CN108686078B - Traditional Chinese medicine powder for treating pressure sores - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine powder for treating pressure sores, which belongs to the technical field of application of traditional Chinese medicines and comprises raw materials of borneol, cinnabar, dragon's blood, pearl, frankincense, calomel, catechu and buffalo horn. The traditional Chinese medicine powder for treating pressure sores has the effects of clearing away heat and toxic materials, relieving swelling and pain, inhibiting bacteria, diminishing inflammation, stopping bleeding, relieving itching, removing the necrotic tissue, promoting granulation and reducing exudation of tissue fluid, and can shorten the healing time of pressure sore wounds; the invention has the advantages of few raw material types, simple preparation process, complete retention of the effective components of the raw materials, convenient use, high cure rate and no scar after healing, and is suitable for pressure sores in various periods.
Description
Technical Field
The invention relates to traditional Chinese medicine powder, in particular to traditional Chinese medicine powder for treating pressure sores, and belongs to the technical field of application of traditional Chinese medicines.
Background
Pressure sores, also known as pressure ulcers and bedsores, are caused by tissue ulceration and necrosis due to persistent ischemia, hypoxia and malnutrition caused by long-term local tissue compression. The occurrence of pressure sores can increase pain to patients, aggravate the disease conditions and prolong the course of disease. Skin pressure sores are a common problem in rehabilitation and care. According to the literature, about 6 million people die each year from pressure sore complications.
Pressure sores often occur in the depressed areas of bony prominences, such as the sacral tail, back, shoulders, elbows, heels, medial and lateral malleoli. The process can be divided into four stages according to the occurrence and development processes:
stage I: in the stage of red and moist blood stasis, which is the initial stage of pressure sore, local tissues of the body are pressed, blood circulation is disturbed, and the skin is red, swollen, hot, painful or numb, and the skin color can not be recovered to be normal after the pressure is relieved for 30 minutes.
And stage II: in the inflammatory infiltration stage, the epidermis layer, the dermis layer or both of the skin are damaged or necrosed, the pressed part is purple red, subcutaneous nodules are often formed, blisters are often formed, and the skin is very easy to break. The patient feels pain.
Stage III: in the superficial ulcer stage, the whole skin is destroyed and can be deep in subcutaneous tissue and deep tissue, the skin blister is gradually enlarged and broken, the skin sore surface of the dermis layer has yellow exudate, and the surface is covered with pus after infection, so that the superficial tissue is necrotic, ulcer is formed, and pain is aggravated.
And IV, period: in the necrotic ulcer stage, which is a severe stage of pressure sores, necrotic tissues invade into the hypodermis and muscle layers, and infection can spread to the periphery and deep part and reach the bone surface deeply. More pus, blackening necrotic tissues, increasing purulent secretion and stink, and sepsis and septicemia easily caused by bacterial blood invasion of severe patients, so that systemic infection is caused and life is threatened.
The existing medical equipment or apparatus for preventing pressure sores is generally high in manufacturing cost or needs to be matched with a professional medical bed for use, is not suitable for family popularization, is large in limitation, can only have a certain prevention effect, and once pressure sores occur, effective treatment cannot be carried out. Aiming at the aspect of pressure sore treatment, no specific medicine in the market at present can treat pressure sore, and most of the medicines are relieving treatment, such as surgical dressing, surgical operation and the like. Surgical dressings are usually coated by conventional disinfection and single antibiotics or other bactericides, but because the medicines have stronger stimulation to wound surfaces, the retention time of the antibacterial medicines on the surfaces is short, rotten and necrotic tissues cannot be removed, the growth of granulation tissues and the healing of the wound surfaces are not facilitated, the disease course is longer, the overall curative effect is not ideal, and great pain and economic burden are brought to patients and families; the surgical operation can not radically cure the affected part of the pressure sore, but brings more pain to the patient.
The traditional Chinese medicine is a traditional Chinese medicine, and is a specific medicine of the traditional Chinese medicine. The traditional Chinese medicines for treating pressure sores are various, but the defects of complicated raw material types, high cost caused by using rare medicinal materials, complicated processing technology, more loss of effective components, incapability of being suitable for pressure sores in various periods and the like still exist.
