CN106729402A - It is a kind of to treat medicine of encephalatrophy disease and preparation method thereof - Google Patents

It is a kind of to treat medicine of encephalatrophy disease and preparation method thereof Download PDF

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CN106729402A
CN106729402A CN201611222508.1A CN201611222508A CN106729402A CN 106729402 A CN106729402 A CN 106729402A CN 201611222508 A CN201611222508 A CN 201611222508A CN 106729402 A CN106729402 A CN 106729402A
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王勤
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Abstract

Medicine of encephalatrophy disease and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by Poria cocos, prepared rhizome of rehmannia, Fructus Aurantii, the root of bidentate achyranthes, fructus alpiniae oxyphyllae, grass-leaved sweetflag, Radix Glycyrrhizae, polygala, balloonflower root, ginseng, yncaria stem with hooks, fushen etc., medicine of the present invention has calming heart intelligence development, invigorating qi for tranquilization, the function of removing toxic substances relieving restlessness, for controlling encephalatrophy disease state of an illness instant effect, good effect has no side effect.

Description

It is a kind of to treat medicine of encephalatrophy disease and preparation method thereof
Technical field
Medicine of encephalatrophy and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Background technology
Encephalatrophy refers to cause brain tissue that organic disease occurs in itself by a variety of causes and produce a class of atrophy neural Psychotic disorder.Encephalatrophy includes Cerebral Atrophy in Children, adult's encephalatrophy.This disease is multiple to be born in more than 50 years old, and the course of disease is up to the several years To many decades, male is more than women, and encephalatrophy has diffusivity encephalatrophy(Including cortical atrophy, cerebellar atrophy and cortex, cerebellum, Brain stem atrophy)And circumscribed cerebral atrophy(Such as wound, angiosis, encephalic limitation is sexy after being more common in limitation brain organic lesion Dye etc.).Because its cause of disease is complicated, onset is slow, is difficult to be discovered, and the course of disease is long, makes slow progress, and may gradually aggravate, influence The normal life and work of patient.Because Western medicine cannot effectively treat encephalatrophy disease, therefore people to the Chinese medicines of effectively treatment encephalatrophy disease There is great demand in thing, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found effectively control encephalatrophy disease finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science The medicine of the state of an illness, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of the more effective control encephalatrophy disease state of an illness.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection Poria cocos, prepared rhizome of rehmannia, Fructus Aurantii, the root of bidentate achyranthes, fructus alpiniae oxyphyllae, grass-leaved sweetflag, Radix Glycyrrhizae, polygala, balloonflower root, people Ginseng, yncaria stem with hooks, fushen, date, bark of ash, Radix Angelicae Sinensis, the root of herbaceous peony, moutan bark, Chinese yam, Fructus Corni, the fleece-flower root, sealwort, Morinda officinalis, Ligusticum wallichii, Root tuber of aromatic turmeric, Semen Leonuri, the fruit of Chinese magnoliavine, tortoise version, pearl powder, dens draconis bulk drug are combined preparation, and these drug regimens are caused respectively Efficacy of drugs produces synergy such that it is able to effectively treat encephalatrophy disease.Wherein from Poria cocos because its property slightly sweet flavor, puts down, enter The heart, spleen, lung channel, there is an eliminating dampness and diuresis, beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative, control difficult urination oedema distending pain, and phlegm and retained fluid is coughed inverse, vomits The sound of vomiting, diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear is forgetful.From prepared rhizome of rehmannia because its nature and flavor is sweet, tepor enters liver and kidney channel, there is enriching yin, mends The function of blood, it is few to control deficiency of Yin blood, waist knee flaccidity, Cough osteopyrexia, and seminal emission, uterine bleeding, irregular menstruation is quenched one's thirst, number of urinating, deaf, blurred vision. From Fructus Aurantii because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, there is a relieving stagnant Qi, row phlegm, the function of disperse accumulations, it is stagnant to control chest diaphragm phlegm, The feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight, prolapse of the anus, the prolapse of uterus after diarrhea.From the root of bidentate achyranthes