CN114984148A - Substitutional tea for reducing uric acid and relieving gout and preparation method - Google Patents
Substitutional tea for reducing uric acid and relieving gout and preparation method Download PDFInfo
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- 201000005569 Gout Diseases 0.000 title claims abstract description 30
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title claims abstract description 29
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title claims abstract description 27
- 229940116269 uric acid Drugs 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 241001122767 Theaceae Species 0.000 title description 29
- 240000008042 Zea mays Species 0.000 claims abstract description 40
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 31
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 31
- 235000005822 corn Nutrition 0.000 claims abstract description 31
- 238000010438 heat treatment Methods 0.000 claims abstract description 18
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 17
- 241001598107 Imperata Species 0.000 claims abstract description 17
- 241000234435 Lilium Species 0.000 claims abstract description 12
- 240000000249 Morus alba Species 0.000 claims abstract description 12
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 12
- 235000007542 Cichorium intybus Nutrition 0.000 claims abstract description 11
- 239000008213 purified water Substances 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000007244 Zea mays Nutrition 0.000 claims abstract description 9
- 229940089639 cornsilk Drugs 0.000 claims abstract description 9
- 239000001231 zea mays silk Substances 0.000 claims abstract description 9
- 238000000034 method Methods 0.000 claims abstract description 8
- 244000269722 Thea sinensis Species 0.000 claims abstract 9
- 244000298479 Cichorium intybus Species 0.000 claims abstract 3
- 238000002156 mixing Methods 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 17
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- 230000001954 sterilising effect Effects 0.000 claims description 12
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- 238000001914 filtration Methods 0.000 claims description 10
- 239000012535 impurity Substances 0.000 claims description 10
- 239000011259 mixed solution Substances 0.000 claims description 10
- 238000002791 soaking Methods 0.000 claims description 10
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 239000011552 falling film Substances 0.000 claims description 5
- 238000011049 filling Methods 0.000 claims description 5
- 238000002386 leaching Methods 0.000 claims description 5
- 238000009928 pasteurization Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
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- DMASLKHVQRHNES-UPOGUZCLSA-N (3R)-beta,beta-caroten-3-ol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C DMASLKHVQRHNES-UPOGUZCLSA-N 0.000 abstract description 2
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- 150000003797 alkaloid derivatives Chemical class 0.000 abstract description 2
- DMASLKHVQRHNES-ITUXNECMSA-N beta-cryptoxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CCCC2(C)C DMASLKHVQRHNES-ITUXNECMSA-N 0.000 abstract description 2
- 235000002360 beta-cryptoxanthin Nutrition 0.000 abstract description 2
- 230000000975 bioactive effect Effects 0.000 abstract description 2
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- IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 description 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
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- 206010065941 Central obesity Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 201000001431 Hyperuricemia Diseases 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 206010046337 Urate nephropathy Diseases 0.000 description 1
- 208000009911 Urinary Calculi Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
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- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
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- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a substitutional tea for reducing uric acid and relieving gout and a preparation method thereof, wherein the substitutional tea comprises the following raw materials, by weight, 500-600 parts of purified water, 20-30 parts of corn stigma, 6-10 parts of mulberry leaves, 6-10 parts of lily, 3-7 parts of fresh lalang grass rhizome and 3-7 parts of chicory. Compared with the prior art, the method has the advantages that: the main material is corn silk, which is a very common medicinal material with low cost, and the research shows that: the corn stigma contains various bioactive components such as polysaccharide, polyphenol, phytosterol, alkaloid, cryptoxanthin, saponin, organic acid and the like, can discharge uric acid in a body as soon as possible, has the effects of obviously reducing uric acid, has the characteristics of reducing blood fat, resisting inflammation and diminishing swelling and the like besides the corn stigma and auxiliary materials such as mulberry leaves, lily, fresh lalang grass rhizome and the like, has smaller side effect compared with western medicines, does not need complicated decoction of drinkers, can be directly drunk only by simple heating, and is very convenient.