Patent document CN103893557A discloses a traditional Chinese medicine preparation for treating bedsore, which has more than 18 kinds of raw materials and various varieties, and has a cure rate of only 70% for pressure sore patients of more than stage ii, and a lower cure rate; patent document CN105412447A discloses a pharmaceutical composition for treating stage ii pressure sores, which is prepared from 10 kinds of traditional Chinese medicine components, and the pharmaceutical composition is used after being mixed with water, white spirit, tea, egg white and the like, so that the use is inconvenient.
Disclosure of Invention
The technical problem to be solved by the invention is to provide the traditional Chinese medicine powder for treating pressure sores, which is suitable for treating pressure sores in various periods, simplifies the types of raw materials and the preparation process, and improves the cure rate.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a Chinese medicinal powder for treating pressure sore is prepared from Borneolum, Cinnabaris, sanguis Draxonis, Margarita, Olibanum, Calomelas, Catechu and cornu Bubali.
The technical scheme of the invention is further improved as follows: the weight parts of the raw materials are 1-15 parts of borneol, 20-40 parts of cinnabar, 40-60 parts of dragon's blood, 20-40 parts of pearl, 40-60 parts of frankincense, 1-15 parts of calomel, 1-15 parts of catechu and 1-25 parts of buffalo horn.
The technical scheme of the invention is further improved as follows: the weight parts of the raw materials are 7-10 parts of borneol, 25-35 parts of cinnabar, 45-55 parts of dragon's blood, 25-35 parts of pearl, 45-55 parts of frankincense, 7-10 parts of calomel, 7-10 parts of catechu and 10-16 parts of buffalo horn.
The technical scheme of the invention is further improved as follows: the weight parts of the raw materials are 8 parts of borneol, 30 parts of cinnabar, 50 parts of dragon's blood, 30 parts of pearl, 50 parts of frankincense, 8 parts of calomel, 8 parts of catechu and 13 parts of buffalo horn.
The technical scheme of the invention is further improved in that the preparation steps are as follows: cleaning and selecting the raw materials, respectively crushing the cleaned and selected raw materials, weighing the crushed raw materials in parts by weight, uniformly mixing, drying and subpackaging.
The technical scheme of the invention is further improved as follows: the particle size of each crushed raw material is 150-300 meshes.
The technical scheme of the invention is further improved as follows: the process of uniformly mixing comprises the steps of adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container for uniformly mixing, adding weighed cinnabar and pearl for uniformly mixing, and finally adding weighed dragon's blood and frankincense for uniformly mixing.
The technical scheme of the invention is further improved as follows: the drying is freeze drying, and the freeze drying process comprises the steps of pretreating at 0-2 ℃, and then cooling and drying; the temperature is reduced to-25 to-30 ℃ and the vacuum degree is 66 to 75Pa when the drying is carried out.
The technical scheme of the invention is further improved in that the using method comprises the following steps: the pressure sore surface is firstly debrided, and then the traditional Chinese medicine powder is smeared on the pressure sore surface.
The technical scheme of the invention is further improved as follows: the application cycle of the traditional Chinese medicine powder is that the dressing change is carried out once a day for the pressure sores in the first stage and the second stage, and the dressing change is carried out twice a day for the pressure sores in the third stage and the fourth stage.
Due to the adoption of the technical scheme, the invention has the technical progress that:
the traditional Chinese medicine powder for treating pressure sores has the effects of clearing away heat and toxic materials, relieving swelling and pain, inhibiting bacteria, diminishing inflammation, stopping bleeding, relieving itching, removing the necrotic tissue, promoting granulation and reducing exudation of tissue fluid, and can shorten the healing time of pressure sore wounds; the invention has the advantages of few raw material types, simple preparation process, complete retention of the effective components of the raw materials, convenient use, high cure rate and no scar after healing, and is suitable for pressure sores in various periods.
The invention provides a traditional Chinese medicine powder for treating pressure sores, which is prepared from eight raw materials, namely borneol, cinnabar, dragon's blood, pearl, frankincense, calomel, catechu and buffalo horn, wherein the raw materials are reasonably compatible, and are matched with one another to achieve the effects of clearing away heat and toxic materials, relieving swelling and pain, inhibiting bacteria, diminishing inflammation, stopping bleeding, relieving itching, removing necrotic tissue, promoting granulation and reducing exudation of tissue fluid.
