DK201670336A1 - A Barbados aloe scar eliminating ointment - Google Patents

A Barbados aloe scar eliminating ointment Download PDF

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Publication number
DK201670336A1
DK201670336A1 DKPA201670336A DKPA201670336A DK201670336A1 DK 201670336 A1 DK201670336 A1 DK 201670336A1 DK PA201670336 A DKPA201670336 A DK PA201670336A DK PA201670336 A DKPA201670336 A DK PA201670336A DK 201670336 A1 DK201670336 A1 DK 201670336A1
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Prior art keywords
scar
aloe
barbados aloe
eliminating
barbados
Prior art date
Application number
DKPA201670336A
Inventor
Xiaoying Liu
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Tingen Tech Co Ltd
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Publication of DK201670336A1 publication Critical patent/DK201670336A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

To overcome the defects of narrow applicable field and poor scar eliminating effect for current aloe scar eliminating medicines, the present invention provides a Barbados aloe scar eliminating ointment having good comprehensive pharmaceutical property and good healthcare effect. The Chinese medicine according to the present invention is prepared by taking Barbados aloe as main raw material, and combines the effects of traditional medicinal materials and research achievements of modern pharmacology. The Barbados aloe scar eliminating ointment comprises, by weight parts, peeled Barbados aloe 25-30, dark plum 10-15, kuh-seng 2-5, centipede 2-4, peeled cactus 5-10, borneol powder 1-6, Fritillaria 1-3, and pangolin 3-7. The Barbados aloe scar eliminating ointment provided in the present invention has the effect in eliminating scar, and has special effects for traumatic scar, pimple scar and hyperplastic scar.

