CN107789521A - It is a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia - Google Patents

It is a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia Download PDF

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CN107789521A
CN107789521A CN201711048417.5A CN201711048417A CN107789521A CN 107789521 A CN107789521 A CN 107789521A CN 201711048417 A CN201711048417 A CN 201711048417A CN 107789521 A CN107789521 A CN 107789521A
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blood
eye
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liver
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张西洁
金光明
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Abstract

Alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia the invention discloses a kind of, including patch eye position and positioned at the patch symmetrically arranged fixed side arm in eye position both sides, the patch eye position is made up of the zone of heating and Chinese traditional medicine composition nitride layer and nonwoven gauze for bonding connection successively from outside to inside, the surrounding of patch eye position is provided with contact, and small magnet is fixed with contact;The end of the fixed side arm is provided with the magnetic clasp being mutually matched.The eye sticker of the present invention controls illness in eye with Chinese medicine and magnetotherapy is combined, and traditional Chinese medicinal components alleviate kopiopia, treatment myopia from protect liver, strong kidney, invigorating the spleen and stomach, nourishing heart;Meanwhile by heating and magnetotherapy effect, drug effect is preferably reached eye everywhere, more effectively reach and alleviate kopiopia, the purpose for the treatment of myopia.

Description

It is a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia
Technical field
It is especially a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia the present invention relates to the field of Chinese medicines.
Background technology
With the work of modern, study, the prosperity of the increase of life stress, particularly network, make large quantities of netizen's eyes Fatigue can't bear, is dry and astringent unbearable, cause visual fatigue.Visual fatigue is a kind of common disease of current ophthalmology, and the symptom of patient is a variety of more Sample, common are near work can not be lasting, go out to lose face and eye socket around pain, blurred vision, eyes are dry and astringent, shed tears, Severe patient's headache, nausea, dizziness.Absent minded, decrease of memory, poor appetite and neck shoulder aching pain in waist and back and refer to pass Whole body syndrome, the small number of patients such as section numbness may occur in which diplopia, stereoscopic vision dysfunction, intraocular pressure rise, corneal injury etc., blue or green Teenager myopia can also occurs or deepen original myopic degree.There are glaucoma, eye surface or anterior ocular segment disease patient can also be because of eye Fatigue and trigger or aggravate original illness in eye.Doctor's general recommendations sees that each hour of computer is rested 5 minutes, does for daily twice Eye exercises.But it can almost accomplish to remind oneself rest to look far into the distance per hour without young netizen.In addition daily life system is irregular Change with dietary structure easily causes get angry insomnia, burden of liver exacerbation, liver blood occurs and loses foster, the dry and astringent swelling of eyes, eyesight The ophthalmic uncomfortable symptom such as decline, blurred vision.The traditional Chinese medical science thinks that the liver being in charge of the eyes " liver-QI being connected with eyes, then liver and mesh can distinguish the five colors ".Liver Dirty lesion often has influence on eyes.Such as deficiency of liver-blood, then binocular dryness, blurring of vision or yctalopia:Wind-heat of liver channel, it is seen that mesh Red pain of itching:Liver-fire flaming, it is seen that keratoconjunctivitis;Liver-yang hyperactivity, then vertigo;Liver wind agitation, it is seen that mesh is tiltedly upper to be regarded etc..Therefore Mesh is closely bound up with liver.
Eye drops is to treat one of the most frequently used article of eyes, but eye drops contains excessive chemical composition after all, such as Fruit is for a long time using can cause intraocular to be infected so that intraocular cell can not normally carry out metabolism so that eyes There is phenomena such as blurred vision is unclear.The traditional Chinese medical science conducts extensive research for this symptom, application number 2006100461465 Chinese patent discloses a kind of Chinese medicine preparation for treating kopiopia, mainly by Radix dactylicapni (Radix Dactylicapnotis) total alkaloids 1-10g, gel for eye use base Matter 0.1-20g and the mixing of appropriate water, stirring, pH value are adjusted to 4-9 with PH conditioning agents, 1000ml is injected water to, stirs Uniformly it is prepared into gel to produce, the invention uses anti-kopiopia medicine Radix dactylicapni (Radix Dactylicapnotis) total alkaloids as active component, using water solubility Gel is matrix, is formd with eye slow releasing function and good biocompatibility gel, has sustained release, comfortable, stimulation phase To less advantage.But the stimulation to eye still be present.The Chinese patent of application number 2016107557848 discloses One kind is clear liver and improved vision Chinese medicine composition, including cassia seed 5-12 parts, chrysanthemum 4-10 parts, hawthorn 2-6 parts and radix glycyrrhizae 1-4 parts, also May further include Buddha's hand 4-7 parts, lily 3-6 parts, purslane 2-5 parts and ginger 1-4 parts, can preferably to alleviate eyesight tired Labor, teenage pseudomyopia is treated, but curative effect is relatively single, effect is not satisfactory.
The content of the invention
In view of this, the purpose of the present invention is in view of the shortcomings of the prior art, there is provided one kind alleviates kopiopia, treatment myopia Compound traditional Chinese medicine composite eye sticker, from Chinese medicine Overall View and coordinate sight, from nourishing the liver, protect liver, enter with reference to magnetic therapy theory And reach and alleviate kopiopia, the effect for the treatment of myopia.
To reach above-mentioned purpose, the present invention uses following technical scheme:
It is a kind of alleviate kopiopia, treatment myopia compound traditional Chinese medicine composite eye sticker, including patch eye position and positioned at patch eye Position both sides symmetrically arranged fixed side arm, the patch eye position by bonding the zone of heating and Chinese traditional medicine composition of connection successively from outside to inside Nitride layer and nonwoven gauze composition, the surrounding of patch eye position are provided with contact, small magnet are fixed with contact;The fixed side arm End is provided with the magnetic clasp being mutually matched;
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 85-95% Chinese medical extracts, the transdermal rush of 5-15% Enter agent;
The composition and its parts by weight of the raw material of the Chinese medicine composition are as follows, peppermint 100-150 parts, black rice 100-120 Part, rhizome of chuanxiong 100-120 parts, borneol 100-120 parts, Paper mulberry Fruit 100-120 parts, leatherleaf mahonia 100-120 parts, crowtoe 80-100 Part, fruit of Chinese wolfberry 80-100 parts, cassia seed 80-100 parts, honeysuckle 80-100 parts, root of herbaceous peony 80-100 parts, mulberry leaf 60-80 parts, peanut Leaf 60-80 parts, magnetite 60-80 parts, lotus seeds 60-80 parts, durian 30-50 parts, Radix Astragali 30-50 parts, pseudo-ginseng 30-50 parts, cicada slough 30- 50 parts, ant 30-50 parts, safflower 30-50 parts, Fructus Corni 30-50 parts and radix glycyrrhizae 10-15 parts.
Further, the composition of the Chinese medicine material and its parts by weight are as follows, peppermint 120-130 parts, black rice 105-115 Part, rhizome of chuanxiong 105-115 parts, borneol 105-115 parts, Paper mulberry Fruit 105-115 parts, leatherleaf mahonia 105-115 parts, crowtoe 85-95 parts, Fruit of Chinese wolfberry 85-95 parts, cassia seed 85-95 parts, honeysuckle 85-95 parts, root of herbaceous peony 85-95 parts, mulberry leaf 65-75 parts, peanut leaf 65-75 Part, magnetite 65-75 parts, lotus seeds 65-75 parts, durian 35-45 parts, Radix Astragali 35-45 parts, pseudo-ginseng 35-45 parts, cicada slough 35-45 parts, ant Ant 35-45 parts, safflower 35-45 parts, Fructus Corni 35-45 parts and radix glycyrrhizae 12-15 parts.
