CN1095921A - Ointment for burns and scalds and manufacture method thereof - Google Patents
Ointment for burns and scalds and manufacture method thereof Download PDFInfo
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- CN1095921A CN1095921A CN93111265A CN93111265A CN1095921A CN 1095921 A CN1095921 A CN 1095921A CN 93111265 A CN93111265 A CN 93111265A CN 93111265 A CN93111265 A CN 93111265A CN 1095921 A CN1095921 A CN 1095921A
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Abstract
The invention provides a kind of outer coating ointment and manufacture method thereof that is used for the treatment of burn and scald.This ointment contains matrix components and Radix Rehmanniae Preparata, the Radix Rehmanniae, Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli, Radix Arnebiae (Radix Lithospermi), Moschus, dry Exocarpium Citrulli and the Borneolum Syntheticum drug component of Cera Flava and Oleum sesami composition.Its manufacture method is with the Oleum sesami heating, puts into the Radix Rehmanniae Preparata and the Radix Rehmanniae, after soaking intensification, puts into Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and Radix Arnebiae (Radix Lithospermi), and then adding Cera Flava, Moschus and dry Exocarpium Citrulli are put in heating more while stirring, under agitation heating, then remove slag, add Borneolum Syntheticum at last, stir evenly.
Description
The present invention relates to a kind of pharmaceutical preparation and manufacture method thereof, especially relate to a kind of manufacture method of ointment for burns and scalds He this ointment of external.
The existing many schemes of prior art preparation ointment for burns and scalds disclose " a kind of preparation method of ointment for treating burn " as CN1052789A, this method a, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae, Plantula Papaveris are put into Oleum sesami, flood three to seven days; B, heating one hour, temperature remains on 230 ℃ to 240 ℃; Going into pot behind the soaks such as c, elimination Radix Angelicae Sinensis is fried boiling; D, put into Cera Flava, stop heating after the fusing; E, mix and stir river brain and wide borneol, Sanguis Draxonis becomes cream.The ointment that this method is made in use, need earlier the wound surface routine disinfection, with normal saline or furacillin solution flushing, take out liquid in the most blister with asepsis injector, looking the big young pathbreaker's ointment of wound surface evenly divides on aseptic husky cloth, wrap up behind the flap coverage, also available exposure method directly is applied to wound surface with ointment.Generally need not make skin graft, not stay scar.CN1055297A discloses " a kind of manufacture method of skin-moistening burn and scald medicine; " in addition this method is made by substrate and compatibility of drugs, and substrate is vegetable oil (one of Oleum Ricini, Oleum Arachidis hypogaeae semen, Oleum sesami or Oleum Camelliae): the mixture of cured (wax) matter (one of paraffin wax, Cera Flava or spermaceti)=1: 0.03～0.12.Medicine and/or its extract are divided into four groups.First component is to choose 2～3 kinds wantonly from Radix Angelicae Sinensis, Radix Arnebiae (Radix Lithospermi), Cortex Moutan, the Radix Sanguisorbae Radix Angelicae Dahuricae; Second component is to choose 2～3 kinds wantonly from Caulis Spatholobi, Cortex Phellodendri, Rhizoma Coptidis and Radix Et Rhizoma Rhei; The 3rd component is to choose 1～2 kind wantonly from Olibanum, Myrrha and Sanguis Draxonis; The 4th component is to choose 1～2 kind wantonly in Moschus, Borneolum Syntheticum, succinum and the Mirabilitum crystallina, and its weight ratio is a substrate: first component: second component: the 3rd component: the 4th component=1: 0.01～0.06: 0.01～0.06: 0.01～0.06: 0.01～0.06.Its concrete manufacturing process is that lixiviating solution is standby after 1. the first component medicine being soaked 12～48 hours in 5～40 ℃ dosage vegetable oil; 2. will soak the follow-up temperature of continuing rising of 5～20mim in the dosage vegetable oil of the second component medicine prior to 100～200 ℃, in 150～300 ℃ of maintenance 5～20mim, filter, lixiviating solution is standby, and medicinal residues discard; 3. with the 3rd component medicine under 150～300 ℃, and wax (cured) matter is incorporated in the vegetable oil of dosage together, after-filtration to be melted, lixiviating solution is standby, medicinal residues discard; 4. with the 4th component medicine under 30～70 ℃, in the substrate that adds first to the 3rd component medicine, add the medicine of the 4th component, stir, the weak point of aforementioned two schemes is the processing technique complexity, needs to be interrupted to produce.In addition, comply with the ointment that described method is produced, analgesic effect is not ideal enough, uses and generally all need make debridement treatment, and patient's pain of this moment is heavier, debridement treatment causes pain unbearably sometimes, in addition in use, patient also has senses of discomfort such as wound generates heat, itches, and hands touches and can cause traumatic infection, though can not leave obvious cicatrix behind the wound healing, the skin color of the leather generally must not restore.
