CN108654141A - A kind of platelet rich plasma preparation facilities - Google Patents

A kind of platelet rich plasma preparation facilities Download PDF

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Publication number
CN108654141A
CN108654141A CN201810583443.6A CN201810583443A CN108654141A CN 108654141 A CN108654141 A CN 108654141A CN 201810583443 A CN201810583443 A CN 201810583443A CN 108654141 A CN108654141 A CN 108654141A
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China
Prior art keywords
compression bar
preparation facilities
tube body
chamber
rich plasma
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CN201810583443.6A
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CN108654141B (en
Inventor
张旭波
卓清山
张鹏云
汪宇
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NINGBO HUAKERUN BIOTECHNOLOGY CO Ltd
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NINGBO HUAKERUN BIOTECHNOLOGY CO Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02Separation of non-miscible liquids
    • B01D17/0217Separation of non-miscible liquids by centrifugal force

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  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention relates to a kind of platelet rich plasma preparation facilities, belong to medical instruments field.The present invention provides a kind of platelet rich plasma preparation facilities, preparation facilities includes:Tube body, compression bar;Tube body top end opening bottom end closure;The lower edge of compression bar is slided along the inner wall sealing of tube body;Tubular body includes first chamber and second chamber;Compression bar is hollow stem, and the side wall of compression bar is equipped with compression bar side port, and compression bar side port is connected to first chamber and second chamber.The present invention can either avoid the vibrations to platelet rich plasma in preparation process, other blood constituents such as red blood cell can be prevented to be mixed into platelet rich plasma again, operation difficulty can also be reduced, and whole operation process of the present invention carries out in same container, and guarantee prepares the high quality of the high efficiency of platelet rich plasma process and the platelet rich plasma of preparation.

Description

A kind of platelet rich plasma preparation facilities
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of platelet rich plasma preparation facilities.
Background technology
Blood is mainly made of haemocyte, blood platelet, blood plasma, and wherein blood platelet can discharge a variety of growth factor promotion groups Knit regeneration and reparation.By being centrifuged to blood, the ingredient of different specific weight is separated into blood plasma, blood platelet and haemocyte successively. The thrombocyte plasma of concentration can therefrom be separated by sequence of operations, i.e. platelet rich plasma (Platelet-Rich Plasma,PRP).In the blood plasma in addition to high concentration blood platelet, also contain high concentration leucocyte and fibrin.Leucocyte can be prevented It only infects, fibrin can build the three-dimensional structure needed for tissue repair.A large amount of basic research and clinical test are proved PRP can remarkably promote the reparation of bone tissue and soft tissue.Since PRP is from self, safely and effectively, it is applied to bone The fields such as section, Oral and Maxillofacial Surgery, shaping, beauty, sports medical science.
Using existing platelet rich plasma preparation facilities when preparing platelet rich plasma, there are the following problems:It is open Preparation system be easy by outside contamination;There are being shifted between more containers, increases blood platelet and be contaminated and activate probability;It needs to carry out Red blood cell layer removes operation, complicated for operation, and the platelet rich plasma blood platelet acquisition rate prepared is easily by operator's proficiency It influences, it is difficult to which blood platelet is concentrated into high concentration.
Invention content
In view of above-mentioned analysis, the present invention is intended to provide a kind of platelet rich plasma preparation facilities, to solve existing set Prepare insufficient, the complicated for operation and insufficient safety problem of standby platelet rich plasma quality.
The purpose of the present invention is mainly achieved through the following technical solutions:
An embodiment provides a kind of platelet rich plasma preparation facilities, preparation facilities includes:Tube body, pressure Bar;Tube body top end opening bottom end closure, tube body include first chamber and second chamber;The inner wall sealing of the lower end edge tube body of compression bar Sliding, compression bar are hollow stem, and the side wall of compression bar is equipped with compression bar side port, and compression bar side port is connected to first chamber and second chamber.
In one embodiment of the present of invention, preparation facilities is additionally provided with pushing structure, and pushing structure is arranged on the top of compression bar.
