CN106036880A - Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition - Google Patents

Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition Download PDF

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CN106036880A
CN106036880A CN201610547438.0A CN201610547438A CN106036880A CN 106036880 A CN106036880 A CN 106036880A CN 201610547438 A CN201610547438 A CN 201610547438A CN 106036880 A CN106036880 A CN 106036880A
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powder
parts
dysmenorrhea
composition
compositions
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CN106036880B (en
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蒋丽
马丽霞
蒋镇
高艺萍
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Guangzhou Zhengguang Biotechnology Co Ltd
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Guangzhou Zhengguang Biotechnology Co Ltd
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/7016Disaccharides, e.g. lactose, lactulose
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    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a composition for relieving dysmenorrhea, application thereof and healthy food prepared from the composition. The composition for relieving dysmenorrhea is prepared from, by weight, 50-80 parts of brown powdered sugar, 2-8 parts of instant donkey hide gelatin powder, 1-4 parts of fresh ginger extract, 0.08-3 parts of EDTA ferric sodium salt, 1-5 parts of ginseng powder, 1-10 parts of milk mineral salt, 1-5 parts of hawthorn powder, 1-5 parts of yam flour, 2-10 parts of red date powder, 0.1-3 parts of cinnamon powder, 0.05-3 parts of saussurea involucrate culture and 0.0001-0.0005 part of folic acid. According to the formula of the composition, food raw materials are adopted as materials, original ecology is kept, no preservative or fresh keeping agent or other additives are added, the composition is safe to eat, and has no obvious adverse reactions or toxic and side effects after being taken for a long time, and it is proved through the crowd test that the composition has a remarkable effect of relieving dysmenorrhea after being taken.

Description

A kind of compositions alleviating dysmenorrhea and application thereof and the health food being made from
Technical field
The present invention relates to field of food, be specifically related to a kind of compositions alleviating dysmenorrhea and application thereof and be made from strong Health food.
Background technology
Primary dysmenorrhea refer to mature women be expert at through front and back or menstrual period occur stomachache, the soreness of waist, lower abdomen falling inflation or its He is uncomfortable.Modern popular disease research shows, the prevalence of dysmenorrhea is 33-90%, has a strong impact on the live and work of women.
The method of existing treatment dysmenorrhea mostly is Drug therapy, mainly includes that (1) takes PGSI, as Conventional medicine has ibuprofen, ketoprofen, meclofenamic acid, diclofenac etc.;(2) take oral contraceptive and (be applicable to requirement The dysmenorrhea women of contraception).Both the above types of drug all has a more contraindication, and with gastrointestinal upset etc. many bad instead Should.
Along with the quickening day by day of modern society's rhythm of life, easy to carry and use and long-term taking has no side effect safely Product increasingly favored.Health food is the one of food, has the general character of normal food, and its raw material is mainly taken from Natural animals and plants, through modernization vanguard technology, are fabricated to the dosage form food such as tablet, granule, powder, capsule, phase For traditional food, it is aesthetic in appearance, carry with instant, be eaten for a long time safety and have no side effect, the modern day for human beings can be met Normal allegro life and health demand.
Therefore, for the dysmenorrhea of women, develop a kind of health food alleviating dysmenorrhea and have important practical significance.
Summary of the invention
In consideration of it, the primary and foremost purpose of the present invention is to provide a kind of compositions alleviating dysmenorrhea, said composition has substantially Alleviate the effect of dysmenorrhea, and edible safety, have no side effect.
Another object of the present invention is to the compositions that above-mentioned alleviation dysmenorrhea is provided in dysmenorrhea health food is alleviated in preparation Application.
It is still another object of the present invention to provide the health food of the compositions comprising above-mentioned alleviation dysmenorrhea.
