CN108887444A - A kind of health protection tea of anti-trioxypurine and preparation method thereof - Google Patents

A kind of health protection tea of anti-trioxypurine and preparation method thereof Download PDF

Info

Publication number
CN108887444A
CN108887444A CN201811113247.9A CN201811113247A CN108887444A CN 108887444 A CN108887444 A CN 108887444A CN 201811113247 A CN201811113247 A CN 201811113247A CN 108887444 A CN108887444 A CN 108887444A
Authority
CN
China
Prior art keywords
parts
trioxypurine
health protection
protection tea
tea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811113247.9A
Other languages
Chinese (zh)
Inventor
赵立春
庞宇舟
廖夏云
钟余特
李俊秀
江婵玲
李玉凤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangxi University of Chinese Medicine
Original Assignee
Guangxi University of Chinese Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangxi University of Chinese Medicine filed Critical Guangxi University of Chinese Medicine
Priority to CN201811113247.9A priority Critical patent/CN108887444A/en
Publication of CN108887444A publication Critical patent/CN108887444A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00Tea; Tea substitutes; Preparations thereof
    • A23F3/34Tea substitutes, e.g. matè; Extracts or infusions thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention proposes a kind of health protection teas of anti-trioxypurine, are prepared by following raw material according to parts by weight:30-45 parts of Mao Xu Cao;20-30 parts of cordate houttuynia;15-25 parts of herba lysimachiae;10-23 parts of witloof;12-15 parts of mulberry leaf;5-17 parts of corn stigma.Anti-trioxypurine bag bubble health protection tea prepared by the present invention distinguishes that disease treats for the inherent disease and evil for being led to high lithemia, it is with strong points, raw material sources are wide, at low cost, have effects that clearing and activating the channels and collaterals, row the turbidity stasis of blood, anti-trioxypurine stopping numbness pain, it is curative for effect, obvious, stable, safe, it has no toxic side effect, production is simple, drinks conveniently, target user is extensive, has a vast market application prospect.

