CN108685766A - A kind of antiallergic Face-protecting mask liquid and preparation method thereof - Google Patents

A kind of antiallergic Face-protecting mask liquid and preparation method thereof Download PDF

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Publication number
CN108685766A
CN108685766A CN201810721381.0A CN201810721381A CN108685766A CN 108685766 A CN108685766 A CN 108685766A CN 201810721381 A CN201810721381 A CN 201810721381A CN 108685766 A CN108685766 A CN 108685766A
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China
Prior art keywords
mask liquid
antiallergic
protecting mask
face
preparation
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Pending
Application number
CN201810721381.0A
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Chinese (zh)
Inventor
刘铸
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China Bio Technology Development (shenzhen) Co Ltd
Guangzhou Yin Lu Biotechnology Co Ltd
Original Assignee
China Bio Technology Development (shenzhen) Co Ltd
Guangzhou Yin Lu Biotechnology Co Ltd
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Application filed by China Bio Technology Development (shenzhen) Co Ltd, Guangzhou Yin Lu Biotechnology Co Ltd filed Critical China Bio Technology Development (shenzhen) Co Ltd
Priority to CN201810721381.0A priority Critical patent/CN108685766A/en
Publication of CN108685766A publication Critical patent/CN108685766A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of antiallergic Face-protecting mask liquid, include following component according to the weight percentage of raw materials:Sodium Hyaluronate 0.05~0.2%, carboxymethylchitosan 0.05~0.2%, allantoin 0.1~0.3%, composite humectant 6~8%, preservative 2~3%, phosphatidase 1 .5~3%, silicone oil 2~5%, emulsifier 0.5~1%, glycerine 4~6%, butanediol 2~5%, deionized water surplus.The present invention has lasting antiallergic maintenance performance, and system stability is good, while having the effects that reparation, anti-inflammatory, antibacterial to skin, the long-term daily nursing especially suitable for sensibility skin.Simple for process the invention also discloses the preparation method of the facial mask liquid, controllability is strong, is conducive to large-scale industrial production.