Further, the composition of the Chinese medicine material and its parts by weight are as follows, 125 parts of peppermint, 110 parts of black rice, rhizome of chuanxiong 110 parts, 110 parts of borneol, 110 parts of Paper mulberry Fruit, 110 parts of leatherleaf mahonia, 90 parts of crowtoe, 90 parts of the fruit of Chinese wolfberry, 90 parts of cassia seed, gold and silver Spend 90 parts, 90 parts of the root of herbaceous peony, 70 parts of mulberry leaf, 70 parts of peanut leaf, 70 parts of magnetite, 70 parts of lotus seeds, 40 parts of durian, 40 parts of the Radix Astragali, pseudo-ginseng 15 parts of 40 parts, 40 parts of cicada slough, 40 parts of ant, 40 parts of safflower, 40 parts of Fructus Corni and radix glycyrrhizae.
Further, the transdermal enhancer is the ethanol solution that mass fraction is 3-5% Laurocaprams.
The preparation method of the Chinese traditional medicine composition nitride layer, comprises the following steps,
S1:By the peppermint, rhizome of chuanxiong, the Radix Astragali and borneol, Ultramicro-powder, CO are crushed2Supercritical extract, entrainment is used as using ethanol Agent, extract are concentrated and dried, are standby;
S2:The black rice, mulberry leaf, peanut leaf and durian are crushed, add volume fraction 35-45% ethanol water, 35-45 DEG C of ultrasonic extraction 30-40min, power 1000-2000W, extract are concentrated and dried, are standby;
S3:By the fruit of Chinese wolfberry, cassia seed, honeysuckle, the root of herbaceous peony, safflower, Fructus Corni, Paper mulberry Fruit, leatherleaf mahonia, crowtoe Crushed with radix glycyrrhizae, immersion, refluxing extraction, reclaim phegma, merged, concentration, drying for standby;
S4:The cicada slough, ant, pseudo-ginseng and lotus seeds are baked, crushed into powder shape;
S5:S1, S2, S3 and S4 products therefrom are mixed, add transdermal penetration agent, magnetite is uniformly applied in polyurethane film Portion, and the barrier paper gluing that shape size and polyurethane film are matched is thereon, both.
Further, extracting pressure in S1:25-30Mpa, concentration of alcohol 95%, solid-to-liquid ratio:5-5.5:1, extraction temperature is 500C, extraction time are that 4h rate of flow of fluids are 35kg/h;
Further, the refluxing extraction in S3 particularly, adds the volume parts 75-85% ethanol of 2-3 times of parts by weight Immersion, refluxing extraction 20-30 minutes, separate fraction and filter residue;Filter residue is added to the clear water of 2-3 times of parts by weight, and instills volume Fraction is 1% acetic acid, stirring, immersion, refluxing extraction 20-30 minutes, reclaims phegma, merges, concentration, drying for standby.
The pharmacological effect of traditional Chinese medicinal components is as follows:
Peppermint
Meridian distribution of property and flavor:Acrid flavour, it is cool in nature;Return lung, Liver Channel.
Effect:Effect:Relieving the exterior syndrome with drugs pungent in flavor and cool in property Chinese medicine peppermint has diverging wind-heat, head clearing, relieving sore-throat, promoting eruption.Cure mainly:For Syndrome of superficies attacked by wind-heat, headache and hot eyes, abscess of throat, measles without adequate eruption, rubella itch.
Black rice,
Meridian distribution of property and flavor:It is mild-natured, it is sweet;Return liver,kidney,spleen, stomach.
Effect:Black rice have appetizing benefit in, invigorating the spleen promoting blood circulation, improving eyesight the effect of.Can anti-aging;Supplement the albumen that human body needs The multi minerals such as matter, manganese, zinc provide.
The nutritive value of black rice
1. black rice is containing the nutrition such as protein, carbohydrate, B family vitamin, vitamin E, calcium, phosphorus, potassium, magnesium, iron, zinc member Element, it is nutritious.
2. the inorganic salts such as manganese, zinc, copper contained by black rice are mostly higher than rice 1~3 times;The vitamin more lacked containing rice C, the special composition such as chlorophyll, anthocyanidin, carrotene and cardiac glycoside, thus black rice has more nutrition than general rice.
Rhizome of chuanxiong
Meridian distribution of property and flavor:It is pungent, temperature.Return liver, courage, pericardium channel.
Effect:Blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, positive head wind headache, abdominal mass is suffered from abdominal pain, chest side of body shouting pain, Tumbling and swelling, headache, arthralgia pain due to rheumatism.Ligusticum wallichii can expand smooth muscle, improve microcirculation, and have anti-freezing, resistant to aggregation effect, and pass through Expand peripheral vessel and be depressured.
Borneol
Meridian distribution of property and flavor:Cold in nature, acrid flavour, hardship;Thoughts of returning home warp, the spleen channel, lung channel.
Effect, lead to all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving.
Cure mainly, control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid Sore, mesh also screen film, enterobiasis.
Paper mulberry Fruit
Meridian distribution of property and flavor:It is sweet, it is cold in nature;Enter liver, spleen, kidney channel.
Major function:Kidney tonifying clearing liver, improving eyesight, diuresis.For soreness and weakness of waist and knees, consumptive disease hectic fever due to yin, sand swoon blurred vision, raw screen film of mesh, Oedema turgor.
Leatherleaf mahonia
Meridian distribution of property and flavor:It is cold in nature, bitter.Return liver warp, stomach, large intestine channel.
Effect and effect:Heat-clearing and damp-drying drug, purging intense heat and detonicating.
Crowtoe
Meridian distribution of property and flavor:It is sweet, bitter;It is slightly cold;Return lung passes through.
Effect:Qi-restoratives;Heat-clearing;Quench the thirst.
Cure mainly:Consumptive disease;Fever due to yin deficiency;It is thirsty, can be with relieving cough and asthma.Crowtoe has well for cough due to wind-heat evil and pharyngitis Effect.
The fruit of Chinese wolfberry
Meridian distribution of property and flavor:Flat property and sweet taste;Return liver, kidney channel.
Effect:It is nourishing liver and kidney, benefiting shrewd head.For:Consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, Blood deficiency chlorosis, blurred vision.
Cassia seed
Meridian distribution of property and flavor:It is sweet, bitter, cold nature;Return large intestine channel.
Effect:1. heat-clearing improving eyesight, the red eye, swell pain caused by liver-fire flaming is controlled, often it is equal with selfheal, yncaria stem with hooks, chrysanthemum With;Red eye, swell pain, the more tears of photophobia caused by being rushed in wind-heat, are often equal with the seed of feather cockscomb, Semen Leonuri, chrysanthemum and use;Caused mesh is attacked in heat toxin Red puckery pain, it can be equal with radix scutellariae, the radix paeoniae rubrathe, scouring rush and use.2. relax bowel with control interior warmheartedness it is dry caused by constipation, often with fire fiber crops Benevolence, Snakegourd Seed are equally used.
Honeysuckle
Meridian distribution of property and flavor:It is sweet, it is cold in nature;Return lung, the heart, stomach, large intestine channel.
Effect:1. clearing heat and detoxicating, with controlling warm disease from the beginning of body is warm, thirsty, rapid pulse, is often equal with the capsule of weeping forsythia, Radix Isatidis With;Sore carbuncle with dandelion, chrysanthemum indicum, Chinese violet from the beginning of red and swollen heat pain, being often equal and use.2. dispelling wind and heat from the body, with controlling affection of exogenous wind-heat Exterior syndrome, often it is equal with the capsule of weeping forsythia, peppermint, Lasiosphaera fenzlii and uses.3. removing heat from the blood and relieve diarrhea, with toxic-heat and blood stasis are controlled, it is equivalent purslane, the Chinese bulbul can be matched somebody with somebody With.