Borneol in the traditional Chinese medicine powder is named as borneol and borneol. The borneol of the invention is a crystal obtained from the resin and the volatile oil of borneol fragrance, is almost pure dextroborneol, can play the roles of antibiosis and antiphlogosis in the traditional Chinese medicine powder of the invention, has the functions of inhibiting inflammation processes such as exudation of tissue fluid, tissue edema and the like, also has the effect of relieving pain, and has light stimulation to sensory nerves when being applied to local parts.
Cinnabar, also called cinnabar, mercurous chloride, cinnabar and red lead, is a natural ore of mercurous sulfide, and has the main component of mercurous sulfide, and can play the roles of clearing away heart-fire, relieving convulsion, calming the nerves, detoxifying, clearing heat and reducing swelling in the traditional Chinese medicine powder.
Sanguis Draxonis, and sea wax. The dragon's blood is taken from resin in fruits and rattan of daemonorops draco of palmaceae, and can play a role in dissipating blood stasis and relieving pain, resisting bacteria and stopping bleeding, and promoting tissue regeneration and healing sore in the traditional Chinese medicine powder.
The pearl is mainly produced in bodies of mollusks of pearl shellfish and nacre shellfish and is generated due to endocrine function, and the chemical components of the pearl are 91.6 percent of calcium carbonate, 4 percent of water and 4 percent of organic matters; the pearl used in the traditional Chinese medicine powder is preferably a pearl layer, various amino acids contained in the pearl layer, such as leucine, methionine, alanine, glycine, glutamic acid, aspartic acid and the like, and 30 kinds of trace elements, taurine, rich vitamins, peptides and the like contained in the pearl layer can improve the immunity of a human body and supplement calcium for the organism, and the traditional Chinese medicine powder can play a role in calming nerves, arresting convulsion, detoxifying and promoting granulation.
Frankincense, also known as Lavender incense. The frankincense used in the invention is resin exuded from bark of boswellia serrata and congeneric plants of the family Burseraceae, contains 60-70% of resin, 27-35% of gum and 3-8% of volatile oil, and has the effects of regulating qi and activating blood circulation, inhibiting bacteria and relieving pain, and removing stasis and dispelling toxin in the traditional Chinese medicine powder.
Calomel, mainly containing mercurous chloride. The natural product is named as jiangu mercury mine and is also named as calomel chemically. The calomel powder used in the invention is white, large and bright, is needle-shaped crystal, light in weight and has no mercury beads, and the traditional Chinese medicine powder can play the effects of sterilizing and diminishing swelling, removing necrotic tissue and promoting granulation, relaxing bowels and removing dampness.
The catechu used in the traditional Chinese medicine powder is dry decocted extract of peeled branches and dried branches of catechu trees of albizia plants in leguminosae, namely the catechu extract, the catechu and the black catechu, and has the effects of protecting liver and benefiting gallbladder, resisting bacteria and eliminating blood, astringing dampness and promoting granulation and healing sore in the traditional Chinese medicine powder.
Cornu Bubali is prepared from cornu Bubali with bone, hollow and medulla, and cornu Rhinocerotis is grown on skin and formed by epidermis keratinization. The buffalo horn used in the invention contains cholesterol, cardiotonic components, peptides, horn fibers, serine, glycine, alanine, lysine, histidine, aspartic acid, arginine, threonine, glutamic acid, proline, cystine, methionine, isoleucine, leucine, tyrosine, phenylalanine and other amino acids, can provide various nutrient substances for organisms, can promote the growth of new meat, and shorten the time for healing wound surfaces; the cornu bubali also has the effects of clearing away heat and toxic materials, cooling blood, stopping bleeding and reducing swelling in the traditional Chinese medicine powder, is lower in price compared with the rare traditional Chinese medicine rhinoceros horn, has the effect similar to that of the rhinoceros horn, and can reduce the cost of the traditional Chinese medicine powder.