Description

A BARBADOS ALOE SCAR ELIMINATING OINTMENT TECHNICAL FIELD
The present invention relates to a Barbados aloe scar eliminating ointment. BACKGROUND
Scar is a rough concept and is a general name for the change of appearance morphology and histopathology of normal skin tissue caused by various injuries. It is a normal and necessary physiological response during the natural recovery of wound or wound surface, and is also an inevitable result of the process of wound union. The essence of the scar is an abnormal and defective tissue with loss of normal tissue viability and without normal skin tissue structure or physiological function. The scar not only destroys body surface beauty, but also impedes the physiological functions of relevant organs or tissues, and even leads to deformity.
Barbados aloe leaf contains therein more than 160 ingredients such as anthraquinone, polysaccharides, amino acids, vitamins, minerals and the like. The combination of the multiple ingredients of the Barbados aloe results in the effects of diminishing inflammation, sterilization, mitigation, elimination of heat and swelling, softening skin, relieving pain, activating cells, and destroying abnormal cells. The treatment for wound with Barbados aloe can prevent affected part from bacterial infection, promote regeneration of skin tissue, and avoid scar to be left. Therefore, the Barbados aloe can not only treat bum (scald, fire bum, sunburn, etc.), but also treat wound (cut, traumatic injury, etc.), mosquito bite, frostbite and the like Barbados aloe as a sneeifie meriieine for bum has been wirielv srvreaH in folk long before, and it is called “scald grass” in many places of China. The Barbados aloe product is salable in Japan and USA because it can act as bum medicine. Mild bums can be treated with domestically-used aloe, whereas severe bums need to be treated in hospital. For the mild bums, the aloe can play an important role either for emergency processing or treatment. Even for the severe bums, the hospital treatment accompanied by oral administration and external application of aloe can promote recovery and eliminate scar; the key for treating soft tissue injury is activating blood circulation to dissipate stasis, and relieving swelling and pain. The aloe has the effect in diminishing inflammation, easing pain, and activating blood circulation to dissipate stasis. The aloe has also good effect for treating traumatic injury and sprain, promoting blood circulation, relieving swelling and pain, and eliminating scar.
In the prior art, there exists some technical means by applying aloe to eliminating scar. However, they are implemented by peeling the aloe and smearing it on the surface of the scar, which has the defects of narrow applicable field and poor scar eliminating effect. Therefore, it is necessary to study how to combine the aloe with a variety of medicines so as to allow the medical effects thereof to promote each other, and further achieve comprehensive scar eliminating effects.
SUMMARY OF THE INVENTION
To overcome the defects of narrow applicable field and poor scar eliminating effect for current aloe scar eliminating medicines, the present invention provides a Barbados aloe scar eliminating ointment having good comprehensive pharmaceutical property and good healthcare effect. The Chinese medicine according to the present invention is prepared by taking Barbados aloe as main raw material, and combines the effects of traditional medicinal materials and research achievements of modem pharmacology
For this purpose, the present invention discloses a Barbados aloe scar eliminating ointment, comprising, by weight parts, peeled Barbados aloe 25-30, dark plum 10-15, kuh-seng 2-5, centipede 2-4, peeled cactus 5-10, bomeol powder 1-6, Fritillaria 1-3, and pangolin 3-7.
According to one embodiment of the present invention, the Barbados aloe scar eliminating ointment comprises, by weight parts, peeled Barbados aloe 26, dark plum 10, kuh-seng 3, centipede 2, peeled cactus 6, bomeol powder 1, Fritillaria 1, and pangolin 4.
According to one embodiment of the present invention, the Barbados aloe scar eliminating ointment comprises, by weight parts, peeled Barbados aloe 28, dark plum 12, kuh-seng 3, centipede 3, peeled cactus 8, bomeol powder 3, Fritillaria 1, and pangolin 5.
According to one embodiment of the present invention, the Barbados aloe scar eliminating ointment comprises, by weight parts, peeled Barbados aloe 29, dark nlnm 14 knh-senn 4 rentinede ^ npplpH riirtiis O hnmml nnwHpr S Fritillnriii 9 and pangolin 6.
According to one embodiment of the present invention, the Barbados aloe scar eliminating ointment further comprises, by weight parts, musk 2-5 and leech 4-6.
The preparation method and administration method of above Barbados aloe scar eliminating ointment are as follows: weighing all of the raw materials according to their weight parts, mixing and grinding the same to obtain a paste; adding 450ml of water into lOOg of the paste, decocting the same for concentration to obtain a pasty ointment; and after cooling, smearing above ointment at the scar, wherein the ointment is replaced once for every day, and three times of administration constitute a course period of treatment.
The raw materials applied in the Barbados aloe scar eliminating ointment have the pharmacological performances as follows:
Barbados aloe: (Scientific name: Aloe vera) is a perennial evergreen herbaceous plant in Liliaceae of Aloe, its leaves are fascicular, big and fleshy, in seat shape or at the stem top, typically lanceolar or short and wide, and with sharp teeth-like spines on the edges thereof. Barbados aloe’s inflorescence is umbel, raceme, spica, or cone-shaped; it has red or yellow color or has red spots thereon, and has six petals and six pistils. Its perianth base parts are combined to have a barrel shape. It is native to Mediterranean and Africa, and is popular as a mottle-leaf ornamental plant for being easily cultivated. In China folklore, the aloe is used as a natural medicine for cosmetology, hair care, and treatment of skin diseases. The peeled aloe refers to aloe with epidermis being removed.
Dark plum: traditional Chinese medicine name, is a dried matured fruit of Rosaceae plant-Prunus mume(Sieb.)Sieb.etZuce . It is cultivated in various regions of China, and mostly distributed in the provinces in south of the Yangtze river basin. It has the effects in astringing lung, astringing intestine, promoting the secretion of body fluid, and relieving colic caused by ascaris, and is usually used for alleviation of lung deficiency and chronic cough, chronic diarrhea and lingering dysentery, asthenic fever and diabetes, emesis and abdominal pain caused by ascariasis of biliary tract.
Kuh-seng: traditional Chinese medicine, is a dried root of Leguminosae plant-radix sophorae flavescentis. It is harvested in spring and autumn, root apex and small rootlets thereof are removed, and then dried or fresh-sliced followed by drying. It has the effects of heat clearing and damp drying, disinfestation, and diuresis; and is used for the treatment of dysentery, hemafecia, jaundice/anuresis, leukorrhea with reddish discharge, swelling and pruritus of vulvae, eczema, eczema, skin itch, scabies/leprosy, and trichomonas vaginitis.
Centipede: is a terrestrial arthropod, its long body is composed of many somites each having walking legs grown thereon, and thus it is a multi-legged creature. It has many aliases, has poison gland and is predatory. Common centipedes are classified into red head type, blue head type and black head type. The red head type of centipede has reddish black back, pale red abdomen, and pale jacinth or yellow leg. The blue head type of centipede has blue back and leg, pale blue abdomen, small size, and a length approximately half the length of the red head type of centipede. It has poison gland for secreting venom, and can be used as medicine. It is suitable for artificial feeding. It’s features are recorded in "Compendium of Materia Medica" and "Ben Cao Yan Yi". The centipede together with snake, scorpion, gecko and toad are called "The Five Venoms", and the centipede is ranked first in the top five.
