CN109069754B - 准确、精确的微升剂量注射器 - Google Patents

准确、精确的微升剂量注射器 Download PDF

Info

Publication number
CN109069754B
CN109069754B CN201780023860.9A CN201780023860A CN109069754B CN 109069754 B CN109069754 B CN 109069754B CN 201780023860 A CN201780023860 A CN 201780023860A CN 109069754 B CN109069754 B CN 109069754B
Authority
CN
China
Prior art keywords
plunger rod
rod assembly
syringe
assembly
gear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780023860.9A
Other languages
English (en)
Chinese (zh)
Other versions
CN109069754A (zh
Inventor
G·N·谢蒂
L·卡斯塔纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Congruence Medical Solutions LLC
Original Assignee
Santen Pharmaceutical Co Ltd
Congruence Medical Solutions LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd, Congruence Medical Solutions LLC filed Critical Santen Pharmaceutical Co Ltd
Publication of CN109069754A publication Critical patent/CN109069754A/zh
Application granted granted Critical
Publication of CN109069754B publication Critical patent/CN109069754B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201780023860.9A 2016-04-15 2017-04-07 准确、精确的微升剂量注射器 Active CN109069754B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662323341P 2016-04-15 2016-04-15
US62/323,341 2016-04-15
PCT/US2017/026684 WO2017180480A1 (en) 2016-04-15 2017-04-07 Accurate, precise microliter dosing syringe

Publications (2)

Publication Number Publication Date
CN109069754A CN109069754A (zh) 2018-12-21
CN109069754B true CN109069754B (zh) 2021-09-07

Family

ID=60041890

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780023860.9A Active CN109069754B (zh) 2016-04-15 2017-04-07 准确、精确的微升剂量注射器

Country Status (10)

Country Link
US (2) US11707577B2 (https=)
EP (2) EP3442623B1 (https=)
JP (1) JP7076106B2 (https=)
KR (1) KR102385255B1 (https=)
CN (1) CN109069754B (https=)
ES (1) ES2860801T3 (https=)
PT (1) PT3442623T (https=)
RU (1) RU2738018C2 (https=)
TW (1) TWI755388B (https=)
WO (1) WO2017180480A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7076106B2 (ja) 2016-04-15 2022-05-27 参天製薬株式会社 正確で優れた精度のマイクロリットル投薬シリンジ
JP7098171B2 (ja) 2017-06-16 2022-07-11 クリーデンス メドシステムズ，インコーポレイテッド 安全シリンジのシステムおよび方法
FR3072297B1 (fr) * 2017-10-17 2023-05-12 Edix Sa Dispositif d'injection manuelle
CN117138171A (zh) 2017-12-13 2023-12-01 里珍纳龙药品有限公司 用于精确剂量输送的装置和方法
EP3856295B1 (en) * 2018-09-26 2023-03-08 Galderma S.A. Injection device
CN117159272A (zh) * 2018-10-24 2023-12-05 新世界医学有限公司 眼科装置和用于该眼科装置的内部机构
US10722397B2 (en) 2018-10-24 2020-07-28 New World Medical, Inc. Ophthalmic device
CA3239521A1 (en) 2018-11-13 2020-05-22 Credence Medsystems, Inc. System and method for multiple site injection
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
GB2584730B (en) * 2019-06-14 2022-04-13 Owen Mumford Ltd Drug delivery device assembly
JP7779833B2 (ja) * 2019-11-14 2025-12-03 コングルーエンス メディカル ソリューションズ，エルエルシー 可変投薬注射器
CA3165419A1 (en) * 2020-01-27 2021-08-05 John Picot Rotating luer connector
EP4168067B1 (en) 2020-06-17 2025-08-27 Credence Medsystems, Inc. System and method for microdose injection
EP4221789A1 (en) * 2020-09-30 2023-08-09 Becton Dickinson France A dose setting assembly for a medical injection device
US20230285680A1 (en) * 2022-03-11 2023-09-14 Altek Biotechnology Corporation Driving mechanism for driving a plunger of an auto-injector to slide relative to a reservoir of the auto-injector and auto-injector therewith
WO2023183937A1 (en) 2022-03-25 2023-09-28 Illumina, Inc. Sequence-to-sequence base calling
WO2023224584A1 (en) * 2022-05-18 2023-11-23 Bi̇med Tekni̇k Aletler Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ The adjustable-dosage syringe
JP2025533306A (ja) * 2022-10-17 2025-10-03 コングルーエンス メディカル ソリューションズ，エルエルシー 注入可能な薬の正確な送達のための薬剤送達デバイスおよび方法
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
KR20250139054A (ko) * 2024-03-14 2025-09-23 대구한의대학교산학협력단 피스톤 자동구동 타입 주사기
WO2026035797A1 (en) * 2024-08-09 2026-02-12 Credence Medsystems, Inc. System and method for multiple site dispensing or injection

