CN103861040B - A kind of medicine and preparation method for the treatment of renal colic - Google Patents
A kind of medicine and preparation method for the treatment of renal colic Download PDFInfo
- Publication number
- CN103861040B CN103861040B CN201410106211.3A CN201410106211A CN103861040B CN 103861040 B CN103861040 B CN 103861040B CN 201410106211 A CN201410106211 A CN 201410106211A CN 103861040 B CN103861040 B CN 103861040B
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- medicine
- radix
- renal colic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010038419 Renal colic Diseases 0.000 title claims abstract description 45
- 239000003814 drug Substances 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000004615 ingredient Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 241001506047 Tremella Species 0.000 claims abstract description 11
- 241000233779 Cyclocarya paliurus Species 0.000 claims abstract description 10
- 241000003857 Parmelia saxatilis Species 0.000 claims abstract description 9
- 240000005255 Rubus parvifolius Species 0.000 claims abstract description 9
- 235000018803 Rubus parvifolius Nutrition 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000000284 extract Substances 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000012153 distilled water Substances 0.000 claims description 9
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 9
- 238000012545 processing Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 4
- -1 boil 2 ~ 3 hours Substances 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 238000007598 dipping method Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 241000407170 Curcuma Species 0.000 claims 4
- 235000014375 Curcuma Nutrition 0.000 claims 4
- 235000005903 Dioscorea Nutrition 0.000 claims 4
- 241000234273 Dioscorea Species 0.000 claims 4
- 235000000504 Dioscorea villosa Nutrition 0.000 claims 4
- 241000305492 Gastrodia Species 0.000 claims 4
- 241000120647 Osbeckia Species 0.000 claims 4
- 241000208966 Polygala Species 0.000 claims 4
- 235000004879 dioscorea Nutrition 0.000 claims 4
- 208000002193 Pain Diseases 0.000 abstract description 32
- 230000036407 pain Effects 0.000 abstract description 31
- 210000004369 blood Anatomy 0.000 abstract description 27
- 239000008280 blood Substances 0.000 abstract description 27
- 210000003734 kidney Anatomy 0.000 abstract description 20
- 208000024891 symptom Diseases 0.000 abstract description 18
- 230000001737 promoting effect Effects 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 13
- 201000010099 disease Diseases 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 11
- 206010047700 Vomiting Diseases 0.000 abstract description 9
- 210000004243 sweat Anatomy 0.000 abstract description 7
- 208000004880 Polyuria Diseases 0.000 abstract description 6
- 230000035619 diuresis Effects 0.000 abstract description 6
- 230000036039 immunity Effects 0.000 abstract description 5
- 231100000957 no side effect Toxicity 0.000 abstract description 4
- 230000001225 therapeutic effect Effects 0.000 abstract description 4
- 238000010792 warming Methods 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 3
- 230000035876 healing Effects 0.000 abstract description 3
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 206010011224 Cough Diseases 0.000 description 16
- 210000004072 lung Anatomy 0.000 description 12
- 208000006673 asthma Diseases 0.000 description 10
- 108091006146 Channels Proteins 0.000 description 8
- 206010030113 Oedema Diseases 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 8
- 230000008961 swelling Effects 0.000 description 8
- 238000003745 diagnosis Methods 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 241000411851 herbal medicine Species 0.000 description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 208000026435 phlegm Diseases 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 208000004998 Abdominal Pain Diseases 0.000 description 5
- 208000006820 Arthralgia Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 208000001848 dysentery Diseases 0.000 description 5
- 208000014674 injury Diseases 0.000 description 5
- 235000012054 meals Nutrition 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 230000008736 traumatic injury Effects 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 4
- 208000005392 Spasm Diseases 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 231100000869 headache Toxicity 0.000 description 4
- 201000008383 nephritis Diseases 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 210000000626 ureter Anatomy 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 3
- 206010017553 Furuncle Diseases 0.000 description 3
- 208000000913 Kidney Calculi Diseases 0.000 description 3
- 208000008930 Low Back Pain Diseases 0.000 description 3
- 206010029148 Nephrolithiasis Diseases 0.000 description 3
- 208000025747 Rheumatic disease Diseases 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 206010015037 epilepsy Diseases 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 210000001624 hip Anatomy 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 3
- 230000000552 rheumatic effect Effects 0.000 description 3
- 208000004371 toothache Diseases 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 238000002562 urinalysis Methods 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- BGEBZHIAGXMEMV-UHFFFAOYSA-N 5-methoxypsoralen Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OC BGEBZHIAGXMEMV-UHFFFAOYSA-N 0.000 description 2
- 208000007743 Acute Abdomen Diseases 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010006458 Bronchitis chronic Diseases 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 208000004232 Enteritis Diseases 0.000 description 2
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010020524 Hydronephrosis Diseases 0.000 description 2
- 208000015817 Infant Nutrition disease Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 201000005702 Pertussis Diseases 0.000 description 2
- 206010053615 Thermal burn Diseases 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 206010047513 Vision blurred Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000036592 analgesia Effects 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 208000007451 chronic bronchitis Diseases 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000002934 diuretic Substances 0.000 description 2