Cactus: scientific name: Opuntia stricta (Haw.) Haw. var. dillenii (Ker-Gawl.) Benson, is a plant in Cactaceae of Opuntia, and has many aliases. It is a clustered meaty shrub, and has: obovate, obovate-shaped oval or nearly round upper branch; rotate inflorescence, obovate receptacle; and flat round (mostly) seed (slightly irregular edge, no hair, pale brown). It is fond of strong sunlight, and is resistant to torridity, drought and barren; it has tenacious vitality, and suitable growth temperature of 20-30 °C. Peeled cactus refers to a remainder obtained by removing the epidermis of the cactus, and the barb and villus located on the epidermis.
Bomeol: has many aliases, is obtained by steam-distilling stem and leaves of Blumea balsamifera in Asteraceae or Cinnamomum camphora in Lauraceae followed by recrystallization. It can also be obtained by treating turpentine with a series of chemical methods. It can be used for the treatment of blockage syndrome and coma, hot eyes and sore pain, pharyngitis and aphtha, ulcer and sore pain, and so on. It is poisonous and should be used with caution.
Fritillaria: it is recorded in Chinese document “BEN CAO ZHENG”.
Pangolin: its scale and shell are used as medicine, and has the effect in invigorating the circulation of blood and eliminating carbuncle; and is mainly used for treatment of blood stasis and amenorrhea, abdominal mass, rheumatism, carbuncle swelling; and struma.
Musk: is a secreta for gonad of male musk deer living in plateau of the northwest and southwest of China, and cold zones in Nepal and Siberia. Two-year-old male musk deer begins to secreting musk, about 10-year-old male musk deer is in a best secretory phase, and each musk deer can secrete about 50g. In addition, other animals such as desman also have similar musk secretion. The musk shows granular or block shape after drying, has special aroma, bitter taste, can be made into perfume, and can also be used as medicine. It is a nervous centralis stimulant, has the effects of analgesia and detumescence, and is very precious. Musk has blood-breaking and stasis effects, and is inedible for pregnant woman.
The Barbados aloe scar eliminating ointment provided in the present invention has the effect in eliminating scar, and has special effects for traumatic scar, pimple scar and hyperplastic scar.
Other features and advantages of the present invention will be described in detail in the following specific embodiments.
DETAILED DESCRIPTION OF THE EMBODIMENTS
The present invention provides multiple applicable creative concepts, which are embodied in the specific context. The specific examples described in the embodiments of the present invention only serve as the exemplary illustration for the specific implementation manners, but are not meant limiting the present invention.
Without loss of generality, the present invention discloses a Barbados aloe scar eliminating ointment, comprising by weight parts, peeled Barbados aloe 25-30, dark plum 10-15, kuh-seng 2-5, centipede 2-4, peeled cactus 5-10, bomeol powder 1-6, Fritillaria 1-3, and pangolin 3-7.
Wherein, all the above raw materials can be commercially available finished products, and also can be obtained with common preparation method, for example, can be prepared by drying and pulverizing crude materials into commonly-used powder in the art. The drying method can be baking or naturally drying, and preferably naturally drying. The pulverizing method can be a commonly-used method in the field of traditional Chinese medicine.
The Barbados aloe scar eliminating ointment provided in the present invention can eliminate scar without trace left, to thereby allow the skin to be fine and smooth.
In order to further implement above technical solution, the present invention provides a preparation method and administration method of above Barbados aloe scar eliminating ointment as follows: weighing all of the raw materials according to their weight parts, mixing and grinding the same to obtain a paste; adding 450ml of water into 100 g of the paste, decocting the same for concentration to obtain a pasty ointment; and after cooling, smearing above ointment at the scar, wherein the ointment is replaced once for every day, and three times of administration constitute a course period of treatment.
Below, the present invention will be described in more detail through the examples.
Examples 1-5
Examples 1-5 are used to illustrate the Barbados aloe scar eliminating ointment provided in the present invention.
According to the weight parts listed in Table 1, Barbados aloe scar eliminating ointments 1-5 are obtained.
Table 1
Experimental examples 1-5
Experimental examples 1-5 are used to illustrate the scar eliminating effects of the Barbados aloe scar eliminating ointment provided in the present invention. (1) The scar eliminating effect for traumatic scar 150 male and female patients (in the age range of 25-70) with the traumatic scar at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Barbados aloe scar eliminating ointments 1-5 are used in the five groups, respectively. For administration, the Barbados aloe scar eliminating ointment is smeared at the positions with scar (replaced once a day, a treatment course of 3 times), and after 12 days, the effects are observed. Compared with a condition before administration, the patient whose scar completely disappears is marked as o, the patient whose scar is remarkably alleviated is marked as Δ, and the patient whose scar has no remarkable alleviation is marked as x, and the scar eliminating effects are shown in Table 2.
Table 2
(2) The scar eliminating effect for pimple scar 150 male and female patients (in the age range of 35-60) with the pimple scar at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Barbados aloe scar eliminating ointments 1-5 are used in the five groups, respectively. For administration, the Barbados aloe scar eliminating ointment is smeared at the positions with scar (replaced once a day, a treatment course of 3 times), and after 12 days, the effects are observed. Compared with a condition before administration, the patient whose scar completely disappears is marked as o, the patient whose scar is remarkably alleviated is marked as A, and the patient whose scar has no remarkable alleviation is marked as x, and the scar eliminating effects are shown in Table 3.
Table 3
(3) The scar eliminating effect for hyperplastic scar 150 male and female patients (in the age range of 55-70) with the hyperplastic scar at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Barbados aloe scar eliminating ointments 1-5 are used in the five groups, respectively. For administration, the Barbados aloe scar eliminating ointment is smeared at the positions with scar (replaced once a day, a treatment course of 3 times), and after 12 days, the effects are observed. Compared with a condition before administration, the patient whose scar completely disappears is marked as o, the patient whose scar is remarkably alleviated is marked as Δ, and the patient whose scar has no remarkable alleviation is marked as x, and the scar eliminating effects are shown in Table 4.
Table 4
It can be seen from the experimental results that: the Barbados aloe scar eliminating ointment provided in the present invention can effectively eliminate traumatic scar, pimple scar and hyperplastic scar without trace left.
It should be noted that the above examples are used for illustrating, but not meant to limit the present invention. And those skilled in the art can design alternative examples without departing from the scope of the appended claims. In the Claims, the reference marks between brackets should not be construed to limit the Claims. The word “comprising” does not exclude the presence of other elements or steps which are not listed in the Claims.

