CN105030958A - Pharmaceutical composition and application thereof - Google Patents
Pharmaceutical composition and application thereof Download PDFInfo
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- CN105030958A CN105030958A CN201510533296.8A CN201510533296A CN105030958A CN 105030958 A CN105030958 A CN 105030958A CN 201510533296 A CN201510533296 A CN 201510533296A CN 105030958 A CN105030958 A CN 105030958A
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- pharmaceutical composition
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Abstract
The invention provides a pharmaceutical composition which contains tetracycline antibiotics, sulfonamide antibiotics, isoniazide, sanguisorba officinalis and borneol. The invention also provides application of the pharmaceutical composition in preparation of medicines for treating scalds and burns or medicines for treating sores or medicines for treating wounds. The pharmaceutical composition provided by the invention has the effects of removing slough and expelling pus, repairing tissues, promoting tissue regeneration and healing, enhancing immunity, clearing away heat and toxic materials, promoting blood circulation to remove blood stasis as well as eliminating swelling and alleviating pain. In recent ten years, clinical tests prove that the pharmaceutical composition provided by the invention is suitable for various burns and scalds, bed sores, abscesses and traumatic wounds. After the pharmaceutical composition is used, the pain of patients can be relieved, the pain can be stopped quickly, the healing speed is high, and scars can be avoided after healing.
Description
Technical field
The invention belongs to drug world, relate to a kind of pharmaceutical composition and application thereof.
Background technology
In daily life, other wounds such as scald, incised wound are very common, at present a lot of hospitals adopt transfusion, have an injection take medicine, the method treatment such as the roasting wrapping of electricity, its treatment time is long, and adds sufferer misery and bear.If adopt Chinese medicine or Chinese patent medicine to process, conventional comprises JINGWANHONG ointment for scald, MEIBAO SHIRUN SHAOSHANG GAO, YUNNAN BAIYAO etc., and these medicines have paste, liquid, Powdered, but treatment effect is not very desirable usually.Adopt above-mentioned conventional method, severe patient also can scar, affects later live and work.
Summary of the invention
The shortcoming of prior art in view of the above, the object of the present invention is to provide a kind of pharmaceutical composition and application thereof, to solve the problems existed in prior art.
Pharmaceutical composition of the present invention, comprises the raw material of following mass fraction: tetracycline antibiotics 15-30 part, sulfa antibiotics 20-33 part, isoniazid 0.1-1.2 part, Radix Sanguisorbae 0.08-1 part, Borneolum Syntheticum 0.01-0.1 part.
Preferably, described pharmaceutical composition, comprises the raw material of following mass fraction: tetracycline antibiotics 18-26 part, sulfa antibiotics 20-26 part, isoniazid 0.1-0.8 part, Radix Sanguisorbae 0.08-0.6 part, Borneolum Syntheticum 0.01-0.08 part.
According to one of embodiment of the present invention, described tetracycline antibiotics be selected from comprise in chlortetracycline, oxytetracycline, tetracycline, doxycycline, methacycline, demeclocycline, his mycin beautiful, minocycline one or more.
According to another embodiment of the present invention, described sulfa antibiotics be selected from sulfadiazine, sulfamethoxazole, sulfasalazine, mafenide, silver sulfadiazine, sulfadimidine, domian, bacteresulf one or more.
Preferably, described sulfa antibiotics is sulfamethoxazole, sulfadiazine and/or bacteresulf.
Preferred further, described pharmaceutical composition also comprises 1-5 mass parts trimethoprim.
Pharmaceutical composition of the present invention, can also add medicine acceptable carrier, makes preparation according to the routine techniques of galenic pharmacy.Pharmaceutically active substance in preparation is pharmaceutical composition of the present invention, can be 0.1-100%, and all the other are medicine acceptable carrier.
Preparation of the present invention can be any can the dosage form of external, these dosage forms comprise: unguentum, powder, suppository, cream, spray, patch, gel, tincture, paste.
The present invention also provides a kind of preparation containing described pharmaceutical composition, and its dosage form comprises: unguentum, powder, suppository, cream, spray, patch, gel, tincture, paste.
Present invention also offers the application of described pharmaceutical composition in the boiling hot burn medicine of preparation treatment.
Present invention also offers the application of described pharmaceutical composition in preparation treatment skin ulcer medicine.