As everyone knows, adopt Chinese medicine to cure the disease, its close prescription is a lot, but because of adjusting a kind of medicine or part dosage, can bring significant difference sometimes, add the processing procedure difference to drug effect, sometimes also can make drug effect that obvious difference is arranged, therefore, compatibility of drugs and manufacturing process are the key points of drug effect.
One of purpose of the present invention provides a kind of special for treatment of burn and scald, can make the rapid pain relieving by the patient of burn and scald, and wound surface does not generate heat, do not itch, and can make the restorative external-applied ointment of skin color of the leather, two provide a kind of method of making described ointment for burns and scalds.
The present invention can realize by following measure:
Ointment for burns and scalds of the present invention contains substrate and medicine components.Described substrate component is Cera Flava component and Oleum sesami component, and its weight (this description is all by weight) is than being:
Cera Flava component: Oleum sesami component=1: 18～23
Described medicine components can be medicine components and/or its extract component, is divided into four groups, wherein:
First group is Radix Rehmanniae Preparata and Radix Rehmanniae component,
Second group is Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and Radix Arnebiae (Radix Lithospermi) component;
The 3rd group is Moschus and dry Exocarpium Citrulli component;
The 4th group is the Borneolum Syntheticum component;
Substrate: first group of component: second group of component: the 3rd group of component: the 4th component
1∶0.07～0.10∶0.07～0.10∶0.005～0.008∶0.007～0.010
Radix Rehmanniae Preparata component: Radix Rehmanniae component=1: 0.9～1.2
Radix Glycyrrhizae component: Radix Angelicae Sinensis component: Pericarpium Zanthoxyli component: Radix Arnebiae (Radix Lithospermi) component=1: 0.9～1.1: 0.4～0.6: 0.4～0.6.
Moschus component: dry Exocarpium Citrulli component=1: 12～15
The manufacture method of above-mentioned ointment for burns and scalds realizes by following measure:
(1) Oleum sesami is heated to 50 ℃ and adds Radix Rehmanniae Preparata and Radix Rehmanniae medicine when not seething with excitement, soak after 1 to 5 minute, continue to be warming up to boiling;
(2) Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and arnebia medicinal are joined in (1), treat 3 to 10 minutes after, add Cera Flava, under agitation, continue heating 3 to 10 minutes;
(3) Moschus and dry Exocarpium Citrulli medicine are joined in (2), under agitation continue heating 1 to 5 minute, remove medicinal residues, when treating that medicine temperature drop to 30 is ℃ to 80 ℃;
(4) the Borneolum Syntheticum medicine is joined in (3), stir.
The Cera Flava of described method: Oleum sesami=1: 18～23, Cera Flava+Oleum sesami: Radix Rehmanniae Preparata+Radix Rehmanniae: Radix Glycyrrhizae+Radix Angelicae Sinensis+Pericarpium Zanthoxyli+Radix Arnebiae (Radix Lithospermi): Moschus+dry Exocarpium Citrulli: Borneolum Syntheticum=1: 0.07～0.10: 0.07～0.10: 0.005～0.008: 0.007～0.010.
The Moschus of described method, Borneolum Syntheticum before the adding, grind earlier and are fine powder.
Radix Rehmanniae Preparata: the Radix Rehmanniae=1: 0.9～1.2
Radix Glycyrrhizae: Radix Angelicae Sinensis: Pericarpium Zanthoxyli: Radix Arnebiae (Radix Lithospermi)=1: 0.9～1.1: 0.4～0.6: 0.4～0.6;
Moschus: dry Exocarpium Citrulli=1: 12～15.
Ointment for burns and scalds of the present invention need not done any processing before having coating, do not need wind sheltering and environment sterilizing to handle behind the coating, medicine disappears to pain, and have hemostasis, antipruritic, detoxifcation, a removing heat from blood, putrefaction-removing granulation-promoting, cure fast and wound surface skin color of the leather is restored, no any misery in the treatment, cure rate is 100%.
The manufacture method of ointment for burns and scalds of the present invention, technology is simple, saves time, and has solved the drawback that prior art is interrupted production.