Claims (6)

1. A Barbados aloe scar eliminating ointment, comprising by weight parts, peeled Barbados aloe 25-30, dark plum 10-15, kuh-seng 2-5, centipede 2-4, peeled cactus 5-10, bomeol powder 1-6, Fritillaria 1-3, and pangolin 3-7.
2. The Barbados aloe scar eliminating ointment according to claim 1, comprising by weight parts, peeled Barbados aloe 26, dark plum 10, kuh-seng 3, centipede 2, peeled cactus 6, bomeol powder 1, Fritillaria 1, and pangolin 4.
3. The Barbados aloe scar eliminating ointment according to claim 1, comprising by weight parts, peeled Barbados aloe 28, dark plum 12, kuh-seng 3, centipede 3, peeled cactus 8, bomeol powder 3, Fritillaria 1, and pangolin 5.
4. The Barbados aloe scar eliminating ointment according to claim 1, comprising by weight parts, peeled Barbados aloe 29, dark plum 14, kuh-seng 4, centipede 3, peeled cactus 9, bomeol powder 5, Fritillaria 2, and pangolin 6.
5.
The Barbados aloe scar eliminating ointment according to any one of claims 1-4, further comprising by weight parts, musk 2-5 and leech 4-6.
DKPA201670336A 2015-11-02 2016-05-20 A Barbados aloe scar eliminating ointment DK201670336A1 (en)

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CN109381357B (en) * 2018-12-13 2021-09-03 广州宝莱生物科技有限公司 Leech freeze-dried powder capable of removing acne and moisturizing skin

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