CN105362491A - External-use medicine for treating cervical vertebra hyperosteogeny - Google Patents
External-use medicine for treating cervical vertebra hyperosteogeny Download PDFInfo
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- CN105362491A CN105362491A CN201510831726.4A CN201510831726A CN105362491A CN 105362491 A CN105362491 A CN 105362491A CN 201510831726 A CN201510831726 A CN 201510831726A CN 105362491 A CN105362491 A CN 105362491A
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Abstract
The invention relates to external-use medicine for treating cervical vertebra hyperosteogeny. The external-use medicine is prepared from, by weight, big Mallotus apelta, Toddalia asiatica, Hyptis suaveolens piot, mulberry seed, white Rhizoma polygoni-cuspidatl, red Rhizoma polygoni-cuspidatl, white diamond, big Pilea basicordata, Sarcandra glabra, big Sangufeng and faamh gov buerng. The traditional Chinese medicine composition has exact treatment effect, high safety and no side effect in the aspect of treating cervical vertebra hyperosteogeny caused by impatency of meridians and collaterals due to wind, cold and damp, is convenient to use and low in cost and has better effect than the prior art.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of external used medicine for the treatment of hyperosteogeny of cervical vertebra.
Background technology
Hyperosteogeny causes joint, local, muscle, ligament moving obstacle with sclerotin pathological proliferation, and the pain that occurs together is the disease of cardinal symptom.The places such as cervical vertebra, cervical vertebra, joint and calcaneus can be occurred in, comprise hypertrophy spondylitis, hpertrophic osteoarthropathy and calcanean spur etc.Primary disease is apt to occur in the person in middle and old age of more than 40 years old and is engaged in the staff of load-bearing, for a long time station, sitting, common with the pathological changes of the larger joint of range of activity, vertebra.The cause of disease of bone matrix hyperplasia is not bright so far, belongs to the category of senile degeneration more, a lot of about its etiology and pathogenesis hypothesis, as machinery say, function is said, angiopathy, dysbolism, dyshormonia etc.Basic understandings is on interior gene basis, is caused morbidity by bringing out of exopathogenic factor.Current doctor trained in Western medicine adopts non-hormone antiinflammation pain-stopping pharmaceutical, physical therapy and operative treatment, has certain effect, but there is no special effective therapy so far to relief of symptoms.
Summary of the invention
The object of this invention is to provide a kind of external used medicine for the treatment of hyperosteogeny of cervical vertebra.
The object of the invention is by following technical scheme realize:
The external used medicine for the treatment of hyperosteogeny of cervical vertebra of the present invention is prepared from by the raw material of Chinese medicine of following weight portion:
DABAI leeward 10-30 part, enter mountain tiger 5-20 part, hair tiger 5-20 part, Fructus Mori 10-30 part, Bai Jiuniu 10-30 part, red nine Ns of 10-30 parts, operculina turpethum 5-20 part, whitely bore 10-30 part, anvil 5-20 part, DAJIEGU wind 10-30 part, Herba Pileae Scriptae 3-10 part, large loose GUFENG 10-30 part, Radix Parthenocissi Heterophyllae 3-10 part.
Preferably, be prepared from by the raw material of Chinese medicine of following weight portion:
DABAI leeward 15-25 part, enter mountain tiger 8-15 part, hair tiger 8-15 part, Fructus Mori 15-25 part, Bai Jiuniu 15-25 part, red nine Ns of 15-25 parts, operculina turpethum 8-15 part, whitely bore 15-25 part, anvil 8-15 part, DAJIEGU wind 15-25 part, Herba Pileae Scriptae 5-8 part, large loose GUFENG 15-25 part, Radix Parthenocissi Heterophyllae 5-8 part.
Below the crude drug source of Chinese medicine preparation of the present invention:
DABAI is leeward, the Herb of Asclepiadaceae plant Caulis seu folium hoyaecarnosae Hoyacarnosa (L.f.) R.Br..Bitter in the mouth, property is put down.Heat-clearing and toxic substances removing, expelling wind and removing dampness, reducing swelling and alleviating pain.
Enter mountain tiger, the rhizome of rutaceae Radix Zanthoxyli Zanthoxylumnitidum (Roxb.) DC..Bitter in the mouth, pungent, warm in nature.Slightly poisonous.Expelling wind and activating blood circulation, narcotic analgesic, heat-clearing and toxic substances removing, detumescence, hemostasis.
Hair tiger, the root of ericad rhododendron molle (bl.) g.don RhododendronmolleG.Don or Herb.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis, narcotic analgesic, relieving cough and asthma, detumescence, sterilizing and itch-relieving.
