CN1089585C - 左布比卡因在面部手术中的用途 - Google Patents

左布比卡因在面部手术中的用途 Download PDF

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Publication number
CN1089585C
CN1089585C CN98802994A CN98802994A CN1089585C CN 1089585 C CN1089585 C CN 1089585C CN 98802994 A CN98802994 A CN 98802994A CN 98802994 A CN98802994 A CN 98802994A CN 1089585 C CN1089585 C CN 1089585C
Authority
CN
China
Prior art keywords
levobupivacaine
surgery
administered
bupivacaine
block
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN98802994A
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English (en)
Chinese (zh)
Other versions
CN1249684A (zh
Inventor
B·A·金纳利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of CN1249684A publication Critical patent/CN1249684A/zh
Application granted granted Critical
Publication of CN1089585C publication Critical patent/CN1089585C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN98802994A 1997-03-03 1998-03-03 左布比卡因在面部手术中的用途 Expired - Lifetime CN1089585C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9704352.5 1997-03-03
GBGB9704352.5A GB9704352D0 (en) 1997-03-03 1997-03-03 Levobupivacaine and its use

Publications (2)

Publication Number Publication Date
CN1249684A CN1249684A (zh) 2000-04-05
CN1089585C true CN1089585C (zh) 2002-08-28

Family

ID=10808603

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98802994A Expired - Lifetime CN1089585C (zh) 1997-03-03 1998-03-03 左布比卡因在面部手术中的用途

Country Status (20)

Country Link
US (1) US5919804A (https=)
EP (1) EP0981347B1 (https=)
JP (1) JP2001513812A (https=)
KR (1) KR100516676B1 (https=)
CN (1) CN1089585C (https=)
AT (1) ATE240730T1 (https=)
AU (1) AU730390B2 (https=)
BR (1) BR9808303A (https=)
CA (1) CA2279497C (https=)
DE (1) DE69814851T2 (https=)
DK (1) DK0981347T3 (https=)
ES (1) ES2199423T3 (https=)
GB (1) GB9704352D0 (https=)
HU (1) HU225151B1 (https=)
IL (1) IL131084A0 (https=)
NO (1) NO322446B1 (https=)
PL (1) PL190900B1 (https=)
PT (1) PT981347E (https=)
WO (1) WO1998038996A1 (https=)
ZA (1) ZA981779B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999004771A2 (en) * 1997-07-21 1999-02-04 Darwin Discovery Limited Use of levobupivacaine
WO1999004772A2 (en) * 1997-07-22 1999-02-04 Darwin Discovery Limited Use of levobupivacaine
AU752802C (en) 1997-11-14 2006-04-13 Pacira Pharmaceuticals, Inc. Production of multivesicular liposomes
IL140899A0 (en) 1998-07-17 2002-02-10 Skyepharma Inc Lipid/polymer containing pharmaceutical compositions and processes for the preparation thereof
AU2002322024B2 (en) * 2001-05-31 2008-05-08 Pacira Pharmaceuticals, Inc. Encapsulation of nanosuspensions in liposomes and microspheres
CN101327325A (zh) 2002-07-30 2008-12-24 奥默罗斯公司 眼科冲洗液及方法
DE10260313A1 (de) * 2002-12-20 2004-07-15 Siemens Ag Elektrische Maschine mit Wicklungen aus Litze
US20050176823A1 (en) * 2004-02-10 2005-08-11 Diaz Robert L. Intra-operative procedure for post-operative pain control
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
EP4415713A4 (en) 2021-10-14 2025-08-06 Pacira Pharmaceuticals Inc MULTIVESICULAR LIPOSOME FORMULATIONS OF BUPIVACAINE AND THEIR USES
US12070454B1 (en) 2022-05-05 2024-08-27 Pfof Llc Anesthetic nerve block and method
CN119677554A (zh) 2022-05-05 2025-03-21 普络夫有限责任公司 麻醉神经阻滞和方法
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12280149B1 (en) 2024-05-20 2025-04-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
GB9321061D0 (en) * 1993-10-13 1993-12-01 Chiroscience Ltd Analgestic agent and its use
AU704806B2 (en) * 1995-04-13 1999-05-06 Darwin Discovery Limited Levobupivacaine and its use as an anaesthetic in pregnant women

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010277A1 (en) * 1993-10-13 1995-04-20 Chiroscience Limited Analgesic agent and its use

Also Published As

Publication number Publication date
WO1998038996A1 (en) 1998-09-11
NO322446B1 (no) 2006-10-09
PL335561A1 (en) 2000-05-08
HUP0000873A2 (hu) 2000-09-28
DK0981347T3 (da) 2003-09-15
HU225151B1 (en) 2006-07-28
ZA981779B (en) 1999-03-03
ES2199423T3 (es) 2004-02-16
GB9704352D0 (en) 1997-04-23
HUP0000873A3 (en) 2002-10-28
CA2279497A1 (en) 1998-09-11
EP0981347A1 (en) 2000-03-01
DE69814851D1 (de) 2003-06-26
CA2279497C (en) 2009-01-20
KR100516676B1 (ko) 2005-09-22
AU6630498A (en) 1998-09-22
EP0981347B1 (en) 2003-05-21
JP2001513812A (ja) 2001-09-04
KR20000075896A (ko) 2000-12-26
AU730390B2 (en) 2001-03-08
PL190900B1 (pl) 2006-02-28
PT981347E (pt) 2003-09-30
IL131084A0 (en) 2001-01-28
ATE240730T1 (de) 2003-06-15
HK1022651A1 (en) 2000-08-18
DE69814851T2 (de) 2004-01-22
BR9808303A (pt) 2000-05-16
NO994257D0 (no) 1999-09-02
CN1249684A (zh) 2000-04-05
NO994257L (no) 1999-11-02
US5919804A (en) 1999-07-06

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Legal Events

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C06 Publication
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PB01 Publication
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20020828