- 230000001882 diuretic effect Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000006750 hematuria Diseases 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- IGWDEVSBEKYORK-UHFFFAOYSA-N isoimperatorin Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)C IGWDEVSBEKYORK-UHFFFAOYSA-N 0.000 description 2
- 210000000244 kidney pelvis Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- 206010044008 tonsillitis Diseases 0.000 description 2
- 239000002435 venom Substances 0.000 description 2
- 231100000611 venom Toxicity 0.000 description 2
- 210000001048 venom Anatomy 0.000 description 2
- ZPSAEGUNYMEKBP-UHFFFAOYSA-N 5-Isopentenyloxy-psoralen Natural products CC(C)C=COc1c2C=CC(=O)Oc2cc3occc13 ZPSAEGUNYMEKBP-UHFFFAOYSA-N 0.000 description 1
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 208000000197 Acute Cholecystitis Diseases 0.000 description 1
- BEYIWVKWKJROGZ-UHFFFAOYSA-N Alloimperatorin Natural products O1C(=O)C=CC2=C1C(O)=C1OC=CC1=C2OCC=C(C)C BEYIWVKWKJROGZ-UHFFFAOYSA-N 0.000 description 1
- 206010002515 Animal bite Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- DBMJZOMNXBSRED-UHFFFAOYSA-N Bergamottin Natural products O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)CCC=C(C)C DBMJZOMNXBSRED-UHFFFAOYSA-N 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 108090000312 Calcium Channels Proteins 0.000 description 1
- 102000003922 Calcium Channels Human genes 0.000 description 1
- 208000031868 Calculus ureteric Diseases 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 206010008614 Cholecystitis acute Diseases 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- BAHUBXAYVOCLNA-UHFFFAOYSA-N Isoangelol Natural products O1C(=O)C=CC2=C1C=C(OC)C(C(OC(=O)C(C)=CC)C(O)C(C)(C)O)=C2 BAHUBXAYVOCLNA-UHFFFAOYSA-N 0.000 description 1
- 208000008839 Kidney Neoplasms Diseases 0.000 description 1
- 241001313288 Labia Species 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- KGGUASRIGLRPAX-UHFFFAOYSA-N Meranzin hydrate Natural products C1=CC(=O)OC2=C(CC(O)C(C)(C)O)C(OC)=CC=C21 KGGUASRIGLRPAX-UHFFFAOYSA-N 0.000 description 1
- QXKHYNVANLEOEG-UHFFFAOYSA-N Methoxsalen Chemical compound C1=CC(=O)OC2=C1C=C1C=COC1=C2OC QXKHYNVANLEOEG-UHFFFAOYSA-N 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010028817 Nausea and vomiting symptoms Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 206010033647 Pancreatitis acute Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 241001662443 Phemeranthus parviflorus Species 0.000 description 1
- 241000219000 Populus Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 206010067868 Skin mass Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 206010044314 Tracheobronchitis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000000014 Ureteral Calculi Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- PCWZKQSKUXXDDJ-UHFFFAOYSA-N Xanthotoxin Natural products COCc1c2OC(=O)C=Cc2cc3ccoc13 PCWZKQSKUXXDDJ-UHFFFAOYSA-N 0.000 description 1
- HOBWAPHTEJGALG-JKCMADFCSA-N [(1r,5s)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfate Chemical compound [O-]S([O-])(=O)=O.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1 HOBWAPHTEJGALG-JKCMADFCSA-N 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 201000003229 acute pancreatitis Diseases 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229930183733 angelol Natural products 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001716 anti-fugal effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 229960002028 atropine sulfate Drugs 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960002045 bergapten Drugs 0.000 description 1
- KGZDKFWCIPZMRK-UHFFFAOYSA-N bergapten Natural products COC1C2=C(Cc3ccoc13)C=CC(=O)O2 KGZDKFWCIPZMRK-UHFFFAOYSA-N 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 230000023852 carbohydrate metabolic process Effects 0.000 description 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 201000001352 cholecystitis Diseases 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 201000003146 cystitis Diseases 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 239000002027 dichloromethane extract Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 201000003511 ectopic pregnancy Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 201000005619 esophageal carcinoma Diseases 0.000 description 1
- 238000002481 ethanol extraction Methods 0.000 description 1
- 230000000763 evoking effect Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 201000003265 lymphadenitis Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 208000007106 menorrhagia Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229960004469 methoxsalen Drugs 0.000 description 1
- SQBBOVROCFXYBN-UHFFFAOYSA-N methoxypsoralen Natural products C1=C2OC(=O)C(OC)=CC2=CC2=C1OC=C2 SQBBOVROCFXYBN-UHFFFAOYSA-N 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 208000025661 ovarian cyst Diseases 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Abstract
The invention discloses a kind of medicine and preparation method for the treatment of renal colic, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Herba Spilanthis Acmellae, Radix Polygalae, Cyclocarya paliurus Iljinskaja, Rhizoma Gastrodiae, Tremella, Caulis et folium gaultheriae yunnanensis, Herba Osbeckiae, Radix Curcumae, Herba Aristolochiae, Rhizoma Dioscoreae, Fructus Cnidii, Herba Peperomiae Dindygulensis, Rubus Parvifolius L., Radix Angelicae Pubescentis, Parmelia saxatilis Ach. and Herba Crotalariae Ferrugineae; Medicine of the present invention has effect of clearing away heat and promoting diuresis, promoting flow of QI and blood, expelling wind and removing dampness, warming the kidney to invigorate YANG, can alleviating pain, the nausea and vomiting caused for renal colic, dripping sweat, pale complexion, the symptom such as toss about and feel uneasy have significant therapeutic effect, and can improve body's immunity, promote graft function, short treating period, instant effect, cost is low, have no side effect, treating both the principal and secondary aspects of a disease, non-relapse after healing, can extensively promote should in the clinical treatment of renal colic.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of renal colic.
