CN103285049B - External drug for treating bums or scalds and preparation method thereof - Google Patents
External drug for treating bums or scalds and preparation method thereof Download PDFInfo
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- CN103285049B CN103285049B CN201310203352.2A CN201310203352A CN103285049B CN 103285049 B CN103285049 B CN 103285049B CN 201310203352 A CN201310203352 A CN 201310203352A CN 103285049 B CN103285049 B CN 103285049B
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- scalds
- raw material
- external preparation
- bums
- treatment
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- 206010053615 Thermal burn Diseases 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims abstract description 31
- 239000003814 drug Substances 0.000 title abstract description 10
- 229940079593 drug Drugs 0.000 title abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 23
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 13
- 239000000843 powder Substances 0.000 claims abstract description 8
- 241001290564 Fimbristylis Species 0.000 claims description 18
- 238000003763 carbonization Methods 0.000 claims description 4
- 208000027418 Wounds and injury Diseases 0.000 abstract description 21
- 206010052428 Wound Diseases 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 11
- 238000011084 recovery Methods 0.000 abstract description 5
- 231100000241 scar Toxicity 0.000 abstract description 5
- 208000003656 Electric Burns Diseases 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 208000009043 Chemical Burns Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 240000005893 Pteridium aquilinum Species 0.000 abstract 1
- 235000009936 Pteridium aquilinum Nutrition 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 description 8
- 238000004140 cleaning Methods 0.000 description 4
- 210000000416 exudates and transudate Anatomy 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
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- 238000005516 engineering process Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 206010020718 hyperplasia Diseases 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 210000000589 cicatrix Anatomy 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
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- 210000003371 toe Anatomy 0.000 description 2
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- 208000012260 Accidental injury Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
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- 206010040799 Skin atrophy Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 210000003423 ankle Anatomy 0.000 description 1
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- 230000004087 circulation Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- SEACYXSIPDVVMV-UHFFFAOYSA-L eosin Y Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C([O-])=C(Br)C=C21 SEACYXSIPDVVMV-UHFFFAOYSA-L 0.000 description 1
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- 231100000206 health hazard Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 235000000396 iron Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
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Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an external drug for treating bums or scalds and a preparation method thereof. An external preparation for treating the bums or scalds is prepared by carrying out raw material treatment, grinding and the like on the following components in a formula by mass percent: 90-98% of bracken powder a), and 2-10% of borneol b. The external preparation for treating the bums or scalds is used for treating various bums or scalds, for example, electric burns, chemical burns, cauterized wounds of motorcycle exhaust pipes, and various oil bums or scalds, and has excellent effect. The external preparation disclosed by the invention is free of toxic and side effect, free of allergy, short in treatment coarse, fast to become effective, free of a scar after recovery, and the like by clinical application for a plurality of times.
Description
Technical field
The present invention relates to a kind of exterior use scald, burn medicine, be specifically related to a kind of external preparation for the treatment of scalds and burns and preparation method thereof.
Background technology
Burn or scald mainly refer to skin, mucosa, the even infringement of deep tissue that heating power, chemical substance, electric energy, lonizing radiation etc. cause.Wherein skin heat injury (as flame, boiled water etc.) is the most common.According to statistics, because of the death toll of unexpected injury, burn is only second to vehicle accident, comes second every year, and also has a large amount of wounded to merge burn in vehicle accident injury.China's burn annual morbidity is about 1.5%~2%, approximately has every year 2000 ten thousand people to suffer to burn in various degree, and wherein approximately 5% burn patient needs hospitalization.Burn healthhazard had both comprised physiological, also comprised psychological.According to burn injury, to the different degree of depth of skin, can roughly burn be once divided into two degree, three degree and fourth-degree burns.When if the wound surface of just scalding or burning is very little, as long as keep clean, in the just possibility spontaneous recovery of short time class.If the impaired area of lower floor's corium is larger, if missed the best time, will cause a large amount of skin hyperplasias and atrophoderma, this situation usually needs to carry out skin grafting, yet skin grafting needs expensive Operation Fee, be that average family is unaffordable, some family goes bankrupt or broke even for this reason; And many times cannot find healthy cortex source to cause operation to delay again and again, finally to the stage that cannot repair.
The treatment that Hospitals at Present is conventional is scalded, the medicament categories of burn is a lot, but the medical material cost of these drug uses is high, complex manufacturing technology, and the price of medicine is also somewhat expensive, and these medicines curative effect in therapeutic process is also different with effect; And burn or medicament for treating scald that hospital is used all can not be avoided at affected part scar.
Summary of the invention
For overcoming the defect of prior art, the object of the present invention is to provide a kind of external preparation for the treatment of scalds and burns, formula is simple, raw material is easy to get, can be now with the current, be used for the treatment of burn, scald, have no side effect, without irritated, subside a swelling fast, good effect, and preventing from scar.
Another object of the present invention is to provide a kind of preparation method for the treatment of the external preparation of scalds and burns.
The technical solution adopted in the present invention is as follows for achieving the above object:
Treat an external preparation for scalds and burns, it is to be prepared from following raw material:
A) Herba Fimbristylis dichotomae powder
B) Borneolum Syntheticum
Its Raw a) and raw material b) mass percent in formula is respectively 90-98% and 2-10%.
