CN105381101A - Medicine used for treating burns, scalds and bedsore and preparation method thereof - Google Patents

Medicine used for treating burns, scalds and bedsore and preparation method thereof Download PDF

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CN105381101A
CN105381101A CN201510881255.8A CN201510881255A CN105381101A CN 105381101 A CN105381101 A CN 105381101A CN 201510881255 A CN201510881255 A CN 201510881255A CN 105381101 A CN105381101 A CN 105381101A
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burn
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张东
徐建江
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands

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Abstract

The invention provides a medicine used for treating burns, scalds and bedsore, which belongs to the technical field of drugs. The medicine used for treating burns, scalds and bedsore is mainly prepared from the following raw materials through pulverizing: in terms of weight parts, 5 to 60 parts of tetracycline antibiotic, 5 to 15 parts of charcoal, 5 to 15 parts of borneol, 5 to 15 parts of alum, 3 to 7 parts of musk and 10 to 30 parts of vitamin B2, wherein the charcoal is originated from a grape vine. The medicine used for treating burns, scalds and bedsore can effectively inhibit propagation of bacteria, has good drug effect, prevents generation of scars after curing and shows good practicality.

Description

A kind of medicine being used for the treatment of burn, scald band bed sore and preparation method thereof
Technical field
The present invention relates to field of pharmaceutical technology, in particular to a kind of medicine being used for the treatment of burn, scald band bed sore and preparation method thereof.
Background technology
Minor burn, to scald, have bedsores be common phenomenon in life, for burn, scald, the processing mode taked of decubital ulcer also has a lot, utilize drug coat be very fast, effective method.The medicament categories of selling on the market is various, as moist expose burn ointment, burn pain-relieving ointment, burn spray, band bed sore ointment, but the existing medicine being used for the treatment of burn, scald band bed sore is mainly liquid dosage form or ointment dosage form, and the cardinal symptom of decubital ulcer is local skin festers, the cardinal symptom of minor burn, scald is that wound surface produces vesicle, patient feels injury place severe pain, easy infection, suppuration cause injury place liquid to increase, if now adopt the medicine of liquid dosage form or ointment dosage form to process, then be unfavorable for wound healing, easily grow more antibacterial.And the medicine of liquid dosage form easily flows down along skin, leave injury surface, drug effect is poor; And ointment dosage form needs to smear at injury place to scatter, when carrying out this kind of operation, patient is by hurt like hell.
In addition, the existing medicine being used for the treatment of burn, scald band bed sore is utilized to process, after the recovery from illness of injury place, also can scar, very ugly, particularly hinder for patient for women, the cicatrix stayed can cause psychology to feel oneself inferior especially.
Summary of the invention
In view of this, the invention provides a kind of medicine being used for the treatment of burn, scald band bed sore and preparation method thereof, utilize the existing drug treating injury place being used for the treatment of burn, scald band bed sore, easy breed bacteria to improve, easily scar is stayed after recovery from illness, and drug effect problem that is poor or hurt like hell when using.
For achieving the above object, the invention provides following technical scheme:
A kind of medicine being used for the treatment of burn, scald band bed sore, obtain primarily of following raw material powder process: count by weight, tetracycline antibiotics 5 ~ 60 parts, 5 ~ 15 parts, Linesless charcoal, Borneolum Syntheticum 5 ~ 15 parts, Alumen 5 ~ 15 parts, 3 ~ 7 parts, Moschus and vitamin B2 10 ~ 30 parts, described Linesless charcoal derives from vine.
Tetracycline antibiotics: be the class broad ectrum antibiotic produced by actinomycetes, be widely used in the infection that various bacteria and rickettsia, chlamydia, mycoplasma etc. cause, there is the effect of bacteria growing inhibiting.
Linesless charcoal: the Linesless charcoal that vine is fired as raw material, has Chinese medicine character, has the effect such as antiinflammatory, absorption pus and blood in burn treating.
Borneolum Syntheticum: Borneolum Syntheticum can suppress or kill the clinical common bacterias such as staphylococcus aureus, beta hemolytic streptococcus, viridans streptococci, has antibacterial action, but also has the effect of antiinflammatory, detumescence, pain relieving.
Alumen: belong to mineral Chinese medicine, external can be detoxified parasite killing, dampness removing to stop itchin.
