CN108743780A - A kind of vulva conditioning liquid and preparation method thereof containing plant extracts - Google Patents

A kind of vulva conditioning liquid and preparation method thereof containing plant extracts Download PDF

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Publication number
CN108743780A
CN108743780A CN201810967951.4A CN201810967951A CN108743780A CN 108743780 A CN108743780 A CN 108743780A CN 201810967951 A CN201810967951 A CN 201810967951A CN 108743780 A CN108743780 A CN 108743780A
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vulva
plant extracts
conditioning liquid
containing plant
liquid containing
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Pending
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CN201810967951.4A
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Chinese (zh)
Inventor
吴晓娟
杨维
罗海浪
徐丽君
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Zhejiang Inotai Medical Devices Co., Ltd.
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Hangzhou Young Cell Biotechnology Co Ltd
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Priority to CN201810967951.4A priority Critical patent/CN108743780A/en
Publication of CN108743780A publication Critical patent/CN108743780A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of vulva conditioning liquid and preparation method thereof containing plant extracts, is made of the raw material of following weight percent:Polysaccharide 0.5%-10%, protein 0.5%-3%, plant extracts 10%-20%, antioxidant 1%-5%, moisturizer 5%-15%, thickener 0.02%-0.4%, antiseptic 0.01%-0.1%, preservative 0.05%-0.5%, surplus are purified water.The present invention, which has, to nourish, activates vagina tissue cell, make the effect that vulva is fair and tender, and restore and keep the natural elasticity of vagina tissue, delaying female vaginal cell aging, and property is mildly safe and non-stimulating, health environment-friendly, without cleaning, easy to carry, manufacture craft is simple, while having good anti-inflammatory, bacteria resistance function.

