CN108578558A

CN108578558A - Rhizoma anemarrhenae is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108578558A
Application number: CN201810733372.3A
Authority: CN
Inventors: 徐漫
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-09-28

Abstract

The invention discloses a kind of " rhizoma anemarrhenae is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Rhizoma anemarrhenae harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.

Description

Rhizoma anemarrhenae is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of rhizoma anemarrhenae medicine materical crude slice.

Background technology

Anemarrhena asphodeloides Bge is the dry rhizome of liliaceous plant rhizoma anemarrhenae, has the effect of clearing heat-fire, nourishing Yin and moistening dryness.It is usually used in Fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia, lung-heat type cough, osteopyrexia and fever, Heat Diabetes, the treatment of dry constipation of intestines etc. are normal on tcm clinical practice The a herb seen.The processing method of traditional rhizoma anemarrhenae is：After medicinal material is excavated, fibrous root and silt are removed, dries, hits unhairing, beat Packet, storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Thus obtained rhizoma anemarrhenae medicine materical crude slice volume is big, hygiene Standard deviation is easy to make moist, is mildew, infested, being unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality is stablized Property it is poor, clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore, develop that a kind of stable quality is reliable, storage/fortune It is defeated it is at low cost, conducive to keeping, carry and easy to use, rapid-action novel rhizoma anemarrhenae medicine materical crude slice, it is imperative.Existing market rhizoma anemarrhenae is drunk Piece, other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both with traditional medicine materical crude slice For raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular is only Water soluble ingredient can be extracted.

Invention content

The invention discloses a kind of " rhizoma anemarrhenae is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：It is harvested in rhizoma anemarrhenae Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.02 ~ 1.10 concentrate.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.By the spray powder of collection with it is spare Concentrate mixing granulation, dry to be less than 10% to water content, whole grain is vacuum-packed to get finished product.Finished product medicine materical crude slice rhizoma anemarrhenae saponin BII (C₄₅H₇₆O₁₉) content must not be less than 4.0%.Rhizoma anemarrhenae granule pieces stable quality, good fluidity, clinical general usage amount is 1 ~ 5g.Such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet, make to substantially increase clinic Convenience and compliance are conducive to the treatment of clinical acute disease.

The present invention solve traditional rhizoma anemarrhenae medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after rhizoma ane marrhenae is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.It will The concentrate of gained leaves and takes 3% spare, remaining spray drying.Spray powder is collected, mixes pelleting with spare concentrate, 80 It is 10% DEG C to be dried under vacuum to water content, and whole grain is vacuum-packed to get finished product.Finished product medicine materical crude slice rhizoma anemarrhenae saponin BII (C₄₅H₇₆O₁₉) contain Amount is 4.5%.

Claims

1. a kind of rhizoma anemarrhenae is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：It after rhizoma anemarrhenae harvesting, cleans, removes in time The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 ~ 10 are added in the gained dregs of a decoction The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, crosses 60 ~ 100 Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；It is standby that gained concentrate leaves and takes 1% ~ 3% With remaining spray drying；By the spray powder of collection and spare concentrate mixing granulation, drying to water content is whole less than 10% Grain is vacuum-packed to get finished product；Finished product medicine materical crude slice rhizoma anemarrhenae saponin BII (C₄₅H₇₆O₁₉) content must not be less than 4.0%.

2. rhizoma anemarrhenae according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.