CN106036880A - Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition - Google Patents
Composition for relieving dysmenorrhea, application thereof and healthy food prepared from composition Download PDFInfo
- Publication number
- CN106036880A CN106036880A CN201610547438.0A CN201610547438A CN106036880A CN 106036880 A CN106036880 A CN 106036880A CN 201610547438 A CN201610547438 A CN 201610547438A CN 106036880 A CN106036880 A CN 106036880A
- Authority
- CN
- China
- Prior art keywords
- powder
- parts
- dysmenorrhea
- composition
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010013935 Dysmenorrhoea Diseases 0.000 title claims abstract description 53
- 208000005171 Dysmenorrhea Diseases 0.000 title claims abstract description 48
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 235000001497 healthy food Nutrition 0.000 title abstract 2
- 239000000843 powder Substances 0.000 claims abstract description 102
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 28
- 235000000346 sugar Nutrition 0.000 claims abstract description 22
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 20
- 239000011707 mineral Substances 0.000 claims abstract description 20
- 150000003839 salts Chemical class 0.000 claims abstract description 18
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 17
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 17
- 235000008434 ginseng Nutrition 0.000 claims abstract description 17
- 108010010803 Gelatin Proteins 0.000 claims abstract description 15
- 239000008273 gelatin Substances 0.000 claims abstract description 15
- 229920000159 gelatin Polymers 0.000 claims abstract description 15
- 235000019322 gelatine Nutrition 0.000 claims abstract description 15
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 15
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229960000304 folic acid Drugs 0.000 claims abstract description 14
- 235000019152 folic acid Nutrition 0.000 claims abstract description 14
- 239000011724 folic acid Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 18
- 210000000481 breast Anatomy 0.000 claims description 18
- 235000013402 health food Nutrition 0.000 claims description 18
- 241000208340 Araliaceae Species 0.000 claims description 16
- SRFKWQSWMOPVQK-UHFFFAOYSA-K sodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate;iron(2+) Chemical compound [Na+].[Fe+2].OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O SRFKWQSWMOPVQK-UHFFFAOYSA-K 0.000 claims description 15
- 239000000284 extract Substances 0.000 claims description 14
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 13
- 239000011575 calcium Substances 0.000 claims description 13
- 229910052791 calcium Inorganic materials 0.000 claims description 13
- 241001145025 Saussurea involucrata Species 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 10
- 235000013361 beverage Nutrition 0.000 claims description 8
- 239000007787 solid Substances 0.000 claims description 7
- 239000002552 dosage form Substances 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 21
- 235000013305 food Nutrition 0.000 abstract description 13
- 239000000463 material Substances 0.000 abstract description 6
- 239000003755 preservative agent Substances 0.000 abstract description 4
- 230000002335 preservative effect Effects 0.000 abstract description 4
- 239000000654 additive Substances 0.000 abstract description 2
- 235000013336 milk Nutrition 0.000 abstract description 2
- 239000008267 milk Substances 0.000 abstract description 2
- 210000004080 milk Anatomy 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 241000283074 Equus asinus Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 241000133134 Saussurea Species 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 235000017803 cinnamon Nutrition 0.000 abstract 1
- 235000013312 flour Nutrition 0.000 abstract 1
- 229940002508 ginger extract Drugs 0.000 abstract 1
- 235000020708 ginger extract Nutrition 0.000 abstract 1
- MKWYFZFMAMBPQK-UHFFFAOYSA-J sodium feredetate Chemical compound [Na+].[Fe+3].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O MKWYFZFMAMBPQK-UHFFFAOYSA-J 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 23
- 210000004369 blood Anatomy 0.000 description 22
- 235000010755 mineral Nutrition 0.000 description 16
- 208000002193 Pain Diseases 0.000 description 12
- 230000007812 deficiency Effects 0.000 description 8
- 241000282414 Homo sapiens Species 0.000 description 7
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
- 108010052008 colla corii asini Proteins 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 229910052742 iron Inorganic materials 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000011734 sodium Substances 0.000 description 5
- 229910052708 sodium Inorganic materials 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 206010047700 Vomiting Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 231100000957 no side effect Toxicity 0.000 description 4
- 230000027758 ovulation cycle Effects 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 239000011573 trace mineral Substances 0.000 description 4
- 235000013619 trace mineral Nutrition 0.000 description 4
- 230000008673 vomiting Effects 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 201000000736 Amenorrhea Diseases 0.000 description 3
- 206010001928 Amenorrhoea Diseases 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 231100000540 amenorrhea Toxicity 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 230000003821 menstrual periods Effects 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 239000008108 microcrystalline cellulose Substances 0.000 description 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 3
- 229940016286 microcrystalline cellulose Drugs 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 239000003826 tablet Substances 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 241000167854 Bourreria succulenta Species 0.000 description 2
- 244000060011 Cocos nucifera Species 0.000 description 2
- 235000013162 Cocos nucifera Nutrition 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- 208000010228 Erectile Dysfunction Diseases 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 239000005862 Whey Substances 0.000 description 2
- 102000007544 Whey Proteins Human genes 0.000 description 2
- 108010046377 Whey Proteins Proteins 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000000146 antalgic effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 235000019693 cherries Nutrition 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 2
- ZOOGRGPOEVQQDX-UHFFFAOYSA-N cyclic GMP Natural products O1C2COP(O)(=O)OC2C(O)C1N1C=NC2=C1NC(N)=NC2=O ZOOGRGPOEVQQDX-UHFFFAOYSA-N 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000008451 emotion Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 239000000576 food coloring agent Substances 0.000 description 2