because its nature and flavor sweetness and bitterness is sour, It is flat, enter liver and kidney channel, life scattered blood stasis, the function of subduing inflammation controls gonorrhoea, hematuria, Amenorrhea, Disorder lumps in the abdomen, difficult labour, placenta retension, postpartum Control waist and knee ostalgia, spasm of limbs, Impotence numbness are controlled in abdominal pain due to blood stasis, larynx numbness, carbuncle swells, traumatic injury, ripe use filling liver kidney, strengthening the bones and muscles.From benefit Because its nature and flavor is pungent, temperature enters spleen, kidney channel to intelligence benevolence, there is warm spleen, warms up kidney, and solid and gas, the function of puckery essence controls cold air stomachache, and syncope due to pathogenic cold is told Rush down, many salivas, pass out semen, dribbling urination, many nights many urine.From grass-leaved sweetflag because its nature and flavor is arduous, tepor enters the heart, liver, the spleen channel, Have and have one's ideas straightened out, slit phlegm, qi-regulating, promoting blood circulation dissipates wind, the function of drying, Zhi Dian Epilepsy, coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition Unhappiness, stomachache, stomachache, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung Through, have and process, deficiency of food weakness of the spleen and the stomach with controlling with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription, loose stool of suffering from abdominal pain, overstrain heating, Consumptive lung disease is coughed, palpitaition, shies carbuncle, raw with controlling abscess of throat, peptic ulcer, ulcer sores, antidote poison and is poisoned by food.From remote Because its nature and flavor toil, temperature enters the heart, kidney channel to will, there is a tranquilize the mind and promote the intelligence, eliminating the phlegm, the function of Xie Yu, controls palpitation with fear, forgetful, nocturnal emission, Insomnia, cough ant phlegm, ulcer sore swells.From balloonflower root because its nature and flavor toil, puts down, enter lung, stomach, there is out facilitaing lung gas, eliminating the phlegm The function of apocenosis, controls exogenous cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache.From ginseng because its property Sweet micro-sweet, temperature, enters spleen, lung channel, reinforces vital energy, and takes off admittedly and promotes the production of body fluid, the function of calming the nerves, and it is deficient to control internal lesion caused by overexertion, deficiency of food, burnout, instead Stomach tells food, and lingering diarrhea of defecating, empty cough and asthma promotees, and spontaneous perspiration takes off cruelly, and palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, Children are frightened slowly and void is not multiple long, the disease of all qi-blood-body fluid deficiencies.It is cool from yncaria stem with hooks because its is bitter in taste, enter liver, the heart channel of Hang-Shaoyin, There is The flat liver of heat-clearing, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. controls little Jing Epilepsy Chi Zong, and adult's slight Hypertension is dizzy, dizzy, married woman's sub- Epilepsy.From Fushen is put down because its property slightly sweet flavor, enters the heart, the spleen channel, there is calming heart, is calmed the nerves, and the function of Li Shui controls palpitation with fear of having a guilty conscience, forgetful, is lost Dormancy , Jing Epilepsy, difficult urination.From date because its nature and flavor is sweet, temperature enters spleen, stomach, there is tonifying spleen and stomach, and nourishing generate fluid adjusts battalion Defend, the function of antidote poison, control stomach void deficiency of food, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony between ying and wei, palpitation and severe palpitation, hysteria of womam. From bark of ash because its nature and flavor toil, put down, enter liver, stomach, gallbladder channel, there is dispelling wind and eliminating dampness, and a blood relaxing muscles and tendons, the function of reducing fever and causing diuresis, Arthralgia pain due to rheumatism is controlled, muscles and bones contraction, jaundice is had blood in stool, osteopyrexia and fever, children's infantile malnutrition due to digestive disturbances or intestinalparasites heat, difficult urination.From Radix Angelicae Sinensis because its nature and flavor Sweet, acrid, warm, enters the heart, liver, the spleen channel, there is benefiting blood and regulating blood circulation, and menstruction regulating and pain relieving, the function of moisturize laxation controls irregular menstruation, and Amenorrhea is suffered from abdominal pain, Disorder lumps in the abdomen knot gathers, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness is difficult just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.Choosing With the root of herbaceous peony because its nature and flavor picric acid, cool, enter liver, the spleen channel have nourishing blood and liver, analgesic in delaying, and hold back the cloudy function of receiving sweat, control chest and abdomen Pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, under band.From moutan bark because its nature and flavor It is arduous, it is cool, enter the heart, liver and kidney channel, there are heat-clearing, cool blood, and blood, the function of dispersing blood stasis controls heat invading xuefen, sends out spot , Jing Epilepsy, tell, be defeated in battle, Have blood in stool, hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.From Chinese yam because its nature and flavor is sweet, put down, enter lung, spleen, kidney channel, there is strong Spleen, tonifying lung is reinforced the kidney, the function of strengthening the essence, controls splenasthenic diarrhea, and protracted dysentery, cough due to consumptive disease is quenched one's thirst, seminal emission, under band, frequent urination.From Because its nature and flavor is sour, tepor enters liver and kidney channel to Fructus Corni, there is filling liver kidney, puckery vital essence, Gu the function of collapse, controls soreness of waist and knee joint, Dizziness, tinnitus, impotence, seminal emission, frequent urination, liver cold of insufficiency type heat, incessant sweating due to debility, the heart shakes arteries and veins and dissipates.From the fleece-flower root because its property Bitter but sweet flavor is puckery, tepor, enters liver and kidney channel, there is tonifying liver, and kidney-nourishing, blood-nourishing, the function of wind-dispelling controls liver-kidney Yin deficiency, and hair must be early white, the deficiency of blood Dizziness, waist and knee is weak, and muscles and bones is ached, and passes out semen, and collapses band, chronic malaria, protracted dysentery, chronic hepatitis, carbuncle swells, scrofula, intestines wind, haemorrhoids.From Sealwort has a tonifying middle-Jiao and Qi because its property sweet taste, enters spleen, lung, kidney channel, embellish lung, the function of strengthening the bones and muscles, governance wasting fever and chills, Tuberculosis hemoptysis, physically weak deficiency of food after being ill, muscles and bones is weak, rheumatalgia pain, wind favus disease.From Morinda officinalis because its property acrid-sweet flavor, Temperature, enters liver and kidney channel, there is kidney-replenishing, strengthens the bone, the function of wind-damp dispelling, controls impotence, and few abdomen crymodynia, urinary incontinence, uterus void is cold, Wind-cold-dampness arthralgia, soreness of waist and knee joint.From Ligusticum wallichii because its nature and flavor is pungent, temperature, enter liver, gallbladder channel have promote breath and open depression, dispel pathogenic wind and remove dampness, living The function of blood and relieving pain, it is dizzy to control air-cooled headache rotation, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block bitterly, ulcer sore Ulcer.It is cool from root tuber of aromatic turmeric because its nature and flavor is arduous, enter the heart, lung, Liver Channel, there is promoting the circulation of qi solution with the function of cool blood broken stasis of blood controls chest and abdomen The all pains of side of body rib, the mistake heart is demented, pyreticosis coma, spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, women's vicarious menstruation, jaundice.From Semen Leonuri because Its property acrid-sweet flavor, it is cool, enter heart born of the same parents, Liver Channel, there is a promoting blood circulation for regulating menstruation, the function of wind and heat dispersing controls menoxenia, metrorrhagia under band, Postpartum blood stasis are had a pain, liver heat headache, red eye, swell pain, or raw screen film.From the fruit of Chinese magnoliavine because its nature and flavor is sour, temperature enters lung, kidney Through, to astringe the lung, nourshing kidney is promoted the production of body fluid, and receives sweat, and the function of puckery essence is controlled the deficiency syndrome of the lung and breathed with cough, and thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin thin, dream Lose involuntary emission, protracted dysentery and diarrhea.From tortoise version because its nature and flavor is salty sweet, put down, enter liver and kidney channel, there is an enriching yin, checking exuberance of yang, kidney tonifying, strong bone Function, controls the deficiency of the kidney yin, and hectic fever due to yin labor heat is spitted blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, under band, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, long Dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.From pearl because its property sweet-salty, trembles with fear, enter the heart, Liver Channel, there is tranquilizing mind, support The moon relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat-clearing pendant phlegm, goes screen improving eyesight, solves the function of taking poison and growing muscle due, controls palpitation with fear, and palpitation, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, larynx Numbness aphthae in children, mesh life ocular, sore does not close up long.It is cool from dens draconis because its nature and flavor is puckery, enter the heart, Liver Channel, there is tranquillizing the mind by relieving convulsion, The function of relieving restlessness heat, Zhi Jing Epilepsy is demented, and dysphoria with smothery sensation is uneasy, insomnia and dreamful sleep.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount:
It is 8-12 grams of Poria cocos, 8-12 grams of prepared rhizome of rehmannia, 8-12 grams of Fructus Aurantii, 8-12 grams of the root of bidentate achyranthes, 8-12 grams of fructus alpiniae oxyphyllae, 4-8 grams of grass-leaved sweetflag, sweet Careless 4-8 grams, 8-10 grams of polygala, 8-10 grams of balloonflower root, 14-16 grams of ginseng, 8-10 grams of yncaria stem with hooks, 8-10 grams of fushen, 8-10 grams of date, the Qin 8-10 grams of Macrophylla, 8-10 grams of Radix Angelicae Sinensis, 8-10 grams of the root of herbaceous peony, 8-10 grams of moutan bark, 8-10 grams of Chinese yam, 8-10 grams of Fructus Corni, fleece-flower root 8- 10 grams, 8-10 grams of sealwort, 8-12 grams of Morinda officinalis, 8-12 grams of Ligusticum wallichii, 8-12 grams of root tuber of aromatic turmeric, 8-12 grams of Semen Leonuri, 4-6 grams of the fruit of Chinese magnoliavine, 10-20 grams of tortoise version, 10-20 grams of pearl powder, 1-2 grams of dens draconis.
Preferably:
10 grams of Poria cocos, 10 grams of prepared rhizome of rehmannia, 10 grams of Fructus Aurantii, 10 grams of the root of bidentate achyranthes, 10 grams of fructus alpiniae oxyphyllae, 6 grams of grass-leaved sweetflag, 6 grams of Radix Glycyrrhizae, polygala 9 Gram, 9 grams of balloonflower root, 15 grams of ginseng, 9 grams of yncaria stem with hooks, 9 grams of fushen, 9 grams of date, 9 grams of bark of ash, 9 grams of Radix Angelicae Sinensis, 9 grams of the root of herbaceous peony, moutan bark 9 Gram, 9 grams of Chinese yam, 9 grams of Fructus Corni, 9 grams of the fleece-flower root, 9 grams of sealwort, 10 grams of Morinda officinalis, 10 grams of Ligusticum wallichii, 10 grams of root tuber of aromatic turmeric, Semen Leonuri 10 Gram, 5 grams of the fruit of Chinese magnoliavine, tortoise version 15 grams, 15 grams of pearl powder, 1 gram of dens draconis.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Poria cocos:Be soaked in water, clean pull out, it is vexed after, cut into slices, dry;
2nd, prepared rhizome of rehmannia:Take prepared rhizome of rehmannia and put and forge in pot, filling eighty per cant expires, and one pot, two pots of joint yellow mud sealing, upper pressure are covered above Weight, the aobvious coke yellow degree of being of the blank sheet of paper being attached on the lid the bottom of a pan is calcined to mild and heavy respiration, blocks vent, after cooling, is taken out;Or by cultivated land Huang to be put in pot and directly fry charcoal and also may be used;
3rd, Fructus Aurantii:Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried;
4th, the root of bidentate achyranthes:Impurity is picked, is cleaned, softened, go reed, segment is dried;
5th, fructus alpiniae oxyphyllae:Take fructus alpiniae oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take benevolence and smash use to pieces;
6th, grass-leaved sweetflag:Impurity is picked, is cleaned, slightly soaked, run through, cut into slices, dried;
7th, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
8th, polygala:Impurity is picked, segment weeds out grey bits;
9th, balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
10th, ginseng:Except removing LU, segment;
11st, yncaria stem with hooks:Old stalk, impurity are picked, is cleaned, dried;
12nd, Poria cocos:Be soaked in water, clean pull out, it is vexed after, cut into slices, dry;Clear water, slightly vexed profit, plus cinnabar fine powder are drenched, is dispensed Uniformly, and stir at any time, it is degree to stick cinnabar to fushen outside, is then dried, per 100 jin of fushen, with 30 liang of cinnabar;
13rd, date:Net impurity is picked, is dried;
14th, bark of ash:Impurity is picked, except removing LU, is slightly soaked, run through section, dried;
15th, Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried;
16th, the root of herbaceous peony:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, profit is uniform to inside and outside humidity, Section, dries;
