A kind of Chinese medicinal effective-part composition for the treatment of hypothyroidism
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition being used for the treatment of hypothyroidism.
Background technology
Hypothyroidism, being called for short hypothyroidism, is owing to lacking thyroxin in blood circulation, the disease that internal metabolism process lowers and causes.Any age can be occurred in, have different names of disease with the difference of age of onset, as cretinism, childhood hypothyroidism, adult's hypothyroidism.Be called that the general of hypothyroidism refers to the latter more clinically.According to external investigation report, the overall incidence of men and women accounts for 0.1% and 1.9% respectively, and women is obviously more than male.Its cause of disease can be divided into constitutional and Secondary cases two class, is secondary to thyroidectomy in recent years or iodine therapy person is in the majority.Hypothyroidism is obstinate disease, and current modern Western medicine is still based on alternative medicine, and still difficulty is effected a radical cure, and many side effect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation for the treatment of hypothyroidism, this active component composition can treat hypothyroidism, and not easily recurs.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
Hypothyroidism belongs to the asthenia of the traditional Chinese medical science or deficient category.Innate deficiency, lack of proper care after one's birth, the weak or prolonged illness of body constitution loses and controls, the factors such as internal injury of being overworked for a very long period all can cause internal organs hypofunction, insufficiency of generating and transforming QI and blood.Its main pathogenesis is weakened body resistance, relates to kidney, spleen and the heart three dirty, and has the performance that part expectorant is turbid.
Treat a Chinese medicinal effective-part composition for hypothyroidism, be made up of the following raw material according to mass fraction meter: Rhizoma Dioscoreae Bulbiferae 22, Herba Typhonii gigantei 25, Herba Polygalae Japonicae 19, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 18, Radix Flemingiae Philippinensis 12 and Semen Momordicae 4.
The preparation method of Chinese medicinal effective-part composition of the present invention is that add 12 times of water gagings, boil with high heat, change slow fire boiling into 2 hours, waste, to obtain final product by above-mentioned raw materials compositions according to proportioning combination drying.
Compared with prior art, the present invention has following beneficial effect:
Find through experiment, the Chinese medicinal effective-part composition made according to proportioning of the present invention has warming the kidney to activate YANG, QI invigorating cold relieving, the effect that nourshing Yin and drynsessmoistening prescription, spleen invigorating helps fortune, Qiangxin Fumai, softening the hard mass dampness removing, may be used for treating hypothyroidism, not easily recur after healing.
Detailed description of the invention
Explain the present invention further below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Rhizoma Dioscoreae Bulbiferae 22g, Herba Typhonii gigantei 25g, Herba Polygalae Japonicae 19g, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 18g, Radix Flemingiae Philippinensis 12g and Semen Momordicae 4g, add 12 times of water gagings after drying, after boiling with intense fire, then use slow fire decocting 120min, gained decoction is for subsequent use.
embodiment 2
Clinical observation hypothyroidism patient 200.Patient is all diagnosed as hypothyroidism through clinical diagnosis.Embodiment 1 gained decoction is taken, 2 times on the 1st to patient, sooner or later bfore meals, continuous 15 days.
The patient census taking embodiment 1 gained decoction the results are shown in Table 1.Effective comprising in table 1 cures and effectively, wherein, cures and refer to that clinical symptoms disappears substantially, and laboratory indexes recovers normal or normal; Effectively refer to that clinical symptoms makes moderate progress, especially asthenic cold type symptom is obviously improved, and laboratory indexes takes a turn for the better, and T3, T4, FT4/FT9 increase to some extent, and TSH declines to some extent, but not yet reach normal level.Invalidly refer to that clinical symptoms and sign are without improvement or improve not obvious.
Table 1
Number of cases |
Effective |
Invalid |
Obvious effective rate (%) |
200 |
189 |
11 |
94.5 |
Known by above-mentioned data, after decoction made by Chinese medicine of the present invention, can in 15 days the treatment hypothyroidism of highly significant.
embodiment 3
Use the decoction administration ICR mice that embodiment 1 is obtained, body weight 20 ~ 25g, male and female half and half, successive administration 60d.
Through prerun, the decoction toxicity that embodiment 1 obtains is very low, does not measure LD50, therefore carries out maximum dosage-feeding mensuration on the one to mice.Maximum dosage-feeding is 400ml/d, observes none example and be poisoned to death after 60 days, and all healthy survival, proves that the decoction that compositions of the present invention is made can not toxic side effect to human body thus.