Background technology
Renal colic, also known as kidney, ureteral colic, is because certain cause of disease makes the acute partial outlet obstruction of renal pelvis, ureteral smooth muscle spasm or tube chamber cause, its generation and health whether strong irrelevant; Be characterized in breaking out and have an intense pain, pain from Ipsilateral waist along ureter to hypogastric region, the radiation of groin, femoribus internus, testis or labia, sustainable a few minutes or several tens minutes, even a few hours are not etc.Outbreak is often with nausea and vomiting, dripping sweat, pale complexion, the symptom such as toss about and feel uneasy, and severe patient can cause shock.
Because renal colic is often with the symptom of digestive tract such as Nausea and vomiting, abdominal distention, easy and acute abdomen is obscured, and therefore should note getting rid of following common acute abdomen in diagnosis: acute appendicitis, acute cholecystitis and acute pancreatitis; Torsion of the pedicle of ovarian cyst, ectopic pregnancy, acute salpinitis etc. except female patient also answers.Through routine urinalysis and ultrasound diagnosis, generally renal colic can be determined whether, wherein in routine urinalysis, " erythrocyte ++ " namely points out meaningful, if just one+or female patient are in intermenstrual period, this result just can not as diagnosis basis, can not Reusability analgesic before not obtaining making a definite diagnosis, otherwise the observation of impact to the state of an illness, even delay diagnosis.
Renal colic dependent a kind of disease, but a kind of symptom.With regard to occurrence regularity, renal colic is with hematuria, mostly caused by kidney and ureteral calculus, but this is not symptom specific to calculus, therefore after renal colic is alleviated, must check that the cause of disease does corresponding treatment further, otherwise following two large danger may be there are: first, can not Timeliness coverage urinary tract obstruction.The modal reason of renal colic is lithangiuria, and calculus incarceration in renal pelvis or ureter, not necessarily occurs angor sometimes, but can cause and block, and causes hydronephrosis in various degree.In the course of time, hydronephrosis can increase the weight of day by day, renal function is finally caused to be lost, in the process, patient only has the slight soreness of waist or does not have obvious symptom, easily out in the cold, someone does " mute " organ kidney ratio, be meant to self there has been more serious pathological changes, but do not have significant reaction, this is also the easy unheeded main cause of renal colic; Secondly, the diagnosis of the important diseases such as tumor of kidney, tuberculosis may be incured loss through delay.The nephrorrhagia of any reason, during as formed clot by ureter, all can stimulate ureter and spasm occurs, causing and block, occurring the angor as renal calculus.Therefore, calculus is can't see in the film making of renal colic postabdomen x-ray, and it is just no problem to be not equal to.
Current Chinese and western medicine has multiple medicine and method, but curative effect is very micro-, and some medicine takes effect slowly, and the course for the treatment of is long, also has side effect after using, and various big hospital is badly in need of a kind of simple, efficient, Chinese medicine formula of having no side effect.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of renal colic; Medicine of the present invention has effect of clearing away heat and promoting diuresis, promoting flow of QI and blood, expelling wind and removing dampness, warming the kidney to invigorate YANG, can alleviating pain, the nausea and vomiting caused for renal colic, dripping sweat, pale complexion, the symptom such as toss about and feel uneasy have significant therapeutic effect, and can improve body's immunity, promote graft function, short treating period, instant effect, cost is low, have no side effect, treating both the principal and secondary aspects of a disease, non-relapse after healing, can extensively promote should in the clinical treatment of renal colic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for renal colic, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Treat a preparation method for the medicine of renal colic, comprise following processing step:
(1) Herba Spilanthis Acmellae and Rhizoma Dioscoreae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Radix Polygalae, Cyclocarya paliurus Iljinskaja, Rhizoma Gastrodiae, Tremella, Radix Curcumae, Rubus Parvifolius L., Parmelia saxatilis Ach. and Herba Crotalariae Ferrugineae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Caulis et folium gaultheriae yunnanensis, Fructus Cnidii, Herba Peperomiae Dindygulensis and Radix Angelicae Pubescentis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by Herba Osbeckiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Herba Aristolochiae, dry, big fire is fried, parching to brown, takes out, grinds into powder, crosses 180 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the medicine for the treatment of renal colic of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Spilanthis Acmellae: acrid in the mouth, warm in nature.Detoxification and promoting urination, relieving cough and relieving asthma, reducing swelling and alleviating pain.For malaria, toothache, enteritis, dysentery, cough, asthma, pertussis, pulmonary tuberculosis.Venom is controlled in external, dog bite, carbuncle furuncle and phyma poison.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " relieving cough and relieving asthma, reducing swelling and alleviating pain.Cure cold cough, chronic bronchitis, asthma, pertussis, pulmonary tuberculosis, venom, sore swollen toxin, toothache.”
