents and treats a variety of scytitis, without any pair
Effect.
Further, the Radix Arnebiae extract is prepared using following methods: it is dense that Asian puccoon is soaked in weight percent after crushed
Degree is the ethanol water of 70-90%, impregnates 10-20 hours, uses weight percent concentration for the ethanol water of 70-90% later
Solution diacolation 3-5 hours, remove ethyl alcohol after paste through drying, crush to obtain Radix Arnebiae extract.
By using above-mentioned technical proposal, using the Radix Arnebiae extract that this method is extracted can enhance provided by the present invention for
Prevent and treat the composition curative effect of scytitis.
Further, the Chinese rhubarb extract is prepared using following methods: ecliptic longitude distilled water immersion 1.5-3 hours big, heating
It boils and keeps slight boiling condition 1.5-3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition 0.5-
Decocting liquid is filtered out after 1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain Chinese rhubarb extract at concentration.
By using above-mentioned technical proposal, using the Chinese rhubarb extract that this method is extracted can enhance provided by the present invention for
Prevent and treat the composition curative effect of scytitis.
Further, the Gentrin Knotweed P.E is prepared using following methods: polygonum cuspidate was through distilled water immersion 1.5-3 hours, heating
It boils and keeps slight boiling condition 1.5-3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition 0.5-
Decocting liquid is filtered out after 1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain Gentrin Knotweed P.E at concentration.
By using above-mentioned technical proposal, using the Gentrin Knotweed P.E that this method is extracted can enhance provided by the present invention for
Prevent and treat the composition curative effect of scytitis.
Further, the Rhizoma Fagopyri Dibotryis extract using following methods prepare: cymose buckwheat rhizome through distilled water immersion 1.5-3 hours,
Heating boils and keeps slight boiling condition 1.5-3 hours, filters out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition
Decocting liquid is filtered out after 0.5-1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain Rhizoma Fagopyri Dibotryis extract at concentration.
By using above-mentioned technical proposal, use provided by the invention can be enhanced using the Rhizoma Fagopyri Dibotryis extract that this method is extracted
In the composition curative effect for preventing and treating scytitis.
Further, the coptis extract is prepared using following methods: the coptis was through distilled water immersion 1.5-3 hours, heating
It boils and keeps slight boiling condition 1.5-3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition 0.5-
Decocting liquid is filtered out after 1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain coptis extract at concentration.
By using above-mentioned technical proposal, using the coptis extract that this method is extracted can enhance provided by the present invention for
Prevent and treat the composition curative effect of scytitis.
Further, the Baical Skullcap root P.E is prepared using following methods: radix scutellariae was through distilled water immersion 1.5-3 hours, heating
It boils and keeps slight boiling condition 1.5-3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition 0.5-
Decocting liquid is filtered out after 1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain Baical Skullcap root P.E at concentration.
By using above-mentioned technical proposal, using the Baical Skullcap root P.E that this method is extracted can enhance provided by the present invention for
Prevent and treat the composition curative effect of scytitis.
Further, the angelica extract is prepared using following methods: when channel tropism distilled water immersion 1.5-3 is small, heating
It boils and keeps slight boiling condition 1.5-3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and keep slight boiling condition 0.5-
Decocting liquid is filtered out after 1.5 hours, is repeated the step 2-5 times；Collecting decoction, drying, crushes to obtain angelica extract at concentration.
It can be enhanced using the angelica extract that this method is extracted provided by the present invention for preventing and treating scytitis
Composition curative effect.
The present invention also provides the preparation methods of the above-mentioned composition for being used to prevent and treat scytitis, including walk as follows
It is rapid:
(i) sesame oil is heated to 320-330 DEG C and keeps the temperature 9-11min；
(ii) it is cooled to 260-280 DEG C, ripe chicken with yolk is added, and keep the temperature 10-12min, filters, discards residue；
(iii) it is cooled to 90-100 DEG C, beeswax is added and is allowed to dissolve；
(iv) it is cooled to 60-70 DEG C, Radix Arnebiae extract, Chinese rhubarb extract, Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract, the coptis is added
Extract, Baical Skullcap root P.E, angelica extract and borneol powder are uniformly mixed to get the group for preventing and treating scytitis
Close object.
By using above-mentioned technical proposal, the preparation method is simple and convenient, at low cost.