- 235000013355 food flavoring agent Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- NLDDIKRKFXEWBK-AWEZNQCLSA-N gingerol Chemical compound CCCCC[C@H](O)CC(=O)CCC1=CC=C(O)C(OC)=C1 NLDDIKRKFXEWBK-AWEZNQCLSA-N 0.000 description 2
- JZLXEKNVCWMYHI-UHFFFAOYSA-N gingerol Natural products CCCCC(O)CC(=O)CCC1=CC=C(O)C(OC)=C1 JZLXEKNVCWMYHI-UHFFFAOYSA-N 0.000 description 2
- 235000002780 gingerol Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000000314 lubricant Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 150000003505 terpenes Chemical class 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- JVXHQHGWBAHSSF-UHFFFAOYSA-L 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydron;iron(2+) Chemical compound [H+].[H+].[Fe+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O JVXHQHGWBAHSSF-UHFFFAOYSA-L 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- 229940090248 4-hydroxybenzoic acid Drugs 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010054196 Affect lability Diseases 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 108010011485 Aspartame Proteins 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- SEBIKDIMAPSUBY-ARYZWOCPSA-N Crocin Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)C(C)=CC=CC(C)=C\C=C\C=C(/C)\C=C\C=C(C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O1)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SEBIKDIMAPSUBY-ARYZWOCPSA-N 0.000 description 1
- IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 201000009273 Endometriosis Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000004356 Hysteria Diseases 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- 206010022971 Iron Deficiencies Diseases 0.000 description 1
- XINCECQTMHSORG-UHFFFAOYSA-N Isoamyl isovalerate Chemical compound CC(C)CCOC(=O)CC(C)C XINCECQTMHSORG-UHFFFAOYSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- NBGXQZRRLOGAJF-UHFFFAOYSA-N Maltulose Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)(CO)OCC1O NBGXQZRRLOGAJF-UHFFFAOYSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- SBDNJUWAMKYJOX-UHFFFAOYSA-N Meclofenamic Acid Chemical compound CC1=CC=C(Cl)C(NC=2C(=CC=CC=2)C(O)=O)=C1Cl SBDNJUWAMKYJOX-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- KWKVAGQCDSHWFK-VNKDHWASSA-N Methyl sorbate Chemical compound COC(=O)\C=C\C=C\C KWKVAGQCDSHWFK-VNKDHWASSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 239000004376 Sucralose Substances 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 244000126002 Ziziphus vulgaris Species 0.000 description 1
- ZQBZAOZWBKABNC-UHFFFAOYSA-N [P].[Ca] Chemical compound [P].[Ca] ZQBZAOZWBKABNC-UHFFFAOYSA-N 0.000 description 1
- 206010000059 abdominal discomfort Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 239000000605 aspartame Substances 0.000 description 1
- 235000010357 aspartame Nutrition 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
- 229960003438 aspartame Drugs 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013522 chelant Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 208000012839 conversion disease Diseases 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 229940109262 curcumin Drugs 0.000 description 1
- 235000012754 curcumin Nutrition 0.000 description 1
- 239000004148 curcumin Substances 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 description 1
- 229960001259 diclofenac Drugs 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000002183 duodenal effect Effects 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 1
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000009627 gardenia yellow Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 description 1
- 229960000991 ketoprofen Drugs 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- JCQLYHFGKNRPGE-HFZVAGMNSA-N maltulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-HFZVAGMNSA-N 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 229960003803 meclofenamic acid Drugs 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229930189775 mogroside Natural products 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229940127234 oral contraceptive Drugs 0.000 description 1
- 239000003539 oral contraceptive agent Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 229940068041 phytic acid Drugs 0.000 description 1
- 239000000467 phytic acid Substances 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000001253 polyvinylpolypyrrolidone Substances 0.000 description 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 239000004300 potassium benzoate Substances 0.000 description 1
- 235000010235 potassium benzoate Nutrition 0.000 description 1
- 229940103091 potassium benzoate Drugs 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 208000018299 prostration Diseases 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- NIFIFKQPDTWWGU-UHFFFAOYSA-N pyrite Chemical class [Fe+2].[S-][S-] NIFIFKQPDTWWGU-UHFFFAOYSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 229920006300 shrink film Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical group [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229960003885 sodium benzoate Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 229940091252 sodium supplement Drugs 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- QJVXKWHHAMZTBY-GCPOEHJPSA-N syringin Chemical compound COC1=CC(\C=C\CO)=CC(OC)=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 QJVXKWHHAMZTBY-GCPOEHJPSA-N 0.000 description 1
- QJVXKWHHAMZTBY-KSXIZUIISA-N syringin Natural products COc1cc(C=CCO)cc(OC)c1O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O QJVXKWHHAMZTBY-KSXIZUIISA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 235000021404 traditional food Nutrition 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical group [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composition for relieving dysmenorrhea, application thereof and healthy food prepared from the composition. The composition for relieving dysmenorrhea is prepared from, by weight, 50-80 parts of brown powdered sugar, 2-8 parts of instant donkey hide gelatin powder, 1-4 parts of fresh ginger extract, 0.08-3 parts of EDTA ferric sodium salt, 1-5 parts of ginseng powder, 1-10 parts of milk mineral salt, 1-5 parts of hawthorn powder, 1-5 parts of yam flour, 2-10 parts of red date powder, 0.1-3 parts of cinnamon powder, 0.05-3 parts of saussurea involucrate culture and 0.0001-0.0005 part of folic acid. According to the formula of the composition, food raw materials are adopted as materials, original ecology is kept, no preservative or fresh keeping agent or other additives are added, the composition is safe to eat, and has no obvious adverse reactions or toxic and side effects after being taken for a long time, and it is proved through the crowd test that the composition has a remarkable effect of relieving dysmenorrhea after being taken.
