CN103251900B - Drug for treating dysmenorrhea - Google Patents

Drug for treating dysmenorrhea Download PDF

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Publication number
CN103251900B
CN103251900B CN201310141204.2A CN201310141204A CN103251900B CN 103251900 B CN103251900 B CN 103251900B CN 201310141204 A CN201310141204 A CN 201310141204A CN 103251900 B CN103251900 B CN 103251900B
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parts
grams
dysmenorrhea
drug
treatment
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CN201310141204.2A
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CN103251900A (en
Inventor
苑存忠
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Qilu Hospital of Shandong University
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Qilu Hospital of Shandong University
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Abstract

The invention discloses a drug for treating dysmenorrhea. The drug is prepared from the following active pharmaceutical ingredients in parts by weight: 15-25 parts of motherwort herb, 10-12 parts of radix bupleuri, 8-10 parts of Chinese angelica, 5-8 parts of white paeony root, 5-8 parts of cinnamon, 12-15 parts of Indian buead, 12-15 parts of liquorice, 15-20 parts of dried ginger, 10-15 parts of salvia miltiorrhiza and 10-15 parts of ass hide glue. A preparation method comprises the steps of taking the active pharmaceutical ingredients, adding water to immerse the active pharmaceutical ingredients, decocting the active pharmaceutical ingredients for 1-2 hours, filtering the decoction, then adding water to the dregs to immerse the dregs, decocting the dregs for 0.5-1.5 hours, filtering the decoction and merging the two filtrates, thus obtaining the drug. When used for treating dysmenorrhea, the drug is taken orally once a day, a dose once for seven days. One course of treatment lasts seven days. Generally, the drug takes an effect after being taken for two-three courses of treatment and cures dysmenorrhea after being taken for three-four courses of treatment. Through many years of clinical verifications, the drug for treating dysmenorrhea has good curative effects, takes an effect quickly, does not have toxic or side effects, is simple to prepare and convenient to take, is simple in obtaining materials, is low in price and is mainly used for treating primary dysmenorrhea.

