CN108653475A - A kind of Chinese medicine and preparation method thereof of prevention senile dementia - Google Patents
A kind of Chinese medicine and preparation method thereof of prevention senile dementia Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicines of prevention senile dementia, include the bulk pharmaceutical chemicals of following parts by weight：100 parts of Radix Polygoni Multiflori, 80 100 parts of the white fleece-flower root, 40 50 parts of the root of bidentate achyranthes, 40 50 parts of fushen, 80 100 parts of poria cocos, 80 100 parts of PORIA ALBA, 40 50 parts of the fruit of Chinese wolfberry, 40 50 parts of Semen Cuscutae, 40 50 parts of Radix Angelicae Sinensis, 24 30 parts of fructus psoaleae, 24 30 parts of Cortex Eucommiae, 10 20 parts of English walnut, 10 20 parts of fructus sophorae.This composition has treatment weakness, deficiency of kidney-QI, help yang-energy, improving eyesight dark hair can play the role of calm, intelligence development invigorating the spleen, have fine curative effect for neurasthenia, senile dementia, there is good therapeutic effect for the illnesss such as insomnia, forgetful, ball is made, instant edible is hollow to be taken with wine or light salt brine, heat wine plays the role of promoting blood circulation and removing blood stasis on a small quantity, is conducive to drug absorption.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine and preparation method thereof of prevention senile dementia.
Background technology
Alzheimer disease (AD) is a kind of nervous system degenerative disease of the progress sexual development of onset concealment.Clinically
With memory disorders, aphasia, appraxia, agnosia, the damage of visual space technical ability, execute dysfunction and personality and behavior change etc. comprehensively
Property dementia performance be characterized, the cause of disease is unknown so far.The disease onset slowly or concealment, patient and household be often unable to explain clearly when onset.
Be more common in 70 years old or more (average 73 years old of male, women are 75 years old) old man, a few patients physical disease, fracture or spirit by
Symptom is clear rapidly after stimulation.Women is more compared with male (female: man is 3: 1).It is mainly shown as decrease of cognitive function, mental symptom
It is gradually reduced with behavior disorder, activity of daily living.When being divided into three according to the deterioration degree of cognitive ability and physical function
Phase：First stage (1~3 year) is the mild dementia phase.Hypomnesia is shown as, ecmnesia is protruded；Judgement declines,
Patient cannot analyze event, thinks deeply, judge, it is difficult to handle complicated problem；Work or housework are careless, no
It can independently be done shopping, economic affairs etc., it is social difficult；Although remaining to do a little known routine works, to new things
But it shows ignorantly to be difficult to resolve, apathy, excitation, often has suspicious once in a while；Time of occurrence disorientation, to residing place and people
Object can make orientation, and difficult, the visual space energy force difference of labyrinth is oriented to residing geographical location；Speech vocabulary is few, and name is tired
It is difficult.Second stage (2~10 years) is the moderate dementia phase.It shows as far and near memory to be badly damaged, the visual space ability of simple structure
Decline, time, disturbance of orientation to place；Process problem, distinguish things similitude and discrepancy in terms of have serious damage；It cannot
It is independent to carry out outdoor activity, wearing the clothes, personal hygiene and want help in terms of keeping personal appearance；Calculating cannot；Occur each
Kind nervous symptoms, it is seen that aphasia, appraxia and agnosia；Emotion becomes irritable uneasy from indifferent, often walks about and does not stop, it is seen that the urinary incontinence.
Phase III (8~12 years) is severe dementia phase.Patient has been completely dependent on caregiver, and segment is only deposited in serious memory loss
Memory；Daily life cannot take care of oneself, gatism, and presentation keeps silent, rigid limbs, and the visible pyramidal sign of physical examination is positive, has
The primary reflections such as hold, grope and suck by force.Final stupor, generally dies of the complication such as infection.
Senile dementia, mainly since kidney essense declines withered, marrow subtracts brain and disappears, caused by refreshing machine appraxia, this disease in brain, but with kidney,
The Zang-Fu relationships such as the heart, liver, spleen are close, belong to all dirty losss, caused by insufficiency of vital energy and blood.
Invention content
To overcome the deficiency, the purpose of the present invention is to provide a kind of Chinese medicine of prevention senile dementia and its preparation sides
Method.
