CN108653505A - Grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice - Google Patents
Grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice Download PDFInfo
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- CN108653505A CN108653505A CN201810733286.2A CN201810733286A CN108653505A CN 108653505 A CN108653505 A CN 108653505A CN 201810733286 A CN201810733286 A CN 201810733286A CN 108653505 A CN108653505 A CN 108653505A
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- CN
- China
- Prior art keywords
- grass
- materical crude
- medicine materical
- fresh
- leaved sweetflag
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of " grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that:Grass-leaved sweetflag harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of grass-leaved sweetflag medicine materical crude slice.
Background technology
Chinese medicine grass-leaved sweetflag is acorus gramineus araceae plantAcorus tatarinowii The dry rhizome of Schott, tool
There is the effect of slit phlegm of having one's ideas straightened out, inducing resuscitation intelligence development, dampness elimination appetizing.It can be used for coma epilepsy, forgetful insomnia, Hiccough and deaf, gastral cavity ruffian is not hungry,
The treatment of apnea etc. is a herb common on tcm clinical practice.The processing method of traditional grass-leaved sweetflag is:Medicinal material is excavated
Afterwards, fibrous root and silt are removed, is dried, is packaged, storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Thus
The grass-leaved sweetflag medicine materical crude slice volume arrived is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested, being unfavorable for taking care of, store and transport into
This height.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore,
Develop a kind of stable quality is reliable, storage/transportation is at low cost, conducive to keeping, carry and easy to use, rapid-action novel stone Chang
Pu medicine materical crude slice, it is imperative.Existing market grass-leaved sweetflag medicine materical crude slice, other than traditional medicine materical crude slice, also Ultramicro-powder medicine materical crude slice and concentrated granular
Two kinds of forms of medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece
It cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only extract water-soluble components.
Invention content
The invention discloses a kind of " grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that:In grass-leaved sweetflag
After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~
The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering,
Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.02 ~ 1.10 concentrate.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.By the spray powder of collection with it is spare
Concentrate mixing granulation, dry to be less than 10% to water content, whole grain is vacuum-packed to get finished product.Grass-leaved sweetflag granule pieces quality
Stablize, good fluidity, clinical general usage amount is 1 ~ 5g.Such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter capsule
In agent and tablet, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.
The present invention solve traditional grass-leaved sweetflag medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested,
The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular
Medicine materical crude slice is more preferable.
Specific embodiment
It after grass-leaved sweetflag medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction
Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.
The concentrate of gained is left and taken into 3% spare, remaining spray drying.Spray powder is collected, pelleting is mixed with spare concentrate,
It is 10% that 80 DEG C, which are dried under vacuum to water content, and whole grain is vacuum-packed to get finished product.
Claims (2)
1. a kind of grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that:After grass-leaved sweetflag harvesting, clean in time,
Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~
The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 are added in the gained dregs of a decoction
The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, cross 60 ~
100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density;Gained concentrate leaves and takes 1% ~ 3%
It is spare, remaining spray drying;By the spray powder of collection and spare concentrate mixing granulation, drying to water content is whole less than 10%
Grain is vacuum-packed to get finished product.
2. grass-leaved sweetflag according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that:Clinic generally makes
Dosage is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733286.2A CN108653505A (en) | 2018-07-06 | 2018-07-06 | Grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733286.2A CN108653505A (en) | 2018-07-06 | 2018-07-06 | Grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108653505A true CN108653505A (en) | 2018-10-16 |
Family
ID=63773536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810733286.2A Withdrawn CN108653505A (en) | 2018-07-06 | 2018-07-06 | Grass-leaved sweetflag is fresh to carry spray-dried granules medicine materical crude slice |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108653505A (en) |
-
2018
- 2018-07-06 CN CN201810733286.2A patent/CN108653505A/en not_active Withdrawn
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181016 |