Radix Polygalae: warm in nature, bitter in the mouth, pungent; GUIXIN, kidney, lung meridian.To calm the nerves Fructus Alpiniae Oxyphyllae, eliminating phlegm for diminishing swelling.The insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain." Mingyi Bielu " carries: " centering gas, spasmolytic is throbbed with fear, benefit essence, goes heat in heart intake of food in the morning and vomitting in the evening gas, skin, appearance yellow.”
Cyclocarya paliurus Iljinskaja: there is many effects such as blood sugar lowering, blood fat reducing, blood pressure lowering, raising immunity.Modern medicine study confirms, cyclocarya paliurus tea is rich in the Organic nutrient such as abundant saponin, flavone, polysaccharide, can active balance human body carbohydrate metabolism, effective reduction triglyceride and cholesterol, there is the function of magical natural blood pressure lowering, blood sugar lowering, blood fat reducing, to enhancing body immunity, antioxidation, defying age, hepatoprotective etc., there is unique effect simultaneously, especially to diabetic population, have remarkable hypoglycemic effect.
Rhizoma Gastrodiae: sweet in the mouth, property is put down; Enter Liver Channel.Suppressing liver-wind to relieve spasm contraction, calmness, analgesia, convulsion, cure mainly dizziness and headache, and infantile convulsion is twitched.Modern medicine study confirms, Rhizoma Gastrodiae can improve the threshold value clicking spasm, can prevent again the outbreak of guinea pig experimental epilepsy.
Tremella: property is put down, sweet, light, nontoxic; Return lung, stomach, kidney channel.Nourishing is promoted the production of body fluid, lung moistening nourishing the stomach." pearl sac " carries: " stomach of foot Yang Ming, hands sun bright large intestine, lung meridian." modern medicine study confirmation, containing protein, fat and several amino acids, mineral and glycogen in Tremella, belong to colloidality fungus, be rich in selenium and other trace elements, have the function of radioprotective, spot-eliminating beauty treatment is effective simultaneously.Be applicable to the five internal organs weakness, insufficiency of vital energy and blood, lusterless complexion, hair not damp.According to the study, Tremella can make the metabolism of people strengthen, and blood circulation is vigorous, and the function of each histoorgan improves, and the elasticity of skin strengthens, and subcutaneous tissue is plentiful, and wrinkle shoals and even disappears, and skin becomes delicate smooth.
Caulis et folium gaultheriae yunnanensis: acrid in the mouth, warm in nature; Return lung, liver, kidney channel.Expelling wind and removing dampness, dispersing cold for relieving pain, promoting blood circulation to remove obstruction in the collateral, preventing phlegm from forming and stopping coughing.Cure mainly rheumatic arthralgia, cold syndrome of the stomach pain, traumatic injury, cough ant phlegm." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control phlegm-fire, bones and muscles pain, steep in wine good with it.Its stalk, washes anemofrigid-damp arthralgia, bones and muscles pain, warm bone is diathermanous, endures washing.”
Herba Osbeckiae: acrid in the mouth, light, property is put down; Return lung, spleen, liver, large intestine channel.Reduce phlegm dampness removing, hemostasis by removing blood stasis, removing toxic substances and promoting subsidence of swelling.Cure mainly cough, asthma, dysentery, have loose bowels, spit blood, spitting of blood, has blood in stool, amenorrhea, infantile malnutrition, rheumatic ostalgia, traumatic injury." Nanning City's medicine will " carries: " eliminating blood stasis to promote regeneration of blood, pain relieving restrains.Control interior external haemorrhage, infantile malnutrition, ulcerative gingivitis, toothache, cough.”
Radix Curcumae: acrid in the mouth, hardship, cold in nature; Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine." book on Chinese herbal medicine is stated " carries: " control heating, strongly fragrant, cough, bleeding from the gum, cough blood, hematuria, has a headache dizzy, mad epilepsy, dysentery, drenches, and the diseases such as eyes nose glossopharyngeum larynx.”