17th, moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
18th, Chinese yam:Impurity is picked, capturing bubble to Chinese yam central part with water softens degree of being, pulls out and slightly dries in the air, and section is dried or dried;
19th, Fructus Corni:Clean, except removal core and impurity, dry;
20th, the fleece-flower root:Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, profit is uniform to inside and outside humidity, cuts into slices or the side of being cut into Block, dries;
21st, sealwort:Soil is cleaned, is slightly moistened, cut into slices, dried;
22nd, Morinda officinalis:Impurity is picked, after being soaked with hot water, core is pumped while hot, segment is dried;
23rd, Ligusticum wallichii:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried;
24th, root tuber of aromatic turmeric:It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries;
25th, Semen Leonuri:Complete stool is extracted during fruit maturation, is dried, lay fruit, pick branches and leaves, well sifted impurity;
26th, the fruit of Chinese magnoliavine:Grey bits are weeded out, impurity is removed, is put and steamed in food steamer saturating, taking-up is dried;
27th, tortoise version:Soaked with clear water, scrape off residual meat, cleaned, dried, knock fritter;
28th, pearl powder:Take pearl to clean, wrapped with cloth, boiled altogether about 2 hours with bean curd and water, take out, clean, smash to pieces, add water few Perhaps, superfine powder is ground into, is dried;
29th, dens draconis:Outwash soil, smashes.
2nd, prepare
1st, by the Poria cocos of the weight, prepared rhizome of rehmannia, Fructus Aurantii, the root of bidentate achyranthes, fructus alpiniae oxyphyllae, grass-leaved sweetflag, Radix Glycyrrhizae, polygala, balloonflower root, ginseng, hook Rattan, fushen, date, bark of ash, Radix Angelicae Sinensis, the root of herbaceous peony, moutan bark, Chinese yam, Fructus Corni, the fleece-flower root, sealwort, Morinda officinalis, Ligusticum wallichii, root tuber of aromatic turmeric, Semen Leonuri, the fruit of Chinese magnoliavine, tortoise version, pearl powder, dens draconis medicine are put into decocting container, are added water for the first time 8 times and are measured, and are soaked 60 minutes Afterwards, fry by intense fire to boil and rise, then with being cooked by slow fire 30 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into container It is interior;
2nd, the dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with filtering in 20 minutes is cooked by slow fire, second decoction liquor fallen Enter in container;
3rd, will decoction liquor mixing and stirring twice, obtain final product admixing medical solutions, be divided into 4 doses and take.
Polygala has tranquilize the mind and promote the intelligence in prescription, and the strongly fragrant function of eliminating the phlegm solution is monarch drug in a prescription;Ginseng takes off and promotes the production of body fluid admittedly, invigorating qi for tranquilization, fushen Calming heart, calms the nerves, and both sharp water is ministerial drug, and three taste medicines play calming heart intelligence development, invigorating qi for tranquilization jointly, Gu the de- effect promoted the production of body fluid, treats Encephalatrophy disease effect comprehensively, and based on intelligence promoting and tranquilization, can effective symptom management;Sealwort tonifying middle-Jiao and Qi, embellish lung, strengthening the bones and muscles is assistant Medicine;Pearl tranquilizing mind, to make medicine, all medicines are to take stopgap measures to solution taking poison and growing muscle due with being left.
Medicine of the present invention has calming heart intelligence development, invigorating qi for tranquilization, the function of relieving restlessness of detoxifying, for controlling the encephalatrophy disease state of an illness, the course for the treatment of Short, instant effect, non-relapse after healing, have no toxic side effect.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept encephalatrophy disease out-patient totally 28 for medical treatment.
2nd, diagnostic criteria
The clinical manifestation of encephalatrophy is divided into the major classes of hypophrenia two such as cerebral function decline and dementia, mainly occurs with encephalatrophy Position and degree are relevant.The symptom of encephalatrophy, diffusivity atrophy of cerebral cortex is changed with dementia, hypophrenia, memory disorders, personality Based on change, behavior disorder.Have with hemiplegia and epileptic attack.Localized atrophy is based on personality behavior change;Small encephalatrophy disease Contracting is based on aphasis, limbs incoordination and intentional tremor.Examined according to medical history, symptom, clinical examination and iconography etc. Diagnosed by checking encephalatrophy.