The technical solution adopted by the present invention to solve the technical problems is：A kind of Chinese medicine of prevention senile dementia, including with
The bulk pharmaceutical chemicals of lower parts by weight：100 parts of Radix Polygoni Multiflori, white fleece-flower root 80-100 parts, 40-50 parts of the root of bidentate achyranthes, 40-50 parts of fushen, red Fu
80-100 parts of Siberian cocklebur, 80-100 parts of PORIA ALBA, 40-50 parts of the fruit of Chinese wolfberry, 40-50 parts of Semen Cuscutae, 40-50 parts of Radix Angelicae Sinensis, fructus psoaleae 24-30
Part, 24-30 parts of Cortex Eucommiae, 10-20 parts of English walnut, 10-20 parts of fructus sophorae.
Specifically, further include 20-25 parts of dogwood fruit, 10-15 parts of pilose antler, pilose antler needs unhairing shortcake to process.
A kind of Chinese medicinal preparation method of prevention senile dementia, includes the following steps：
(1) 80-100 parts of Radix Polygoni Multifloris, the white fleece-flower root are weighed respectively, are impregnated in water in which rice has been washed, peeling is scraped with bamboo knife, be sliced,
Wherein water in which rice has been washed is third time or the 4th limpid water in which rice has been washed after rice washing；
(2) the 40-50 roots of bidentate achyranthes are weighed, Radix Polygoni Multiflori, the white fleece-flower root and black soya bean place mat after being impregnated with step (1) is middle,
In be followed successively by one layer of root of bidentate achyranthes, one layer of black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean from top to bottom,
Steam 15min in marmite, after cooling completely, remove out black soya bean, laying steams 15min, wherein be followed successively by from top to bottom one layer of root of bidentate achyranthes,
One layer of black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean steam three times again repeatedly, go except black altogether
Beans leave and take Radix Polygoni Multiflori, the white fleece-flower root and the root of bidentate achyranthes；
(3) 40-50 parts of fushen is weighed, takes cow's milk or sheep breast to mix for use；
(4) 80-100 parts of poria cocos is weighed, cow's milk is taken to soak one night, weighs 80-100 parts of PORIA ALBA, sheep breast leaching one night dries；
(5) 40-50 parts of the fruit of Chinese wolfberry is weighed, steeping in wine, which is washed, to be dried；
(6) 40-50 parts of Semen Cuscutae is weighed, after steeping in wine, boiling 15min is dried
(7) 40-50 parts of Radix Angelicae Sinensis is weighed, steeping in wine one night dries；
(8) 24-30 parts of fructus psoaleae, stir-bake to yellowish are weighed；
(9) 10-20 parts of English walnut is weighed, is smashed to pieces such as mud；
(10) 24-30 parts of Cortex Eucommiae is weighed, cow's milk soaks one night, dries, silk is removed in quick-fried；
(11) 10-20 parts of fructus sophorae, stir-bake to yellowish color are weighed；
By the Radix Polygoni Multiflori left and taken in step (2), the white fleece-flower root, the root of bidentate achyranthes and step (3) to (11) treated former material
Material is put into the mill of non-ironware and is ground into smalls, adds honey to be smelt ball, ball size is 0.1-0.2 grams, each taking 70-90
Ball, three times per day, hollow heat wine or light salt brine take.
Specifically, when honey is smelt ball, 20-25 parts of dogwood fruits, 10-15 parts of Pilose Antlers are added.
Specifically, during step (1) to the raw material disposal of step (11), ironware cannot be stained with.
The pharmacology of main important source material used in the present invention is as follows：
The fleece-flower root：Climing purple, spend it is yellowish-white, Ye Rushu it is pre- and not only, life must be opposite, and root has red, white two kinds as large as fist, red
Hero, white person are female.Fleece-flower root survivor's bitter and puckery flavor then has sugariness, slightly warm in nature concurrently after system is ripe.Major function is blood-nourishing strengthening the essence, flat tonifying liver
Kidney, black beard and hair.And just laxation, the scrofula that disappears, preventing and curing malaria disease can be moistened.This product is warm but not dry, mends and oiliness, and property is gentle, is suitable for long term usage,
Old age, prolonged illness, postpartum lose blood, and due to Tianjin blood deficiency, the enteron aisle body fluid that arrives lacks, and intestinal tube conduction is not smooth, and constipation is obstructed
Person, recent studies this product have cardiac effect, and particularly with the heart of fatigue, effect becomes apparent, and can prevent cholesterol
In intrahepatic deposition, mitigate atherosclerosis, institute has obvious curative effects for prevention senile dementia；
The root of bidentate achyranthes：Bitter, acid, mild-natured, main function is：Filling liver kidney, strengthening the bones and muscles, scattered silt blood, priming downlink.
