CN107029163A

CN107029163A - It is a kind of to treat medicine of infantile enuresis and preparation method thereof

Info

Publication number: CN107029163A
Application number: CN201710298919.7A
Authority: CN
Inventors: 徐士魁
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-05-02
Filing date: 2017-05-02
Publication date: 2017-08-11

Abstract

The invention discloses a kind of medicine for treating infantile enuresis and preparation method thereof, it is mainly Radix Codonopsis, radix glehniae, the bighead atractylodes rhizome, radix rehmanniae recen, raspberry, mantis egg-case, hairyvein agrimony, Radix Angelicae Sinensis, grass-leaved sweetflag, polygala, the fruit of Chinese magnoliavine, oyster, Chinese yam, Semen Cuscutae, fructus alpiniae oxyphyllae, Fructus Corni, the root of three-nerved spicebush, prepared rhizome of rehmannia, radix glycyrrhizae and is prepared from according to a certain weight ratio, medicine of the present invention has filling liver kidney, reduce just, Gu collapse, supporing yang controlling nocturnal emission with astringent drugs, strengthening the spleen and tonifying the lung, the function of reinforce the kidney beneficial essence, for treating infantile enuresis instant effect, good effect, do not recur.

Description

It is a kind of to treat medicine of infantile enuresis and preparation method thereof

Technical field

The present invention relates to a kind of medicine for treating infantile enuresis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Infantile enuresis refers to that child started control urination at 3~4 years old, if also regular after 5~6 years old wet the bed, weekly The secondary above simultaneously lasts up to 6 months, is medically known as " enruesis ".Nocturnal enuresis is a kind of common disease, compares female in China boy It is high that child suffers from this sick probability.Infantile enuresis is divided into primary and secondary enuresis, and primary enuresis refers to children from as low as going to a doctor Shi Yizhi has the enuresis, and secondary enuresis refers to that children once stopped enuresis at least six month, occurred the enuresis again later.Due to west Medicine treatment side effect is big, therefore people have great demand to the Chinese medicine of effectively treatment infantile enuresis, up to now, also The relevant report on the present invention is not found.