Herba Aristolochiae: circulation of qi promoting removing dampness, promoting blood circulation and stopping pain.Cure mainly stomachache, colicky, edema during pregnancy, puerperal, vim and vigour were suffered from abdominal pain, rheumatalgia, edema during pregnancy, and breast is suffered from abdominal pain, colic, rheumatalgia." book on Chinese herbal medicine is new again " carries: " removing heat from blood and promoting blood circulation, removes wind dampness removing, walk meridians, doublely controls the swollen pain of waist lower limb.”
Rhizoma Dioscoreae: sweet in the mouth, property is put down; Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst, loose stool of having loose bowels, leukorrhagia." detailed outline " carries: " stopping leak dysentery, reduce phlegm saliva, profit fur for kidney tonifying gas, strengthening the spleen and stomach.”
Fructus Cnidii: warm in nature, acrid in the mouth, hardship.Warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.Modern pharmacological research confirms, ethanol extraction has antifungic action.
Herba Peperomiae Dindygulensis: acrid in the mouth, cool in nature; Return lung, spleen, liver, kidney channel.Heat-clearing and toxic substances removing, blood stasis-eliminating and stagnation-dissipating, inducing diuresis to remove edema.Cure mainly lung-heat cough with asthma, measles, sore, cancerous protuberance, burn and scald, traumatic injury, oedema due to nephritis, gastric cancer, esophageal carcinoma, hepatocarcinoma, breast carcinoma, pulmonary carcinoma." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, detumescence dissipating blood stasis, pain relieving diuretic.Control traumatic injury, scald burn, carbuncle furuncle, oedema due to nephritis, pulmonary tuberculosis, asthma, tracheobronchitis, cough due to lung-heat.”
Rubus Parvifolius L.: bitter in the mouth, puckery, cool in nature.Clearing away heat and cooling blood, removing obstruction for relieving pain, inducing diuresis to remove edema.For cold, fever, laryngopharynx swelling and pain, spitting of blood, spits blood, dysentery, enteritis, hepatitis, hepatosplenomegaly, oedema due to nephritis, urinary system infection, calculus, menoxenia, leucorrhea, rheumatic ostalgia, treating swelling and pain by traumatic injury; Eczema is controlled in external, dermatitis.
Radix Angelicae Pubescentis: acrid in the mouth, hardship, tepor; Return liver, kidney, urinary bladder channel.Expelling wind and dampness, dispersing cold for relieving pain, for anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache, headache analgesic." Bencao Tujing " carries: " the auxiliary Radix Angelicae Pubescentis of Ramulus Mori, Radix Angelicae Pubescentis searches wind, dissipating cold pain relieving and blood stasis dispelling; Ramulus Mori wind-damp dispelling and the meridian dredging walks crosswise extremity.Papillary, treatment anemofrigid-damp arthralgia function strengthens, especially upper extremity pain, scapulohumeral periarthritis." modern medicine study confirmation; the platelet aggregation that angelol extract can suppress ADP external evoked; dichloromethane extract has the activity of antagonize calcium channel blocker receptor; the bergapten included, xanthotoxin, isoimperatorin have obvious spasmolysis, has analgesia, calmness, antiinflammatory, antibacterial action in addition.
Parmelia saxatilis Ach.: sweet in the mouth, cold in nature; Return liver, kidney channel.Nourishing blood for improving eyesight, the kidney invigorating diuresis, heat-clearing and toxic substances removing.Cure mainly blurred vision, spit blood, metrorrhagia, lumbocrural pain, urine burning pain, nebulousurine, leucorrhea, burn." the conventional Chinese herbal medicine handbook in the north " carries: " strengthening bone and muscle, eliminate indigestion gathers for nourishing blood for improving eyesight, benefit essence.Control blurred vision, lumbago and skelalgia, enclosed mass in abdomen, hepatitis.”
Herba Crotalariae Ferrugineae: bitter in the mouth, micro-acid, property is flat, cold; Return lung meridian.Nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Cure mainly tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin." choosing of Yunnan Chinese herbal medicine " carries: " diuretic, antiinflammatory are relievingd asthma, cough-relieving.Control chronic nephritis, cystitis, chronic bronchitis, tonsillitis, lymphadenitis, renal calculus, menoxenia, dysmenorrhea.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has effect of clearing away heat and promoting diuresis, promoting flow of QI and blood, expelling wind and removing dampness, warming the kidney to invigorate YANG, can alleviating pain, and the nausea and vomiting caused for renal colic, dripping sweat, pale complexion, the symptom such as toss about and feel uneasy have significant therapeutic effect.