Description

A kind of health protection tea of anti-trioxypurine and preparation method thereof
Technical field
The present invention relates to health tea technical fields, and in particular to a kind of anti-trioxypurine health protection tea.
Background technique
High lithemia is that have a kind of substance for being called purine in human body because metabolism gets muddled, cause uric acid in blood increase and A kind of caused metabolic disease, the daily production quantity of internal uric acid and excretion are about equal, in terms of production quantity, three/ First is that from food, three/second is that voluntarily synthesizing in vivo, excretion pathway is then that one third is discharged by enteron aisle, 2/3rds From kidney excretion.As long as above-mentioned various approach have any one to go wrong, uric acid raising will result in.Uric acid rises, because It can hinder the process of blood secretion uric acid, and uric acid be discharged can not.Urate crystal is deposited on synovium of joint, synovial bursa, cartilage And its cause this kind of repeated relapsing inflammatory disease of gout in hetero-organization.Gout is due to monosodium urate salt crystallization (MSU) or to urinate Acid extracellular fluid formed over-saturation state, make its crystal deposit in the tissue and caused by one group of heterologous disease.This disease with It is its feature that can find in joint fluid and tophus, which has single water Monosodium urate crystallization of two-fold photosensitiveness,.Its Clinical symptoms is:High lithemia Characteristic acute arthritis, tophus, interstitial nephritis caused by mass formed by blood stasis and urate crystal, deposition, serious person see that joint is abnormal Shape and dysfunction, often with uric acid lithangiuria.The cause of disease is divided into primary and secondary two major classes.Uric acid is excessively high, can also draw Send out other diseases.In recent ten years, past more rare patient with gout gets up, and is not only late adult onset, and The trend for having also appeared rejuvenation, at a kind of common disease.Clinically, male uric acid normal value:149-416umol/L.Women Uric acid normal value:89-357umo1/L.If being exactly high lithemia occasionally beyond index.
For high lithemia, the prior art usually uses anti-trioxypurine drug or anti-trioxypurine medicinal tea, but this have to human body constitution it is bright Aobvious skewed popularity, and easy to recur, effect is unobvious perhaps unstable or side effect is big, cannot preferably prevent high lithemia and Its complication should not be eaten for a long time especially to hepatic and renal function gastrointestinal disease patient.Therefore, needing to develop a can be suitable for universal people Group and effect is obvious, stablizes, the anti-trioxypurine product of Small side effects, to meet the needs of present market is to treatment high lithemia illness.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of health protection tea and preparation method thereof of anti-trioxypurine, mesh Be, a kind of health protection tea of anti-trioxypurine is provided, by the reasonable compounding of Chinese medicine, has the function that synergy, to being led to The inherent disease and evil of high lithemia, distinguishes that disease treats, with strong points, at low cost, curative for effect, has no toxic side effect, and production is simple, the side of drinking Just, the patient for being applicable in a variety of constitutions is used for a long time.
The present invention provides a kind of health protection tea of anti-trioxypurine, is prepared by following raw material according to parts by weight:Mao Xu Cao 30-45 Part;20-30 parts of cordate houttuynia;15-25 parts of herba lysimachiae;10-23 parts of witloof;12-15 parts of mulberry leaf;5-17 parts of corn stigma.
As further improvement of the invention, it is prepared by following raw material according to parts by weight:33-41 parts of Mao Xu Cao;Fish 22-27 parts of raw meat grass;17-22 parts of herba lysimachiae;15-20 parts of witloof;13-14 parts of mulberry leaf;7-15 parts of corn stigma.
As further improvement of the invention, it is prepared by following raw material according to parts by weight:37 parts of Mao Xu Cao;Cordate houttuynia 25 parts;20 parts of herba lysimachiae;17 parts of witloof;13 parts of mulberry leaf;10 parts of corn stigma.
The present invention further protects a kind of preparation method of the health protection tea of above-mentioned anti-trioxypurine, be prepared according to the following steps and At:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 40-50 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:(20- 50) water is added, after impregnating 1-2h, is heated to 60-80 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 60-80 DEG C of extraction 2h merges the filtrate extracted twice, and being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 80-100 DEG C of frying 30-60min obtains pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 40-50 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