Description

A kind of vulva conditioning liquid and preparation method thereof containing plant extracts
Technical field
The present invention relates to feminine care products technical field more particularly to a kind of vulva nursing containing plant extracts Liquid and preparation method thereof.
Background technology
Women with age fade by the gradual aging of reproductive system, ovarian function, decrease in estrogen, vagina The degenerations variation such as dry and astringent, thinning and relaxation occurs for mucous membrane.Simultaneously because the color of the big nymphae of a variety of causes obscure can also become It is deep to black:(1)Inherent cause:Different ethnic groups and different personal phenotypes, including the colour of skin essence that body is presented is by body Interior DNA is determined and control, some man days life colour of skin is more black, its corresponding big nymphae is also in deeper color.(2)After sexal maturity with Time elapses melanin deposition, this is most important reason, and the direct factor that tissue color deepens blackening is exactly melanin pigmentation, And estrogen can accelerate secretion and the deposition of melanin, such as estrogen level is substantially increased in body when pregnancy, corresponding size The color of labia also can quickly deepen, excessive additionally, due to job and life stress, and endocrine disorder estrogen level is out of control, also can Accelerate the deposition of melanin.Under normal circumstances with the periodic cycle of internal estrogen, melanin is gradual on big nymphae Deposition, therefore Time fleets past women local organization color is slowly obscure pitch black.(3)The stimulation of gynecological disease also results in labia color Black, if melanin can be further aggravated in vagina tissue position calmness by reusing some drugs or product excitatory.
Currently, gynaecologic vaginal care product in the market is numerous, but stress anti-inflammatory, bacteriostasis efficacy mostly, almost to vagina There is no nourishing effect, does not have substantially especially for the product of activation, fair and tender vulva.
Invention content
The present invention is to provide a kind of vulva conditioning liquid and its system containing plant extracts to solve above-mentioned deficiency Preparation Method, can effectively fair and tender vulva, activation vagina tissue cell, recovery and keep vagina tissue natural elasticity and efficiently, The aging of delaying female vaginal cell and mild safety.
The above-mentioned purpose of the present invention is realized by technical solution below:A kind of vulva shield containing plant extracts Liquid is managed, is made of the raw material of following weight percent:Polysaccharide 0.5%-10%, protein 0.5%-3%, plant extracts 10%-20%, Antioxidant 1%-5%, moisturizer 5%-15%, thickener 0.02%-0.4%, antiseptic 0.01%-0.1%, preservative 0.05%- 0.5%, surplus is purified water.
Further:
The polysaccharide is hydroxypropyl cyclodextrin.The bonding force of hydroxypropyl cyclodextrin makes tissue mucosa generate specific surface machinery change The elastic film of shape, formation can generate smoothing effect, the corneocyte edge of some curlings can be clung, instantaneous to alleviate The tissue texture of coarse scale, while water loss can be prevented, cutin-softening layer increases skin hydration effect indirectly.
The protein is selected from one or more of collagen, Hydrolyzed Collagen, gelatin hydrolysate.
The plant extracts is carried by comprising Honegsukle flower P.E 0.1%-0.5%, hamamelis extract 4%-8%, chamomile Take object 4%-8%, glutinous rehmannia extract 0.5%-3%, extract solution from aloe 0.5%-3% and pot marigold extract 1%-5%, the above percentage equal Weight percent based on total raw material.
Honegsukle flower P.E main ingredient is chlorogenic acid, contains volatile oil, cumarin, glycosides displayed, lactone and tannin and perfume (or spice) Taste can play maximum degradation within the unit interval to harmful substance and different smell.To staphylococcus aureus, large intestine bar Bacterium, Pseudomonas aeruginosa, fungi etc. have very strong fungistatic effect, and can protect skin.
Camomile extract has anti-aging reparation damaging cells, promotes cell Proliferation and regeneration, strengthens tissue and increases Strong tissue elasticity;Leucocyte, enhancing immunocompetence can be stimulated;Moist skin is not mildly stimulated, while can nourish body surface hair;Separately One important function is to releive, and alleviates inflammation and pain symptom, has effects that tissue purification and maintenance.
Aloe extract contains grape acid, sweet sugared dew, vitamin, minerals, reed Cai glucoside, isobarbaloin, aloe-emodin Isoreactivity ingredient, the effect for playing nourishing and moisturizing, desalinating melanin and preventing melanin from generating, active cell vigor delay skin Skin aging, have make skin contraction, softness, moisturizing, inhibiting bacteria and diminishing inflammation, bleaching performance.
Pot marigold extract is rich in multivitamin, especially vitamin A and vitamin C, can prevent pigementation, powder Tender private parts tissue promotes color and luster, and delaying senility avoids organizational slack from following the string;There is contained glucide degree stimulation to cause Melanin deposition;Has the function of antibacterial anti-inflammatory.Stimulation is immune, enhancing immune system effect;Hormone can be adjusted, balance is female Hormone.
Hamamelis extract has the effect of releiving, restrain, antibacterial and sterilization.
