CN1528413A - Medicine for treating bum, empyrosis and bedsore - Google Patents

Medicine for treating bum, empyrosis and bedsore Download PDF

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Publication number
CN1528413A
CN1528413A CNA2003101058270A CN200310105827A CN1528413A CN 1528413 A CN1528413 A CN 1528413A CN A2003101058270 A CNA2003101058270 A CN A2003101058270A CN 200310105827 A CN200310105827 A CN 200310105827A CN 1528413 A CN1528413 A CN 1528413A
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medicine
burn
portions
vegetable oil
radix
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CN1261117C (en
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华 阎
阎华�
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Abstract

The present invention relates to a medicine for high-effectively and quickly curing burn, scald, electric injury, bed sore and various sore and psora infections with obvious therapeutic effect. The main composition of said medicine comprises (by weight portion) 10-20 portions of rhubarb, 0.1-2 portions of pearl, 2-10 portions of calcined alum, 10-35 portions of calcined gypsum, 1-3 portions of borneol, 3-5 portions of beeswax and 30-50 portions of vegetable oil. Besides, in the above-mentioned composition the bovine bezoar, musk and Span also can be added. Said invention also provides its preparation method and concrete steps.

Description

A kind of medicine and method for making thereof for the treatment of burn and scald, decubital ulcer
Technical field
This medicine belongs to the treatment skin burn and scald and injures para-infectious medicines such as decubital ulcer.
Background technology
Burn is a kind of commonly encountered diseases.Patient is painful big, especially at the burn initial stage.Burn is in agglutination, and wound surface is easily infected, and healing time is longer.Very easily produce hypertrophic cicatrix after the healing, cause deformity and dysfunction.And medical expense is higher.For burn wound being healed as early as possible and preventing that the later stage scar hyperplasia from being the difficult point and the emphasis of present burn treating, also be simultaneously the important indicator of estimating burn treating level height.The wound surface medicine for external use plays an important role in the burn treatment.At ordinary times or wartime, middle small size II degree is scalded and is occupied the majority, and all accounts for whole aing burn case more than 80%.This part patient's main Therapeutic Method is a wound surface local application, so the quality of medicine plays crucial effect.Husky cloth of many at present employing vaseline and treatments such as 1% silver sulfadiazine solution or upright credible gel have certain effect.Though the wound surface external used medicine is of a great variety clinically at present, promoting healing and preventing that effect is neither enough desirable aspect the cicatrix still do not have a kind of more gratifying medicine.Also there is the not high shortcoming of curative effect of medication in the treatment that thunderbolt wound, decubital ulcer and various skin ulcer scabies are infected in addition.Still do not have a kind of efficiently, fast at present, can control the medicine that burn and scald can be treated skin ulcer scabies class again.Exist treatment time long for burn and scald, easily stay shortcomings such as cicatrix.
Summary of the invention
The objective of the invention is to avoid the above-mentioned deficiency of existing therapy, a kind of efficient more rapid healing burn and scald, decubital ulcer and the para-infectious medicine of various skin ulcer scabies are provided; Make burn and scald after healing, not stay cicatrix.
For achieving the above object, the applicant through clinical practice for many years, excavates out a kind of new wound surface medicine for external use according to Traditional Chinese medical theory, and proof has better therapeutic effect really.
This treatment burn and scald injures the drug main of decubital ulcer will be made of (weight portion) following ingredients:
(1) Radix Et Rhizoma Rhei 10-20 part
(2) Margarita 0.1-2 part
(3) dried Alumen 2-10 part
(4) Gypsum Fibrosum Preparatum 10-35 part
(5) Borneolum Syntheticum 1-3 part
(6) Cera Flava 3-5 part
(7) vegetable oil 30-50 part
Here said vegetable oil can be Oleum sesami, Oleum Arachidis hypogaeae semen or Oleum Glycines etc.
In order further to improve effect, on the basis of above-mentioned component, also can comprise following composition (weight portion):
Calculus Bovis 0.01-0.1 part
Moschus 0.001-0.01 part
Span 40 0.5-2 part
The medicine of above-mentioned compatibility should be made ointment and use.Can adopt existing various ointment method for making for this reason.Common Chinese teacher can both be implemented according to a conventional method.But in order to reach better effect, preferably make extractum rhei earlier, vegetable oil, the Cera Flava with heating mixes again, adds other Chinese medicine fine powder at last.
Prepare the method for said medicine, preferably include following steps:
(1) Radix Et Rhizoma Rhei is made fluid extract, be heated to about 80 ℃;
(2) vegetable oil, Cera Flava and span (can not add) are mixed and heated to 80 ℃ and form liquid;
(3) with above-mentioned two liquid mixing homogenizing, be cooled to 35-40 ℃;
(4) fine powder of adding other medicines stirs.
This medicine is the mixture of plurality of Chinese, has only when they compatibilities and uses jointly, and cooperation just can produce beyond thought new more superior effect, so the present invention is creative.
This pharmaceutical composition also has significant curative effect except that burn and scald, electric burn are had the peculiar curative effect to decubital ulcer and the infection of various skin ulcer scabies.Said composition is made generally in putty-type, and trade name is " magnificent flourish skin health ointment " or " BINGSHI wound healing ointment ".
The burn and scald of the not useful as yet above-mentioned composition treatment of domestic and foreign literature at present injures the report of diseases such as decubital ulcer.Through clinical verification, its a kind of really new drug that is better than existing various medicines.
The specific embodiment
Below in conjunction with embodiment the present invention is done and to describe in further detail:
Prescription one:
Radix Et Rhizoma Rhei 15 grams, Margarita 1 gram, dried Alumen 6 grams, Gypsum Fibrosum Preparatum 20 grams, Borneolum Syntheticum 2 grams, Cera Flava 4 grams, vegetable oil 40 grams.
