CN104083565A - Bedsore skin-activating ointment and application thereof - Google Patents
Bedsore skin-activating ointment and application thereof Download PDFInfo
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- CN104083565A CN104083565A CN201410280672.2A CN201410280672A CN104083565A CN 104083565 A CN104083565 A CN 104083565A CN 201410280672 A CN201410280672 A CN 201410280672A CN 104083565 A CN104083565 A CN 104083565A
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- skin
- ointment
- bedsore
- decubital ulcer
- activating
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention relates to a traditional Chinese medicine preparation, and in particular relates to a bedsore skin-activating ointment comprising the following raw materials by the mass percentage: 9-11% of borneol, 12-15% of lapidem catechumenis, 8-10% of sangusis draconis, 5.5-7% of pseudo-ginseng, 7-9% of frankincense, 12.5-14% of a pearl powder, 11-13% of vaseline, and 27-29% of safflower. The bedsore skin-activating ointment has the beneficial effects that the bedsore skin-activating ointment has an inhibitory effect on escherichia coli, staphylococcus aureus and other bacteria microorganisms, is capable of removing necrotic tissues and promoting tissue regeneration, activating blood circulation and relieving pain, enables various sores which are not healed all the year round and scabies diseases to be rapidly restored and healed in a short term, improves local microcirculation, has repairing and maintenance effects on the skin, can be used for treating bedsore, and has a better therapeutic effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of decubital ulcer skin-active ointment, belong to tcm field.
Background technology
Decubital ulcer claims again pressure ulcer, pressure ulcer, is due to the long-term pressurized of local organization, continuous ischemia, anoxia, malnutrition occur and causes tissue fester's necrosis.Pressure ulcer is the problem of a universality in rehabilitation, nursing.According to related documents, approximately there are every year 60000 people to die from pressure ulcer concomitant symptoms.
Decubital ulcer easily send out that position is multiple to be born in without muscle parcel or Musclar layer is thinner, lack the fatty tissue protection frequent bone knuckle place of pressurized again.Concrete, comprising: 1) dorsal position is apt to occur in occipital tuberosity, scapular region, elbow, vertebral body knuckle place, sacrococcygeal region, heel.2) lateral position is apt to occur in ear, acromion, ancon, rib, hip, kneed medial and lateral and, medial and lateral malleolus.3) ventricumbent position is apt to occur in ear, buccal, shoulder, female breast, male genital organ, crista iliaca, knee, toe.
Because decubital ulcer is common frdquently encountered disease, and people's Health and Living is had a significant impact, therefore the treatment of this disease is subject to people's attention.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, a kind of decubital ulcer skin-active ointment is provided, the quality percentage composition of its raw material composition and each component is as follows:
Preferably, the quality percentage composition of the raw material of described decubital ulcer skin-active ointment composition and each component is as follows:
The preparation method of decubital ulcer skin-active ointment of the present invention is as follows: after getting Borneolum Syntheticum, stone catechu, Sanguis Draxonis, Radix Notoginseng, Olibanum, Margarita powder and Flos Carthami and pulverizing, sieve, mix homogeneously obtains mixed-powder; Mixed-powder is added in vaseline, to stir to paste and obtain decubital ulcer skin-active ointment.
Preferably, the order number of aforementioned pulverizing is 100～180 orders.
The invention also discloses the application that aforementioned decubital ulcer skin-active ointment treats patients with decubitus in preparation in preparation.
The invention has the beneficial effects as follows: the bacterial micro-organism such as escherichia coli, staphylococcus aureus is had to inhibitory action, removing the necrotic tissue and promoting granulation, promoting blood circulation and stopping pain, to the skin ulcer of various long-term disunion, scabies class disease is fast quick-recovery recovery from illness in a short time, improves local microcirculation, and skin is had to the maintenance of reparation effect, can be used for the treatment of decubital ulcer, there is good therapeutic effect.