Description
Technical field
The present invention relates to field of food, be specifically related to a kind of compositions alleviating dysmenorrhea and application thereof and be made from strong
Health food.
Background technology
Primary dysmenorrhea refer to mature women be expert at through front and back or menstrual period occur stomachache, the soreness of waist, lower abdomen falling inflation or its
He is uncomfortable.Modern popular disease research shows, the prevalence of dysmenorrhea is 33-90%, has a strong impact on the live and work of women.
The method of existing treatment dysmenorrhea mostly is Drug therapy, mainly includes that (1) takes PGSI, as
Conventional medicine has ibuprofen, ketoprofen, meclofenamic acid, diclofenac etc.;(2) take oral contraceptive and (be applicable to requirement
The dysmenorrhea women of contraception).Both the above types of drug all has a more contraindication, and with gastrointestinal upset etc. many bad instead
Should.
Along with the quickening day by day of modern society's rhythm of life, easy to carry and use and long-term taking has no side effect safely
Product increasingly favored.Health food is the one of food, has the general character of normal food, and its raw material is mainly taken from
Natural animals and plants, through modernization vanguard technology, are fabricated to the dosage form food such as tablet, granule, powder, capsule, phase
For traditional food, it is aesthetic in appearance, carry with instant, be eaten for a long time safety and have no side effect, the modern day for human beings can be met
Normal allegro life and health demand.
Therefore, for the dysmenorrhea of women, develop a kind of health food alleviating dysmenorrhea and have important practical significance.
Summary of the invention
In consideration of it, the primary and foremost purpose of the present invention is to provide a kind of compositions alleviating dysmenorrhea, said composition has substantially
Alleviate the effect of dysmenorrhea, and edible safety, have no side effect.
Another object of the present invention is to the compositions that above-mentioned alleviation dysmenorrhea is provided in dysmenorrhea health food is alleviated in preparation
Application.
It is still another object of the present invention to provide the health food of the compositions comprising above-mentioned alleviation dysmenorrhea.
The present invention is to be achieved through the following technical solutions:
A kind of compositions alleviating dysmenorrhea, is made up of the raw material of following portions by weight:
Brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens extract 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part,
Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, Rhizoma Dioscoreae powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder
0.1-3 part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
Preferably, the compositions of alleviation dysmenorrhea of the present invention, it is made up of the raw material of following portions by weight:
Brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6 part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng
Powder 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4 part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, snow
Lotus culture 0.5-1.5 part, folic acid 0.0002-0.0004 part.
Brown powdered sugar has QI invigorating, helps spleen relieving dyspepsia, effects such as blood stasis dispelling of enriching blood, and also has dispersing cold for relieving pain effect concurrently.So, Nv Xingyin
Catch cold, diseases such as unfavorable, dysmenorrhea, the dark red double abdomen cold type of pain of menstruation of passing through caused by blood stasis, drinking a little brown sugar water, often to play treatment gentle
Solution effect.Glucose contained by brown sugar releases energy soon, and absorption rate is high, can quickly regain one's strength of body.Brown sugar contains
Abundant calcium and ferrum, and calcium and ferrum are mineral and the trace element of needed by human.The traditional Chinese medical science think brown sugar by " temperature and mend it,
Wen Ertong it, temperature and dissipate it " and play blood tonification effect.
Instant ass-hide gelatin powder be by Colla Corii Asini through dispensing, dry, pulverize, stir, mix, the processes such as metering, distributing, packaging, packaging
Make, there is enriching blood, stop blooding, clearing away lung-heat and moistening for dryness, control cough, control diarrhoea, beauty treatment effect such as hair care.Colla Corii Asini is by collagen protein group
Becoming, its hydrolysis can obtain protein, polypeptide and several amino acids.Containing substantial amounts of aminoacid and trace element in Colla Corii Asini, these are all
It is leukocyte and the synthesis material of hemoglobin and regulation factor.So, take Colla Corii Asini and contribute to preventing anemia, can help lean
Blood, the person of losing blood get well.