Fushen：It is sweet in flavor, mild-natured, there are mental-tranquilization, the relieving convulsion effect throbbed with fear surely kind to control uneasy heartbeat, insomnia and insobriety
Chu, the diseases such as be easy to forget things, and has releasing to have no peace of mind, the dry tired effect of anger.
PORIA ALBA：Common Poria cocos refers generally to PORIA ALBA, and slightly sweet flavor is mild-natured, main function taste：Li Shui dehumidifying, calming heart peace
God, beneficial spleen stopping leak have the property of help concurrently, and evil righting can be used.
Poria cocos：The light red person of color, referred to as poria cocos in Poria cocos, relatively clearing heat and promoting diuresis.
The fruit of Chinese wolfberry：It is sweet in flavor mild-natured, there is nourishing liver and kidney, benefiting shrewd head.
Semen Cuscutae：Acrid-sweet flavor, it is warm-natured, it is mainly used for tonifying liver renal drug, for the lumbocrural pain caused by kidney deficiency and liver, impotence
Seminal emission, hypopsia, the diseases such as dribbling urination are all often used.
Radix Angelicae Sinensis：Acrid-sweet flavor, slight bitter, warm-natured, main work(is invigorated blood circulation, for enriching blood because the heart and blood have close relationship, so claiming
For green blood bushing, the illness for treating the loss of the deficiency of blood such as pale complexion, dizzy, heartbeat, dredging collateral, eliminating stasis to subdue swelling, ease constipation
Menstruation is adjusted in defaecation.Wine is washed or prepared RADIX ANGELICAE SINENSIS with yellow rice wine parched with wine, relatively activating blood circulation.
Fructus psoaleae：Acrid flavour is bitter, the big temperature of property, and main function is kidney-replenishing, and Gu Xiayuan, warming spleen and stomach, solid intestines, stopping leak rush down.
English walnut：Hardship lets out the scattered stasis of blood, there is the effect of stronger promoting blood circulation for regulating menstruation, removing blood stasis for promoting tissue regeneration, also has ease constipation, cough-relieving effect concurrently.
Cortex Eucommiae：Sweet in flavor, micro-pungent, it is warm-natured, common filling liver kidney, strengthening the bones and muscles, beneficial waist and knee drug, recent studies shows Du
It is secondary to play the role of blood pressure lowering.
Fructus sophorae：Bitter, it is cold in nature, there are heat-clearing, cool blood, eliminating dampness.
Dogwood fruit：It is sour and bitter, slightly warm in nature, function filling liver kidney, salubrity body.
Pilose antler：It is sweet in flavor, it is warm-natured, be mainly used for invigorating kidney yang, benefiting essence-blood, tonifying Qi effect.
The invention has the advantages that：This composition, which has, treats weak, deficiency of kidney-QI, help yang-energy, and improving eyesight is black
Hair, can play the role of calm, intelligence development invigorating the spleen, have fine curative effect for neurasthenia, senile dementia, for having a sleepless night, being good for
The illnesss such as forgetting has good therapeutic effect, ball is made, instant edible is hollow to be taken with wine or light salt brine, and a small amount of heat wine has
Effect promoting blood circulation and removing blood stasis, is conducive to drug absorption.
Specific implementation mode
It is further illustrated the present invention below by embodiment.It should be understood that the embodiment of the present invention is for illustrating
Rather than limiting the invention, the simple modifications that essence according to the present invention carries out the present invention belong to the present invention to the present invention
Claimed range.
