CN104523838A

CN104523838A - Medicine for treating varicose veins of lower limbs

Info

Publication number: CN104523838A
Application number: CN201510034903.6A
Authority: CN
Inventors: 孙伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-01-25
Filing date: 2015-01-25
Publication date: 2015-04-22

Abstract

The invention relates to a medicine for treating varicose veins of lower limbs. The medicine is prepared from the following raw materials in parts by weight: 6 parts of cassia twig, 9 parts of salviae miltiorrhizae, 9 parts of caulis spatholobi and 10 parts of leech. The cassia twig in the prescription is pungent, sweet and mild, belongs to the heat, lung and bladder channels, and has the efficacies of expelling the evils in muscles by means of diaphoresis, warming the meridians, supporting yang, fluidizing gas, balancing pulse and depressing qi; the salviae miltiorrhizae belongs to the heart and liver channels, and has the efficacies of removing stasis to ease pain, activating blood to promote menstruation, clearing away the heart-fire and relieving restlessness; the caulis spatholobi belongs to the liver and kidneys channels, and has the efficacies of enriching blood, activating blood circulation and dredging collaterals; the leech belongs the liver channels and has the efficacies of relieving blood, remove blood stasis and restoring menstrual flow; and the medicines are combined and work together to achieve the efficacies of activating blood circulation, remove blood stasis, dredging collaterals and relieving pain. A clinical experiment proves that the medicine can be safely and effectively applied to treatment of the varicose veins of lower limbs.

Description

A kind of medicine being used for the treatment of varicose veins of the lower extremity

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of Chinese medicine being used for the treatment of varicose veins of the lower extremity.

Background technology

Varicose veins of the lower extremity be patient's lower limb tube wall become book, superficial vein is thicker, in Lumbricus shape or lumps be the main manifestations of varicose veins of the lower extremity.The many superficial vein blood flow reflux caused due to superficial vein first pair of valve (stock saphena valve) incompetence of the cause of disease, increase veins of lower extremity pressure and cause.Secondly, geneogenous wall of vein weakness is also major reason, and patient is often associated with the whole body or circumscribed wall of vein defect, when vein pressure increases, just produces tortuous, the expansion of vein.Finally, stand for a long time, fat and abdominal pressure etc. because of procatarxis can increase that vein pressure all can increase that varicosis development occurs may.

This disease incidence is early stage, mostly is the lower limb swollen discomfort of acid and dull pain sense, has limbs sense of heaviness simultaneously, easily weak.How above-mentionedly behind station for a long time feel to increase the weight of, then can be alleviated by flat sleeping, limb lifting.Pathological changes middle and late stage, wall of vein is impaired, vein protuberance, expansion, tortuous, in Lumbricus sample outward appearance, with the traveling of medial leg great saphenous vein, district is obvious.Course of disease elder, limb skin then occurs that trophism changes, and as desquamation, pruritus, pigmentation etc., even forms eczema and ulcer.Along with the differentiation of the state of an illness, can with the symptom such as pain, lower extremity swelling and distension, stasis dermatitis, superficial vein thrombosis of blood vessel traveling.

Medical material present Research involved in the present invention is as follows:

Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Spring, Xia Erji gather, and except defoliation, dry, or section is dried.[process of preparing Chinese medicine] removing impurity, slightly steeps, cleans, run through, shave, dry.This product is similar round, oval sheet or difform section.Skin zone's rufous, surface is visible point-like hole skin or vertical crest line sometimes, woody part yellow-white or light yellowish brown, marrow similar round or be slightly square.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.[usage and dosage] 3 ~ 9g.[storage] puts shady and cool dry place.

Radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bunge..Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.[usage and dosage] 6 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[storage] puts dry place.

Caulis Spatholobi [source] this product is the dry rattan of leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind) Spatholobus suberectus Dunn.Autumn, season in winter two gather, and removing branch and leaf, section, dries.[process of preparing Chinese medicine] removing impurity, clean, run through, chopping, dries.[nature and flavor] are bitter, sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] enriches blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.[usage and dosage] 9 ~ 15g.[storage] puts aeration-drying place, and mildew-resistant is mothproof.

Hirudo [source] this product is the dry body of Hirudinidae animal whitmania Whitmania pigra Whitman, Hirudo Hirudo nipponica Whitman or Folium Salicis Babylonicae Hirudo Whit-mania acranulata Whitman.Summer, Qiu Erji catch, and scald dead, dry or cold drying with boiling water.[process of preparing Chinese medicine] Hirudo: clean, cutting, dry.[nature and flavor] are salty, bitter, flat; Slightly poisonous.[return through] returns Liver Channel.[function cures mainly] removing blood stasis, removing blood stasis, stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.[usage and dosage] 5 ~ 15g.[attention] anemia of pregnant woman and forbidding without blood stasis person.[storage] puts dry place, mothproof.

Summary of the invention

The present invention aims to provide a kind of medicine being used for the treatment of varicose veins of the lower extremity, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to varicose veins of the lower extremity treatment.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a medicine for varicose veins of the lower extremity, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Ramulus Cinnamomi 6 parts, Radix Salviae Miltiorrhizae 9 parts, Caulis Spatholobi 9 parts, Hirudo 10 parts.

