CN108850657A - Improve the Chinese herbal feed additive and preparation method thereof of chicken disease resistance - Google Patents
Improve the Chinese herbal feed additive and preparation method thereof of chicken disease resistance Download PDFInfo
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- CN108850657A CN108850657A CN201811083129.8A CN201811083129A CN108850657A CN 108850657 A CN108850657 A CN 108850657A CN 201811083129 A CN201811083129 A CN 201811083129A CN 108850657 A CN108850657 A CN 108850657A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
- A23K10/26—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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Abstract
The invention discloses the Chinese herbal feed additives and preparation method thereof for improving chicken disease resistance.Chinese herbal feed additive of the present invention is made of following bulk pharmaceutical chemicals：30-35 parts of root of kirilow rhodiola, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, 12-18 parts of wilsonii, 6-10 parts of Shitake Mushroom P.E, 6-10 parts of viola mandshurica, 6-10 parts of mulberry leaf, 6-10 parts of oyster shell powder, 2-5 parts of Radix Glycyrrhizae.The present invention further discloses the method for preparing the Chinese herbal feed additive.According to the test result of premunition as it can be seen that after Chinese herbal feed additive of the present invention is incorporated into the daily ration of chicken, chicken can be effectively improved for the resistance of newcastle disease virus, extremely significant reduction morbidity and mortality effectively promote the premunition of chicken.During using Chinese herbal feed additive of the present invention, chicken is not observed and any adverse reaction occurs, illustrates that Chinese herbal feed additive of the present invention has good safety for chicken.
Description
Technical field
The present invention relates to the Chinese herbal feed additives for improving poultry disease resistance, more particularly to improve in chicken disease resistance
Medicine feed addictive and preparation method thereof belongs to the Chinese medicine therapy field for improving chicken immuological function.
Background technique
Fowl respiratory diseases are one of the high morbidities in poultry diease, and there are many clinical upper respiratory disease, as infectious laryngotracheitis,
Infective bronchitis, chronic respiratory disease, infective rhinitis, newcastle disease, bird flu, chicken pox and avian Aspergillosis
Deng.
Infectious bronchitis of chicken is that a kind of acute high degree in contact of the chicken as caused by infectious bronchitis virus is exhaled
Inhale road transmission disease.It faces to examine and is characterized in expiratory dyspnea, issues rale, cough, mouth breathing, sneezing.If cause of disease is not kidney
Intercurrent disease does not occur for pathotype strain, and the death rate is generally very low.Laying hen infection is usually cashed egg production and is reduced, the quality of egg
Decline.This disease is widely current in the important epidemic disease for all over the world, being poultry husbandry.
Newcastle disease (New Castle disease), also known as philippine fowl disease or pseudo- checken pest, are as caused by paramyxovirus
Highly contagious disease is often in acute sepsis shape.It is mainly characterized by expiratory dyspnea, just dilute, neurological disorders, mucous membrane and serous coat
Bleeding.The death rate is high, endangers poultry husbandry serious.Nineteen twenty-six first discovery is sent out in Britain's new city again soon in Indonesia
Existing, there are popular record in countries in the world.There is two class of velogen strain and low virulent strain.Virus is divided into less toxic power type (i.e. delayed type), medium
Virulence type (hair style in i.e.), 3 type of strong virus force type (i.e. anaphylactic type).Most high intensity virulent strains often belong to thermophilic visceratonia Newcastle Disease
Poison.Chicken section animal, which can all suffer from, suffers from this disease.Family chicken is most susceptible, and chick is higher than Adult Chicken neurological susceptibility.It is 44 DEG C reachable, down in spirits,
Loose random is in lethargic sleep shape.Hat and wattle kermesinus or black purple.Crop speak in a low voice it is interior often hydraulically full and gas, expiratory dyspnea, throat
Issue cackle；Excrement is thin, stench, general death in 2~5 days.Subacute or chronic type symptom is similar to acute, only the state of an illness
It is relatively light, there are nervous symptoms, leg, wing paralysis, ataxia, head is bent etc. to layback or to one side, the course of disease up to 1~2 month,
It is most final dead
It is a kind of important controlling mode using Chinese herb on the prevention or treatment chicken respiratory tract disease, but it is existing for improving chicken
The Chinese herbal feed additive of disease resistance it is different degrees of have the defects that curative effect is not definite enough, safety is bad, have much room for improvement.