The frankincense and the dragon's blood in the traditional Chinese medicine powder are matched with each other, so that the traditional Chinese medicine powder has stronger effects of promoting blood circulation and promoting granulation, healing sore and relaxing tendons and regulating qi and blood, and has excellent treatment effects on malignant boil, carbuncle-abscess, unhealed skin for a long time, incised wound bleeding, wound malaise and the like; the catechu and the cinnabar in the traditional Chinese medicine powder are matched with each other, so that the traditional Chinese medicine powder has stronger effects of detoxifying and healing sores, can prevent the damage to liver and kidney caused by the combination of mercury contained in the cinnabar and body protein, improves the immunity of a body, and reduces the occurrence probability of side effects; the dragon's blood, frankincense, calomel and borneol in the traditional Chinese medicine powder are matched with each other to play stronger effects of removing the necrotic tissue and promoting granulation, and reducing swelling and generating blood; the catechu, the frankincense, the borneol and the dragon's blood in the traditional Chinese medicine powder are matched with each other, so that the traditional Chinese medicine powder has stronger effects of removing stasis and eliminating dampness, and activating blood and relaxing bowels; the cornu bubali, the calomel, the catechu and the cinnabar in the traditional Chinese medicine powder are matched with each other, so that the traditional Chinese medicine powder has stronger effects of resisting bacteria, diminishing inflammation, healing sore and promoting granulation, can promote the healing of wound surfaces and shorten the healing time; the cinnabar and borneol in the traditional Chinese medicine powder are matched with each other, so that the traditional Chinese medicine powder has stronger effects of relieving swelling, detoxifying and inhibiting regeneration of pyocutaneous diseases. The traditional Chinese medicine powder has good treatment effect on pressure sores in various periods, the cure rate reaches over 90 percent, and scars are basically not left after healing, and relapse is avoided. In addition, the traditional Chinese medicine powder for treating pressure sores has mild effects, does not generate strong stimulation on wound surfaces, and does not aggravate the pain of patients; the long-term application of the medicine does not cause the damage of liver, gall bladder, kidney and the like of a patient, does not cause the drug dependence of the patient, and can provide required nutrient substances for the healing of wound surfaces and the growth of granulation, thereby shortening the healing time and improving the treatment effect.
The raw material components used by the invention are eight kinds of borneol, cinnabar, dragon's blood, pearl, frankincense, calomel, catechu and buffalo horn, and the raw material components are few in variety, easy to obtain, low in price and low in cost; the preparation process is simple, and the raw material components are only required to be pretreated by cleaning and the like, then crushed, mixed, dried and subpackaged, so that the complex steps are not required; in addition, the invention does not need any extraction and food additive, the active ingredients of the raw materials are completely reserved, the safety of the finished product is high, and the invention is suitable for treating pressure sores in each period.
According to the invention, the uniform mixing process in the preparation process of the traditional Chinese medicine powder is uniformly mixed by adopting an equivalent incremental dilution method, the raw material components with low content are firstly added into a uniform mixing container for uniform mixing, and then other raw material components with high content are added, so that the uniform stability and content uniformity of the powder are greatly improved, the fineness, color and other aspects of the powder are relatively consistent, and the excellent curative effect of the powder is ensured; in addition, the raw materials are crushed into particles with the particle size of 150-300 meshes, the traditional Chinese medicine powder meets the external requirement of the powder within the optimal particle size range, and the powder has large dispersion degree and large specific surface area, so that the contact effect of the powder and a wound surface can be increased when the powder is used for treating pressure sores, the treatment effect is improved, particularly, the moisture absorption effect is obvious, and the wound surface is kept dry and comfortable for a long time.
The preparation process of the traditional Chinese medicine powder is preferably freeze-dried during drying, and the uniformly mixed raw materials are freeze-dried, so that the active ingredients of the raw materials are completely reserved, and the loss is reduced. The method comprises the steps of pre-cooling each raw material at 0-2 ℃, then drying at-25-30 ℃ and 66-75 Pa, and compared with the conventional drying at higher temperature, the method can avoid the deterioration reaction such as the damage of thermosensitive components of the material and the oxidation of easily-oxidized components in the high-temperature drying process (for example, the borneol of the invention contains volatile components, and the loss of effective components and the reduction of drug effect are easily caused by drying at higher temperature), and the preservation rate of active substances (and effective components) of each raw material is high; secondly, precooling is carried out during freeze drying treatment, so that the components of the traditional Chinese medicine powder form a stable solid skeleton, the solid skeleton is basically inconvenient to keep after water is evaporated, the shrinkage rate is far lower than that of products dried by other methods, the appearance of the material is well kept, and the appearance quality is good; thirdly, after the traditional Chinese medicine is precooled, the internal water exists between the solid frameworks in the form of ice crystals, and substances such as inorganic salt dissolved in water are also uniformly distributed in the ice crystals and are separated out on the spot during cooling and drying, so that the phenomenon that the inorganic salt carried by the ice crystals is separated out on the surface to harden the surface of the medicinal material when the internal water of the material migrates to the surface in the general drying process is avoided; and finally, the freeze-drying method ensures that the dehydration is thorough, the weight is light, the storability is good, the long-distance transportation and storage are suitable, and the shelf life can reach 3-5 years by adopting vacuum packaging at normal temperature.