Description
Technical Field
The invention relates to the technical field of substitutional tea for reducing uric acid and relieving gout, in particular to substitutional tea for reducing uric acid and relieving gout and a preparation method thereof.
Background
Gout is crystal-related arthropathy caused by deposition of mono-natriuretic urate, is directly related to hyperuricemia caused by purine metabolic disorder or reduced uric acid excretion, particularly acute characteristic arthritis and chronic gout stone diseases, mainly comprise acute paroxysmal arthritis, gout stone formation, gout stone chronic arthritis, urate nephropathy and urate urinary tract stones, and can cause joint disability and renal insufficiency in serious patients. Gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes, cardiovascular diseases and other manifestations. Gout is mostly seen in middle-aged men, women account for only 5 percent, and gout is mainly developed in postmenopausal women and tends to be younger. According to investigation, nearly 90% of gout patients in China adopt oral western medicines for reducing acid to treat gout, including colchicine, non-steroidal anti-inflammatory drugs, glucocorticoids and the like. In fact, western medicines only have the effects of relieving and relieving pain, and after long-term administration, the medicine can damage heart, brain, liver and kidney, and has many unexpected side effects, so that gout patients can not be compensated. Compared with western medicines, the decoction of the traditional Chinese medicines is troublesome for most people, the processed compound tea can overcome the defects, can be directly drunk only by simple heating, and has the effect of reducing uric acid.
Disclosure of Invention
The invention aims to solve the technical problem of providing the substitutional tea which has small side effect and is convenient to drink and used for reducing uric acid and relieving gout and a preparation method thereof.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: a substitute tea for reducing uric acid and relieving gout and a preparation method thereof comprise the following raw materials, by weight, 500-600 parts of purified water, 20-30 parts of corn stigma, 6-10 parts of mulberry leaves, 6-10 parts of lily, 3-7 parts of fresh lalang grass rhizome and 3-7 parts of chicory. As an improvement, the method comprises the following steps:
the method comprises the following steps: preparing fresh corn silk as a raw material, removing impurities and cleaning to obtain clean corn silk; crushing corn stigma, mixing with purified water, stirring to obtain mixed solution of corn stigma, filtering with 100 mesh filter screen, pouring the mixed solution of corn stigma into double-effect falling film evaporator, and concentrating to obtain concentrated solution of corn stigma filtrate;
step two: removing impurities from folium Mori and fresh lalang grass rhizome, cleaning, pouring into a mixing container, pouring the obtained concentrated solution of stigma Maydis filtrate into the mixing container, mixing, and soaking for 30 min; after soaking, taking out the mulberry leaves and the fresh lalang grass rhizome to leave a leaching solution for later use;
step three: and (3) pouring the leachate obtained in the step two into a heating vessel, heating to 75 ℃, then pouring lily and chicory, heating at 80-95 ℃ for five minutes, filtering by using a 160-mesh filter screen, stirring, sterilizing after stirring, obtaining the substitute tea for reducing uric acid and relieving gout after sterilizing, and then filling the substitute tea into bags to obtain the substitute tea.
As an improvement, the stirring time in the third step is 30-60 minutes.
As an improvement, the sterilization treatment mode in the third step is pasteurization.
The invention has the following advantages: the main material of the invention is corn stigma which is a very common medicinal material with low cost, and researches show that: the stigma Maydis solution contains various bioactive components such as polysaccharide, polyphenol, phytosterol, alkaloid, cryptoxanthin, saponin, organic acid, etc., can discharge uric acid in vivo out of body as soon as possible, has effect of reducing uric acid, and also has effects of reducing blood sugar, reducing blood lipid, lowering blood pressure, etc., and can be used for treating various diseases such as diabetes, dysuresia, hypertension, cholelithiasis, hyperlipemia, etc. The tea substitute disclosed by the invention has the obvious effect of reducing uric acid, and also has the characteristics of reducing blood fat, resisting inflammation and reducing swelling, compared with western medicines, the tea substitute has smaller side effect, does not need complicated decoction of drinkers, can be directly drunk only by simple heating, is very convenient, and is suitable for long-term drinking of patients to achieve the effect of reducing uric acid and relieving gout.