One, embodiment
Embodiment 1
A kind of Chinese medicine of prevention senile dementia, includes the bulk pharmaceutical chemicals of following parts by weight：Radix Polygoni Multiflori 500g, the white fleece-flower root
500g, root of bidentate achyranthes 250g, fushen 250g, poria cocos 500g, 500 parts, fruit of Chinese wolfberry 500g, Semen Cuscutae 500g, Radix Angelicae Sinensis 500g of PORIA ALBA,
Fructus psoaleae 160g, Cortex Eucommiae 160g, English walnut 80g, fructus sophorae 80g.
Specifically, further include dogwood fruit 110g, pilose antler 80g, pilose antler needs unhairing shortcake to process.
Above-mentioned raw materials follow the steps below processing：
(1) Radix Polygoni Multiflori, the white fleece-flower root are weighed respectively, are impregnated in water in which rice has been washed, peeling is scraped with bamboo knife, be sliced, wherein rice swill
Water is third time or the 4th limpid water in which rice has been washed after rice washing；
(2) root of bidentate achyranthes is weighed, Radix Polygoni Multiflori, the white fleece-flower root and black soya bean place mat after being impregnated with step (1) is middle, wherein certainly
Top to bottm is followed successively by one layer of root of bidentate achyranthes, one layer of black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean, in sand
Steam saturating 15min in pot, after cooling completely, remove out black soya bean, laying steams 15min, wherein be followed successively by from top to bottom one layer of root of bidentate achyranthes, one layer
Black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean steam three times again repeatedly, remove black soya bean, stay altogether
Take Radix Polygoni Multiflori, the white fleece-flower root and the root of bidentate achyranthes；
(3) fushen is weighed, takes cow's milk or sheep breast to mix for use；
(4) poria cocos is weighed, cow's milk is taken to soak one night, weighs PORIA ALBA, sheep breast leaching one night dries；
(5) fruit of Chinese wolfberry is weighed, steeping in wine, which is washed, to be dried；
(6) Semen Cuscutae is weighed, after steeping in wine, boiling 15min is dried
(7) Radix Angelicae Sinensis is weighed, steeping in wine one night dries；
(8) fructus psoaleae, stir-bake to yellowish are weighed；
(9) English walnut is weighed, is smashed to pieces such as mud；
(10) Cortex Eucommiae is weighed, cow's milk soaks one night, dries, silk is removed in quick-fried；
(11) fructus sophorae, stir-bake to yellowish color are weighed；
By the Radix Polygoni Multiflori left and taken in step (2), the white fleece-flower root, the root of bidentate achyranthes and step (3) to (11) treated former material
Material is put into the mill of non-ironware and is ground into smalls, adds honey to be smelt ball, ball size is 0.1-0.2 grams, each taking 70-90
Ball, three times per day, hollow heat wine or light salt brine take.
Specifically, when honey is smelt ball, addition dogwood fruit, Pilose Antler, obtain sample 1.
Specifically, during step (1) to the raw material disposal of step (11), ironware cannot be stained with.
Embodiment 2
A kind of Chinese medicine of prevention senile dementia, includes the bulk pharmaceutical chemicals of following parts by weight：Radix Polygoni Multiflori 500g, the white fleece-flower root
500g, root of bidentate achyranthes 200g, fushen 250g, poria cocos 400g, PORIA ALBA 400g, fruit of Chinese wolfberry 400g, Semen Cuscutae 400g, Radix Angelicae Sinensis 400g,
Fructus psoaleae 120g, Cortex Eucommiae 160g, English walnut 50g, fructus sophorae 100g.
Specifically, further include dogwood fruit 100g, pilose antler 100g, pilose antler needs unhairing shortcake to process.
Above-mentioned raw materials are handled according to the method in embodiment 1, obtain sample 2.
Embodiment 3
A kind of Chinese medicine of prevention senile dementia, includes the bulk pharmaceutical chemicals of following parts by weight：Radix Polygoni Multiflori 500g, the white fleece-flower root
500g, root of bidentate achyranthes 220g, fushen 200g, poria cocos 450g, PORIA ALBA 450g, fruit of Chinese wolfberry 400g, Semen Cuscutae 400g, Radix Angelicae Sinensis 400g,
Fructus psoaleae 150g, Cortex Eucommiae 150g, English walnut 100g, fructus sophorae 100g.