As further improvement of the invention, drying temperature is 45 DEG C.
As further improvement of the invention, soaking time is 1.5h in extraction step, and heating temperature is 70 DEG C.
As further improvement of the invention, frying temperature is 90 DEG C in frying step, and the frying time is 45min.
As further improvement of the invention, the tea bag of the health protection tea of the anti-trioxypurine is put into cup, 200- is added 300mL 40-60 DEG C warm water impregnates 10-20min, takes out tea bag, it can be served for obtained millet paste, 1-3 times daily.
As further improvement of the invention, the tea bag of the health protection tea of anti-trioxypurine can impregnate 1-3 times repeatedly.
The present invention further protects a kind of application of the health protection tea of above-mentioned anti-trioxypurine in treatment high lithemia and its complication.
The effect of Chinese medicine anti-trioxypurine bag bubble health-care tea formula of the present invention, involved raw material, is as follows:
Mao Xu Cao:Sweet light slight bitter, it is cool.Energy clearing heat and removing internal wetness, arranges Shi Lishui, and refrigerant anti-inflammatory can be used as medicine, and it is anxious to be mainly used for treatment Chronic nephritis, cystitis, lithangiuria and rheumatic arthritis.Pharmacological research shows that this product can improve Anemia, in increase Myogenic acid anhydride elimination factor and urine creatinine excretion, be able to suppress proliferation of glomerular mesangial cells and lps induction mesangial cell cause it is scorching because The generation of sub- lps, can be reduced thrombocythemia, reduces blood pressure and reduces prostaglandin and thromboxane generates, hence it is evident that it is small to increase kidney Ball filtration and kidney circulation blood volume, promote the exclusion of toxic metabolite, significantly reduce internal blood uric acid;
Cordate houttuynia:Acrid flavour, it is cold, it is distributed in lung channel.It can clearing heat and detoxicating, detumescence treatment sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach invigorating It helps digestion, is pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from real heat, heat toxin, damp evil, disease heat is controlled.Pharmacological evaluation Show that this product has the effects that antibacterial, antiviral, raising immunity of organisms, diuresis;
Herba lysimachiae:Herb hyoscine, have reducing fever and causing diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation, eliminating inflammation and expelling toxin, desinsection function.It can control Acute, chronic hepatitis, icteric hepatitis, cholecystitis, ephritis, urinary infection, tonsillitis, stomatitis and carbuncle malignant boil treat poison, poisonous snake stings Wound, acute mastitis, dysentery, malaria, empsyxis etc..Pharmacological research shows that this product can have invigorating gallbladder and removing gall-stone and diuresis and stone expeling effect.Herba lysimachiae Alcohol-insoluble substances in polysaccharide component to the main component calcium oxalate monohydrate CaC of lithangiuria2O4·H2The crystallization of O has inhibition to make With can also make blood, urine slant acidity, make the litholysis existing for ability in alkaline environment;
Witloof:With clearing heat and detoxicating, inducing diuresis to remove edema, stomach invigorating and other effects.It is clearing heat and detoxicating;Inducing diuresis to remove edema.Cure mainly jaundice with damp-heat pathogen; Nephritic dropsy;Epigastric distending pain;Loss of appetite also has stomach invigorating and other effects;
Mulberry leaf:Bitter;It is sweet;It is cold in nature, it is distributed in lung channel;Liver Channel.Clearing liver nourishing the liver, dispelling wind and heat from the body;Clearing lung-heat;Improving eyesight.It cures mainly:Wind-heat sense It emits;Wind-warm syndrome is from the beginning of, fever and headache, perspiration and aversion to wind, pectoralgia of coughing;Or dryness of the lung dry cough without phlegm;Dry throat and mouth;In wind-heat and liver-yang It disturbs;Red eye, swell pain.Have effects that be rich in rare element organic selenium, germanium compared with strong anti-oxidation, be natural powerful antioxidant, it can be clear Except interior free yl, make to be accumulated in the intracorporal toxin of people and waste is oxidized, increases the oxygen content in blood, boost metabolism And microcirculation.For hyperlipidemia, hyperglycemia, diabetes, fatty liver, coronary heart disease, hypertension, Combined hepatitis A and B vaccine treatment and The rehabilitation of the postoperative chemicotherapy patient of cancer has extraordinary booster action.Mulberry-leaf extract 1-Deoxynojirimycin and pueraria lobata extract class Flavonoid substance combines and forms a kind of novel substance --- wash the clear sugar element of pancreas, suitable for control hypoglycemic, blood lipid, it is anti-inflammatory the effects of;