In the present invention, adopt Herba Fimbristylis dichotomae as primary raw material, because Herba Fimbristylis dichotomae is cool in nature, acrid in the mouth, sweet, puckery; Have clearing away heat-fire removing pathogenic heat from blood and toxic substance from the body, heat is ironed in burn and scald Symptoms part, pain, and blood stasis edema, etc. effect.In the present invention the Main Function of Herba Fimbristylis dichotomae be purging fire and cooling blood removing toxic substances, disperse circulation of qi promoting, invigorate blood circulation, matter profit grows the effects such as dry, astringent or styptic treatment for spontaneous sweating; Borneolum Syntheticum nature and flavor are pungent, bitter, be slightly cold, and have and have one's ideas straightened out, refreshment, the effects such as clearing away heat to alleviate pain.Inventor finds through research, and burn and scald is hindered its fur exactly, and burn and scald there will be dry burnt convulsion pain after four or five days, and Herba Fimbristylis dichotomae and Borneolum Syntheticum are combined with, and can effectively promote wound surface incrustation healing, greatly improved curative effect, had shortened the course for the treatment of, and more without cicatrix.
As of the present invention preferred embodiment a kind of, the external preparation Raw of described treatment scalds and burns a) and raw material b) mass percent in formula is respectively 98% and 2%.
As of the present invention preferred embodiment a kind of, the fineness of described Herba Fimbristylis dichotomae powder is 80-200 order, Shi You Herba Fimbristylis dichotomae stem or/and Herba Fimbristylis dichotomae leaf portion grind and to form.
A preparation method for the treatment of the external preparation of scalds and burns, it comprises the following steps:
1) raw material is processed: select fresh fiddlehead, after dehydrate or carbonization, shred;
2) grind: the raw material in step 1) and Borneolum Syntheticum are ground altogether in container.
As a preferred scheme of the present invention, the stem that the raw material of choosing in described step 1) is fresh fiddlehead is or/and leaf portion.
Using method of the present invention is, in 8 days at burn or after scalding, after cleaning affected part, smears external preparation of the present invention, 2 times on the one, uses and fully recovers to affected part continuously.
Compared to existing technology, beneficial effect of the present invention is: the external preparation for the treatment of scalds and burns of the present invention is for various burn and scald, and as electric burn, chemicals is burnt, and motorcycle exhaust pipe irons wound, and various oils burn and scald, all has excellent effect; External preparation of the present invention is through time clinical practice, and demonstration has no side effect, nothing is irritated, and has short treating period, and instant effect, does not have the advantages such as cicatrix more afterwards.
Below in conjunction with concrete embodiment, the present invention is described in further detail.
The specific embodiment
It is below the concrete cited specific embodiment of the present invention.
Embodiment 1
Treat an external preparation for scalds and burns, it is to be prepared from following raw material:
A) Herba Fimbristylis dichotomae powder
B) Borneolum Syntheticum
Raw material a) and raw material b) mass percent in formula is respectively 90% and 10%; Its preparation method is as follows: select fresh Herba Fimbristylis dichotomae, remove root, after cleaning, dehydration carbonization chopping, then grinds altogether with Borneolum Syntheticum.
Embodiment 2
Treat an external preparation for scalds and burns, it is to be prepared from following raw material:
A) Herba Fimbristylis dichotomae powder
B) Borneolum Syntheticum
Raw material a) and raw material b) mass percent in formula is respectively 95% and 5%.Its preparation method is as follows: selects fresh Herba Fimbristylis dichotomae, removes root, and dehydrate after cleaning, chopping, then grinds altogether with Borneolum Syntheticum.
Embodiment 3
Treat an external preparation for scalds and burns, it is to be prepared from following raw material:
A) Herba Fimbristylis dichotomae powder
B) Borneolum Syntheticum
Its Raw a) and raw material b) mass percent in formula is respectively 98% and 2%; Its preparation method is as follows: selects fresh Herba Fimbristylis dichotomae, removes root, and after cleaning, carbonization, chopping, then grinds altogether with Borneolum Syntheticum.
Application Example 1
Chen, man, 40 years old now, people from Liuzhou, two lower limbs and ankle, instep, toes, burn reaches 95%, examination in hospital is decided to be III degree deep burn, two shanks, and instep, toes, edema is shinny, liquid body exudate is more, and hurt like hell can not be fallen asleep round the clock, and wound surface is utterly putrid enters order, has pungent abnormal flavour; Through sterilization, clean, use the external preparation of the treatment scalds and burns of embodiment 1, do not need wrapping, allow affected part expose wound surface, and exhort that patient does not touch, do not eat stimulating food thing, lie up, edema disappears, and water has not flowed yet, because convulsion alleviation of pain is few, fall asleep also easy, continual cure 3 days, wound surface incrustation 85%, by recovery from illness in a week, after eight months, to checking affected part, there is no hypertrophy vestige.