In one embodiment of the present of invention, compression bar further includes interior bar, and interior bar is hollow stem, and is connect with pushing structure;It is interior Rod set is located in compression bar, and interior bar carries out axial direction and/or circumferential movement along the inner surface of compression bar, and when movement keeps sealing state; The side wall of compression bar is equipped with interior bar side port, and interior bar side port is corresponding with the position of compression bar side port.
In one embodiment of the present of invention, compression bar includes the cylindrical portion being from top to bottom arranged and expansion mouth, and interior bar is set in In cylindrical portion;The sectional dimension of expansion mouth from top to bottom gradually increases.
In one embodiment of the present of invention, tube body includes from top to bottom:Thick portion, transition part and thin portion, the section ruler of thick portion The very little sectional dimension more than thin portion;
The sectional dimension of transition part gradually decreasees from top to bottom or transition part is step variable-diameter structure.
In one embodiment of the present of invention, the edge of the lower end of expansion mouth is slided along the inner wall upper-lower seal of thin portion.
In one embodiment of the present of invention, the top of tube body is equipped with upper cover, is tightly connected between upper cover and tube body, upper cover Center is equipped with medium pore, and the cylindrical portion of compression bar passes through medium pore.
In one embodiment of the present of invention, upper lid is equipped with locking mechanism, for locking the position of compression bar.
In one embodiment of the present of invention, the outer rim of upper cover is equipped with balance hole;The lower surface of upper cover and the medial surface of tube body The space of formation is in communication with the outside by balance hole;Silica gel lid is equipped at balance hole.
In one embodiment of the present of invention, pushing structure is equipped with vertical intercommunicating pore, the hollow space of intercommunicating pore and compression bar Connection, intercommunicating pore are sealed by silica gel plug.
The advantageous effect of the embodiment of the present invention is:
1, technical solution of the present invention uses telescopic compression bar, and realizes Fu Xue little by the compression bar side port on compression bar The platelet poor plasma on plate blood plasma upper layer detaches, and can be according to the dosage of blood come the flexible of the adjustment compression bar of adaptability Amount, improves the adaptability of technical solution of the present invention, and the opening and closing of compression bar side port is realized by interior bar, can be by Platelet poor Blood plasma efficiently separates, and avoids more containers transfer of platelet rich plasma, and the blood platelet that more container transfer operations are brought is avoided to swash Living or pollution.
2, technical solution of the present invention keeps the tube body for containing blood opposing stationary motionless, avoids shaking blood when operation, Influence the quality of the platelet rich plasma prepared;By the movement of compression bar, separated plasma from top to bottom is contained using first chamber The platelet poor plasma separated is filled, then directly obtains the richness that platelet rich plasma can be obtained high concentration in hollow structure Thrombocyte plasma so that extraction operation is easier;
3, technical solution of the present invention various places inside is respectively provided with sealing structure, can effectively prevent outer bound pair platelet rich plasma Pollution.
It in the present invention, can also be combined with each other between above-mentioned each technical solution, to realize more preferred assembled schemes.This Other feature and advantage of invention will illustrate in the following description, also, certain advantages can become from specification it is aobvious and It is clear to, or understand through the implementation of the invention.The purpose of the present invention and other advantages can by specification, claims with And it realizes and obtains in specifically noted content in attached drawing.
Description of the drawings
Attached drawing is only used for showing the purpose of specific embodiment, and is not considered as limitation of the present invention, in entire attached drawing In, identical reference mark indicates identical component.
Fig. 1 is the overall structure diagram of the embodiment of the present invention;
Fig. 2 is the overall structure sectional view of the embodiment of the present invention;
Fig. 3-1 is the transition part schematic diagram of the step variable-diameter structure of the embodiment of the present invention;
Fig. 3-2 is the transition part schematic diagram of the arc of the embodiment of the present invention;
Fig. 4-1 is that the interior bar of the embodiment of the present invention rotates schematic diagram;
Fig. 4-2 is that the interior bar of the embodiment of the present invention moves up and down schematic diagram;
Reference numeral:10- tube bodies;101- first chambers;102- second chambers;11- thick portions;12- transition parts;13- thin portions; 20- upper covers;21- medium pores;30- compression bars;31- cylindrical portions;32- expansion mouths;33- compression bar side ports;34- interior bars;Bar side in 35- Mouthful;40- pushing structures;41- handles;42- silica gel plugs;43- intercommunicating pores.