Corn stigma:It expels the heat-evil treating stranguria, calming the liver and benefiting the lungs cures mainly gall stone, cholecystitis, diabetes.Pharmaceutical research shows this product Equally there is effect for reducing blood fat to hyperlipidemia patient, there is the effect of diuresis, there is expansion peripheral blood vessel and there is lasting decompression Effect dramatically increases bile secretion and promotes bile excretion, organic matter and slag in bile can be made to reduce, sticky Degree, specific gravity and content of bilirubin reduce, and can be substantially reduced the serum cholesterol content of hypercholesterolemia mouse.
Anti-trioxypurine bag of the present invention steeps health protection tea, for its high situation of uric acid in patient body, to adjust body-internal-circulation as hand Section reaches uric acid level in long-term control volume to enhance body function as bridge, improves purine metabolism ability, inhibits high lithemia The morbidity root of mass formed by blood stasis, controls the generation of hyperuricemia complication, thus the effect realizing that goat is controllable, not recurring, and The generation of other complication of high lithemia initiation can be effectively reduced.Its is with strong points, and effect stability is without side-effects, has promoting menstruation It is the effect of active, row's turbidity stasis of blood, anti-trioxypurine stopping numbness pain, curative for effect, safe and effective, it has no toxic side effect, production is simple, and because Its effective ingredient can be dissolved in rapidly water, drink conveniently, and target user is very extensive, especially:
1, it cannot keep on a diet, often treat with courtesy, liking to drink and eat the people of meat, blocked shot, row on the day of same day uric acid is effectively anti- The breaking-out of model goat;
2, without gout history of attack, but blood uric acid is higher, fears the middle-aged and the old of drug side-effect, can prevent gout and its simultaneously Send out disease;
3, goat recurrent exerbation, uric acid is higher for a long time, and damages with hepatic and renal function, needs to control uric acid level but discomfort The crowd of suitable Long-term taking medicine, prevents and treats gout complication.
Detailed description of the invention
Fig. 1 is the preparation technology figure of the health protection tea of anti-trioxypurine.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the invention is clearly and completely described, Obviously, the embodiment described is the embodiment of part of representative of the invention, rather than whole embodiments, this field are general Other all embodiments obtained belong to protection of the invention to logical technical staff without making creative work Range.
The preparation of the health protection tea of 1 anti-trioxypurine of embodiment
Raw material composition:
30 parts of Mao Xu Cao;20 parts of cordate houttuynia;15 parts of herba lysimachiae;10 parts of witloof;12 parts of mulberry leaf;5 parts of corn stigma.
Preparation method:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 40 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:20 are added Water after impregnating 1h, is heated to 60 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 60 DEG C of extraction 2h, close And the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 80 DEG C of frying 30min obtain pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 40 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
The preparation of the health protection tea of 2 anti-trioxypurine of embodiment
Raw material composition:
45 parts of Mao Xu Cao;30 parts of cordate houttuynia;25 parts of herba lysimachiae;23 parts of witloof;15 parts of mulberry leaf;17 parts of corn stigma.
Preparation method:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 50 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:50 are added Water after impregnating 2h, is heated to 80 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 80 DEG C of extraction 2h, close And the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 100 DEG C of frying 60min obtain pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 50 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
The preparation of the health protection tea of 3 anti-trioxypurine of embodiment
Raw material composition:
33 parts of Mao Xu Cao;22 parts of cordate houttuynia;17 parts of herba lysimachiae;15 parts of witloof;13 parts of mulberry leaf;7 parts of corn stigma.
