CN103251899B - Oral drug for treating dysmenorrhea - Google Patents

Oral drug for treating dysmenorrhea Download PDF

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Publication number
CN103251899B
CN103251899B CN201310141196.1A CN201310141196A CN103251899B CN 103251899 B CN103251899 B CN 103251899B CN 201310141196 A CN201310141196 A CN 201310141196A CN 103251899 B CN103251899 B CN 103251899B
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China
Prior art keywords
parts
grams
dysmenorrhea
treatment
oral drug
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Expired - Fee Related
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CN201310141196.1A
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Chinese (zh)
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CN103251899A (en
Inventor
苑存忠
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Qilu Hospital of Shandong University
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Qilu Hospital of Shandong University
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Abstract

The invention discloses an oral drug for treating dysmenorrhea. The oral drug is prepared from the following active pharmaceutical ingredients in parts by weight: 12-15 parts of Sichuan lovage rhizome, 12-15 parts of combined spicebush root, 5-8 parts of frankincense, 15-20 parts of rhizoma corydalis, 12-15 parts of dried ginger, 15-20 parts of motherwort herb, 5-10 parts of liquorice, 8-10 parts of dried tangerine peel, 12-15 parts of Chinese yam, 10-12 parts of hawthorn and 10-15 parts of ass hide glue. A preparation method comprises the steps of taking the active pharmaceutical ingredients, adding water to immerse the active pharmaceutical ingredients, decocting the active pharmaceutical ingredients for 1-2 hours, filtering the decoction, then adding water to the dregs to immerse the dregs, decocting the dregs for 0.5-1.5 hours, filtering the decoction and merging the two filtrates, thus obtaining the oral drug. When used for treating dysmenorrhea, the oral drug is taken once a day, a dose once for seven days. One course of treatment lasts seven days. Generally, the oral drug takes an effect after being taken for two-three courses of treatment and cures dysmenorrhea after being taken for three-four courses of treatment. Through many years of clinical verifications, the oral drug for treating dysmenorrhea has good curative effects, takes an effect quickly, does not have toxic or side effects and is mainly used for treating primary dysmenorrhea.