The traditional Chinese medicine powder disclosed by the invention is simple in use method and convenient to use. When the traditional Chinese medicine powder is used for treating pressure sores, firstly, debridement treatment is carried out on pressure sore surfaces, carrion is cleaned, then the traditional Chinese medicine powder is uniformly scattered on wound surfaces, a layer of sterile gauze can be used for fixing to prevent the medicine powder from falling off, and the using method is simple and has no difficulty; secondly, the medication period can be flexibly adjusted, the dressing change is carried out once a day for the pressure sores in the first stage and the second stage, the dressing change is carried out twice a day for the pressure sores in the third stage and the fourth stage, the dressing change period is longer, the action time of the medicinal powder is long, and the dressing change is not required frequently.
Detailed Description
The present invention will be described in further detail with reference to the following examples:
a traditional Chinese medicine powder for treating pressure sores comprises eight raw materials, namely 1-15 parts by weight of borneol, cinnabar, dragon's blood, pearl (preferably a pearl layer of pearl), frankincense, calomel, catechu and buffalo horn, 20-40 parts by weight of cinnabar, 40-60 parts by weight of dragon's blood, 20-40 parts by weight of pearl, 40-60 parts by weight of frankincense, 1-15 parts by weight of calomel, 1-15 parts by weight of catechu and 1-25 parts by weight of buffalo horn, wherein the preferable raw materials comprise 7-10 parts by weight of borneol, 25-35 parts by weight of cinnabar, 45-55 parts by weight of dragon's blood, 25-35 parts by weight of pearl, 45-55 parts by weight of frankincense, 7-10 parts by weight of calomel, 7-10 parts by weight of catechu and 10-16 parts by weight of buffalo horn, and the more preferable raw materials comprise 8 parts by weight of borneol, 30 parts by weight of cinnabar, 50 parts by weight of dragon's blood, 30 parts by weight of pearl, 50 parts by weight of frankincense, 8 parts by weight of calomel, 8 parts by weight of catechu and 13 parts of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain the particles with the particle size of 150-300 meshes;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. drying, preferably freeze drying, pre-freezing the uniformly mixed medicinal powder at 0-2 ℃, then cooling, and drying under the environment of-25 to-30 ℃ and 66-75 Pa of vacuum degree;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
The application method of the traditional Chinese medicine powder for treating pressure sores comprises the following steps: the pressure sore surface is debrided (alcohol, hydrogen peroxide or cold boiled water, preferably hydrogen peroxide) and then the traditional Chinese medicine powder is smeared on the pressure sore surface, and can be wrapped by sterile gauze to prevent the powder from falling off.
The application period of the traditional Chinese medicine powder for treating pressure sores can be flexibly adjusted according to the severity of the pressure sores, specifically, the medicine can be changed once a day for pressure sores in stages I and II, and twice a day for pressure sores in stages III and IV, and the times of medicine change can be increased or decreased according to actual conditions.