Detailed Description
The present invention will be described in further detail with reference to examples.
Example 1, a substitutional tea for reducing uric acid and relieving gout and a preparation method thereof, wherein the substitutional tea comprises the following raw materials, by weight, 500 parts of purified water, 20 parts of corn stigma, 6 parts of mulberry leaves, 6 parts of lily, 3 parts of fresh lalang grass rhizome and 3 parts of chicory.
The preparation and the production of the substitutional tea comprise the following steps:
the method comprises the following steps: preparing fresh corn silk as a raw material, removing impurities and cleaning to obtain clean corn silk; crushing corn stigma, mixing with purified water, stirring to obtain mixed solution of corn stigma, filtering with 100 mesh filter screen, pouring the mixed solution of corn stigma into double-effect falling film evaporator, and concentrating to obtain concentrated solution of corn stigma filtrate;
step two: removing impurities from folium Mori and fresh lalang grass rhizome, cleaning, pouring into a mixing container, pouring the obtained concentrated solution of stigma Maydis filtrate into the mixing container, mixing, and soaking for 30 min; after soaking, taking out the mulberry leaves and the fresh lalang grass rhizome to leave a leaching solution for later use;
step three: and (3) pouring the leachate obtained in the step two into a heating vessel, heating to 75 ℃, then pouring lily and chicory, heating for five minutes at the temperature of 80-95 ℃, filtering by using a 160-mesh filter screen, stirring for 30 minutes, performing sterilization treatment after stirring is finished, obtaining the substitutive tea for reducing uric acid and relieving gout after sterilization, and then filling the substitutive tea into bags to obtain the substitutive tea.
The embodiment 2 discloses a substitutional tea for reducing uric acid and relieving gout and a preparation method thereof, and the substitutional tea comprises the following raw materials, by weight, 550 parts of purified water, 25 parts of corn stigma, 8 parts of mulberry leaves, 8 parts of lily, 5 parts of fresh lalang grass rhizome and 5 parts of chicory.
The preparation and the production of the substitutional tea comprise the following steps:
the method comprises the following steps: preparing fresh corn stigma as a raw material, removing impurities, and cleaning to obtain clean corn stigma; crushing corn stigma, mixing with purified water, stirring to obtain mixed solution of corn stigma, filtering with 100 mesh filter screen, pouring the mixed solution of corn stigma into double-effect falling film evaporator, and concentrating to obtain concentrated solution of corn stigma filtrate;
step two: removing impurities from folium Mori and fresh lalang grass rhizome, cleaning, pouring into a mixing container, pouring the obtained concentrated solution of stigma Maydis filtrate into the mixing container, mixing, and soaking for 30 min; after soaking, taking out the mulberry leaves and the fresh lalang grass rhizome to leave a leaching solution for later use;
step three: and (3) pouring the leachate obtained in the step two into a heating vessel, heating to 75 ℃, then pouring lily and chicory, heating for five minutes at the temperature of 80-95 ℃, filtering by using a 160-mesh filter screen, stirring for 45 minutes, performing sterilization treatment after stirring is finished, obtaining the substitutive tea for reducing uric acid and relieving gout after sterilization, and then filling the substitutive tea into bags to obtain the substitutive tea.
Example 3, a substitutional tea for reducing uric acid and relieving gout and a preparation method thereof, comprising the following raw materials, by weight, 600 parts of purified water, 30 parts of corn stigma, 10 parts of mulberry leaf, 10 parts of lily, 7 parts of fresh lalang grass rhizome, and 7 parts of chicory.