The content of the invention

Repeatedly checking of the present inventor according to research and the clinical test of theory of traditional Chinese medical science, have found effectively treatment children finally The medicine of the enuresis, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment infantile enuresis.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention is selection Radix Codonopsis, radix glehniae, the bighead atractylodes rhizome, radix rehmanniae recen, raspberry, mantis egg-case, hairyvein agrimony, Radix Angelicae Sinensis, stone Calamus, polygala, the fruit of Chinese magnoliavine, oyster, Chinese yam, Semen Cuscutae, fructus alpiniae oxyphyllae, Fructus Corni, the root of three-nerved spicebush, prepared rhizome of rehmannia, radix glycyrrhizae, keel, the fruit of Chinese wolfberry, Malt, cassia twig are combined preparation, cause each efficacy of drugs to produce synergy these drug regimens, so as to effective Treat infantile enuresis.Wherein it is, because its nature and flavor is sweet, to put down, start with, meridian of Foot-TAI YIN qi leel, have tonifying middle-Jiao and Qi, promote the production of body fluid from Radix Codonopsis Function, control weakness of the spleen and the stomach, qi-blood deficiency, body is tired powerless, deficiency of food is thirsty, chronic diarrhea, prolapse of the anus.It is from radix glehniae because its property Sweet-bitter flavor is light, cool, enters lung, the spleen channel, there is a nourishiing yin to clear away the lung-heat, the function of expelling phlegm and arresting coughing, controls lung-heat type cough, consumptive disease chronic cough, impairment of yin dry throat, It is thirsty.Be the temperature because its nature and flavor bitter sweet from the bighead atractylodes rhizome, enter spleen, stomach, there is a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control taste Gas is weak, do not feel like eating, and the few gas of burnout, empty swollen, diarrhea, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, spontaneous perspiration, nausea It is uneasy.It is, because its nature and flavor is sweet, to tremble with fear, the thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, and yin-nourishing, the function of promoting the production of body fluid controls heat from radix rehmanniae recen Sick polydipsia, yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.It is from raspberry because its nature and flavor Sweet, acid is put down, enter liver, kidney two warp, there is filling liver kidney, is reduced just, supporing yang, controlling nocturnal emission with astringent drugs, the function of improving eyesight controls impotence, seminal emission, and number of urinating is lost Drown, consumptive disease, mesh is dark.It is, because its nature and flavor is salty, sweet, flat, to there is kidney tonifying from mantis egg-case, the function of controlling nocturnal emission with astringent drugs controls seminal emission, gonorrhoea, sun Impotence, premature ejaculation.It is, because its nature and flavor toil, to put down, enter lung, liver, the spleen channel, there is hemostasis, the function of stomach invigorating controls spitting of blood from hairyvein agrimony, Spit blood, hematuria is had blood in stool, dysentery, under uterine bleeding band, internal lesion caused by overexertion takes off power, carbuncle swells, bruise, traumatic bleeding.It is because of it from Radix Angelicae Sinensis Nature and flavor sweet, acrid, warm, enters the heart, liver, the spleen channel, there is benefiting blood and regulating blood circulation, and menstruction regulating and pain relieving, the function of moisturize laxation controls irregular menstruation, Amenorrhea abdomen Tong , Disorder lumps in the abdomen knot gathers, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness is difficult just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool. It is that tepor enters the heart, liver, the spleen channel, has and have one's ideas straightened out, slit phlegm, qi-regulating because its nature and flavor is worked hard from grass-leaved sweetflag, promoting blood circulation dissipates wind, dried Function, Zhi Dian Epilepsy, coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition is unhappy, has a stomachache, stomachache, wind-cold-dampness arthralgia, ulcer swells Poison, traumatic injury.It is the temperature because its nature and flavor toil from polygala, enters the heart, kidney channel, there is a tranquilize the mind and promote the intelligence, eliminating the phlegm, Xie Yu function, Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, ulcer sore swells.It is because its nature and flavor acid, temperature, enter lung, kidney from the fruit of Chinese magnoliavine Through astringing the lung, nourshing kidney is promoted the production of body fluid, receiving sweat, puckery smart function is controlled the deficiency syndrome of the lung and breathed with cough, thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin thin, dream Lose involuntary emission, protracted dysentery and diarrhea.Be from oyster because its nature and flavor is salty and bitter, it is cool, enter liver and kidney channel, hold back the moon, checking exuberance of yang, hidroschesis, puckery essence, Under resolving sputum, the function of softening hard masses, Zhi Jing Epilepsy, dizziness, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, uterine bleeding, band, scrofula, goiter and tumor.From Chinese yam It is, because its nature and flavor is sweet, to put down, enter lung, spleen, kidney channel, there is invigorating the spleen, tonifying lung is reinforced the kidney, the function of strengthening the essence, controls splenasthenic diarrhea, protracted dysentery is empty Impairment and cough, quenches one's thirst, under seminal emission, band, frequent urination.It is, because its property acrid-sweet flavor, to put down, enter liver and kidney channel, there is tonifying liver from Semen Cuscutae Kidney, benefiting quintessence, the function of improving eyesight controls soreness of waist and knee joint, seminal emission, quenches one's thirst, dripping urination, mesh is dark.It is from fructus alpiniae oxyphyllae because its property Pungent, temperature enters spleen, kidney channel, there is warm spleen, warms up kidney, and solid and gas, puckery smart function controls cold air stomachache, and syncope due to pathogenic cold is vomited and diarrhoea, many salivas, seminal emission, Dribbling urination, many nights many urine.It is, because its nature and flavor acid, tepor enters liver and kidney channel, to there is a filling liver kidney from Fructus Corni, puckery vital essence, Gu The function of collapse, controls soreness of waist and knee joint, and dizziness, tinnitus, impotence, seminal emission, frequent urination, liver cold of insufficiency type heat, incessant sweating due to debility, the heart shakes arteries and veins Dissipate.It is that, because its nature and flavor is pungent, temperature enters spleen, lung, kidney, bladder warp, there is pleasant, open strongly fragrant, cold dispelling, the function of analgesic is controlled from the root of three-nerved spicebush Circulation of vital energy in the wrong direction chest and abdomen swelling and pain, place food is discontented, regurgitation and emesis, cold hernia, tinea pedis, frequent urination.From prepared rhizome of rehmannia be because its nature and flavor it is sweet, it is micro- Temperature, enters liver and kidney channel, there is enriching yin, the function of enriching blood, and it is few to control deficiency of Yin blood, waist knee flaccidity, Cough osteopyrexia, seminal emission, uterine bleeding, and menstruation is not Adjust, quench one's thirst, number of urinating is deaf, blurred vision.Because its property sweet taste, to enter spleen, stomach, lung channel from radix glycyrrhizae, have with middle emergency, moistening lung, Removing toxic substances, the function of coordinating the drug actions of a prescription processs, deficiency of food weakness of the spleen and the stomach with controlling, and loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, palpitaition shies carbuncle, It is raw with controlling abscess of throat, peptic ulcer, ulcer sores and are poisoned by food at antidote poison.From keel be because its property sweet-puckery flavor, It is flat, the heart, liver, kidney, large intestine channel are included into, there is tranquillizing the mind by relieving convulsion, the function of arrest sweating controlling nocturnal emission with astringent drugs, Zhi Jing Epilepsy is demented, and palpitation is forgetful, is had a sleepless night many Dream, spontaneous sweating.It is, because its nature and flavor is sweet, to put down, have nourshing kidney, moistening lung, tonifying liver, the function of improving eyesight controls liver kidney yin from the fruit of Chinese wolfberry Thanks to, soreness and weakness of waist and knees, is had a dizzy spell, and many tears of blurred vision, cough due to consumptive disease is quenched one's thirst, and loses clear.It is the tepor because its nature and flavor is sweet from malt, Enter spleen, stomach, have and help digestion, and in, the function of lower gas controls dyspepsia, and abdominal fullness and distention is lost the appetite, vomiting and diarrhea, and mammary swelling is not Disappear.It is that, because its property acrid-sweet flavor, temperature enters bladder, the heart, lung channel, there is sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi controls wind from cassia twig Cold exterior syndrome, shoulder back of the body podomere ache, obstruction of qi in the chest phlegm and retained fluid, Jing Bi Disorder lumps in the abdomen.