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0800798A1 (de) * 1996-04-10 1997-10-15 Ernst Mühlbauer Kg Applikationsgerät für Dentalmasse
WO2008101829A1 (en) * 2007-02-20 2008-08-28 Novo Nordisk A/S An injection device comprising a worm gear connection
US7678084B2 (en) * 2002-03-18 2010-03-16 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3122280A (en) 1961-08-14 1964-02-25 Clay Adams Inc Adjustable stroke liquid dispenser having yieldable aligning means
US3770026A (en) 1971-09-17 1973-11-06 J Isenberg Apparatus and method for accurately loading syringes
US3964481A (en) 1972-04-28 1976-06-22 Albert Joseph Gourlandt Automatic injection device
US4073321A (en) 1976-03-15 1978-02-14 George Moskowitz Adjustable blocking means for dosage regulation
US4244366A (en) 1979-10-30 1981-01-13 Burron Medical, Inc. Syringe stroke controlling mechanism
GB2109690B (en) 1981-02-12 1985-02-20 Robert Charles Turner Dose metering plunger devices for use with syringes
US4563178A (en) 1985-02-06 1986-01-07 Santeramo Joseph J Syringe dosage limiter
GB8809115D0 (en) 1988-04-18 1988-05-18 Turner R C Syringes
US4921487A (en) 1988-09-21 1990-05-01 Compagnie Financiere Saint. Nicolas External device for injecting medicine
US4929238A (en) 1988-11-23 1990-05-29 Coeur Laboratories, Inc. Multi-pressure injector device
US5383858B1 (en) * 1992-08-17 1996-10-29 Medrad Inc Front-loading medical injector and syringe for use therewith
US5318544A (en) 1992-10-20 1994-06-07 Kerr Manufacturing Company Metering syringe
JPH09225031A (ja) 1996-02-28 1997-09-02 Terumo Corp 定量分与器
US5951526A (en) 1997-09-24 1999-09-14 Korisch; Marina Syringe holder with integral dose divider
US6562007B1 (en) 2000-09-28 2003-05-13 Bayer Healthcare Llc Adjustable dosage syringe
US7329241B2 (en) 2003-02-14 2008-02-12 Valeant Pharmaceuticals North America Drug delivery system for administering an adjustable preset dose
US20050215957A1 (en) 2004-03-26 2005-09-29 Mallinckrodt Inc. Calibrated pushrod for injection volume control in prefilled syringes
US20060217670A1 (en) * 2005-03-28 2006-09-28 Genx International, Inc. Assembly for aspiration and/or dispensing of organisms and fluids
US20070073224A1 (en) 2005-07-14 2007-03-29 John Dries Syringe with latching safety mechanism
DE102006040182A1 (de) 2006-08-26 2008-03-06 Mht Mold & Hotrunner Technology Ag Verfahren zur Herstellung eines mehrschichtigen Vorformlings sowie Düse hierfür
US7678094B1 (en) 2006-10-18 2010-03-16 Cannon Becky B Reusable swim diaper
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
TWI332851B (en) 2007-04-27 2010-11-11 Dermato Plastica Beauty Dpb Co Ltd Volume adjustable, micro-injection device
DK2237818T3 (en) 2008-01-28 2017-01-16 Shl Group Ab INJECTOR WITH thumb thumb operated wheel
US7976510B2 (en) * 2008-02-28 2011-07-12 Becton, Dickinson And Company Syringe with adjustable two piece plunger rod
US8312785B2 (en) 2008-06-20 2012-11-20 Graco Minnesota Inc. Involute gear teeth for fluid metering device
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
ES2625488T3 (es) 2008-09-18 2017-07-19 Becton, Dickinson And Company Inyector médico con activación de botón de dosis para reconstitución automática