The root of herbaceous peony
Meridian distribution of property and flavor:Bitter, acid, cold nature;Return liver, the spleen channel.
Effect:Effect:The moon, soft liver analgesic, suppressing liver-YANG are held back in blood-nourishing.Cure mainly:For irregular menstruation, uterine bleeding, abnormal sweating, Gastral cavity abdomen shoot, pain over the hypochondriac region, four limbs contraction pain, dizziness of having a headache.
Mulberry leaf
Meridian distribution of property and flavor:It is bitter, sweet, it is cold in nature;Return lung, Liver Channel.
Effect:Effect:Dispelling wind and heat from the body, clear liver and improve vision.Cure mainly:For syndrome of superficies attacked by wind-heat, warm disease from the beginning of, cough caused by dryness-heat, Red eye, swell pain, mesh are secretly dim-sighted etc..
Peanut leaf
Meridian distribution of property and flavor:Property is sweet light;Taste is put down;Return liver warp.
Major function:It is clearing heat and detoxicating, decompression of allaying excitement.Main traumatic injury, carbuncle sore tumefacting virus, insomnia, hypertension.
Magnetite
Meridian distribution of property and flavor:
Taste is salty, cold in nature;Return liver, the heart, kidney channel.
Effect:Effect tranquillizing the mind by relieving convulsion, calming the liver, hearing-improing and eyesight improving, gas of receiving are relievingd asthma.Cure mainly:For insomnia of palpitating with fear, head Dizzy dizzy, blurring of vision, Hiccough and deaf, kidney deficiency asthma.
Lotus seeds
Meridian distribution of property and flavor:It is sweet, puckery, it is mild-natured;Returns spleen, kidney, the heart channel of Hang-Shaoyin.
Effect:Effect:Tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization.Cure mainly:Cure mainly insufficiency of the spleen chronic diarrhea, protracted dysentery, kidney deficiency Seminal emission, lingering diarrhea, urinary incontinence, under uterine bleeding band, have no peace of mind, shock palpitation not sleep.
Durian
Meridian distribution of property and flavor:It is pungent, sweet, heat.Enter liver, kidney, lung three pass through.
Effect, enriching yin is strong, wind and heat dispersing, normalizing gallbladder to cure jaundice, desinsection are antipruritic, mend body.
Cure mainly, available for diseases such as blood and essence asthenia poliosis, agings.Available for diseases such as wind-heat.Yellow River harnessing subcutaneous ulcer can be used.Can be with controlling The diseases such as mange, pruitus.
The Radix Astragali
Meridian distribution of property and flavor:It is sweet, slightly warm in nature;Returns spleen, lung channel.
Effect:1. tonifying Qi and lifting yang, with the sinking of qi of middle-jiao is controlled, often it is equal with ginseng, the bighead atractylodes rhizome, rattletop, radix bupleuri and uses;It is big in the heart Gas sink, often with radix bupleuri, rattletop, balloonflower root with use.2. invigorating qi for consolidating superficies, the spontaneous perspiration not solid with the deficiency of vital energy is controlled, often with oyster, light wheat, Radix ephedrae is equally used;Instability of surface, susceptible exopathogen person, often with the compatibility such as the bighead atractylodes rhizome, windproof.3. QI invigorating Li Shui, with controlling deficiency of vital energy oedema, Often equally used with the bighead atractylodes rhizome, dried orange peel, Poria cocos.4. nourishing qi to stop, with controlling Qi dysfunction in blood control hematemesis, uterine bleeding, have blood in stool, purpura, Chang Yuren Ginseng, the bighead atractylodes rhizome are equally used.5. qi and activate blood circulation, the numbness caused by qi deficiency to blood stasis is controlled is meciless, often matches somebody with somebody with peach kernel, Radix Angelicae Sinensis, Ligusticum wallichii etc. 5;Hemiplegia, often equally used with earthworm, safflower, Ligusticum wallichii;Chest impediment and cardialgia, often it is equal with the red sage root, Fructus Trichosanthis shell and uses.6. eliminating toxic is arranged Purulence, with insufficiency of vital energy and blood is controlled, purulence is often equal with Radix Angelicae Sinensis, Ligusticum wallichii, pangolin, spina gleditsiae and used into the person that do not burst;Sore is not received long after bursting Mouthful, often it is equal with the root of herbaceous peony, the red sage root, root of Chinese trichosanthes and uses.
Pseudo-ginseng
Meridian distribution of property and flavor:Acrid flavour, sweet, micro-puckery, slight bitter are warm-natured;Return liver, the heart, stomach.
Effect:Effect:Hemostasis, it is promoting blood circulation and removing blood stasis, during blood-activating analgetic hemostasis do not stay the stasis of blood, be adapted to bleeding caused by hemostasis Card.1st, removing blood stasis and hemostasis, demonstrate,proved for various interior external hemorrhages, especially to there is stasis of blood person to be advisable.Pseudo-ginseng can stop blooding, and and can dissipates the stasis of blood, there is hemostasis Without staying the stasis of blood, stagnation resolvation is really blood trouble good medicine without hindering feature just.It is conventional to control hemoptysis, spit blood, have blood in stool, hematuria uterine bleeding and wound Bleeding etc., single, which grinds for oral administration or external application, to prove effective.Also marmor serpentinatum, carbonized hair can be matched somebody with somebody with using, such as《Records of Tradition Chinese and Western Medicine in Combination》 Bleeding-Stopping Bolus.2nd, promoting blood circulation analgesic therapy, for traumatic injury, the stagnant pain of the stasis of blood.Pseudo-ginseng can promoting blood circulation and removing blood stasis and detumescence ding-tong, be traumatology key medicine. Can single is for oral administration or external application, or with blood-activating and qi-moving medicinal with using.Such as so that in hemostasis famous " Yunnan Baiyao " of curing the wound, pseudo-ginseng is main Form medicine.3rd, in recent years with the work(of its stagnation resolvation, with coronary disease and angina pectoris, ischemic cerebrovascular disease, cerebral hemorrhage sequelae etc. is controlled, There is good therapeutic effect.
Cicada slough
Meridian distribution of property and flavor:It is sweet, it is cold in nature;Return lung, Liver Channel.
Effect:Effect:Wind-heat is dissipated, promoting eruption is antipruritic, removing nebula, relieving convulsion and spasm.Cure mainly:For affection of exogenous wind-heat, Warm disease is from the beginning of, measles without adequate eruption, rubella itch, hot eyes, mesh screen, nocturnal fretfulness in infants, lockjaw.
Ant
Meridian distribution of property and flavor:Taste is salty, sour, mild-natured;Return liver warp, kidney channel.
Effect:Effect:Tonifying kidney and benefiting sperm, clearing and activating the channels and collaterals, removing toxicity for detumescence.Cure mainly:Kidney deficiency giddy tinnitus is cured mainly, insomnia is more Dream, impotence and seminal emission, arthralgia pain due to rheumatism, hemiplegia is numb in every limb, erythematosus lupus, chorionitis, dermatomyositis, carbuncle swells furunculosis, poisonous snake Bite.
Safflower
Meridian distribution of property and flavor:Flat property and sweet taste;The thoughts of returning home, Liver Channel.
Major function:It is promoting blood circulation and removing blood stasis to stimulate the menstrual flow, removing pattogenic heat from the blood and toxic material from the body.For:Amenorrhea lump in the abdomen lump in the abdomen, postpartum stasis, febrile virulent maculae, melancholy ruffian Vexed, palpitation with fear is gone mad.
Fructus Corni
Meridian distribution of property and flavor:It is sour, slightly warm in nature;Return liver and kidney channel.