Glutinous rehmannia extract contains mannitol, sucrose, amino acid, iridoid group and grades, and having improves blood circulation, improves The effect of skin is low and deep, nourishing yin and supplementing blood.
The antioxidant is vitamin C and/or its derivative.
The moisturizer is one or more in glycerine, propylene glycol, butanediol, pentanediol.
The thickener is selected from xanthans, dehydroxanthan, methylcellulose, carboxymethyl cellulose, ethyl cellulose, hydroxyl It is one or more in ethyl cellulose, hydroxypropyl methyl cellulose, hydroxypropyl cellulose.
The antiseptic is chlorhexidine acetate and/or poly hexamethylene biguanide.
The preservative is one or more in outstanding horse BP, decoyl hydroximic acid, Phenoxyethanol and Sensiva SC50.
The preparation method of the vulva for the containing plant extracts conditioning liquid is:
Include the following steps:
1)Appropriate purified water is added in retort;
2)Moisturizer, thickener are mixed evenly under room temperature, are added in retort, stirring extremely dissolving under the conditions of 50-80 DEG C;
2)Protein is added in retort, is stirred evenly in 50-80 DEG C of stirred in water bath to dissolving with appropriate purified water;
3)By the near room temperature of liquid in retort, plant extracts, polysaccharide, antioxidant, antiseptic, anti-corrosion are then sequentially added Agent, stirring are uniformly mixed to being completely dissolved, and are stood after defoaming up to gynaecology's vulva conditioning liquid.
A kind of vulva conditioning liquid and preparation method thereof containing plant extracts according to the present invention, have nourish, Vagina tissue cell is activated, makes the effect that vulva is fair and tender, and restore and keep the natural elasticity of vagina tissue, delaying female is cloudy Road cell ageing, and property is mildly safe and non-stimulating, health environment-friendly, and without cleaning, easy to carry, manufacture craft is simple, together When have good anti-inflammatory, bacteria resistance function.
Specific implementation mode
The present invention is described in further detail with reference to embodiment.
Embodiment 1
A kind of vulva conditioning liquid and preparation method thereof containing plant extracts, is made of the raw material of following weight percent: Hydroxypropyl cyclodextrin 8%, collagen 1%, plant extracts 14%(Honegsukle flower P.E 0.5%, hamamelis extract 4%, ocean are sweet Chrysanthemum extract 4%, glutinous rehmannia extract 3%, extract solution from aloe 0.5%, pot marigold extract 2%), 3-O- ethylascorbyls 1%, protect Humectant 15%(Glycerine 10%, propylene glycol 5%), ethyl cellulose 0.1%, chlorhexidine acetate 0.1%, Phenoxyethanol 0.1%, surplus is Purified water.
The preparation method of the vulva conditioning liquid containing plant extracts of the present embodiment is as follows:It is added in retort suitable Measure purified water;Glycerine, propylene glycol, ethyl cellulose are mixed evenly under room temperature, is added in retort, is stirred under the conditions of 50 DEG C It mixes to dissolving;Collagen is added in retort, is stirred evenly in 50 DEG C of stirred in water bath to dissolving with appropriate purified water; By the near room temperature of liquid in retort, plant extracts, polysaccharide, antioxidant, antiseptic, preservative are then sequentially added, is stirred It mixes to being completely dissolved, is uniformly mixed, stand after defoaming up to required gynaecology's vulva conditioning liquid.
The nursing film being prepared with conditioning liquid by the above-mentioned vulva containing plant extracts of the present embodiment, by following Method is made:Gynaecology's vulva conditioning liquid of preparation is filling to bottle or bag, then sterile non-woven fabrics is immersed in bottle or bag Gynaecology's vulva conditioning liquid in, finally bottle or bag are sealed.
The sterile non-woven fabrics can also use natural cotton facial mask material, silk mask material, tencel facial mask material, water-setting glue surface Membrane material or Biofibre facial mask material substitute.
Embodiment 2
A kind of vulva conditioning liquid containing plant extracts, is made of the raw material of following weight percent:Hydroxypropyl cyclodextrin 1%, Hydrolyzed Collagen 3%, plant extracts 17%(Honegsukle flower P.E 0.5%, hamamelis extract 6%, camomile extract 3%, glutinous rehmannia extract 3.5%, extract solution from aloe 1%, pot marigold extract 3%), vitamin C 3%, moisturizer 9%(Glycerine 4%, penta Glycol 5%), hydroxyethyl cellulose 0.3%, poly hexamethylene biguanide 0.04%, outstanding horse BP 0.04%, surplus is purified water.
The preparation method of the vulva conditioning liquid containing plant extracts of the present embodiment is as follows:It is added in retort suitable Measure purified water;Glycerine, pentanediol, hydroxyethyl cellulose are mixed evenly under room temperature, are added in retort, under the conditions of 80 DEG C Stirring is extremely dissolved;Hydrolyzed Collagen is added in retort, stirring with appropriate purified water in 80 DEG C of stirred in water bath to dissolving Uniformly;By the near room temperature of liquid in retort, plant extracts, polysaccharide, antioxidant, antiseptic, anti-corrosion are then sequentially added Agent, stirring are uniformly mixed to being completely dissolved, and are stood after defoaming up to required gynaecology's vulva conditioning liquid.
Example the above is only the implementation of the present invention is not intended to limit the scope of the invention, every to utilize this hair Equivalent structure or equivalent flow shift made by bright specification and embodiment content, it is relevant to be applied directly or indirectly in other Technical field is included within the scope of the present invention.