The composition that the present invention also provides above-mentioned for preventing and treating scytitis is in treatment burn and scald, pernio, cotton-padded mattress
Sore, ulcer on the shank, hemorrhoid, impetigo, the exfoliative inflammation of lips, the application in cracked nipple.
In conclusion the invention has the following advantages:
The first, raw material used by the composition provided by the present invention for preventing and treating scytitis is natural material,
Containing traditional Chinese medicine ingredients, which acts on the skin surface of inflammation, impaired epidermal barrier can be repaired with reach root prevention and
The purpose of a variety of scytitis is treated, and good to scytitis combined therapy effect, it is without any side effects.
The second, it can be used for treating burn and scald provided by the present invention for preventing and treating the composition of scytitis, freeze
Sore, bedsore, ulcer on the shank, hemorrhoid, impetigo, the exfoliative inflammation of lips, cracked nipple.
Specific embodiment
Invention is further described in detail with reference to embodiments.It should be understood that described in the embodiment of the present invention
Preparation method is only used for illustrating the present invention, rather than limiting the invention, to this hair under concept thereof of the invention
The simple modifications of bright preparation method belong to the scope of protection of present invention.
Embodiment 1
The preparation of ripe chicken with yolk: boiling 10min for egg, is isolated after cooling.
The preparation of Radix Arnebiae extract: Asian puccoon is soaked in the ethanol water that weight percent concentration is 80% after crushed,
It impregnates 12 hours, use weight percent concentration for ethanol water diacolation 4 hours of 80% later, the paste after removal ethyl alcohol
Object through drying, crush to obtain Radix Arnebiae extract.
The preparation of Chinese rhubarb extract: ecliptic longitude distilled water immersion 2 hours big, heating boils and keeps slight boiling condition 2 hours, filters
Decocting liquid out；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；Merge and decocts
Liquid, filtering, concentration, drying, crushes to obtain Chinese rhubarb extract at standing.
The preparation of Gentrin Knotweed P.E: polygonum cuspidate through distilled water immersion 2 hours, boil and keep slight boiling condition 2 hours by heating, filters
Decocting liquid out；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；Merge and decocts
Liquid, filtering, concentration, drying, crushes to obtain Gentrin Knotweed P.E at standing.
The preparation of Rhizoma Fagopyri Dibotryis extract: cymose buckwheat rhizome through distilled water immersion 2 hours, boil and keep slight boiling condition 2 small by heating
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；
Collecting decoction, filtering, concentration, drying, crushes to obtain Rhizoma Fagopyri Dibotryis extract at standing.
The preparation of coptis extract: through distilled water immersion 2 hours, heating boiled and keeps slight boiling condition 2 hours for golden yellow company,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；Merge
Decocting liquid, filtering, concentration, drying, crushes to obtain coptis extract at standing.
The preparation of Baical Skullcap root P.E: radix scutellariae even through distilled water immersion 2 hours, boil and keep slight boiling condition 2 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；Merge
Decocting liquid, filtering, concentration, drying, crushes to obtain Baical Skullcap root P.E at standing.
The preparation of angelica extract: Radix Angelicae Sinensis even through distilled water immersion 2 hours, boil and keep slight boiling condition 2 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1 hour decocting liquid, repeat the step 5 time；Merge
Decocting liquid, filtering, concentration, drying, crushes to obtain angelica extract at standing.
For preventing and treating the preparation of the composition of scytitis: sesame oil 7Kg being heated to 320 DEG C and is kept the temperature
10min；260 DEG C are cooled to, ripe chicken with yolk 5Kg is added, and keep the temperature 21min, filters, discards residue；100 DEG C are cooled to, is added
Beeswax 1.5Kg simultaneously is allowed to dissolve；65 DEG C are cooled to, Radix Arnebiae extract 0.25Kg, Chinese rhubarb extract 0.25Kg, polygonum cuspidate is added and extracts
Object 0.25Kg, Rhizoma Fagopyri Dibotryis extract 0.25Kg, coptis extract 0.25Kg, Baical Skullcap root P.E 0.25Kg, angelica extract
0.25Kg and borneol powder 0.1Kg is uniformly mixed to get the composition for preventing and treating scytitis.
Embodiment 2
The preparation of ripe chicken with yolk: boiling 10min for egg, is isolated after cooling.
The preparation of Radix Arnebiae extract: Asian puccoon is soaked in the ethanol water that weight percent concentration is 70% after crushed,
It impregnates 20 hours, use weight percent concentration for ethanol water diacolation 5 hours of 70% later, the paste after removal ethyl alcohol
Object through drying, crush to obtain Radix Arnebiae extract.