Inventor is according to the Couple herbs had the deep influence of a scholarly family, think that varicose veins of the lower extremity belongs to the category such as the traditional Chinese medical science " BI-syndrome involved the blood vessels ", " superficial obstructive phlebitis ", primary disease is because natural endowment is not enough, muscle arteries and veins is weak, and walking for a long time standing for a long time, overworked in addition, further damage muscle arteries and veins, so that passages through which vital energy circulates do not conform to, QI-blood circulation is smooth, blood stop up under, the expansion of congestion retardance venation is full, with the passing of time staggeredly tortuously to form, or deficiency of vital energy cold coagulation causes capable operations of gas freely, qi stagnation hemagglutination, stasis blocking blood vessels meridians, the stasis of blood is obstructed for a long time, and ischemia ulceration infects, notably recurrent exerbation.Treatment according to state of an illness determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, should take the principle for the treatment of of blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian.Ramulus Cinnamomi in side, acrid, sweet, warm; GUIXIN, lung, urinary bladder channel, have diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, effect of the flat gas that spins; Radix Salviae Miltiorrhizae, GUIXIN, Liver Channel, stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness; Caulis Spatholobi, returns liver, kidney channel, enriches blood, invigorate blood circulation, dredging collateral; Hirudo returns Liver Channel, removing blood stasis, and removing blood stasis stimulates the menstrual flow.All medicines share, and play effect of blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain altogether.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

In JIUYUE, 2011 collects the patient of 120 routine varicose veins of the lower extremity in August ,-2013, is divided into 2 groups at random.Treatment group 60 example, man 36 example, female 24 example, age 26-50 year, the mean age is 44.5 years old, course of disease 1-8; Matched group 60 example, man 32 example, female 28 example, age 25-50 year, the mean age is 45.0 years old, course of disease 1.5-7.5.Two groups of Genders, ages compare with the course of disease, do not have significant difference, have comparability.

2 diagnostic methods

Two groups of patients all carry out the test of clinical great saphenous vein valvular function, color ultrasound examination, Deep venou Patency test and the test of communicating veins valvular function, all cases gets rid of congenital vascular malformation, deep vein thrombosis of lower extremity and Budd-Chairi syndrome etc. and primary deep venous valvular inadequacy patient.

3, research method

3.1 Therapeutic Method

Treatment group takes the decoct that the present invention obtains according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.

Matched group vascular tablet for recovery, daily 3 times, each serving with 4, correctly takes to specifications.

All treat 1 month for two groups.

3.2 statistical method

Adopt SPSS18.0 statistics software data processing.

4, therapeutic outcome

4.1 efficacy evaluation methods

Curative effect is divided into healing completely, part healing and recurrence 3 ranks: patient's naked eyes have no varicosis, fundamental symptoms disappears or is improved, without complication, the disappearance of target vein is for cure completely; The visible varicosis in a small amount of patient, fundamental symptoms disappear or improve, target vein segment is incompressible, segment section is inaccessible, caliber reduces reflux < 1s for part healing, patient's vein unchanged or comparatively treatment before situation increase the weight of, fundamental symptoms is unchanged or increase the weight of, and not closed through 2 months check target veins, caliber is unchanged, reflux >1s is recurrence.

4.2 liang of group curative effects

After the treatment of month, 8 examples of wherein treatment group recovery from illness, 36 effective examples, effective 12 examples, invalid 4 examples, total effective rate is 93.3%; Matched group recovery from illness 3 example, effective 24 examples, effective 23 examples, invalid 10 examples, total effective rate is 83.3%.Two groups of total effective rates compare, and treatment group and matched group exist significant significant difference, P<0.05.

4.3 untoward reaction

Over the course for the treatment of, there is dizzy, heart-throb person 2 example in matched group to patient, treatment group has no obvious adverse reaction.

Visible, the medicine that the present invention obtains can safe and effective treatment varicose veins of the lower extremity, has good medical science promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Ramulus Cinnamomi 6 grams, Radix Salviae Miltiorrhizae 9 grams, Caulis Spatholobi 9 grams, Hirudo 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of varicose veins of the lower extremity.Oral, every bu morning, noon and afternoon take for three times.

Embodiment 2

Take: Ramulus Cinnamomi 6 grams, Radix Salviae Miltiorrhizae 9 grams, Caulis Spatholobi 9 grams, Hirudo 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of varicose veins of the lower extremity.Oral, daily once.

Embodiment 3

Take: Ramulus Cinnamomi 6 grams, Radix Salviae Miltiorrhizae 9 grams, Caulis Spatholobi 9 grams, Hirudo 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of varicose veins of the lower extremity.Oral, every bu is taken for twice sooner or later.

Claims

1. be used for the treatment of a medicine for varicose veins of the lower extremity, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Ramulus Cinnamomi 6 parts, Radix Salviae Miltiorrhizae 9 parts, Caulis Spatholobi 9 parts, Hirudo 10 parts.