US3122280A - Adjustable stroke liquid dispenser having yieldable aligning means - Google Patents

Adjustable stroke liquid dispenser having yieldable aligning means Download PDF

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US3122280A
US3122280A US131317A US13131761A US3122280A US 3122280 A US3122280 A US 3122280A US 131317 A US131317 A US 131317A US 13131761 A US13131761 A US 13131761A US 3122280 A US3122280 A US 3122280A
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piston
barrel
guide
movable
movement
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US131317A
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Goda George
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Clay-Adams Inc
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Clay-Adams Inc
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/06Test-tube stands; Test-tube holders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31555Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31591Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0282Burettes; Pipettes mounted within a receptacle

Description

Feb. 25, 1964 3,122,280

G. GODA ADJUSTABLE STROKE LIQUID DISPENSER HAVING YIELDABLE ALIGNING MEANS Filed Aug. 14, 1961 llllllllllllllllmll EEIIIIIIIIIIIIIIIHIIII !lI|ll-" [I a H FIG.2 m W1 FIG! INVENTOR. GEORGE GO DA BY @w 87. MM

United States Patent 3522,2859 ADJUSTABLE g'i'itfiihl LIQUID DISPENfiER IAVEYG YELDAELE ALEQNENG MEANS George Soda, New York, N.Y., assignor to Clay-Adams, ind, New York, NY a corporation of New York Filed Aug. 14, 1961, Ser. No. 131,317 9 laims. (Cl. 2223tl9) This invention relates to liquid dispensers and more particularly concerns pipettes or the like for dispensing a precise, predetermined quantity of liquid repeatedly therefrom.

Liquid dispensers of the pipette type, which comprise a barrel-piston syringe and associated attachments for limiting the travel of the piston in the barrel, have been proposed. The user of such a device presses the piston downwardly in the barrel by applying the thumb to the head of the piston. If the thumb or point of pressure is slightly ofi center with respect to the axis of the piston, the downstroke of the piston may result in a binding action as between the piston and the barrel, causing poor reciprocatory action in the device.

Also, in the case of the smaller capacity syringes of the order of l and 3 cc., the pistons are of very small diameter which renders them susceptible to breakage when the piston is depressed with even a slightly on center application of pressure to the piston head.

Accordingly, an object of this invention is to provide a barrel-piston syringe with means for interconnecting the relatively movable parts of the syringe to positively guide the movement of the piston relative to the barrel irrespective of the point of application of pressure for the downstroke of the piston.

Another object of this invention is to provide positive guide means for the piston of a barrel-piston syringe, such guide means also including presettable means for limiting the travel of the piston in the barrel so as to dispense precise equal quantities of liquid each time the piston is reciprocated.

A further object of this invention is to provide an improved piston guide and stop means for a syringe wherein the stop means may be adjusted to vary the extent of travel of the piston in the barrel, together with Vernier adjustment means for making fine precise adjustments of the position of the stop means to thereby finely adjust the quantity of liquid dispensed.

Other objects of this invention will in part be obvious and in part hereinafter pointed out.

In the drawing, FIG. 1 is a side elevational view of a liquid dispensing device embodying the invention;

FIG. 2 is a vertical view thereof with parts in section; and

FIG. 3 is a transverse sectional view taken on the line 3-3 of FIG. 2.

Referring in detail to the drawing, designates a liquid dispenser of the barrel-piston type, embodying the invention. The same comprises a conventional tubular glass syringe barrel 11 having a dispensing tip 12 at the lower end thereof and the usual radial flange 13 at the upper open end thereof. A glass piston 14 is reciprocably mounted in barrel l1 and is ground to have a fine precision sliding fit with the inner barrel surface. Piston 14 has the usual neck portion 15 and terminates at its head in a radial flange 16 which has a diameter somewhat greater than the diameter of the piston proper.

Combination guide and stop means, generally indicated at 1'7, interconnects barrel 11 and piston l d to adjustably set the travel of piston 14 in barrel 11, whereby to accurately detemiine the quantity of liquid drawn up into the barrel 11 on the upstroke of piston 14, which quantity is dispensed on the downstroke of said piston.