Rhizoma Zingiberis Recens extract extracts from Rhizoma Zingiberis Recens, and it mainly comprises volatile oil and gingerol, has relieving exterior syndrome and dispelling cold, warming middle-JIAO
Preventing or arresting vomiting, the effect such as preventing phlegm from forming and stopping coughing, for anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough etc..Its distinctive " gingerol " can stimulate stomach
Intestinal mucosa, makes gastrointestinal redness, and digestion power strengthens, can effectively treat eat cold and cool food and too much cause abdominal distention, stomachache,
Diarrhoea, vomiting etc..
Sodium iron ethylenediaminetetraacetate is a kind of iron enriched nutrient, and iron-holder is about 12-14%, sodium iron ethylenediaminetetraacetate
For stable chelate, non-stimulated to gastrointestinal, there is special duodenal absorption, be tightly combined under one's belt, enter duodenum
After, ferrum is just released and absorbs, and its absorbance is high, is avoided that the obstacle that chalybeate is absorbed by phytic acid etc., EDTA in absorption process
Also can be combined excretion rapidly with harmful element and play the effect of antidote.Sodium iron ethylenediaminetetraacetate have promotion meals in its
The effect that his source of iron or endogenous source of iron absorb, may additionally facilitate the absorption of zinc simultaneously, and on the absorption of calcium without impact.
Radix Ginseng powder is the powder made for raw material with Radix Ginseng, and Radix Ginseng belongs to integration of edible and medicinal herbs food, and pharmacopeia records it can complement greatly
Gas, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid and nourishes blood, Fructus Alpiniae Oxyphyllae of calming the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed heavily
Coughing, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, and prolonged illness void is won, palpitation with fear insomnia, sexual impotence cold womb.
Breast mineral salt belongs to new resource food, has another name called milk calcium, whey mineral concentrate, whey calcium, derives from Lac Bovis seu Bubali, be
By Lac Bovis seu Bubali by membrane permeation, the off-white powder that separates, concentrate and obtain after the PROCESS FOR TREATMENT such as spray drying, its main component is
Calcium phosphate, the most also includes the nutritional labeling that protein, lactose and zinc, phosphorus, sodium, potassium, magnesium etc. are abundant, and calcium content is about
23%~28%, its calcium-phosphorus ratio is 2: 1, more beneficially the absorbing of human body.Breast mineral salt not only can supplement the absorption of calcium, also
The health-care effect such as reduce blood pressure, prevent arteries narrow.
The powder that Fructus Crataegi powder is made up of Fructus Crataegi, have removing food stagnancyization stagnant, convergence the effect such as dysentery relieving, activating blood circulation to dissipate blood stasis, cure mainly diet
The diseases such as stagnant, chest and diaphragm feeling of fullness, hernia blood stasis amenorrhea, containing the ingredient such as mountain terpenoid and pyrite class in Fructus Crataegi, have significantly
Expansion blood vessel and hypotensive effect, have enhancing cardiac muscle, arrhythmia, regulation blood fat and the function of cholesterol level, be used for treating
Coronary heart disease, hypertension, hyperlipidemia etc., it addition, Fructus Crataegi also has function of promoting blood circulation to disperse blood clots, be that the dietetic therapy of blood stasis type dysmenorrhea patient is good
Product.
The powdery that Rhizoma Dioscoreae powder is made with Rhizoma Dioscoreae, has spleen invigorating QI invigorating, and lung benefiting reinforces the kidney, the effect such as blood fat reducing, the intestines and stomach coordinating,
Rhizoma Dioscoreae contains soluble fiber, can postpone the emptying of gastric food, controls blood glucose after meal and raises.Can also aid digestion, blood sugar lowering.Control
Feed processed is intended to as high-nutrition food, containing compositions such as protein, saccharide, vitamin, fat, choline, amylase in Rhizoma Dioscoreae, also
Containing the indispensable inorganic salt of human body and trace element such as iodine, calcium, ferrum, phosphorus.
Red date powder contains various bioactivators, as jujube polysaccharide, flavonoid, saponins, triterpenes, alkaloids,
Adenosine cyclophosphate, cyclic GMP concentration (cGMP) etc., have plurality kinds of health care to cure the disease effect to human body.It is mainly used in deficiency of QI in middle-JIAO, taste void
The treatment of the card such as weak, fatigue and asthenia, anorexia and loose stool, blood deficiency and yellow complexion, women's hysteria.
Cortex Cinnamomi powder is the powder made for raw material with Cortex Cinnamomi, and Cortex Cinnamomi belongs to integration of edible and medicinal herbs food, and pharmacopeia is recorded it and can be mended fire and help
Sun, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.For sexual impotence cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, upward floating of YANG in deficiency condition, dizziness mesh
Red, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, colic of cold type stomachache, dysmenorrhea amenorrhea.
Saussurea involucrata culture is to choose Herba Saussureae Involueratae callus as subculture seed, is obtained by cell culture technology successive transfer culture
, Saussurea involucrata culture contains the multiple active ingredients such as flavone, polysaccharide, chlorogenic acid, syringoside, trace element and terpenoid, has
Dispelling cold and removing dampness, effect such as dysmenorrhea, anti-inflammatory and antalgic of invigorating blood circulation, be used for treating rheumatic arthritis, women's cold and pain in the lower abdomen, amenorrhea, paralysis
The disease such as impermeable.