Description

A kind of antiallergic Face-protecting mask liquid and preparation method thereof
Technical field
The present invention relates to daily skin care field, more particularly to a kind of facial mask liquid.
Background technology
With the increasingly raising of people's living standard, skin care item have gradually become indispensable daily in modern life One of product.Meanwhile because of the influence in each face of each side such as food, environment, medical treatment, modern's sensibility skin proportion constantly increases Add.Sensibility skin is impaired because of skin barrier, it is difficult to some functional skin nursings is carried out, such as whitening, crease-resistant, contraction hair Hole, disappear acne etc., so that the people with sensibility skin can not obtain required skin nursing.
Chitosan is a kind of bioactive substance extracted from the discarded crust such as shrimp, crab, by chitin in highly basic Property under the conditions of carry out a kind of important derivative for being formed after deacetylation, chemical name is Chitosan (1-4) -2- Amino-B-D glucose, intramolecular exist simultaneously free amino and hydroxyl, have special physiological activity, especially anti- In terms of bacterium, chitosan anti-bacteria spectrum is wide, not only effective to various bacteria, and can inhibit the growth and breeding of many fungies.It is special Some straight chain polycation structures, film forming invest keratin on lipoids, not only stablized at high operating temperatures, but also have certain water Divide regulatory function.Chitosan has excellent water absorbency and water retentivity, and be added in skin care item not only can provide battalion to skin A point such as collagen is formed, but also ceramide in the dry and cracked seam that epidermis generates and in epidermal lipid film layer can be filled and make With final and epidermis length is integral, it can also stimulate the reproduction speed for accelerating epidermal cell, to reach delaying senility, modification The effect of beauty.
However, the moistening effect of the existing skin care item added with chitosan is still to be improved.
Invention content
It is an object of the invention in view of the above shortcomings of the prior art, provide a kind of antiallergic Face-protecting mask liquid, carry simultaneously For the preparation method of the facial mask liquid.
The technical solution used in the present invention is:A kind of antiallergic Face-protecting mask liquid includes according to the weight percentage of raw materials Following component:
The present invention regard carboxymethylchitosan and Sodium Hyaluronate compounding as antiallergic maintenance principle active component, together When be equipped with a certain amount of composite humectant, not only there is lasting antiallergic maintenance and humectant energy, while also greatly improving The stability of the composition.
As being further improved for said program, the molecular weight of the carboxymethylchitosan is 15000~ 20000.Specifically, the present invention is defined the molecular weight of carboxymethylchitosan, it is made to be compounded with Sodium Hyaluronate There is efficiently synergistic effect afterwards, help to form stable moisture film in skin surface, and the moisture film is with good lasting Performance is conducive to the performance of keeping humidity for improving the facial mask liquid.
As being further improved for said program, the composite humectant by NMF-50, r-PGA and ethoxy urea compounding and At.Specifically, composite humectant of the invention has many advantages, such as that additive amount is few, side effect is low, non-toxic.
As being further improved for said program, the preservative is methyl hydroxybenzoate.Specifically, preservative of the invention tool Have the advantages that additive amount is few, side effect is low, non-toxic.
As being further improved for said program, the emulsifier is EMT-10, is had in the facial mask liquid system good Good dispersion performance.
A kind of preparation method of antiallergic Face-protecting mask liquid as described above, it is characterised in that include the following steps:
First butanediol, glycerine, silicone oil and phosphatide are add to deionized water and are heated to according to the weight percentage of raw materials 65~75 DEG C of dissolvings stir evenly;
40~50 DEG C are cooled to, Sodium Hyaluronate is added, carboxymethylchitosan, allantoin, composite humectant, prevents Rotten agent and emulsifier, stir evenly and get product.
The beneficial effects of the invention are as follows:The present invention has lasting high moisturizing and antiallergic maintenance performance, and system stability Well, while to skin have the effects that reparation, anti-inflammatory, antibacterial, the long-term daily nursing especially suitable for sensibility skin.
The preparation method of the present invention is simple for process, and controllability is strong, is conducive to large-scale industrial production.
Specific implementation mode
The present invention is specifically described with reference to embodiment, in order to technical field personnel to the present invention Understand.It is necessary to it is emphasized that embodiment is only intended to, the present invention will be further described herein, should not be understood as to this The limitation of invention protection domain, fields person skilled in the art, the non-intrinsically safe that the present invention is made according to foregoing invention content The modifications and adaptations of property, should still fall within protection scope of the present invention.Mentioned raw materials following simultaneously are unspecified, are Commercial product;The processing step or preparation method not referred in detail be processing step known to a person skilled in the art or Preparation method.
Embodiment 1
A kind of antiallergic Face-protecting mask liquid includes following component according to the weight percentage of raw materials:
Wherein, the molecular weight of the carboxymethylchitosan is 15000~20000;The composite humectant by NMF-50, r-PGA and ethoxy urea compound.
Preparation method:
First butanediol, glycerine, silicone oil and phosphatide are add to deionized water and are heated to according to the weight percentage of raw materials 65 DEG C of dissolvings stir evenly;
50 DEG C are cooled to, Sodium Hyaluronate, carboxymethylchitosan, allantoin, composite humectant, preservative is added And emulsifier, it stirs evenly, obtains 1 finished product of embodiment.
Daily facial mask shield by 1 finished product of gained embodiment for 100 volunteers (subject) with sensibility skin Reason, cooperation face paper applies primary after every night face cleaning, and the tested period is 2 months.Through feedback, 100 volunteers were testing There is no the bad phenomenon of sensibility skin in journey, wherein there is the volunteer of small pox to obtain the good acne effect that disappears on the face, And moisturizing duration average out to is for 24 hours after having applied 1 finished product of embodiment.
Embodiment 2
A kind of antiallergic Face-protecting mask liquid includes following component according to the weight percentage of raw materials:
Wherein, the molecular weight of the carboxymethylchitosan is 15000~20000;The composite humectant by NMF-50, r-PGA and ethoxy urea compound.
Preparation method:
First butanediol, glycerine, silicone oil and phosphatide are add to deionized water and are heated to according to the weight percentage of raw materials 75 DEG C of dissolvings stir evenly;
40 DEG C are cooled to, Sodium Hyaluronate, carboxymethylchitosan, allantoin, composite humectant, preservative is added And emulsifier, it stirs evenly, obtains 2 finished product of embodiment.
Daily facial mask shield by 2 finished product of gained embodiment for 100 volunteers (subject) with sensibility skin Reason, cooperation face paper applies primary after every night face cleaning, and the tested period is 2 months.Through feedback, 100 volunteers were testing There is no the bad phenomenon of sensibility skin in journey, wherein there is the volunteer of small pox to obtain the good acne effect that disappears on the face, And moisturizing duration average out to is for 24 hours after having applied 2 finished product of embodiment.
Embodiment 3
A kind of antiallergic Face-protecting mask liquid includes following component according to the weight percentage of raw materials:
Wherein, the molecular weight of the carboxymethylchitosan is 15000~20000;The composite humectant by NMF-50, r-PGA and ethoxy urea compound.
Preparation method:
First butanediol, glycerine, silicone oil and phosphatide are add to deionized water and are heated to according to the weight percentage of raw materials 70 DEG C of dissolvings stir evenly;
45 DEG C are cooled to, Sodium Hyaluronate, carboxymethylchitosan, allantoin, composite humectant, preservative is added And emulsifier, it stirs evenly, obtains 3 finished product of embodiment.
Daily facial mask shield by 3 finished product of gained embodiment for 100 volunteers (subject) with sensibility skin Reason, cooperation face paper applies primary after every night face cleaning, and the tested period is 2 months.Through feedback, 100 volunteers were testing There is no the bad phenomenon of sensibility skin in journey, wherein there is the volunteer of small pox to obtain the good acne effect that disappears on the face, And moisturizing duration average out to is for 24 hours after having applied 3 finished product of embodiment.
Above-described embodiment is the preferred embodiment of the present invention, it is all with similar technique of the invention and made by equivalence changes, The protection category of the present invention should all be belonged to.