Fructus Mori is the fruit ear of moraceae plants Mulberry.Sweet; Acid; Cold in nature.Liver; Kidney channel.Nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Bai Jiuniu, root, stem, leaf, the fruit of that rattan Stauntoniahexaphylla (Thunb.) Decne.f.inter-mediaWu of the plants of Lardizabalaceae the five fingers.Bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, heart tonifying eases pain, diuretic.
Red nine Ns, root, the rattan of apocynaceae plant parabarium huaitingii Chun et Tsiang ParabariumhuaitingiiChunetTsiang.Bitter in the mouth, micro-pungent, property is put down.Slightly poisonous.Dispelling, collateral-activating, bone and muscle strengthening.
Operculina turpethum, stem, the leaf of menispermaceous plants Tinospora sinensis Tinosporasinensis (Lour) Merr.Mildly bitter flavor, cool in nature.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain.
White brill, root, the rattan of Schisandraceae Kadsura KadsurasP..Acrid in the mouth, warm in nature.Expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling, promoting the circulation of QI to relieve pain.
Anvil, the root of Fructus Lycopersici esculenti branch section plant Radix Fissistigmatis Oldhamii Fissistigmaoldhamii (Hemsl.) Merr.Acrid in the mouth, micro-puckery, warm in nature.Expelling wind and activating blood circulation, reducing swelling and alleviating pain, bone and muscle strengthening.
DAJIEGU wind, the Herb of acanthaceous plant black leaf Rhizoma seu Herba Elatostematis stewardii Gendarussaventricosa (Wall.) Nees.Acrid in the mouth, micro-acid, property is put down.Promoting blood circulation to remove blood stasis, expelling wind and removing dampness, reunion of fractured tendons and bones.
Herba Pileae Scriptae, Urticaceae Herba Pileae Scriptae PileasymmeriaWedd.var.salwinensisHand.-Mazz., with all herbal medicine.Micro-hardship; Puckery; Warm in nature.Blood circulation promoting and blood stasis dispelling.Main traumatic injury; Fracture.
Large loose GUFENG, Sabiaceae plant carries on the back the root of Caulis Sinomenii SabiadiscolorDunn, stem or Herb in vain.Lightly seasoned, property is put down.Loose poison detumescence, expelling wind and removing dampness, pain relieving.
Radix Parthenocissi Heterophyllae is root or the stem of vitaceae great Ye parthenocissus.Hardship, temperature.Expelling wind and removing dampness, dredging collateral, hemostasis, removing toxic substances.Dispelling the wind and dampness pathogens arthralgia pain, migraine, rheumatism sore, fracture.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and the method adopts the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.Concrete preparation method is as follows:
Scheme one: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
Scheme two: get whole medical material, uses 40-80% alcohol reflux 2-3 time after mixing, and each ethanol consumption is 4-10 times of medical material total amount, extraction time is 1-4 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
Scheme three: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, and when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, add ethanol, make alcohol content be 40-70%, leave standstill 12-24 hour, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the extractum of 1.10-1.25, obtains active component.
The external used medicine for the treatment of hyperosteogeny of cervical vertebra of the present invention, is prepared from by the following method: get whole medical material, micronizing, and cross 300-400 mesh sieve, mix homogeneously, adds the flour of 1-2 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
The external used medicine for the treatment of hyperosteogeny of cervical vertebra of the present invention, be prepared from by the following method: get one of scheme one to scheme three gained active component, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, put into Mould Machining molding, to obtain final product.
During use, dough is heated to 40-50 DEG C, fomentation affected part.
Formula of the present invention is rationally innovated, side in DABAI leeward, enter mountain tiger, Radix Parthenocissi Heterophyllae expelling wind and activating blood circulation, heat-clearing and toxic substances removing, reducing swelling and alleviating pain; Hair tiger expelling wind and removing dampness, promoting blood circulation and stopping pain; Fructus Mori nourishing YIN and benefiting blood; Bai Jiuniu heat-clearing and toxic substances removing; Red nine Ns, operculina turpethum, in vain brill, anvil dispelling, collateral-activating, pain relieving bone strengthening; DAJIEGU wind promoting blood circulation to remove blood stasis, expelling wind and removing dampness, reunion of fractured tendons and bones; Herba Pileae Scriptae, large loose GUFENG blood circulation promoting and blood stasis dispelling, dehumidifying detumescence.Full side plays expelling wind and removing dampness altogether, blood circulation promoting and blood stasis dispelling, and the merit of reducing swelling and alleviating pain, is used for the treatment of hyperosteogeny of cervical vertebra.
A kind of external used medicine for the treatment of hyperosteogeny of cervical vertebra provided by the invention has the following advantages:
1, compositions provided by the invention is safe and effective, has expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, and the merit of reducing swelling and alleviating pain, is used for the treatment of hyperosteogeny of cervical vertebra.
2, the total effective rate of compositions treatment hyperosteogeny of cervical vertebra provided by the invention is 92.9%, and treatment hyperosteogeny of cervical vertebra is evident in efficacy.