Folic acid is a kind of water soluble vitamins, for the necessary material of body cell growth and breeding, helps protein
Metabolism, and collectively promote erythrocytic generation and maturation with vitamin B12, it is to manufacture the indispensable material of erythrocyte.
The present invention uses Rhizoma Zingiberis Recens extract relieving exterior syndrome and dispelling cold, Radix Ginseng powder's strongly invigorating primordial QI, the yang-energy of reinforcing the heart, and Cortex Cinnamomi powder complement is positive,
Except cold long-pending, warm passages through which vital energy circulates internal organs, release the various pain caused because of cold-evil, red date powder, Rhizoma Dioscoreae powder, instant ass-hide gelatin powder spleen invigorating benefit
Stomach, vigorate qi and replenish the blood, brown powdered sugar can supplement rapidly energy to body, and QI and blood abundance can be beneficial to cold and discharges and release pain, Fructus Crataegi
Powder, Saussurea involucrata culture can go silt to invigorate blood circulation, anti-inflammatory and antalgic, then are aided with sodium iron ethylenediaminetetraacetate, breast mineral salt and folic acid, supplement people
Ferrum needed for body, calcium etc., full side Synergistic, promoting flow of QI and blood, dispersing cold for relieving pain, up to warming up, invigorating spleen and reinforcing stomach, the alleviation dysmenorrhea of dispeling cold
Effect.
The compositions that present invention also offers above-mentioned alleviation dysmenorrhea is preparing the application alleviated in dysmenorrhea health food, and this delays
Solve the compositions of dysmenorrhea, be made up of the raw material of following portions by weight: brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens carry
Take thing 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part, Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, mountain
Medicated powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder 0.1-3 part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
Preferably, the proportioning raw materials of the compositions of this alleviation dysmenorrhea is as follows: brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6
Part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng powder's 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4
Part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, Saussurea involucrata culture 0.5-1.5 part, folic acid 0.0002-0.0004
Part.
Dysmenorrhea of the present invention is primary dysmenorrhea.
Present invention also offers a kind of health food, comprise in compositions and the bromatology of the alleviation dysmenorrhea that the present invention provides
Acceptable adjuvant.
In bromatology of the present invention acceptable adjuvant can be selected from filler, lubricant, Fruit powder, edible essence,
The mixing of one or more in sweeting agent, acidic flavoring agent, preservative, food coloring, disintegrating agent.
Described filler can be starch, Icing Sugar, dextrin, microcrystalline Cellulose, mannitol, lactose, pregelatinized Starch or different
One or more in maltulose alcohol;
Described disintegrating agent can be dried starch, carboxymethylstach sodium, low-substituted hydroxypropyl cellulose, polyvinylpolypyrrolidone, crosslinking carboxylic first
One or more in base Starch Sodium or cross-linking sodium carboxymethyl cellulose;
Described lubricant can be one or more in magnesium stearate, micropowder silica gel, Polyethylene Glycol or Pulvis Talci;
Described Fruit powder can be one or more in orange powder, orange powder, Fructus Citri Limoniae powder, cherry powder, apple powder or coconut palm powder;
Described edible essence can be that flavoring orange essence, orange essence, Fructus Citri Limoniae essence, cherry essence, Mentholum, apple essence or coconut palm are fragrant
One or more in essence;
Described sweeting agent is one or more in sucralose, AK sugar, aspartame or mogroside;
Described acidic flavoring agent is one or more in malic acid, lactic acid or citric acid;
Described preservative is sodium benzoate, Potassium Benzoate, sorbic acid methyl ester, ethylparaben or P-hydroxybenzoic acid benzene
One or more in ester;
Described food coloring is one or more in burnt sugar coloring, Gardenia Yellow, curcumin or chlorophyll.
The dosage form of health food of the present invention can be solid beverage, tablet, granule or capsule, its preparation method
Conventional method is used to prepare.Only need brewed in hot water due to solid beverage, Instant Drinks convenience, independent packaging, be easy to carry, because of
The dosage form of this health food of the present invention is preferably solid beverage.
The present invention compared with prior art, has the advantages that
(1) formula of the present composition is all with raw-food material as material, keep ecosystem, without any preservative,
The additives such as antistaling agent, edible safety, long-term taking, without obvious untoward reaction and toxic and side effects, tests table through crowd
Bright, take this product and there is the effect significantly alleviating dysmenorrhea;
(2) menstrual phase, because internal endocrine change and the contraction in uterus, for calcareous increase in demand, when internal calcium
During content deficiency, emotional instability will be caused, the spasm phenomenon such as organ ache also or in pelvic cavity, the therefore present invention
In formula, with the addition of breast mineral salt reach releive blood vessel, the deflation situation of muscle and loosen the effect of emotion as calcium source;
It addition, women has universality iron deficiency problem mostly, when menstruation, can make because haemachrome synthesis is not enough and oxygen carrying content is inadequate
Complexion is turned white, QI and blood has some setbacks, related impact individual emotion, vigor and memory, therefore the present invention adds second in formula
Ethylenediamine tetraacetic acid (EDTA) ferrum sodium supplements " irony " of needed by human body as source of iron;Calcium source, source of iron and other raw material Synergistics in formula,
Produce the effect significantly alleviating dysmenorrhea.
