CN103251899A - Oral drug for treating dysmenorrhea - Google Patents

Oral drug for treating dysmenorrhea Download PDF

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Publication number
CN103251899A
CN103251899A CN2013101411961A CN201310141196A CN103251899A CN 103251899 A CN103251899 A CN 103251899A CN 2013101411961 A CN2013101411961 A CN 2013101411961A CN 201310141196 A CN201310141196 A CN 201310141196A CN 103251899 A CN103251899 A CN 103251899A
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China
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parts
grams
treatment
dysmenorrhea
rhizoma
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CN2013101411961A
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CN103251899B (en
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苑存忠
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Qilu Hospital of Shandong University
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Qilu Hospital of Shandong University
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Abstract

The invention discloses an oral drug for treating dysmenorrhea. The oral drug is prepared from the following active pharmaceutical ingredients in parts by weight: 12-15 parts of Sichuan lovage rhizome, 12-15 parts of combined spicebush root, 5-8 parts of frankincense, 15-20 parts of rhizoma corydalis, 12-15 parts of dried ginger, 15-20 parts of motherwort herb, 5-10 parts of liquorice, 8-10 parts of dried tangerine peel, 12-15 parts of Chinese yam, 10-12 parts of hawthorn and 10-15 parts of ass hide glue. A preparation method comprises the steps of taking the active pharmaceutical ingredients, adding water to immerse the active pharmaceutical ingredients, decocting the active pharmaceutical ingredients for 1-2 hours, filtering the decoction, then adding water to the dregs to immerse the dregs, decocting the dregs for 0.5-1.5 hours, filtering the decoction and merging the two filtrates, thus obtaining the oral drug. When used for treating dysmenorrhea, the oral drug is taken once a day, a dose once for seven days. One course of treatment lasts seven days. Generally, the oral drug takes an effect after being taken for two-three courses of treatment and cures dysmenorrhea after being taken for three-four courses of treatment. Through many years of clinical verifications, the oral drug for treating dysmenorrhea has good curative effects, takes an effect quickly, does not have toxic or side effects and is mainly used for treating primary dysmenorrhea.