Ointment of the present invention is a medicine for external use, and the burn wound surface needn't be done any processing, directly coating, pain relieving in about about 1 minute behind the coating has aqueous liquid to discharge after the medication, the slightly white pus shape liquid of wound surface occurs to treat not arrange afterwards by water, white pus shape liquid stops the back incrustation, after several days, and decrustation, newborn skin grows, moist smooth, there is not any cicatrix, the skin color of the leather recovers gradually, general by summer, the skin color of the leather promptly restores fully.
Embodiment:
Example 1: ointment for burns and scalds: (being composition by weight down)
Cera Flava: Oleum sesami=1: 20
Cera Flava+Oleum sesami: Radix Rehmanniae Preparata+Radix Rehmanniae: Radix Glycyrrhizae+Radix Angelicae Sinensis+Pericarpium Zanthoxyli+Radix Arnebiae (Radix Lithospermi): Moschus+dry Exocarpium Citrulli: Borneolum Syntheticum=1: 0.08: 0.09: 0.005: 0.008
Radix Rehmanniae Preparata: the Radix Rehmanniae=1: 1
Radix Glycyrrhizae: Radix Angelicae Sinensis: Pericarpium Zanthoxyli: Radix Arnebiae (Radix Lithospermi)=1: 1: 0.5: 0.5
Moschus: dry Exocarpium Citrulli=1: 13
Example 2, ointment for burns and scalds
Cera Flava: Oleum sesami=1: 23
Cera Flava+Oleum sesami: Radix Rehmanniae Preparata+Radix Rehmanniae: Radix Glycyrrhizae+Radix Angelicae Sinensis+Pericarpium Zanthoxyli+Radix Arnebiae (Radix Lithospermi): Moschus+dry Exocarpium Citrulli: Borneolum Syntheticum=1: 0.07: 0.10: 0.007: 0.007
Radix Rehmanniae Preparata: the Radix Rehmanniae=1: 1.2
Radix Glycyrrhizae: Radix Angelicae Sinensis: Pericarpium Zanthoxyli: Radix Arnebiae (Radix Lithospermi)=1: 0.9: 0.6: 0.4
Moschus: dry Exocarpium Citrulli=1: 15.
The manufacture method of example 3, ointment for burns and scalds:
800 gram Oleum sesami are heated to 60 ℃, add the Radix Rehmanniae Preparata and the Radix Rehmanniae totally 70 grams (respectively being 35 grams), soak the follow-up continuous boiling that is warming up in 3 minutes;
(2) 80 gram Radix Glycyrrhizaes, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and Radix Arnebiae (Radix Lithospermi) (25 gram Radix Glycyrrhizaes, 25 gram Radix Angelicae Sinensis, 15 gram Pericarpium Zanthoxylies, 15 gram Radix Arnebiae (Radix Lithospermi)s) are joined in (1), treat 6 minutes after, add 36 gram Cera Flava, heating while stirring, treat 7 minutes after;
(3) Moschus (fine-powdered) and dry Exocarpium Citrulli 6 grams (0.4 gram Moschus, 5.5 gram dry Exocarpium Citrulli) are joined in (2), heating while stirring is after 4 minutes, after the removal medicinal residues treat that temperature is reduced to 70 ℃;
(4) Borneolum Syntheticum that 8 grams are ground to fine powder joins in (3), and stirring gets final product.
The manufacture method of example 4, ointment for burns and scalds:
(1) 800 gram Oleum sesami is heated to 80 ℃, adds the Radix Rehmanniae Preparata and the Radix Rehmanniae totally 65 grams (Radix Rehmanniae Preparata 30 grams, the Radix Rehmanniae 35 grams), soak the follow-up continuous boiling that is warming up in 5 minutes;
(2) 76 gram Radix Glycyrrhizaes, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and Radix Arnebiae (Radix Lithospermi) (25 gram Radix Glycyrrhizaes, 23 gram Radix Angelicae Sinensis, 13 gram Pericarpium Zanthoxylies, 15 gram Radix Arnebiae (Radix Lithospermi)s) are joined in (1), treat 10 minutes after, add 45 gram Cera Flava, heating while stirring, treat 5 minutes after;
(3) Moschus (fine-powdered) and dry Exocarpium Citrulli 7 grams (0.5 gram Moschus, 6.5 gram dry Exocarpium Citrulli) are joined in (2), heating while stirring after 1 minute, is removed medicinal residues, treat that temperature is reduced to 30 ℃ after.
(4) Borneolum Syntheticum that 7 grams are ground to fine powder joins in (3), stirs.