Prescription two:
On prescription one basis, increase Calculus Bovis 0.05 gram, Moschus 0.005 gram and span 1 gram.
To fill a prescription two is the processing technology that example illustrates this medicine:
1, make fine drug powder: get Margarita 100 gram pulverizing porphyrizes in the prescription earlier, again with Calculus Bovis 5 grams, Moschus 0.5 gram facing-up mixing is crossed 120 mesh sieves.Borneolum Syntheticum 200 grams are ground into powder with dried Alumen 600 grams, cross 120 mesh sieves behind the porphyrize, and Gypsum Fibrosum Preparatum 2000 grams are pulverized the back and crossed 120 mesh sieves, and above-mentioned each fine powder is pressed the abundant mix homogeneously of facing-up method, and are standby.
2, extract extractum rhei: get Radix Et Rhizoma Rhei 1500 grams and pulverized 120 mesh sieves,, measured 2 hours for 6 times for the first time with the reflow of alcohol lixiviate of 80% concentration 3 times, 4 times of amounts of second and third time difference, the time was respectively 1.5 and 1 hours.Merging filtrate reclaims ethanol through decompress filter, makes it to be condensed into fluid extract, and it is standby to be called second liquid.
3, make substrate: get Oleum sesami 4000 grams, Cera Flava 400 grams and span (40) 100 grams are heated to about 80 ℃ jointly, form thick liquid, claim first liquid.
4, mix: with Oleum sesami, the first liquid of Cera Flava and span composition joins in the above-mentioned Extractum Rhei Liquidum second liquid under insulated and stirred, and it is complete that the quick stirring of continuation makes it emulsifying, adds the said medicine powder when being cooled to 35~40C, does the homogenizing processing at last and gets final product.
The method that adopts prescription one to make is basic identical with prescription two, just reduces several compositions.
On the basis of this medicine claim, also may add the other medicines composition,, all belong to the protection domain of this patent as Borax, Calamina, argentum powder, Hydrargyri Oxydum Rubrum etc.
In, the Western medicine method of making ointment also has a lot, all may be used for this medicine and make.The protection domain that all belongs to this patent of all this medicament composing prescriptions of employing.
When using this medicine, wound surface is with 1% bromo geramine or other pharmacy disinfection, and cleans with normal saline.Then China's flourish skin health ointment evenly is applied to the affected part, the about 1~2mm of thickness takes exposure method.Once-a-day in early days, the next day of the later stage once.Gauze coating wrapping after the also available sterilization covers.
The Fourth Military Medical University's Xijing hospital burn department and The People's Hospital's Burn and Plastic Surgery Dept. have all carried out clinical verification to this medicine, and be remarkably productive.Detailed report is arranged, limit by length, can not give unnecessary details one by one.As examine and to enclose at any time.
This medicine is compared with existing various similar medicines, has better sterilization, putrefaction-removing granulation-promoting, detoxifcation convergence and anti-inflammatory analgetic effect.Its eutherapeutic reason may be to have improved local microcirculation, has promoted epithelial cell activation and increment, thereby has quickened wound healing.To be expected to become present treatment burn wound, one of medicine that particularly dark II burn wound is ideal.
Clinical data
Xijing hospital of The Fourth Military Medical University from May, 1998 to August, with dark II burn patient 34 examples of magnificent flourish skin health Ointment in Treatment, maximum wound surface 30 * 18cm 2, minimum is 5 * 4.5cm 2, the self-controlled group wound surface is with traditional vaseline oil yarn.Other is all treated routinely and carries out in the treatment whole process.Conclusion is: magnificent flourish skin health can be accelerated the epithelium migration velocity, promotes wound healing; Stronger anti-infection ability is arranged; Substantially not bitterly, the method for changing dressings is simple when changing dressings; Medicine raw material wide material sources, reasonable price; Safety is good, has no side effect.
The People's Hospital's Burn and Plastic Surgery Dept. is selected clinical wound surface case totally 28 examples, patients with bedsore 5 examples wherein, 7 of bedsore wounds, 3 of II degree, 4 of III degree; Area 2-3 * 4-10cm; Concurrent infection in various degree.Fire victim's 16 examples, 21 of burn woundes; Liquefied petroleum gas 9 examples of burning wherein, boiled water is scalded 6 examples, flame burn 2 examples, petrol burn 2 examples, prepared food oil and each 1 example of vapours burn; Burn surface area 4%-85%, dark II degree area 17+19.91%.Matched group burn wound adopts the husky and silver-colored gauze external application wrapping in the close shallow lake of 1% sulfanilamide of vaseline oil, and part exposes treatment for being coated with outward.There is 1 routine wound surface to contrast with upright credible gel (Italian Sha's weights is produced).The result shows that healing time all has obviously in advance than matched group, and effective percentage 100% particularly adopts the sudden and violent treatment of leaking.
Another distinguishing feature of this medicine is, not only can control burn, can also control decubital ulcer etc., helps the reparation of multiple wound surface.The early stage wound surface of this group 21 example burn are used after the magnificent flourish Ointment in Treatment and to be begun pain relieving in about 30 minutes; Shallow II degree wound healing time on average shifts to an earlier date 3-5 days than matched group.Dark II degree wound healing time shifts to an earlier date 5-6 days than matched group.Exposure treatment at the flourish ointment of treatment China of shallow II degree burn wound not only is better than phonetic shallow lakes of 1% sulfanilamide silver, founds credible gel, and obviously is better than the bandaging method for treating of Hua Rong.In the deep ii degree burn Wound treating, the exposure of magnificent flourish ointment treatment also obviously is better than the exposure treatment of all bandaging method for treating and silver sulfadiazine.And not skin-grafting of the healing of all deep ii degree burn wound surface, do not see cicatrix after the healing.
Untoward reaction takes place in none example so far in the process of using magnificent flourish Ointment in Treatment burn and bedsore wound.