CN102202710B (zh) 2008-09-18 2013-08-21 贝克顿·迪金森公司 具有可旋转主体部的医用注射器
CA2742810C (en) 2008-11-07 2016-11-29 Min Wei Injection pen for intradermal medication injection
NO2373362T3 (https=) 2008-12-04 2018-03-10
DK2414011T3 (da) * 2009-04-01 2016-05-09 Shl Group Ab Medikamentafgivelsesindretning
ES2749395T3 (es) 2009-11-20 2020-03-20 Becton Dickinson Co Dispositivo de inyección sin necesidad de un engranaje
WO2011088894A1 (de) 2010-01-20 2011-07-28 Tecpharma Licensing Ag Modulares verabreichungssystem für ein flüssiges medikament
CN101829381B (zh) 2010-04-07 2015-04-29 邓源基 一次性可调计量胰岛素注射笔
US9095657B2 (en) 2010-04-19 2015-08-04 Shl Group Ab Self-administration medicament delivery device
WO2012072554A1 (en) 2010-11-29 2012-06-07 Sanofi-Aventis Deutschland Gmbh Drug delivery device
US8535277B2 (en) 2011-03-21 2013-09-17 William Marsh Rice University Method and apparatus for dose measurement
CA2839493C (en) 2011-06-17 2016-02-09 Shl Group Ab Injection device
JP6298946B2 (ja) 2011-12-08 2018-03-28 ユーエヌエル ホールディングス エルエルシーＵＮＬ Ｈｏｌｄｉｎｇｓ ＬＬＣ 正確な投与制御機構及び薬物送達用注射器
US10328211B2 (en) 2011-12-08 2019-06-25 Unl Holdings Llc Automatic self-dispensing accurate dose drug delivery syringes
US9358343B2 (en) 2012-04-17 2016-06-07 Carebay Europe Ltd Medicament delivery device
DE202013000688U1 (de) 2012-07-03 2013-03-05 Novartis Ag Glas-Spritze
HK1214986A1 (zh) 2013-04-10 2016-08-12 Sanofi 注射装置
EP2801335B1 (de) 2013-05-07 2018-03-14 Ivoclar Vivadent AG Spritze
HK1220648A1 (zh) * 2013-07-17 2017-05-12 Sanofi 驱动机构
PL3054856T3 (pl) 2013-10-13 2021-06-14 V.V.T. Med Ltd. Urządzenie do zsynchronizowanego wstrzykiwania i zasysania
US10987471B2 (en) 2015-05-21 2021-04-27 Eli Lilly And Company Injection device drive with two gear patterns
GB2541227A (en) 2015-08-13 2017-02-15 Owen Mumford Ltd Injector Device
US20170258633A1 (en) 2016-03-14 2017-09-14 Virchow Biotech Pvt. Ltd. Novel device for ophthalmic delivery
JP7076106B2 (ja) 2016-04-15 2022-05-27 参天製薬株式会社 正確で優れた精度のマイクロリットル投薬シリンジ
US20180056009A1 (en) 2016-09-01 2018-03-01 Medimop Medical Projects Ltd. Injector with variable dosage
WO2018085768A2 (en) 2016-11-04 2018-05-11 Shire Small unit dosage plunger rod stops
CN206463986U (zh) 2016-12-01 2017-09-05 张卿义 一种易调式移液枪
CN206687978U (zh) 2016-12-22 2017-12-01 郑州万辉医疗设备有限公司 一种智能控制的电子笔式胰岛素注射器
CN106581822A (zh) 2016-12-22 2017-04-26 郑州万辉医疗设备有限公司 一种智能控制的电子笔式胰岛素注射器
EP3576819B1 (en) 2017-02-03 2023-08-16 Norton Healthcare Limited Assembly for a medication delivery device and medication delivery device
US11376367B2 (en) 2017-02-03 2022-07-05 Norton Healthcare Limited Assembly for a medication delivery device and medication delivery device
CN109966592A (zh) 2017-02-04 2019-07-05 王才丰 一种可自主取药的大剂量无针注射器
GB2559553B (en) 2017-02-06 2021-10-13 Consort Medical Plc A medicament delivery device
CN107866287A (zh) 2017-12-26 2018-04-03 李彩华 一种医学检验用移液管装置
CN109999936B (zh) 2019-04-27 2020-09-15 苏桥生物(苏州)有限公司 应用于生物/化工/医药试验、检测的高精度定量移液枪
KR20190127620A (ko) 2019-10-26 2019-11-13 김도경 소 예방주사용 장대형 주사기
JP7779833B2 (ja) 2019-11-14 2025-12-03 コングルーエンス メディカル ソリューションズ，エルエルシー 可変投薬注射器