3, Traditional Chinese medicine composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, the percent of the amount of alcohol in the present invention is percentage by volume, and v/v represents the volume ratio of solution.
Embodiment 1
Take the leeward 1kg of DABAI, enter mountain tiger 0.5kg, hair tiger 0.5kg, Fructus Mori 1kg, Bai Jiuniu 1kg, red nine Ns of 1kg, operculina turpethum 0.5kg, bore 1kg, anvil 0.5kg, DAJIEGU wind 1kg, Herba Pileae Scriptae 0.3kg, large loose GUFENG 1kg, Radix Parthenocissi Heterophyllae 0.3kg in vain.Extracting in water 3 times, three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, three extraction times are respectively 3 hours, 2 hours, 1 hour, merge extractive liquid, filter, when filtrate is concentrated into 70 DEG C, relative density is the clear paste of 1.25, adds the flour of 1 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
Embodiment 2
Take the leeward 3kg of DABAI, enter mountain tiger 2kg, hair tiger 2kg, Fructus Mori 3kg, Bai Jiuniu 3kg, red nine Ns of 3kg, operculina turpethum 2kg, bore 3kg, anvil 2kg, DAJIEGU wind 3kg, Herba Pileae Scriptae 1kg, large loose GUFENG 3kg, Radix Parthenocissi Heterophyllae 1kg in vain.With 40% alcohol reflux 3 times, each ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours, 2 hours, 1 hour respectively extraction time, merge extractive liquid, filter, when filtrate concentrates 60 DEG C, relative density is the extractum of 1.25, adds the flour of 2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
Embodiment 3
Take the leeward 1.5kg of DABAI, enter mountain tiger 0.8kg, hair tiger 0.8kg, Fructus Mori 1.5kg, Bai Jiuniu 1.5kg, red nine Ns of 1.5kg, operculina turpethum 0.8kg, bore 1.5kg, anvil 0.8kg, DAJIEGU wind 1.5kg, Herba Pileae Scriptae 0.5kg, large loose GUFENG 1.5kg, Radix Parthenocissi Heterophyllae 0.5kg in vain.Extracting in water 3 times, three amount of water are equivalent to 12 times, 8 times, 6 times of medical material gross weight respectively, 3 hours, 2 hours, 1 hour respectively each extraction time, merge extractive liquid, filter, when filtrate is concentrated into 70 DEG C, relative density is the clear paste of 1.20, adds ethanol, makes alcohol content be 40%, leave standstill 24 hours, filter, it is the extractum of 1.10 that filtrate is concentrated into relative density when filtrate is concentrated into 70 DEG C, to obtain final product.
Embodiment 4
Take the leeward 2.5kg of DABAI, enter mountain tiger 1.5kg, hair tiger 1.5kg, Fructus Mori 2.5kg, Bai Jiuniu 2.5kg, red nine Ns of 2.5kg, operculina turpethum 1.5kg, bore 2.5kg, anvil 1.5kg, DAJIEGU wind 2.5kg, Herba Pileae Scriptae 0.8kg, large loose GUFENG 2.5kg, Radix Parthenocissi Heterophyllae 0.8kg in vain.With alcohol reflux 2 times, each concentration of alcohol is respectively 80%, 60%, and each ethanol consumption is respectively 10 times, 8 times of medical material total amount, extraction time is respectively 4 hours, 3 hours, merge extractive liquid, filters, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.10, to obtain final product.
Embodiment 5
Take the leeward 2kg of DABAI, enter mountain tiger 1kg, hair tiger 1kg, Fructus Mori 2kg, Bai Jiuniu 2kg, red nine Ns of 2kg, operculina turpethum 1kg, bore 2kg, anvil 1kg, DAJIEGU wind 2kg, Herba Pileae Scriptae 0.7kg, large loose GUFENG 2kg, Radix Parthenocissi Heterophyllae 0.7kg in vain.Get whole medical material, micronizing, cross 300 mesh sieves, mix homogeneously, adds the flour of 1 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
Embodiment 6
Take the leeward 2.3kg of DABAI, enter mountain tiger 1.2kg, hair tiger 0.8kg, Fructus Mori 1.8kg, Bai Jiuniu 2.3kg, red nine Ns of 1.8kg, operculina turpethum 0.6kg, bore 1.2kg, anvil 1.5kg, DAJIEGU wind 2kg, Herba Pileae Scriptae 0.6kg, large loose GUFENG 2.3kg, Radix Parthenocissi Heterophyllae 0.4kg in vain.Get whole medical material, micronizing, cross 400 mesh sieves, mix homogeneously, adds the flour of 2 times of medical material weight, and the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
clinical trial is summed up
1 basic document
Observe hyperosteogeny of cervical vertebra patient 42 example, man 18 example, female 24 example, age 28-70 year, the course of disease gets rid of gestation and women breast-feeding their children, those who are allergic to this drug, late deformity, maimed person, disability person.Patient all haves a medical check-up through x-ray and is diagnosed as hyperosteogeny of cervical vertebra.