Detailed description of the invention
Further illustrating the present invention below by detailed description of the invention, following example are the present invention preferably embodiment party
Formula, but embodiments of the present invention are not limited by following embodiment.
The raw material that the embodiment of the present invention is used is as follows:
Instant ass-hide gelatin powder: Donga, Shandong Dongsheng Colla Corii Asini product technology development corporation, Ltd.;Rhizoma Zingiberis Recens extract: commercially available;Ethylenediamine tetraacetic
Acetic acid ferrum sodium: Zhengzhou Ruipu Bioengineering Co., Ltd.;Radix Ginseng powder: commercially available;Breast mineral salt: Holland U.S. element (Frieslan
Campina);Saussurea involucrata culture: Dalian Puruikang Biotechnology Co;Folic acid: DSM N. V.;Fructus Crataegi powder: commercially available;
Rhizoma Dioscoreae powder: commercially available;Red date powder: Tianjin is just like fruit food industry company limited;Cortex Cinnamomi powder: commercially available.
Embodiment 1 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 50 parts, instant ass-hide gelatin powder 8 parts, Rhizoma Zingiberis Recens extract 1 part, sodium iron ethylenediaminetetraacetate 0.08
Part, Radix Ginseng powder 5 parts, breast mineral salt 1 part, Fructus Crataegi powder 5 parts, Rhizoma Dioscoreae powder 5 parts, red date powder 10 parts, Cortex Cinnamomi powder 0.1 part, Herba Saussureae Involueratae
Culture 0.05 part, 0.0005 part of folic acid mix and get final product.
Embodiment 2 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3 parts, sodium iron ethylenediaminetetraacetate 2 parts, Radix Ginseng powder 3
Part, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts, Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1 part, folic acid
0.0003 part mixes and get final product.
Embodiment 3 alleviates the preparation of the compositions of dysmenorrhea
By brown powdered sugar 80 parts, instant ass-hide gelatin powder 2 parts, Rhizoma Zingiberis Recens extract 4 parts, sodium iron ethylenediaminetetraacetate 3 parts, Radix Ginseng powder 1
Part, breast mineral salt 10 parts, Fructus Crataegi powder 1 part, Rhizoma Dioscoreae powder 1 part, red date powder 2 parts, Cortex Cinnamomi powder 3 parts, Saussurea involucrata culture 3 parts, leaf
Acid 0.0001 part mixes and get final product.
The preparation of embodiment 4 health food solid beverage
The compositions of alleviation dysmenorrhea: brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3 parts, sodium iron ethylenediaminetetraacetate
2 parts, Radix Ginseng powder 3 parts, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts, Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1
Part, 0.0003 part of folic acid.
Preparation technology: by above-mentioned raw materials granulation, granulate, mix, enter bag, mounted box, shrink film make finished product.
The preparation of embodiment 5 health food tablet
The compositions of alleviation dysmenorrhea: the compositions of alleviation dysmenorrhea: brown powdered sugar 60 parts, instant ass-hide gelatin powder 6 parts, Rhizoma Zingiberis Recens extract 3
Part, sodium iron ethylenediaminetetraacetate 2 parts, Radix Ginseng powder 3 parts, breast mineral salt 6 parts, Fructus Crataegi powder 3 parts, Rhizoma Dioscoreae powder 3 parts, red date powder 6 parts,
Cortex Cinnamomi powder 2 parts, Saussurea involucrata culture 1 part, 0.0003 part of folic acid.
Adjuvant: microcrystalline Cellulose 10 parts, Sorbitol 5 parts.
Preparation technology: the compositions of dysmenorrhea, microcrystalline Cellulose, Sorbitol mix homogeneously, tabletting will be alleviated, be distributed into bottle
?.
The beneficial effect of of the present invention prescription is expanded on further by human experiment data.
One, clinical case: 50 example dysmenorrhea patients.All meet following diagnostic criteria:
1. genitals is without significant organic pathological changes person.
2. cardinal symptom: with cold-type pain in the lower abdomen during menstruation falling inflation before and after passing through.
3. simultaneous phenomenon: dark through the few color of blood volume, distending pain of the breast, it to be afraid of cold, profuse leukorrhea, color is white.
4. general malaise: waist is ached, rectal tenesmus, dizzy weak, occur time serious that complexion is turned white perspiration, even suffer a shock
Etc. general malaise symptom.
Age 18-48 year.
All cases is primary dysmenorrhea, gets rid of the cause of disease of secondary dysmenorrhea, endometriosis, urgent chronic pelvic inflammatory disease
Or cervical stenosis obstruction etc..
All cases is divided into two groups, is 1 menstrual cycle Experiment on therapy group, 1 menstrual cycle treatment matched group respectively.Often
Organize 25 examples, two groups of case no significant differences in terms of age, the course of disease and the state of an illness.