Description

A kind of oral drugs for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of oral drugs for the treatment of dysmenorrhea.
Background technology
Primary dysmenorrhea and primary dysmenorrhea, dysmenorrhea refers to painful menstrual periods, normal in spastic, concentrate on other symptoms of hypogastric region, comprise headache weak, dizzy, nausea and vomiting, diarrhoea, lumbago and skelalgia, how caused by deficient qi and blood, qi depression to blood stasis, cold and stagnate, it is the very common pertinacious disease of young woman, painful large, sickness rate is high, has a strong impact on work and the life of people.The technology of existing treatment dysmenorrhea is a lot, and Chinese medicine is long for the course for the treatment of, and effect is slow, and what have goes back toxic side effect, and Western medicine then adopts the simple temporarily pain relieving of tablet for alleviating pain usually, and effect is bad.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of oral drugs for the treatment of dysmenorrhea, its good effect, instant effect, has no side effect, and preparation is simple, cheap.
The present invention is achieved by the following technical solutions:
A kind of oral drugs for the treatment of dysmenorrhea, be made up of the crude drug of following weight portion: Rhizoma Chuanxiong 12 ~ 15 parts, the Radix Linderae 12 ~ 15 parts, Olibanum 5 ~ 8 parts, Rhizoma Corydalis 15 ~ 20 parts, Rhizoma Zingiberis 12 ~ 15 parts, Herba Leonuri 15 ~ 20 parts, 5 ~ 10 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 8 ~ 10 parts, Rhizoma Dioscoreae 12 ~ 15 parts, Fructus Crataegi 10 ~ 12 parts, 10 ~ 15 parts, Colla Corii Asini.
Preferably, be made up of following crude drug: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, 8 grams, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, 13 grams, Colla Corii Asini (this amount is the amount of potion).
The preparation method of the oral drugs of described treatment dysmenorrhea is: get each crude drug, add water to submerge, and decocts 1 ~ 2 hour, and filter, then add water in medicinal residues, submergence, decocts 0.5 ~ 1.5 hour, filters, merges the filtrate of twice, to obtain final product.
The oral drugs for the treatment of dysmenorrhea of the present invention, cure mainly primary dysmenorrhea; During treatment, oral, once a day, each potion, serve on 7, within 7th, is a course for the treatment of.General 2 ~ 3 courses for the treatment of take effect, and 3 ~ 4 courses for the treatment of cure.
The oral drugs for the treatment of dysmenorrhea of the present invention, the pharmacological property of its each crude drug is as follows:
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel, blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.
The Radix Linderae: acrid in the mouth, warm in nature.Return lung, spleen, kidney, urinary bladder channel, tool be pleasant, dissipating depression of QI, cold expelling, analgesic efficacy.
Olibanum: property acrid, bitter, warm.Have invigorate blood circulation, circulation of qi promoting, analgesic efficacy.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.Can promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving.
Rhizoma Zingiberis: acrid in the mouth, hot in nature, have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention effect.
Herba Leonuri: acrid in the mouth is bitter, cool, have invigorate blood circulation, blood stasis dispelling, regulating menstruation, the water that disappears effect.
Radix Glycyrrhizae: sweet in the mouth, property is put down, nontoxic.Can treating disorders in five ZANG-organs six internal organs cold and heat pathogen, yin nourishing blood, tonifying the spleen and stomach, lung moistening.
Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, bitter in the mouth, tool regulating qi-flowing for strengthening spleen, in tune, dampness, effect of reducing phlegm.
Rhizoma Dioscoreae: sweet in the mouth, property are flat, nontoxic, can spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.
Fructus Crataegi: tepor, sweet, sour, have blood circulation promoting and blood stasis dispelling, stomach invigorating disappears stagnant effect.
Colla Corii Asini: feeble QI, the micro-Gan Kou of taste, YIN nourishing of enriching blood, moisturizes, hemostasis.
The present invention chooses Rhizoma Chuanxiong, the Radix Linderae, Olibanum, unit act like a bully monarch drug, promoting the circulation of QI to relieve pain; Rhizoma Zingiberis, Herba Leonuri, Radix Glycyrrhizae, Pericarpium Citri Reticulatae are nourished blood, warming middle-JIAO, are ministerial drug altogether, help with Rhizoma Dioscoreae, Fructus Crataegi, Colla Corii Asini; All medicines share, and compatibility is reasonable, clear curative effect, promoting the circulation of QI to relieve pain, nourish blood, warming middle-JIAO, YIN nourishing, meet primary disease treatment.
The oral drugs for the treatment of dysmenorrhea of the present invention, through clinical verification for many years, good effect, instant effect, has no side effect, and preparation is simple, taking convenience, draws materials simple, cheap, is mainly used in treating primary dysmenorrhea.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the medicine for the treatment of dysmenorrhea
Formula is: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, 8 grams, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, 13 grams, Colla Corii Asini.
Preparation method is: get each crude drug, add water to submerge, and decocts 1.5 hours, and filter, then add water in medicinal residues, submergence, decocts 1 hour, filters, merges the filtrate of twice, to obtain final product.
During treatment, oral, once a day, each potion, serve on 7, within 7th, is a course for the treatment of.
Embodiment 2 prepares the medicine for the treatment of dysmenorrhea
Formula is: Rhizoma Chuanxiong 12 grams, the Radix Linderae 12 grams, Olibanum 5 grams, Rhizoma Corydalis 15 grams, Rhizoma Zingiberis 12 grams, Herba Leonuri 15 grams, 5 grams, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 8 grams, Rhizoma Dioscoreae 12 grams, Fructus Crataegi 10 grams, 10 grams, Colla Corii Asini.
All the other are identical with embodiment 1.
Embodiment 3 prepares the medicine for the treatment of dysmenorrhea
Formula is: Rhizoma Chuanxiong 15 grams, the Radix Linderae 15 grams, Olibanum 8 grams, Rhizoma Corydalis 20 grams, Rhizoma Zingiberis 15 grams, Herba Leonuri 20 grams, 10 grams, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 10 grams, Rhizoma Dioscoreae 15 grams, Fructus Crataegi 12 grams, 15 grams, Colla Corii Asini.
All the other are identical with embodiment 1.
Clinical verification
(1) physical data
The medicine that Application Example 1 is made carries out clinical treatment to 80 routine patients, and the age of patient is at 14 ~ 44 years old, most of unmarried, is primary dysmenorrhea.
(2) Therapeutic Method
Starting to take from clean period first day, serve on 7,7th is a course for the treatment of.Unhealed, then next menstrual cycle proceeds the next course for the treatment of.Healing person, no longer takes.
(3) the standard of curative effect evaluation:
Cure: clinical symptom disappearance, functional activity is normal, and next menstruation is without hypogastralgia.
Take a turn for the better: clinical symptoms partial disappearance or be clearly better.
Invalid: Clinical symptom and sign is without improvement.
(4) therapeutic effect
Most of patients is taken 3 ~ 4 courses for the treatment of and can be cured, the course of disease is longer, the state of an illness than more severe case, 6 ~ 8 courses for the treatment of need be taken, specific as follows:
After treating three courses for the treatment of: cure 45 examples, take a turn for the better 32 examples, invalid 3 examples.
After treating five courses for the treatment of: cure 66 examples, take a turn for the better 14 examples, invalid 0 example.
Model case
1, Yang, female, 27 years old, menstrual phase abdomen hurt like hell, pernicious vomiting, extremity were ice-cold, nervous, cold perspiration.Take medicine of the present invention (embodiment 1) to treat, after treating for 2 courses for the treatment of, symptom alleviates, and takes 4 courses for the treatment of, transference cure, continues to strengthen 2 courses for the treatment of, recurrence that so far there are no.
2, Lee so-and-so, female, 17 years old, patient from 12 years old menarche, 14 years old initial trouble dysmenorrhea, menstrual period hypogastralgia, feel sick unbearably, pale complexion, limbs fatigue, has a strong impact on study, and for many years through multiple treatment, effect is bad.After take medicine of the present invention (embodiment 1) and treat, after treating for 3 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, cures.Recurrence of following up a case by regular visits to that so far there are no.