Summary of the invention
A kind of Chinese medicine for being to provide raising chicken disease resistance curative for effect, safety is good of the main object of the present invention is raised
Feed additives；
The second object of the present invention is to provide a kind of side for preparing the raising chicken disease resistance Chinese herbal feed additive
Method.
Above-mentioned purpose of the invention is achieved through the following technical solutions：
A kind of Chinese herbal feed additive improving chicken disease resistance, is made of following bulk pharmaceutical chemicals：Root of kirilow rhodiola, folium isatidis,
Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, oyster shell powder and Radix Glycyrrhizae.
Preferably, the parts by weight of each component are：30-35 parts of root of kirilow rhodiola, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, thorn five
Add 12-18 parts, 6-10 parts of Shitake Mushroom P.E, 6-10 parts of oyster shell powder, 2-5 parts of Radix Glycyrrhizae.
It is furthermore preferred that the parts by weight of each component are：32 parts of root of kirilow rhodiola, 25 parts of folium isatidis, 16 parts of Radix Angelicae Sinensis, 15 parts of wilsonii,
8 parts of Shitake Mushroom P.E, 6 parts of oyster shell powder, 4 parts of Radix Glycyrrhizae.
The present invention is by further test discovery, " root of kirilow rhodiola, folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, male
Increase " viola mandshurica and mulberry leaf " this two tastes bulk pharmaceutical chemicals, promotion egg that can be extremely significant on the basis of the formula of oyster shells and Radix Glycyrrhizae "
The disease resistance of chicken.
The present invention also provides a kind of Chinese herbal feed additives for improving chicken disease resistance as a result, by following bulk pharmaceutical chemicals
It is made：Root of kirilow rhodiola, folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, viola mandshurica, mulberry leaf, oyster shell powder and Radix Glycyrrhizae.
Preferably, the parts by weight of each bulk pharmaceutical chemicals are：30-35 parts of root of kirilow rhodiola, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, thorn
12-18 parts of slender acanthopanax, 6-10 parts of Shitake Mushroom P.E, 6-10 parts of viola mandshurica, 6-10 parts of mulberry leaf, 6-10 parts of oyster shell powder, Radix Glycyrrhizae 2-5
Part.
It is furthermore preferred that the parts by weight of each bulk pharmaceutical chemicals are：32 parts of root of kirilow rhodiola, 25 parts of folium isatidis, 16 parts of Radix Angelicae Sinensis, wilsonii 15
Part, 8 parts of Shitake Mushroom P.E, 7 parts of viola mandshurica, 7 parts of mulberry leaf, 6 parts of oyster shell powder, 4 parts of Radix Glycyrrhizae.
Also a kind of Chinese herbal feed additive for improving chicken disease resistance of the present invention, is made of following bulk pharmaceutical chemicals：Root of kirilow rhodiola,
Folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, viola mandshurica, mulberry leaf, oyster shell powder, Radix Isatidis, Herba portulacae, cordate houttuynia, Pu
Public English, Radix Codonopsis and Radix Glycyrrhizae；
Preferably, the parts by weight of each bulk pharmaceutical chemicals are：30-35 parts of root of kirilow rhodiola, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, thorn
12-18 parts of slender acanthopanax, 6-10 parts of Shitake Mushroom P.E, 6-10 parts of viola mandshurica, 6-10 parts of mulberry leaf, 6-10 parts of oyster shell powder, Radix Isatidis
6-10 parts, 6-10 parts of Herba portulacae, 6-10 parts of cordate houttuynia, 6-10 parts of dandelion, 6-10 parts of Radix Codonopsis, 2-5 parts of Radix Glycyrrhizae；
Most preferably, the parts by weight of each bulk pharmaceutical chemicals are：32 parts of root of kirilow rhodiola, 25 parts of folium isatidis, 16 parts of Radix Angelicae Sinensis, wilsonii 15
Part, 8 parts of Shitake Mushroom P.E, 7 parts of viola mandshurica, 7 parts of mulberry leaf, 6 parts of oyster shell powder, 7 parts of Radix Isatidis, 7 parts of Herba portulacae, cordate houttuynia 7
Part, 7 parts of dandelion, 6 parts of Radix Codonopsis, 4 parts of Radix Glycyrrhizae
Root of kirilow rhodiola (scientific name：Rhodiola rosea L.), alias：Rhodiola rosea sweeps sieve Ma boolean (hiding name) etc.；Have
The effect of tonifying Qi clearing lung-heat, intelligence development nourishing heart, controlling of bleeding with astringents, eliminating stasis to subdue swelling.Cure mainly deficiency of vital energy and physically weak, after being ill chilly, shortness of breath and fatigue, lung heat
Cough, hemoptysis, leukorrhea diarrhea, traumatic injury etc..