The present invention is to be achieved through the following technical solutions:
A kind of compositions alleviating dysmenorrhea, is made up of the raw material of following portions by weight:
Brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens extract 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part,
Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, Rhizoma Dioscoreae powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder 0.1-3 part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
Preferably, the compositions of alleviation dysmenorrhea of the present invention, it is made up of the raw material of following portions by weight:
Brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6 part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng
Powder 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4 part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, snow Lotus culture 0.5-1.5 part, folic acid 0.0002-0.0004 part.
Brown powdered sugar has QI invigorating, helps spleen relieving dyspepsia, effects such as blood stasis dispelling of enriching blood, and also has dispersing cold for relieving pain effect concurrently.So, Nv Xingyin Catch cold, diseases such as unfavorable, dysmenorrhea, the dark red double abdomen cold type of pain of menstruation of passing through caused by blood stasis, drinking a little brown sugar water, often to play treatment gentle Solution effect.Glucose contained by brown sugar releases energy soon, and absorption rate is high, can quickly regain one's strength of body.Brown sugar contains Abundant calcium and ferrum, and calcium and ferrum are mineral and the trace element of needed by human.The traditional Chinese medical science think brown sugar by " temperature and mend it, Wen Ertong it, temperature and dissipate it " and play blood tonification effect.
Instant ass-hide gelatin powder be by Colla Corii Asini through dispensing, dry, pulverize, stir, mix, the processes such as metering, distributing, packaging, packaging Make, there is enriching blood, stop blooding, clearing away lung-heat and moistening for dryness, control cough, control diarrhoea, beauty treatment effect such as hair care.Colla Corii Asini is by collagen protein group Becoming, its hydrolysis can obtain protein, polypeptide and several amino acids.Containing substantial amounts of aminoacid and trace element in Colla Corii Asini, these are all It is leukocyte and the synthesis material of hemoglobin and regulation factor.So, take Colla Corii Asini and contribute to preventing anemia, can help lean Blood, the person of losing blood get well.
Rhizoma Zingiberis Recens extract extracts from Rhizoma Zingiberis Recens, and it mainly comprises volatile oil and gingerol, has relieving exterior syndrome and dispelling cold, warming middle-JIAO Preventing or arresting vomiting, the effect such as preventing phlegm from forming and stopping coughing, for anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough etc..Its distinctive " gingerol " can stimulate stomach Intestinal mucosa, makes gastrointestinal redness, and digestion power strengthens, can effectively treat eat cold and cool food and too much cause abdominal distention, stomachache, Diarrhoea, vomiting etc..
Sodium iron ethylenediaminetetraacetate is a kind of iron enriched nutrient, and iron-holder is about 12-14%, sodium iron ethylenediaminetetraacetate For stable chelate, non-stimulated to gastrointestinal, there is special duodenal absorption, be tightly combined under one's belt, enter duodenum After, ferrum is just released and absorbs, and its absorbance is high, is avoided that the obstacle that chalybeate is absorbed by phytic acid etc., EDTA in absorption process Also can be combined excretion rapidly with harmful element and play the effect of antidote.Sodium iron ethylenediaminetetraacetate have promotion meals in its The effect that his source of iron or endogenous source of iron absorb, may additionally facilitate the absorption of zinc simultaneously, and on the absorption of calcium without impact.
Radix Ginseng powder is the powder made for raw material with Radix Ginseng, and Radix Ginseng belongs to integration of edible and medicinal herbs food, and pharmacopeia records it can complement greatly Gas, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid and nourishes blood, Fructus Alpiniae Oxyphyllae of calming the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed heavily Coughing, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, and prolonged illness void is won, palpitation with fear insomnia, sexual impotence cold womb.
Breast mineral salt belongs to new resource food, has another name called milk calcium, whey mineral concentrate, whey calcium, derives from Lac Bovis seu Bubali, be By Lac Bovis seu Bubali by membrane permeation, the off-white powder that separates, concentrate and obtain after the PROCESS FOR TREATMENT such as spray drying, its main component is Calcium phosphate, the most also includes the nutritional labeling that protein, lactose and zinc, phosphorus, sodium, potassium, magnesium etc. are abundant, and calcium content is about 23%~28%, its calcium-phosphorus ratio is 2: 1, more beneficially the absorbing of human body.Breast mineral salt not only can supplement the absorption of calcium, also The health-care effect such as reduce blood pressure, prevent arteries narrow.