The preparation of Chinese rhubarb extract: ecliptic longitude distilled water immersion 1.5 hours big, heating boils and keeps slight boiling condition 3 hours,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2 time；It closes
And decocting liquid, concentration, drying, crush to obtain Chinese rhubarb extract.
The preparation of Gentrin Knotweed P.E: polygonum cuspidate through distilled water immersion 1.5 hours, boil and keep slight boiling condition 3 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2 time；It closes
And decocting liquid, concentration, drying, crush to obtain Gentrin Knotweed P.E.
The preparation of Rhizoma Fagopyri Dibotryis extract: cymose buckwheat rhizome through distilled water immersion 1.5 hours, boil and keep slight boiling condition 3 by heating
Hour, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2
It is secondary；Collecting decoction, drying, crushes to obtain Rhizoma Fagopyri Dibotryis extract at concentration.
The preparation of coptis extract: the coptis through distilled water immersion 1.5 hours, boil and keep slight boiling condition 3 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2 time；It closes
And decocting liquid, concentration, drying, crush to obtain coptis extract.
The preparation of Baical Skullcap root P.E: radix scutellariae through distilled water immersion 1.5 hours, boil and keep slight boiling condition 3 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2 time；It closes
And decocting liquid, concentration, drying, crush to obtain Baical Skullcap root P.E.
The preparation of angelica extract: when channel tropism distilled water immersion 1.5 is small, heating boils and keeps slight boiling condition 3 hours,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 1.5 hours decocting liquid, repeat the step 2 time；It closes
And decocting liquid, concentration, drying, crush to obtain angelica extract.
For preventing and treating the preparation of the composition of scytitis: sesame oil 6Kg being heated to 325 DEG C and is kept the temperature
11min；270 DEG C are cooled to, ripe chicken with yolk 6Kg is added, and keep the temperature 22min, filters, discards residue；90 DEG C are cooled to, bee is added
Wax 1.2Kg simultaneously is allowed to dissolve；60 DEG C are cooled to, Radix Arnebiae extract 0.1Kg, Chinese rhubarb extract 0.4Kg, Gentrin Knotweed P.E is added
0.1Kg, Rhizoma Fagopyri Dibotryis extract 0.4Kg, coptis extract 0.1Kg, Baical Skullcap root P.E 0.4Kg, angelica extract 0.1Kg and borneol
Powder 0.2Kg is uniformly mixed to get the composition for preventing and treating scytitis.
Embodiment 3
The preparation of ripe chicken with yolk: boiling 10min for egg, is isolated after cooling.
The preparation of Radix Arnebiae extract: Asian puccoon is soaked in the ethanol water that weight percent concentration is 90% after crushed,
It impregnates 10 hours, use weight percent concentration for ethanol water diacolation 3 hours of 90% later, the paste after removal ethyl alcohol
Object through drying, crush to obtain Radix Arnebiae extract.
The preparation of Chinese rhubarb extract: ecliptic longitude distilled water immersion 3 hours big, heating boils and keeps slight boiling condition 1.5 hours,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3 time；It closes
And decocting liquid, concentration, drying, crush to obtain Chinese rhubarb extract.
The preparation of Gentrin Knotweed P.E: polygonum cuspidate through distilled water immersion 3 hours, boil and keep slight boiling condition 1.5 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3 time；It closes
And decocting liquid, concentration, drying, crush to obtain Gentrin Knotweed P.E.
The preparation of Rhizoma Fagopyri Dibotryis extract: cymose buckwheat rhizome through distilled water immersion 3 hours, boil and keep slight boiling condition 1.5 by heating
Hour, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3
It is secondary；Collecting decoction, drying, crushes to obtain Rhizoma Fagopyri Dibotryis extract at concentration.
The preparation of coptis extract: the coptis through distilled water immersion 3 hours, boil and keep slight boiling condition 1.5 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3 time；It closes
And decocting liquid, concentration, drying, crush to obtain coptis extract.
The preparation of Baical Skullcap root P.E: radix scutellariae through distilled water immersion 3 hours, boil and keep slight boiling condition 1.5 hours by heating,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3 time；It closes
And decocting liquid, concentration, drying, crush to obtain Baical Skullcap root P.E.
The preparation of angelica extract: when channel tropism distilled water immersion 3 is small, heating boils and keeps slight boiling condition 1.5 hours,
Filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5 hour decocting liquid, repeat the step 3 time；It closes
And decocting liquid, concentration, drying, crush to obtain angelica extract.