Description

A kind of oral drugs for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of oral drugs for the treatment of dysmenorrhea.
Background technology
Primary dysmenorrhea is primary dysmenorrhea, dysmenorrhea refers to menstrual phase pain, often be spastic, concentrate on other symptoms of hypogastric region, comprise weak, dizzy, the nausea and vomiting of headache, diarrhoea, lumbago and skelalgia, how by due to deficient qi and blood, qi depression to blood stasis, the cold and stagnate, it is the very common pertinacious disease of young woman, painful big, the sickness rate height has a strong impact on people's work and life.The technology of existing treatment dysmenorrhea is a lot, and Chinese medicine is long the course for the treatment of, and effect is slow, and what have goes back toxic side effect, and Western medicine then adopts tablet for alleviating pain pain relieving simply temporarily usually, and effect is bad.
Summary of the invention
At above-mentioned prior art, the invention provides a kind of oral drugs for the treatment of dysmenorrhea, its good effect, instant effect has no side effect, and preparation is simple, and is cheap.
The present invention is achieved by the following technical solutions:
A kind of oral drugs for the treatment of dysmenorrhea, made by following bulk drugs: 12~15 parts of Rhizoma Chuanxiongs, 12~15 parts of the Radixs Linderae, 5~8 parts of Olibanums, 15~20 parts of Rhizoma Corydalis, 12~15 parts of Rhizoma Zingiberiss, 15~20 parts of Herba Leonuris, 5~10 parts in Radix Glycyrrhizae, 8~10 parts of Pericarpium Citri Reticulataes, 12~15 parts of Rhizoma Dioscoreaes, 10~12 parts of Fructus Crataegis, 10~15 parts in Colla Corii Asini.
Preferably, made by following crude drug: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, Radix Glycyrrhizae 8 grams, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, Colla Corii Asini 13 grams (this amount is the amount of potion).
The preparation method of the oral drugs of described treatment dysmenorrhea is: get each crude drug, add water to submerge, decocted 1~2 hour, filter, add water again in medicinal residues, submergence decocted 0.5~1.5 hour, filtered, and merged twice filtrate, namely.
The oral drugs for the treatment of dysmenorrhea of the present invention cure mainly primary dysmenorrhea; During treatment, oral, once a day, each potion serve on 7, and 7 is a course for the treatment of.Take effect general 2~3 courses for the treatment of, and cure 3~4 courses for the treatment of.
The oral drugs for the treatment of dysmenorrhea of the present invention, the pharmacological property of its each crude drug is as follows:
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel, blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.
The Radix Linderae: acrid in the mouth, warm in nature.Return lung, spleen, kidney, urinary bladder channel, tool is pleasant, dissipating depression of QI, cold expelling, pain relieving effect.
Olibanum: property suffering, hardship, temperature.Have invigorate blood circulation, circulation of qi promoting, pain relieving effect.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.But promoting blood circulation to remove blood stasis, the promoting the circulation of QI pain relieving.
Rhizoma Zingiberis: acrid in the mouth, hot in nature, have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention effect.
Herba Leonuri: acrid in the mouth hardship, cold, have invigorate blood circulation, the effect of blood stasis dispelling, regulating menstruation, the water that disappears.
Radix Glycyrrhizae: sweet in the mouth, property is flat, and is nontoxic.But treating disorders in five ZANG-organs six internal organs cold and heat pathogen, yin nourishing blood, tonifying the spleen and stomach, lung moistening.
Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, bitter in the mouth, the tool regulating qi-flowing for strengthening spleen, in the accent, dampness, the effect of reducing phlegm.
Rhizoma Dioscoreae: sweet in the mouth, property are flat, nontoxic, can the spleen reinforcing nourishing the stomach, and the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
Fructus Crataegi: tepor, sweet, sour, have blood circulation promoting and blood stasis dispelling, the stomach invigorating stagnant effect that disappears.
Colla Corii Asini: feeble QI, little Gan Kou that distinguishes the flavor of, the YIN nourishing of enriching blood is moisturized, hemostasis.
The present invention chooses Rhizoma Chuanxiong, the Radix Linderae, Olibanum, the unit monarch drug of acting like a bully, promoting the circulation of QI to relieve pain; Rhizoma Zingiberis, Herba Leonuri, Radix Glycyrrhizae, Pericarpium Citri Reticulatae nourish blood, warming middle-JIAO, are ministerial drug altogether, and assistant is with Rhizoma Dioscoreae, Fructus Crataegi, Colla Corii Asini; All medicines share, and compatibility is reasonable, and curative effect is clear and definite, and promoting the circulation of QI to relieve pain nourish blood, warming middle-JIAO, YIN nourishing, meet the primary disease treatment.
The oral drugs for the treatment of dysmenorrhea of the present invention, through clinical verification for many years, good effect, instant effect has no side effect, and preparation is simple, taking convenience, it is simple, cheap to draw materials, and is mainly used in treating primary dysmenorrhea.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment.
The medicine of embodiment 1 preparation treatment dysmenorrhea
Prescription is: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, Radix Glycyrrhizae 8 grams, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, Colla Corii Asini 13 grams.
Preparation method is: get each crude drug, add water to submerge, decocted 1.5 hours, filter, add water again in medicinal residues, submergence decocted 1 hour, filtered, and merged twice filtrate, namely.
During treatment, oral, once a day, each potion serve on 7, and 7 is a course for the treatment of.
The medicine of embodiment 2 preparation treatment dysmenorrheas
Prescription is: Rhizoma Chuanxiong 12 grams, the Radix Linderae 12 grams, Olibanum 5 grams, Rhizoma Corydalis 15 grams, Rhizoma Zingiberis 12 grams, Herba Leonuri 15 grams, Radix Glycyrrhizae 5 grams, Pericarpium Citri Reticulatae 8 grams, Rhizoma Dioscoreae 12 grams, Fructus Crataegi 10 grams, Colla Corii Asini 10 grams.
All the other are identical with embodiment 1.
The medicine of embodiment 3 preparation treatment dysmenorrheas
Prescription is: Rhizoma Chuanxiong 15 grams, the Radix Linderae 15 grams, Olibanum 8 grams, Rhizoma Corydalis 20 grams, Rhizoma Zingiberis 15 grams, Herba Leonuri 20 grams, Radix Glycyrrhizae 10 grams, Pericarpium Citri Reticulatae 10 grams, Rhizoma Dioscoreae 15 grams, Fructus Crataegi 12 grams, Colla Corii Asini 15 grams.
All the other are identical with embodiment 1.
Clinical verification
(1) physical data
The medicine that Application Example 1 is made carries out clinical treatment to 80 routine patients, and patient's age was at 14~44 years old, and is most of unmarried, is primary dysmenorrhea.
(2) Therapeutic Method
Began to take in clean first day from menstruation, serve on 7,7 is a course for the treatment of.Person more, then next menstrual cycle is proceeded the next course for the treatment of.Healing person no longer takes.
(3) therapeutic evaluation standard:
Cure: clinical symptom disappearance, functional activity is normal, and next menstruation does not have hypogastralgia.
Take a turn for the better: clinical symptoms partly disappears or is clearly better.
Invalid: the clinical symptoms sign does not have improvement.
(4) therapeutic effect
Most of patients is taken 3~4 courses for the treatment of and can be cured, and the course of disease is long, state of an illness severe patient relatively, need take 6~8 courses for the treatment of, and is specific as follows:
After treating three courses for the treatment of: cure 45 examples, 32 examples that take a turn for the better, invalid 3 examples.
After treating five courses for the treatment of: cure 66 examples, 14 examples that take a turn for the better, invalid 0 example.
Model case
1, Yang, the woman, 27 years old, menstrual phase abdomen pain unbearably, pernicious vomiting, extremity are ice-cold, nervous, cold perspiration.Take medicine of the present invention (embodiment 1) and treat, treated for 2 courses for the treatment of after, sx is taken 4 courses for the treatment of, transference cure is continued to strengthen 2 courses for the treatment of, does not see recurrence so far.
2, Lee so-and-so, the woman, 17 years old, the patient from 12 years through menophania, 14 years old initial trouble dysmenorrhea, menstrual period, hypogastralgia was felt sick unbearably, pale complexion, limbs fatigue has a strong impact on study, through multiple treatment, effect is bad for many years.After take medicine of the present invention (embodiment 1) and treat, treated for 3 courses for the treatment of after, symptom obviously alleviates, and continues to take 2 courses for the treatment of, cures.Follow up a case by regular visits to and do not see recurrence so far.