The preparation and the production of the substitutional tea comprise the following steps:
the method comprises the following steps: preparing fresh corn silk as a raw material, removing impurities and cleaning to obtain clean corn silk; crushing corn stigma, mixing with purified water, stirring to obtain mixed solution of corn stigma, filtering with 100 mesh filter screen, pouring the mixed solution of corn stigma into double-effect falling film evaporator, and concentrating to obtain concentrated solution of corn stigma filtrate;
step two: removing impurities from folium Mori and fresh lalang grass rhizome, cleaning, pouring into a mixing container, pouring the obtained concentrated solution of stigma Maydis filtrate into the mixing container, mixing, and soaking for 30 min; after soaking, taking out the mulberry leaves and the fresh lalang grass rhizome to leave a leaching solution for later use;
step three: and (3) pouring the leachate obtained in the step two into a heating vessel, heating to 75 ℃, then pouring lily and chicory, heating for five minutes at the temperature of 80-95 ℃, filtering by using a 160-mesh filter screen, stirring for 60 minutes, performing sterilization treatment after stirring is finished, obtaining the substitutive tea for reducing uric acid and relieving gout after sterilization, and then filling the substitutive tea into bags to obtain the substitutive tea.
Although the invention has been described in detail hereinabove with respect to a general description and specific embodiments thereof, it will be apparent to those skilled in the art that modifications or improvements may be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.
Claims (4)
1. A substitutional tea for reducing uric acid and relieving gout and a preparation method thereof are characterized in that: the formula comprises the following raw materials, by weight, 500-600 parts of purified water, 20-30 parts of corn stigma, 6-10 parts of mulberry leaves, 6-10 parts of lily, 3-7 parts of fresh lalang grass rhizome and 3-7 parts of chicory.
2. The substitutional tea and the preparation method for reducing uric acid and relieving gout according to claim 1 are characterized in that: the method comprises the following steps:
the method comprises the following steps: preparing fresh corn silk as a raw material, removing impurities and cleaning to obtain clean corn silk; crushing corn stigma, mixing with purified water, stirring to obtain mixed solution of corn stigma, filtering with 100 mesh filter screen, pouring the mixed solution of corn stigma into double-effect falling film evaporator, and concentrating to obtain concentrated solution of corn stigma filtrate;
step two: removing impurities from folium Mori and fresh lalang grass rhizome, cleaning, pouring into a mixing container, pouring the obtained concentrated solution of stigma Maydis filtrate into the mixing container, mixing, and soaking for 30 min; after soaking, taking out the mulberry leaves and the fresh lalang grass rhizome, and leaving a leaching solution for later use;
step three: and (3) pouring the leachate obtained in the step two into a heating vessel, heating to 75 ℃, then pouring lily and chicory, heating at 80-95 ℃ for five minutes, filtering by using a 160-mesh filter screen, stirring, sterilizing after stirring, obtaining the substitute tea for reducing uric acid and relieving gout after sterilizing, and then filling the substitute tea into bags to obtain the substitute tea.
3. The substitutional tea and the preparation method for reducing uric acid and relieving gout according to claim 2 are characterized in that: the stirring time in the third step is 30-60 minutes.
4. The substitutional tea and the preparation method for reducing uric acid and relieving gout according to claim 2 are characterized in that: the sterilization mode in the third step is pasteurization.
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CN202210693152.9A CN114984148A (en) | 2022-06-17 | 2022-06-17 | Substitutional tea for reducing uric acid and relieving gout and preparation method |
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CN116195698A (en) * | 2023-03-22 | 2023-06-02 | 潘柳臻 | Preparation method of plant beverage with uric acid reducing function |
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CN108887444A (en) * | 2018-09-25 | 2018-11-27 | 广西中医药大学 | A kind of health protection tea of anti-trioxypurine and preparation method thereof |
CN113288978A (en) * | 2021-07-14 | 2021-08-24 | 李智民 | Composition for treating gout and preparation method and application thereof |
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CN108887444A (en) * | 2018-09-25 | 2018-11-27 | 广西中医药大学 | A kind of health protection tea of anti-trioxypurine and preparation method thereof |
CN113288978A (en) * | 2021-07-14 | 2021-08-24 | 李智民 | Composition for treating gout and preparation method and application thereof |
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CN116195698A (en) * | 2023-03-22 | 2023-06-02 | 潘柳臻 | Preparation method of plant beverage with uric acid reducing function |
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