Moschus: the effect with analgesia, detumescence, blood circulation promoting and blood stasis dispelling.
Vitamin B2: participate in biological oxidation and energy metabolism in body, relevant with the metabolism of carbohydrate, protein, nucleic acid and fat, the utilization rate of body to protein can be improved, enhancing development, safeguard the integrity of skin and cell membrane.
Relative to prior art, the present invention includes following beneficial effect: each component materials mixes by the present invention, each raw material complements each other.After making powder; be sprinkled upon on the wound surface of burn, scald; the growth of the antibacterial that the tetracycline antibiotics in powder suppresses skin wound to infect, while antibacterial, kill elimination to already present antibacterial, Linesless charcoal viny is in the sterilization process of tetracycline antibiotics; the pus and blood that wound surface produces is adsorbed; play antiinflammation, but also play protection to it, incrustation grumeleuse forms protective layer; separate the external world, avoid other bacteriological infection to wound surface.And also containing Borneolum Syntheticum in powder, Borneolum Syntheticum can not only promote that Linesless charcoal carries out antiinflammatory, also has effect of pain relieving.The antibacterial that this medicine being used for the treatment of burn, scald band bed sore can exist wound surface effectively kills and removes, and avoids bacteria breed.
Wound surface humidity after empyrosis is higher, also may there are blood stains etc., and the wound surface of decubital ulcer is also in the shape that festers.And due to this medicine being used for the treatment of burn, scald band bed sore be powder, so after empyrosis has bedsores, be sprinkled upon wound surface.Medicated powder adheres to forming good laminating with wound surface skin, and the medicinal ingredient in powder just makes full use of this kind of contact, and acts on wound surface skin, good drug efficacy, long action time.And just because of the covering of powder, and reducing the probability that wound surface contacts with air, the very big dust, antibacterial etc. reduced in air is attached on wound surface skin, wound surface is caused to the probability of secondary injury.In addition, because this medicine being used for the treatment of burn, scald band bed sore can stick on wound surface, thus Moschus wherein and vitamin B2 can long duration of action on wound surface, promote the metabolism of wound surface skin, take off dead bark, desalination cicatrix, make the wound surface place after fully recovering almost there is no cicatrix.
The medicine being used for the treatment of burn, scald band bed sore provided by the invention can effectively avoid injury wound surface to be subject to secondary injury, and after injury wound healing, also almost do not have cicatrix, fine hair also can grow again, good effect, instant effect, and practicality is high.
Preferably, be above-mentionedly used for the treatment of in the medicine of burn, scald band bed sore, described tetracycline antibiotics is the mixture of oxytetracycline and tetracycline, and described oxytetracycline 25 ~ 45 parts, described tetracycline 5 ~ 15 parts.
Oxytetracycline: belong to antibiotics, has broad spectrum antibacterial, can suppress various bacteria, larger virus and a part of protozoon.Oxytetracycline energy bacteria growing inhibiting, also has the effect of sterilization, and its mechanism of action is the synthesis of interferencing protein.Oxytetracycline toxic and side effects is little.
Tetracycline: broad-spectrum antibacterial agent, has bactericidal action, has good inhibitory action to gram positive bacteria, negative bacterium, rickettsia, filterable virus, Spirochaetes and even protozoon class.
By oxytetracycline and tetracycline used in combination, the two has the effect of mutually promoting, and concertedness is high, and bacteriostasis and sterilization is effective.
Present invention also offers a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, described mixed raw material is become powder.
In use, the medicine being used for the treatment of burn, scald band bed sore of powder is sprinkled upon injury place, easy to operate, good drug efficacy, instant effect.
Preferably, to be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, to prepare powder and comprise the following steps:
A. raw material described in ground and mixed, obtains mixed powder;
B. mixed powder described in dry in the sun.
Grinding can make each raw material mix fully, and after dry in the sun, the moisture in mixed powder just can volatilize substantially, just can obtain powder.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, described step a is further:
A1. grind tetracycline antibiotics, Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 respectively, then mix, then add Moschus, obtain mixed powder;
A2. by described mixed powder grinding 4 ~ 5 times, until particle diameter is more than 100 orders.