Example 1
A traditional Chinese medicine powder for treating pressure sores comprises eight raw materials including, by weight, 1 part of borneol, 40 parts of cinnabar, 40 parts of dragon's blood, 40 parts of pearl, 40 parts of frankincense, 15 parts of calomel, 1 part of catechu and 25 parts of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain the particle size of 150 meshes;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. freeze drying, pre-freezing the mixed powder at 0 deg.C, cooling, and drying at-25 deg.C and vacuum degree of 75 Pa;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
Example 2
A traditional Chinese medicine powder for treating pressure sores comprises eight raw materials including, by weight, 15 parts of borneol, 20 parts of cinnabar, 60 parts of dragon's blood, 20 parts of pearl, 60 parts of frankincense, 1 part of calomel, 15 parts of catechu and 1 part of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain the particle size of 300 meshes;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. freeze drying, pre-freezing the mixed powder at 2 deg.C, cooling, and drying at-30 deg.C and 66Pa vacuum degree;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
Example 3
A traditional Chinese medicine powder for treating pressure sores comprises eight raw materials including 7 parts by weight of borneol, 35 parts by weight of cinnabar, 45 parts by weight of dragon's blood, 35 parts by weight of pearl, 45 parts by weight of frankincense, 10 parts by weight of calomel, 7 parts by weight of catechu and 16 parts by weight of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain 200-mesh particles;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. freeze drying, pre-freezing the mixed powder at 1 deg.C, cooling, and drying at-27 deg.C and vacuum degree of 70 Pa;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
Example 4
A traditional Chinese medicine powder for treating pressure sores comprises eight raw materials including, by weight, 10 parts of borneol, 25 parts of cinnabar, 55 parts of dragon's blood, 25 parts of pearl, 55 parts of frankincense, 7 parts of calomel, 10 parts of catechu and 10 parts of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain the particle size of 250 meshes;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. freeze drying, pre-freezing the mixed powder at 0.5 deg.C, cooling, and drying at-28 deg.C and vacuum degree of 72 Pa;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
Example 5
A traditional Chinese medicine powder for treating pressure sores comprises eight raw materials, namely 8 parts by weight of borneol, 30 parts by weight of cinnabar, 50 parts by weight of dragon's blood, 30 parts by weight of pearl, 50 parts by weight of frankincense, 8 parts by weight of calomel, 8 parts by weight of catechu and 13 parts by weight of buffalo horn.
A preparation method of a Chinese medicinal powder for treating pressure sore comprises:
A. cleaning, removing impurities and non-medicinal components, washing Margarita with water, drying, and parching Olibanum;
B. crushing, namely crushing the cleaned raw materials respectively to obtain 225 meshes of particle size;
C. uniformly mixing, namely weighing the crushed raw materials according to parts by weight, uniformly mixing, wherein an equivalent incremental dilution method is adopted in the uniformly mixing process, namely, firstly, adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container, uniformly mixing, then adding weighed cinnabar and pearl, uniformly mixing, and finally adding weighed dragon's blood and frankincense, and uniformly mixing;
D. freeze drying, pre-freezing the mixed powder at 1 deg.C, cooling, and drying at-28 deg.C and vacuum degree of 71 Pa;
E. subpackaging, namely subpackaging the freeze-dried medicinal powder and subpackaging the medicinal powder into vacuum packaging bags or packaging bottles to obtain the traditional Chinese medicine powder for treating pressure sores.
Typical cases
Case 1
Patients who have a certain sex, male sex, age 81, the disease conditions of the patients are: when the patient lies in bed for a long time, the right hip bone position at the tail bone position is wounded due to long-term compression of subcutaneous tissues to form pressure sores, the sore surfaces are about 8 centimeters multiplied by 9 centimeters, the dermis part of the skin of the damaged area is lost, and a shallow open ulcer is formed.
The wound surface is treated by hydrogen peroxide, then the traditional Chinese medicine powder for treating pressure sores prepared in the embodiment 1 of the invention is smeared on the wound surface, the medicine is changed once a day, the surface of the wound surface scabs on the fifth day after the traditional Chinese medicine powder for treating pressure sores is used, the wound surface starts to heal on the seventh day until the wound surface heals, and no scar is left after healing.
Case 2
Patients with certain Wu and female sex, age 72 years, the disease conditions of the patients are: when the patient lies in the bed for a long time, the left hip bone position is wounded by pressing subcutaneous tissues for a long time to form pressure sores, the surface of each sore is about 3 centimeters multiplied by 5 centimeters, and the skin of the damaged area is brownish red and has pain, hard blocks and viscous exudation.
The wound surface is treated by hydrogen peroxide, then the traditional Chinese medicine powder for treating pressure sores prepared in the embodiment 3 is smeared on the wound surface, the medicine is changed once a day, the surface of the wound surface scabs the next day after the traditional Chinese medicine powder for treating pressure sores is used, the wound surface starts to heal the fourth day until the wound surface heals, and no scar is left after healing.
Case 3
The patient Song a certain number of patients, sex women, age 31 years old, the patient's condition is: when the bone cancer is bedridden, a plurality of pressure sores are formed on the body, and the wound surface is in pressure sores in stages II, III and IV.
The wound surface is treated by hydrogen peroxide, then the traditional Chinese medicine powder for treating pressure sores prepared in the embodiment 5 of the invention is coated on the wound surface, a layer of sterile gauze can be wrapped to prevent the medicine powder from falling off, the medicine is changed once every day for pressure sores in the second stage, and the medicine is changed twice every day for pressure sores in the third stage and the fourth stage, the surface of the wound surface is scabbed the second day after the traditional Chinese medicine powder for treating pressure sores is used, and the wound surface starts to heal until the wound surface heals, and no scar is left after healing.