Embodiment

The drug dose of instant component is also that inventor's process largely gropes to summarize what is drawn, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

5-15 grams of Radix Codonopsis, 5-15 grams of radix glehniae, 5-15 grams of the bighead atractylodes rhizome, 5-15 grams of radix rehmanniae recen, 5-15 grams of raspberry, mantis egg-case 5-15 Gram, 5-15 grams of hairyvein agrimony, 4-8 grams of Radix Angelicae Sinensis, 4-8 grams of grass-leaved sweetflag, 5-10 grams of polygala, 3-5 grams of the fruit of Chinese magnoliavine, 5-15 grams of oyster, Chinese yam 5-15 grams, 10-15 grams of Semen Cuscutae, 4-8 grams of fructus alpiniae oxyphyllae, 5-15 grams of Fructus Corni, 7-11 grams of the root of three-nerved spicebush, 7-11 grams of prepared rhizome of rehmannia, radix glycyrrhizae 3-5 Gram, 5-15 grams of keel, 6-10 grams of the fruit of Chinese wolfberry, 7-11 grams of malt, 6-10 grams of cassia twig.

Preferably：

10 grams of Radix Codonopsis, 10 grams of radix glehniae, 10 grams of the bighead atractylodes rhizome, 10 grams of radix rehmanniae recen, 10 grams of raspberry, 10 grams of mantis egg-case, 10 grams of hairyvein agrimony, 6 grams of Radix Angelicae Sinensis, 6 grams of grass-leaved sweetflag, 5 grams of polygala, 3 grams of the fruit of Chinese magnoliavine, 10 grams of oyster, 10 grams of Chinese yam, 12 grams of Semen Cuscutae, 6 grams of fructus alpiniae oxyphyllae, mountain 10 grams of the fruit of medicinal cornel, 9 grams of the root of three-nerved spicebush, 9 grams of prepared rhizome of rehmannia, 3 grams of radix glycyrrhizae, 10 grams of keel, 8 grams of the fruit of Chinese wolfberry, 9 grams of malt, 8 grams of cassia twig.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Radix Codonopsis：Clean and reed is run through after silt, section or segment are dried；

2nd, radix glehniae：Impurity is picked, stem foot is removed, is slightly washed, pulled out with water, slightly moistened, segment is dried；

3rd, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, is pulled out after bubble, is run through, cuts into slices, dries；

4th, radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dries, weeds out chip；

5th, raspberry：Grey bits are weeded out, net impurity is picked, removes handle；

6th, mantis egg-case：By net mantis egg-case and wheat bran with frying to strong yellow, take out, weed out wheat bran, cool；

7th, hairyvein agrimony：Impurity undesirable root is removed, cleans, runs through, cuts off, dries；

8th, Radix Angelicae Sinensis：Pick impurity, clean, vexed profit, slightly dry in the air to inside and outside humidity it is suitable when, section is dried；