2 Therapeutic Method
With the dough of the embodiment of the present invention 5, during use, dough is heated to 40-50 DEG C, fomentation affected part, repeated multiple times, within 1 week, be 1 course for the treatment of, after observing treatment, symptom changes situation, administration time 2 weeks-2 months.
3 curative effect judging standards
Recovery from illness: clinical symptom disappearance, freely, x line check bone matrix hyperplasia does not have growth to local movement, follows up a case by regular visits to without recurrence after 1 year.
Effective: clinical symptoms disappears substantially, local movement is without obviously limited.
Effective: clinical symptoms is obviously improved, tired or can symptom be occurred after catching cold, but comparatively before alleviate to some extent, lighter work can be participated in.
Invalid: 2 ~ 3 courses for the treatment of are treated in medication, clinical symptoms is improved not obvious, and joint movement disorder is unchanged, very then increases the weight of.5 the results are shown in Table 1.
Table 1 efficacy result
| Recovery from illness | Effective | Effectively | Invalid | Effective percentage (%) | |
| Curative effect | 6 | 15 | 18 | 3 | 92.9 |
Clinical effectiveness shows: the external used medicine that the present invention treats hyperosteogeny of cervical vertebra is 92.9% to the total effective rate of hyperosteogeny of cervical vertebra patient, and result shows, the present invention has the curative effect of good treatment hyperosteogeny of cervical vertebra.
Model case:
Case 1: what XX, female, 46 years old.Often feel dizzy, numbness of hand, makes a definite diagnosis hyperosteogeny of cervical vertebra 3 through hospital and saves, and gives the embodiment of the present invention 3 and treats, and treats March, dizzy, numbness of hand transference cure, and continue to strengthen and treat January, after 1 year, further consultation cannot be sent out, and follows up a case by regular visits to better so far.
Although above with general explanation, detailed description of the invention and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (8)
1. treat an external used medicine for hyperosteogeny of cervical vertebra, it is characterized in that it is prepared from by the raw material of Chinese medicine of following weight portion: DABAI leeward 10-30 part, enter mountain tiger 5-20 part, hair tiger 5-20 part, Fructus Mori 10-30 part, Bai Jiuniu 10-30 part, red nine Ns of 10-30 parts, operculina turpethum 5-20 part, whitely bore 10-30 part, anvil 5-20 part, DAJIEGU wind 10-30 part, Herba Pileae Scriptae 3-10 part, large loose GUFENG 10-30 part, Radix Parthenocissi Heterophyllae 3-10 part.
2. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 1, is characterized in that it is prepared from by the raw material of Chinese medicine comprising following weight portion: DABAI leeward 15-25 part, enter mountain tiger 8-15 part, hair tiger 8-15 part, Fructus Mori 15-25 part, Bai Jiuniu 15-25 part, red nine Ns of 15-25 parts, operculina turpethum 8-15 part, whitely bore 15-25 part, anvil 8-15 part, DAJIEGU wind 15-25 part, Herba Pileae Scriptae 5-8 part, large loose GUFENG 15-25 part, Radix Parthenocissi Heterophyllae 5-8 part.
3. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 1 or 2, is characterized in that its active component adopts the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume to be prepared from.
4. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
5. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, 40-80% alcohol reflux 2-3 time is used after mixing, each ethanol consumption is 4-10 times of medical material total amount, extraction time is 1-4 hour, merge extractive liquid, filters, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, obtains active component.
6. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 3, it is characterized in that its active component is prepared from by the following method: get whole medical material, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6-12 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the clear paste of 1.15-1.20, add ethanol, alcohol content is made to be 40-70%, leave standstill 12-24 hour, filter, when filtrate is concentrated into 70-80 DEG C, relative density is the extractum of 1.10-1.25, obtain active component.
7. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 1 or 2, it is characterized in that what described external used medicine was prepared from by the following method: get whole medical material, micronizing, cross 300-400 mesh sieve, mix homogeneously, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, to obtain final product.
8. the external used medicine for the treatment of hyperosteogeny of cervical vertebra as claimed in claim 3, it is characterized in that what described external used medicine was prepared from by the following method: get gained active component, add the flour of 1-2 times of medical material weight, the rubbing that adds water is not fallen apart to agglomerating, put into Mould Machining molding, to obtain final product.
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| CN111514261A (en) * | 2020-04-30 | 2020-08-11 | 罗捷 | Yao medicine head treatment powder capable of dispelling wind and dredging orifices and preparation method thereof |
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Application publication date: 20160302 |