Claims (10)

1. a kind of vulva conditioning liquid containing plant extracts, which is characterized in that be made of the raw material of following weight percent: Polysaccharide 0.5%-10%, protein 0.5%-3%, plant extracts 10%-20%, antioxidant 1%-5%, moisturizer 5%-15%, thickening Agent 0.02%-0.4%, antiseptic 0.01%-0.1%, preservative 0.05%-0.5%, surplus are purified water.
2. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the polysaccharide For hydroxypropyl cyclodextrin.
3. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the albumen Matter is selected from one or more of collagen, Hydrolyzed Collagen, gelatin hydrolysate.
4. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the plant Extract is carried by comprising Honegsukle flower P.E 0.1%-0.5%, hamamelis extract 4%-8%, camomile extract 4%-8%, glutinous rehmannia Object 0.5%-3%, extract solution from aloe 0.5%-3% and pot marigold extract 1%-5%, the above percentage is taken to be based on the weight of total raw material Percentage.
5. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the antioxygen Agent is vitamin C and/or its derivative.
6. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the moisturizing Agent is one or more in glycerine, propylene glycol, butanediol, pentanediol.
7. a kind of vulva conditioning liquid containing plant extracts according to claim 1, which is characterized in that the thickening Agent is selected from xanthans, dehydroxanthan, methylcellulose, carboxymethyl cellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl It is one or more in ylmethyl cellulose, hydroxypropyl cellulose.
8. the vulva conditioning liquid according to claim 1 containing plant extracts, which is characterized in that the antiseptic is Chlorhexidine acetate and/or poly hexamethylene biguanide.
9. the vulva conditioning liquid according to claim 1 containing plant extracts, which is characterized in that the preservative choosing From one or more in outstanding horse BP, decoyl hydroximic acid, Phenoxyethanol and Sensiva SC50.
10. a kind of preparation method of vulva conditioning liquid containing plant extracts according to claim 1, feature exist In including the following steps:
1)Appropriate purified water is added in retort;
2)Moisturizer, thickener are mixed evenly under room temperature, are added in retort, stirring extremely dissolving under the conditions of 50-80 DEG C;
2)Protein is added in retort, is stirred evenly in 50-80 DEG C of stirred in water bath to dissolving with appropriate purified water;
3)By the near room temperature of liquid in retort, plant extracts, polysaccharide, antioxidant, antiseptic, anti-corrosion are then sequentially added Agent, stirring are uniformly mixed to being completely dissolved, and are stood after defoaming up to gynaecology's vulva conditioning liquid.
CN201810967951.4A 2018-08-23 2018-08-23 A kind of vulva conditioning liquid and preparation method thereof containing plant extracts Pending CN108743780A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111905037A (en) * 2020-08-13 2020-11-10 广州睿森生物科技有限公司 Nursing composition, nursing product and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533762A (en) * 2003-03-31 2004-10-06 吴天祥 Bionic skin and vagine nursing liquid
CN101513525A (en) * 2008-02-19 2009-08-26 白大成 Application of collagen and pharmaceutical compositions thereof in gynecology
CN104207957A (en) * 2014-09-17 2014-12-17 深圳港品一家实业有限公司 Fibroin care solution with functions of contracting genitals and whitening, and preparation method thereof
CN105581926A (en) * 2016-02-25 2016-05-18 刘忠波 Female genitalia care solution and preparation method thereof
CN107432890A (en) * 2017-08-16 2017-12-05 青岛大师兄生物科技有限公司 PH responsive type feminine care products and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533762A (en) * 2003-03-31 2004-10-06 吴天祥 Bionic skin and vagine nursing liquid
CN101513525A (en) * 2008-02-19 2009-08-26 白大成 Application of collagen and pharmaceutical compositions thereof in gynecology
CN104207957A (en) * 2014-09-17 2014-12-17 深圳港品一家实业有限公司 Fibroin care solution with functions of contracting genitals and whitening, and preparation method thereof
CN105581926A (en) * 2016-02-25 2016-05-18 刘忠波 Female genitalia care solution and preparation method thereof
CN107432890A (en) * 2017-08-16 2017-12-05 青岛大师兄生物科技有限公司 PH responsive type feminine care products and preparation method thereof

Non-Patent Citations (1)

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Title
唯美心语: "英国众多女性的选择!戴安娜王妃推荐私处护理液,抑菌、止痒解决你的私处小尴尬!", 《唯美心语》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111905037A (en) * 2020-08-13 2020-11-10 广州睿森生物科技有限公司 Nursing composition, nursing product and preparation method thereof

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Address after: 310000 Yuhang District, Hangzhou City, Zhejiang Province, No. 2959 Yuhangtang Road, Cangqian Street, 4 buildings and 1 storey

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Address before: 310000 Room 458, Building 3, No. 1, Luting Road, Cangqian Street, Yuhang District, Hangzhou City, Zhejiang Province

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Application publication date: 20181106