Folium isatidis：With clearing heat and detoxicating, the effect of blood cooling and ecchymoses removing.It cures mainly：Hot spot, erysipelas, abscess of throat, dispute are raw
The diseases such as sore, sore and toxic.
Radix Angelicae Sinensis：It enriches blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturizing dryness and lubricating intestine.The main all cards of the deficiency of blood；Irregular menstruation；Menostasis；Dysmenorrhea；Abdominal mass knot
It is poly-；Metrorrhagia and metrostaxis；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness；Intestines are dry and shit is difficult；Weight after dysentery with bloody stool；Ulcer sores；Injury from falling down,
Wilsonii：It is warm-natured, acrid flavour, slight bitter.ReturnThe spleen channel、Kidney channel、The heart channel of Hang-Shaoyin.There is the effect of replenishing qi to invigorate the spleen, tonifying the kidney to relieve mental strain.
Mushroom：Also known as flower mushroom, mushroom, fragrant letter, fragrant bacterium, dried mushroom, fragrant wild rice, it is the fructification of Pleurotaceae plant mushroom.Mushroom
It is mild-natured rich in vitamin B complex, iron, potassium, provitamin D (changing into vitamin D after solarization), sweet in flavor.Appetite stimulator is cured mainly, it is few
Gas is out of strength.
Heretofore described Shitake Mushroom P.E can be to be extracted by various extraction means (be extracted with water or with ethyl alcohol)
Extract obtained by mushroom can also be and extract obtained extract after mushroom undergoes microbial fermentation again；Wherein, institute
The Shitake Mushroom P.E stated contains certain lentinan, such as can be the lentinan containing 1% or more；Used in the present invention
Shitake Mushroom P.E can be commercially available from market, as long as can be suitably used for the present invention containing certain lentinan.
Viola mandshurica (scientific name：Viola philippica), alias open country violet, light valve violet etc..Perennial herb belongs to side
Film placenta mesh, Violaceae perennial herb, taste bitter, acrid, cold.Converge to heart and liver channels.With clearing heat and detoxicating, cool blood detumescence, clearing heat and promoting diuresis
Effect, cure mainly furunculosis, carbuncle swells, scrofula, jaundice, dysentery, diarrhea, hot eyes, sore throat, venomous snake bite.
Mulberry leaf：There is clearing away the lungheat and moisturizing, cough-relieving, reduces phlegm and internal heat, resolving sputum, controls night sweat；Tonifying liver clears liver and improve vision, treats dizzy, mistake
It sleeps, eliminate eye strain；Reduce swelling, purify the blood and ' treat dysentery, abdominal pain, weight-reducing, remove tinea pedis, the large and small intestines of benefit；Resisting stress, cool blood, drop
Blood pressure, reducing blood lipid, prevention myocardial infarction, cerebral hemorrhage, headache of dispelling, long hair；Hypoglycemic, anti-sugared disease etc..
Radix Isatidis：Hardship is trembled with fear.With clearing heat and detoxicating, the effect of cool blood relieving sore-throat.It is usually used in poison when warm epidemic disease, pharyngalgia of generating heat, epidemic heat syndrome
Macular eruption, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle swells.
Purslane has clearing heat and promoting diuresis, removing toxicity for detumescence, anti-inflammatory, quenches the thirst, diuresis and other effects.
Cordate houttuynia：Acrid flavour, it is cold, it is distributed in lung channel.It can clearing heat and detoxicating, detumescence treatment sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach invigorating
It helps digestion, is pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from real heat, heat toxin, damp evil, disease heat is controlled.