Claims (6)

1. a kind of antiallergic Face-protecting mask liquid, it is characterised in that include following component according to the weight percentage of raw materials:
2. a kind of antiallergic Face-protecting mask liquid according to claim 1, it is characterised in that:The carboxymethylchitosan Molecular weight be 15000~20000.
3. a kind of antiallergic Face-protecting mask liquid according to claim 1, it is characterised in that:The composite humectant is by NMF- 50, r-PGA and ethoxy urea compound.
4. a kind of antiallergic Face-protecting mask liquid according to claim 1, it is characterised in that:The preservative is methyl hydroxybenzoate.
5. a kind of antiallergic Face-protecting mask liquid according to claim 1, it is characterised in that:The emulsifier is EMT-10.
6. a kind of preparation method of such as Claims 1 to 5 any one of them antiallergic Face-protecting mask liquid, it is characterised in that including such as Lower step:
According to the weight percentage of raw materials first be add to deionized water butanediol, glycerine, silicone oil and phosphatide and it is heated to 65~ 75 DEG C of dissolvings stir evenly;
40~50 DEG C are cooled to, Sodium Hyaluronate, carboxymethylchitosan, allantoin, composite humectant, preservative is added And emulsifier, it stirs evenly and gets product.
CN201810721381.0A 2018-07-03 2018-07-03 A kind of antiallergic Face-protecting mask liquid and preparation method thereof Pending CN108685766A (en)

Priority Applications (1)

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CN201810721381.0A CN108685766A (en) 2018-07-03 2018-07-03 A kind of antiallergic Face-protecting mask liquid and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810721381.0A CN108685766A (en) 2018-07-03 2018-07-03 A kind of antiallergic Face-protecting mask liquid and preparation method thereof

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106727164A (en) * 2017-02-16 2017-05-31 中山卡丝生物科技有限公司 A kind of moisture-keeping composition and its preparation method and application
KR20170099656A (en) * 2016-02-24 2017-09-01 주식회사 엘지생활건강 Cosmetic compositions for moisturizing
CN107648057A (en) * 2017-10-21 2018-02-02 诺斯贝尔化妆品股份有限公司 Biofibre facial mask is repaired in a kind of long-acting moisturizing
CN108175727A (en) * 2017-12-28 2018-06-19 广州蜜妆生物科技有限公司 A kind of anti-acne print Face-protecting mask patch and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170099656A (en) * 2016-02-24 2017-09-01 주식회사 엘지생활건강 Cosmetic compositions for moisturizing
CN106727164A (en) * 2017-02-16 2017-05-31 中山卡丝生物科技有限公司 A kind of moisture-keeping composition and its preparation method and application
CN107648057A (en) * 2017-10-21 2018-02-02 诺斯贝尔化妆品股份有限公司 Biofibre facial mask is repaired in a kind of long-acting moisturizing
CN108175727A (en) * 2017-12-28 2018-06-19 广州蜜妆生物科技有限公司 A kind of anti-acne print Face-protecting mask patch and preparation method thereof

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Application publication date: 20181023

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