Component materials is first ground respectively, obtain preliminary comminuting matter, so, mixing system material can be convenient to, then grind after all mixing of materials again, so, easy to use and that coating is good powder can be obtained, and each component materials mix homogeneously also can be made in process of lapping, coordinate assembly and obtain the best medicine being used for the treatment of burn, scald band bed sore.And in component materials, because Moschus is softer, so without the need to initially grinding, only need be added when mixed grinding, increase the uniformity of ingredient.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, also comprise after described step b: c. repeating said steps a2.Carry out regrind and can make the abundant mix homogeneously of each component materials on the one hand, on the other hand, due to after a dry in the sun, a small amount of moisture may be also there is in mixed powder, these a small amount of moisture just may cause mixed powder to lump, and carry out regrind and just the little caking that wherein may exist can be ground into powder.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, also comprise after described step c: repeating said steps b, obtain powder.Secondary airing can remove the moisture in mixed powder thoroughly.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, in described step a1, described tetracycline antibiotics grinding 8 ~ 24min, described Linesless charcoal grinding 3 ~ 7min, described borneol and grinding 3 ~ 7min, described Alumen grinding 2 ~ 5min, described vitamin B2 grinding 1 ~ 2min.For different material compositions, carry out the grinding of different time, lap is targeted, and flexibly, practicality is high in grinding.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, the method for airing in described step b is: by the dry in the sun 10 ~ 15 days at 30 ~ 40 DEG C of described mixed powder.This kind of method for airing can make the moisture in mixed powder vapor away more thoroughly, reduces the water content in mixed powder, obtained dry loose powder, easy to use.
Preferably, be above-mentionedly used for the treatment of in the preparation method of the medicine of burn, scald band bed sore, the Ginding process in described step a is dry grinding method.Dry grinding is owned by France in smooth grinding, is abrasive material is evenly embedded in lap tool surface layer in pressure, need only be coated with the grinding that the auxiliary material such as a small amount of stearic acid mixing fat carry out during grinding on lap tool surface.The powder particle size that dry grinding method obtains is little, becomes powder effective, is conducive to powder lot dispersing.
In the present invention, the milling time all preferably 8 ~ 12min of oxytetracycline and tetracycline.
Compared with prior art, beneficial effect of the present invention is:
(1) anti-bacteria increases, and reduces the secondary injury that wound surface is subject to;
(2) good drug efficacy, reduces fast, applies effective;
(3) wound healing, desalinates cicatrix simultaneously, and skin recovered as the past.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment one
Embodiments of the invention one provide a kind of medicine being used for the treatment of burn, scald band bed sore, obtain: count by weight, oxytetracycline 5 parts, 5 parts, vine Linesless charcoal, Borneolum Syntheticum 5 parts, Alumen 5 parts, 3 parts, Moschus and vitamin B2 10 parts primarily of following raw material powder process.
The present embodiment additionally provides a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, comprises the following steps:
A. by oxytetracycline, vine Linesless charcoal, Borneolum Syntheticum, Alumen, Moschus, vitamin mixing, being ground to particle diameter is 100 orders, obtains mixed powder;
B. dry in the sun mixed powder.
Embodiment two
Embodiments of the invention two provide a kind of medicine being used for the treatment of burn, scald band bed sore, obtain primarily of following raw material powder process: count by weight, tetracycline 60 parts, 15 parts, vine Linesless charcoal, Borneolum Syntheticum 15 parts, Alumen 15 parts, 7 parts, Moschus and vitamin B2 30 parts.
The present embodiment additionally provides a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, comprises the following steps:
A. tetracycline, vine Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 is ground respectively, tetracycline grinding 12min, vine Linesless charcoal grinding 3min, borneol and grinding 3min, Alumen grinding 2min, vitamin B2 grinding 1min, then grinds the mixing of materials obtained by each composition, be mixed into Moschus simultaneously, obtain mixed powder;
Mixed powder is ground 5 times, until particle diameter is 120 orders;
B. by mixed powder dry in the sun 10 days at 40 DEG C.
Embodiment three
Embodiments of the invention three provide a kind of medicine being used for the treatment of burn, scald band bed sore, obtain primarily of following raw material powder process: count by weight, oxytetracycline 25 parts, tetracycline 5 parts, 8 parts, vine Linesless charcoal, Borneolum Syntheticum 6 parts, Alumen 6 parts, 4 parts, Moschus and vitamin B2 15 parts.