The powder that Fructus Crataegi powder is made up of Fructus Crataegi, have removing food stagnancyization stagnant, convergence the effect such as dysentery relieving, activating blood circulation to dissipate blood stasis, cure mainly diet The diseases such as stagnant, chest and diaphragm feeling of fullness, hernia blood stasis amenorrhea, containing the ingredient such as mountain terpenoid and pyrite class in Fructus Crataegi, have significantly Expansion blood vessel and hypotensive effect, have enhancing cardiac muscle, arrhythmia, regulation blood fat and the function of cholesterol level, be used for treating Coronary heart disease, hypertension, hyperlipidemia etc., it addition, Fructus Crataegi also has function of promoting blood circulation to disperse blood clots, be that the dietetic therapy of blood stasis type dysmenorrhea patient is good Product.
The powdery that Rhizoma Dioscoreae powder is made with Rhizoma Dioscoreae, has spleen invigorating QI invigorating, and lung benefiting reinforces the kidney, the effect such as blood fat reducing, the intestines and stomach coordinating, Rhizoma Dioscoreae contains soluble fiber, can postpone the emptying of gastric food, controls blood glucose after meal and raises.Can also aid digestion, blood sugar lowering.Control Feed processed is intended to as high-nutrition food, containing compositions such as protein, saccharide, vitamin, fat, choline, amylase in Rhizoma Dioscoreae, also Containing the indispensable inorganic salt of human body and trace element such as iodine, calcium, ferrum, phosphorus.
Red date powder contains various bioactivators, as jujube polysaccharide, flavonoid, saponins, triterpenes, alkaloids, Adenosine cyclophosphate, cyclic GMP concentration (cGMP) etc., have plurality kinds of health care to cure the disease effect to human body.It is mainly used in deficiency of QI in middle-JIAO, taste void The treatment of the card such as weak, fatigue and asthenia, anorexia and loose stool, blood deficiency and yellow complexion, women's hysteria.
Cortex Cinnamomi powder is the powder made for raw material with Cortex Cinnamomi, and Cortex Cinnamomi belongs to integration of edible and medicinal herbs food, and pharmacopeia is recorded it and can be mended fire and help Sun, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.For sexual impotence cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, upward floating of YANG in deficiency condition, dizziness mesh Red, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, colic of cold type stomachache, dysmenorrhea amenorrhea.
Saussurea involucrata culture is to choose Herba Saussureae Involueratae callus as subculture seed, is obtained by cell culture technology successive transfer culture , Saussurea involucrata culture contains the multiple active ingredients such as flavone, polysaccharide, chlorogenic acid, syringoside, trace element and terpenoid, has Dispelling cold and removing dampness, effect such as dysmenorrhea, anti-inflammatory and antalgic of invigorating blood circulation, be used for treating rheumatic arthritis, women's cold and pain in the lower abdomen, amenorrhea, paralysis The disease such as impermeable.
Folic acid is a kind of water soluble vitamins, for the necessary material of body cell growth and breeding, helps protein Metabolism, and collectively promote erythrocytic generation and maturation with vitamin B12, it is to manufacture the indispensable material of erythrocyte.