Specific implementation mode
Specifically describing the preferred embodiment of the present invention below in conjunction with the accompanying drawings, wherein attached drawing constitutes the application part, and It is used to illustrate the principle of the present invention together with embodiments of the present invention, be not intended to limit the scope of the present invention.
An embodiment of the present invention provides a kind of platelet rich plasma preparation facilities, preparation facilities includes:Tube body 10, compression bar 30;10 top end opening bottom end closure of tube body;The lower edge of compression bar 30 is slided along the inner wall sealing of tube body 10;The inside of tube body 10 includes the One chamber 101 and second chamber 102, first chamber 101 are the chamber that 10 inner wall of tube body and compression bar outer wall are formed, second chamber 102 chambers formed with 30 inner wall of compression bar for the bottom surface of 10 inside of tube body;Compression bar 30 is hollow stem, and the side wall of compression bar 30 is equipped with Compression bar side port 33, compression bar side port 33 are connected to first chamber 101 and second chamber 102, and the number of compression bar side port 33 is unlimited, but equal position In on same level section.Compression bar 30 is in complete pull-up state when use, at this time the inner wall of the lower edge of compression bar 30 and tube body 10 Separation, first chamber 101 are connected to second chamber 102, and the space of 20 lower surface of upper cover and the formation of 10 medial surface of tube body contains blood Liquid after layering is centrifuged, pushes down on compression bar 30, and the inner wall contact and sealing of the lower edge and tube body 10 of compression bar 30 separate First chamber 101 and second chamber 102, at this time first chamber 101 be only connected to by compression bar side port 33 with second chamber 102, most The platelet poor plasma on upper layer will flow into first chamber 101 from compression bar side port 33, and top layer is rich blood in second chamber 102 Platelet-poor plasma can be taken out platelet rich plasma by the hollow structure of compression bar 30.In the embodiment of the present invention, pass through compression bar 30 It will detach, do not interfere with after whole separation positioned at the platelet poor plasma on platelet rich plasma upper layer to realize The middle part platelet rich plasma of blood avoids the transfer of more containers or vibrations of platelet rich plasma, ensure that rich platelet blood The high concentration of slurry.
The prior art can mainly be divided into three classes.
First kind prior art cardinal principle is:The structure for containing blood is kept fixed, the component by upper top is upward Blood is pushed, so that the platelet poor plasma on platelet rich plasma upper layer is overflowed, to obtain platelet rich plasma.But it this kind of sets Standby theres are a big disadvantage, can cause vibrations or shaking when the component on upper top moves upwards to blood, can make in blood other at Divide and be mixed into platelet rich plasma, influences the concentration of platelet rich plasma.Inventive embodiments then by way of from top to bottom come point Platelet poor plasma from platelet rich plasma upper layer, moving down for compression bar 30 do not interfere with other than platelet poor plasma Part ensure that the high concentration of platelet rich plasma.
Second class prior art cardinal principle is:It is centrifuged and is extracted twice twice, after centrifuging for the first time, from centrifugation The undermost red blood cell of blood afterwards is extracted out, and after second centrifuges, rich platelet is extracted out from the lowest level of the blood after centrifugation Blood plasma.But there are another two big disadvantages for this kind of equipment, need midway to open container, increase the possibility that blood plasma receives pollution, And remaining red blood cell can cause harmful effect to the stability and effect of platelet rich plasma when second of extraction.The present invention Embodiment in, direct first separation can directly extract platelet rich plasma, avoid frequent centrifugation and extract, reduce The contaminated possibility of platelet rich plasma, and the platelet rich plasma directly extracted, avoid red blood cell and are mixed into Fu Xue little Plate blood plasma ensure that the stability and validity of platelet rich plasma.