Dandelion：It is clearing heat and detoxicating, diuresis dissipating bind.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctiva
Inflammation, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections
Radix Codonopsis：Property sweet and neutral.Tonifying middle-Jiao and Qi, stomach function regulating are promoted the production of body fluid, expelling phlegm and arresting coughing.For spleen eating less loose stool, weakness of limbs, the heart
Throb with fear, shortness of breath, dry, spontaneous perspiration, rectal prolapse, the prolapse of uterus.
Another object of the present invention is to provide a kind of method for preparing the Chinese herbal feed additive, including：
(1) each bulk pharmaceutical chemicals are weighed according to the consumption proportion；
(2) by each component grinding and sieving, be uniformly mixed to get.
Wherein, in step (2), it is preferred that each bulk pharmaceutical chemicals are smashed it through 100-300 mesh, are uniformly mixed.
The present invention also provides a kind of methods for preparing the Chinese herbal feed additive, including：
(1) it is decocted, decoction liquor is filtered, filtrate is concentrated to get clear cream with water after mixing each bulk pharmaceutical chemicals；(2) second is added
Alcohol is stood, and supernatant recycles ethyl alcohol to no alcohol taste, addition aqua sterilisa to get.
Wherein, decoction number described in step (1) can be 1-3 times, and 3-8 times of water is added every time and is decocted；Step
Suddenly (2) addition ethyl alcohol to alcohol content reaches 60%.
As reference, a kind of application method of Chinese herbal feed additive of the present invention：
Chinese herbal feed additive of the present invention is incorporated into the daily ration of chicken；It incite somebody to action this according to mass percent meter as reference
Invention Chinese herbal feed additive is incorporated into the daily ration of chicken according to the ratio of 0.5-1.5%, guarantees that every chicken daily intakes 0.3-
The daily ration for being mixed with Chinese herbal feed additive is freely eaten 1g Chinese herbal feed additive by chicken.
It, can according to the test result of premunition as it can be seen that after Chinese herbal feed additive of the present invention is incorporated into the daily ration of chicken
It is effective to improve chicken for the resistance of newcastle disease, wherein compared to other test groups, disease resisting effect is bright for 1 group of test
It is aobvious to be better than other test groups；This explanation, " root of kirilow rhodiola, folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, oyster shell powder and
Increase " viola mandshurica and mulberry leaf " this two tastes bulk pharmaceutical chemicals on the basis of the formula of Radix Glycyrrhizae ", the premunition of promotion chicken that can be extremely significant.
During using Chinese herbal feed additive of the present invention, chicken is not observed and any adverse reaction occurs, illustrates in the present invention
Medicine feed addictive has good safety for chicken.
Specific embodiment
Further describe the present invention below in conjunction with specific embodiment, the advantages and features of the present invention will be with description and
It is apparent.But examples are merely exemplary for these, and it is not intended to limit the scope of the present invention in any way.Those skilled in the art
Member it should be understood that can modify without departing from the spirit and scope of the invention to details and form of the invention or
Replacement, but these modifications and replacement are fallen within the protection scope of the present invention.
The preparation of 1 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 2 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 30, folium isatidis 20, Radix Angelicae Sinensis 12, wilsonii 12, perfume
Mushroom extract 6, oyster shell powder 6, Radix Glycyrrhizae 2；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 3 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 35, folium isatidis 28, Radix Angelicae Sinensis 18, wilsonii 18, perfume
Mushroom extract 10, oyster shell powder 10, Radix Glycyrrhizae 5；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 4 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, viola mandshurica 7, mulberry leaf 7, oyster shell powder 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 5 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 30, folium isatidis 20, Radix Angelicae Sinensis 12, wilsonii 12, perfume
Mushroom extract 6, viola mandshurica 6, mulberry leaf 6, oyster shell powder 6, Radix Glycyrrhizae 2；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 6 Chinese herbal feed additive of embodiment
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 35, folium isatidis 28, Radix Angelicae Sinensis 18, wilsonii 18, perfume
Mushroom extract 10, viola mandshurica 10, mulberry leaf 10, oyster shell powder 10, Radix Glycyrrhizae 5；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 1 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, honeysuckle 6, dandelion 6, oyster shell powder 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 2 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, Fructus Forsythiae 6, wild chrysanthemum 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 3 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, Radix Isatidis 6, honeysuckle 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 4 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, dandelion 6, Radix Isatidis 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 5 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, cordate houttuynia 6, Herba portulacae 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 6 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, cordate houttuynia 6, peppermint 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 7 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, Herba portulacae 6, peppermint 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 8 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, mulberry leaf 6, cordate houttuynia 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 9 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, mulberry leaf 6, Herba portulacae 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The preparation of 10 Chinese herbal feed additive of comparative example
Each component (unit is weighed according to following weight：Kg)：Root of kirilow rhodiola 32, folium isatidis 25, Radix Angelicae Sinensis 16, wilsonii 15, perfume
Mushroom extract 8, oyster shell powder 6, mulberry leaf 6, peppermint 6, Radix Glycyrrhizae 4；
Above-mentioned each component be crushed into 100 mesh shaking screens, mix to get.
