CN105395850A - Medicine for replenishing blood and tonifying Qi and health care product - Google Patents
Medicine for replenishing blood and tonifying Qi and health care product Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine health care product for replenishing blood and tonifying Qi. The traditional Chinese medicine health care product is prepared from American ginseng, rhizoma atractylodis macrocephalae, Chinese dates, prepared rehmannia roots, arillus longan, radix bupleuri, barbary wolfberry fruits, polygonum multiflorum, radix angelica sinensis, radix paeoniae alba, cortex acanthopanacis, China roses, cistanche, codonopsis pilosula, rhodiola rosea, sanicula astrantifolia wolff ex kreschmer, sealwort, gorgon fruits, colla corii asini, three-leaf pear grass, Chinese holly leaves, cynomorium songaricum and semen sesami nigrum. The traditional Chinese medicine can more effectively promote absorption of iron of a human body, can be used for preventing and treating iron-deficiency anemia in daily life and is good in taste and free of stimulation to the stomach and intestine.
Description
Technical field
The present invention relates to health product technology field, particularly relate to a kind of medicine and health product of the double QI invigorating of enriching blood for prevention and therapy iron deficiency anemia.
Background technology
Iron deficiency anemia is a kind of trace element deficiency that sickness rate is the highest, is a kind of common food deficiency disease, and whole world Anemic patients is more than 2,000,000,000, and wherein 50% belongs to iron deficiency anemia, and the average prevalence of anemia of China resident reaches 20.1%.Among the crowd being generally considered to be " normal person ", about have the people of 11% to be in iron deficiency anemia state, especially in child and adolescent girls, this has become a clinical treatment problem highly paid attention to.
Anemia not only shows as the symptom such as palor, shortness of breath and palpitation, and also usually with the decline of muscle power, endurance and study, work capacity, lassitude and weak is one of the most common and symptom of occurring the earliest of anemia.
Iron deficiency anemia because storing iron deficiency in body, affect haemachrome synthesis and cause, be characterized in that bone marrow, liver, spleen lack stainability ferrum, cause the reason of iron deficiency to mainly contain: the requirement of ferrum increases and the malabsorption of Deficiency of Intake, ferrum or lose blood.In adult, chronic hemorrhage on a small quantity be also cause the modal reason of iron deficiency anemia.
In order to improve iron deficiency anemia, current western medicine mainly adopts iron supplementary, the object of iron in treatment iron deficiency anemia is adopted to have two, one is to provide the ferrum element required for synthetic hemoglobin, the pathophysiological change that torsion iron deficiency loss itself and anemia cause, improve the symptom of anemia, two is that supplementary body Chu Tie pond is (as bone marrow, spleen etc.) in storage iron, thus fundamentally improve the Iron status of body, body is made to be unlikely to again to affect hemoglobin synthesis when short-term or slight ferrum imbalance of supply and demand, cause anemia, adopt iron in treatment, clinical efficacy is rapid, but easily cause the untoward reaction of gastrointestinal tract etc., cause diarrhoea, the generation of the symptoms such as vomiting, because body exists larger individual variation to the absorption of ferrum and metabolism, time phase difference required for the therapeutic purposes reach different patient is very large, the course for the treatment of is not enough, anemia can not be improved or store ferrum and can not get supplying, Clinical observations, excessive accumulation in the body of ferrum can be caused, a series of harmful effect is produced to body.
In general, ferrous iron comparatively ferric iron be more conducive to absorption of human body.Commercially have various iron supplement food and preparation although existing, in fact, the iron supplement effect of these products is unsatisfactory.This may be because the approach of ferrum absorption is very incorrect on the one hand, such as oral ferrous sulfate tablet, although the ferrous sulfate amount taken is comparatively large, body does not have ability to absorb so large amount, so most of ferrum has been depleted again, small part has been only had to be absorbed by body and play physiological function; May be not fully utilized because iron fortified food product enters in human body on the other hand, bioavailability depends on the chemical form of element itself and the content in food, may due to dosage form or preservation improper, ferrous iron in quite a few iron preparation is oxidized to ferric iron before entering human body, loses the value that body utilizes; In addition, even if human body has taken in enough ferrum, if but be not fully absorbed and play a role, or cause the absorption of ferrum element to suppress due to the interaction between various nutrients, make it not be fully used, then still can not alleviate sideropenic present situation, therefore, also need to develop high iron fortified food product or the preparation sending more effective high bioavailability, in order to prevent and treat iron deficiency anemia.
The traditional Chinese medical science is thought, anemia belongs to the category of " syndrome of deficiency of blood ", by the principle of " weakened configuration person; warming with drugs of thick nature; insufficiency of essence person, tonifying with drugs of thick flavor ", and tonifying for deficiency syndrome, train it basic, invigorating the spleen and regulating the stomach, strengthens self resistance against diseases, and short its absorbs and hemopoietic function, deficiency syndrome should be treated by tonifying method, this disease is mainly caused by the reason such as eating and drinking without temperance, innate deficiency, obstinate disease, infection parasites.Blood stored in the liver, have storage blood, regulate blood volume, prevent hemorrhage function, liver master dredges rushes down, can mechanism of qi be regulated, help transporting and transforming function of the spleen and stomach, taste the foundation of acquired constitution, source of generating QI and blood, system blood dirty, liver and regulating qi, mechanism of qi fluent then taste hemopoietic liquid is normal, QI and blood and life, QI and blood row is in body, more bad in the catharsis effect of liver, blood stored in the liver and the spleen governs the blood complement each other, and jointly prevent outside blood oozing from the body openings or subcuta neous tissue arteries and veins, qi promoting blood production, therefore enrich blood and need take into account QI invigorating, QI and blood is with mending, and spleen invigorating helps fortune.In the side's of enriching blood medicine, compatibility QI invigorating medicine, the effect of qi-supplementing, blood-engendering can be received, Chinese medicine preparation is better than Oral Iron Preparations improving in symptom, and effect is improved to gastrointestinal function, not easily recur after drug withdrawal, this points out us to utilize tcm syndrome differentiation and treatment, play the characteristic of the traditional Chinese medical science to improve clinical efficacy, and the advantage of traditional Chinese medical science preventive treatment of disease can be played.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of health product for preventing and treating iron deficiency anemia, and it more effectively can promote that body is to the absorption of ferrum, can be used for preventing and treating iron deficiency anemia in daily life, and mouthfeel is good, non-stimulated to gastrointestinal.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition of double QI invigorating of enriching blood, its crude drug comprises Radix Panacis Quinquefolii, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Radix Rehmanniae Preparata, Arillus Longan, Radix Bupleuri, Fructus Lycii, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Acanthopancis, Flos Rosae Chinensis, Herba Cistanches, Radix Codonopsis, Radix Rhodiolae, Radix Saniculae Astrantifoliae, Rhizoma Polygonati, Semen Euryales, Colla Corii Asini, Herba Lysimachiae Insignis, Folium Mahoniae, Herba Cynomorii and Semen Sesami Nigrum.
Wherein, in described Chinese medicine composition, the weight of each raw material is respectively Radix Panacis Quinquefolii 45 weight portion ~ 55 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion ~ 40 weight portion, Fructus Jujubae 60 weight portion ~ 70 weight portion, Radix Rehmanniae Preparata 80 weight portion ~ 90 weight portion, Arillus Longan 35 weight portion ~ 45 weight portion, Radix Bupleuri 30 weight portion ~ 40 weight portion, Fructus Lycii 50 weight portion ~ 60 weight portion, Radix Polygoni Multiflori 80 weight portion ~ 90 weight portion, Radix Angelicae Sinensis 60 weight portion ~ 70 weight portion, the Radix Paeoniae Alba 50 weight portion ~ 60 weight portion, Cortex Acanthopancis 35 weight portion ~ 45 weight portion, Flos Rosae Chinensis 20 weight portion ~ 30 weight portion, Herba Cistanches 55 weight portion ~ 65 weight portion, Radix Codonopsis 15 weight portion ~ 25 weight portion, Radix Rhodiolae 20 weight portion ~ 30 weight portion, Radix Saniculae Astrantifoliae 30 weight portion ~ 40 weight portion, Rhizoma Polygonati 55 weight portion ~ 65 weight portion, Semen Euryales 45 weight portion ~ 55 weight portion, Colla Corii Asini 110 weight portion ~ 120 weight portion, Herba Lysimachiae Insignis 35 weight portion ~ 45 weight portion, Folium Mahoniae 20 weight portion ~ 30 weight portion, Herba Cynomorii 20 weight portion ~ 30 weight portion and Semen Sesami Nigrum 50 weight portion ~ 60 weight portion.
Wherein, in described Chinese medicine composition, the weight portion of each raw material is Radix Panacis Quinquefolii 50 weight portion, the Rhizoma Atractylodis Macrocephalae 35 weight portion, Fructus Jujubae 65 weight portion, Radix Rehmanniae Preparata 85 weight portion, Arillus Longan 40 weight portion, Radix Bupleuri 35 weight portion, Fructus Lycii 55 weight portion, Radix Polygoni Multiflori 85 weight portion, Radix Angelicae Sinensis 65 weight portion, the Radix Paeoniae Alba 55 weight portion, Cortex Acanthopancis 40 weight portion, Flos Rosae Chinensis 25 weight portion, Herba Cistanches 60 weight portion, Radix Codonopsis 20 weight portion, Radix Rhodiolae 25 weight portion, Radix Saniculae Astrantifoliae 35 weight portion, Rhizoma Polygonati 60 weight portion, Semen Euryales 50 weight portion, Colla Corii Asini 115 weight portion, Herba Lysimachiae Insignis 40 weight portion, Folium Mahoniae 25 weight portion, Herba Cynomorii 25 weight portion and Semen Sesami Nigrum 55 weight portion.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, be specially:
The first step, the extraction of above-mentioned traditional Chinese medicinal composition raw materials;
Second step, the purification of extract.
Wherein, the described first step is specially raw material medicaments in part by weight mixing each in described Chinese medicine, stir, add the water relative to mixture quality 6 ~ 8 times, the pH value of water is regulated to be 2 ~ 3 with the hydrochloric acid that volumetric concentration is 5%, soak 1 hour ~ 2 hours, decoct 3 hours ~ 5 hours subsequently, decoction liquor is filtered, filtering residue adds the water relative to mixture quality 4 ~ 6 times again, decoct 3 hours ~ 5 hours, decoction liquor is filtered, decoction liquor is merged, be 10% sodium hydroxide adjust ph to 6 ~ 7 by mass percentage concentration, obtain extracting solution, at extracting solution simmer down to 50 DEG C, relative density is the mastic of 1.10 ~ 1.20, be cooled to room temperature, add concentration be 95% ethanol reach 60% to alcohol content, 0 DEG C of cold preservation 12 hours, filter, filtrate reduced in volume reclaims ethanol, being concentrated into relative density at 50 DEG C is the mastic of 1.10 ~ 1.20.
Wherein, the thick paste that described second step is specially the first step obtains adds on the macroporous adsorptive resins of D101 type, the water of 1 ~ 2 times of column volume is first adopted to rinse, be the ethanol elution of 30% at employing 3 ~ 5 times of column volume determining alcohols, 3 ~ 5 times of column volume determining alcohols are adopted to be the ethanol elution of 70% again, collect determining alcohol be 30% ethanol elution and determining alcohol be the ethanol elution of 70%, at being evaporated to 50 DEG C, relative density is 1.10 ~ 1.20, add isopyknic water, 0 DEG C of cold preservation 12 hours, filter, filtrate is concentrated except desolventizing, pulverize, dry, obtain Chinese medicine composition extraction purification thing.
Present invention also offers a kind of blood-enriching oral liquid, it comprises above-mentioned Chinese medicine composition, vitamin C, vitamin B
2, brown sugar, the water of iron supplementary and surplus.
Wherein, in described blood-enriching oral liquid, the percentage by weight of each component is respectively described Chinese medicine composition 30% ~ 40%, vitamin C 3% ~ 5%, vitamin B
23% ~ 5%, brown sugar 10% ~ 18%, the water of iron supplementary 8% ~ 12% and surplus.
Wherein, in described blood-enriching oral liquid health product, the percentage by weight of each component is described Chinese medicine composition 35%, vitamin C 4%, vitamin B
24%, brown sugar 15%, the water of iron supplementary 10% and surplus.
Present invention also offers the preparation method of this blood-enriching oral liquid, be specially:
The first step, prepares Chinese medicine composition according to the method described above;
Second step, is dissolved in 25g sodium hydroxide in distilled water and is prepared into the soda bath that mass percentage concentration is 10%, slowly add 50g ferrous porphyrin subsequently, be stirred to and dissolve completely, obtains solution;
Second step, by 75g brown sugar, 20g vitamin C, 20g vitamin B
2slowly add in the solution of second step acquisition with Chinese medicine composition prepared by the 175g first step, stir completely, solution ph regulated value 6 ~ 8,0 DEG C of cold preservation 12 hours, filter, with distilled water diluting to 500ml, 60 ~ 80 DEG C of hot embeddings, 121 DEG C of autoclavings, lamp inspection, inspection, packaging.
Beneficial effect of the present invention:
Chinese medicine composition provided by the invention and blood-enriching oral liquid health product more effectively can promote that body is to the absorption of ferrum, can be used for preventing and treating iron deficiency anemia in daily life, and mouthfeel is good, non-stimulated to gastrointestinal.
Detailed description of the invention
The traditional Chinese medical science is thought, anemia belongs to the category of " syndrome of deficiency of blood ".Deficiency syndrome should be treated by tonifying method, this disease is mainly caused by the reason such as eating and drinking without temperance, innate deficiency, obstinate disease, infection parasites.
The root of kidney asthenia as the principal aspect disease, kidney storing essence, the raw marrow of main bone, essence can change blood, marrow energy hemopoietic, essence and blood sharing the same origin, and then essence and blood source of suffering from a deficiency of the kidney is not enough, and temper depends on the warm of the yang-energy of kidney can normal metaplastic be precise and tiny is changed to blood, and marrow virtual loss of suffering from a deficiency of the kidney then blood must be empty few.Kidney is that whole body vigour is basic, kidney storing essence, raw marrow, main bone, therefore kidney essense is abundant, then can change and be blood.Modern study thinks that traditional Chinese medical science invigorating kidney, promoting blood circulation can conditioner body immunity function, stimulates hemopoietic function of bone marrow, improves bone marrow microenvironment, make hemoglobin reduction no matter the cause of disease removal or regenerating recovery all plays an important role.Modern medicine thinks the organ for storage ferrum such as bone marrow, liver, spleen, and ferrum is the main component of synthetic hemoglobin, thinks kidney controlling essence storage with the traditional Chinese medical science, and the raw marrow of main bone, marrow hemopoietic has points of resemblance.
Taste are the key of primary disease, and spleen and kidney are " day after tomorrow " and the relation of " congenital ", are mutual promotions, mutually promote, pathology also influences each other, reciprocal causation.Insufficiency of kidney-YANG can not warm spleen sun; Deficiency of spleen-YANG is weak, and inability of food and drink to be digested and transported is precise and tiny, and kidney yang is lost it and supplemented nutrition." qi being the governor of blood, blood being the material foundation of QI ", gas and blood have therebetween and contact closely.Qi promoting blood production, in the composition referring to blood and generative process thereof, all be unable to do without gentle motion change one gasification function of gas.Ying-qi and body fluid are the key components of blood, and they are from the essence of water and grain of taste institute transporting.Change into essence of water and grain from the ingesta taken in, then change into ying-qi and body fluid, then change into blood, all be unable to do without the motion change of gas.Spleen invigorating can supplement the deficiency of taste, and for QI and blood biochemistry provides home, QI invigorating can be invigorated blood circulation hemopoietic.The generation of blood and the relation of spleen the closest." blood person essence of water and grain is born in spleen ", " spleen is source of generating QI and blood ".Taste are received digesting food, produce cereal nutrient, and for the generation of blood provides Material Source, the raw function of change of spleen is the power that blood generates.Temper also has the function of having blood under one's command and normally running.The many reasons such as eating and drinking without temperance, overstrain, weakness due to chronic disease all can undermine spleen and stomach function, cause water paddy and are received deficiency, cause the weary source of cereal nutrient, or occur the raw miopragia of spleenization, precise and tiny Use barriers, thus cause primary disease to occur.Deficiency-weakness of spleen-QI, has dereliction of duty under one's command, and outside blood oozing from the body openings or subcuta neous tissue arteries and veins, Massive Bleeding (acute or chronic) also can cause primary disease.
" qi being the governor of blood, blood being the material foundation of QI ", gas and blood have therebetween and contact closely.Qi promoting blood production, in the composition referring to blood and generative process thereof, all be unable to do without gentle motion change one gasification function of gas.Ying-qi and body fluid are the key components of blood, and they are from the essence of water and grain of taste institute transporting.Change into essence of water and grain from the ingesta taken in, then change into ying-qi and body fluid, then change into blood, all be unable to do without the motion change of gas.Therefore say, qi promoting blood production.Gas is prosperous, then the function changing hemopoietic liquid is also strong; The deficiency of vital energy, then the function changing hemopoietic liquid is also weak, very then can cause blood deficiency.
Blood stored in the liver, have storage blood, regulate blood volume, prevent hemorrhage function, liver master dredges rushes down, can mechanism of qi be regulated, help transporting and transforming function of the spleen and stomach, taste the foundation of acquired constitution, source of generating QI and blood, system blood dirty, liver and regulating qi, mechanism of qi fluent then taste hemopoietic liquid is normal, QI and blood and life, QI and blood row is in body, more bad in the catharsis effect of liver, blood stored in the liver and the spleen governs the blood complement each other, and jointly prevent outside blood oozing from the body openings or subcuta neous tissue arteries and veins, qi promoting blood production, therefore enrich blood and need take into account QI invigorating, QI and blood is with mending, and spleen invigorating helps fortune.In the side's of enriching blood medicine, compatibility QI invigorating medicine, can receive the effect of qi-supplementing, blood-engendering.
Theoretical based on above-mentioned Chinese traditional treatment, the present invention proposes with invigorating the spleen and benefiting QI, promoting blood flow to regulate menstruation, soothing the liverly enrich blood as principle, there is provided a kind of Chinese medicine composition of the double QI invigorating of enriching blood for prevention and therapy iron deficiency anemia, its crude drug comprises Radix Panacis Quinquefolii, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Radix Rehmanniae Preparata, Arillus Longan, Radix Bupleuri, Fructus Lycii, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Acanthopancis, Flos Rosae Chinensis, Herba Cistanches, Radix Codonopsis, Radix Rhodiolae, Radix Saniculae Astrantifoliae, Rhizoma Polygonati, Semen Euryales, Colla Corii Asini, Herba Lysimachiae Insignis, Folium Mahoniae, Herba Cynomorii and Semen Sesami Nigrum.
Fang Zhong, Radix Panacis Quinquefolii is containing the total soap two of Radix Ginseng, the total soap two of Radix Ginseng in vivo and in vitro all can the propagation of hemopoietic stem cell and hemopoietic progenitor cell, there is effect of similar hemopoietic growth factor, the Rhizoma Atractylodis Macrocephalae can increase the secretion of digestive system, hemopoietic system, raise erythrocyte and hemoglobin, improve lymhocyte transformation rate, Arillus Longan the kidney invigorating and essence nourishing, benefiting QI and nourishing blood, Radix Rehmanniae Preparata can hemopoietic system, raise erythrocyte, Fructus Jujubae contains vitamin C, ferrum etc., gastric enzyme can be increased, promote the absorption of ferrum, Radix Polygoni Multiflori can hemopoietic cytokine secretion, the synthesis of erythrocytic growth promoter and hemoglobin can be promoted, gas reason of waking up spleen, Radix Bupleuri depressed liver-energy dispersing and QI regulating, Fructus Lycii nourishing the liver and kidney, control blood deficiency and yellow complexion, with Radix Polygoni Multiflori, Radix Angelicae Sinensis compatibility can subsidize essence and blood, YIN nourishing is with pig sample, Fructus Lycii can also immune stimulatory hemopoietic system, Radix Angelicae Sinensis is pungent sweet and warm, enrich blood and seek, contained vitamin B
12and folic acid can anti-anemia action, that ferrum absorbs indispensable material, Radix Paeoniae Alba nourishing blood for regulating menstruation, for blood deficiency and yellow complexion, expelling wind and removing dampness, liver and kidney tonifying, Flos Rosae Chinensis promoting blood flow to regulate menstruation, dispersing the stagnated live-QI to relieve the stagnation of QI, Herba Cistanches kidney-replenishing, benefiting essence-blood, the pain relieving of Radix Codonopsis promoting blood circulation to restore menstrual flow, Radix Rhodiolae benefiting QI for activating blood circulation, promote blood circulation and relieving asthma, Rhizoma Polygonati promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, Semen Euryales supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, Colla Corii Asini nourishing blood YIN nourishing, moisturize hemostasis, Herba Lysimachiae Insignis dispelling wind and removing obstruction in the collateral, promoting flow of QI and blood, Radix Saniculae Astrantifoliae tonifying the lung and stopping cough, kidney tonifying nourishes heart, Folium Mahoniae liver and kidney tonifying, wind-damp dispelling, Herba Cynomorii kidney invigorating and YANG supporting, benefiting essence-blood, Semen Sesami Nigrum invigorating the liver and kidney, support essence and blood, all medicines share, spleen invigorating helps fortune, mediation gastrointestinal, qi-supplementing, blood-engendering, and mild in medicine property and, mouthfeel is suitable for.
Further, described Chinese medicine composition only has above-mentioned raw materials medicine to form.
In described Chinese medicine composition, the weight of each raw material is respectively Radix Panacis Quinquefolii 45 weight portion ~ 55 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion ~ 40 weight portion, Fructus Jujubae 60 weight portion ~ 70 weight portion, Radix Rehmanniae Preparata 80 weight portion ~ 90 weight portion, Arillus Longan 35 weight portion ~ 45 weight portion, Radix Bupleuri 30 weight portion ~ 40 weight portion, Fructus Lycii 50 weight portion ~ 60 weight portion, Radix Polygoni Multiflori 80 weight portion ~ 90 weight portion, Radix Angelicae Sinensis 60 weight portion ~ 70 weight portion, the Radix Paeoniae Alba 50 weight portion ~ 60 weight portion, Cortex Acanthopancis 35 weight portion ~ 45 weight portion, Flos Rosae Chinensis 20 weight portion ~ 30 weight portion, Herba Cistanches 55 weight portion ~ 65 weight portion, Radix Codonopsis 15 weight portion ~ 25 weight portion, Radix Rhodiolae 20 weight portion ~ 30 weight portion, Radix Saniculae Astrantifoliae 30 weight portion ~ 40 weight portion, Rhizoma Polygonati 55 weight portion ~ 65 weight portion, Semen Euryales 45 weight portion ~ 55 weight portion, Colla Corii Asini 110 weight portion ~ 120 weight portion, Herba Lysimachiae Insignis 35 weight portion ~ 45 weight portion, Folium Mahoniae 20 weight portion ~ 30 weight portion, Herba Cynomorii 20 weight portion ~ 30 weight portion and Semen Sesami Nigrum 50 weight portion ~ 60 weight portion.
Further, the weight portion of each raw material more preferably Radix Panacis Quinquefolii 50 weight portion ~ 55 weight portion in described Chinese medicine composition, the Rhizoma Atractylodis Macrocephalae 35 weight portion ~ 40 weight portion, Fructus Jujubae 65 weight portion ~ 70 weight portion, Radix Rehmanniae Preparata 85 weight portion ~ 90 weight portion, Arillus Longan 40 weight portion ~ 45 weight portion, Radix Bupleuri 30 weight portion ~ 35 weight portion, Fructus Lycii 55 weight portion ~ 60 weight portion, Radix Polygoni Multiflori 85 weight portion ~ 90 weight portion, Radix Angelicae Sinensis 65 weight portion ~ 70 weight portion, the Radix Paeoniae Alba 55 weight portion ~ 60 weight portion, Cortex Acanthopancis 35 weight portion ~ 40 weight portion, Flos Rosae Chinensis 20 weight portion ~ 25 weight portion, Herba Cistanches 60 weight portion ~ 65 weight portion, Radix Codonopsis 15 weight portion ~ 20 weight portion, Radix Rhodiolae 20 weight portion ~ 25 weight portion, Radix Saniculae Astrantifoliae 30 weight portion ~ 35 weight portion, Rhizoma Polygonati 55 weight portion ~ 60 weight portion, Semen Euryales 45 weight portion ~ 50 weight portion, Colla Corii Asini 115 weight portion ~ 120 weight portion, Herba Lysimachiae Insignis 35 weight portion ~ 40 weight portion, Folium Mahoniae 20 weight portion ~ 25 weight portion, Herba Cynomorii 20 weight portion ~ 25 weight portion and Semen Sesami Nigrum 55 weight portion ~ 60 weight portion.
Further, the weight portion of each raw material more preferably Radix Panacis Quinquefolii 50 weight portion in described Chinese medicine composition, the Rhizoma Atractylodis Macrocephalae 35 weight portion, Fructus Jujubae 65 weight portion, Radix Rehmanniae Preparata 85 weight portion, Arillus Longan 40 weight portion, Radix Bupleuri 35 weight portion, Fructus Lycii 55 weight portion, Radix Polygoni Multiflori 85 weight portion, Radix Angelicae Sinensis 65 weight portion, the Radix Paeoniae Alba 55 weight portion, Cortex Acanthopancis 40 weight portion, Flos Rosae Chinensis 25 weight portion, Herba Cistanches 60 weight portion, Radix Codonopsis 20 weight portion, Radix Rhodiolae 25 weight portion, Radix Saniculae Astrantifoliae 35 weight portion, Rhizoma Polygonati 60 weight portion, Semen Euryales 50 weight portion, Colla Corii Asini 115 weight portion, Herba Lysimachiae Insignis 40 weight portion, Folium Mahoniae 25 weight portion, Herba Cynomorii 25 weight portion and Semen Sesami Nigrum 55 weight portion.
In described Chinese medicine composition, each raw material pharmacology is as follows:
Radix Panacis Quinquefolii: sweet in the mouth, micro-hardship, cool in nature, GUIXIN, lung, kidney channel, have boosting qi and nourishing yin, effect of clearing away heat and promoting production of body fluid, and cure mainly deficiency of vital energy the moon and lose, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, dryness of the mouth and throat.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature, enter spleen, stomach warp, have spleen reinforcing promoting the circulation of QI, dampness diuretic, strengthening superficial resistance to stop perspiration, the effect that activating the spleen is moisturized, be mainly used in the feeling of fullness diarrhoea that dysfunction of the spleen in transportation, QI failing to transform into body fluid are caused, phlegm retention edema; The vexed lazyness speech of deficiency of QI in middle-JIAO, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, sweating due to debility spontaneous perspiration.
Fructus Jujubae: sweet in the mouth, warm in nature, enter spleen, stomach warp, there is the effect of air making-up and spleen enlivening, nourishing blood to tranquillize the mind, harmonizing yingfen and weifen, the mitigation property of medicine, for weakness of the spleen and stomach, fatigue and asthenia, anorexia and loose stool, the cards such as insufficiency of vital energy and blood, has a headache and fever, sweating hot blast.
Radix Rehmanniae Preparata: have another name called Radix Rehmanniae Preparata, sweet in the mouth, slightly warm in nature, enters liver, kidney channel, has YIN nourishing of enriching blood, and beneficial essence fills out the effect of marrow, for blood deficiency and yellow complexion; Dizzy, cardiopalmus, insomnia, menoxenia, collapses more than; Hepatic and renal YIN deficiency, night sweat, sufficient knee joint pain, soreness of the waist and knees, Hiccough and deaf, the head is dim-sighted; Seminal emission sexual impotence; Infertility; Menoxenia; Metrostaxis; Early whitening of beard and hair; Quench one's thirst; Constipation; To suffer from a deficiency of the kidney the cards such as dyspnea with rapid and short breath.
Arillus Longan: warm in nature, taste is sweet, has invigorating the heart and spleen, effect of nourishing blood to tranquillize the mind, for cards such as insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Radix Bupleuri: bitter in the mouth, cold nature, returns liver, gallbladder meridian, has evacuation and brings down a fever, and effect of yang invigorating soothing liver-QI cures mainly cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the cards such as uterus comes off, menoxenia.
Fructus Lycii: sweet in the mouth, property are flat, enter liver, kidney channel, have liver and kidney tonifying, nourish blood enrich blood, the effect of replenishing vital essence to improve eyesight, nourishing the lung to arrest cough, be mainly used in Liver and kidney two void, the soreness of the waist and knees of asthenia of essence and blood, dizziness and tinnitus, seminal emission tinnitus, unconsciously sweat and tire; The sexual impotence of insufficiency of kidney-YANG, sterile; The cards such as the dim-sighted and deficiency of YIN chronic cough of the eyes of deficiency of YIN-essence, deficiency of liver-blood, Fructus Lycii can promote liver cell regeneration, the effect of enhancing non-specific immunity function.
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature, returns liver, kidney channel, has effect of nourishing the blood and yin, loosening bowel to relieve constipation, cures mainly blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; The cards such as hemorrhoid, Radix Polygoni Multiflori can make telangiectasis.
Radix Angelicae Sinensis: latin name AngelicaeSinensisRadix, sweet in the mouth, pungent, warm in nature, enter liver, the heart, spleen channel, having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation, cures mainly having a dizzy spell of deficiency of heart-blood, fatigue and weakness, shortness of breath and palpitation, the sea of blood is hollow, the menoxenia of the cold and deficiency of CHONG and REN meridians or congestion retardance, dysmenorrhoea, produces or stomachache, and other blood stasis are had a pain and the card such as the constipation of deficiency of YIN insufficiency of blood dryness of the intestine, its can improve uterus blood circulation, alleviate pelvic congestion, relieving dysmenorrhea.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature, enters liver, spleen channel, joint venture of nourishing blood, easing the affected liver to relieve pain, and the effect of suppressing liver-YANG is mainly used in deficiecny of liver-YIN, the headache feeling of fullness in the head of excessive rising of liver-YANG, vertigo and tinnitus, irritable; Deficiency of liver-blood, battalion defends the menoxenia of inanition, metrorrhagia and metrostaxis; The dysmenorrhea of deficiency of the liver stasis dampness; Disharmony of nutrient QI with defensive QI, the cloudy outer inducing vomiting spontaneous sweating of battalion; The gastral cavity abdomen pain over the hypochondriac region of depression of liver-QI, dysentery is suffered from abdominal pain; Deficiency and exhaustion of liver-YIN, passages through which vital energy circulates loses the cards such as the carpopedal spasm pain of supporting, there are antithrombus formation and hepatoprotective effect, inhibitory action is had to dysentery bacterium, Bacillus typhi, blood dissolubility streptococcus, Diplococcus pneumoniae, bacillus pyocyaneus, staphylococcus aureus, the Radix Paeoniae Alba and Radix Rehmanniae Preparata share, enrich blood with nourishing YIN and benefiting blood, treat blood deficiency dizziness and wait card.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature, return liver, kidney channel, have wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the effect of arteries and veins of invigorating blood circulation, for anemofrigid-damp arthralgia; Lumbocrural pain; Muscles and bones flaccidity is soft; Children's's walking retardation in children; Body void is frail; Traumatic injury; Fracture; Edema; Foot gas; Uncontrolled urination such as to be itched at the card.
Flos Rosae Chinensis: latin name RosaeChinensisFlos, sweet in the mouth, warm in nature, return Liver Channel, have promoting blood flow to regulate menstruation, effect of dispersing the stagnated live-QI to relieve the stagnation of QI, cures mainly qi depression to blood stasis, menoxenia, dysmenorrhea, amenorrhea, the cards such as distending pain in the chest and hypochondrium.
Herba Cistanches: sweet in the mouth, one-tenth, warm in nature, enter kidney, large intestine channel, have kidney-replenishing, benefiting essence-blood, the effect of loosening bowel to relieve constipation, for kidney yang deficiency, the impotence and premature ejaculation of asthenia of essence and blood, sterility and infertility, soreness of waist and knee joint, Hiccough and deaf, frequent micturition urine number, suffer from a deficiency of the kidney dryness of the intestine and puerperal blood deficiency, deficiency of body fluid after being ill the card such as constipation.
Radix Codonopsis is traditional tonic that China commonly uses, and the Radix Codonopsis that ancient times produce with area, Shangdang, Shanxi is top grade, has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function.In addition castering action is had to the leukopenia that chemotherapy radiotherapy causes.Radix Codonopsis has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst." Bencao Congxin " is recorded: " invigorating the spleen and replenishing QI and taste, relieving thirst and restlessness.Middle feeble QI is weak, mends in order to adjust, very smooth and proper.”
Radix Rhodiolae: sweet is bitter, flat.Return lung, heart channel, have benefiting QI for activating blood circulation, effect of relievining asthma of promoting blood circulation, for blood stasis due to qi deficiency, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, the cards such as asthenia asthma, Radix Rhodiolae can improve the content of protein in Carnis Gallus domesticus.
Radix Saniculae Astrantifoliae: sweet in the mouth, micro-hardship, property is put down, and has tonifying the lung and stopping cough, effect that kidney tonifying nourishes heart, cures mainly phthisical cough, void is coughed, lumbago due to renal deficiency, dizzy, the cards such as cardiopalmus.
Rhizoma Polygonati: can calm the nerves, wind pain is swollen in the wide intestinal of lively atmosphere blood, sending down the abnormal ascending QI, heat clearing away, long-pendingization of dispelling is stagnant, bowel relieving, intestine moistening, spleen invigorating lung moistening, cough-relieving, relieving asthma, antiinflammatory, antiallergic, heart tonifying, spleen invigorating lung moistening, the effect such as beauty treatment., be not medicine, be not health product to Rhizoma Polygonati--seven major nutrient complete set, is to work as the food that meal eats, and but has remarkable healthy nutritive value and outstanding dietetic therapy effect.Rhizoma Polygonati is rich in oils and fats, the many sliding profits of property.Modern pharmacological research shows, these compositions have the merit of spleen invigorating lung moistening.
Semen Euryales: sweet in the mouth, puckery, property is put down.Return spleen, kidney channel.Have supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, the function of damp eliminating leukorrhagia stopping, cures mainly emission, diarrhea due to hypofunction of the spleen, and insufficiency of the spleen nebulousurine is with inferior card.
Colla Corii Asini: sweet in the mouth, property are flat, and enter lung, liver, kidney channel, have tonifying blood and arresting bleeding, nourshing Yin and drynsessmoistening prescription effect, can be used for various asthenia symptom, especially the shallow complexion of blood deficiency, thin and weak weak, the head is dizzy, palpitation and insomnia; Malnutritional anemia, thrombocytopenic purpura; Deficient property hemoptysis; Haematemesis hematuria is had blood in stool; The cough dry pharynx of lung-dryness syndrome due to deficiency of YIN, sputum mixed with blood; The symptom such as spasm of muscles and vessels, tetany of pathogenic heat lingering, deficiency of YIN blood consumption, stirring-up of pathogenic wind in the interior resulting from deficiency, Colla Corii Asini has the erythrocytic generation of promotion, increases blood calcium concentration, promotes the effect of hemostasis, and contributes to the immunologic function strengthening human body.
Herba Lysimachiae Insignis: acrid in the mouth, hardship, warm in nature, GUIXIN, lung meridian, have dispelling wind and removing obstruction in the collateral, and effect of promoting flow of QI and blood, cures mainly rheumatic arthralgia, epigastric pain, treating swelling and pain by traumatic injury, the cards such as cough due to consumptive disease.
Folium Mahoniae: bitter in the mouth, cool in nature, return liver, kidney channel, have clearind deficient heat, liver and kidney tonifying, effect of wind-damp dispelling, cures mainly hectic fever due to deficiency of YIN, and cough hemoptysis, has a dizzy spell, soreness of the waist and knees, the cards such as rheumatic arthralgia.
Herba Cynomorii: sweet in the mouth, warm in nature, return spleen, kidney, large intestine channel, there is kidney-replenishing, benefiting essence-blood, effect of loosening bowel to relieve constipation, cure mainly insufficiency of kidney-YANG, essence and blood void is lost, sexual impotence, infertile, soreness of the waist and knees; The cards such as dryness of the intestine constipation.
Semen Sesami Nigrum: sweet in the mouth, property is put down, and enters liver, kidney, large intestine channel, has invigorating the liver and kidney, benefiting essence-blood, the effect that intestine moistening is dry, for dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, the cards such as dryness of the intestine constipation.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, be specially:
The first step, the extraction of above-mentioned Chinese medicine composition;
Second step, the purification of extract.
The described first step is specially raw material medicaments in part by weight mixing each in described Chinese medicine, stir, add the water relative to mixture quality 6 ~ 8 times, the pH value of water is regulated to be 2 ~ 3 with the hydrochloric acid that volumetric concentration is 5%, soak 1 hour ~ 2 hours, decoct 3 hours ~ 5 hours subsequently, decoction liquor is filtered, filtering residue adds the water relative to mixture quality 4 ~ 6 times again, decoct 3 hours ~ 5 hours, decoction liquor is filtered, decoction liquor is merged, be 10% sodium hydroxide adjust ph to 6 ~ 7 by mass percentage concentration, obtain extracting solution, at extracting solution simmer down to 50 DEG C, relative density is the mastic of 1.10 ~ 1.20, be cooled to room temperature, add concentration be 95% ethanol reach 60% to alcohol content, 0 DEG C of cold preservation 12 hours, filter, filtrate reduced in volume reclaims ethanol, being concentrated into relative density at 50 DEG C is the mastic of 1.10 ~ 1.20.
The thick paste that described second step is specially the first step obtains adds on the macroporous adsorptive resins of D101 type, the water of 1 ~ 2 times of column volume is first adopted to rinse, be the ethanol elution of 30% at employing 3 ~ 5 times of column volume determining alcohols, 3 ~ 5 times of column volume determining alcohols are adopted to be the ethanol elution of 70% again, collect determining alcohol be 30% ethanol elution and determining alcohol be the ethanol elution of 70%, at being evaporated to 50 DEG C, relative density is 1.10 ~ 1.20, add isopyknic water, 0 DEG C of cold preservation 12 hours, filter, filtrate is concentrated except desolventizing, pulverize, dry, obtain Chinese medicine composition extraction purification thing.
The invention provides a kind of blood-enriching oral liquid, it comprises the Chinese medicine composition promoting that iron supplementary absorbs and enriches blood, vitamin C, vitamin B
2, brown sugar, the water of iron supplementary and surplus, in described blood-enriching oral liquid, the percentage by weight of each component is respectively described Chinese medicine composition 30% ~ 40%, vitamin C 3% ~ 5%, vitamin B
23% ~ 5%, brown sugar 10% ~ 18%, the water of iron supplementary 8% ~ 12% and surplus.
Wherein, in described blood-enriching oral liquid health product, the percentage by weight of each component is described Chinese medicine composition 35%, vitamin C 4%, vitamin B
24%, brown sugar 15%, the water of iron supplementary 10% and surplus.
Further, described blood-enriching oral liquid health product are only made up of said components.
Further, the mass percent sum of the above-mentioned each component of described blood-enriching oral liquid health product is 100%.
Vitamin C: also known as ascorbic acid, the ferric iron back that it can make human body be difficult to absorb becomes ferrous iron, promotes that intestinal is to the absorption of ferrum, improves liver to the utilization rate of ferrum, contribute to treating iron deficiency anemia.Vitamin C can also help ferrum to transfer to ferritin from carrier transferrins.It strengthens the function of some iron enzyme activity in addition in addition.
Vitamin B
2: also claiming riboflavin, is the important composition composition of many enzyme systems in body, the B if body is deficient in vitamin
2, there will be matter and energy metabolism disorder.Vitamin B
2also be form erythrocytic important substance.Research proves, it is absorbed with important effect to promotion ferrum.Have been reported title to be deficient in vitamin B
2anemia of pregnant woman easily there is iron deficiency anemia.Therefore appropriate vitamin B
2picked-up to prevention status of iron deficiency in pregnant women be highly profitable.
Brown sugar: sweet, gentle, nontoxic, enters liver, spleen.Can be used for moistening cardiopulmonary, and in help spleen, slow irritability, enriches blood, removing blood stasis with potent drugs.
Described iron supplementary is one or more mixing in sodium iron ethylenediaminetetraacetate, iron dextran, ferrous fumarate, ferrous lactate, ferric citrate or ferrous porphyrin, be preferably ferrous porphyrin, utilize biological extraction separation means to extract from animal blood to ferrous porphyrin be a kind of biological activity heme iron, relative to inorganic iron or Organic Iron, ferrous porphyrin can directly be absorbed fast by intestinal epithelial cell and be combined with hemoglobin, participates in the process of hemoglobin transport oxygen.
Present invention also offers the preparation method of this blood-enriching oral liquid, be specially:
The first step, prepares Chinese medicine composition according to the method described above;
Second step, is dissolved in 25g sodium hydroxide in distilled water and is prepared into the soda bath that mass percentage concentration is 10%, slowly add 50g ferrous porphyrin subsequently, be stirred to and dissolve completely, obtains solution;
Second step, by 75g brown sugar, 20g vitamin C, 20g vitamin B
2slowly add in the solution of second step acquisition with Chinese medicine composition prepared by the 175g first step, stir completely, solution ph regulated value 6 ~ 8,0 DEG C of cold preservation 12 hours, filter, with distilled water diluting to 500ml, 60 ~ 80 DEG C of hot embeddings, 121 DEG C of autoclavings, lamp inspection, inspection, packaging.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition 1
By Radix Panacis Quinquefolii 50g, Rhizoma Atractylodis Macrocephalae 35g, Fructus Jujubae 65g, Radix Rehmanniae Preparata 85g, Arillus Longan 40g, Radix Bupleuri 35g, Fructus Lycii 55g, Radix Polygoni Multiflori 85g, Radix Angelicae Sinensis 65g, Radix Paeoniae Alba 55g, Cortex Acanthopancis 40g, Flos Rosae Chinensis 25g, Herba Cistanches 60g, Radix Codonopsis 20g, Radix Rhodiolae 25g, Radix Saniculae Astrantifoliae 35g, Rhizoma Polygonati 60g, Semen Euryales 50g, Colla Corii Asini 115g, Herba Lysimachiae Insignis 40g, Folium Mahoniae 25g, Herba Cynomorii 25g and Semen Sesami Nigrum 55g mixes, stir, add the water of 8kg, the pH value of water is regulated to be 3 with the hydrochloric acid that volumetric concentration is 5%, soak 1 hour ~ 2 hours, decoct 5 hours subsequently, decoction liquor is filtered, filtering residue adds the water of 6kg again, decoct 5 hours, decoction liquor is filtered, decoction liquor is merged, be 10% sodium hydroxide adjust ph to 7 by mass percentage concentration, obtain extracting solution, at extracting solution simmer down to 50 DEG C, relative density is the mastic of 1.20, be cooled to room temperature, add concentration be 95% ethanol reach 60% to alcohol content, 0 DEG C of cold preservation 12 hours, filter, filtrate reduced in volume reclaims ethanol, being concentrated into relative density at 50 DEG C is the mastic of 1.20, the thick paste of acquisition is added on the macroporous adsorptive resins of D101 type, the water of 2 times of column volumes is first adopted to rinse, be the ethanol elution of 30% at employing 5 times of column volume determining alcohols, 5 times of column volume determining alcohols are adopted to be the ethanol elution of 70% again, collect determining alcohol be 30% ethanol elution and determining alcohol be the ethanol elution of 70%, at being evaporated to 50 DEG C, relative density is 1.20, add isopyknic water, 0 DEG C of cold preservation 12 hours, filter, filtrate is concentrated except desolventizing, pulverize, dry, obtain Chinese medicine composition 1.
Embodiment 2 Chinese medicine composition 2
By Radix Panacis Quinquefolii 55g, Rhizoma Atractylodis Macrocephalae 40g, Fructus Jujubae 70g, Radix Rehmanniae Preparata 90g, Arillus Longan 45g, Radix Bupleuri 35g, Fructus Lycii 60g, Radix Polygoni Multiflori 90g, Radix Angelicae Sinensis 70g, Radix Paeoniae Alba 60g, Cortex Acanthopancis 40g, Flos Rosae Chinensis 25g, Herba Cistanches 65g, Radix Codonopsis 20g, Radix Rhodiolae 25g, Radix Saniculae Astrantifoliae 35g, Rhizoma Polygonati 60g, Semen Euryales 50g, Colla Corii Asini 120g, Herba Lysimachiae Insignis 40g, Folium Mahoniae 25g, Herba Cynomorii 25g and Semen Sesami Nigrum 60g mixes, stir, add the water of 8.5kg, the pH value of water is regulated to be 3 with the hydrochloric acid that volumetric concentration is 5%, soak 1 hour ~ 2 hours, decoct 4 hours subsequently, decoction liquor is filtered, filtering residue adds the water of 6.5kg again, decoct 4 hours, decoction liquor is filtered, decoction liquor is merged, be 10% sodium hydroxide adjust ph to 7 by mass percentage concentration, obtain extracting solution, at extracting solution simmer down to 50 DEG C, relative density is the mastic of 1.20, be cooled to room temperature, add concentration be 95% ethanol reach 60% to alcohol content, 0 DEG C of cold preservation 12 hours, filter, filtrate reduced in volume reclaims ethanol, being concentrated into relative density at 50 DEG C is the mastic of 1.20, the thick paste of acquisition is added on the macroporous adsorptive resins of D101 type, the water of 2 times of column volumes is first adopted to rinse, be the ethanol elution of 30% at employing 5 times of column volume determining alcohols, 5 times of column volume determining alcohols are adopted to be the ethanol elution of 70% again, collect determining alcohol be 30% ethanol elution and determining alcohol be the ethanol elution of 70%, at being evaporated to 50 DEG C, relative density is 1.20, add isopyknic water, 0 DEG C of cold preservation 12 hours, filter, filtrate is concentrated except desolventizing, pulverize, dry, obtain Chinese medicine composition 2.
Embodiment 3
By Radix Panacis Quinquefolii 50g, Rhizoma Atractylodis Macrocephalae 35g, Fructus Jujubae 65g, Radix Rehmanniae Preparata 85g, Arillus Longan 40g, Radix Bupleuri 30g, Fructus Lycii 55g, Radix Polygoni Multiflori 85g, Radix Angelicae Sinensis 65g, Radix Paeoniae Alba 55g, Cortex Acanthopancis 35g, Flos Rosae Chinensis 20g, Herba Cistanches 60g, Radix Codonopsis 15g, Radix Rhodiolae 20g, Radix Saniculae Astrantifoliae 30g, Rhizoma Polygonati 55g, Semen Euryales 45g, Colla Corii Asini 115g, Herba Lysimachiae Insignis 35g, Folium Mahoniae 20g, Herba Cynomorii 20g and Semen Sesami Nigrum 55g mixes, stir, add the water of 7.5kg, the pH value of water is regulated to be 3 with the hydrochloric acid that volumetric concentration is 5%, soak 1 hour ~ 2 hours, decoct 4 hours subsequently, decoction liquor is filtered, filtering residue adds the water of 5.5kg again, decoct 4 hours, decoction liquor is filtered, decoction liquor is merged, be 10% sodium hydroxide adjust ph to 7 by mass percentage concentration, obtain extracting solution, at extracting solution simmer down to 50 DEG C, relative density is the mastic of 1.20, be cooled to room temperature, add concentration be 95% ethanol reach 60% to alcohol content, 0 DEG C of cold preservation 12 hours, filter, filtrate reduced in volume reclaims ethanol, being concentrated into relative density at 50 DEG C is the mastic of 1.20, the thick paste of acquisition is added on the macroporous adsorptive resins of D101 type, the water of 2 times of column volumes is first adopted to rinse, be the ethanol elution of 30% at employing 5 times of column volume determining alcohols, 5 times of column volume determining alcohols are adopted to be the ethanol elution of 70% again, collect determining alcohol be 30% ethanol elution and determining alcohol be the ethanol elution of 70%, at being evaporated to 50 DEG C, relative density is 1.20, add isopyknic water, 0 DEG C of cold preservation 12 hours, filter, filtrate is concentrated except desolventizing, pulverize, dry, obtain Chinese medicine composition 3.
Embodiment 4 blood-enriching oral liquid 1
25g sodium hydroxide is dissolved in distilled water and is prepared into the soda bath that mass percentage concentration is 10%, slowly add 50g ferrous porphyrin (Hui Kang source, Beijing bio tech ltd provides) subsequently, be stirred to and dissolve completely, obtain solution, by 75g brown sugar, 20g vitamin C, 20g vitamin B
2slowly add in the solution obtained above with Chinese medicine composition 1 prepared by 175g embodiment 1, stir completely, solution ph regulated value 7,0 DEG C of cold preservation 12 hours, filter, with distilled water diluting to 500ml, 70 DEG C of hot embeddings, 121 DEG C of autoclavings, lamp inspection, inspection, packaging.
Embodiment 5 blood-enriching oral liquid 2
25g sodium hydroxide is dissolved in distilled water and is prepared into the soda bath that mass percentage concentration is 10%, slowly add 50g ferrous porphyrin (Hui Kang source, Beijing bio tech ltd provides) subsequently, be stirred to and dissolve completely, obtain solution, by 75g brown sugar, 20g vitamin C, 20g vitamin B
2slowly add in the solution obtained above with Chinese medicine composition 2 prepared by 175g embodiment 2, stir completely, solution ph regulated value 7,0 DEG C of cold preservation 12 hours, filter, with distilled water diluting to 500ml, 70 DEG C of hot embeddings, 121 DEG C of autoclavings, lamp inspection, inspection, packaging.
Embodiment 6 blood-enriching oral liquid 3
25g sodium hydroxide is dissolved in distilled water and is prepared into the soda bath that mass percentage concentration is 10%, slowly add 50g ferrous porphyrin (Hui Kang source, Beijing bio tech ltd provides) subsequently, be stirred to and dissolve completely, obtain solution, by 75g brown sugar, 20g vitamin C, 20g vitamin B
2slowly add in the solution obtained above with Chinese medicine composition 3 prepared by 175g embodiment 3, stir completely, solution ph regulated value 7,0 DEG C of cold preservation 12 hours, filter, with distilled water diluting to 500ml, 70 DEG C of hot embeddings, 121 DEG C of autoclavings, lamp inspection, inspection, packaging.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (3)
1. a Chinese medicine composition for double QI invigorating of enriching blood, is characterized in that: the crude drug of described Chinese medicine composition comprises Radix Panacis Quinquefolii, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Radix Rehmanniae Preparata, Arillus Longan, Radix Bupleuri, Fructus Lycii, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Acanthopancis, Flos Rosae Chinensis, Herba Cistanches, Radix Codonopsis, Radix Rhodiolae, Radix Saniculae Astrantifoliae, Rhizoma Polygonati, Semen Euryales, Colla Corii Asini, Herba Lysimachiae Insignis, Folium Mahoniae, Herba Cynomorii and Semen Sesami Nigrum.
2. Chinese medicine composition as claimed in claim 1, is characterized in that: in described Chinese medicine composition, the weight of each raw material is respectively Radix Panacis Quinquefolii 45 weight portion ~ 55 weight portion, the Rhizoma Atractylodis Macrocephalae 30 weight portion ~ 40 weight portion, Fructus Jujubae 60 weight portion ~ 70 weight portion, Radix Rehmanniae Preparata 80 weight portion ~ 90 weight portion, Arillus Longan 35 weight portion ~ 45 weight portion, Radix Bupleuri 30 weight portion ~ 40 weight portion, Fructus Lycii 50 weight portion ~ 60 weight portion, Radix Polygoni Multiflori 80 weight portion ~ 90 weight portion, Radix Angelicae Sinensis 60 weight portion ~ 70 weight portion, the Radix Paeoniae Alba 50 weight portion ~ 60 weight portion, Cortex Acanthopancis 35 weight portion ~ 45 weight portion, Flos Rosae Chinensis 20 weight portion ~ 30 weight portion, Herba Cistanches 55 weight portion ~ 65 weight portion, Radix Codonopsis 15 weight portion ~ 25 weight portion, Radix Rhodiolae 20 weight portion ~ 30 weight portion, Radix Saniculae Astrantifoliae 30 weight portion ~ 40 weight portion, Rhizoma Polygonati 55 weight portion ~ 65 weight portion, Semen Euryales 45 weight portion ~ 55 weight portion, Colla Corii Asini 110 weight portion ~ 120 weight portion, Herba Lysimachiae Insignis 35 weight portion ~ 45 weight portion, Folium Mahoniae 20 weight portion ~ 30 weight portion, Herba Cynomorii 20 weight portion ~ 30 weight portion and Semen Sesami Nigrum 50 weight portion ~ 60 weight portion.
3. Chinese medicine composition as claimed in claim 1 or 2, it is characterized in that: in described Chinese medicine composition, the weight portion of each raw material is Radix Panacis Quinquefolii 50 weight portion, the Rhizoma Atractylodis Macrocephalae 35 weight portion, Fructus Jujubae 65 weight portion, Radix Rehmanniae Preparata 85 weight portion, Arillus Longan 40 weight portion, Radix Bupleuri 35 weight portion, Fructus Lycii 55 weight portion, Radix Polygoni Multiflori 85 weight portion, Radix Angelicae Sinensis 65 weight portion, the Radix Paeoniae Alba 55 weight portion, Cortex Acanthopancis 40 weight portion, Flos Rosae Chinensis 25 weight portion, Herba Cistanches 60 weight portion, Radix Codonopsis 20 weight portion, Radix Rhodiolae 25 weight portion, Radix Saniculae Astrantifoliae 35 weight portion, Rhizoma Polygonati 60 weight portion, Semen Euryales 50 weight portion, Colla Corii Asini 115 weight portion, Herba Lysimachiae Insignis 40 weight portion, Folium Mahoniae 25 weight portion, Herba Cynomorii 25 weight portion and Semen Sesami Nigrum 55 weight portion.
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| CN107468899A (en) * | 2017-09-25 | 2017-12-15 | 宁国平衡健康管理有限公司 | One kind is enriched blood ball and preparation method thereof |
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| CN107468899A (en) * | 2017-09-25 | 2017-12-15 | 宁国平衡健康管理有限公司 | One kind is enriched blood ball and preparation method thereof |
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