Third class prior art cardinal principle is:Blood after centrifugation is packed into intermediate thin thick container up and down, And it is deep into inside container using syringe directly extracts in a reservoir.But this kind of equipment was operated there is also two big disadvantages It needs syringe to go deep under liquid level extracting in journey, it is also necessary to which position and the posture for adjusting syringe can not only stir Fu Xue little Plate blood plasma makes the concentration of platelet rich plasma reduce, and also proposes higher requirement to the operation level of operating personnel, and operation is difficult It spends larger.The embodiment of the present invention is using the platelet poor plasma on the pushing separation upper layer of compression bar 30, and operating personnel are directly to the In two chambers 102 in remainder, the platelet rich plasma in upper layer extracted, avoid to platelet rich plasma Agitation, ensure that the concentration of platelet rich plasma, while also greatly simplifying operation difficulty.
Compression bar 30 is pushed down in order to more convenient, preparation facilities is additionally provided with pushing structure 40, and the setting of pushing structure 40 is being pressed The top of bar 30 thus can push down on compression bar 30 by pushing meanss, realize the pushing of compression bar 30, make second chamber The platelet poor plasma of top layer is spilt into from compression bar side port 33 in first chamber 101 in 102.Illustratively, pushing structure 40 The handle 41 of T shapes is could be provided as, lower end is connect with compression bar 30.
The embodiment of the present invention when in use, needs blood being contained in tube body 10, and whole equipment carries out together with blood It centrifuges, is shifted to avoid more containers of blood.In order to avoid platelet rich plasma is also spilt into first chamber 101, need Want compression bar side port 33 that can be turned on and off.For this purpose, in the embodiment of the present application, the inside of compression bar 30 is additionally provided with interior bar 34, interior bar 34 is hollow stem, and is connect with pushing structure 40;Interior bar 34 is sleeved on inside compression bar 30, not there are gap, and interior bar 34 Sealing state rotation is kept when carrying out axial direction and/or circumferential movement along the inner surface of compression bar 30, and moving;On the side wall of interior bar 34 Equipped with interior bar side port 35, and interior bar side port 35 is corresponding with the position of compression bar side port 33.Interior bar side port 35 can ensure in interior bar When side port 35 is aligned with compression bar side port 33, compression bar side port 33 is opened, and first chamber 101 is connected to second chamber 102, Platelet poor Blood plasma can be spilt by interior bar side port 35 and compression bar side port 33 in first chamber 101, realize separation.Interior bar 34 is tied with promotion Structure 40 connects, and pushing structure 40 can individually control the rotation of interior bar 34 or upward-downward translation or a combination of both so that interior bar side port 35 It misplaces with compression bar side port 33, realizes the closing of compression bar side port 33, first chamber 101 is not connected to second chamber 102, and anaemia is small After plate blood plasma is totally separated, platelet rich plasma also will not first be spilt into from compression bar side port 33 in first chamber 101.Although interior bar 34 are sleeved in compression bar 30, and do not have gap, but blood can still be oozed out by connecting portion, be sealed between interior bar 34 and compression bar 30 Anti- Hemostatic Oral Liquid is contributed to be oozed out between interior bar 34 and compression bar 30.
Illustratively, interior bar 34 rotates in compression bar 30, and in the present embodiment, compression bar 30 is internally provided with annular groove, interior bar 34 are equipped with annular protrusion, and the annular protrusion of interior bar 34 is caught in annular groove so that interior bar 34 is circumferentially rotated along annular groove so that pressure Bar side mouth 33 misplaces with interior bar side port 35, realizes the closing of compression bar side port 33.
Illustratively, the translation in the compression bar 30 of interior bar 34, in the present embodiment, compression bar 30 is internally provided with parallel struts 30 The cannelure of axis, interior bar 34 is equipped with the longitudinally convex of the axis of parallel interior bar 34, longitudinally convex to be caught in cannelure so that interior The slot upper and lower translation along longitudinal direction of bar 34 so that compression bar side port 33 misplaces with interior bar side port 35, realizes the closing of compression bar side port 33.
For more accurate clearly capable of judging the considerations of whether platelet poor plasma is totally separated out, present invention reality It applies in example, compression bar 30 includes cylindrical portion 31 and expansion mouth 32;Cylindrical portion 31 and expansion mouth 32 are from top to bottom arranged;Interior bar 34 is sleeved on Cylindrical portion 31;The sectional dimension of expansion mouth 32 from top to bottom gradually increases.Blood in second chamber 102 is pushed in compression bar 30 When, expansion mouth 32 is first passed through, is overflowed by cylindrical portion 31, and by compression bar side port 33, due to the sectional dimension of expansion mouth 32 It is up-small and down-big, when compression bar 30 push very little apart from when, the height that liquid level rises in cylindrical portion 31 also can be bigger, for rich blood Platelet-poor plasma preparation facilities no matter the prior art or the embodiment of the present invention, be generally used transparent material, so, Ke Yigeng Add whether intuitive observation platelet poor plasma all spills into first chamber 101.