Means 17 comprises a barrel attachment including a 3,i22,28 Patented Feb. 25, 1984 cupped member 18 having a bottom wall 19 formed with a central opening 19A for passing the barrel 11; the barrel flange l3 resting on the top surface of wall 19. The cylindrical side wall 2% of member 18 is internally threaded to receive an externally threaded cup shaped member 21 which has a bottom wall 22 formed with a central opening 23 having a diameter which will pass the piston 14.

Flange 13 of barrel 11 is firmly clamped between Wall 19 of member 13 and wall 22 of member 21; a gasket 24 being interposed between barrel flange 13 and member 21. The cupped member 18 further includes a laterally related, vertically disposed internally threaded guide collar 25 which is integral with side wall 2% of member 18.

A tubular guide screw as is threaded into collar 25, said screw having an intermediate threaded portion 27, a knurled, radial head portion 28 at the upper end thereof, a neck portion 29 between portions 27 and 28, and a lower end portion 39 of slightly reduced diameter.

Means 1'7 further includes a guide attachment mounted on the upper head end of piston 14. Such attachment includes a cup shaped member 31 with a bottom wall 32 formed with a central opening 33 which will pass the piston proper but seats piston flange 16 on Wall 32. The cylindrical side wall 34 of member 31 is internally threaded, the side wall terminating at its upper end in a radial flange 35.

The piston flange 16 is resiliently held against wall 32 by a screw 36 threaded into member 31. Screw 36 is formed with an axial recess 37 to receive a spring 38 therein. The lower end of spring 38 bears against the top surface 39 of piston flange t5, the bottom edge of the screw being short thereof. The bias of spring 38 is regulated by turning screw 36 in one direction or the other. Thus, while the piston 14 may be firmly held in attachment member 31, the connection therebetween is of a complaint or floating type.

Members 18 and 31 are interconnected by a guide pin 45? which extends in parallel relation to the longitudinal axes of barrel 11 and piston 14. The pin 4t} is connected to member 31 by a retainer ring 41 which is force fitted on said member 31 and abuts the underside of flange thereof. Ring 41 includes a laterally oifset portion 42 which is formed with an opening 43, in which is force fitted the upper reduced end portion 44 of guide pin 41.

The lower end portion 45A of pin 43 passes through the axial bore 45 of screw 26 with a slide fit therein, and a stop ring 45 is adjustably mounted on pin portion A by a set screw 47. As the stop ring 46 abuts the lower end of screw portion 39, the extent of the outward movement of piston 14 relative to barrel 11 is limited; piston 14 being biased outwardly of the barrel by the usual coil spring 4-8 extending about the upper portion of piston 1 abutting ring 41 at its upper end and wall 22 of member 21 at its lower end.

It will be apparent that stop ring 46 may be fixed in selected aositic-ns along pin as to give a reasonably precise setting of the same on said guide pin. However, the setting may be made even more precise by rotating screw 26 in one direction or the other to shift the position of abutment portion 3% of said screw over extremely small longitudinal increments. A coil spring 49 about neck portion 29 of screw as, which abuts the collar 25 at its lower end, keeps screw 26 from turning in collar 25 as an incident to vibration of the device; thus preserving a Vernier setting of screw 26.

Member 18 includes the usual finger holding grips 5i) which project radially and diametrally from wall 20 thereof. A conventional Luer lock 12A may be mounted on barrel tip 12 for suitable connection.

As guide pin 4i"; has a smooth sliding fit in bore of screw 25 and is fixedly attached to member 31 by way of ring 41; the movement of piston 14 in barrel 11 is positively guided, irrespective of the precise point of application of pressure to the head of screw 36 for depressing the piston 34. However, the piston flange is in floating relation to member 31 rather than in a rigid, fixed relation thereto; thereby all wing piston 14 to accommodate itself to barrel 11 during the reciprocatory movements of the piston 14 incident to the filling and discharge of device 1-9.

When device id is used repeatedly at successive intervals to dispense a substantial number of equal quantities of liquid, t. e pressure applied each time piston 14 is depressed may vary and thereby possibly aliect the extent of travel of the piston, with a possibility of insui icient depression of the piston, in some cases. However, with the floating relation of piston 14 relative to member 31, the u er may regularly exert pressures somewhat in excess of that necessary to fully de ress the piston, thus insure full depressed travel of the piston at all times.

Furthermore, spring 3?: is effective to absorb any shock if the bottom of piston 14 makes sudden contact with the lower end of barrel ll upon depressed movement of said piston, thus avoiding possible breakage of the syringe parts.