Preparation method:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 42 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:30 are added Water after impregnating 1.5h, is heated to 65 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 65 DEG C of extraction 2h, Merge the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 85 DEG C of frying 40min obtain pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 42 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
The preparation of the health protection tea of 4 anti-trioxypurine of embodiment
Raw material composition:
41 parts of Mao Xu Cao;27 parts of cordate houttuynia;22 parts of herba lysimachiae;20 parts of witloof;14 parts of mulberry leaf;15 parts of corn stigma.
Preparation method:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 47 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:40 are added Water after impregnating 1.5h, is heated to 75 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 75 DEG C of extraction 2h, Merge the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 90 DEG C of frying 50min obtain pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 47 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
The preparation of the health protection tea of 5 anti-trioxypurine of embodiment
Raw material composition:
37 parts of Mao Xu Cao;25 parts of cordate houttuynia;20 parts of herba lysimachiae;17 parts of witloof;13 parts of mulberry leaf;10 parts of corn stigma.
Preparation method:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are washed Only, 45 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:25 are added Water after impregnating 1.5h, is heated to 70 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 70 DEG C of extraction 2h, Merge the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf after sterilizing Chopping is uniformly mixed, and 90 DEG C of frying 45min obtain pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed to the prefabricated of step S3 preparation On tea, 45 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
The health protection tea of 6 anti-trioxypurine of embodiment is brewed
The tea bag of the health protection tea of the anti-trioxypurine is put into cup, 200-300mL 40-60 DEG C warm water is added and impregnates 10- 20min takes out tea bag, and it can be served for obtained millet paste, and 1-3 times daily, every packet tea bag impregnates 1-3 times repeatedly.
Reference examples 1 are prepared according to the formula of patent ZL 201710639176.5 " anti-trioxypurine health protection tea " a kind of
Raw material composition:1.5 parts of cape jasmine;1 part of mulberry root;1.5 parts of pueraria lobata;1 part of balsam pear;3 parts of cassia bark;2 parts of lemon.
Preparation method:It takes above-mentioned formula material dry product to be uniformly mixed in proportion to crush, crosses 50 meshes, be distributed into tea bag, often 10 grams of bag is made.
1 zoopery of test example
Experimental animal:
Kunming mouse, weight 20-25g, half male and half female, mouse enter cleaner assay room raising 7d, observe its activity, into Start to test after food, stool and urine are without exception.It is raised with all steel rat breeding cage, male and female divide cage.It is raised with mouse complete granular Material is fed, by trained keeper's special messenger raising management.Animal housing's illumination is sufficient, and heating ventilation and air-conditioning equipment is good, room 18~25 DEG C of temperature, relative humidity 50%~70%, laboratory routinely periodically sterilizes.
The foundation of antihyperuricemic disease mouse model:
Oxygen tremnbles acid clock dosage as 300mg/kg.Oxygen is tremnbled, and sour clock solution is small as injected abdominal cavity, and except normal group, remaining is infused Penetrate OA solution.Daily 9:00am is injected, continuous injection seven days.This experiment is administered using intraperitoneal injection.It carefully grabs small Accurate injection abdominal cavity is injected intraperitoneally in mouse.
Experimental method:
Mouse is randomly divided into 9 groups, is i.e. experimental group 1-5, normally organizes 6, blank control group 7, control group 8 and control group 9, often Group 10, half male and half female.Every group of mouse of experimental group 1-5 respectively corresponds the sample solution of stomach-filling embodiment of the present invention 1-5 preparation, fills Stomach content is the millet paste that 5g health protection tea is brewed with 200mL warm water.Experimental mice is administered according to above method, is filled every time Liquid 10mL/10g soluble in the stomach;Normal group 6 and 7 stomach-filling same amount of normal saline of blank control group;The preparation of 8 stomach-filling reference examples 1 of control group Health protection tea, stomach-filling content are that 5g health protection tea is dissolved in solution obtained in 200mL distilled water, each stomach-filling solution 10mL/ 10g;9 stomach-filling anti-trioxypurine drug allopurinol of control group, stomach-filling content are that 5g allopurinol is dissolved in 200mL