9th, grass-leaved sweetflag：Impurity is picked, is cleaned, is soaked, run through slightly, cuts into slices, dries；

10th, polygala：Impurity is picked, segment weeds out grey bits；

11st, the fruit of Chinese magnoliavine：Grey bits are weeded out, impurity is removed, puts and steams saturating in food steamer, taking-up is dried；

12nd, oyster：Clean, dry, smash use；

13rd, Chinese yam：Net impurity is picked, it is degree to be soaked in water to the softening of Chinese yam central part, pulls out and slightly dries in the air, section is dried or dried；

14th, Semen Cuscutae：Cross square-bottomed bamboo basket and remove impurity, clean, dry；

15th, fructus alpiniae oxyphyllae：Take fructus alpiniae oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take benevolence to smash use to pieces；

16th, Fructus Corni：Clean, except removal core and impurity, dry；

17th, the root of three-nerved spicebush：Impurity is picked, size bar is separated, is noted changing water according to season, prevents smelly, pulled out cut in time with bubble thoroughly Piece, weeds out grey bits；

18th, prepared rhizome of rehmannia：Take crude drug, steam to surface corvinus, take out, shine to eighty per cant it is dry when, cut into slices, dry；

19th, radix glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；

20th, keel：Outwash soil, is smashed；

21st, the fruit of Chinese wolfberry：Winnow with a dustpan net impurity, pluck the stalk and the base of a fruit of residual；

22nd, malt：Taking malt to put in pot, micro- stir-fry is to yellow, and taking-up is cooled；

23rd, cassia twig：Slightly soaked, pulled out with water, vexed profit is dried to saturating, section, weeds out bits.

2nd, prepare

1st, by the Radix Codonopsis of the weight, radix glehniae, the bighead atractylodes rhizome, radix rehmanniae recen, raspberry, mantis egg-case, hairyvein agrimony, Radix Angelicae Sinensis, grass-leaved sweetflag, remote Will, the fruit of Chinese magnoliavine, oyster, Chinese yam, Semen Cuscutae, fructus alpiniae oxyphyllae, Fructus Corni, the root of three-nerved spicebush, prepared rhizome of rehmannia, radix glycyrrhizae, keel, the fruit of Chinese wolfberry, malt, osmanthus Branch is put into decocting container, is added water 6 times and is measured, after soaking 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, is filtered First time decoction liquor is obtained, first time decoction liquor is poured into container；

2nd, the dregs of a decoction of filtering are added water 4 times and measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

3rd, it decoction liquor will be mixed evenly twice, and be divided into 6 doses and take.

Raspberry has filling liver kidney in prescription, reduces just, supporing yang, and the function of controlling nocturnal emission with astringent drugs is monarch drug in a prescription；Mantis egg-case has kidney tonifying, controlling nocturnal emission with astringent drugs Function；Chinese yam has invigorating the spleen, and tonifying lung is reinforced the kidney, the function of strengthening the essence, and the two is ministerial drug, and three taste medicines play filling liver kidney jointly, reduces just, Supporing yang controlling nocturnal emission with astringent drugs, strengthening the spleen and tonifying the lung, the effect of reinforce the kidney beneficial essence, treatment infantile enuresis effect comprehensively, and with filling liver kidney, reduces just, reinforced the kidney It can be effected a permanent cure based on strengthening the essence, Fructus Corni has filling liver kidney, puckery vital essence, admittedly the function of collapsing is adjutant, the root of three-nerved spicebush has pleasant, opens strongly fragrant, cold dispelling, The function of analgesic is makes medicine, and all medicines are to take stopgap measures with being left.

Medicine of the present invention has filling liver kidney, reduces just, Gu collapse, supporing yang controlling nocturnal emission with astringent drugs, strengthening the spleen and tonifying the lung, the function of reinforce the kidney beneficial essence, For treating infantile enuresis, short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, even served 7 days, the reaction of observation administration daily, as a result show that two groups of rabbit activities, diet are normal, medicine is without bad Toxic side effect.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, general information

Accept infantile enuresis out-patient totally 36 for medical treatment.

2nd, diagnostic criteria

Infantile enuresis is in the great majority with primary enuresis, wherein it is especially most common with enuresis nocturna, it is common with boy；Enuresis nocturna person It there are about half to wet the bed every night, or even the enuresis 2~3 times every night, often lost after excessive daytime activity, excitement, fatigue or physical disease Increased frequency is urinated, the enuresis is more rare in the daytime.Enuresis infant is usually with sleep terror fright at night, sleep-walking, many dynamic or other behavior disorders.