The present invention uses Rhizoma Zingiberis Recens extract relieving exterior syndrome and dispelling cold, Radix Ginseng powder's strongly invigorating primordial QI, the yang-energy of reinforcing the heart, and Cortex Cinnamomi powder complement is positive, Except cold long-pending, warm passages through which vital energy circulates internal organs, release the various pain caused because of cold-evil, red date powder, Rhizoma Dioscoreae powder, instant ass-hide gelatin powder spleen invigorating benefit Stomach, vigorate qi and replenish the blood, brown powdered sugar can supplement rapidly energy to body, and QI and blood abundance can be beneficial to cold and discharges and release pain, Fructus Crataegi Powder, Saussurea involucrata culture can go silt to invigorate blood circulation, anti-inflammatory and antalgic, then are aided with sodium iron ethylenediaminetetraacetate, breast mineral salt and folic acid, supplement people Ferrum needed for body, calcium etc., full side Synergistic, promoting flow of QI and blood, dispersing cold for relieving pain, up to warming up, invigorating spleen and reinforcing stomach, the alleviation dysmenorrhea of dispeling cold Effect.
The compositions that present invention also offers above-mentioned alleviation dysmenorrhea is preparing the application alleviated in dysmenorrhea health food, and this delays Solve the compositions of dysmenorrhea, be made up of the raw material of following portions by weight: brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens carry Take thing 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part, Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, mountain Medicated powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder 0.1-3 part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
Preferably, the proportioning raw materials of the compositions of this alleviation dysmenorrhea is as follows: brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6 Part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng powder's 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4 Part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, Saussurea involucrata culture 0.5-1.5 part, folic acid 0.0002-0.0004 Part.
Dysmenorrhea of the present invention is primary dysmenorrhea.
Present invention also offers a kind of health food, comprise in compositions and the bromatology of the alleviation dysmenorrhea that the present invention provides Acceptable adjuvant.
In bromatology of the present invention acceptable adjuvant can be selected from filler, lubricant, Fruit powder, edible essence, The mixing of one or more in sweeting agent, acidic flavoring agent, preservative, food coloring, disintegrating agent.
Described filler can be starch, Icing Sugar, dextrin, microcrystalline Cellulose, mannitol, lactose, pregelatinized Starch or different One or more in maltulose alcohol;
Described disintegrating agent can be dried starch, carboxymethylstach sodium, low-substituted hydroxypropyl cellulose, polyvinylpolypyrrolidone, crosslinking carboxylic first One or more in base Starch Sodium or cross-linking sodium carboxymethyl cellulose;
Described lubricant can be one or more in magnesium stearate, micropowder silica gel, Polyethylene Glycol or Pulvis Talci;
Described Fruit powder can be one or more in orange powder, orange powder, Fructus Citri Limoniae powder, cherry powder, apple powder or coconut palm powder;
Described edible essence can be that flavoring orange essence, orange essence, Fructus Citri Limoniae essence, cherry essence, Mentholum, apple essence or coconut palm are fragrant One or more in essence;
Described sweeting agent is one or more in sucralose, AK sugar, aspartame or mogroside;
Described acidic flavoring agent is one or more in malic acid, lactic acid or citric acid;
Described preservative is sodium benzoate, Potassium Benzoate, sorbic acid methyl ester, ethylparaben or P-hydroxybenzoic acid benzene
One or more in ester;
Described food coloring is one or more in burnt sugar coloring, Gardenia Yellow, curcumin or chlorophyll.
The dosage form of health food of the present invention can be solid beverage, tablet, granule or capsule, its preparation method Conventional method is used to prepare.Only need brewed in hot water due to solid beverage, Instant Drinks convenience, independent packaging, be easy to carry, because of The dosage form of this health food of the present invention is preferably solid beverage.
The present invention compared with prior art, has the advantages that
(1) formula of the present composition is all with raw-food material as material, keep ecosystem, without any preservative,
The additives such as antistaling agent, edible safety, long-term taking, without obvious untoward reaction and toxic and side effects, tests table through crowd Bright, take this product and there is the effect significantly alleviating dysmenorrhea;
(2) menstrual phase, because internal endocrine change and the contraction in uterus, for calcareous increase in demand, when internal calcium
During content deficiency, emotional instability will be caused, the spasm phenomenon such as organ ache also or in pelvic cavity, the therefore present invention In formula, with the addition of breast mineral salt reach releive blood vessel, the deflation situation of muscle and loosen the effect of emotion as calcium source; It addition, women has universality iron deficiency problem mostly, when menstruation, can make because haemachrome synthesis is not enough and oxygen carrying content is inadequate Complexion is turned white, QI and blood has some setbacks, related impact individual emotion, vigor and memory, therefore the present invention adds second in formula Ethylenediamine tetraacetic acid (EDTA) ferrum sodium supplements " irony " of needed by human body as source of iron;Calcium source, source of iron and other raw material Synergistics in formula, Produce the effect significantly alleviating dysmenorrhea.