Detailed description of the invention
Below principle of the present invention and feature are described, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
After getting Borneolum Syntheticum 10g, stone catechu 14g, Sanguis Draxonis 9g, Radix Notoginseng 6g, Olibanum 8g, Margarita powder 13g and Flos Carthami 28g pulverizing, mistake 180 mesh sieves, mix homogeneously obtains mixed-powder; Mixed-powder is added in 12g vaseline and stirred to paste, obtain decubital ulcer skin-active ointment.
Embodiment 2
After getting Borneolum Syntheticum 9g, stone catechu 15g, Sanguis Draxonis 8g, Radix Notoginseng 7g, Olibanum 7g, Margarita powder 14g and Flos Carthami 29g pulverizing, mistake 120 mesh sieves, mix homogeneously obtains mixed-powder; Mixed-powder is added in 11g vaseline and stirred to paste, obtain decubital ulcer skin-active ointment.
Embodiment 3
After getting Borneolum Syntheticum 11g, stone catechu 12g, Sanguis Draxonis 10g, Radix Notoginseng 5.5g, Olibanum 9g, Margarita powder 12.5g and Flos Carthami 27g pulverizing, mistake 100 mesh sieves, mix homogeneously obtains mixed-powder; Mixed-powder is added in 13g vaseline and stirred to paste, obtain decubital ulcer skin-active ointment.
Embodiment 4 antibacterial activity tests
The antibacterial activity of the decubital ulcer skin-active ointment that employing inhibition zone method test implementation example 1-3 prepares.Get frozen tested strain (being respectively staphylococcus aureus CMCC26003 and escherichia coli CMCC44102) slant tube, the a little bacterial strain of picking under aseptic condition, draw dull and stereotyped, after 37 DEG C of cultivation 24h, be inoculated into nutrient broth NB (5mL/ test tube), soft vibration for several times, strain is melted and disperse, cultivate 24h for 37 DEG C, obtain bacteria suspension.
Draw 1mL bacteria suspension to plating medium, after painting flat board, plate is built, lie against on platform.Under aseptic condition, getting respectively decubital ulcer skin-active ointment prepared by 0.05g embodiment 1-3 smoothens in the upper surface of filter paper dick (radius 6mm), the filter paper that scribbles decubital ulcer skin-active ointment with aseptic tweezer gripping is placed in culture dish surface, the one side that scribbles ointment contacts with culture medium, 4, every ware, in 37 DEG C of incubators, be inverted and cultivate 24h, take out culture medium and measure inhibition zone size.Meanwhile, there is the filter paper dick of 0.1ml normal saline as blank to drip.
According to the method described above, respectively tested strain staphylococcus aureus CMCC26003 and escherichia coli CMCC44102 are carried out to antibiotic property test.Experimental result is as shown in table 1.
Table 1 Bactericidal test result
The antibacterial activity test result demonstration of table 1, decubital ulcer skin-active ointment has inhibitory action to escherichia coli and staphylococcus aureus.
Experimental example
1. experimental subject:
Choose patient's 60 examples of decubital ulcer occur, age 40-85 year, average 69 years old.Wherein, male 26 examples, female's 34 examples.
In above-mentioned patients with bedsore, tail sacrum portion 38 examples, hip 11 examples, back 4 examples, ankle and foot 7 examples.
2. decubital ulcer criterion
I degree: pressurized position skin rubefaction, epidermis erosion, oozes out on a small quantity.II degree: skin holostrome ulceration, but subcutaneous tissue not yet involves.III degree: skin ulceration reaches subcutaneous tissue deeply, involves fascia and muscle, but deep layer osseous tissue is not got involved.IV degree: deeply reach osseous tissue, accompany osteonecrosis and infection simultaneously.
3. efficacy assessment standard
Formulate following efficacy assessment standard with reference to " disease of tcm Standardization of diagnosis and curative effect ":
1) recovery from illness: wound surface epithelium covers completely, and cicatrix is solid, observed wound surface through 1 week and does not fester again.