Effect:1. convergence is astringent or styptic treatment for spontaneous sweating, with emission and spermatorrhea, enuresis frequent micturition is controlled, often it is equal with psoralea corylifolia, mantis egg-case and uses;Collapse Leak down blood, menorrhalgia, be often equal with Radix Angelicae Sinensis, the root of herbaceous peony and use;Profuse sweating is collapsed, often with ginseng, monkshood with use.2. tonifying the liver and kidney, use Control kidney deficiency and liver, soreness and weakness of waist and knees, often with prepared rhizome of rehmannia, the bark of eucommia, barrenwort with use.
Radix glycyrrhizae
Meridian distribution of property and flavor:Nature and flavor, it is sweet, it is mild-natured.Channel tropism, the thoughts of returning home, lung, spleen, stomach.
Effect, invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.
Cure mainly, for weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle swells sore Poison, alleviate drug toxicity, strong.
Theory of traditional Chinese medical science thinks:Lung opening at nose, liver opening at eye, kidney opening at ear.That is, by observing face Abnormal conditions, it just will appreciate that the heart, liver, spleen, lung, kidney lesion that may be present.The quality of eyesight depends on catharsis and the battalion of irritability Support.The traditional Chinese medical science says, blood stored in the liver, and blood is the most direct material base of eye activity, so, the prosperity and decline of liver blood can directly influence Visual performance.If deficiency of liver-blood, loss of nutrient of eyes, then bleary-eyed, fuzzy viewing, occur such as the problems such as yctalopia;If Liver Channel fire is contained, It can be seen that furious swelling and pain;The deficiency of the liver-yin, eye paste can be caused dry and astringent, or also show dumb, strabismus of eyeball etc.;Stagnation of liver qi too long, then can Cause bitter taste dizzy.That is eye protection needs first protect liver, and protect liver then wants blood-nourishing, and blood and the five internal organs are closely coupled in theory of traditional Chinese medical science.(1) blood with The heart, blood have trophism, and arteries and veins is the tunnel of blood, and heart is then the power of blood.Heart and blood vessels connect each other, mutually Insertion, works in coordination, the common normal operation for completing blood.Blood, which follows vascular operation, not to stop, so as to by the nutrition in blood Material is constantly transported to whole body, to supply the needs of organism physiology activity.Although blood circulation is the heart and the common work of blood vessels It is dynamic, but heart has been leading, main effect.《Interior warp》Cloud:" the heart controlling the blood vessels of the whole body ", " all blood persons come under the heart ".(2) blood It is also rather close with lung relation with lung blood.The cereal nutrient formed by middle burnt taste sorption enhanced, " it is to turn to above to note in lung arteries and veins to need Blood ", illustrate that lungs also participate in the generation of blood.The traditional Chinese medical science has saying for " convergence of vessels in the lung ", means that all blood vessels of human body can all combine in Lungs, blood are excreted wherein remaining waste by the breathing of lung when flowing through lungs, will further through the effect of lung In fresh air suction body, import in blood.It can be seen that the effect of exhaling the old and inhale the new of lung remains the pure and fresh of blood, fresh blood exists Under the promotion of pectoral qi, then circulation, in blood vessels, temperature supports the vital organs of the human body, four limbs bones of the body collectively.(3) blood is thought with the liver traditional Chinese medical science, blood stored in the liver.Tang Dai Wangbing is explained:" blood stored in the liver, heart row it.The dynamic then blood of people is transported in all warps, and people is quiet, and blood is attributed to liver.WhicheverLiver controlling blood event ." mean, liver has stored blood and adjusts the function of blood volume.When human body is being worked or be excited, body is each Portion needs blood volume to increase, and circulating blood volume also must accordingly increase, and at this moment liver just ejects the blood of storage, for body activities Needs;When people is in rest or stable mood, general activity amount is reduced, and blood volume needed for body is also reduced, and part blood is just store It is stored in liver.If liver is ill, the malfunction of store blood, the normal activity of human body was both influenceed, in terms of also may occur in which blood Lesion.If deficiency of liver-blood (liver blood deficiency), it is impossible to nourish in mesh, then two blurred visions are colored, dry and astringent, yctalopia;It can not moisten and support in muscle, then muscles Arrested anxious, joint stuffiness;The sea of blood can not be filled, then woman in menstrual period amount is few, or even amenorrhoea;If liver dysfunction and liver qi invasion is random, then Store blood is not solid, and easily cause bleeding lesion, and such as spitting blood, bleeding from five sense organs or subcutaneous tissue, woman in menstrual period is excessive or uterine bleeding etc..Liver controlling conveyance and dispersion, and main Tibetan Blood.The operation of blood depends on the promotion of gas.When liver catharsis function is normal, then mechanism of qi bar reaches happy, and blood is also unobstructed with gas row It is without hindrance.If catharsis is too late, stagnation of QI due to depression of the liver, blood stasis can be caused, the card such as chest side of body shouting pain occur.If catharsis too, qi-movement disturbance, is then hidden Blood is not consolidated and the lesion that causes bleeding.(4) blood and spleen, the traditional Chinese medical science think, the spleen being the foundation of acquired constitution, and energy Na Gu is bullied, the precise and tiny of paddy of fetching water Metaplasia is blood.The generation of blood and the relation of spleen are the closest.Spleen not only has close relationship, and spleen energy with haematopoiesis System blood.So-called system blood, refer to spleen have have under one's command blood in vascular normal operation and do not spill over the function outside arteries and veins.The doctor of China's early stage Learn works《Hardly possible warp》Point out:" spleen wraps up in blood, warm the five internal organs ", the meaning wrapped up in is exactly to have under one's command.And the system blood function of spleen, the work of complete bad temper With.Qing Dynasty Shen Munan is said:" blood of the vital organs of the human body, temper is relied to have under one's command entirely." later Tang Rong rivers also say:" through cloud The spleen governs the blood, the fortune of blood Row up and down, relies in spleen, insufficiency of the spleen-yang, then can not unite blood entirely ", " life of the person, always with gas system blood ".It can be seen that the operation of blood, is removed Promotion dependent on heart, outside the regulation of liver, it is necessary to have having under one's command for spleen.The prestige of Ming Dynasty's force《Synopsis of Treating Women's Diseases》Say:" blood Spleen is born in, therefore says The spleen governs the blood." illustrate the effect of having under one's command of spleen, it is that source of generating QI and blood has substantial connection with spleen.(5) blood and kidney, The traditional Chinese medical science thinks that kidney storing essence, essence gives birth to marrow, medullization blood.Meanwhile in kidney the gate of vitality be Primordial Qi direct bearing, 12 through root, the source of vital function, And the place of motive power that is warm, promoting blood biochemical.It can be seen that kidney is to form one of main organs of blood, therefore the traditional Chinese medical science has The saying of " green blood is kidney at all ".And the elite of blood can turn to kidney essense.Such as Sui Dynasty Chao Yuanfang (550-630 A.D.)《The General Treatise on the Cause and Symptoms of Diseases》Say:" kidney Store essential substances, the institute of smart person's blood into ".Qing Dynasty Tang Rong is said in river:" kidney storing essence, though it is so smart based on kidney, and close the institute of painstaking effort ".The meaning It is to say, essence and blood sharing the same origin can mutual inversion of phases.Therefore, normal essence and blood and mended in treatment.Such as alpastic anemia, invigorating the spleen is used Kidney-Nourishing tends to obtain preferable hematopoiesis.Equally, deficiency of kidney-essence person also gives to fill blood it while with kidney-reinforcing drug Product, help production of sperm mends marrow.