As various changes might be made in the embodiment of the invention herein disclosed, without departing from the spirit thereof, it is understood that all matter herein shown or described shall be deemed illustrative and not limiting except as set forth in the appended claims.

Having thus disclosed my invention, 1 claim as new and d sire to protect by Letters Patent:

1. In combination with a liquid dispensing device having a cylindrical barrel open at one end thereof and a piston reciprocably mounted in the other end thereof, means for guiding the travel of the piston relative to said barrel upon depressing the head of said piston, said means comprising a first member fixedly mounted on said barrel, a second member yield-ably mounted on said piston, a guide member extending between said members with one end thereof fixedly secured to one of said members for concurrent movement therewith and means on the other of said members for slidably engaging the other end of said guide member to direct the movement thereof in a confined longitudinal path without lateral deviation therefrom, a stop member slidably mounted on said guide member with means for fixing said stop member in selected positions along said guide member for abutment with said other member upon movement of said piston outwardly of said barrel, spring means disposed to bias said piston outwardly of said barrel, and resilient means between opposed portions of said second member and said piston whereby said piston may accommodate itself to said barrel during the guided movement thereof relative to said barrel.

2. A device as in claim 1 and further including movable means on said first member engageable with said guide member for imparting finely adjusted longitudinal movements of said guide member relative to said first member in response to movement of said movable means.

3. A device as in claim 2 wherein said first member includes a threaded collar and said movable means comprises a tubular screw threaded into said collar with the lower end thereof abutting said stop member, said guide member passing through the bore of said tubular screw.

4. A device as in claim 3 wherein said second member comprises a cup shaped member for seating the upper end of said piston therein, and said resilient means comprises a nut threaded into said cup shaped member and a spring between said nut and the upper end of said piston, said nut being turnable to adjust the bias of said spring relative to the upper end of said piston.

5. A liquid dispenser comprising a barrel having a dispensing tip at one end thereof and open at the other end thereof, a piston reciprocably mounted in the open end of said barrel, means for guiding the movement of the piston relative to he barrel upon reciprocation thereof, said guiding eans comprising an elongated guide member extending parallel to the longitudinal axes of said barrel and p ton, means rigidly secured to said barrel and including me: is for slidably passing the lower end portion 1 guide member in a confined longitudinal path parall l to said axes of the barrel and piston, means interconnecting the upper end of said guide member with the upper end of said piston comprising an engaging member fixedly secured to said guide member, said engaging iding means for yieldably receiving an upper portion of said piston, spring means biasing the upper end portion of the piston relative to said engaging memher, and means for resiliently biasing said piston outwardly of said barrel.

6. A liquid dispenser comprising a barrel having a dispensing tip at one end thereof and being open at the other end thereof, a piston rcciprocably mounted in the open end of the barrel, means for resiliently biasing the piston outwardly of the barrel, means for guiding the movement of the piston relative to the barrel, said guiding comprising an elongated guide member disposed parallel to the longitudinal axes of the barrel and piston, a tubular member rigidly secured to said barrel, one end portion of said guide member slidably passing through said tubular member in a laterally confined predetermined longitudinal path, means for connecting the other end of said guide member to the head of said piston, said connecting means comprising a member for yieldably engaging the head of the piston for permitting relative movement therebetween, means for limiting the relative movement between said connecting means and said piston, and abutment means on the one end portion of said guide member engageable with said tubular member for limiting the outward movement of said piston relative to said barrel upon reciprocatory movement of said piston.

7. A liquid dispenser as in claim 6 wherein said connecting means comprises an internally threaded cupped member having a central opening for mounting the head of the piston therein, a screw member in said cupped member and spring means between said screw member and the head of said piston.

8. A liquid dispenser as in claim 6 wherein said tubular member is internally threaded and a tubular screw is threaded into said tubular member, said abutment means engaging one end of said tubular screw.

9. A liquid dispenser comprising a barrel having a dispensing tip at one end and being open at the other end, a piston reciprocably mounted in the open end of said barrel, means for resiliently biasing said piston outwardly of said barrel, guide means fixed on said barrel, dcpressible movable means slidably engaging said guide means for guided movement of said movable means in a determined longitudinal path and for depressing said piston within said barrel, said movable means comprising a portion in opposed relation to the head of said piston, yieldable means between the head of said piston and the opposed portion of said movable means for permitting limited continued depressed movement of said movable means after said piston has been depressed to a position bringing its lower end into abutment with the lower end of said barrel, and adjustable stop means on said movable means for engagement with said guide means for limiting the outward movement of said piston relative to said barrel.