2) effective: wound surface dwindles > 75%, and granulation tissue is fresh, remission.
3) take a turn for the better: wound surface dwindles > 25%, and < 75%, granulation tissue comparatively fresh, symptom is improved.
4) invalid: though wound surface is front fresh, dwindle < 25%, and granulation tissue growth seldom.
4. therapeutic scheme:
By warm water cleaning for affected part, dry, alcohol disinfecting, the decubital ulcer skin-active ointment of then patients with bedsore being smeared to embodiment 1, in affected part, every day 2-3 time, 7 days is a course for the treatment of, after 2 courses for the treatment of, adds up curative effect.
3. effect
3.1 statistical result
The statistical result treating patients with decubitus
| Total number of cases | Cure | Effective | Effectively | Invalid | Total effective rate |
| 60 examples | 55 examples | 3 examples | 1 example | 1 example | 98％ |
3.2 ointment are on the scab impact of rate of patient
Rate scabs
| Time | 5 days | 10 days | 14 days |
| Rate scabs | 23.3％ | 53.6％ | 94％ |
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (5)
1. a decubital ulcer skin-active ointment, the quality percentage composition of its raw material composition and each component is as follows:
2. decubital ulcer skin-active ointment as claimed in claim 1, is characterized in that, the raw material composition of described decubital ulcer skin-active ointment and the quality percentage composition of each component are as follows:
3. the preparation method of decubital ulcer skin-active ointment described in the arbitrary claim of claim 1-2, get Borneolum Syntheticum, stone catechu, Sanguis Draxonis, Radix Notoginseng, Olibanum, Margarita powder and Flos Carthami for the raw material composition according to described decubital ulcer skin-active ointment and pulverize, after sieving, mix homogeneously obtains mixed-powder; Mixed-powder is added in vaseline, to stir to paste and obtain decubital ulcer skin-active ointment.
4. preparation method as claimed in claim 3, is characterized in that, the order number of described pulverizing is 100～180 orders.
5. the application that described in the arbitrary claim of claim 1-2, decubital ulcer skin-active ointment treats patients with decubitus in preparation in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410280672.2A CN104083565A (en) | 2014-06-20 | 2014-06-20 | Bedsore skin-activating ointment and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410280672.2A CN104083565A (en) | 2014-06-20 | 2014-06-20 | Bedsore skin-activating ointment and application thereof |
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|---|---|
| CN104083565A true CN104083565A (en) | 2014-10-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410280672.2A Pending CN104083565A (en) | 2014-06-20 | 2014-06-20 | Bedsore skin-activating ointment and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686078A (en) * | 2018-08-10 | 2018-10-23 | 贾玮 | A kind of traditional Chinese powder medicine for treating pressure sore |
| EP3941501A4 (en) * | 2019-03-20 | 2022-12-14 | Alphyn Biologics, LLC | Topical croton lechleri compositions for the treatment of acute bacterial skin or skin structure infection |
| CN116019867A (en) * | 2022-12-05 | 2023-04-28 | 雷晓琴 | Pearl skin-promoting ointment and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366544A (en) * | 2011-08-20 | 2012-03-07 | 钱家美 | Bedsore ointment and preparation method thereof |
-
2014
- 2014-06-20 CN CN201410280672.2A patent/CN104083565A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366544A (en) * | 2011-08-20 | 2012-03-07 | 钱家美 | Bedsore ointment and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 孙芃: "自制褥疮散治疗褥疮的疗效观察", 《中国实用医药》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686078A (en) * | 2018-08-10 | 2018-10-23 | 贾玮 | A kind of traditional Chinese powder medicine for treating pressure sore |
| EP3941501A4 (en) * | 2019-03-20 | 2022-12-14 | Alphyn Biologics, LLC | Topical croton lechleri compositions for the treatment of acute bacterial skin or skin structure infection |
| CN116019867A (en) * | 2022-12-05 | 2023-04-28 | 雷晓琴 | Pearl skin-promoting ointment and preparation method thereof |
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