The beneficial effects of the invention are as follows:
The eye sticker of the present invention controls illness in eye and magnetotherapy is combined with Chinese medicine, traditional Chinese medicinal components from protect liver, strong kidney, invigorating the spleen and stomach, Nourishing heart is set out, and alleviates kopiopia, treatment myopia.Coordination sight, the medication of the Overall View side of sending of the integrated use traditional Chinese medical science, transfer the work of the five internal organs Property, the abundant of blood supply is ensured with the vigor of the five internal organs, then the nutritional sufficiency of liver, ensure that the vigor of eye is sufficient, that is, coordinated Reach therapeutic effect on the basis of body whole body function, meanwhile, by heating and magnetotherapy effect, drug effect is preferably reached eye Everywhere, more effectively reach and alleviate kopiopia, the purpose for the treatment of myopia.
In the formula of Chinese medicine composition, peppermint head clearing, relieving sore-throat, promoting eruption, black rice appetizing benefit in, invigorating the spleen promoting blood circulation, improving eyesight, The multi minerals such as the protein, manganese, zinc of human body needs money is supplemented simultaneously;Rhizome of chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, borneol lead to all keys, Stagnated fire is dissipated, goes screen improving eyesight, swelling and pain relieving, Paper mulberry Fruit kidney tonifying clearing liver, improving eyesight, diuresis is monarch drug in a prescription altogether;Leatherleaf mahonia heat-clearing and damp-drying drug, purging intense heat Removing toxic substances, crowtoe qi-restoratives;Heat-clearing;Quench the thirst;, the fruit of Chinese wolfberry is nourishing liver and kidney, benefiting shrewd head, cassia seed heat-clearing improving eyesight, control irascibility, gold and silver Spend clearing heat and detoxicating, the moon is held back in root of herbaceous peony blood-nourishing, soft liver analgesic, suppressing liver-YANG, mulberry leaf dispelling wind and heat from the body, is clear liver and improved vision, peanut leaf heat-clearing solution Poison, decompression of allaying excitement, lotus seeds tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization are ministerial drug altogether;Durian enriching yin is strong, wind and heat dispersing, cholagogic Removing jaundice, Radix Astragali tonifying Qi and lifting yang, invigorating qi for consolidating superficies, QI invigorating Li Shui, nourishing qi to stop, qi and activate blood circulation, pseudo-ginseng blood-circulation-invigovating stagnation resolvation, during blood-activating analgetic The stasis of blood, cicada slough removing nebula are not stayed in hemostasis, and relieving convulsion and spasm, magnetite is calming the liver, hearing-improing and eyesight improving, ant tonifying kidney and benefiting sperm, clearing and activating the channels and collaterals, Removing toxicity for detumescence;Safflower is promoting blood circulation and removing blood stasis to stimulate the menstrual flow, removing pattogenic heat from the blood and toxic material from the body, and it is adjutant altogether that Fructus Corni, which tonifies the liver and kidney,;With the monarch and his subjects of uniqueness in side Assistant makes theoretical direction medication, monarch drug in a prescription plan as a whole sharp mesh, tonify the liver and kidney, clearing lung-heat, strengthening the spleen and stomach, blood-activating and qi-promoting the effect of;Ministerial drug matrimony vine Son is nourishing liver and kidney, and the moon, soft liver analgesic are held back in benefiting shrewd head, root of herbaceous peony blood-nourishing, and suppressing liver-YANG, cassia seed controls irascibility, honeysuckle heat-clearing solution Malicious common coordination liver function, PFT;Peanut leaf is allayed excitement decompression, lotus seeds tonifying spleen, the deficiency of mental-tranquilization gain monarch drug in a prescription heart function; Adjutant durian enriching yin is strong, Radix Astragali tonifying Qi and lifting yang, pseudo-ginseng blood-circulation-invigovating stagnation resolvation, safflower is promoting blood circulation and removing blood stasis stimulates the menstrual flow, and removing pattogenic heat from the blood and toxic material from the body, cicada slough are bright Mesh moves back that screen, magnetite are calming the liver, and hearing-improing and eyesight improving, ant tonifying kidney and benefiting sperm, clearing and activating the channels and collaterals, Fructus Corni tonifies the liver and kidney, to tonify the liver and kidney, The comprehensive concord monarch drug in a prescription of promoting blood circulation and removing obstruction in channels, tonifying Qi and lifting yang, removing nebula, the function of ministerial drug, are invigorated the spleen and benefited qi with radix glycyrrhizae, clearing heat and detoxicating, Expelling phlegm and arresting coughing, clearing profit lung, relieving spasm to stop pain, coordinating the drug actions of a prescription;Then blood vessels are unimpeded for XINANNING, and then blood vessels must support lung clearly, and liver function is strong Then store blood foot, binocular can be nourished, and spleen can unite blood, kidney storing essence, and the institute of smart person's blood with strengthening spleen, tonifying kidney method into tending to take Preferable hematopoiesis is obtained, the five internal organs unobstructed vessel, visual problems are inherently derived solution, while are induced with magnetite, and Chinese medicine is effective Composition imports eye acupuncture point, gain therapeutic effect.
The preparation method of Chinese medicine composition provided by the invention, organically combined with supercritical extract, microwave and refluxing extraction, On the basis of each bulk drug pharmaceutical properties in considering inventive formulation, the characteristics of making full use of different extraction processes, more For efficient effective component extracting.
Brief description of the drawings
The structural representation of Fig. 1 eye stickers of the present invention;
Fig. 2 paste eye bit architecture schematic diagram.
Embodiment
Embodiment 1
It is a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, including patch eye position 1 and positioned at patch eye The symmetrically arranged fixed side arm 2 in 1 both sides of position, the patch eye position 1 by bonding the zone of heating 11 of connection with successively from outside to inside Drug composition layer 12 and nonwoven gauze 13 form, and the surrounding of patch eye position 1 is provided with contact 14, and small magnetic is fixed with contact 14 Iron;The end of the volume of fixed side arm 2 is provided with the magnetic clasp 21 being mutually matched;
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 85% Chinese medical extract, 15% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 3% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 100 parts of peppermint, 100 parts of black rice, 100 parts of rhizome of chuanxiong, borneol 100 parts, it is 100 parts of Paper mulberry Fruit, 100 parts of leatherleaf mahonia, 80 parts of crowtoe, 80 parts of the fruit of Chinese wolfberry, 80 parts of cassia seed, 80 parts of honeysuckle, white 80 parts of Chinese herbaceous peony;60 parts of mulberry leaf, 60 parts of peanut leaf, 60 parts of magnetite, 60 parts of magnetite, 30 parts of durian, 30 parts of the Radix Astragali, 30 parts of pseudo-ginseng, cicada slough 30 parts;30 parts of ant;10 parts of 30 parts of safflower, 30 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer, comprises the following steps,
S1:By the peppermint, rhizome of chuanxiong, the Radix Astragali and borneol, Ultramicro-powder, CO are crushed2Supercritical extract, entrainment is used as using ethanol Agent, extract are concentrated and dried, are standby;Extracting pressure:25Mpa, concentration of alcohol 95%, solid-to-liquid ratio:5-5.5:1, extraction temperature is 500C, extraction time are that 4h rate of flow of fluids are 35kg/h;
S2:The black rice, mulberry leaf, peanut leaf and durian are crushed, add volume fraction 35-45% ethanol water, 35 DEG C of ultrasonic extraction 30-40min, power 1000W, extract are concentrated and dried, are standby;
S3:By the fruit of Chinese wolfberry, cassia seed, honeysuckle, the root of herbaceous peony, safflower, Fructus Corni, Paper mulberry Fruit, leatherleaf mahonia, crowtoe With radix glycyrrhizae crush, immersion, add 2 times of parts by weight the ethanol of volume parts 75% immersion, refluxing extraction 20 minutes, separation fraction and Filter residue;Filter residue is added to the clear water of 2 times of parts by weight, and instills the acetic acid that volume fraction is 1%, stirring, immersion, refluxing extraction 20 Minute, phegma is reclaimed, is merged, concentration, drying for standby.Refluxing extraction, phegma is reclaimed, merged, concentration, drying for standby;
S4:The cicada slough, ant, pseudo-ginseng and lotus seeds are baked, crushed into powder shape;
S5:S1, S2, S3 and S4 products therefrom are mixed, add transdermal penetration agent, magnetite is uniformly applied in polyurethane film Portion, and the barrier paper gluing that shape size and polyurethane film are matched is thereon, both.