Specifically, further include dogwood fruit 125g, pilose antler 100g, pilose antler needs unhairing shortcake to process.
Above-mentioned raw materials are handled according to the method in embodiment 1, obtain sample 3.
Embodiment 4
A kind of Chinese medicine of prevention senile dementia, includes the bulk pharmaceutical chemicals of following parts by weight：Radix Polygoni Multiflori 500g, the white fleece-flower root
500g, root of bidentate achyranthes 220g, fushen 200g, poria cocos 450g, PORIA ALBA 420g, fruit of Chinese wolfberry 410g, Semen Cuscutae 420g, Radix Angelicae Sinensis 450g,
Fructus psoaleae 150g, Cortex Eucommiae 150g, English walnut 100g, fructus sophorae 100g.
Specifically, further include dogwood fruit 125g, pilose antler 100g, pilose antler needs unhairing shortcake to process.
Above-mentioned raw materials are handled according to the method in embodiment 1, obtain sample 4.
Two, experimental data compares
2.1 animal packet
Mouse 60, weight 20g or so, half male and half female, random point 5 groups, every group 10, half male and half female, wherein two groups are
In addition control group, feeding chow diet give sample 1, sample 2, sample 3, sample 4 for four groups, 10-15 balls are added in feed respectively
Counter sample, three times a day, continuous feeding 30 days.
It is prepared by 2.2 animal models
Then be respectively adopted hyoscine cause Memory acquisition sexual dysfunction model, the 1h after last feeding, give sample 1,
Four groups of mouse of sample 2, sample 3, sample 4 carry out intraperitoneal injection scopolamine hydrobromide injection 3mg/kg, abdominal cavity note respectively
Beam product is 10ml/kg, and the mouse of one group of feeding chow diet carries out intraperitoneal injection hydrobromic acid east respectively as model control group
Hyoscyamine injection 3mg/kg, intraperitoneal injection volume are 10ml/kg, the blank control group injection of another group of normal foodstuff of feeding etc.
The physiological saline of capacity carries out Jumping test after 10min.
2.3 Jumping test
Jumping test case bottom is covered with copper grid as stimulating electrode, and right lateral side is placed a valve rubber and escaped as mouse in case
Keep away the safety zone of electric shock.First be put into rat and adapt to 5min, be subsequently passed 70V, 0.5A~0.7A electric currents, mouse shocked by electricity after just
Paradoxical reaction is to jump onto platform to hide noxious stimulation.Record the rat time used from be initially powered up appearing on the stage completely, for 24 hours after
It resurveys and tests once to survey memory capability.
2.4 data statistics
All data are indicated with (x ± s), are that difference is statistically significant with P ＜ 0.05.
Note：* P ＜ 0.01, * P ＜ 0.05
The above results are shown, compared with blank control group, the significant decline of model group ability of learning and memory illustrates model
It is successfully established, 1 group of sample, sample 2, sample 3,4 groups of sample are compared with model group, learning ability and the significant difference of memory capability
It is different, and be to decline, so Chinese traditional medicine composition of the present invention, has remarkable result for prevention senile dementia.
The present invention is not limited to the embodiment, anyone should learn that the structure made under the inspiration of the present invention becomes
Change, the technical schemes that are same or similar to the present invention are each fallen within protection scope of the present invention.
Technology that the present invention is not described in detail, shape, construction part are known technology.
Claims (6)
1. a kind of Chinese medicine of prevention senile dementia, it is characterised in that：Include the bulk pharmaceutical chemicals of following parts by weight：100 parts of Radix Polygoni Multiflori,
White 80-100 parts of the fleece-flower root, 40-50 parts of the root of bidentate achyranthes, 40-50 parts of fushen, 80-100 parts of poria cocos, 80-100 parts of PORIA ALBA, the fruit of Chinese wolfberry
40-50 parts, 40-50 parts of Semen Cuscutae, 40-50 parts of Radix Angelicae Sinensis, 24-30 parts of fructus psoaleae, 24-30 parts of Cortex Eucommiae, 10-20 parts of English walnut, the Fructus Sophorae
It is 10-20 parts sub-.