Claims (3)

1. treat the oral drugs of dysmenorrhea for one kind, it is characterized in that: be made up of the crude drug of following weight portion: Rhizoma Chuanxiong 12 ~ 15 parts, the Radix Linderae 12 ~ 15 parts, Olibanum 5 ~ 8 parts, Rhizoma Corydalis 15 ~ 20 parts, Rhizoma Zingiberis 12 ~ 15 parts, Herba Leonuri 15 ~ 20 parts, 5 ~ 10 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 8 ~ 10 parts, Rhizoma Dioscoreae 12 ~ 15 parts, Fructus Crataegi 10 ~ 12 parts, 10 ~ 15 parts, Colla Corii Asini.
2. a kind of oral drugs for the treatment of dysmenorrhea according to claim 1, is characterized in that: be made up of following crude drug: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, 8 grams, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, 13 grams, Colla Corii Asini.
3. a kind of preparation method for the treatment of the oral drugs of dysmenorrhea described in claim 1 or 2, is characterized in that: get each crude drug, add water to submerge, and decocts 1 ~ 2 hour, filter, then add water in medicinal residues, submergence, decocts 0.5 ~ 1.5 hour, filter, merge the filtrate of twice, to obtain final product.
CN201310141196.1A 2013-04-22 2013-04-22 Oral drug for treating dysmenorrhea Expired - Fee Related CN103251899B (en)

Priority Applications (1)

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CN103251899B true CN103251899B (en) 2015-01-28

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105361994A (en) * 2015-10-23 2016-03-02 河北工程大学 Portable dysmenorrhea treatment instrument capable of massaging and generating heat
CN106036880B (en) * 2016-07-13 2019-03-22 广州正广生物科技有限公司 A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea
CN108392615A (en) * 2018-05-11 2018-08-14 耿全好 A kind of drug of pure Chinese medicine treatment constipation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"温经汤加减治疗阳虚寒凝血瘀型原发性痛经临床观察";温景荣;《中国优秀硕士学位论文全文数据库 医药卫生科技辑》;20040315(第01期);E056-160 *

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