distilled water to obtain Solution, each stomach-filling solution 10mL/10g.Before testing after fasting (can't help water) 12h, experimental group gastric infusion 1 time a day, even It is 14 days continuous.Eyeball takes blood after having injected 1 hour for last 1 time, is put into centrifuge tube, puts to death mouse, dissect at once mouse take out it is small The half liver organization of mouse is put into the secondary property sampling pipe of the 50mL-equipped with physiological saline and rinses.The other half is put into equipped with formal In the disposable sampling pipe of the 50mL of woods solution.Mouse kidney is taken to be put into the disposable sampling pipe of 50mL equipped with formalin solution In.Mice serum uric acid, xanthine oxidase (XOD enzyme) vigor and liver XOD enzyme activity are measured respectively.
Experimental result is shown in Table 1.
1 each group mouse data result of table
As seen from the above table, the anti-trioxypurine health protection tea of 1-5 of embodiment of the present invention preparation has the function of obvious anti-trioxypurine, simultaneously The vigor of serum xanthin oxydase and liver xanthine oxidase can be significantly inhibited, so that the generation of uric acid is reduced, so that urine Acid forms crystallization not in the tissue cavities such as joint.Although the anti-trioxypurine tea and anti-trioxypurine drug allopurinol of reference examples preparation also can The content and XOD enzyme activity of uric acid in serum are enough reduced, but effect is obviously not so good as the health protection tea of preparation of the embodiment of the present invention, because This, the present invention has apparent advantage in contrast, has broad application prospects.
Case citing:
Patient 1:Zhang, male, 53 years old, Top Management.Left 1st articulationes metatarsophalangeae red and swollen heat pain 3 days, laboratory are had a blood test uric acid Value 655umol/L.Right foot big toe redness and swelling of joints 6 days.There is right sufficient big toe redness and swelling of joints in two years ago in patient.It is poor in local hospital Blood uric acid is higher, is diagnosed as gout.Colchicum bases drug therapy is given, the state of an illness is controlled.Patient's private prosecution hypertension history 5 Year, fatty liver 4 years.In view of Western medicine side effects of pharmaceutical drugs are larger, treated then using anti-trioxypurine health protection tea of the present invention.Take this hair Bright health protection tea 3 days, 3 times a day, 1 bag every time, every bag 5-7 grams, redness abatement, pain relief.Treatment was taken according to quantity through 14 days, Red and swollen, heat pain all disappears, and freely, remaining symptom is substantially reduced for walking;It continuously takes 35 days, checks blood uric acid value 390umol/ L.It advises it to continue to take 14 days.Follow-up no relapse.
Patient 2:Side certain, women, 39 years old, General Office Clerk.It eats seafood from small hobby, pluck, and normal blocked shot, happiness Vigorously have the beer.Last year unit checks UP, and blood uric acid has been up to 602umol/L, although uric acid level is exceeded without uncomfortable. Take health protection tea of the invention 10 days, 3 times a day, 1 bag every time, every bag 5-7 grams, urine becomes clear by turbid;Check blood uric acid value 401umol/L.Continuation is taken 5 days according to quantity, is checked blood uric acid value 345umol/L, is reached in range of normal value.It advises it to continue and takes 5 It.Follow-up no relapse.
Patient 3:Mr. Wang, male, 67 years old, retired old man.Whole body arthralgia, the migrans pain of ankle, knee joint is repeatedly Breaking-out more than 4 years.Light night in daytime very, need to take Fenbid, Bufferin analgesic.Treatment burst swelling and pain again in first 5 days, it is handicapped.Disease See redness at the 1st articulationes metatarsophalangeae of biped, deformity, color is red, Pi Wengao, purplish tongue, yellow and greasy fur, wiry and frequent pulse, pain, with waist Bitterly, enuresis nocturna up to 3-4 times.Have a blood test uric acid 647umol/L in laboratory.Take health protection tea of the invention 14 days, 3 times a day, every time 1 Bag, every bag 5-7 grams, symptom is relieved, and still has deformity, tenderness, and waist is tingle, frequent urination at night.It continuously takes 35 days, red and swollen, heat Pain all disappears, and freely, remaining symptom is substantially reduced for walking;Check blood uric acid value 407umol/L.It advises it to continue to take 20 days.With Visit no relapse.
Those skilled in the art is not under conditions of departing from the spirit and scope of the present invention that claims determine, also Various modifications can be carried out to the above content.Therefore the scope of the present invention is not limited in above explanation, but by The range of claims determines.