2. a kind of Chinese medicine of prevention senile dementia according to claim 1, it is characterised in that：Include the original of following parts by weight
Expect medicine：100 parts of Radix Polygoni Multiflori, 100 parts of the white fleece-flower root, 50 parts of the root of bidentate achyranthes, 50 parts of fushen, 100 parts of poria cocos, 100 parts of PORIA ALBA, Chinese holly
50 parts of matrimony vine, 50 parts of Semen Cuscutae, 50 parts of Radix Angelicae Sinensis, 25 parts of fructus psoaleae, 25 parts of Cortex Eucommiae, 20 parts of English walnut, 20 parts of fructus sophorae.
3. a kind of Chinese medicine of prevention senile dementia according to claim 1, it is characterised in that：Further include dogwood fruit 20-25
Part, 10-15 parts of pilose antler, pilose antler needs unhairing shortcake to process.
4. a kind of Chinese medicinal preparation method of prevention senile dementia, it is characterised in that：Include the following steps：
(1) 80-100 parts of Radix Polygoni Multifloris, the white fleece-flower root are weighed respectively, are impregnated in water in which rice has been washed, peeling is scraped with bamboo knife, be sliced, wherein
Water in which rice has been washed is third time or the 4th limpid water in which rice has been washed after rice washing；
(2) the 40-50 roots of bidentate achyranthes are weighed, Radix Polygoni Multiflori, the white fleece-flower root and black soya bean place mat after being impregnated with step (1) is middle, wherein certainly
Top to bottm is followed successively by one layer of root of bidentate achyranthes, one layer of black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean, in sand
Steam saturating 15min in pot, after cooling completely, remove out black soya bean, laying steams 15min, wherein be followed successively by from top to bottom one layer of root of bidentate achyranthes, one layer
Black soya bean, one layer of white fleece-flower root, one layer of black soya bean, one layer of Radix Polygoni Multiflori, one layer of black soya bean steam three times again repeatedly, remove black soya bean, stay altogether
Take Radix Polygoni Multiflori, the white fleece-flower root and the root of bidentate achyranthes；
(3) 40-50 parts of fushen is weighed, takes cow's milk or sheep breast to mix for use；
(4) 80-100 parts of poria cocos is weighed, cow's milk is taken to soak one night, weighs 80-100 parts of PORIA ALBA, sheep breast leaching one night dries；
(5) 40-50 parts of the fruit of Chinese wolfberry is weighed, steeping in wine, which is washed, to be dried；
(6) 40-50 parts of Semen Cuscutae is weighed, after steeping in wine, boiling 15min is dried
(7) 40-50 parts of Radix Angelicae Sinensis is weighed, steeping in wine one night dries；
(8) 24-30 parts of fructus psoaleae, stir-bake to yellowish are weighed；
(9) 10-20 parts of English walnut is weighed, is smashed to pieces such as mud；
(10) 24-30 parts of Cortex Eucommiae is weighed, cow's milk soaks one night, dries, silk is removed in quick-fried；
(11) 10-20 parts of fructus sophorae, stir-bake to yellowish color are weighed；
By the Radix Polygoni Multiflori left and taken in step (2), the white fleece-flower root, the root of bidentate achyranthes and step (3) to (11), treated, and raw material are put
Enter in the mill of non-ironware and be ground into smalls, honey is added to be smelt ball, ball size is 0.1-0.2 grams.
5. a kind of Chinese medicinal preparation method of prevention senile dementia according to claim 4, it is characterised in that：Honey is smelt ball
When, 20-25 parts of dogwood fruits, 10-15 parts of Pilose Antlers are added.
6. a kind of Chinese medicinal preparation method of prevention senile dementia according to claim 4, it is characterised in that：Step (1) is extremely
During the raw material disposal of step (11), it cannot be stained with ironware.
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| CN109481656A (en) * | 2018-11-23 | 2019-03-19 | 南阳理工学院 | A kind of drug for treating senile dementia |
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| CN102784359A (en) * | 2012-08-08 | 2012-11-21 | 冯安华 | Medicine for treating senile dementia and preparation method of medicine |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102784359A (en) * | 2012-08-08 | 2012-11-21 | 冯安华 | Medicine for treating senile dementia and preparation method of medicine |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109481656A (en) * | 2018-11-23 | 2019-03-19 | 南阳理工学院 | A kind of drug for treating senile dementia |
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