2, medicine of the present invention can improve body's immunity, and promote graft function, short treating period, instant effect, cost is low, has no side effect, treating both the principal and secondary aspects of a disease, non-relapse after healing, and can extensively promote should in the clinical treatment of renal colic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Treat a preparation method for the medicine of renal colic, comprise following processing step:
(1) Herba Spilanthis Acmellae and Rhizoma Dioscoreae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Radix Polygalae, Cyclocarya paliurus Iljinskaja, Rhizoma Gastrodiae, Tremella, Radix Curcumae, Rubus Parvifolius L., Parmelia saxatilis Ach. and Herba Crotalariae Ferrugineae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Caulis et folium gaultheriae yunnanensis, Fructus Cnidii, Herba Peperomiae Dindygulensis and Radix Angelicae Pubescentis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by Herba Osbeckiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Herba Aristolochiae, dry, big fire is fried, parching to brown, takes out, grinds into powder, crosses 180 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the medicine for the treatment of renal colic of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5
g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover; The person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of renal colic, select the routine clinical observation of renal colic patient 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 56 example, women 44 example, 30 ~ 75 years old age, 52.5 years old mean age, the shortest person of the course of disease 3 months, most elder 7 years, average 3.5 years.Matched group 100 example, wherein male 57 example, women 43 example, 31 ~ 76 years old age, 53.7 years old mean age, the shortest person of the course of disease 4 months, most elder 8 years, average 4.1 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes Atropine Sulfate Tablets, oral, be grown up one time 2,3 times on the one, warm water delivery service after meal.
3, efficacy determination:
(1) cure: pain symptom all disappears, physical recovery is normal, and body index recovers normal on inspection.
(2) effective: pain symptom disappears, and body index recovers normal substantially on inspection.
(3) effective: pain symptom disappears substantially, body index part takes a turn for the better on inspection.
(4) invalid: by treating rear pain symptom without being clearly better.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Wei, man, 33 years old, Yuncheng, Shanxi people.Patient's Upper abdominal pain, time have Nausea and vomiting symptom to occur, abdominal pain is unbearably sometimes, removes hospital admission, is diagnosed as renal colic through doctor, uses many medicines, only serves temporary pain relieving, will recur after a time, can not fully recover.To our hospital, take said medicine of the present invention, after taking 1 course for the treatment of, pain symptom obviously disappears, and fully recovers, follow up a case by regular visits to, do not recur so far after taking the 2nd course for the treatment of.
2, Tan, female, 26 years old, people from Dalian.Patient suffers from renal colic, and often outbreak is normal with vomiting, dripping sweat, hurt like hell, loses improvement after treatment a period of time.To our hospital afterwards, take said medicine of the present invention, after taking 2 courses for the treatment of, vomiting, dripping sweat, hurt like hell obviously alleviate, and after taking the 3rd course for the treatment of, renal colic is cured.
3, dragon certain, man, 45 years old, people from Yangzhou, Jiangsu.Patient suffers from renal colic, and as lancinating, also often to ache together with thigh root with lower abdomen, have the symptom of vomiting, do not feel like eating whatever, used multiple method to treat, curative effect is very poor.Front to our hospital, take medicine of the present invention, after taking 1 course for the treatment of, renal colic obviously alleviates, and after continuing to take 1 course for the treatment of, renal colic is cured, and follows up a case by regular visits to without recurrence after 1 year.
4, multitude, female, 37 years old, Taizhou of Zhejiang people.Patient suffers from renal colic, and with nausea and vomiting, dripping sweat, pale complexion, the symptom such as toss about and feel uneasy during outbreak, severe patient can cause shock, and go the hospitalize of to too much home, therapeutic effect is very poor.To our hospital afterwards, take medicine of the present invention, after taking 1 course for the treatment of, renal colic agent, obviously alleviates, and after taking the 5th course for the treatment of, renal colic is thoroughly cured.
5, Wang, man, 38 years old, Jinan, Shandong Province people.Patient suffers from nephropathy for many years, and be admitted to hospital and detect creatinine 260, blood urea nitrogen 18, urine protein 3+++, ERY 3+++, once took the equal inefficacy of various Drug therapy, and renal colic is serious.Rear patient symptom after doctor recommends to start to take 1 course for the treatment of of Chinese medicine preparation of the present invention has obvious alleviation, fully recovers, follow up a case by regular visits to, do not recur so far after 3 courses for the treatment of.
6, poplar, female, 42 years old, individual Liaoning people from Shenyang.Patient suffers from chronic nephritis and hypertension, lower limbs edema seriously and accompany the symptom such as the puffiness of the eyes, lumbago, dizziness, weak, tinnitus, and with renal colic.Admission examination, routine urinalysis display albumen 3+, RBC1+, granular cast 2-3, routine blood test display HBG11g/dl.Take 2 courses for the treatment of of medicine of the present invention, health take a favorable turn, and fully recovers, follow up a case by regular visits to and have no recurrence after 3 courses for the treatment of.
