CN1839898A - Scar-free wet ointment for scald and burn and its preparation method - Google Patents
Scar-free wet ointment for scald and burn and its preparation method Download PDFInfo
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- CN1839898A CN1839898A CN 200510016837 CN200510016837A CN1839898A CN 1839898 A CN1839898 A CN 1839898A CN 200510016837 CN200510016837 CN 200510016837 CN 200510016837 A CN200510016837 A CN 200510016837A CN 1839898 A CN1839898 A CN 1839898A
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Abstract
The invention relates to a scar-free wet ointment for scald and burn and its preparation method, wherein the raw materials comprise (by weight ratio) sesame oil 30-65%, 35-70% of calcium hydroxide aqueous solution with a concentration of 2-3%, and the preparing process comprises mixing, stirring, passing through colloid grinder to obtain ointment, finally tabulating and sterilizing.
Description
Technical field
The present invention relates to a kind of scar-free wet salve for treating burn and scald and preparation method.
Background technology
In prior art, burn and scald is common unexpected injury, and medicine for external use is a medicine commonly used.This type of medicament categories is various, and especially the patent application medicine also reaches hundreds of, and prescription is different, and curative effect is different.On July 24th, 2002 disclose a kind of name as the Chinese invention patent ublic specification of application and be called " Chinese medicine preparation of treatment burn and scald and preparation method thereof " patent application medicine, number of patent application 01141347.6, its content are by Cacumen Platycladi, Herba Artemisiae Anomalae, Radix Salviae Miltiorrhizae, Radix gynurae segeti root, Herba Violae, Borneolum Syntheticum and an amount of made a kind of pasty state externally dressing of Oleum sesami.Its shortcoming is the prescription complexity, the cost height.
Summary of the invention
The objective of the invention is provides a kind of prescription simple at above-mentioned deficiency, with low cost, evident in efficacy, rational scar-free wet salve for treating burn and scald of technology and preparation method.
Technical solution of the present invention is: the scar-free wet salve for treating burn and scald comprises that following raw materials by weight percent makes: Oleum sesami 30-65%, concentration is the calcium hydroxide aqueous solution 35-70% of 2%-3%.Also can add lanoline 0-30%, or carbomer 0-3%.Haidian, carbomer HYI-941 Beijing can imperial Fine Chemical Works production.Calcium hydroxide aqueous solution is the mixed liquor of calcium hydroxide and distilled water, leaves standstill more than 24 hours, gets its supernatant.
The Sheng Nong's herbal classic record: the Oleum sesami sweet in the mouth is flat, and main damaging the spleen and stomach is empty wins, mend in five, and physical strength profiting, longue meat is filled out the marrow brain, and clothes are made light of one's life by commiting suicide and are not forgotten for a long time.Modern pharmacological research shows: the Main Ingredients and Appearance of Oleum sesami is unsaturated fatty acids such as linoleic acid, Palmic acid.Oleum sesami is rich in calcium, ferrum, unsaturated fatty acid, has abundant vitamin A, and E and B, especially vitamin E are natural inhibitors, have antioxidation.Contain unsaturated fatty acid in the Oleum sesami to the human body beneficial, the more important thing is the oleic acid composition that contains in the Oleum sesami, confirmed that by medical science diseases such as the ulcer of inhibition, asthma are arranged, have the skin of preventing matter and worsen, improve the effect of immunity, the effect of the thermal detoxification of dispelling, relieving constipation granulation promoting, vessel softening is arranged.In addition, the contained active ingredient of Oleum sesami all has inhibitory action for wrinkle, black speck, scaly dry skin etc.Oleum sesami can impel muscle growth, and is effective in cure for chronic neuritis, peripheral nerve paralysis, is used for the treatment of thrombocytopenic purpura and the hemorrhagic illness has certain effect.The pure Oleum sesami of record can also be widely used in and make emollient and medicinal components carrier in the external preparation for skin medicine in U.S.'s shellfish thunder " oil chemistry and technology " book.Calcium hydroxide aqueous solution has the effect of astringing to arrest bleeding, inhibiting bacteria and diminishing inflammation.Pathogen there is stronger killing action.Specifically be 1, can lower the permeability of blood capillary, inflammatory swelling is had preventive and therapeutic effect.2, can increase the concentration of calcium ion in the blood, make the blood vessel densification, prevent that blood plasma from oozing out, promote blood coagulation, and the direct contract skin blood vessel of energy, anastalsis is arranged.3, can reduce oozing out of mucosal surface secretions, astriction is arranged.4, the comprehensive various acids of energy absorb poison.5, have that dispersing swelling and dissipating binds, hemostasis are held back wet, anti-inflammatory analgetic, the erosion wart is treated the skin ulcer effect.Lanoline: having and preserve moisture and the skin care effect, is the softening agent and the wetting agent of skin.The general carbomer gel agent by name of carbomer promptly can form full-bodied gel under very low concentration, multiple use is arranged in medicament, as can be used as framework material of thickening agent, suspending agent, gel-type vehicle, bioadhesive material, control slow releasing agent etc.The present invention's technology routinely also can add a little adjuvants, as ethyl p-hydroxybenzoate antiseptic or the like.