Claims (3)

1. oral drugs for the treatment of dysmenorrhea, it is characterized in that: made by following bulk drugs: 12~15 parts of Rhizoma Chuanxiongs, 12~15 parts of the Radixs Linderae, 5~8 parts of Olibanums, 15~20 parts of Rhizoma Corydalis, 12~15 parts of Rhizoma Zingiberiss, 15~20 parts of Herba Leonuris, 5~10 parts in Radix Glycyrrhizae, 8~10 parts of Pericarpium Citri Reticulataes, 12~15 parts of Rhizoma Dioscoreaes, 10~12 parts of Fructus Crataegis, 10~15 parts in Colla Corii Asini.
2. a kind of oral drugs for the treatment of dysmenorrhea according to claim 1 is characterized in that: made by following crude drug: Rhizoma Chuanxiong 14 grams, the Radix Linderae 14 grams, Olibanum 7 grams, Rhizoma Corydalis 18 grams, Rhizoma Zingiberis 13 grams, Herba Leonuri 18 grams, Radix Glycyrrhizae 8 grams, Pericarpium Citri Reticulatae 9 grams, Rhizoma Dioscoreae 13 grams, Fructus Crataegi 11 grams, Colla Corii Asini 13 grams.
3. claim 1 and 2 described a kind of preparation methoies for the treatment of the oral drugs of dysmenorrhea is characterized in that: get each crude drug, add water to submerge, decocted 1~2 hour, filter, add water again in medicinal residues, submergence decocted 0.5~1.5 hour, filter, merge twice filtrate, namely.
CN201310141196.1A 2013-04-22 2013-04-22 Oral drug for treating dysmenorrhea Expired - Fee Related CN103251899B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105361994A (en) * 2015-10-23 2016-03-02 河北工程大学 Portable dysmenorrhea treatment instrument capable of massaging and generating heat
CN106036880A (en) * 2016-07-13 2016-10-26 广州正广生物科技有限公司 Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition
CN108392615A (en) * 2018-05-11 2018-08-14 耿全好 A kind of drug of pure Chinese medicine treatment constipation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
温景荣: ""温经汤加减治疗阳虚寒凝血瘀型原发性痛经临床观察"", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105361994A (en) * 2015-10-23 2016-03-02 河北工程大学 Portable dysmenorrhea treatment instrument capable of massaging and generating heat
CN106036880A (en) * 2016-07-13 2016-10-26 广州正广生物科技有限公司 Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition
CN106036880B (en) * 2016-07-13 2019-03-22 广州正广生物科技有限公司 A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea
CN108392615A (en) * 2018-05-11 2018-08-14 耿全好 A kind of drug of pure Chinese medicine treatment constipation

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