Platelet poor plasma, middle tube body of the embodiment of the present invention 10 are contained in order to allow first chamber 101 to have sufficient space Include from top to bottom:Thick portion 11, transition part 12 and thin portion 13, the sectional dimension of thick portion 11 are more than the sectional dimension of thin portion 13;It crosses The sectional dimension for crossing portion 12 gradually decreasees from top to bottom, or, transition part 12 is step variable-diameter structure.The setting of thick portion 11 ensure that First chamber 101 has larger space, and in 30 pull-up of compression bar in the lower edge of expansion mouth 32 and the thin portion 13 of tube body 10 Wall separates;Transition part 12 is for connecting thick portion 11 and thin portion 13, and illustratively, transition part 12 can be sectional dimension even variation Taper surface or step variable-diameter structure or arcwall face.
In the embodiment of the present invention, the lower edge of the expansion mouth 32 of compression bar 30 is slided up and down along the inner wall of the thin portion 13 of tube body 10, And it is sealed between the inner wall of the thin portion 13 of the lower edge and tube body 10 of the expansion mouth 32 of compression bar 30.At this point, first chamber 101 is thick portion On the outside of 13 inside of thin portion, expansion mouth 32 on the inside of 11 insides, transition part 12, more than 32 lower edge of expansion mouth and 31 outside of cylindrical portion Between chamber, second chamber 102 is the inside of expansion mouth 32, the inside of interior bar 34, the bottom surface of the inside of tube body 10 and expansion mouth 32 The chamber that lower edge 13 inside of thin portion below surrounds.It crosses between 10 thin portion 13 of oral area lower edge and tube body and seals, can effectively prevent When expansion mouth 32 slides, blood penetrates into first chamber 101 between expansion mouth 32 and thin portion 13.
In the embodiment of the present invention, the top of tube body 10 is equipped with upper cover 20, is tightly connected between upper cover 20 and tube body 10, upper cover 20 center is equipped with medium pore 21, and the cylindrical portion 31 of compression bar 30 passes through medium pore 21.Upper cover 20 is used for carrying out whole equipment close Medium pore 21 is arranged in envelope, upper cover 20, and compression bar 30 passes through medium pore 21, moves up and down.
When in use due to the embodiment of the present invention, need blood being contained in tube body 10, whole equipment with blood together Centrifugally operated is carried out, compression bar 30 and the needs of tube body 10 keep opposing stationary when being centrifuged, so upper cover 20 is equipped with locking Structure, for locking the position of compression bar 30.Illustratively, locking mechanism may be used thread forms and be locked, and in compression bar 30 outsides are threaded, and nut is arranged in upper cover 20, realize that on-fixed connects by spacing ring between nut and upper cover 20, Nut and the screw thread in 30 outside of compression bar screw, you can realize locking;Locking mechanism can also use snap ring form, on compression bar 30 Equipped with annular groove, spacing ring is set, spacing ring is caught in annular groove in upper cover 20, you can realize locking.
In view of being sealed between upper cover 20 and tube body 10, when injecting blood in tube body 10, air pressure inside can make blood It is difficult to inject in tube body 10.Therefore, the outer rim of upper cover 20 is equipped with balance hole in the embodiment of the present invention;The lower surface of upper cover 20 and pipe The space that the medial surface of body 10 is formed is in communication with the outside by balance hole;Silica gel lid is equipped at balance hole.Connected by balance hole Siphunculus body 10 it is inside and outside, can realize smooth injection of the blood into tube body 10, while the silica gel lid sealed can prevent other steps Pollutant enters inside device in rapid.