The present embodiment additionally provides a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, comprises the following steps:
A. oxytetracycline, tetracycline, vine Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 is ground respectively, oxytetracycline grinding 9min, tetracycline grinding 10min, the grinding of vine Linesless charcoal 4min, borneol and grinding 4min, Alumen grinding 3min, vitamin B2 grinding 1.5min, then each composition is ground the mixing of materials obtained, then add Moschus, obtain mixed powder;
Mixed powder is ground 5 times, until particle diameter is 130 orders;
B. by mixed powder dry in the sun 14 days at 32 DEG C.
Embodiment four
Embodiments of the invention four provide a kind of medicine being used for the treatment of burn, scald band bed sore, obtain primarily of following raw material powder process: count by weight, oxytetracycline 45 parts, tetracycline 15 parts, 14 parts, vine Linesless charcoal, Borneolum Syntheticum 14 parts, Alumen 14 parts, 6.5 parts, Moschus and vitamin B2 22 parts.
The present embodiment additionally provides a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, comprises the following steps:
A. oxytetracycline, tetracycline, vine Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 is ground respectively, oxytetracycline grinding 11min, tetracycline grinding 10min, the grinding of vine Linesless charcoal 6min, borneol and grinding 5.5min, Alumen grinding 4min, vitamin B2 grinding 2min, then each composition is ground the mixing of materials obtained, then add Moschus, obtain mixed powder;
Mixed powder is ground 4 times, until particle diameter is 115 orders;
B. by mixed powder dry in the sun 13 days at 37 DEG C.
Embodiment five
Embodiments of the invention five provide a kind of medicine being used for the treatment of burn, scald band bed sore, obtain primarily of following raw material powder process: count by weight, oxytetracycline 35 parts, tetracycline 10 parts, 10 parts, the vine Linesless charcoal of the age of tree 10 years, Borneolum Syntheticum 10 parts, Alumen 10 parts, 5 parts, Moschus and vitamin B2 20 parts.
The present embodiment additionally provides a kind of above-mentioned preparation method being used for the treatment of the medicine of burn, scald band bed sore, comprises the following steps:
A. dry grinding method is utilized, grind oxytetracycline, tetracycline, vine Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 respectively, oxytetracycline grinding 10min, tetracycline grinding 10min, Linesless charcoal grinding 5min, borneol and grinding 5min, Alumen grinding 3min, vitamin B2 grinding 1min, then grinds the mixing of materials obtained by each composition, be mixed into Moschus simultaneously, obtain mixed powder;
Mixed powder is ground 4 times, until particle diameter is 110 orders;
B. by mixed powder dry in the sun 15 days at 30 DEG C;
C. the powder after dry in the sun is ground 4 times again;
D. powder is repeated dry in the sun 15 days at 30 DEG C, obtain powder.
What the present embodiment obtained is used for the treatment of the medicine of burn, scald band bed sore compared with existing burn and scald drug, mainly contains following advantage:
(1) leaving no scar after healing, non-pigment precipitates.This medicine was through more than 30 years, and the observation of the Clinical application and research person of thousands of routine patient is followed up a case by regular visits to, and uses the patient of this Drug therapy after learning all wounds immediately, and none example retains cicatrix, does not also have pigementation.And existing medicine is to dark II degree and above burn, can remain cicatrix in various degree after healing, also can cause local function obstacle, this point has write into textbook.
(2) curative effect is quick.The medicine that use the present embodiment provides is compared with medicine of the prior art, and treatment time can shorten 1 ~ 2 times, see table one.
Table one
(3) the easy no pain of Therapeutic Method.The Drug therapy empyrosis utilizing the present embodiment to provide belongs to naturopathy, only needs medical powder variable interval to be coated with to spill in wound face, rapid pain relieving, solid carbon dioxide, incrustation after medication, until decrustation healing voluntarily.And no matter medicine of the prior art takes occlusive dressing or exposure method, all need to carry out various operation and strict requirement gnotobasis, bring inconvenience with painful to the wounded's treatment.
(4) can not infect in therapeutic process.Utilize the Drug therapy that the present embodiment provides, dark more than II degree empyrosis is without the need to artificial surgery skin grafting again, and wound can normal healing.And existing Therapeutic Method is often because condition is limited, or sterilization tight and cause infecting, sb.'s illness took a turn for the worse, serious burn needs artificial surgery skin grafting, and wound could heal, even and if after healing, wound is also by remaining permanent scar.