Claims (5)
1, ointment for burns and scalds contains substrate and medicine components, it is characterized in that (all by weight):
(1) described substrate component is Cera Flava component and Oleum sesami component, Cera Flava component: Oleum sesami component=1: 18～23;
(2) described medicine components can be medicine components and/or its extract component, wherein:
First group is Radix Rehmanniae Preparata and Radix Rehmanniae component;
Second group is Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and Radix Arnebiae (Radix Lithospermi) component;
The 3rd group is Moschus and dry Exocarpium Citrulli component;
The 4th group is the Borneolum Syntheticum component;
Substrate: first group of component: second group of component: the 3rd group of component: the 4th group of component
1∶0.07～0.1∶0.07～0.1∶0.005～0.008∶0.007～0.010
2, ointment for burns and scalds according to claim 1 is characterized in that:
Radix Rehmanniae Preparata component: Radix Rehmanniae component=1: 0.9～1.2
Radix Glycyrrhizae component: Radix Angelicae Sinensis component: Pericarpium Zanthoxyli component: Radix Arnebiae (Radix Lithospermi) component=1: 0.9～1.1: 0.4～0.6: 0.4～0.6;
Moschus component: dry Exocarpium Citrulli component=1: 12～15.
3, make the method for the described ointment for burns and scalds of claim 1, it is characterized in that:
(1) Oleum sesami is heated to 50 ℃ and adds Radix Rehmanniae Preparata and Radix Rehmanniae medicine when not seething with excitement, soak after 1～5 minute, continue to be warming up to boiling;
(2) Radix Glycyrrhizae, Radix Angelicae Sinensis, Pericarpium Zanthoxyli and arnebia medicinal are joined in (1), treat 3 to 10 minutes after, add Cera Flava, under agitation, continue heating 3 to 10 minutes.
(3) Moschus and dry Exocarpium Citrulli medicine are joined in (2), under agitation continue heating 1 to 5 minute, remove medicinal residues, when treating that medicine temperature drop to 30 is ℃ to 80 ℃;
(4) the Borneolum Syntheticum medicine is joined in (3), stir.
4, the method for manufacturing ointment for burns and scalds according to claim 3 is characterized in that
Cera Flava: Oleum sesami=1: 18～23
Cera Flava+Oleum sesami: Radix Rehmanniae Preparata+Radix Rehmanniae: Radix Glycyrrhizae+Radix Angelicae Sinensis+Pericarpium Zanthoxyli+Radix Arnebiae (Radix Lithospermi): Moschus+dry Exocarpium Citrulli: Borneolum Syntheticum=1: 0.07～0.10: 0.07～0.10: 0.005～0.008: 0.007～0.010;
5, the method for manufacturing ointment for burns and scalds according to claim 4 is characterized in that
Radix Rehmanniae Preparata: the Radix Rehmanniae=1: 0.9～1.2
Radix Glycyrrhizae: Radix Angelicae Sinensis: Pericarpium Zanthoxyli: Radix Arnebiae (Radix Lithospermi)=1: 0.9～1.1: 0.4～0.6: 0.4～0.6,
Moschus: dry Exocarpium Citrulli=1: 12～15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93111265A CN1095921A (en) | 1993-05-31 | 1993-05-31 | Ointment for burns and scalds and manufacture method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93111265A CN1095921A (en) | 1993-05-31 | 1993-05-31 | Ointment for burns and scalds and manufacture method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN1095921A true CN1095921A (en) | 1994-12-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93111265A Pending CN1095921A (en) | 1993-05-31 | 1993-05-31 | Ointment for burns and scalds and manufacture method thereof |
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| CN (1) | CN1095921A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612245B (en) * | 2008-06-26 | 2011-08-31 | 姚自功 | Burn ointment |
| CN102429988A (en) * | 2010-09-29 | 2012-05-02 | 任柄文 | Traditional Chinese medicine preparation used for burn |
| CN110201079A (en) * | 2019-07-10 | 2019-09-06 | 张恒 | A kind of Chinese materia medica preparation and preparation method of burn and scald |
-
1993
- 1993-05-31 CN CN93111265A patent/CN1095921A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612245B (en) * | 2008-06-26 | 2011-08-31 | 姚自功 | Burn ointment |
| CN102429988A (en) * | 2010-09-29 | 2012-05-02 | 任柄文 | Traditional Chinese medicine preparation used for burn |
| CN110201079A (en) * | 2019-07-10 | 2019-09-06 | 张恒 | A kind of Chinese materia medica preparation and preparation method of burn and scald |
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