Claims (5)
1. treat a medicine for renal colic, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
26 ~ 61 parts, Herba Spilanthis Acmellae 36 ~ 71 parts of Radix Polygalaes 31 ~ 66 parts of Cyclocarya paliurus Iljinskaja 31 ~ 61 parts of Rhizoma Gastrodiaes
Tremella 26 ~ 56 parts of Caulis et folium gaultheriae yunnanensiss 26 ~ 56 parts of Herba Osbeckiaes 21 ~ 51 portions of Radix Curcumaes 21 ~ 51 parts
Herba Aristolochiae 21 ~ 46 portions of Rhizoma Dioscoreaes 21 ~ 46 parts of Fructus Cnidiis 16 ~ 41 parts of Herba Peperomiae Dindygulensiss 16 ~ 41 parts
Rubus Parvifolius L. 11 ~ 41 parts of Radix Angelicae Pubescentiss 11 ~ 41 parts of Parmelia saxatilis Ach. 11 ~ 36 parts of Herba Crotalariae Ferrugineaes 6 ~ 31 parts.
2. a kind of medicine for the treatment of renal colic according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
31 ~ 56 parts, Herba Spilanthis Acmellae 41 ~ 66 parts of Radix Polygalaes 36 ~ 61 parts of Cyclocarya paliurus Iljinskaja 36 ~ 56 parts of Rhizoma Gastrodiaes
Tremella 31 ~ 51 parts of Caulis et folium gaultheriae yunnanensiss 31 ~ 51 parts of Herba Osbeckiaes 26 ~ 46 portions of Radix Curcumaes 26 ~ 46 parts
Herba Aristolochiae 26 ~ 41 portions of Rhizoma Dioscoreaes 26 ~ 41 parts of Fructus Cnidiis 21 ~ 36 parts of Herba Peperomiae Dindygulensiss 21 ~ 36 parts
Rubus Parvifolius L. 16 ~ 36 parts of Radix Angelicae Pubescentiss 16 ~ 36 parts of Parmelia saxatilis Ach. 16 ~ 31 parts of Herba Crotalariae Ferrugineaes 11 ~ 26 parts.
3. a kind of medicine for the treatment of renal colic according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
36 ~ 51 parts, Herba Spilanthis Acmellae 46 ~ 61 parts of Radix Polygalaes 41 ~ 57 parts of Cyclocarya paliurus Iljinskaja 41 ~ 52 parts of Rhizoma Gastrodiaes
Tremella 36 ~ 46 parts of Caulis et folium gaultheriae yunnanensiss 36 ~ 46 parts of Herba Osbeckiaes 31 ~ 41 portions of Radix Curcumaes 31 ~ 41 parts
Herba Aristolochiae 31 ~ 36 portions of Rhizoma Dioscoreaes 31 ~ 36 parts of Fructus Cnidiis 26 ~ 31 parts of Herba Peperomiae Dindygulensiss 26 ~ 31 parts
Rubus Parvifolius L. 21 ~ 31 parts of Radix Angelicae Pubescentiss 21 ~ 31 parts of Parmelia saxatilis Ach. 21 ~ 26 parts of Herba Crotalariae Ferrugineaes 16 ~ 21 parts.
4. a kind of medicine for the treatment of renal colic according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
43 parts, Herba Spilanthis Acmellae 53 parts of Radix Polygalaes 49 parts of Cyclocarya paliurus Iljinskaja 46 parts of Rhizoma Gastrodiaes
Tremella 41 parts of Caulis et folium gaultheriae yunnanensiss 41 parts of Herba Osbeckiaes 36 portions of Radix Curcumaes 36 parts
Herba Aristolochiae 34 portions of Rhizoma Dioscoreaes 33 parts of Fructus Cnidiis 29 parts of Herba Peperomiae Dindygulensiss 29 parts
Rubus Parvifolius L. 26 parts of Radix Angelicae Pubescentiss 26 parts of Parmelia saxatilis Ach. 24 parts of Herba Crotalariae Ferrugineaes 19 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of renal colic, it is characterized in that: comprise following processing step:
(1) Herba Spilanthis Acmellae and Rhizoma Dioscoreae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(2) Radix Polygalae, Cyclocarya paliurus Iljinskaja, Rhizoma Gastrodiae, Tremella, Radix Curcumae, Rubus Parvifolius L., Parmelia saxatilis Ach. and Herba Crotalariae Ferrugineae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Caulis et folium gaultheriae yunnanensis, Fructus Cnidii, Herba Peperomiae Dindygulensis and Radix Angelicae Pubescentis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 85% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by Herba Osbeckiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) cleaned by Herba Aristolochiae, dry, big fire is fried, parching to brown, takes out, grinds into powder, crosses 180 order fine powders, for subsequent use;
(6) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the medicine of described treatment renal colic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410106211.3A CN103861040B (en) | 2014-03-21 | 2014-03-21 | A kind of medicine and preparation method for the treatment of renal colic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410106211.3A CN103861040B (en) | 2014-03-21 | 2014-03-21 | A kind of medicine and preparation method for the treatment of renal colic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103861040A CN103861040A (en) | 2014-06-18 |
| CN103861040B true CN103861040B (en) | 2016-03-30 |
Family
ID=50900428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410106211.3A Expired - Fee Related CN103861040B (en) | 2014-03-21 | 2014-03-21 | A kind of medicine and preparation method for the treatment of renal colic |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103861040B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647917A (en) * | 2009-07-09 | 2010-02-17 | 蒋勇 | Traditional Chinese medicine externally-applied anaesthetic |