The Chinese herbal feed additive of the present invention of test example 1 improves the application effect test of laying hen disease resistance
650 health, age in days and the almost the same laying hen of weight are randomly divided into 13 groups, every group 50, i.e.,：Test 1
Group tests 2 groups, tests 3 groups, tests 4 groups, tests 5 groups, tests 6 groups, tests 7 groups, tests 8 groups, tests 9 groups, tests 10 groups,
11 groups are tested, tests 12 groups, every group 50；The daily ration for testing 1-12 group is all the same, wherein the daily ration of 1 group of test, which mixes, to be implemented
Chinese herbal feed additive prepared by example 1 (according to mass ratio, 0.5%), is tested in 2 groups of daily ration incorporation preparations of embodiment 4 by incorporation
Medicine feed addictive (according to mass ratio, 0.5%), test Chinese medicine fodder prepared by 3 groups of daily ration incorporation comparative examples 1 and add by incorporation
Adding agent, (according to mass ratio, 0.5%) incorporation, is tested Chinese herbal feed additive prepared by 4 groups of daily ration incorporation comparative examples 2 and (is pressed
According to mass ratio, 0.5%) incorporation, tests the Chinese herbal feed additive of 5 groups of daily ration incorporation preparations of comparative examples 3 (according to quality
Than 0.5%) incorporation, is tested Chinese herbal feed additive prepared by 6 groups of daily ration incorporation comparative examples 4 and (according to mass ratio, mixed
0.5%), test Chinese herbal feed additive prepared by 7 groups of daily rations incorporation comparative examples 5 (according to mass ratio, incorporation 0.5%),
Testing Chinese herbal feed additive prepared by 8 groups of daily ration incorporation comparative examples 6, (according to mass ratio, 0.5%) incorporation, tests 9 groups
Daily ration mixes Chinese herbal feed additive prepared by comparative example 7, and (according to mass ratio, 0.5%), 10 groups of daily rations of test are mixed for incorporation
0.5%) Chinese herbal feed additive for entering the preparation of comparative example 8 (according to mass ratio, mixes, tests 11 groups of daily rations incorporation comparisons
Chinese herbal feed additive prepared by embodiment 9 (according to mass ratio, 0.5%), tests 12 groups of daily rations and mixes comparative example by incorporation
(according to mass ratio, incorporation is 0.5%) for the Chinese herbal feed additive of 10 preparations；The Chinese herbal feed additive mixed in every group of daily ration
Dosage is identical.
13 groups are tested as control group, does not add any other ingredient in daily ration.
After testing the connection of 1-13 group feeding 7 days, toxic dose is attacked to each test group with the newcastle disease virus of 0.2ml/ only
Laying hen carries out challenge test；The morbidity quantity and The dead quantity that each group laying hen is counted after 3 days, calculate morbidity and mortality.
Statistical result is shown in Table 1.
The test result of the Chinese herbal feed additive of the present invention of table 1 raising laying hen premunition
According to test result as it can be seen that can effectively be mentioned after Chinese herbal feed additive of the present invention is incorporated into the daily ration of chicken
Morbidity and mortality of the high laying hen for newcastle disease virus；2 groups are tested compared to 1 group of test and test 3-11 group, test 2
The morbidity and mortality of group are significantly lower than other test groups；This explanation is in " root of kirilow rhodiola, folium isatidis, Radix Angelicae Sinensis, wilsonii, mushroom
Increase " viola mandshurica and mulberry leaf " this two tastes bulk pharmaceutical chemicals on the basis of the formula of extract, oyster shell powder and Radix Glycyrrhizae ", it can be extremely significant
Promotion chicken premunition.
