CN108779463B - 使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘 - Google Patents

使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘 Download PDF

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CN108779463B
CN108779463B CN201780015898.1A CN201780015898A CN108779463B CN 108779463 B CN108779463 B CN 108779463B CN 201780015898 A CN201780015898 A CN 201780015898A CN 108779463 B CN108779463 B CN 108779463B
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rna complex
asirna
rna
antisense strand
pharmaceutical composition
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CN108779463A (zh
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D·K·李
S·W·弘
H·李
D·于
J·严
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Olix Pharmaceuticals Inc
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CN201780015898.1A 2016-02-02 2017-02-01 使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘 Active CN108779463B (zh)

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US201662290298P 2016-02-02 2016-02-02
US62/290,298 2016-02-02
PCT/IB2017/000166 WO2017134525A1 (en) 2016-02-02 2017-02-01 TREATMENT OF ATOPIC DERMATITIS AND ASTHMA USING RNA COMPLEXES THAT TARGET lL4Rα, TRPA1, OR F2RL1

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CN108779463A CN108779463A (zh) 2018-11-09
CN108779463B true CN108779463B (zh) 2022-05-24

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EP (1) EP3411480B1 (enExample)
JP (1) JP6944942B2 (enExample)
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CN (1) CN108779463B (enExample)
CA (1) CA3022874A1 (enExample)
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CN103328633B (zh) 2010-10-22 2018-07-10 成均馆大学校产学协力团 诱导rna干扰的核酸分子及其用途
CN108148838B (zh) 2012-05-22 2026-07-31 奥利克斯医药有限公司 具有细胞内穿透能力的诱导rna干扰的核酸分子及用途
JP7027311B2 (ja) 2015-11-16 2022-03-01 オリックス ファーマシューティカルズ，インコーポレーテッド ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療
WO2017134525A1 (en) 2016-02-02 2017-08-10 Olix Pharmaceuticals, Inc. TREATMENT OF ATOPIC DERMATITIS AND ASTHMA USING RNA COMPLEXES THAT TARGET lL4Rα, TRPA1, OR F2RL1
KR102825945B1 (ko) 2016-02-02 2025-06-30 올릭스 주식회사 Angpt2 및 pdgfb를 표적화하는 rna 복합체를 사용하는 혈관신생 관련 질환의 치료
JP7049262B2 (ja) 2016-04-11 2022-04-06 オリックス ファーマシューティカルズ，インコーポレーテッド 結合組織成長因子を標的とするｒｎａ複合体を用いた特発性肺胞線維症の治療
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
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KR102460545B1 (ko) 2020-02-18 2022-10-31 주식회사 피코엔텍 신규한 돌연변이 효모를 함유하는 천식 억제용 조성물
KR102421750B1 (ko) 2020-05-26 2022-07-19 올릭스 주식회사 MyD88을 표적으로 하는 RNAi 제제 및 이의 용도
CN114657133A (zh) * 2020-12-22 2022-06-24 未来智人再生医学研究院(广州)有限公司 一种表达靶向IL-4 Rα的shRNA和/或shRNA-miR的多能干细胞

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