3rd, treatment method

From above-mentioned medicament, taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, is within 10 days a course for the treatment of, continuously Take 2 courses for the treatment of.

4th, efficacy assessment standard

It is effective：Infantile enuresis symptom disappears, recovery from illness；

Take a turn for the better：Infantile enuresis symptom is clearly better, and sleep terror fright at night, daydream, bed-wetting number of times are reduced, and progressively recovers normal；

It is invalid：Improvement standard person is not reached.

5th, treatment results（It see the table below）

In above-mentioned treatment, with drug therapy infantile enuresis patient 36 of the present invention, as a result effective 29, obvious effective rate is 80.6%, Take a turn for the better 5, improvement rate is 13.9%, and invalid 2, total effective rate is 94.5%.

Claims

1. a kind of medicine for treating infantile enuresis, it is characterised in that：Its bulk drug in following weight range is made：

2. medicine according to claim 1, wherein the consumption of each bulk drug is：

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Radix Codonopsis：Clean and reed is run through after silt, section or segment are dried；

（2）Radix glehniae：Impurity is picked, stem foot is removed, is slightly washed, pulled out with water, slightly moistened, segment is dried；

（3）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, is pulled out after bubble, is run through, cuts into slices, dries；

（4）Radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dries, weeds out chip；

（5）Raspberry：Grey bits are weeded out, net impurity is picked, removes handle；

（6）Mantis egg-case：By net mantis egg-case and wheat bran with frying to strong yellow, take out, weed out wheat bran, cool；

（7）Hairyvein agrimony：Impurity undesirable root is removed, cleans, runs through, cuts off, dries；

（8）Radix Angelicae Sinensis：Pick impurity, clean, vexed profit, slightly dry in the air to inside and outside humidity it is suitable when, section is dried；

（9）Grass-leaved sweetflag：Impurity is picked, is cleaned, is soaked, run through slightly, cuts into slices, dries；

（10）Polygala：Impurity is picked, segment weeds out grey bits；

（11）The fruit of Chinese magnoliavine：Grey bits are weeded out, impurity is removed, puts and steams saturating in food steamer, taking-up is dried；

（12）Oyster：Clean, dry, smash use；

（13）Chinese yam：Net impurity is picked, it is degree to be soaked in water to the softening of Chinese yam central part, pulls out and slightly dries in the air, section is dried or dried；

（14）Semen Cuscutae：Cross square-bottomed bamboo basket and remove impurity, clean, dry；

（15）Fructus alpiniae oxyphyllae：Take fructus alpiniae oxyphyllae to put in pot, fry burned black to shell, take out cold, remove shell, take benevolence to smash use to pieces；

（16）Fructus Corni：Clean, except removal core and impurity, dry；

（17）The root of three-nerved spicebush：Impurity is picked, size bar is separated, is noted changing water according to season, prevents smelly, pull out in time with bubble thoroughly Section, weeds out grey bits；

（18）Prepared rhizome of rehmannia：Take crude drug, steam to surface corvinus, take out, shine to eighty per cant it is dry when, cut into slices, dry；

（19）Radix glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；

（20）Keel：Outwash soil, is smashed；

（21）The fruit of Chinese wolfberry：Winnow with a dustpan net impurity, pluck the stalk and the base of a fruit of residual；

（22）Malt：Taking malt to put in pot, micro- stir-fry is to yellow, and taking-up is cooled；

（23）Cassia twig：Slightly soaked, pulled out with water, vexed profit is dried to saturating, section, weeds out bits；

（Two）Prepare

（1）By the Radix Codonopsis of the weight, radix glehniae, the bighead atractylodes rhizome, radix rehmanniae recen, raspberry, mantis egg-case, hairyvein agrimony, Radix Angelicae Sinensis, grass-leaved sweetflag, Polygala, the fruit of Chinese magnoliavine, oyster, Chinese yam, Semen Cuscutae, fructus alpiniae oxyphyllae, Fructus Corni, the root of three-nerved spicebush, prepared rhizome of rehmannia, radix glycyrrhizae, keel, the fruit of Chinese wolfberry, malt, Cassia twig is put into decocting container, is added water 6 times and is measured, after immersion 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, mistake First time decoction liquor is filtered to obtain, first time decoction liquor is poured into container；

（2）The dregs of a decoction of filtering are added water 4 times and measured, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

（3）It decoction liquor will be mixed evenly twice, and be divided into 6 doses and take.