A kind of Chinese medicinal effective-part composition for the treatment of diabetes insipidus
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to a kind of Chinese medicinal effective-part composition that is used for the treatment of diabetes insipidus.
Background technology
Diabetes insipidus is to urinate the endocrinopathy as Clinical symptoms taking excessive thirst, polyuria, low-gravity.Diabetes insipidus that it has been established that is with due to antidiuretic hormone secretion deficiency, but also can be because kidney causes vassopressin reaction defect, and the former is called central or pituitary diabetes insipidus, and the latter is called nephrogenic diabetes insipidus.Clinical separately with diabetes insipidus name, mainly refer to pituitary diabetes insipidus, taking middle-aged male as common.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal effective-part composition for the preparation for the treatment of diabetes insipidus, this active component composition can be treated diabetes insipidus, and is difficult for recurrence.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The traditional Chinese medical science, about the cause of disease of diabetes insipidus, there is no monograph so far, through concluding, substantially has innate deficiency, eating and drinking without temperance, and feelings will is not smooth, and tumbling down injures exopathogen outward and the factor such as invades outward.
Treat a Chinese medicinal effective-part composition for diabetes insipidus, by making according to the raw material of mass fraction meter as follows: Bulbus Allii Fistulosi 26, phragmites communis 21, Caulis Erycibes 19, Flos Daturae 16, Semen Hydnocarpi 15 and Herba Cistanches 3.
The preparation method of Chinese medicinal effective-part composition of the present invention be by above-mentioned raw materials compositions according to proportioning combination drying, add 15 times of water gagings, boil with high heat, change slow fire boiling into 2 hours, waste, to obtain final product.
Compared with prior art, the present invention has following beneficial effect:
Find through experiment, the Chinese medicinal effective-part composition of making according to proportioning of the present invention has nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, warming YANG and invigorating QI, tonifying the kidney to reduce urination, spleen invigorating and helps fortune, the astringent or styptic treatment for spontaneous sweating effect of the kidney invigorating, not only can be used for the treatment of diabetes insipidus, after curing, is difficult for recurring.
Detailed description of the invention
Further explain the present invention below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
embodiment 1
Bulbus Allii Fistulosi 26g, phragmites communis 21g, Caulis Erycibes 19g, Flos Daturae 16g, Semen Hydnocarpi 15g and Herba Cistanches 3g, add 15 times of water gagings after being dried, and after boiling, then uses slow fire decocting 120min with intense fire, and gained decoction is for subsequent use.
embodiment 2
500 of clinical observation diabetes insipidus patients.Patient is all diagnosed as diabetes insipidus through clinical diagnosis.Take embodiment 1 gained decoction to patient, 2 times on the 1st, sooner or later bfore meals, continuous 10 days.
Take patient's statistical result of embodiment 1 gained decoction in table 1.Cure and effectively, wherein, cure and refer to clinical symptom disappearance effective the comprising in table 1, and specific gravity of urine is normal; Effectively refer to that polydipsia, polyuria symptom obviously improve, amount of drinking water and urine amount all reduce over half, but not yet recover normal, specific gravity of urine raise approach normal.Invalidly refer to that clinical symptoms makes moderate progress or improves not obvious or increase the weight of.
Table 1
Number of cases |
Effective |
Invalid |
Obvious effective rate (%) |
500 |
491 |
9 |
98.2 |
Known by above-mentioned data, Chinese medicine of the present invention is made after decoction, can be in 10 days the treatment diabetes insipidus of highly significant.
embodiment 3
The decoction administration ICR mice that uses embodiment 1 to make, body weight 20 ~ 25g, male and female half and half, successive administration 60d.
Through prerun, the decoction toxicity that embodiment 1 makes is very low, does not measure LD50, measures therefore mice is carried out to maximum dosage-feeding on the one.Maximum dosage-feeding is 400ml/d, observes none example and be poisoned to death after 60 days, and all healthy survival, proves that the decoction that compositions of the present invention is made can toxic side effect to human body thus.