(5) medicine source is extensive, with low cost.The ingredient that the present embodiment provides extensively is present in nature, be easy to obtain, and cost is low.
To sum up, the exploitation of the present embodiment, contributing greatly the mankind's one beyond doubt, medical history is also a quantum jump.
In addition, theoretically, empyrosis is a kind of sudden common disease, and be apt to occur in summer and autumn and Human body package position, etiology and pathogenesis is body and is burnt by heating power or chemical drugs, therefore the medicine one method extensively treating that the present embodiment provides.Explain from principle, the medicine that the present embodiment provides:
(1) there is the effect of protection empyrosis wound surface; very soon after medication on wound surface, form one deck crust layer; this may be that the tannin of the fibrin that oozes out of wound surface and this medicine is combined into; thus barrier action is had to the permeability of blood capillary; effectively control the loss of body fluid; prevent the intrusion of antibacterial simultaneously, be conducive to the control of suffering a shock.Therefore, under the condition of station out of office, early prevention infected and prevents the generation of septicemia from can play useful effect, also after rescuing burn patient, sending the condition of creating.
(2) bacteriostatic experiment:
(1) this medicine has the antibacterial of wide spectrum and bactericidal action, all has suppression in various degree and killing action especially to bacillus pyocyaneus, staphylococcus, dysentery bacterium, escherichia coli, Bacillus proteus;
(2) this medicine PH is about 5, and its pH value is adjusted to 6 ~ 8, and its bacteriostasis is also unaffected, act on constant after high temperature (120 DEG C) sterilizing, adding preservative agent does not observe a year and a half at normal temperatures, and appearance color does not change, without bacterial growth, its fungistatic effect is unaffected;
(3) this medicine and the broad-spectrum antibiotic such as penicillin and telracycline family Combined Trials, coordinative role is not obvious, but without antagonism, therefore, this medicine can use with other antibiotics simultaneously.
Because this medicine has effect of heat-clearing and toxic substances removing, bacteriostasis and sterilization, reducing swelling and alleviating pain, putrefaction-removing granulation-promoting; therefore protect wound surface rapidly after medication; define locally aseptic and control infection; the crust film that the fibrin simultaneously oozed out because of body and the tannin in this medicine are formed encloses rapidly the blood capillary of breakage; prevent the oozing out of tissue fluid, lose; add that this medicine has effect of putrefaction-removing granulation-promoting; facilitate wound healing; wound surface obtains in time to be closed and protection; be not subject to external interference and natural granulation promoting heals, thus rear without cicatrix and pigmentation.According to medical science reasoning, the fields such as this medicine also can be widely used in treatment gunshot wound, wound, cureless surgical infection disease and medical cosmetology, prospect is very wide.
It is investigated visit, the ten multi-infection diseases such as utilize the early stage skin-grafting of this Drug therapy venom, folliculitis, furuncle, abscess, dactylitis, eczema concurrent infection, upper and lower limb chronic ulcer, infection of incisional wound, popularity wound, all obtain satisfied effect.
When the medicine using the present embodiment to provide, there is the severe cases of General Symptoms, by the conventional treatment by oral administration of medicines of doctor trained in Western medicine.This medicine of external variable interval dusting flap coverage is until wound normal healing.Small size, either shallow burn and scald, alone medicine can thoroughly be cured.As wrong treatment, lose and control the patient causing infection suppurates, after thorough debridement, disinfection, use this Drug therapy instead and still can reach foregoing advantages.
The medicine that the present embodiment provides was through more than 30 years, and thousands of routine patient clinical application, no matter the empyrosis of which kind of reason, as long as adopt this Drug therapy after wound, all obtains satisfied effect.Except indivedual cause specific turns and controls, none routine failure case.Through 100 routine patients are followed up a case by regular visits to and collection of data, arrangement, statistics, analysis, the result obtained be cure rate up to 100%, and residual cicatrix of none example, or there is pigementation.See table two.