Claims (10)

1. a kind of health protection tea of anti-trioxypurine, which is characterized in that be prepared by following raw material according to parts by weight:Mao Xu Cao 30-45 Part;20-30 parts of cordate houttuynia;15-25 parts of herba lysimachiae;10-23 parts of witloof;12-15 parts of mulberry leaf;5-17 parts of corn stigma.
2. a kind of health protection tea of anti-trioxypurine according to claim 1, which is characterized in that prepared by following raw material according to parts by weight It forms:33-41 parts of Mao Xu Cao;22-27 parts of cordate houttuynia;17-22 parts of herba lysimachiae;15-20 parts of witloof;13-14 parts of mulberry leaf;Corn stigma 7-15 parts.
3. a kind of health protection tea of anti-trioxypurine according to claim 1, which is characterized in that prepared by following raw material according to parts by weight It forms:37 parts of Mao Xu Cao;25 parts of cordate houttuynia;20 parts of herba lysimachiae;17 parts of witloof;13 parts of mulberry leaf;10 parts of corn stigma.
4. a kind of preparation method of the health protection tea of anti-trioxypurine described in -3 any claims according to claim 1, which is characterized in that It is prepared according to the following steps:
S1. the pretreatment of medicinal material:Mao Xu Cao, cordate houttuynia, herba lysimachiae, witloof, mulberry leaf and corn stigma are weighed in proportion, are cleaned, 40- 50 DEG C of drying, radiation sterilizing are spare;
S2. the extraction of herba lysimachiae and corn stigma:The herba lysimachiae of sterilizing and corn stigma are mixed, according to solid-to-liquid ratio 1:(20-50) adds Enter water, after impregnating 1-2h, be heated to 60-80 DEG C, extracts 2h, filtering, filter residue is according to solid-to-liquid ratio 1:10 are added water, continue 60-80 DEG C 2h is extracted, merges the filtrate extracted twice, being concentrated into density is 0.7-0.9g/cm3, spare;
S3. the frying of Mao Xu Cao, cordate houttuynia, witloof and mulberry leaf:By Mao Xu Cao, cordate houttuynia, witloof and the mulberry leaf cutting after sterilizing, It is uniformly mixed, 80-100 DEG C of frying 30-60min obtains pre- tea making, spare;
S4. the preparation of anti-trioxypurine health protection tea:Concentrate prepared by step S2 is uniformly sprayed in the pre- tea making of step S3 preparation, 40-50 DEG C drying, be fitted into the nonwoven fabric belts of sterilizing, every bag of 5-7g, envelope to get.
5. a kind of preparation method of the health protection tea of anti-trioxypurine described in a claim according to claim 4, which is characterized in that The drying temperature is 45 DEG C.
6. a kind of preparation method of the health protection tea of anti-trioxypurine described in a claim according to claim 4, which is characterized in that Soaking time is 1.5h in the extraction step, and heating temperature is 70 DEG C.
7. a kind of preparation method of the health protection tea of anti-trioxypurine described in a claim according to claim 4, which is characterized in that Frying temperature is 90 DEG C in the frying step, and the frying time is 45min.
8. a kind of health protection tea of anti-trioxypurine according to claim 1, which is characterized in that by the tea of the health protection tea of the anti-trioxypurine Bag is put into cup, and 200-300mL 40-60 DEG C warm water is added and impregnates 10-20min, takes out tea bag, and it can be served for obtained millet paste, 1-3 times daily.
9. a kind of health protection tea of anti-trioxypurine according to claim 1, which is characterized in that the tea bag of the health protection tea of the anti-trioxypurine It can impregnate 1-3 times repeatedly.
10. a kind of health protection tea of anti-trioxypurine described in -3 any claims is in treatment high lithemia and its concurrent according to claim 1 Application in disease.
CN201811113247.9A 2018-09-25 2018-09-25 A kind of health protection tea of anti-trioxypurine and preparation method thereof Pending CN108887444A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811113247.9A CN108887444A (en) 2018-09-25 2018-09-25 A kind of health protection tea of anti-trioxypurine and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811113247.9A CN108887444A (en) 2018-09-25 2018-09-25 A kind of health protection tea of anti-trioxypurine and preparation method thereof