The preparation method of described treatment burn and scald medicine is: get calcium hydroxide aqueous solution, Oleum sesami and put fully to mix in the same container and stir, allow it carry out emulsion reaction, generates new emulsion, colloid mill get ointment, sterilize after the tubulature.
Or: 1, get calcium hydroxide aqueous solution, Oleum sesami and put fully to mix in the same container and stir, allow it carry out emulsion reaction, generate new emulsion.2, get lanoline and put in the container, heating in water bath makes its dissolving, heating-up temperature 36-80 ℃.3, above-mentioned emulsion is inserted in the container that the lanoline solute is housed, stir, cross colloid mill and get ointment, sterilize after the tubulature.
Or: get calcium hydroxide aqueous solution, Oleum sesami and put fully to mix in the same container and stir, allow it carry out emulsion reaction, generates new emulsion, add, be mixed with the carbomer behind the dissolved in distilled water, colloid mill get ointment, sterilize after the tubulature.
Usage: external.Be applied to empyrosis wound surface (the about 1mm of thickness), changed dressings once in every 4-6 hour, must soak into ointment with aseptic cotton or antiseptic gauze before changing dressings wipes medicine on the wound surface and liquefaction extractum away, expose topical agent, the big person of wound surface can be applied to ointment wound surface (about 1-1.5mm), again antiseptic gauze is soaked into ointment, spread on then on the wound surface, cement with the health adhesive plaster and get final product.Usually the I degree is burnt and can be cured in general 3-5 days; II degree burn generally can be cured at 7-15 days; III degree burn can be cured in 15 days-1 month.
Function cures mainly: astringing to arrest bleeding, Repercusion analgesia, anti-inflammation, removing the necrotic tissue and promoting granulation.Be used for the treatment of various burn and scald, more the no cicatrix in back.
Advantage of the present invention is: 1, through 256 actual uses of patient, cure rate is more than 98%, and effect is very obvious, has short treating period, instant effect, cure rate height, the more seamless characteristics in back.2, prescription is simple, and is with low cost, and raw material is easy to get, safe in utilization.
Below in conjunction with embodiment the present invention is described in further detail.
The specific embodiment
Embodiment 1
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 35%, concentration are 2% calcium hydroxide aqueous solution 65%.
Embodiment 2
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 30%, concentration are 2.5% calcium hydroxide aqueous solution 70%.
Embodiment 3
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 50%, concentration are 3% calcium hydroxide aqueous solution 50%.
Embodiment 4
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 30%, concentration are 2% calcium hydroxide aqueous solution 60%, lanoline 10%.
Embodiment 5
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 40%, concentration are 2.5% calcium hydroxide aqueous solution 40%, lanoline 20%.
Embodiment 6
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 35%, concentration are 3% calcium hydroxide aqueous solution 35%, lanoline 30%.
Embodiment 7
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 50%, concentration are 2% calcium hydroxide aqueous solution 49%, carbomer 1%.
Embodiment 8
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 35%, concentration are 2.5% calcium hydroxide aqueous solution 63%, carbomer 2%.
Embodiment 9
The scar-free wet salve for treating burn and scald is made by following raw materials by weight percent: Oleum sesami 30%, concentration are 3% calcium hydroxide aqueous solution 67%, carbomer 3%.