Description

A kind of medicine for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of medicine for the treatment of dysmenorrhea.
Background technology
Primary dysmenorrhea and primary dysmenorrhea, dysmenorrhea refers to painful menstrual periods, normal in spastic, concentrate on other symptoms of hypogastric region, comprise headache weak, dizzy, nausea and vomiting, diarrhoea, lumbago and skelalgia, how caused by deficient qi and blood, qi depression to blood stasis, cold and stagnate, it is the very common pertinacious disease of young woman, painful large, sickness rate is high, has a strong impact on work and the life of people.The technology of existing treatment dysmenorrhea is a lot, and Chinese medicine is long for the course for the treatment of, and effect is slow, and what have goes back toxic side effect, and Western medicine then adopts the simple temporarily pain relieving of tablet for alleviating pain usually, and effect is bad.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of medicine for the treatment of dysmenorrhea, its good effect, instant effect, has no side effect, and preparation is simple, cheap.
The present invention is achieved by the following technical solutions:
Treating a medicine for dysmenorrhea, is be made up of the crude drug of following weight portion: Herba Leonuri 15 ~ 25 parts, Radix Bupleuri 10 ~ 12 parts, Radix Angelicae Sinensis 8 ~ 10 parts, the Radix Paeoniae Alba 5 ~ 8 parts, Cortex Cinnamomi 5 ~ 8 parts, 12 ~ 15 parts, Poria, 12 ~ 15 parts, Radix Glycyrrhizae, Rhizoma Zingiberis 15 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 15 parts, 10 ~ 15 parts, Colla Corii Asini.
Preferably, be made up of following crude drug: Herba Leonuri 20 grams, Radix Bupleuri 11 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 7 grams, Cortex Cinnamomi 7 grams, 13 grams, Poria, 14 grams, Radix Glycyrrhizae, Rhizoma Zingiberis 18 grams, Radix Salviae Miltiorrhizae 12 grams, 12 grams, Colla Corii Asini (this amount is the amount of potion).
The preparation method of the Chinese medicine preparation of described treatment dysmenorrhea is: get each crude drug, add water to submerge, and decocts 1 ~ 2 hour, and filter, then add water in medicinal residues, submergence, decocts 0.5 ~ 1.5 hour, filters, merges the filtrate of twice, to obtain final product.
The Chinese medicine preparation for the treatment of dysmenorrhea of the present invention, cures mainly primary dysmenorrhea; During treatment, oral, once a day, each potion, serve on 7, within 7th, is a course for the treatment of.General 2 ~ 3 courses for the treatment of take effect, and 3 ~ 4 courses for the treatment of cure.
The medicine for the treatment of dysmenorrhea of the present invention, the pharmacological property of its each crude drug is as follows:
Herba Leonuri: acrid in the mouth is bitter, cool, have invigorate blood circulation, blood stasis dispelling, regulating menstruation, the water that disappears effect.
Radix Bupleuri: cold nature, bitter in the mouth, pungent, tool depressed liver-energy dispersing and function of gallbladder promoting, dredges gas resolving depression, loose effect of fire.
Radix Angelicae Sinensis: sweet in the mouth, warm in nature, can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.
The Radix Paeoniae Alba: picric acid, cool, can nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.
Cortex Cinnamomi: extremely hot in nature, acrid in the mouth, sweet, can diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian.
Poria: odorless, lightly seasoned, mild in medicine property and, dampness removing and do not hinder healthy energy.
Radix Glycyrrhizae: sweet in the mouth, property is put down, nontoxic, can heat-clearing and toxic substances removing, has slow healthy energy, yin nourishing blood, except effect of pathogenic heat.
Rhizoma Zingiberis: acrid in the mouth, hot in nature, have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention effect.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold, nontoxic, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, and clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind.
Colla Corii Asini: feeble QI, the micro-Gan Kou of taste, YIN nourishing of enriching blood, moisturizes, hemostasis.
The present invention choose Herba Leonuri, Radix Bupleuri, when being classified as monarch drug, promoting blood flow to regulate menstruation; The Radix Paeoniae Alba, Cortex Cinnamomi, Poria, Radix Glycyrrhizae are nourished blood, healthy energy, are ministerial drug altogether, help with Rhizoma Zingiberis, Radix Salviae Miltiorrhizae, Colla Corii Asini; All medicines share, and compatibility is reasonable, clear curative effect, promoting flow of QI and blood, the stagnant blood stasis dispelling of row, and warming the interior cold expelling meets primary disease treatment.
The medicine for the treatment of dysmenorrhea of the present invention, through clinical verification for many years, good effect, instant effect, has no side effect, and preparation is simple, taking convenience, draws materials simple, cheap, is mainly used in treating primary dysmenorrhea.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the medicine for the treatment of dysmenorrhea
Formula is: Herba Leonuri 20 grams, Radix Bupleuri 11 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 7 grams, Cortex Cinnamomi 7 grams, 13 grams, Poria, 14 grams, Radix Glycyrrhizae, Rhizoma Zingiberis 18 grams, Radix Salviae Miltiorrhizae 12 grams, 12 grams, Colla Corii Asini.
Preparation method is: get each crude drug, add water to submerge, and decocts 1.5 hours, and filter, then add water in medicinal residues, submergence, decocts 1 hour, filters, merges the filtrate of twice, to obtain final product.
During treatment, oral, once a day, each potion, serve on 7, within 7th, is a course for the treatment of.
Embodiment 2 prepares the medicine for the treatment of dysmenorrhea
Formula is: Herba Leonuri 15 grams, Radix Bupleuri 10 grams, Radix Angelicae Sinensis 8 grams, the Radix Paeoniae Alba 5 grams, Cortex Cinnamomi 5 grams, 12 grams, Poria, 12 grams, Radix Glycyrrhizae, Rhizoma Zingiberis 15 grams, Radix Salviae Miltiorrhizae 10 grams, 10 grams, Colla Corii Asini.
All the other are identical with embodiment 1.
Embodiment 3 prepares the medicine for the treatment of dysmenorrhea
Formula is: Herba Leonuri 25 grams, Radix Bupleuri 12 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 8 grams, Cortex Cinnamomi 8 grams, 15 grams, Poria, 15 grams, Radix Glycyrrhizae, Rhizoma Zingiberis 20 grams, Radix Salviae Miltiorrhizae 15 grams, 15 grams, Colla Corii Asini.
All the other are identical with embodiment 1.
Clinical verification
(1) physical data
The medicine that Application Example 1 is made carries out clinical treatment to 70 routine patients, and the age of patient is at 14 ~ 39 years old, most of unmarried, is primary dysmenorrhea.
(2) Therapeutic Method
Starting to take from clean period first day, serve on 7,7th is a course for the treatment of.Unhealed, then next menstrual cycle proceeds the next course for the treatment of.Healing person, no longer takes.
(3) the standard of curative effect evaluation:
Cure: clinical symptom disappearance, functional activity is normal, and next menstruation is without hypogastralgia.
Take a turn for the better: clinical symptoms partial disappearance or be clearly better.
Invalid: Clinical symptom and sign is without improvement.
(4) therapeutic effect
Most of patients is taken 3 ~ 4 courses for the treatment of and can be cured, the course of disease is longer, the state of an illness than more severe case, 6 ~ 8 courses for the treatment of need be taken, specific as follows:
After treating three courses for the treatment of: cure 39 examples, take a turn for the better 28 examples, invalid 3 examples.
After treating five courses for the treatment of: cure 62 examples, take a turn for the better 8 examples, invalid 0 example.
Model case
1, king so-and-so, female, 28 years old, menstrual period hypogastralgia unbearably, fear of cold is afraid of cold, palpitation and short breath, cold perspiration, pale complexion.Take medicine of the present invention (embodiment 1) to treat, after treating for 2 courses for the treatment of, symptom alleviates, and takes 4 courses for the treatment of, transference cure, continues to strengthen 2 courses for the treatment of, recurrence that so far there are no.
2, high so-and-so, female, 17 years old, patient, from 12 years old menarche, namely suffered from dysmenorrhea, abdominal pain in menstruation, and feel sick, weak, cold perspiration, cold limbs, has a strong impact on study, and through multiple treatment, effect is bad.After take medicine of the present invention (embodiment 1) and treat, after treating for 3 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, cures.Recurrence of following up a case by regular visits to that so far there are no.