Embodiment 2
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 95% Chinese medical extract, 5% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 5% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 150 parts of peppermint, 120 parts of black rice, 120 parts of rhizome of chuanxiong, borneol 120 parts, 120 parts of Paper mulberry Fruit, 120 parts of leatherleaf mahonia, 100 parts of crowtoe, 100 parts of the fruit of Chinese wolfberry, 100 parts of cassia seed, honeysuckle 100 Part, 100 parts of the root of herbaceous peony;80 parts of mulberry leaf, 80 parts of peanut leaf, 80 parts of magnetite, 80 parts of lotus seeds, 50 parts of durian, 50 parts of the Radix Astragali, pseudo-ginseng 50 Part, 50 parts of cicada slough;50 parts of ant;15 parts of 50 parts of safflower, 50 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer, comprises the following steps,
S1:By the peppermint, rhizome of chuanxiong, the Radix Astragali and borneol, Ultramicro-powder, CO are crushed2Supercritical extract, entrainment is used as using ethanol Agent, extract are concentrated and dried, are standby;Extracting pressure:30Mpa, concentration of alcohol 95%, solid-to-liquid ratio:5.5:1, extraction temperature is 500C, extraction time are that 4h rate of flow of fluids are 35kg/h;
S2:The black rice, mulberry leaf, peanut leaf and durian are crushed, the ethanol water of addition volume fraction 45%, 45 DEG C Ultrasonic extraction 40min, power 2000W, extract are concentrated and dried, are standby;
S3:By the fruit of Chinese wolfberry, cassia seed, honeysuckle, the root of herbaceous peony, safflower, Fructus Corni, Paper mulberry Fruit, leatherleaf mahonia, crowtoe Crushed with radix glycyrrhizae, immersion, add the volume parts 75-85% ethanol immersion of 2-3 times of parts by weight, refluxing extraction 20-30 minutes, divide From fraction and filter residue;Filter residue is added to the clear water of 2-3 times of parts by weight, and instills the acetic acid that volume fraction is 1%, stirring, immersion, Refluxing extraction 20-30 minutes, phegma is reclaimed, merged, concentration, drying for standby;
S4:The cicada slough, ant, pseudo-ginseng and lotus seeds are baked, crushed into powder shape;
S5:S1, S2, S3 and S4 products therefrom are mixed, add transdermal penetration agent, magnetite is uniformly applied in polyurethane film Portion, and the barrier paper gluing that shape size and polyurethane film are matched is thereon, both.
Embodiment 3
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 90% Chinese medical extract, 10% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 4% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 125 parts of peppermint, 110 parts of black rice, 110 parts of rhizome of chuanxiong, borneol 110 parts, it is 110 parts of Paper mulberry Fruit, 110 parts of leatherleaf mahonia, 90 parts of crowtoe, 90 parts of the fruit of Chinese wolfberry, 90 parts of cassia seed, 90 parts of honeysuckle, white 90 parts of Chinese herbaceous peony;70 parts of mulberry leaf, 70 parts of peanut leaf, 70 parts of magnetite, 70 parts of lotus seeds, 40 parts of durian, 40 parts of the Radix Astragali, 40 parts of pseudo-ginseng, cicada slough 40 parts;40 parts of ant;15 parts of 40 parts of safflower, 40 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer, comprises the following steps,
S1:By the peppermint, rhizome of chuanxiong, the Radix Astragali and borneol, Ultramicro-powder, CO are crushed2Supercritical extract, entrainment is used as using ethanol Agent, extract are concentrated and dried, are standby;Extracting pressure:28Mpa, concentration of alcohol 95%, solid-to-liquid ratio:5.3:1, extraction temperature is 500C, extraction time are that 4h rate of flow of fluids are 35kg/h;
S2:The black rice, mulberry leaf, peanut leaf and durian are crushed, the ethanol water of addition volume fraction 40%, 40 DEG C Ultrasonic extraction 35min, power 1500W, extract are concentrated and dried, are standby;
S3:By the fruit of Chinese wolfberry, cassia seed, honeysuckle, the root of herbaceous peony, safflower, Fructus Corni, Paper mulberry Fruit, leatherleaf mahonia, crowtoe Crushed with radix glycyrrhizae, immersion, add the ethanol of volume parts 80% immersion of 2.5 times of parts by weight, refluxing extraction 25 minutes, separate fraction And filter residue;Filter residue is added to the clear water of 2.5 times of parts by weight, and instills the acetic acid that volume fraction is 1%, stirring, immersion, backflow carry Take 25 minutes, reclaim phegma, merge, concentration, drying for standby;
S4:The cicada slough, ant, pseudo-ginseng and lotus seeds are baked, crushed into powder shape;
S5:S1, S2, S3 and S4 products therefrom are mixed, add transdermal penetration agent, magnetite is uniformly applied in polyurethane film Portion, and the barrier paper gluing that shape size and polyurethane film are matched is thereon, both.
Embodiment 4
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 86% Chinese medical extract, 14% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 3% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 120 parts of peppermint, 105 parts of black rice, 105 parts of rhizome of chuanxiong, borneol 105 parts, it is 105 parts of Paper mulberry Fruit, 105 parts of leatherleaf mahonia, 85 parts of crowtoe, 85 parts of the fruit of Chinese wolfberry, 85 parts of cassia seed, 85 parts of honeysuckle, white 85 parts of Chinese herbaceous peony;65 parts of mulberry leaf, 65 parts of peanut leaf, 65 parts of magnetite, 65 parts of lotus seeds, 35 parts of durian, 35 parts of the Radix Astragali, 35 parts of pseudo-ginseng, cicada slough 12 parts of 35 parts, 35 parts of ant, 35 parts of safflower, 35 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer is shown in embodiment 3.
Embodiment 5
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 88% Chinese medical extract, 12% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 5% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 130 parts of peppermint, 115 parts of black rice, 115 parts of rhizome of chuanxiong, borneol 115 parts, it is 115 parts of Paper mulberry Fruit, 115 parts of leatherleaf mahonia, 95 parts of crowtoe, 95 parts of the fruit of Chinese wolfberry, 95 parts of cassia seed, 95 parts of honeysuckle, white 95 parts of Chinese herbaceous peony;75 parts of mulberry leaf, 75 parts of peanut leaf, 75 parts of magnetite, 75 parts of lotus seeds, 45 parts of durian, 45 parts of the Radix Astragali, 45 parts of pseudo-ginseng, cicada slough 45 parts;45 parts of ant;15 parts of 45 parts of safflower, 45 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer is shown in embodiment 3.