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0800798A1 (de) * 1996-04-10 1997-10-15 Ernst Mühlbauer Kg Applikationsgerät für Dentalmasse
US7678084B2 (en) * 2002-03-18 2010-03-16 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
WO2008101829A1 (en) * 2007-02-20 2008-08-28 Novo Nordisk A/S An injection device comprising a worm gear connection

Also Published As

Publication number Publication date
US20210178080A1 (en) 2021-06-17
KR20180134937A (ko) 2018-12-19
KR102385255B1 (ko) 2022-04-08
ES2860801T3 (es) 2021-10-05
WO2017180480A8 (en) 2018-09-13
PT3442623T (pt) 2021-02-17
US20230355885A1 (en) 2023-11-09
EP3442623A4 (en) 2019-10-23
TW201801761A (zh) 2018-01-16
US12611509B2 (en) 2026-04-28
RU2018139650A (ru) 2020-05-15
CA3018880A1 (en) 2017-10-19
JP7076106B2 (ja) 2022-05-27
RU2738018C2 (ru) 2020-12-07
RU2018139650A3 (https=) 2020-07-24
US11707577B2 (en) 2023-07-25
JP2019511350A (ja) 2019-04-25
EP3834868A1 (en) 2021-06-16
WO2017180480A1 (en) 2017-10-19
EP3442623A1 (en) 2019-02-20
TWI755388B (zh) 2022-02-21
EP3442623B1 (en) 2021-01-20
CN109069754A (zh) 2018-12-21

Similar Documents

Publication Publication Date Title
CN109069754B (zh) 准确、精确的微升剂量注射器
US7090662B2 (en) Dose dial and drive mechanisms suitable for use in drug delivery devices
EP2774637B1 (en) Cartridge interface assembly
JP5080976B2 (ja) 薬剤デリバリ装置の組み立て方法
KR20140105457A (ko) 정확한 투여량 제어 메커니즘 및 약물 전달 주사기
CN102238973B (zh) 适于在药物递送装置中使用的驱动组件及药物递送装置
CN102083487A (zh) 药物输送设备
AU2007207309A1 (en) Injection device with secured dosing button
AU2007207310A1 (en) Pusher with a coupling element
US20240374824A1 (en) Medical delivery device
HK40000259A (en) Accurate, precise microliter dosing syringe
CA3018880C (en) Accurate, precise microliter dosing syringe
HK40000259B (zh) 准确、精确的微升剂量注射器
HK40000032B (en) Accurate, precise microliter dosing syringe
HK40000032A (en) Accurate, precise microliter dosing syringe
JP2022551163A (ja) 薬剤送達装置のためのキー付きコネクタ
AU2004222587B2 (en) Dose dial and drive mechanism suitable for use in drug delivery devices
HK1092084B (en) Improvements in and relating to drive mechanisms suitable for use in drug delivery devices
HK1092084A1 (zh) 适用於给药装置的驱动机构中的改进以及相关改进

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40000259

Country of ref document: HK

GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20250421

Address after: American Maryland

Patentee after: CONGRUENCE MEDICAL SOLUTIONS LLC

Country or region after: U.S.A.

Address before: Osaka, Japan

Patentee before: SANTEN PHARMACEUTICAL Co.,Ltd.

Country or region before: Japan

Patentee before: CONGRUENCE MEDICAL SOLUTIONS LLC

Country or region before: U.S.A.