References (Iited in the file of this patent UNITED STATES PATENTS FOREIGN PATENTS France Apr. 19,

Claims (1)

  1. 9. A LIQUID DISPENSER COMPRISING A BARREL HAVING A DISPENSING TIP AT ONE END AND BEING OPEN AT THE OTHER END, A PISTON RECIPROCABLY MOUNTED IN THE OPEN END OF SAID BARREL, MEANS FOR RESILIENTLY BIASING SAID PISTON OUTWARDLY OF SAID BARREL, GUIDE MEANS FIXED ON SAID BARREL, DEPRESSIBLE MOVABLE MEANS SLIDABLY ENGAGING SAID GUIDE MEANS FOR GUIDED MOVEMENT OF SAID MOVABLE MEANS IN A DETERMINED LONGITUDINAL PATH AND FOR DEPRESSING SAID PISTON WITHIN SAID BARREL, SAID MOVABLE MEANS COMPRISING A PORTION IN OPPOSED RELATION TO THE HEAD OF SAID PISTON, YIELDABLE MEANS BETWEEN THE HEAD OF SAID PISTON AND THE OPPOSED PORTION OF SAID MOVABLE MEANS FOR PERMITTING LIMITED CONTINUED DEPRESSED MOVEMENT OF SAID MOVABLE MEANS AFTER SAID PISTON HAS BEEN DEPRESSED TO A POSITION BRINGING ITS LOWER END INTO ABUTMENT WITH THE LOWER END OF SAID BARREL, AND ADJUSTABLE STOP MEANS ON SAID MOVABLE MEANS FOR ENGAGEMENT WITH SAID GUIDE MEANS FOR LIMITING THE OUTWARD MOVEMENT OF SAID PISTON RELATIVE TO SAID BARREL.
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Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211335A (en) * 1963-12-24 1965-10-12 Labindustries Liquid dispensing device
US3430813A (en) * 1967-04-17 1969-03-04 Cole Parmer Instr & Equipment Micrometric dispenser
US3516577A (en) * 1967-05-23 1970-06-23 Shandon Scient Ind Ltd Syringes
US3766784A (en) * 1971-06-16 1973-10-23 Sherwood Medical Ind Inc Pipettor stroke control mechanism
US3831602A (en) * 1972-02-11 1974-08-27 Union Plastics Corp Adjustable syringe assemblies
USRE28970E (en) * 1963-12-24 1976-09-21 Liquid dispensing device
US4098276A (en) * 1976-12-06 1978-07-04 American Hospital Supply Corporation Syringe pumping handle grip and method of assembling same
US4244366A (en) * 1979-10-30 1981-01-13 Burron Medical, Inc. Syringe stroke controlling mechanism
FR2464460A1 (en) * 1979-08-31 1981-03-06 Suovaniemi Finnpipette Pipette
US4442722A (en) * 1982-02-23 1984-04-17 Beckman Instruments Inc. Plunger operated pipet
US4518387A (en) * 1982-12-27 1985-05-21 Frank Murphy Syringe injection apparatus with adjustable dosage indicator
US4687472A (en) * 1986-11-12 1987-08-18 Gross Daniel A Injection assisting apparatus
US5033518A (en) * 1990-03-19 1991-07-23 National Instrument Company, Inc. Fine adjustment for filling machine having piston differential pressure
US5209731A (en) * 1991-12-13 1993-05-11 Endovascular Technologies, Inc. Hand-held gun for inflating and aspirating large volume balloons
US20140128841A1 (en) * 2012-11-02 2014-05-08 Cook Medical Technologies Llc Controlled Injection Devices, Systems, and Methods
US10166347B1 (en) 2014-07-18 2019-01-01 Patrick Vitello Closure assembly for a medical device
US10166343B1 (en) 2015-03-13 2019-01-01 Timothy Brandon Hunt Noise evident tamper cap
US10183129B1 (en) 2010-12-03 2019-01-22 Medical Device Engineering, Llc Tamper indicating closure assembly
US10207099B1 (en) 2014-02-21 2019-02-19 Patrick Vitello Closure assembly for medical fitting
US10300263B1 (en) 2015-02-27 2019-05-28 Timothy Brandon Hunt Closure assembly for a medical connector
US10307548B1 (en) 2016-12-14 2019-06-04 Timothy Brandon Hunt Tracking system and method for medical devices
US10315024B1 (en) 2015-03-19 2019-06-11 Patick Vitello Torque limiting closure assembly
US10758684B1 (en) 2017-03-03 2020-09-01 Jonathan J. Vitello Tamper evident assembly