Claims (3)

1. treat the medicine of dysmenorrhea for one kind, it is characterized in that: be made up of the crude drug of following weight portion: Herba Leonuri 15 ~ 25 parts, Radix Bupleuri 10 ~ 12 parts, Radix Angelicae Sinensis 8 ~ 10 parts, the Radix Paeoniae Alba 5 ~ 8 parts, Cortex Cinnamomi 5 ~ 8 parts, 12 ~ 15 parts, Poria, 12 ~ 15 parts, Radix Glycyrrhizae, Rhizoma Zingiberis 15 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 15 parts, 10 ~ 15 parts, Colla Corii Asini.
2. a kind of medicine for the treatment of dysmenorrhea according to claim 1, is characterized in that: be made up of following crude drug: Herba Leonuri 20 grams, Radix Bupleuri 11 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 7 grams, Cortex Cinnamomi 7 grams, 13 grams, Poria, 14 grams, Radix Glycyrrhizae, Rhizoma Zingiberis 18 grams, Radix Salviae Miltiorrhizae 12 grams, 12 grams, Colla Corii Asini.
3. a kind of preparation method for the treatment of the medicine of dysmenorrhea described in claim 1 or 2, is characterized in that: get each crude drug, add water to submerge, and decocts 1 ~ 2 hour, filter, then add water in medicinal residues, submergence, decocts 0.5 ~ 1.5 hour, filter, merge the filtrate of twice, to obtain final product.
CN201310141204.2A 2013-04-22 2013-04-22 Drug for treating dysmenorrhea Expired - Fee Related CN103251900B (en)

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Application Number Priority Date Filing Date Title
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CN103251900B true CN103251900B (en) 2015-02-18

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729640A (en) * 2016-12-23 2017-05-31 郑州莉迪亚医药科技有限公司 A kind of medicine for treating dysmenorrhoea
CN107596321A (en) * 2017-10-17 2018-01-19 广西西林县农本生物科技有限公司 It is a kind of to be used to treat composition containing ginger of dysmenorrhoea and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"温经汤加减治疗阳虚寒凝血瘀型原发性痛经临床观察";温景荣;《中国优秀硕士学位论文全文数据库 医药卫生科技辑》;20040315(第01期);E056-160 *

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