3rd, treatment method
From above-mentioned medicament, taken to patient, 2 times a day, each take 1 dose, early daily, evening respectively takes 1 time, be within 20 days a treatment Journey, continuously takes 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective:Encephalatrophy disease symptom disappears, recovery from illness, and constitution recovers normal;
Take a turn for the better:Encephalatrophy disease symptom is clearly better, and memory has strengthened, and intelligence is progressively recovered;
It is invalid:Improvement standard person is not reached.
5th, treatment results(See the table below)
In above-mentioned treatment, with drug therapy encephalatrophy disease patient 28 of the present invention, as a result effective 14, obvious effective rate is 50%, improvement 10 Example, improvement rate is 35.71%, and invalid 4, total effective rate is 85.71%.

Claims (3)

1. a kind of medicine for treating encephalatrophy disease, it is characterised in that:It is made up of the bulk drug in following amount ranges:
It is 8-12 grams of Poria cocos, 8-12 grams of prepared rhizome of rehmannia, 8-12 grams of Fructus Aurantii, 8-12 grams of the root of bidentate achyranthes, 8-12 grams of fructus alpiniae oxyphyllae, 4-8 grams of grass-leaved sweetflag, sweet Careless 4-8 grams, 8-10 grams of polygala, 8-10 grams of balloonflower root, 14-16 grams of ginseng, 8-10 grams of yncaria stem with hooks, 8-10 grams of fushen, 8-10 grams of date, the Qin 8-10 grams of Macrophylla, 8-10 grams of Radix Angelicae Sinensis, 8-10 grams of the root of herbaceous peony, 8-10 grams of moutan bark, 8-10 grams of Chinese yam, 8-10 grams of Fructus Corni, fleece-flower root 8- 10 grams, 8-10 grams of sealwort, 8-12 grams of Morinda officinalis, 8-12 grams of Ligusticum wallichii, 8-12 grams of root tuber of aromatic turmeric, 8-12 grams of Semen Leonuri, 4-6 grams of the fruit of Chinese magnoliavine, 10-20 grams of tortoise version, 10-20 grams of pearl powder, 1-2 grams of dens draconis.
2. medicine according to claim 1, wherein the consumption of each bulk drug is:
10 grams of Poria cocos, 10 grams of prepared rhizome of rehmannia, 10 grams of Fructus Aurantii, 10 grams of the root of bidentate achyranthes, 10 grams of fructus alpiniae oxyphyllae, 6 grams of grass-leaved sweetflag, 6 grams of Radix Glycyrrhizae, polygala 9 Gram, 9 grams of balloonflower root, 15 grams of ginseng, 9 grams of yncaria stem with hooks, 9 grams of fushen, 9 grams of date, 9 grams of bark of ash, 9 grams of Radix Angelicae Sinensis, 9 grams of the root of herbaceous peony, moutan bark 9 Gram, 9 grams of Chinese yam, 9 grams of Fructus Corni, 9 grams of the fleece-flower root, 9 grams of sealwort, 10 grams of Morinda officinalis, 10 grams of Ligusticum wallichii, 10 grams of root tuber of aromatic turmeric, Semen Leonuri 10 Gram, 5 grams of the fruit of Chinese magnoliavine, tortoise version 15 grams, 15 grams of pearl powder, 1 gram of dens draconis.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Poria cocos:Be soaked in water, clean pull out, it is vexed after, cut into slices, dry;
(2)Prepared rhizome of rehmannia:Take prepared rhizome of rehmannia and put and forge in pot, filling eighty per cant expires, cover one pot above, two pots of joint yellow mud sealing, on Ballast, the aobvious coke yellow degree of being of the blank sheet of paper being attached on the lid the bottom of a pan is calcined to mild and heavy respiration, blocks vent, after cooling, is taken out;Or will be ripe Glutinous rehmannia to be put in pot and directly fry charcoal and also may be used;
(3)Fructus Aurantii:Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried;
(4)The root of bidentate achyranthes:Impurity is picked, is cleaned, softened, go reed, segment is dried;
(5)Fructus alpiniae oxyphyllae:Take fructus alpiniae oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take benevolence and smash use to pieces;
(6)Grass-leaved sweetflag:Impurity is picked, is cleaned, slightly soaked, run through, cut into slices, dried;
(7)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry;
(8)Polygala:Impurity is picked, segment weeds out grey bits;
(9)Balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
(10)Ginseng:Except removing LU, segment;
(11)Yncaria stem with hooks:Old stalk, impurity are picked, is cleaned, dried;