During the whole test process, the broiler chicken for testing 1-12 group does not have any adverse reaction, this illustrates that Chinese medicine of the present invention is raised
Feed additives safety is good, without any adverse reactions.
Claims (10)
1. a kind of Chinese herbal feed additive for improving chicken disease resistance, which is characterized in that be made of following bulk pharmaceutical chemicals：Root of kirilow rhodiola,
Folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, oyster shell powder and Radix Glycyrrhizae.
2. Chinese herbal feed additive described in accordance with the claim 1, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Root of kirilow rhodiola
30-35 parts, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, 12-18 parts of wilsonii, 6-10 parts of Shitake Mushroom P.E, oyster shell powder 6-
10 parts, 2-5 parts of Radix Glycyrrhizae.
3. Chinese herbal feed additive according to claim 2, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Root of kirilow rhodiola
32 parts, 25 parts of folium isatidis, 16 parts of Radix Angelicae Sinensis, 15 parts of wilsonii, 8 parts of Shitake Mushroom P.E, 6 parts of oyster shell powder, 4 parts of Radix Glycyrrhizae.
4. a kind of Chinese herbal feed additive for improving chicken disease resistance, which is characterized in that be made of following bulk pharmaceutical chemicals：Red scape
It, folium isatidis, Radix Angelicae Sinensis, wilsonii, Shitake Mushroom P.E, viola mandshurica, mulberry leaf, oyster shell powder and Radix Glycyrrhizae.
5. Chinese herbal feed additive according to claim 4, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Root of kirilow rhodiola
30-35 parts, 20-28 parts of folium isatidis, 12--18 parts of Radix Angelicae Sinensis, 12-18 parts of wilsonii, 6-10 parts of Shitake Mushroom P.E, viola mandshurica 6-
10 parts, 6-10 parts of mulberry leaf, 6-10 parts of oyster shell powder, 2-5 parts of Radix Glycyrrhizae.
6. Chinese herbal feed additive according to claim 5, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Preferably,
The parts by weight of each component are：It is 32 parts of root of kirilow rhodiola, 25 parts of folium isatidis, 16 parts of Radix Angelicae Sinensis, 15 parts of wilsonii, 8 parts of Shitake Mushroom P.E, pale reddish brown
7 parts of Chinese violet, 7 parts of mulberry leaf, 6 parts of oyster shell powder, 4 parts of Radix Glycyrrhizae.
7. according to Chinese herbal feed additive described in claim 1 or 4, which is characterized in that also contain Radix Isatidis, Herba portulacae, fish
Raw meat grass, dandelion and Radix Codonopsis.
8. Chinese herbal feed additive according to claim 7, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Radix Isatidis
6-10 parts, 6-10 parts of Herba portulacae, 6-10 parts of cordate houttuynia, 6-10 parts of dandelion, 6-10 parts of Radix Codonopsis；Preferably, the weight of each component
Part it is：7 parts of Radix Isatidis, 7 parts of Herba portulacae, 7 parts of cordate houttuynia, 7 parts of dandelion, 6 parts of Radix Codonopsis.
9. a kind of method for preparing any one of claim 1-8 Chinese herbal feed additive, which is characterized in that including：
(1) each bulk pharmaceutical chemicals are weighed according to the consumption proportion；
(2) by each component grinding and sieving, be uniformly mixed to get；
Or：(1) it is decocted, decoction liquor is filtered, filtrate is concentrated to get clear cream with water after mixing each bulk pharmaceutical chemicals；(2) second is added
Alcohol is stood, and supernatant recycles ethyl alcohol to no alcohol taste, addition aqua sterilisa to get.
10. use of any one of the claim 1-8 Chinese herbal feed additive in the drug that preparation improves chicken disease resistance
On the way.
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| CN111772057A (en) * | 2020-07-23 | 2020-10-16 | 内江师范学院 | Natural compound for improving fish anti-stress response and application thereof |
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