Case 4
Patient Liu somewhere, sex woman, age 83 years old, patient's condition is: when the cerebellum is laid up for a long time, the right hip bone position is wounded by pressing subcutaneous tissues for a long time to form pressure sores, the surface of the sores is about 5cm multiplied by 7cm, the skin of the damaged area is brownish red and has pain, and hard blocks and viscous exudation.
The wound surface is treated by hydrogen peroxide, then the traditional Chinese medicine powder for treating pressure sores prepared in the embodiment 5 of the invention is smeared on the wound surface, the medicine is changed once a day, the surface of the wound surface scabs the next day after the traditional Chinese medicine powder for treating pressure sores is used, the wound surface starts to heal the fourth day until the wound surface heals, and no scar is left after healing.
Comparative test
The comparison test is to carry out clinical comparison on the traditional Chinese medicine powder for treating pressure sores and the currently common rubber tissue regeneration promoting paste for treating pressure sores, and the specific test process and results are as follows:
case data:
30 patients with pressure sores were randomized into treatment and control groups. The treatment groups were 18, 10 men and 8 women; age 31-83 years, average 55 years; the diameter of the pressure sore is 1.5-9 cm, and the average diameter is 5 cm; 5 cases in I phase, 6 cases in II phase, 4 cases in III phase and 3 cases in IV phase. 12 cases in the control group, 7 cases in the male and 5 cases in the female; age 33-80 years, average age 54 years; the diameter of the pressure sore is 1.3-8.7 cm, and the average diameter is 5.2 cm; 3 cases in I phase, 4 cases in II phase, 2 cases in III phase and 4 cases in IV phase. The two groups are statistically treated in the aspects of sex, age, disease condition and the like, have no significant difference and are comparable.
The treatment method comprises the following steps:
after the wound surfaces of 18 cases of treatment groups are disinfected conventionally, the traditional Chinese medicine powder for treating pressure sores is uniformly scattered on the wound surfaces, wrapped by a layer of sterile gauze and subjected to dressing change treatment according to dressing change cycles that the pressure sores in the first stage and the second stage are changed once a day and the pressure sores in the third stage and the fourth stage are changed twice a day; in 12 cases of the control group, after the wound surface is disinfected conventionally, the plaster is applied to the wound surface, and the dressing change period is the same as that of the traditional Chinese medicine powder for treating pressure sores. The two groups were used together for 30 days to observe the clinical effect.
The evaluation standard of curative effect is as follows:
the curative effect standard is established according to three levels of cure, effectiveness and ineffectiveness. And (3) curing: the wound surface is completely healed, and the epithelium is completely covered; the method has the following advantages: the wound surface is dry, the area is reduced, and granulation tissues grow; and (4) invalidation: the area of the wound surface is not obviously reduced or enlarged.
The treatment results are as follows:
TABLE 1
| Group of | Number of examples | Cure of disease | Is effective | Invalidation | Cure rate (%) | Total effective rate |
| Treatment group | 18 | 16 | 18 | 0 | 88.9 | 100 |
| Control group | 12 | 7 | 9 | 3 | 58.3 | 75 |
The above table shows that the cure rate and the total effective rate of the pressure sores of the patients in the treatment group are respectively 88.9 percent and 100 percent, which are obviously higher than 58.3 percent and 75 percent of those in the control group.
The wound healing time of two groups of pressure sore patients is compared:
TABLE 2
| Group of | Number of examples | Stage I (d) | Stage II (d) | Stage III (d) | Stage IV (d) |
| Treatment group | 18 | 4.5 | 7.2 | 10.2 | 13.5 |
| Control group | 12 | 6.8 | 9.7 | 17.9 | 25.8 |
From the above table, it can be seen that the treatment time of the pressure sore patients in the treatment group is significantly shorter than that in the control group.