Embodiment 6
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 92% Chinese medical extract, 8% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 3-5% Laurocaprams;
The composition and its parts by weight of the Chinese medicine material are as follows, 126 parts of peppermint, 112 parts of black rice, 108 parts of rhizome of chuanxiong, borneol 111 parts, it is 114 parts of Paper mulberry Fruit, 113 parts of leatherleaf mahonia, 88 parts of crowtoe, 86 parts of the fruit of Chinese wolfberry, 94 parts of cassia seed, 87 parts of honeysuckle, white 93 parts of Chinese herbaceous peony;66 parts of mulberry leaf, 73 parts of peanut leaf, 72 parts of magnetite, 71 parts of lotus seeds, 42 parts of durian, 36 parts of the Radix Astragali, 37 parts of pseudo-ginseng, cicada slough 38 parts;39 parts of ant;13 parts of 41 parts of safflower, 42 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer is shown in embodiment 3.
Embodiment 7
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 89% Chinese medical extract, 11% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 5% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 101 parts of peppermint, 102 parts of black rice, 103 parts of rhizome of chuanxiong, borneol 118 parts, it is 117 parts of Paper mulberry Fruit, 116 parts of leatherleaf mahonia, 82 parts of crowtoe, 98 parts of the fruit of Chinese wolfberry, 96 parts of cassia seed, 99 parts of honeysuckle, white 97 parts of Chinese herbaceous peony, 61 parts of mulberry leaf, 63 parts of peanut leaf, 78 parts of magnetite, 76 parts of lotus seeds, 31 parts of durian, 32 parts of the Radix Astragali, 33 parts of pseudo-ginseng, cicada slough 48 parts;47 parts of ant;11 parts of 46 parts of safflower, 49 parts of Fructus Corni and radix glycyrrhizae.
The preparation method embodiment 3 of the Chinese traditional medicine composition nitride layer.
Embodiment 8
A kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, its structure is substantially the same manner as Example 1, Its difference is,
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 94% Chinese medical extract, 6% transdermal enhancer; The transdermal enhancer is the ethanol solution that mass fraction is 5% Laurocapram;
The composition and its parts by weight of the Chinese medicine material are as follows, 148 parts of peppermint, 101 parts of black rice, 118 parts of rhizome of chuanxiong, borneol 100 parts, it is 120 parts of Paper mulberry Fruit, 104 parts of leatherleaf mahonia, 81 parts of crowtoe, 82 parts of the fruit of Chinese wolfberry, 83 parts of cassia seed, 84 parts of honeysuckle, white 95 parts of Chinese herbaceous peony;62 parts of mulberry leaf, 65 parts of peanut leaf, 70 parts of magnetite, 72 parts of lotus seeds, 35 parts of durian, 45 parts of the Radix Astragali, 38 parts of pseudo-ginseng, cicada slough 44 parts;30 parts of ant;13 parts of 50 parts of safflower, 40 parts of Fructus Corni and radix glycyrrhizae.
The preparation method of the Chinese traditional medicine composition nitride layer is shown in embodiment 3.
Comparative example 1
Comparative example 1 is substantially the same manner as Example 3, and its difference is, deletes ant component.
Comparative example 2
Comparative example 2 is substantially the same manner as Example 3, and its difference is, by black rice with etc. the black soya beans of parts by weight substitute.
Black soya bean:
Meridian distribution of property and flavor:Sweet, cold nature is mild-natured, enter spleen, kidney channel.
Effect:Effect:Kidney tonifying benefit is cloudy, invigorating spleen to remove dampness, except thermal detoxification.Cure mainly blindness, screen film.
Comparative example 3
Comparative example 3 is substantially the same manner as Example 3, and its difference is, 40 parts of increase traditional Chinese medicinal components Radix Angelicae Sinensis.
Radix Angelicae Sinensis
Meridian distribution of property and flavor:Radix Angelicae Sinensis is sweet, pungent, warm-natured;Return liver warp, the heart channel of Hang-Shaoyin, the spleen channel.
Effect:1. tonifying blood and regulating menstruation, pale complexion, irregular menstruation etc. caused by the deficiency of blood is controlled, often with prepared rhizome of rehmannia, the Radix Astragali, The root of herbaceous peony equally with 2. promoting blood circulation and stopping pain, with traumatic injury is controlled, blood stasis and swelling pain, is often equal with frankincense, myrrh, peach kernel and used;Cold stagnant channels and collaterals Numbness pain, be often equal with Ligusticum wallichii, cassia twig, asarum and use.3. relax bowel, the dry constipation of intestines caused by blood deficiency and depleted fluid is controlled, often with meat desert Rong, brush-cherry seed, Fructus Aurantii are the same as use.
Comparative example 4
Comparative example 4 is substantially the same manner as Example 3, and its difference is, the parts by weight of peppermint component are changed into 70 parts.
Comparative example 5
Comparative example 5 is substantially the same manner as Example 3, and its difference is, deletes trace element.
Comparative example 6
Comparative example 6 is substantially the same manner as Example 3, and its difference is, deletes vitamin.
Comparative example 7
Comparative example 7 is substantially the same manner as Example 3, and its difference is, deletes sodium carboxymethylcellulose.
Comparative example 8
Comparative example 8 is substantially the same manner as Example 3, and its difference is, in preparation method step, deletes acetic acid.
Clinical trial
1st, clinical case:Treatment group 166,320, man 84, female 82, age 17-68 year, left eye 6, right eye 6 Example, remaining is eyes patient:Control group 182,360, man 85, female 97, age 18-66 year, right eye 2, left eye 2 Example, remaining is eyes patient.
2nd, using treatment method and experimental method:
Application method:Heating position is first opened before sticking and completes heating, then circumference of eyes is close in contact, passes through magnetic clasp Eye sticker is fixed.
Experimental method:Eye sticker obtained by embodiment 1-8 is affixed on eye, 3-4 times on the one, a 10-15 minute;When eyesight reaches Time or number are reduced to that can be considered when more than 1.0, course for the treatment of 30 days.Control group:Control group 1 is drop ZHENSHIMING DIYANYE, Usage:It is daily 4-6 times, each 1-2 drops, the course for the treatment of 30 days.Control group 2-9 is the method by embodiment group, sticks comparative example 1-8 institutes Eye sticker, 3-4 times on the one, a 10-15 minute;Reduction can be considered when eyesight reaches more than 1.0, course for the treatment of 30 days.
3rd, clinical treatment outcome
1) curative effect determinate standard
Cure:It can adhere to reading or watch attentively fine work more than 1 hour, eye conditions and constitutional symptom disappearance person.
It is effective:It can adhere to reading or watch attentively fine work 30-60 minutes that (transience hypopsia person, severe are closed mesh and stopped Breath vision restoration after 10 minutes, slight and moderate disease are lost), eye symptom and constitutional symptom respectively have 2 persons of being obviously improved.
Effectively:Read or watch attentively before fine work is relatively treated and extend more than 10 minutes (transience hypopsia person, severes Vision restoration after mesh is rested 20 minutes is closed, severe closes vision restoration after mesh is rested 10 minutes, and slight disease is lost), eye symptom and complete Body symptom respectively has 2 persons of being obviously improved.Or respectively there is the person of being obviously improved.
It is invalid:Pretherapy and post-treatment eye symptom and constitutional symptom are without improver.
(2) treatment results
Treatment group 320, effective 320, effective percentage 100%;Control group 360, it is effective 295, efficient 81.94%.Individual difference between two groups can be ignored.It the results are shown in Table 1.
The treatment group of table 1 and control group curative effect statistical analysis
(3) model case:
Zhang, man, 16 years old, Henan high school student, just blurred vision, One's spirits are drooping, notice did not collected in September, 2010 In, easily feel sleepy, start to take medicine of the present invention in by the end of August, 2010, using eye sticker of the present invention, notice is concentrated two days later, essence God improves, and continues to take two days, memory, vision restoration, is discontinued, does not recur so far.