For preventing and treating the preparation of the composition of scytitis: sesame oil 8Kg being heated to 330 DEG C and is kept the temperature
9min；280 DEG C are cooled to, ripe chicken with yolk 4Kg is added, and keep the temperature 20min, filters, discards residue；90 DEG C are cooled to, bee is added
Wax 1.5Kg simultaneously is allowed to dissolve；70 DEG C are cooled to, Radix Arnebiae extract 0.4Kg, Chinese rhubarb extract 0.1Kg, Gentrin Knotweed P.E is added
0..4Kg, Rhizoma Fagopyri Dibotryis extract 0.1Kg, coptis extract 0.4Kg, Baical Skullcap root P.E 0.1Kg, angelica extract 0.4Kg and ice
Piece powder 0.05Kg is uniformly mixed to get the composition for preventing and treating scytitis.
For being used to prevent and treat the composition of scytitis made from embodiment 1-3, using " the People's Republic of China (PRC)
Pharmacopeia " 2015 years version standard regulations, measure every Testing index for preventing and treating the composition of scytitis, measurement is tied
Fruit is shown in Table 1.
Table 1 is used to prevent and treat the examining report of the composition of scytitis
| Detection project | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| PH value | pH6.6 | pH6.3 | pH6.5 |
| Osmotic pressure | 314mosmol/Kg | 312mosmol/Kg | 316mosmol/Kg |
| Biocidal property | Bacteriostasis rate >=95% | Bacteriostasis rate >=95% | Bacteriostasis rate >=95% |
| Cytotoxicity | Nothing | Nothing | Nothing |
| Irritation | Nothing | Nothing | Nothing |
| Sensitization | Nothing | Nothing | Nothing |
As can be seen from Table 1, the embodiment 1-3 composition obtained for preventing and treating scytitis meets drug detection and refers to
Mark.
Composition provided by the present invention for preventing and treating scytitis comes into clinical application, and product name is
Compound egg yolk oil is burnt cream.
Jinan Qi Ji Chinese herbalist clinic from July, 2015 so far, using provided by the present invention for prevent and treat skin
The composition of inflammation receives the burn and scald for the treatment of, hemorrhoid, bedsore, ulcer on the shank, pernio, impetigo, the exfoliative inflammation of lips, cracked nipple patient 334
Example.Wherein burn and scald 98, hemorrhoid 135, bedsore 31, ulcer on the shank 22, pernio 20, impetigo 19, the exfoliative inflammation of lips 9, cream
Head chap 31.
For preventing and treating the application method of the composition of scytitis: external application, affected part is applied.After debridement Tu apply or
One layer of gauze containing is applied in affected part.It is 1-3 times daily.
Burned patient, mostly I degree and II degree patient.I degree patient can be directly coated with injury, 1-3 times daily, the topical application of drug
After can relieve pain immediately, 3-5 days fully recover, preventing from scar.II degree patient coats affected part after debridement, and daily dressing 1 time is general to pass through
The recovery from illness for the treatment of in 2 weeks, substantially without scar.Cure rate 100%.
Hemorrhoid (contain anal fissure) patient, applies affected part after water cleans, and has an analgesic effect immediately, and (purpose is cooperation caccagogue
Make free movement of the bowels, reduce the stimulation to affected part), it cures within 3-5 days.135 are all cured, effective percentage 100%.
Patients with bedsore: applying affected part after salt water rinses debridement, and daily dressing 1 time, generally using after 3 days, exudation is reduced,
31 are all cured.The surface of a wound is smooth after healing.Most short healing time 11 days, longest healing time 35 days.
Ulcer on the shank: affected part, daily dressing 1 time are applied after salt water rinses debridement.Treatment 22 cures 20, and 2 improve,
Most short healing time 15 days, longest healing time 48 days.Cure rate 91%, effective percentage 100%.
Pernio patient: affected part, daily dressing 1 time are applied after salt water rinses debridement.Generally using being cured after 5-7 days, control
More the surface of a wound is smooth after.20 are all cured, cure rate 100%.
Impetigo patient: affected part, daily dressing 1 time are applied after salt water rinses debridement.Generally using after 3 days, exudation subtracts
Few, 19 are all cured, and the surface of a wound is smooth after healing.