| CN102327580A (en) * | 2011-09-19 | 2012-01-25 | 重庆市南川区瑞丰农业开发有限责任公司 | Traditional Chinese medicine for treating osteoarticular tuberculosis |
| CN102961566A (en) * | 2012-12-16 | 2013-03-13 | 李莉 | Navel compressing agent for treating irritable bowel syndrome |
-
2014
- 2014-03-21 CN CN201410106211.3A patent/CN103861040B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101647917A (en) * | 2009-07-09 | 2010-02-17 | 蒋勇 | Traditional Chinese medicine externally-applied anaesthetic |
| CN102327580A (en) * | 2011-09-19 | 2012-01-25 | 重庆市南川区瑞丰农业开发有限责任公司 | Traditional Chinese medicine for treating osteoarticular tuberculosis |
| CN102961566A (en) * | 2012-12-16 | 2013-03-13 | 李莉 | Navel compressing agent for treating irritable bowel syndrome |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103861040A (en) | 2014-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101797326B (en) | Chinese materia medica preparation for treating borborygmus diarrhoea and preparation method thereof | |
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN103099959B (en) | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof | |
| CN103751482B (en) | A kind of medicine and preparation method being used for the treatment of puerperal abdonimal pain | |
| CN102772781A (en) | Traditional Chinese medicine preparation for treating chronic colitis and preparation method thereof | |
| CN103920051B (en) | A kind of medicine and preparation method for the treatment of infantile malnutrition | |
| CN104548049A (en) | Traditional Chinese medicine composition for treating senile osteoporosis and preparation method thereof | |
| CN104524286A (en) | Traditional Chinese medicinal liquid for treating adverse reaction after anesthesia and preparation method | |
| CN103239692B (en) | Chinese medicine liniment for treating skin itch and preparation method of Chinese medicine liniment | |
| CN103861040B (en) | A kind of medicine and preparation method for the treatment of renal colic | |
| CN105147956A (en) | Traditional Chinese medicine for treating acute peptic ulcer bleeding and preparation method of traditional Chinese medicine | |
| CN104547384A (en) | Oral liquid for treating paraquat poisoning and preparation method of oral liquid | |
| CN104147277A (en) | Traditional Chinese medicinal preparation for treating myasthenia gravis and preparation method | |
| CN104997956A (en) | Behcet's syndrome and treatment drug thereof | |
| CN104383152A (en) | Traditional Chinese medicine preparation for treating glaucoma and preparation method of traditional Chinese medicine preparation | |
| CN103877390A (en) | Traditional-Chinese-medicine preparation for treating rheumatic fever and preparation method thereof | |
| CN104435865B (en) | Traditional Chinese medicine for treating arrhythmia and preparation method thereof | |
| CN103721157B (en) | A kind of Chinese medicine preparation for the treatment of functional dyspepsia | |
| CN103341054B (en) | Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof | |
| CN103610916B (en) | Traditional Chinese medicine preparation for treating arteriosclerosis | |
| CN103520644B (en) | Traditional Chinese medicine composition used for treating phlegm stagnation type hyperlipidaemia and preparation method of composition | |
| CN105663828A (en) | Medicine for treating postnatal depression and preparation method | |
| CN104474353A (en) | Medicine for treating myasthenia gravis and preparation method of medicine | |
| CN104784587A (en) | Traditional Chinese medicine composition for treating endocrine disorder type infertility and preparation method thereof | |
| CN103893706B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of coronary heart disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Hua Inventor after: Lv Ronghua Inventor before: Zheng Xiufen Inventor before: Zhang Wenying Inventor before: Fu Guangsheng |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160301 Address after: 261500 Gaomi City Hospital of traditional Chinese medicine, Fenghuang street, Weifang, Shandong, China, No. 588,, China Applicant after: Li Hua Address before: The 262600 Shandong city of Weifang province Linqu County Road No. 21 people's Hospital of Linqu County Applicant before: Zheng Xiufen |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Xu Xiangli Inventor before: Li Hua Inventor before: Lv Ronghua |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170829 Address after: 502 room 4, unit 17, 6 District, Langfang Pipeline Bureau, Hebei 065000, China Patentee after: Xu Xiangli Address before: 261500 Gaomi City Hospital of traditional Chinese medicine, Fenghuang street, Weifang, Shandong, China, No. 588,, China Patentee before: Li Hua |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160330 Termination date: 20180321 |