Two, Therapeutic Method:
1, experimental group: the solid beverage of embodiment 4, oral, take 1 bag (8g) 30 ~ 60 minutes ante cibum at ordinary times, during pain in menstrual period, drink 1
~ 2 bags, 1 month are a course for the treatment of.
Matched group: happy redTMColla Corii Asini beverage (celestial happy health), oral, take 1 bottle (8g) 30 ~ 60 minutes ante cibum at ordinary times, menstrual period ache
Drink 1 ~ 2 bottle time bitterly, within 1 month, be a course for the treatment of.
2, points for attention: hyperglycemia, hyperpietic are cautious use of.
Three, efficacy assessment standard:
Cure: after treatment, symptom all disappears, and intermenstrual period is without significant discomfort;
Take a turn for the better: after treatment, symptom is obviously improved, occasionally have dysmenorrhea, more slightly;
Invalid: before and after treatment, symptom is not improved.
Four, therapeutic effect:
Taking experimental group 25 example of 1 menstrual cycle, healing is 22 examples, transfers well 2 examples to;Invalid 1 example, total effective rate is 96%;
Taking matched group 25 example of 1 menstrual cycle, healing is 15 examples, transfers well 3 examples to;Invalid 7 examples, total effective rate is 72%;Two groups total
Effective percentage compares, and experimental group is substantially better than matched group.
Safety observations: do not find any untoward reaction, have no side effect.
Claims (9)
1. the compositions alleviating dysmenorrhea, it is characterised in that be made up of the raw material of following portions by weight:
Brown powdered sugar 50-80 part, instant ass-hide gelatin powder 2-8 part, Rhizoma Zingiberis Recens extract 1-4 part, sodium iron ethylenediaminetetraacetate 0.08-3 part,
Radix Ginseng powder's 1-5 part, breast mineral salt 1-10 part, Fructus Crataegi powder 1-5 part, Rhizoma Dioscoreae powder 1-5 part, red date powder 2-10 part, Cortex Cinnamomi powder 0.1-3
Part, Saussurea involucrata culture 0.05-3 part, folic acid 0.0001-0.0005 part.
The compositions of alleviation dysmenorrhea the most according to claim 1, it is characterised in that by the raw material system of following portions by weight
Become:
Brown powdered sugar 60-70 part, instant ass-hide gelatin powder 4-6 part, Rhizoma Zingiberis Recens extract 2-3 part, sodium iron ethylenediaminetetraacetate 1-2 part, Radix Ginseng
Powder 2-4 part, breast mineral salt 4-7 part, Fructus Crataegi powder 2-4 part, Rhizoma Dioscoreae powder 2-4 part, red date powder 4-7 part, Cortex Cinnamomi powder 1-2 part, Herba Saussureae Involueratae training
Support thing 0.5-1.5 part, folic acid 0.0002-0.0004 part.
The compositions of alleviation dysmenorrhea the most according to claim 1 and 2, it is characterised in that described sodium iron ethylenediaminetetraacetate
The weight content of middle ferrum is 12-14%.
The compositions of alleviation dysmenorrhea the most according to claim 1 and 2, it is characterised in that the weight of calcium in described breast mineral salt
Amount content is 23-28%.
5. the compositions of the alleviation dysmenorrhea described in any one of claim 1-4 application in dysmenorrhea health food is alleviated in preparation.
Application the most according to claim 5, it is characterised in that described dysmenorrhea is primary dysmenorrhea.
7. a health food, the compositions comprising the alleviation dysmenorrhea described in any one of claim 1-4 and bromatology can connect
The adjuvant being subject to.
Health food the most according to claim 7, it is characterised in that the dosage form of described health food is solid beverage, sheet
Agent, granule or capsule.