Embodiment 10
The preparation method of scar-free wet salve for treating burn and scald: get calcium hydroxide aqueous solution 600g, Oleum sesami 400g and put mixing stirring in the same container, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 11
The preparation method of scar-free wet salve for treating burn and scald: a, get 2% calcium hydroxide aqueous solution 600g, Oleum sesami 300g put mix in the same container stir mixed liquor; B, get lanoline 100g and put in the container, heating in water bath makes its dissolving, heating-up temperature 36-80 ℃; C, the mixed liquor in a step is inserted in the container that the lanoline solute is housed, stir, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 12
The preparation method of scar-free wet salve for treating burn and scald: a, get 2.5% calcium hydroxide aqueous solution 400g, Oleum sesami 400g put mix in the same container stir mixed liquor; B, get lanoline 200g and put in the container, heating in water bath makes its dissolving, heating-up temperature 36-80 ℃; C, the mixed liquor in a step is inserted in the container that the lanoline solute is housed, stir, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 13
The preparation method of scar-free wet salve for treating burn and scald: a, get 3% calcium hydroxide aqueous solution 350g, Oleum sesami 350g put mix in the same container stir mixed liquor; B, get lanoline 300g and put in the container, heating in water bath makes its dissolving, heating-up temperature 36-80 ℃; C, the mixed liquor in a step is inserted in the container that the lanoline solute is housed, stir, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 14
The preparation method of scar-free wet salve for treating burn and scald: get 2% calcium hydroxide aqueous solution 400g, Oleum sesami 500g and put mixing stirring in the same container; With distilled water 90g dissolving carbomer 10g, be mixed, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 15
The preparation method of scar-free wet salve for treating burn and scald: get 2.5% calcium hydroxide aqueous solution 550g, Oleum sesami 350g and put mixing stirring in the same container; With distilled water 80g dissolving carbomer 20g, be mixed, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Embodiment 16
The preparation method of scar-free wet salve for treating burn and scald: get 3% calcium hydroxide aqueous solution 600g, Oleum sesami 300g and put mixing stirring in the same container; With distilled water 70g dissolving carbomer 30g, be mixed, cross colloid mill and get the nearly 1000g of ointment, sterilize after the tubulature.
Claims (6)
1, a kind of scar-free wet salve for treating burn and scald, it is characterized in that comprising that following raw materials by weight percent makes: Oleum sesami 30-65%, concentration is the calcium hydroxide aqueous solution 35-70% of 2%-3%.
2, according to the described scar-free wet salve for treating burn and scald of claim 1, it is characterized in that containing lanoline 0-30%.
3, according to the described scar-free wet salve for treating burn and scald of claim 1, it is characterized in that containing carbomer 0-3%.
4, a kind of preparation method of the salve for treating burn and scald of scar-free wet according to claim 1 is characterized in that: get calcium hydroxide aqueous solution, Oleum sesami and put to mix in the same container and stir, cross colloid mill and get ointment, sterilize after the tubulature.
5, a kind of preparation method as scar-free wet salve for treating burn and scald as described in the claim 2 is characterized in that: a, get calcium hydroxide aqueous solution, Oleum sesami put mix in the same container stir mixed liquor; B, get lanoline and put in the container, heating in water bath makes its dissolving, heating-up temperature 36-80 ℃; C, the mixed liquor in a step is inserted in the container that the lanoline solute is housed, stir, cross colloid mill and get ointment, sterilize after the tubulature.
6, a kind of preparation method as scar-free wet salve for treating burn and scald as described in the claim 3 is characterized in that: get calcium hydroxide aqueous solution, Oleum sesami is put to mix in the same container and stirred; The carbomer of adding after with dissolved in distilled water is mixed, and crosses colloid mill and gets ointment, sterilizes after the tubulature.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510016837 CN1839898A (en) | 2005-05-31 | 2005-05-31 | Scar-free wet ointment for scald and burn and its preparation method |
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| CN 200510016837 CN1839898A (en) | 2005-05-31 | 2005-05-31 | Scar-free wet ointment for scald and burn and its preparation method |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579483A (en) * | 2012-03-01 | 2012-07-18 | 张家富 | Emulsion liniment for curing mild burn and preparation method thereof |
| CN103948655A (en) * | 2014-05-25 | 2014-07-30 | 宜兴市人民医院 | Special-effect external emulsion for treating burns due to hot-liquid or fire and simple preparation method thereof |
| CN108079061A (en) * | 2018-02-09 | 2018-05-29 | 白金肤人生物科技（深圳）有限公司 | A kind of pharmaceutical composition and preparation method and application |
| CN108210543A (en) * | 2018-03-28 | 2018-06-29 | 周代明 | It is a kind of to be used to treat composition of burn and scald and preparation method thereof |
| WO2020012136A1 (en) | 2018-07-13 | 2020-01-16 | Gifrer Barbezat | Alkaline oleo-liniment |
-
2005
- 2005-05-31 CN CN 200510016837 patent/CN1839898A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579483A (en) * | 2012-03-01 | 2012-07-18 | 张家富 | Emulsion liniment for curing mild burn and preparation method thereof |
| CN103948655A (en) * | 2014-05-25 | 2014-07-30 | 宜兴市人民医院 | Special-effect external emulsion for treating burns due to hot-liquid or fire and simple preparation method thereof |
| CN108079061A (en) * | 2018-02-09 | 2018-05-29 | 白金肤人生物科技（深圳）有限公司 | A kind of pharmaceutical composition and preparation method and application |
| CN108210543A (en) * | 2018-03-28 | 2018-06-29 | 周代明 | It is a kind of to be used to treat composition of burn and scald and preparation method thereof |
| WO2020012136A1 (en) | 2018-07-13 | 2020-01-16 | Gifrer Barbezat | Alkaline oleo-liniment |
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