Present invention also offers the application of described pharmaceutical composition in preparation treatment Wound medicine, wherein, wound refers to be caused by scratch, abrade, chop wound, stab, lacerated wound etc.
Pharmaceutical composition of the present invention has putrefaction removing evacuation of pus, repair tissue, granulation promoting hold back mouth, strengthen effect of immunity, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Clinical trial in nearly ten years proves, pharmaceutical composition of the present invention is applicable to all kinds of burn and scald, decubital ulcer, abscess (furuncle) and trauma wounds, after using, can slow down sufferer misery, quickly alleviating pain, healing rate soon, more after preventing from scar.
Detailed description of the invention
Below by way of specific instantiation, embodiments of the present invention are described, those skilled in the art the content disclosed by this description can understand other advantages of the present invention and effect easily.The present invention can also be implemented or be applied by detailed description of the invention different in addition, and the every details in this description also can based on different viewpoints and application, carries out various modification or change not deviating under spirit of the present invention.
embodiment 1
Get tetracycline 20g, sulfadiazine 22g, isoniazid 0.5g, Radix Sanguisorbae 0.4g, Borneolum Syntheticum 0.06g, grind to form fine powder, sieve 200 mesh sieves, and then add liquid paraffin and be ground into pasty state, gradation adds vaseline, grinds well and obtains ointment.
embodiment 2
Fetch earth mycin 18g, sulfamethoxazole 20g, trimethoprim 2g, isoniazid 0.8g, Radix Sanguisorbae 0.08g, Borneolum Syntheticum 0.03g, grinds to form fine powder, and sieve 200 mesh sieves, obtains powder.During use, add appropriate Oleum Sesami, furnishing pasty state, be applied to sufferer place.
embodiment 3
Get minocycline 26g, bacteresulf 33g, trimethoprim 5g, isoniazid 1.2g, Radix Sanguisorbae 1g, Borneolum Syntheticum 0.1g, grind to form fine powder, be then prepared into cream according to a conventional method.
embodiment 4
Get doxycycline 15g, sulfasalazine 33g, isoniazid 1g, Radix Sanguisorbae 0.6g, Borneolum Syntheticum 0.02g, grind to form fine powder, sieve 200 mesh sieves, is then prepared into patch according to a conventional method.
test example
case 1
Patient Lee, man, 57 years old, two degree of scalds: have blister, decortication, red and swollen, severe pain; Adopt the ointment of embodiment 1 to be applied to scald place, every day 2-3 time, after 1 day, severe pain sense disappears, and within 3 days, subsides a swelling afterwards, within 5 days, fully recovers, do not have cicatrix.
case 2
Patient Hu, man, student, 18 years old, hurts the right hand accidentally, and after hospital's wrapping, gnawing pains take no rest, and at hospital transfusion after 7 days, pain is cut down, but has a small amount of pus.Adopt the powder of embodiment 2, add appropriate Oleum Sesami, furnishing pasty state, be applied to sufferer place, change dressings every day once, recovery from illness in 7 days, does not leave any cicatrix.
case 3
Patient: Lee, man, 53 years old, the long furuncle in back, owing to dealing with improperly, ulcer was suppurated, pruritus pain, adopts the patch of embodiment 4 to be affixed on affected part, changes dressings every day once, and no longer pain after 2 days, fully recovered after 7 days.
Claims (10)
1. a pharmaceutical composition, is characterized in that, comprises the raw material of following mass fraction: tetracycline antibiotics 15-30 part, sulfa antibiotics 20-33 part, isoniazid 0.1-1.2 part, Radix Sanguisorbae 0.08-1 part, Borneolum Syntheticum 0.01-0.1 part.
2. pharmaceutical composition as claimed in claim 1, is characterized in that, comprise the raw material of following mass fraction: tetracycline antibiotics 18-26 part, sulfa antibiotics 20-26 part, isoniazid 0.1-0.8 part, Radix Sanguisorbae 0.08-0.6 part, Borneolum Syntheticum 0.01-0.08 part.
3. pharmaceutical composition as claimed in claim 1 or 2, is characterized in that, described tetracycline antibiotics be selected from comprise in chlortetracycline, oxytetracycline, tetracycline, doxycycline, methacycline, demeclocycline, his mycin beautiful, minocycline one or more.