Detailed description of the invention
Further illustrating the present invention below by detailed description of the invention, following example are the present invention preferably embodiment party Formula, but embodiments of the present invention are not limited by following embodiment.
The raw material that the embodiment of the present invention is used is as follows:
Instant ass-hide gelatin powder: Donga, Shandong Dongsheng Colla Corii Asini product technology development corporation, Ltd.;Rhizoma Zingiberis Recens extract: commercially available;Ethylenediamine tetraacetic Acetic acid ferrum sodium: Zhengzhou Ruipu Bioengineering Co., Ltd.;Radix Ginseng powder: commercially available;Breast mineral salt: Holland U.S. element (Frieslan Campina);Saussurea involucrata culture: Dalian Puruikang Biotechnology Co;Folic acid: DSM N. V.;Fructus Crataegi powder: commercially available; Rhizoma Dioscoreae powder: commercially available;Red date powder: Tianjin is just like fruit food industry company limited;Cortex Cinnamomi powder: commercially available.
Embodiment 1 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 50 parts, instant ass-hide gelatin powder 8 parts, Rhizoma Zingiberis Recens extract 1 part, sodium iron ethylenediaminetetraacetate 0.08
Part, Radix Ginseng powder 5 parts, breast mineral salt 1 part, Fructus Crataegi powder 5 parts, Rhizoma Dioscoreae powder 5 parts, red date powder 10 parts, Cortex Cinnamomi powder 0.1 part, Herba Saussureae Involueratae Culture 0.05 part, 0.0005 part of folic acid mix and get final product.
Embodiment 2 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3 parts, sodium iron ethylenediaminetetraacetate 2 parts, Radix Ginseng powder 3
Part, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts, Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1 part, folic acid 0.0003 part mixes and get final product.
Embodiment 3 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 80 parts, instant ass-hide gelatin powder 2 parts, Rhizoma Zingiberis Recens extract 4 parts, sodium iron ethylenediaminetetraacetate 3 parts, Radix Ginseng powder 1
Part, breast mineral salt 10 parts, Fructus Crataegi powder 1 part, Rhizoma Dioscoreae powder 1 part, red date powder 2 parts, Cortex Cinnamomi powder 3 parts, Saussurea involucrata culture 3 parts, leaf Acid 0.0001 part mixes and get final product.
The preparation of embodiment 4 health food solid beverage
The compositions of alleviation dysmenorrhea: brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3 parts, sodium iron ethylenediaminetetraacetate 2 parts, Radix Ginseng powder 3 parts, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts, Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1 Part, 0.0003 part of folic acid.
Preparation technology: by above-mentioned raw materials granulation, granulate, mix, enter bag, mounted box, shrink film make finished product.
The preparation of embodiment 5 health food tablet
The compositions of alleviation dysmenorrhea: the compositions of alleviation dysmenorrhea: brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3 Part, sodium iron ethylenediaminetetraacetate 2 parts, Radix Ginseng powder 3 parts, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts, Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1 part, 0.0003 part of folic acid.
Adjuvant: microcrystalline Cellulose 10 parts, Sorbitol 5 parts.
Preparation technology: the compositions of dysmenorrhea, microcrystalline Cellulose, Sorbitol mix homogeneously, tabletting will be alleviated, be distributed into bottle ?.
The beneficial effect of of the present invention prescription is expanded on further by human experiment data.