Health food the most according to claim 8, it is characterised in that the dosage form of described health food is solid beverage.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610547438.0A CN106036880B (en) | 2016-07-13 | 2016-07-13 | A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610547438.0A CN106036880B (en) | 2016-07-13 | 2016-07-13 | A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106036880A true CN106036880A (en) | 2016-10-26 |
CN106036880B CN106036880B (en) | 2019-03-22 |
Family
ID=57186693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610547438.0A Active CN106036880B (en) | 2016-07-13 | 2016-07-13 | A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106036880B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107510052A (en) * | 2017-08-25 | 2017-12-26 | 广西南宁华鑫糖业技术有限责任公司 | A kind of combination product for alleviating dysmenorrhoea and beauty and preparation method thereof |
CN109527568A (en) * | 2018-11-05 | 2019-03-29 | 天津国民健康技术有限公司 | A kind of functional food and preparation method thereof improving blood stasis constitution |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101548738A (en) * | 2008-03-31 | 2009-10-07 | 上海怡神保健食品有限公司 | Jujube brown sugar and preparation method thereof |
CN101700136A (en) * | 2009-11-17 | 2010-05-05 | 晋城市阿拉丁饮品厂 | Ginger, brown sugar and hawthorn compound beverage and preparation method thereof |
CN102366432A (en) * | 2011-11-02 | 2012-03-07 | 大连普瑞康生物技术有限公司 | Saussurea involucrata culture extract and novel purpose thereof |
CN102895410A (en) * | 2012-09-10 | 2013-01-30 | 青岛广昭国际贸易有限公司 | Health-strengthening donkey-hide gelatin jelly for females |
CN103251899A (en) * | 2013-04-22 | 2013-08-21 | 山东大学齐鲁医院 | Oral drug for treating dysmenorrhea |
CN103845348A (en) * | 2012-11-30 | 2014-06-11 | 富力 | Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating dysmenorrhea |
-
2016
- 2016-07-13 CN CN201610547438.0A patent/CN106036880B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101548738A (en) * | 2008-03-31 | 2009-10-07 | 上海怡神保健食品有限公司 | Jujube brown sugar and preparation method thereof |
CN101700136A (en) * | 2009-11-17 | 2010-05-05 | 晋城市阿拉丁饮品厂 | Ginger, brown sugar and hawthorn compound beverage and preparation method thereof |
CN102366432A (en) * | 2011-11-02 | 2012-03-07 | 大连普瑞康生物技术有限公司 | Saussurea involucrata culture extract and novel purpose thereof |
CN102895410A (en) * | 2012-09-10 | 2013-01-30 | 青岛广昭国际贸易有限公司 | Health-strengthening donkey-hide gelatin jelly for females |
CN103845348A (en) * | 2012-11-30 | 2014-06-11 | 富力 | Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating dysmenorrhea |
CN103251899A (en) * | 2013-04-22 | 2013-08-21 | 山东大学齐鲁医院 | Oral drug for treating dysmenorrhea |
Non-Patent Citations (6)
Title |
---|
刘申锡: "《妇科内分泌治疗手册》", 31 July 1957, 上海卫生出版社 * |
吉鹤立: "《中国食品添加剂及配料手册》", 30 June 2016, 中国质检出版社 * |
王小荣: "肉桂油治疗原发性痛经的机理研究", 《中国中医药杂志》 * |
相国庆: "《轻松度过经期那几天》", 30 April 2015, 金盾出版社 * |
臧峻岐: "《膳食内调,穴位外治月经不调》", 30 April 2016, 黑龙江科学技术出版社 * |
郭本恒: "《干酪科学与技术》", 31 May 2015, 中国轻工业出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107510052A (en) * | 2017-08-25 | 2017-12-26 | 广西南宁华鑫糖业技术有限责任公司 | A kind of combination product for alleviating dysmenorrhoea and beauty and preparation method thereof |
CN109527568A (en) * | 2018-11-05 | 2019-03-29 | 天津国民健康技术有限公司 | A kind of functional food and preparation method thereof improving blood stasis constitution |
Also Published As
Publication number | Publication date |
---|---|
CN106036880B (en) | 2019-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102178884B (en) | Chinese medicine preparation for regulating weakness of spleen and stomach of people with deficiency of vital energy, preparation method and application thereof | |
CN100584210C (en) | Growth accelerating agent for pigs made from Chinese herb medicines, and its preparation method | |
CN103690919B (en) | Medicine being used for the treatment of piglet iron-deficiency anemia and preparation method thereof | |
CN104431586A (en) | Piglet compound feed and preparation method thereof | |
CN104873763A (en) | Health-care product for conditioning Qi deficiency constitution | |
CN103007107B (en) | Chinese medicinal preparation for regulating postpartum frail | |
CN103989045A (en) | Brown sugar composition for menstrual period and application thereof | |
CN103431276A (en) | Mixed-grain total-nutrition formulation food for patients with inflammatory bowel diseases | |
CN100431568C (en) | Chinese medicine for treating puerperal hypogalactia | |
CN106036880B (en) | A kind of composition and its application and the healthy food being made from it for alleviating dysmenorrhea | |
CN103431260A (en) | Mixed-grain full-nutrition formulation food for patients with gastrointestinal tract malabsorption and pancreatitis | |
CN104839704A (en) | Yang invigorating non-total nutrient formula food | |
CN104524358A (en) | Pills for adjuvant treatment of iron-deficiency anemia and preparation method thereof | |
CN104906526A (en) | Chinese medicine preparation for premature ovarian failure and preparation method of Chinese medicine preparation | |
CN104689067A (en) | Traditional Chinese medicine composition for treating sexual precocity and application thereof | |
CN100431584C (en) | Chinese medicinal formulation for caring and enlarging breast | |
CN104687137A (en) | Formula and production method of pilose antler brain-strengthening nerves-calming soup material | |
CN103272147A (en) | Traditional Chinese medicine preparation for curing vomiting of pregnancy | |
CN107898990A (en) | A kind of Chinese medicine preparation for treating neurosis and preparation method thereof | |
CN101019979B (en) | Lactation promoting health product | |
CN106389748A (en) | Traditional Chinese herbal compound for promoting postpartum lactating of livestock and preparation method thereof | |
CN101020041A (en) | Antilipemic health product | |
CN104940777A (en) | Electuary capable of treating liver-yang hyperactivity and spleen weakness type diarrhea during menstruation and preparation method thereof | |
CN105395850A (en) | Medicine for replenishing blood and tonifying Qi and health care product | |
CN104784587A (en) | Traditional Chinese medicine composition for treating endocrine disorder type infertility and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |