CN103272199B - Frostbite treatment medicine - Google Patents

Frostbite treatment medicine Download PDF

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Publication number
CN103272199B
CN103272199B CN201310212582.5A CN201310212582A CN103272199B CN 103272199 B CN103272199 B CN 103272199B CN 201310212582 A CN201310212582 A CN 201310212582A CN 103272199 B CN103272199 B CN 103272199B
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parts
radix
medicine
radix paeoniae
cortex
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CN201310212582.5A
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CN103272199A (en
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刘建飞
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刘建飞
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Abstract

The invention relates to a frostbite treatment medicine. The medicine is characterized by being prepared from the following raw materials in parts by weight: 13-17 parts of radix astragali, 10-14 parts of ramulus cinnamomi, 10-14 parts of cinnamon, 10-14 parts of frankincense, 8-12 parts of angelica sinensis, 8-12 parts of radix saposhnikoviae, 8-12 parts of pepper, 8-12 parts of cortex phellodendri chinensis, 8-11 parts of liquorice, 8-11 parts of folium artemisiae argyi, 8-11 parts of ginger, 6-8 parts of schizonepeta, 6-8 parts of radix paeoniae alba, 6-8 parts of radix paeoniae rubra, 6-8 parts of herba asari, 4-6 parts of safflower, 4-6 parts of camphor and 500-700 parts of 75% alcohol. The medicine has the advantages of quick effect, obvious curative effect, small side effect and low cost, and is convenient to operate; and clinic researches prove that the effective rate of the medicine for treating first-level frostbite and secondary-level frostbite is 100%.

Description

A kind of medicine for the treatment of cold injury
Technical field
The present invention relates to technical field of traditional Chinese medicine pharmacy, particularly relate to a kind of medicine for the treatment of cold injury.
Background technology
Cold injury refers to endures cold and the formed damage when reducing of local blood when soft tissue, when skin temperature drops to-2 ℃, cold injury just may occur, temperature cold injury incidence rate in the time of-25 ℃~-30 ℃ is the highest, according to degree of injury, be divided into: cold injury once: show as erythema, edema, skin paralysis and of short duration pain, skin lesion can recover completely, only with slight desquamation; Two degree cold injury: take obvious hyperemia, edema and vesicle as feature, bleb liquid is limpid; Skin lesion can heal, but can leave long-term sensory nerve pathological changes, often with obvious cold allergy; Three degree cold injury: comprise the damage of corium holostrome, form or wax-like, dry, mummy sample skin with blood blister; Tissue is lost, prognosis mala; Four degree cold injury: the thorough forfeiture of skin holostrome, comprises and the destruction of skin, muscle, tendon and skeleton can cause amputation.
At present, the medicine for the treatment of cold injury once, two degree cold injury is more, but exist, treatment time is long, effect is undesirable, side effect is large, the high deficiency of drug price.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of medicine for the treatment of cold injury, the present invention is applicable to treat once cold injury, two degree cold injury, and the present invention has advantages of instant effect, evident in efficacy, side effect is little, cost is low, it is easy to prepare.
A medicine for the treatment of cold injury, is characterized in that: the crude drug by following weight portion is made: Radix Astragali 13-17 part, Ramulus Cinnamomi 10-14 part, Cortex Cinnamomi 10-14 part, Olibanum 10-14 part, Radix Angelicae Sinensis 8-12 part, Radix Saposhnikoviae 8-12 part, Fructus Piperis 8-12 part, Cortex Phellodendri 8-12 part, Radix Glycyrrhizae 8-11 part, Folium Artemisiae Argyi 8-11 part, Rhizoma Zingiberis Recens 8-11 part, Herba Schizonepetae 6-8 part, Radix Paeoniae Alba 6-8 part, Radix Paeoniae Rubra 6-8 part, Herba Asari 6-8 part, Flos Carthami 4-6 part, Camphora 4-6 part, 75% ethanol 500-700 part.
The medicine of described treatment cold injury, is characterized in that: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 12 parts of Cortex Cinnamomis, 12 parts of Olibanums, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Saposhnikoviaes, 10 parts, Fructus Piperis, 10 parts of Cortex Phellodendris, 9 parts, Radix Glycyrrhizae, 9 parts of Folium Artemisiae Argyis, 9 parts, Rhizoma Zingiberis Recens, 7 parts of Herba Schizonepetae, 7 parts of the Radix Paeoniae Albas, 7 parts of Radix Paeoniae Rubra, 7 parts of Herba Asaris, 5 parts, Flos Carthami, 5 parts of Camphoras, 600 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury, comprises the following steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali taking, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soak 10 days, after filtration, obtain medicinal liquid.
Usage and consumption: with cotton swab dip in liquid medicine, be applied to cold injury place, every day 3-4 time.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
The Radix Astragali: meridian distribution of property and flavor: sweet, tepor; Effect: polishing consolidating superficial resistance, holder skin ulcer granulation promoting.
Ramulus Cinnamomi: meridian distribution of property and flavor: acrid, sweet, warm, GUIXIN, lung, urinary bladder channel; Diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Cortex Cinnamomi: meridian distribution of property and flavor: pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel; Effect: mend that fire is supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
Olibanum: meridian distribution of property and flavor: pungent, hardship, tepor; GUIXIN, liver, spleen channel; Effect: blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation.
Radix Angelicae Sinensis: meridian distribution of property and flavor: sweet, pungent, warm; Return liver, the heart, spleen channel; Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.
Radix Saposhnikoviae: meridian distribution of property and flavor: pungent, sweet, tepor, return bladder, lung, spleen, liver; Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.
Fructus Piperis: meridian distribution of property and flavor: pungent, heat, returns stomach, large intestine channel; Effect: warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.
Cortex Phellodendri: meridian distribution of property and flavor: hardship, cold; Return kidney, urinary bladder channel; Effect: heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.
Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Folium Artemisiae Argyi: meridian distribution of property and flavor: acrid, bitter, warm, slightly poisonous, return liver,spleen,kidney warp; Effect: dispersing cold for relieving pain, warming the meridian for stopping bleeding.
Rhizoma Zingiberis Recens: meridian distribution of property and flavor: pungent, tepor, returns lung, spleen, stomach warp; Effect: the cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.
Herba Schizonepetae: meridian distribution of property and flavor: pungent, tepor, return lung, Liver Channel; Effect: the loose wind that induces sweat, rash.
The Radix Paeoniae Alba: meridian distribution of property and flavor: be slightly cold, bitter, sour, return liver, spleen channel; Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Radix Paeoniae Rubra: meridian distribution of property and flavor: be slightly cold, hardship, return Liver Channel; Effect: clearing away heat and cooling blood, eliminating stasis to stop pain.
Herba Asari: meridian distribution of property and flavor: pungent, warm, GUIXIN, lung, kidney channel; Effect: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.
Flos Carthami: meridian distribution of property and flavor: pungent, warm, GUIXIN, Liver Channel; Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Camphora: meridian distribution of property and flavor: pungent, heat; GUIXIN, spleen channel; Effect: sensible, parasite killing, pain relieving, wards off dirty.
Above-mentioned each crude drug and the made medicinal liquid of proportioning thereof for the present invention, have warming the meridian and promoting blood circulation, the cold expelling stasis of blood, removing damp to relieve itching, anti-inflammation alive, hold back the effect of creation flesh, thereby reach the object for the treatment of cold injury.
The beneficial effect that the present invention compared with prior art had advantages of is: the present invention has instant effect, evident in efficacy, side effect is little, cost is low, it is easy to prepare; Through clinical verification, the present invention is 100% for treating the once effective percentage of cold injury, two degree cold injury.
The specific embodiment
Embodiment 1:
A medicine for the treatment of cold injury, is characterized in that: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 12 parts of Cortex Cinnamomis, 12 parts of Olibanums, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Saposhnikoviaes, 10 parts, Fructus Piperis, 10 parts of Cortex Phellodendris, 9 parts, Radix Glycyrrhizae, 9 parts of Folium Artemisiae Argyis, 9 parts, Rhizoma Zingiberis Recens, 7 parts of Herba Schizonepetae, 7 parts of the Radix Paeoniae Albas, 7 parts of Radix Paeoniae Rubra, 7 parts of Herba Asaris, 5 parts, Flos Carthami, 5 parts of Camphoras, 600 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury, comprises the following steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali taking, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soak 10 days, after filtration, obtain medicinal liquid.
Embodiment 2:
A medicine for the treatment of cold injury, is characterized in that: the crude drug by following weight portion is made: 13 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 10 parts of Cortex Cinnamomis, 10 parts of Olibanums, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Saposhnikoviaes, 8 parts, Fructus Piperis, 8 parts of Cortex Phellodendris, 8 parts, Radix Glycyrrhizae, 8 parts of Folium Artemisiae Argyis, 8 parts, Rhizoma Zingiberis Recens, 6 parts of Herba Schizonepetae, 6 parts of the Radix Paeoniae Albas, 6 parts of Radix Paeoniae Rubra, 6 parts of Herba Asaris, 4 parts, Flos Carthami, 4 parts of Camphoras, 500 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury, comprises the following steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali taking, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soak 10 days, after filtration, obtain medicinal liquid.
Embodiment 3:
A medicine for the treatment of cold injury, is characterized in that: the crude drug by following weight portion is made: 17 parts of the Radixs Astragali, 14 parts of Ramulus Cinnamomi, 14 parts of Cortex Cinnamomis, 14 parts of Olibanums, 12 parts of Radix Angelicae Sinensis, 12 parts of Radix Saposhnikoviaes, 12 parts, Fructus Piperis, 12 parts of Cortex Phellodendris, 11 parts, Radix Glycyrrhizae, 11 parts of Folium Artemisiae Argyis, 11 parts, Rhizoma Zingiberis Recens, 8 parts of Herba Schizonepetae, 8 parts of the Radix Paeoniae Albas, 8 parts of Radix Paeoniae Rubra, 8 parts of Herba Asaris, 6 parts, Flos Carthami, 6 parts of Camphoras, 700 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury, comprises the following steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali taking, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soak 10 days, after filtration, obtain medicinal liquid.
Experimental example:
One, clinical data: adopt the present invention to treat once cold injury, two degree cold injury patient 66 examples, male 27 examples wherein, female's 39 examples, the oldest 65 years old, minimum 7 years old of age.
Two, clinical symptoms: cold injury once: erythema, edema, skin paralysis and pain, only with slight desquamation; Two degree cold injury: have hyperemia, edema and vesicle, bleb liquid is limpid, and pain, often with obvious cold allergy.
Three, Therapeutic Method: be applied to cold injury place, every day 3-4 time with cotton swab dip in liquid medicine.
Four, the standard of curative effect evaluation:
Cure: transference cure, lump dissipates, wound healing;
Take a turn for the better: symptom is obviously improved, wound surface is healing completely not;
Do not heal: symptom is not improved.
Five, model case:
1, Chen, female, 42 years old, annual winter all there is cold injury in hand, face, and Symptoms is the rounded aubergine edema of skin of face erythema, and hand swelling etc., are two degree cold injury; The medicine that uses treatment cold injury of the present invention after 7 days symptom obviously improve, recovery from illness in 15 days; Second Year winter, advise and continue to use this medicine, there is not again cold injury, follow up a case by regular visits to not recurrence in 3 years.
2, season so-and-so, man, 14 years old, all there is cold injury annual winter in ear, Symptoms is erythema, edema, skin paralysis and pain etc.; For cold injury once; The medicine that uses treatment cold injury of the present invention after 5 days symptom obviously improve, recovery from illness in 10 days, follows up a case by regular visits to not recurrence in 4 years.
Six, therapeutic outcome:
Adopt the present invention to treat once cold injury, two degree cold injury patient 66 examples, through the treatment of 10-20 days, wherein cure 61 examples, 5 examples that take a turn for the better, cure rate is 92%, effective percentage is 100%; Result shows, the present invention has advantages of instant effect, evident in efficacy, side effect is little.

Claims (3)

1. a medicine for the treatment of cold injury, is characterized in that: the crude drug by following weight portion is made: Radix Astragali 13-17 part, Ramulus Cinnamomi 10-14 part, Cortex Cinnamomi 10-14 part, Olibanum 10-14 part, Radix Angelicae Sinensis 8-12 part, Radix Saposhnikoviae 8-12 part, Fructus Piperis 8-12 part, Cortex Phellodendri 8-12 part, Radix Glycyrrhizae 8-11 part, Folium Artemisiae Argyi 8-11 part, Rhizoma Zingiberis Recens 8-11 part, Herba Schizonepetae 6-8 part, Radix Paeoniae Alba 6-8 part, Radix Paeoniae Rubra 6-8 part, Herba Asari 6-8 part, Flos Carthami 4-6 part, Camphora 4-6 part, 75% ethanol 500-700 part.
2. the medicine for the treatment of cold injury according to claim 1, is characterized in that: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 12 parts of Cortex Cinnamomis, 12 parts of Olibanums, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Saposhnikoviaes, 10 parts, Fructus Piperis, 10 parts of Cortex Phellodendris, 9 parts, Radix Glycyrrhizae, 9 parts of Folium Artemisiae Argyis, 9 parts, Rhizoma Zingiberis Recens, 7 parts of Herba Schizonepetae, 7 parts of the Radix Paeoniae Albas, 7 parts of Radix Paeoniae Rubra, 7 parts of Herba Asaris, 5 parts, Flos Carthami, 5 parts of Camphoras, 600 parts of 75% ethanol.
3. the preparation method of the medicine for the treatment of cold injury according to claim 1 and 2, comprises the following steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali taking, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soak 10 days, after filtration, obtain medicinal liquid.
CN201310212582.5A 2013-05-31 2013-05-31 Frostbite treatment medicine CN103272199B (en)

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CN104644986A (en) * 2015-02-06 2015-05-27 济南骄泰信息技术有限公司 Traditional Chinese medicine preparation for nursing and alleviating pains and itches caused by frostbite and preparation method thereof
CN104740565A (en) * 2015-03-22 2015-07-01 张晓利 Traditional Chinese medicine composition for treating cold injury
CN105106882A (en) * 2015-08-18 2015-12-02 李际涛 Traditional Chinese medicine composition for treating frostbite
CN108159385A (en) * 2018-03-06 2018-06-15 黄振忠 A kind of drug for treating frostbite

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Inventor after: Zhang Mei

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Inventor before: Liu Jianfei

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Effective date of registration: 20160729

Address after: 262700 Shandong street health city of Weifang province Shouguang City, No. 43

Patentee after: Zhang Mei

Address before: Tu Shan Xi Lu Yuhui District 233000 Anhui city of Bengbu province No. 1709 COFCO Tu thermoelectric boiler workshop production department

Patentee before: Liu Jianfei

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20141112

Termination date: 20170531