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR52107E (en) * 1943-08-17
US2603389A (en) * 1952-07-15 Sirup dispensing unit fob soda
US2792157A (en) * 1955-10-07 1957-05-14 Clay Adams Inc Liquid dispensing device
US2823674A (en) * 1955-11-15 1958-02-18 Donald E Yochem Hypodermic syringe for veterinarians
US2916057A (en) * 1957-08-26 1959-12-08 Beckman Instruments Inc Fluid sampling device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR52107E (en) * 1943-08-17
US2603389A (en) * 1952-07-15 Sirup dispensing unit fob soda
US2792157A (en) * 1955-10-07 1957-05-14 Clay Adams Inc Liquid dispensing device
US2823674A (en) * 1955-11-15 1958-02-18 Donald E Yochem Hypodermic syringe for veterinarians
US2916057A (en) * 1957-08-26 1959-12-08 Beckman Instruments Inc Fluid sampling device

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211335A (en) * 1963-12-24 1965-10-12 Labindustries Liquid dispensing device
USRE28970E (en) * 1963-12-24 1976-09-21 Liquid dispensing device
US3430813A (en) * 1967-04-17 1969-03-04 Cole Parmer Instr & Equipment Micrometric dispenser
US3516577A (en) * 1967-05-23 1970-06-23 Shandon Scient Ind Ltd Syringes
US3766784A (en) * 1971-06-16 1973-10-23 Sherwood Medical Ind Inc Pipettor stroke control mechanism
US3831602A (en) * 1972-02-11 1974-08-27 Union Plastics Corp Adjustable syringe assemblies
US4098276A (en) * 1976-12-06 1978-07-04 American Hospital Supply Corporation Syringe pumping handle grip and method of assembling same
FR2464460A1 (en) * 1979-08-31 1981-03-06 Suovaniemi Finnpipette Pipette
US4244366A (en) * 1979-10-30 1981-01-13 Burron Medical, Inc. Syringe stroke controlling mechanism
US4442722A (en) * 1982-02-23 1984-04-17 Beckman Instruments Inc. Plunger operated pipet
US4518387A (en) * 1982-12-27 1985-05-21 Frank Murphy Syringe injection apparatus with adjustable dosage indicator
US4687472A (en) * 1986-11-12 1987-08-18 Gross Daniel A Injection assisting apparatus
US5033518A (en) * 1990-03-19 1991-07-23 National Instrument Company, Inc. Fine adjustment for filling machine having piston differential pressure
US5209731A (en) * 1991-12-13 1993-05-11 Endovascular Technologies, Inc. Hand-held gun for inflating and aspirating large volume balloons
US10183129B1 (en) 2010-12-03 2019-01-22 Medical Device Engineering, Llc Tamper indicating closure assembly
US20140128841A1 (en) * 2012-11-02 2014-05-08 Cook Medical Technologies Llc Controlled Injection Devices, Systems, and Methods
US10398844B2 (en) * 2012-11-02 2019-09-03 Cook Medical Technologies Llc Controlled injection devices, systems, and methods
US10207099B1 (en) 2014-02-21 2019-02-19 Patrick Vitello Closure assembly for medical fitting
US10166347B1 (en) 2014-07-18 2019-01-01 Patrick Vitello Closure assembly for a medical device
US10300263B1 (en) 2015-02-27 2019-05-28 Timothy Brandon Hunt Closure assembly for a medical connector
US10166343B1 (en) 2015-03-13 2019-01-01 Timothy Brandon Hunt Noise evident tamper cap
US10315024B1 (en) 2015-03-19 2019-06-11 Patick Vitello Torque limiting closure assembly
US10307548B1 (en) 2016-12-14 2019-06-04 Timothy Brandon Hunt Tracking system and method for medical devices
US10758684B1 (en) 2017-03-03 2020-09-01 Jonathan J. Vitello Tamper evident assembly

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