(12)Poria cocos:Be soaked in water, clean pull out, it is vexed after, cut into slices, dry;Clear water, slightly vexed profit, plus cinnabar fine powder are drenched, is dispensed Uniformly, and stir at any time, it is degree to stick cinnabar to fushen outside, is then dried, per 100 jin of fushen, with 30 liang of cinnabar;
(13)Date:Net impurity is picked, is dried;
(14)Bark of ash:Impurity is picked, except removing LU, is slightly soaked, run through section, dried;
(15)Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried;
(16)The root of herbaceous peony:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, profit is uniform to inside and outside humidity, Section, dries;
(17)Moutan bark:Impurity is picked, core is removed, cleaned, run through, cut into slices, dried;
(18)Chinese yam:Impurity is picked, capturing bubble to Chinese yam central part with water softens degree of being, pulls out and slightly dries in the air, and section is dried or dried;
(19)Fructus Corni:Clean, except removal core and impurity, dry;
(20)The fleece-flower root:Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, profit is uniform to inside and outside humidity, cuts into slices or is cut into Square, dries;
(21)Sealwort:Soil is cleaned, is slightly moistened, cut into slices, dried;
(22)Morinda officinalis:Impurity is picked, after being soaked with hot water, core is pumped while hot, segment is dried;
(23)Ligusticum wallichii:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried;
(24)Root tuber of aromatic turmeric:It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries;
(25)Semen Leonuri:Complete stool is extracted during fruit maturation, is dried, lay fruit, pick branches and leaves, well sifted impurity;
(26)The fruit of Chinese magnoliavine:Grey bits are weeded out, impurity is removed, is put and steamed in food steamer saturating, taking-up is dried;
(27)Tortoise version:Soaked with clear water, scrape off residual meat, cleaned, dried, knock fritter;
(28)Pearl powder:Take pearl to clean, wrapped with cloth, boiled altogether about 2 hours with bean curd and water, take out, clean, smash to pieces, add water A little, superfine powder is ground into, is dried;
(29)Dens draconis:Outwash soil, smashes;
(Two)Prepare
(1)By the Poria cocos of the weight, prepared rhizome of rehmannia, Fructus Aurantii, the root of bidentate achyranthes, fructus alpiniae oxyphyllae, grass-leaved sweetflag, Radix Glycyrrhizae, polygala, balloonflower root, ginseng, hook Rattan, fushen, date, bark of ash, Radix Angelicae Sinensis, the root of herbaceous peony, moutan bark, Chinese yam, Fructus Corni, the fleece-flower root, sealwort, Morinda officinalis, Ligusticum wallichii, root tuber of aromatic turmeric, Semen Leonuri, the fruit of Chinese magnoliavine, tortoise version, pearl powder, dens draconis medicine are put into decocting container, are added water for the first time 8 times and are measured, and are soaked 60 minutes Afterwards, fry by intense fire to boil and rise, then with being cooked by slow fire 30 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into container It is interior;
(2)The dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with filtering in 20 minutes is cooked by slow fire, second decoction liquor fallen Enter in container;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, admixing medical solutions are obtained final product, is divided into 4 doses and is taken.
CN201611222508.1A 2016-12-27 2016-12-27 It is a kind of to treat medicine of encephalatrophy disease and preparation method thereof Withdrawn CN106729402A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108042750A (en) * 2018-01-29 2018-05-18 宋信东 Children's intelligence development spirit

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810814A (en) * 2010-04-28 2010-08-25 史建钢 Medicament for curing cerebral palsy, hyperkinetic syndrome and dementia and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101810814A (en) * 2010-04-28 2010-08-25 史建钢 Medicament for curing cerebral palsy, hyperkinetic syndrome and dementia and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108042750A (en) * 2018-01-29 2018-05-18 宋信东 Children's intelligence development spirit

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Application publication date: 20170531