Recurrence after healing: follow-up investigations were carried out on the patients after the treatment group and the control group, and the recurrence after 1 month, 2 months, 6 months and 1 year after the treatment was recorded, respectively, and the results are shown in the following table:
TABLE 3
| Group of | Number of examples | 1 month | 2 months old | 6 months old | 1 year |
| Treatment group | 16 | 0 | 0 | 0 | 2 |
| Control group | 7 | 0 | 1 | 3 | 5 |
As can be seen from the above table, the patients cured in the treatment group have no recurrence within the second half of the cure, only 2 patients have recurrence after 1 year, and the recurrence rate in 1 year is only 12.5%; the patients cured in the control group have relapse within 2 months after the patients are cured, and the relapse rate of 1 year is 71.4 which is obviously higher than that of the treatment group.
In conclusion, the traditional Chinese medicine powder for treating pressure sores is suitable for being used in various stages of pressure sores, has certain treatment effect on various stages, is short in wound healing time, and improves the treatment effect and the cure rate of the pressure sores; in addition, the recurrence rate of pressure sores of patients cured by the traditional Chinese medicine powder for treating pressure sores is extremely low, and the traditional Chinese medicine powder for treating pressure sores has an excellent effect of radically treating pressure sores.
Claims (6)
1. A traditional Chinese medicine powder for treating pressure sores is characterized in that: the raw materials comprise Borneolum Syntheticum, Cinnabaris, sanguis Draxonis, Margarita, Olibanum, Calomelas, Catechu and cornu Bubali,
the weight parts of the raw materials are 1-15 parts of borneol, 20-40 parts of cinnabar, 40-60 parts of dragon's blood, 20-40 parts of pearl, 40-60 parts of frankincense, 1-15 parts of calomel, 1-15 parts of catechu and 1-25 parts of buffalo horn;
cleaning and selecting the raw materials, respectively crushing the cleaned and selected raw materials, weighing the crushed raw materials in parts by weight, uniformly mixing, drying and subpackaging.
2. The traditional Chinese medicine powder for treating pressure sores according to claim 1, which is characterized in that: the weight parts of the raw materials are 7-10 parts of borneol, 25-35 parts of cinnabar, 45-55 parts of dragon's blood, 25-35 parts of pearl, 45-55 parts of frankincense, 7-10 parts of calomel, 7-10 parts of catechu and 10-16 parts of buffalo horn.
3. The traditional Chinese medicine powder for treating pressure sores as claimed in claim 2, wherein: the weight parts of the raw materials are 8 parts of borneol, 30 parts of cinnabar, 50 parts of dragon's blood, 30 parts of pearl, 50 parts of frankincense, 8 parts of calomel, 8 parts of catechu and 13 parts of buffalo horn.
4. The traditional Chinese medicine powder for treating pressure sores according to claim 1, which is characterized in that: the particle size of each crushed raw material is 150-300 meshes.
5. The traditional Chinese medicine powder for treating pressure sores according to claim 1, which is characterized in that: the process of uniformly mixing comprises the steps of adding weighed catechu, calomel, borneol and buffalo horn into a uniformly mixing container for uniformly mixing, adding weighed cinnabar and pearl for uniformly mixing, and finally adding weighed dragon's blood and frankincense for uniformly mixing.
6. The traditional Chinese medicine powder for treating pressure sores according to claim 1, which is characterized in that: the drying is freeze drying, and the freeze drying process comprises the steps of pretreating at 0-2 ℃, and then cooling and drying; the temperature is reduced to-25 to-30 ℃ and the vacuum degree is 66 to 75Pa when the drying is carried out.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101347559A (en) * | 2008-07-02 | 2009-01-21 | 刘彦宾 | Medicament for treating ulcer of skin |
| CN101417060A (en) * | 2008-11-14 | 2009-04-29 | 蔡长宇 | Plaster capable of treating trauma, traumatic injury, alopecia areata and burn and scald |
| CN102327419A (en) * | 2011-09-22 | 2012-01-25 | 辛胜会 | External use medicine for treating wound healing |
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| CN104083565A (en) * | 2014-06-20 | 2014-10-08 | 烟台华昕生物科技有限公司 | Bedsore skin-activating ointment and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101347559A (en) * | 2008-07-02 | 2009-01-21 | 刘彦宾 | Medicament for treating ulcer of skin |
| CN101417060A (en) * | 2008-11-14 | 2009-04-29 | 蔡长宇 | Plaster capable of treating trauma, traumatic injury, alopecia areata and burn and scald |
| CN102327419A (en) * | 2011-09-22 | 2012-01-25 | 辛胜会 | External use medicine for treating wound healing |
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