The embodiment of the present invention when in use, platelet rich plasma, pushing structure is obtained by the hollow structure of compression bar 30 40 are equipped with vertical intercommunicating pore 43, and intercommunicating pore 43 is connected to the hollow space of compression bar 30, are used for through syringe, intercommunicating pore 43 is logical The sealing of silica gel plug 42 is crossed, contaminants blood plasma can be both prevented, can also prevent the device of the embodiment of the present invention from containing blood Blood spluttering when centrifuging together.
In view of the device of the embodiment of the present invention in some cases will not be made using transparent material, then can not be by straight The form for connecing the observation page judges whether the platelet poor plasma of top layer is totally separated out, the embodiment of the present invention In, the lateral wall of compression bar 30 is equipped with scale, and the distance pushed by compression bar 30 judges that how many blood plasma passes through compression bar side port 33 are flowed into first chamber 101, since various composition is relatively fixed in blood, in the case of known total blood volume, very It is easy to get the volume of platelet poor plasma, also can judge platelet poor plasma whether by the scale on compression bar 30 Through being totally separated out.
The application method of the embodiment of the present invention is:
Interior bar 34 is rotated, so that interior bar side port 35 and compression bar side port 33 is misplaced, at the connecting hole 43 for opening pushing structure 40 The silica gel lid of the balance hole of 20 outer rim of silica gel plug 42 and upper cover, pulling up compression bar 30 makes the lower edge and tube body 10 of expansion mouth 32 Thin portion 13 separates, and the blood of extraction is injected into tube body 10 by the intercommunicating pore 43 of pushing structure 40 and the hollow space of compression bar 30 It is interior;
Compression bar 30 and the relative position of upper cover 20 are fixed by locking mechanism, covered at the intercommunicating pore 43 of pushing structure 40 Silica gel plug 42, be centrifuged, the blood in tube body 10 made to be divided into platelet poor plasma, tunica albuginea layer and red blood cell layer;
Fixation of the locking mechanism to compression bar 30 and upper cover 20 is released, interior bar 34 is rotated, makes interior bar side port 35 and compression bar side port 33 alignment;
By pushing structure 40, compression bar 30 is slowly pushed down on, keeps 32 lower edge of expansion mouth of compression bar 30 and tube body 10 thin Space in tube body 10 is divided into first chamber 101 and second chamber 102 by portion's 13 inner wall contact, compression bar 30;
Continuation slowly pushes down on compression bar 30, and the blood of layering is gradually increasing along the hollow structure of compression bar 30, Platelet poor Blood plasma flows into first chamber 101 by interior bar side port 35 and compression bar side port 33;
It directly observes liquid level or observes the scale on compression bar 30, when platelet poor plasma fully enters first chamber 101, Stop pushing compression bar 30, rotate interior bar 34, so that interior bar side port 35 and compression bar side port 33 is misplaced, open the intercommunicating pore of pushing structure 40 Silica gel plug 42 at 43;
The female Luer of syringe is connect with the intercommunicating pore 43 of pushing structure 40, compression bar 30 is continued to press on, by Fu Xue little Plate blood plasma is pressed into syringe, stops pushing compression bar 30 when red blood cell occurs in syringe port, is removed syringe, is in syringe For the platelet rich plasma of high concentration.
In conclusion an embodiment of the present invention provides a kind of platelet rich plasma preparation facilities, telescopic pressure is used Bar, and realize that the platelet poor plasma on platelet rich plasma upper layer detaches by the compression bar side port on compression bar, and can root The stroke for carrying out the adjustment compression bar of adaptability according to the dosage of blood, improves the adaptability of technical solution of the present invention, and by interior Bar realizes the opening and closing of compression bar side port, can efficiently separate platelet poor plasma, avoids more containers of platelet rich plasma Transfer, the platelet activation for avoiding more container transfer operations from bringing or pollution;Keep the tube body for containing blood opposing stationary motionless, It avoids shaking blood when operation, influences the quality of the platelet rich plasma prepared;By the movement of compression bar, point from top to bottom From blood plasma, the platelet poor plasma separated is contained using first chamber, then directly obtains Fu Xue little in hollow structure Plate blood plasma can be obtained the platelet rich plasma of high concentration so that extraction operation is easier;It is each inside technical solution of the present invention Place is respectively provided with sealing structure, can effectively prevent the pollution of outer bound pair platelet rich plasma.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Any one skilled in the art in the technical scope disclosed by the present invention, the change or replacement that can be readily occurred in, It should be covered by the protection scope of the present invention.