Table two
In addition, the medicine being used for the treatment of burn, scald band bed sore of other embodiment is used for clinical treatment, the effect of generation is consistent with above-mentioned result of the test.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. one kind is used for the treatment of the medicine of burn, scald band bed sore, it is characterized in that, obtain primarily of following raw material powder process: count by weight, tetracycline antibiotics 5 ~ 60 parts, 5 ~ 15 parts, Linesless charcoal, Borneolum Syntheticum 5 ~ 15 parts, Alumen 5 ~ 15 parts, 3 ~ 7 parts, Moschus and vitamin B2 10 ~ 30 parts, described Linesless charcoal derives from vine.
2. the medicine being used for the treatment of burn, scald band bed sore according to claim 1, is characterized in that, described tetracycline antibiotics is the mixture of oxytetracycline and tetracycline, and described oxytetracycline 25 ~ 45 parts, described tetracycline 5 ~ 15 parts.
3. the preparation method being used for the treatment of the medicine of burn, scald band bed sore described in claim 1 or 2, is characterized in that, described mixed raw material is become powder.
4. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 3, is characterized in that, prepares powder and comprises the following steps:
A. raw material described in ground and mixed, obtains mixed powder;
B. mixed powder described in dry in the sun.
5. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 4, is characterized in that, described step a is further:
A1. grind tetracycline antibiotics, Linesless charcoal, Borneolum Syntheticum, Alumen and vitamin B2 respectively, then mix, then add Moschus, obtain mixed powder;
A2. by described mixed powder grinding 4 ~ 5 times, until particle diameter is more than 100 orders.
6. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 5, is characterized in that, also comprises after described step b: c. repeating said steps a2.
7. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 6, is characterized in that, also comprises: repeating said steps b, obtain powder after described step c.
8. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 5, it is characterized in that, in described step a1, described tetracycline antibiotics grinding 8 ~ 24min, described Linesless charcoal grinding 3 ~ 7min, described borneol and grinding 3 ~ 7min, described Alumen grinding 2 ~ 5min, described vitamin B2 grinding 1 ~ 2min.
9. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 4, is characterized in that, the method for airing in described step b is: by the dry in the sun 10 ~ 15 days at 30 ~ 40 DEG C of described mixed powder.
10. the preparation method being used for the treatment of the medicine of burn, scald band bed sore according to claim 4, is characterized in that, the Ginding process in described step a is dry grinding method.
CN201510881255.8A 2015-12-03 2015-12-03 Medicine used for treating burns, scalds and bedsore and preparation method thereof Pending CN105381101A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106727880A (en) * 2016-12-31 2017-05-31 李明宝 Treat the Chinese medicine composition of burn and scald
CN109453192A (en) * 2018-12-06 2019-03-12 沧州爱农生物科技有限公司 A kind of compound hydrochloric acid terramycin alumen borneol effervescent tablet and preparation method thereof

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CN1528413A (en) * 2003-10-14 2004-09-15 华 阎 Medicine for treating bum, empyrosis and bedsore
CN101234148A (en) * 2008-03-06 2008-08-06 张金声 Pure Chinese medicine powder for treating bedsore, scald and burn
CN101850000A (en) * 2010-06-22 2010-10-06 张十方 Chinese and western medicinal composition for treating empyrosis
CN104367906A (en) * 2014-11-17 2015-02-25 晏洪友 Medicine for treating burns and scalds, acne rosacea and acnes and preparation method thereof
CN105030958A (en) * 2015-08-27 2015-11-11 赵文华 Pharmaceutical composition and application thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1528413A (en) * 2003-10-14 2004-09-15 华 阎 Medicine for treating bum, empyrosis and bedsore
CN101234148A (en) * 2008-03-06 2008-08-06 张金声 Pure Chinese medicine powder for treating bedsore, scald and burn
CN101850000A (en) * 2010-06-22 2010-10-06 张十方 Chinese and western medicinal composition for treating empyrosis
CN104367906A (en) * 2014-11-17 2015-02-25 晏洪友 Medicine for treating burns and scalds, acne rosacea and acnes and preparation method thereof
CN105030958A (en) * 2015-08-27 2015-11-11 赵文华 Pharmaceutical composition and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106727880A (en) * 2016-12-31 2017-05-31 李明宝 Treat the Chinese medicine composition of burn and scald
CN109453192A (en) * 2018-12-06 2019-03-12 沧州爱农生物科技有限公司 A kind of compound hydrochloric acid terramycin alumen borneol effervescent tablet and preparation method thereof

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