4. pharmaceutical composition as claimed in claim 1 or 2, it is characterized in that, described sulfa antibiotics be selected from sulfadiazine, sulfamethoxazole, sulfasalazine, mafenide, silver sulfadiazine, sulfadimidine, domian, bacteresulf one or more.
5. pharmaceutical composition as claimed in claim 4, it is characterized in that, described sulfa antibiotics is sulfamethoxazole, sulfadiazine and/or bacteresulf.
6. pharmaceutical composition as claimed in claim 5, it is characterized in that, described pharmaceutical composition also comprises 1-5 mass parts trimethoprim.
7. the preparation containing pharmaceutical composition described in any one of claim 1-6, it is characterized in that, the dosage form of described preparation comprises: unguentum, powder, suppository, cream, spray, patch, gel, tincture, paste.
8. as described in any one of claim 1-6, pharmaceutical composition scalds the application in burn medicine in preparation treatment.
9. the application of pharmaceutical composition in preparation treatment skin ulcer medicine as described in any one of claim 1-6.
10. the application of pharmaceutical composition in preparation treatment Wound medicine as described in any one of claim 1-6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510533296.8A CN105030958A (en) | 2015-08-27 | 2015-08-27 | Pharmaceutical composition and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510533296.8A CN105030958A (en) | 2015-08-27 | 2015-08-27 | Pharmaceutical composition and application thereof |
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| CN105030958A true CN105030958A (en) | 2015-11-11 |
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| CN201510533296.8A Pending CN105030958A (en) | 2015-08-27 | 2015-08-27 | Pharmaceutical composition and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381101A (en) * | 2015-12-03 | 2016-03-09 | 张东 | Medicine used for treating burns, scalds and bedsore and preparation method thereof |
| CN105748490A (en) * | 2016-02-26 | 2016-07-13 | 陈鲜 | Quick scald-healing powder and using method thereof |
| WO2021056029A1 (en) * | 2019-09-18 | 2021-03-25 | The Board Of Regents Of The University Of Texas System | Methods and compositions for treating pain and other eph receptor-associated conditions |
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| CN101347531A (en) * | 2007-07-20 | 2009-01-21 | 陈旺金 | External-use medical ointment for burn and scald |
| CN101439104A (en) * | 2008-11-19 | 2009-05-27 | 黄群才 | Medicament for treating burn by 'dry, moistening, dressing' three in one bandaging method |
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2015
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| CN1125139A (en) * | 1995-12-06 | 1996-06-26 | 张金安 | Antiphlogistic analgesic ointment for treating burn |
| CN101347531A (en) * | 2007-07-20 | 2009-01-21 | 陈旺金 | External-use medical ointment for burn and scald |
| CN101439104A (en) * | 2008-11-19 | 2009-05-27 | 黄群才 | Medicament for treating burn by 'dry, moistening, dressing' three in one bandaging method |
| CN101647957A (en) * | 2009-09-07 | 2010-02-17 | 王蔚 | Medicament for treating scald |
| CN102133286A (en) * | 2011-04-01 | 2011-07-27 | 李长欣 | Ointment for treating trauma and preparation method thereof |
| CN102240335A (en) * | 2011-05-16 | 2011-11-16 | 山西新源华康化工股份有限公司 | Compound salinomycin preparation |
| CN103316015A (en) * | 2013-06-26 | 2013-09-25 | 李先强 | Medicine for treating epistaxis through oral administration and external use and method thereof |
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| CN104857116A (en) * | 2014-02-21 | 2015-08-26 | 中国人民解放军第二军医大学 | Applications of traditional Chinese medicine sanguisorba officinalis in preparing antifungal drug synergist |
| CN104000915A (en) * | 2014-04-25 | 2014-08-27 | 张文艳 | Chinese and western combined medicine for treating scalds and burns |
| CN104069326A (en) * | 2014-07-11 | 2014-10-01 | 杨华 | Medicine combination preparation as well as preparation method and application thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381101A (en) * | 2015-12-03 | 2016-03-09 | 张东 | Medicine used for treating burns, scalds and bedsore and preparation method thereof |
| CN105748490A (en) * | 2016-02-26 | 2016-07-13 | 陈鲜 | Quick scald-healing powder and using method thereof |
| WO2021056029A1 (en) * | 2019-09-18 | 2021-03-25 | The Board Of Regents Of The University Of Texas System | Methods and compositions for treating pain and other eph receptor-associated conditions |
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20151111 |