Claims (10)

1. a kind of platelet rich plasma preparation facilities, which is characterized in that the preparation facilities includes:Tube body (10), compression bar (30); Tube body (10) the top end opening bottom end closure, the tube body (10) include first chamber (101) and second chamber (102);Institute The inner wall sealing sliding of the lower end edge tube body (10) of compression bar (30) is stated, the compression bar (30) is hollow stem, the compression bar (30) Side wall is equipped with compression bar side port (33), and the compression bar side port (33) is connected to the first chamber (101) and second chamber (102).
2. preparation facilities according to claim 1, which is characterized in that the preparation facilities is additionally provided with pushing structure (40), Top of pushing structure (40) setting in the compression bar (30).
3. preparation facilities according to claim 2, which is characterized in that the compression bar (30) further includes interior bar (34), described Interior bar (34) is hollow stem, and is connect with the pushing structure (40);The interior bar (34) is set in the compression bar (30), and The interior bar (34) carries out axial direction and/or circumferential movement along the inner surface of the compression bar (30), and when movement keeps sealing state;Institute The side wall for stating compression bar (30) is equipped with interior bar side port (35), and interior bar side port (35) is corresponding with the position of compression bar side port (33).
4. preparation facilities according to claim 3, which is characterized in that the compression bar (30) includes the cylinder being from top to bottom arranged Shape portion (31) and expansion mouth (32), the interior bar (34) are set in the cylindrical portion (31);The section of the expansion mouth (32) Size from top to bottom gradually increases.
5. preparation facilities according to claim 4, which is characterized in that the tube body (10) includes from top to bottom:Thick portion (11), transition part (12) and thin portion (13), the sectional dimension of the thick portion (11) are more than the sectional dimension of the thin portion (13);
The sectional dimension of the transition part (12) gradually decreasees from top to bottom or the transition part (12) is step variable-diameter structure.
6. preparation facilities according to claim 5, which is characterized in that the edge of the lower end of the expansion mouth (32) is described in The inner wall upper-lower seal of thin portion (13) is slided.
7. preparation facilities according to claim 4, which is characterized in that the top of the tube body (10) is equipped with upper cover (20), It is tightly connected between the upper cover (20) and the tube body (10), the center of the upper cover (20) is equipped with medium pore (21), described The cylindrical portion (31) of compression bar (30) passes through the medium pore (21).
8. preparation facilities according to claim 7, which is characterized in that the upper cover (20) is equipped with locking mechanism, is used for Lock the position of the compression bar (30).
9. preparation facilities according to claim 8, which is characterized in that the outer rim of the upper cover (20) is equipped with balance hole;Institute The space that the medial surface of the lower surface, tube body (10) of stating upper cover (20) is formed is in communication with the outside by the balance hole;It is described flat Heng Kongchu is equipped with silica gel lid.
10. according to any preparation facilities of claim 2 to 9, which is characterized in that the pushing structure (40) is equipped with vertical Intercommunicating pore (43), the intercommunicating pore (43) is connected to the hollow space of the compression bar (30), and the intercommunicating pore (43) passes through silicon Rubber plug (42) seals.
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CN110201424A (en) * 2019-04-22 2019-09-06 福州比华利美容医院有限公司 Combined type blood constituent separator
CN111974475A (en) * 2020-08-20 2020-11-24 绵阳晶凯圣生物科技有限公司 Blood component separator
CN112371198A (en) * 2020-11-24 2021-02-19 康膝生物医疗(深圳)有限公司 Device and method for preparing injection type autologous i-PRF
CN113456910A (en) * 2021-08-12 2021-10-01 起源细胞技术(滁州)有限公司 Platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation
CN114870436A (en) * 2022-06-21 2022-08-09 浙江保尔曼生物科技有限公司 Platelet-rich plasma preparation device and preparation method thereof
CN115770414A (en) * 2023-01-30 2023-03-10 冠昊生物科技股份有限公司 Centrifuge tube for preparing platelet-rich plasma and centrifugation method thereof

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