Liu, female, 40 years old, people from Hefei ,Anhui, co-director, operating pressure was big, and start to lose face distending pain and eye for 2011 Portion is congested, is not treated, neck shoulder aching pain in waist and back symptom then occurs, start to take Chinese medicine of the present invention therewith, two days later symptom Disappear, mental restoration, continue to be discontinued after taking 4 days.
Lin, female, 30 years old, Zhengzhou, henan people, it is engaged in paperwork for many years, starts within 2012 to occur that eyes are dry and astringent, fear The situations such as light stream tear, blurred vision, eye distending pain, sometimes also with headache, nausea, with taking Chinese medicine of the present invention, after 1 day, Eyes are dry and astringent, symptom of shedding tears disappears, and continue to be discontinued after taking 3 days, do not recur so far.
Pass through above-mentioned clinical trial, it can be seen that also have fatigue-relieving effect, and no to twenty-twenty eyes What is adversely affected.
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, this area is common Other modifications or equivalent substitution that technical staff is made to technical scheme, without departing from technical solution of the present invention Spirit and scope, all should cover among scope of the presently claimed invention.

Claims (7)

1. a kind of alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia, it is characterised in that including patch eye position(1) With positioned at patch eye position(1)The symmetrically arranged fixed side arm in both sides(2), the patch eye position(1)By bonding connection from outside to inside Zone of heating(11)With Chinese traditional medicine composition nitride layer(12)And nonwoven gauze(13)Composition, patch eye position(1)Surrounding be provided with contact (14), contact(14)On be fixed with small magnet;The fixed side arm(2)End be provided with the magnetic clasp being mutually matched(21);
The Chinese traditional medicine composition nitride layer is made up of the raw material of following parts by weight, 85-95% Chinese medical extracts, 5-15% transdermal enhancers;
The composition and its parts by weight of the raw material of the Chinese medicine composition are as follows, peppermint 100-150 parts, black rice 100-120 parts, river Vault 100-120 parts, borneol 100-120 parts, Paper mulberry Fruit 100-120 parts, leatherleaf mahonia 100-120 parts, crowtoe 80-100 parts, Chinese holly Matrimony vine 80-100 parts, cassia seed 80-100 parts, honeysuckle 80-100 parts, root of herbaceous peony 80-100 parts, mulberry leaf 60-80 parts, peanut leaf 60- 80 parts, magnetite 60-80 parts, lotus seeds 60-80 parts, durian 30-50 parts, Radix Astragali 30-50 parts, pseudo-ginseng 30-50 parts, cicada slough 30-50 parts, Ant 30-50 parts, safflower 30-50 parts, Fructus Corni 30-50 parts and radix glycyrrhizae 10-15 parts.
2. eye sticker according to claim 1, it is characterised in that the composition and its parts by weight of the Chinese medicine material are as follows, Peppermint 120-130 parts, black rice 105-115 parts, rhizome of chuanxiong 105-115 parts, borneol 105-115 parts, Paper mulberry Fruit 105-115 parts, contribution Wooden 105-115 parts, crowtoe 85-95 parts, fruit of Chinese wolfberry 85-95 parts, cassia seed 85-95 parts, honeysuckle 85-95 parts, root of herbaceous peony 85- 95 parts, mulberry leaf 65-75 parts, peanut leaf 65-75 parts, magnetite 65-75 parts, lotus seeds 65-75 parts, durian 35-45 parts, Radix Astragali 35-45 Part, pseudo-ginseng 35-45 parts, cicada slough 35-45 parts, ant 35-45 parts, safflower 35-45 parts, Fructus Corni 35-45 parts and radix glycyrrhizae 12-15 Part.
3. eye sticker according to claim 1, it is characterised in that the composition and its parts by weight of the Chinese medicine material are as follows, 125 parts of peppermint, 110 parts of black rice, 110 parts of rhizome of chuanxiong, 110 parts of borneol, 110 parts of Paper mulberry Fruit, 110 parts of leatherleaf mahonia, 90 parts of crowtoe, Chinese holly 90 parts of matrimony vine, 90 parts of cassia seed, 90 parts of honeysuckle, 90 parts of the root of herbaceous peony, 70 parts of mulberry leaf, 70 parts of peanut leaf, 70 parts of magnetite, lotus seeds 70 Part, 40 parts of durian, 40 parts of the Radix Astragali, 40 parts of pseudo-ginseng, 40 parts of cicada slough, 40 parts of ant, 40 parts of safflower, 40 parts of Fructus Corni and radix glycyrrhizae 15 Part.
4. according to the eye sticker described in claim any one of 1-3, it is characterised in that the transdermal enhancer is that mass fraction is 3- The ethanol solution of 5% Laurocapram.
5. eye sticker according to claim 4, it is characterised in that the preparation method of the Chinese traditional medicine composition nitride layer, including it is as follows Step,
S1:By the peppermint, rhizome of chuanxiong, the Radix Astragali and borneol, Ultramicro-powder, CO are crushed2Supercritical extract, using ethanol as entrainer, extraction Thing is taken to be concentrated and dried, be standby;
S2:The black rice, mulberry leaf, peanut leaf and durian are crushed, add volume fraction 35-45% ethanol water, 35-45 DEG C ultrasonic extraction 30-40min, power 1000-2000W, extract are concentrated and dried, are standby;
S3:By the fruit of Chinese wolfberry, cassia seed, honeysuckle, the root of herbaceous peony, safflower, Fructus Corni, Paper mulberry Fruit, leatherleaf mahonia, crowtoe and sweet Grass meal is broken, immersion, refluxing extraction, reclaims phegma, merges, concentration, drying for standby;
S4:The cicada slough, ant, pseudo-ginseng and lotus seeds are baked, crushed into powder shape;
S5:S1, S2, S3 and S4 products therefrom are mixed, the agent of addition transdermal penetration, magnetite are uniformly applied in the middle part of polyurethane film, And the barrier paper gluing that shape size and polyurethane film match is thereon, both.
6. eye sticker according to claim 5, it is characterised in that extracting pressure in S1:25-30Mpa, concentration of alcohol 95%, Gu Liquor ratio:5-5.5:1, extraction temperature 500C, extraction time are that 4h rate of flow of fluids are 35kg/h.
7. eye sticker according to claim 5, it is characterised in that the refluxing extraction in S3 particularly, adds 2-3 times of weight The volume parts 75-85% ethanol immersion of part, refluxing extraction 20-30 minutes, separates fraction and filter residue;By filter residue addition, 2-3 times weighs The clear water of part is measured, and instills the acetic acid that volume fraction is 1%, stirring, immersion, refluxing extraction 20-30 minutes, phegma is reclaimed, closes And concentrate, drying for standby.
CN201711048417.5A 2017-10-31 2017-10-31 It is a kind of to alleviate kopiopia, the compound traditional Chinese medicine composite eye sticker for the treatment of myopia Withdrawn CN107789521A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108404052A (en) * 2018-05-09 2018-08-17 杜世东 Prevention myopia, the pharmaceutical composition and the preparation method and application thereof of amblyopia
EP3955945A4 (en) * 2019-04-13 2023-01-11 Azista Industries Pvt Ltd Polyherbal transdermal patch for pain management and its process of preparation
CN116966235A (en) * 2023-09-20 2023-10-31 北京万明维视力科技有限公司 Traditional Chinese medicine eye ointment for treating myopia and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108404052A (en) * 2018-05-09 2018-08-17 杜世东 Prevention myopia, the pharmaceutical composition and the preparation method and application thereof of amblyopia
EP3955945A4 (en) * 2019-04-13 2023-01-11 Azista Industries Pvt Ltd Polyherbal transdermal patch for pain management and its process of preparation
CN116966235A (en) * 2023-09-20 2023-10-31 北京万明维视力科技有限公司 Traditional Chinese medicine eye ointment for treating myopia and preparation method thereof

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