Publications (1)

Publication Number Publication Date
CN108887444A true CN108887444A (en) 2018-11-27

Family

ID=64360099

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811113247.9A Pending CN108887444A (en) 2018-09-25 2018-09-25 A kind of health protection tea of anti-trioxypurine and preparation method thereof

Country Status (1)

Country Link
CN (1) CN108887444A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467392A (en) * 2019-01-23 2020-07-31 梁尚贤 A Chinese medicinal composition for treating or relieving gout
CN112262983A (en) * 2020-10-27 2021-01-26 深圳市淳睿科技发展有限公司 Vegetable and fruit composition with effect of resisting saccharified uric acid gout and preparation method thereof
CN112273503A (en) * 2019-07-26 2021-01-29 蒋鹤 Tea bag and preparation method and application method thereof
CN114885996A (en) * 2022-05-20 2022-08-12 福建糖小六生物科技有限公司 Seven-wind tea with uric acid reducing function and preparation method thereof
CN114984148A (en) * 2022-06-17 2022-09-02 南阳九方中医药有限公司 Substitutional tea for reducing uric acid and relieving gout and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100040707A1 (en) * 2004-10-26 2010-02-18 Violetta Iotsova Stone Ingestible compositions containing extracts
CN107281415A (en) * 2017-07-05 2017-10-24 吴淦秋 Chinese medicine anti-trioxypurine bag bubble health-care tea formula and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100040707A1 (en) * 2004-10-26 2010-02-18 Violetta Iotsova Stone Ingestible compositions containing extracts
CN107281415A (en) * 2017-07-05 2017-10-24 吴淦秋 Chinese medicine anti-trioxypurine bag bubble health-care tea formula and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
复禾健康: "痛风患者不妨常吃这些食物", 《HTTPS://NEWS.FH21.COM.CN/HYZX/SHWS/CHI/5356227.HTML》 *
山羊0R3LUL7RU8: "高尿酸的"死对头",每天坚持喝一杯,尿酸降不停,痛风不来扰", 《HTTP://WWW.360DOC.COM/CONTENT/18/0619/11/53527444_763515024.SHTML》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111467392A (en) * 2019-01-23 2020-07-31 梁尚贤 A Chinese medicinal composition for treating or relieving gout
CN112273503A (en) * 2019-07-26 2021-01-29 蒋鹤 Tea bag and preparation method and application method thereof
CN112262983A (en) * 2020-10-27 2021-01-26 深圳市淳睿科技发展有限公司 Vegetable and fruit composition with effect of resisting saccharified uric acid gout and preparation method thereof
CN114885996A (en) * 2022-05-20 2022-08-12 福建糖小六生物科技有限公司 Seven-wind tea with uric acid reducing function and preparation method thereof
CN114984148A (en) * 2022-06-17 2022-09-02 南阳九方中医药有限公司 Substitutional tea for reducing uric acid and relieving gout and preparation method

Similar Documents

Publication Publication Date Title
CN108887444A (en) A kind of health protection tea of anti-trioxypurine and preparation method thereof
CN102198262B (en) Chinese medicine preparation for treating infant rotavirus enteritis and preparation method thereof
CN104366636A (en) Gynura procumbens compound preparation as well as preparation method and application thereof
CN100531751C (en) External plaster for treating child cold diarrhea and preparing method
CN103099959B (en) Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof
CN102772781B (en) Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof
CN104187172A (en) Functional feed for treating enterogastritis diseases of turtles and preparation method of functional feed
CN110215499A (en) A kind of anti-trioxypurine integration of drinking and medicinal herbs drink
CN102861287B (en) Chinese medicinal composition for treating damp-heat invasion blood stasis diabetic foot and preparation method thereof
CN102772712B (en) Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot
CN104815192A (en) Pharmaceutical composition for treating hypertension and application of pharmaceutical composition
CN108837121A (en) A kind of Chinese medicine composition and preparation method thereof for treating high lithemia
CN103705796B (en) A kind of pharmaceutical composition for the treatment of diarrhoea and preparation method thereof
CN105287748B (en) The Chinese materia medica preparation and preparation method thereof for treating hyperuricemia
CN100589834C (en) Therapeutic agent for respiration diseases
CN110354222A (en) It is a kind of for treating the external drug of gout
CN106266109B (en) It is a kind of to treat Chinese medicine composition of calculi in urinary system and preparation method thereof
CN109820943A (en) A kind of strong medicine preparation and preparation method thereof for treating gout
CN109498731A (en) A kind of tonifying speen and tonifying kidney tune sugar-pill and preparation method thereof for treating diabetes B Pishenqixu syndrome
CN102198261B (en) Chinese medicinal preparation for treating elder chronic colitis and preparation method thereof
KR100712659B1 (en) Herbal composition for treatment and prevention of diabetes and diabetic complications
CN103705639A (en) Chinese medicinal preparation for treating hydrocephalus
CN102068670B (en) Chinese medicinal composition for treating hyperlipidemia
CN109663081B (en) Zhuang medicine composition for treating functional unsmooth urination of bladder and preparation method thereof
CN105194676A (en) Medicine composition for treating hyperlipemia and preparation method of medicine composition

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20181127

RJ01 Rejection of invention patent application after publication