One, clinical case: 50 example dysmenorrhea patients.All meet following diagnostic criteria:
1. genitals is without significant organic pathological changes person.
2. cardinal symptom: with cold-type pain in the lower abdomen during menstruation falling inflation before and after passing through.
3. simultaneous phenomenon: dark through the few color of blood volume, distending pain of the breast, it to be afraid of cold, profuse leukorrhea, color is white.
4. general malaise: waist is ached, rectal tenesmus, dizzy weak, occur time serious that complexion is turned white perspiration, even suffer a shock Etc. general malaise symptom.
Age 18-48 year.
All cases is primary dysmenorrhea, gets rid of the cause of disease of secondary dysmenorrhea, endometriosis, urgent chronic pelvic inflammatory disease Or cervical stenosis obstruction etc..
All cases is divided into two groups, is 1 menstrual cycle Experiment on therapy group, 1 menstrual cycle treatment matched group respectively.Often Organize 25 examples, two groups of case no significant differences in terms of age, the course of disease and the state of an illness.
Two, Therapeutic Method:
1, experimental group: the solid beverage of embodiment 4, oral, take 1 bag (8g) 30 ~ 60 minutes ante cibum at ordinary times, during pain in menstrual period, drink 1 ~ 2 bags, 1 month are a course for the treatment of.
Matched group: happy redTMColla Corii Asini beverage (celestial happy health), oral, take 1 bottle (8g) 30 ~ 60 minutes ante cibum at ordinary times, menstrual period ache Drink 1 ~ 2 bottle time bitterly, within 1 month, be a course for the treatment of.
2, points for attention: hyperglycemia, hyperpietic are cautious use of.
Three, efficacy assessment standard:
Cure: after treatment, symptom all disappears, and intermenstrual period is without significant discomfort;
Take a turn for the better: after treatment, symptom is obviously improved, occasionally have dysmenorrhea, more slightly;
Invalid: before and after treatment, symptom is not improved.
Four, therapeutic effect:
Taking experimental group 25 example of 1 menstrual cycle, healing is 22 examples, transfers well 2 examples to;Invalid 1 example, total effective rate is 96%; Taking matched group 25 example of 1 menstrual cycle, healing is 15 examples, transfers well 3 examples to;Invalid 7 examples, total effective rate is 72%;Two groups total Effective percentage compares, and experimental group is substantially better than matched group.
Safety observations: do not find any untoward reaction, have no side effect.

Claims (9)

1. the compositions alleviating dysmenorrhea, it is characterised in that be made up of the raw material of following portions by weight:
Brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens extract 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part, Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, Rhizoma Dioscoreae powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder 0.1-3 Part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
The compositions of alleviation dysmenorrhea the most according to claim 1, it is characterised in that by the raw material system of following portions by weight Become:
Brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6 part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng Powder 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4 part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, Herba Saussureae Involueratae training Support thing 0.5-1.5 part, folic acid 0.0002-0.0004 part.
The compositions of alleviation dysmenorrhea the most according to claim 1 and 2, it is characterised in that described sodium iron ethylenediaminetetraacetate The weight content of middle ferrum is 12-14%.
The compositions of alleviation dysmenorrhea the most according to claim 1 and 2, it is characterised in that the weight of calcium in described breast mineral salt Amount content is 23-28%.
5. the compositions of the alleviation dysmenorrhea described in any one of claim 1-4 application in dysmenorrhea health food is alleviated in preparation.
Application the most according to claim 5, it is characterised in that described dysmenorrhea is primary dysmenorrhea.
7. a health food, the compositions comprising the alleviation dysmenorrhea described in any one of claim 1-4 and bromatology can connect The adjuvant being subject to.
Health food the most according to claim 7, it is characterised in that the dosage form of described health food is solid beverage, sheet Agent, granule or capsule.
Health food the most according to claim 8, it is characterised in that the dosage form of described health food is solid beverage.
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