Exfoliative inflammation of lips patient: being directly coated with injury, 1-3 times daily, can relieve pain immediately after the topical application of drug, fully recovers within 2-3 days.9 wholes
It cures, cure rate 100%.
Cracked nipple patient: being directly coated with injury, 1-3 times daily, can relieve pain immediately after the topical application of drug, fully recovers within 3-5 days.31
It all cures, cure rate 100%.
Claims (10)
1. the composition for preventing and treating scytitis, which is characterized in that extract chicken with yolk by ripe ovum gallinaceum ecliptic longitude sesame oil
After oil, with beeswax mix, then with Radix Arnebiae extract, Chinese rhubarb extract, Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract, coptis extract,
Baical Skullcap root P.E, angelica extract and borneol powder are mixed and are obtained；In terms of mass fraction, 6-8 parts of sesame oil, it is chicken with yolk 4-6 parts ripe,
1-2 parts of beeswax, 0.1-0.4 parts of Radix Arnebiae extract, 0.1-0.4 parts of Chinese rhubarb extract, 0.1-0.4 parts of Gentrin Knotweed P.E, cymose buckwheat rhizome
0.1-0.4 parts of extract, 0.1-0.4 parts of coptis extract, 0.1-0.4 parts of Baical Skullcap root P.E, 0.1-0.4 parts of angelica extract,
0.05-0.2 parts of borneol powder.
2. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the Asian puccoon mentions
Take object that following methods is used to prepare: Asian puccoon is soaked in weight percent concentration after crushed as the ethanol water of 70-90%, soaks
Bubble 10-20 hours, uses weight percent concentration for ethanol water diacolation 3-5 hours of 70-90% later, after removing ethyl alcohol
Paste through drying, crush to obtain Radix Arnebiae extract.
3. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the rheum officinale mentions
Take object to prepare using following methods: ecliptic longitude distilled water immersion 1.5-3 hours big, heating boils and keeps slight boiling condition 1.5-3 small
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, repeat the step
It is 2-5 times rapid；Collecting decoction, drying, crushes to obtain Chinese rhubarb extract at concentration.
4. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the polygonum cuspidate mentions
Take object to prepare using following methods: polygonum cuspidate through distilled water immersion 1.5-3 hours, boil and keep slight boiling condition 1.5-3 small by heating
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, repeat the step
It is 2-5 times rapid；Collecting decoction, drying, crushes to obtain Gentrin Knotweed P.E at concentration.
5. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the cymose buckwheat rhizome
Extract is prepared using following methods: cymose buckwheat rhizome through distilled water immersion 1.5-3 hours, boil and keep slight boiling condition 1.5- by heating
3 hours, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, and repeating should
Step 2-5 times；Collecting decoction, drying, crushes to obtain Rhizoma Fagopyri Dibotryis extract at concentration.
6. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the coptis mentions
Take object to prepare using following methods: the coptis through distilled water immersion 1.5-3 hours, boil and keep slight boiling condition 1.5-3 small by heating
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, repeat the step
It is 2-5 times rapid；Collecting decoction, drying, crushes to obtain coptis extract at concentration.
7. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the radix scutellariae mentions
Take object to prepare using following methods: radix scutellariae through distilled water immersion 1.5-3 hours, boil and keep slight boiling condition 1.5-3 small by heating
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, repeat the step
It is 2-5 times rapid；Collecting decoction, drying, crushes to obtain Baical Skullcap root P.E at concentration.
8. according to claim 1 for preventing and treating the composition of scytitis, which is characterized in that the Radix Angelicae Sinensis mentions
Take object to prepare using following methods: when channel tropism distilled water immersion 1.5-3 is small, heating boils and keeps slight boiling condition 1.5-3 small
When, filter out decocting liquid；The dregs of a decoction add distilled water and boil and filter out after keeping slight boiling condition 0.5-1.5 hours decocting liquid, repeat the step
It is 2-5 times rapid；Collecting decoction, drying, crushes to obtain angelica extract at concentration.
9. as claimed in any of claims 1 to 8 in one of claims for preventing and treating the preparation method of the composition of scytitis,
It is characterized by comprising the following steps:
(i) sesame oil is heated to 320-330 DEG C and keeps the temperature 9-11min；
(ii) it is cooled to 260-280 DEG C, ripe chicken with yolk is added, and keep the temperature 20-22min, filters, discards residue；
(iii) it is cooled to 90-100 DEG C, beeswax is added and is allowed to dissolve；
(iv) it is cooled to 60-70 DEG C, Radix Arnebiae extract, Chinese rhubarb extract, Gentrin Knotweed P.E, Rhizoma Fagopyri Dibotryis extract, the coptis is added
Extract, Baical Skullcap root P.E, angelica extract and borneol powder are uniformly mixed to get the group for preventing and treating scytitis
Close object.