Application Example 2
Lee, man, 48 years old now, Hunan spring sun people, electrician, on May 11st, 2011 is because of misoperation, carelessness, by electric burn, at that time certain hospitalize one week, do not feel any better, through checking, left hand, the back of the hand, palm and the five fingers, all reached 95% by burn, edema, referring to, by as mud, has obvious stream yellow fluid phenomenon.Pain is sent out at wound surface edge burnt, has difficulty in going to sleep, and sterile-processed wound surface, is used the external preparation of embodiment 2, and second day patient comes to change dressings and checks, edema disappears entirely, has not flowed yellow fluid, and wound edge is ruddy, through continual cure five days, and incrustation, rear conditioning one week, recovery from illness; There are no scar hyperplasia, recover former state, only have a small amount of skin eosine, after 1 year, check, loseed the vestige that has the wound of being subject to
Application Example 3
Mrs Li, 40 years old now, people from Guangxi, the Spring Festival in 2012, accidentally by chaffy dish meat soup, scalded, the right thigh knee joint shank first half is scalded 80% and is diagnosed as deep II degree burn wound, routine disinfection, process the residual skin of wound surface, and break all large vesicle, clean up, coat the external preparation of embodiment 2, second day, there is not edema phenomenon, wound surface does not have transudate yet, major part is dry, only has knee joint, there is a small amount of transudate, (because wanting movable in joint), through continuing with we, exhort that it is unmovable, reduce joint motion as far as possible, within the 3rd day, wound surface surrounding is ruddy, major part forms a scab, advise its rest of being in to walk about less, do not eat with acid and stimulating food group food, working work afterwards in 6 days, that after half a year, sees patient's happiness allows me check injured affected part, excellent, with injured before do not have difference.
Application Example 4
Mr. Chen, man, 38 years old now, people from Sichuan, the worker of wheel shop, during April in 2012 work on the scene on the 6th, because hanging the wire cable rupture of aluminum water, inclines aluminum water to go out to ground, by 800 degrees Celsius of aluminum scald volas.The end 2/3rds, is burned, wound surface ulcer, rotten, a maximum large 2mm
2deeply, belong to severe scald, through routine disinfection, clean wound surface, cut dead bark, remove dirt, edema is serious, instep is as steamed bun, and there is blue disease to resemble, the real severe case that belongs to, external preparation through being coated with embodiment 3 is after two days, check that edema fades, it is red that the colour of skin turns, hinder face major part dry, there is no transudate, successful takes a turn for the better, by top, continue medication treatment, the next day, changes dressings once, do not exhort and do housework, accomplish to lie up as far as possible, allow its wound surface fully expose, patient actively coordinates, through treatment in eight days, incrustation recovery from illness, working work in 12 days, after half a year, seeing patient checks, there is not any scar hyperplasia,
Above-mentioned embodiment is only the preferred embodiment of the present invention; can not limit the scope of protection of the invention with this, the variation of any unsubstantiality that those skilled in the art does on basis of the present invention and replacement all belong to the present invention's scope required for protection.
Claims (3)
1. an external preparation for the treatment of scalds and burns, is characterized in that: it is to be prepared from following raw material:
A) Herba Fimbristylis dichotomae powder
B) Borneolum Syntheticum
Its Raw a) and raw material b) mass percent in formula is respectively 90-98% and 2-10%;
It is prepared from as follows:
1) raw material is processed: select fresh fiddlehead, dehydrate or carry out shredding after carbonization;
2) raw material and Borneolum Syntheticum grinding: by step 1) grind altogether in container;
Described step 1) raw material of choosing in is that the stem of fresh fiddlehead is or/and leaf portion.
2. the external preparation for the treatment of scalds and burns according to claim 1, is characterized in that: its Raw a) and raw material b) mass percent in formula is respectively 98% and 2%.
3. the external preparation for the treatment of scalds and burns according to claim 1 and 2, is characterized in that: the fineness of described Herba Fimbristylis dichotomae powder is 80-200 order, Shi You Herba Fimbristylis dichotomae stem or/and Herba Fimbristylis dichotomae leaf portion grind and to form.
Priority Applications (1)
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CN201310203352.2A CN103285049B (en) | 2013-05-28 | 2013-05-28 | External drug for treating bums or scalds and preparation method thereof |
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CN201310203352.2A CN103285049B (en) | 2013-05-28 | 2013-05-28 | External drug for treating bums or scalds and preparation method thereof |
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CN103285049A CN103285049A (en) | 2013-09-11 |
CN103285049B true CN103285049B (en) | 2014-11-26 |
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CN106822335A (en) * | 2016-12-19 | 2017-06-13 | 牟德华 | It is a kind of to treat externally applied drug of scalds and burns and preparation method thereof |
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- 2013-05-28 CN CN201310203352.2A patent/CN103285049B/en not_active Expired - Fee Related
Non-Patent Citations (4)
Title |
---|
冰片水溶液治疗烫伤;吴义坤;《江苏医药》;19761231(第6期);第60页 * |
吴义坤.冰片水溶液治疗烫伤.《江苏医药》.1976,(第6期), * |
蕨菜产品的开发;薛志成;《农家科技》;20061231(第11期);第40页 * |
薛志成.蕨菜产品的开发.《农家科技》.2006,(第11期), * |
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