Claims (4)

1, a kind ofly treat the medicine that burn and scald injures decubital ulcer, it is characterized in that mainly forming (weight portion) by following composition:
(1) Radix Et Rhizoma Rhei 10-20 part
(2) Margarita 0.1-2 part
(3) dried Alumen 2-10 part
(4) Gypsum Fibrosum Preparatum 10-35 part
(5) Borneolum Syntheticum 1-3 part
(6) Cera Flava 3-5 part
(7) vegetable oil 30-50 part
2, medicine as claimed in claim 1 is characterized in that also comprising following composition (weight portion):
Calculus Bovis 0.01-0.1 part
Moschus 0.001-0.01 part
Span 0.5-2 part
3, the method for preparing the described medicine of claim 1 is characterized in that comprising the steps:
(1) Radix Et Rhizoma Rhei is made fluid extract, be heated to about 80 ℃;
(2) vegetable oil, Cera Flava Hybrid Heating are formed liquid for 80 ℃;
(3) with two liquid mixing homogenizing, be cooled to 35-40 ℃;
(4) fine powder of adding other medicines stirs.
4, the method for preparing the described medicine of claim 2 is characterized in that comprising the steps:
(1) Radix Et Rhizoma Rhei is made fluid extract, be heated to about 80 ℃;
(2) vegetable oil, Cera Flava and span Hybrid Heating are formed liquid for 80 ℃;
(3) with two liquid mixing homogenizing, be cooled to 35-40 ℃;
(4) fine powder of adding other medicines stirs.
CNB2003101058270A 2003-10-14 2003-10-14 Medicine for treating bum, empyrosis and bedsore Expired - Lifetime CN1261117C (en)

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CN1261117C CN1261117C (en) 2006-06-28

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104490932A (en) * 2014-12-29 2015-04-08 高玉萍 Externally-used medicine for recovering burned cortical tissue and preparation method thereof
CN104739870A (en) * 2015-04-15 2015-07-01 刘国良 Ointment for treating burns and scalds
CN105148147A (en) * 2015-10-21 2015-12-16 覃佳林 Traditional Chinese medicine for treating wound or bedsore infection and preparation method thereof
CN105381101A (en) * 2015-12-03 2016-03-09 张东 Medicine used for treating burns, scalds and bedsore and preparation method thereof
CN108186712A (en) * 2018-03-16 2018-06-22 唐天左 The production method of SHENGJI BAIYU GAO

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102416089B (en) * 2011-11-18 2013-08-28 韩传瑞 Externally applied Chinese herbal ointment and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104490932A (en) * 2014-12-29 2015-04-08 高玉萍 Externally-used medicine for recovering burned cortical tissue and preparation method thereof
CN104490932B (en) * 2014-12-29 2018-03-06 高玉萍 It is a kind of to bring back to life external used medicine for scalding burn cortical tissue and preparation method thereof
CN104739870A (en) * 2015-04-15 2015-07-01 刘国良 Ointment for treating burns and scalds
CN105148147A (en) * 2015-10-21 2015-12-16 覃佳林 Traditional Chinese medicine for treating wound or bedsore infection and preparation method thereof
CN105381101A (en) * 2015-12-03 2016-03-09 张东 Medicine used for treating burns, scalds and bedsore and preparation method thereof
CN108186712A (en) * 2018-03-16 2018-06-22 唐天左 The production method of SHENGJI BAIYU GAO

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