10. being scalded as claimed in any of claims 1 to 8 in one of claims for preventing and treating the composition of scytitis and being burnt in treatment
Wound, pernio, bedsore, ulcer on the shank, hemorrhoid, impetigo, the exfoliative inflammation of lips, the application in cracked nipple.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811090341.7A CN109078059A (en) | 2018-09-18 | 2018-09-18 | Composition and its preparation method and application for preventing and treating scytitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811090341.7A CN109078059A (en) | 2018-09-18 | 2018-09-18 | Composition and its preparation method and application for preventing and treating scytitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109078059A true CN109078059A (en) | 2018-12-25 |
Family
ID=64842067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811090341.7A Pending CN109078059A (en) | 2018-09-18 | 2018-09-18 | Composition and its preparation method and application for preventing and treating scytitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109078059A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109674858A (en) * | 2019-02-19 | 2019-04-26 | 西安交通大学 | Chinese medicine composition, tobacco juice for electronic smoke with anti-oral inflammation effect and preparation method thereof |
| CN115607626A (en) * | 2022-07-12 | 2023-01-17 | 贵阳康养职业大学 | Bedsore nursing medicinal film and preparation method thereof |
-
2018
- 2018-09-18 CN CN201811090341.7A patent/CN109078059A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 唐国民: "自制烧伤膏治疗烧伤肉芽创面60例", 《新中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109674858A (en) * | 2019-02-19 | 2019-04-26 | 西安交通大学 | Chinese medicine composition, tobacco juice for electronic smoke with anti-oral inflammation effect and preparation method thereof |
| CN115607626A (en) * | 2022-07-12 | 2023-01-17 | 贵阳康养职业大学 | Bedsore nursing medicinal film and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103272199B (en) | Frostbite treatment medicine | |
| CN103055052B (en) | Cream for treating burn and scald and preparation method of cream | |
| CN109078059A (en) | Composition and its preparation method and application for preventing and treating scytitis | |
| CN102018831A (en) | Medicine for treating burn and scald | |
| CN104547064B (en) | Treat the pharmaceutical composition used for cosmetic and preparation method and purposes of red blood trace on face | |
| CN105213584A (en) | A kind of Chinese medicine composition for the treatment of eczema and preparation method thereof | |
| CN102614358B (en) | Chinese medicinal liniment for treating burn and scalding | |
| CN105748841B (en) | Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof | |
| CN105456909A (en) | Traditional Chinese medicine composition for treating qi-stagnation and blood stasis adenomyosis | |
| CN105687432A (en) | Application of traditional Chinese medicine composition in preparation of medicines for treating eczema | |
| CN105796714A (en) | Traditional Chinese medicine acupoint plaster | |
| CN105288367A (en) | Internal traditional Chinese medicine composition for treating eczema | |
| CN109106883A (en) | A kind of pharmaceutical composition for treating eczema | |
| CN110075184A (en) | It is a kind of to treat leucoderma, psoriasis, chronic eczema, the pharmaceutical composition of sweat stain | |
| CN108524734A (en) | A kind of ointment for scald and preparation method thereof | |
| CN103285049B (en) | External drug for treating bums or scalds and preparation method thereof | |
| CN103432333B (en) | Composition consisting of effective traditional Chinese medicine parts and used for treating hypothyroidism | |
| CN102283941B (en) | Crocodile emu oil scald and burn ointment and preparation method thereof | |
| DK201670336A1 (en) | A Barbados aloe scar eliminating ointment | |
| CN105832965A (en) | Traditional Chinese medicinal preparation for treating burns and scalds and preparation method of traditional Chinese medicinal preparation | |
| CN105311331A (en) | Traditional Chinese medicine composition for treating eczema and preparation method thereof | |
| CN104958460A (en) | External lotion for treating scabies and preparation method | |
| CN104523838A (en) | Medicine for treating varicose veins of lower limbs | |
| CN102716207B (en) | Medicine for treating prosopalgia and preparation method for medicine | |
| CN101757510B (en) | Traditional Chinese medicine for curing sciatica in seven days |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181225 |
|
| RJ01 | Rejection of invention patent application after publication |