CN108404091A - A kind of drug and preparation method thereof for treating cardiac arrhythmia - Google Patents

Abstract

The invention discloses a kind of drugs and preparation method thereof for treating cardiac arrhythmia, it is mainly by spina date seed, Radix Angelicae Sinensis, the seed of Oriental arborvitae, rhizoma zingiberis, psoralea corylifolia, thizoma curculiginis, Herba Cistanches, Radix Astragali, Radix Polygalae, grass-leaved sweetflag, Radix Glehniae, lily, pyrola, radix pseudostellariae, ginseng, Rhizoma Chuanxiong, caulis bambusae in taenian, Artemisia capillaris, uncaria, rhizoma anemarrhenae, Caulis Spatholobi, Rhizoma Atractylodis Macrocephalae, cassia twig, Morinda officinalis, safflower, rhizoma atractylodis, Poria cocos, Radix Ophiopogonis is prepared according to a certain weight ratio, drug of the present invention has antitoxic heart-soothing and sedative, benefiting blood and regulating blood circulation, middle benefit gas is by cold, recover Yang and smooth venation, the function of prevent prolapse and engender liquid, it is quick for treating cardiac arrhythmia, good effect, it does not recur.

Description

A kind of drug and preparation method thereof for treating cardiac arrhythmia

Technical field

The present invention relates to a kind of drugs and preparation method thereof for treating cardiac arrhythmia, belong to the field of Chinese medicines.

Technical background

Cardiac arrhythmia refers to that heartbeat is fast or slow, has been more than general range.Abnormality of cardiac automaticity or conductive impairment draw Tachycardia, bradycardia or the cardiac arrhythmia risen.Chinese medicine then thinks cardiac arrhythmia and qi depression to blood stasis, deficiency of heart-YANG, qi and blood two Empty, exopathogen invasion, feelings will are hindered related.Since western medicine side effect is big, people are to effectively treating in cardiac arrhythmia There are great demands for medicine drug, up to now, it has not been found that the related report about the present invention.

Invention content

Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found the effectively treatment rhythm of the heart Uneven drug, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment cardiac arrhythmia.

Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.

The present invention is selection spina date seed, Radix Angelicae Sinensis, the seed of Oriental arborvitae, rhizoma zingiberis, psoralea corylifolia, thizoma curculiginis, Herba Cistanches, Radix Astragali, Radix Polygalae, stone Chang Pu, Radix Glehniae, lily, pyrola, radix pseudostellariae, ginseng, Rhizoma Chuanxiong, caulis bambusae in taenian, Artemisia capillaris, uncaria, rhizoma anemarrhenae, Caulis Spatholobi, Rhizoma Atractylodis Macrocephalae, osmanthus Branch, Morinda officinalis, safflower, rhizoma atractylodis, Poria cocos, Radix Ophiopogonis, Schisandra chinensis, tea root, Ramulus Taxilli drug are combined preparation, by these medicines Object combines so that each efficacy of drugs generates synergistic effect, so as to effectively treat cardiac arrhythmia.Wherein, select spina date seed be because For its nature and flavor sweet and neutral, enter the heart, spleen, liver, gallbladder channel, there is nourishing the liver, calming heart to calm the nerves, the function of arrest sweating controls restlessness of asrhenia type and insomnia, and palpitation with fear is seized with terror It is sad, polydipsia, abnormal sweating.It is to enter the heart, liver, the spleen channel because of its nature and flavor sweet, acrid, warm to select Radix Angelicae Sinensis, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, profit The function of dry laxation controls irregular menstruation, and Amenorrhea abdominal pain , Disorder lump in the abdomen knots are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness difficulty is just, red Weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery.It is to enter the heart, liver, the spleen channel because of its nature and flavor sweet and neutral, there is nourishing heart to select the seed of Oriental arborvitae Calm the nerves, the function of relaxing bowel controls palpitation with fear, has a sleepless night, seminal emission, night sweat, the function of constipation.Select rhizoma zingiberis be because its nature and flavor it is pungent, Heat enters spleen, stomach, lung channel, has middle benefit gas by trembling with fear, and the function of recover Yang and smooth venation controls trusted subordinate's crymodynia, vomits and diarrhoea, and cold weak pulse of limb, cold drink is breathed with cough, Wind-cold-dampness arthralgia, the deficiency of yang spits, is defeated in battle, lower blood.Psoralea corylifolia is because its nature and flavor is acrid in flavour and warm in nature.Enter kidney channel.It tonifies the kidney and support yang.It controls that kidney deficiency is cold to rush down, loses Urine, involuntary emission, frequent urination, positive fistula, waist and knee crymodynia, cold of insufficiency type asthma are coughed.Select thizoma curculiginis be because its nature and flavor it is acrid in flavour and warm in nature, it is toxic, enter kidney, Liver Channel has warm kidney positive, and the function of strengthening the bone controls impotence cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula Scrofula.It is because its nature and flavor sweet acid is salty to select Herba Cistanches, and temperature enters kidney, large intestine channel, has kidney tonifying, strengthening the essence to moisturize, the function of gut purge is controlled Impotence in male, female sterility, under, metrorrhagia, waist and knee crymodynia, blood depletion constipation.It is because its nature and flavor is sweet to select Radix Astragali, and tepor enters Lung, the spleen channel, raw with there is an invigorating qi for consolidating superficies, inducing diuresis for removing edema, eliminating toxic, the function of myogenic control spontaneous perspiration, and night sweat, blood-arthralgia, edema, ulcer is not Routed or prolonged fester before gathering；The toast function of having bowl spares benefit controls internal injury overstrain, and splenasthenic diarrhea, rectal prolapse, deficiency of vital energy blood is de-, collapses band and all gas The disease for the deficiency of blood that declines.It is to enter the heart, kidney channel because its is bitter in taste acrid in flavour and warm in nature to select Radix Polygalae, there is a tranquilize the mind and promote the intelligence, eliminating the phlegm, the function of Xie Yu, Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, ulcer sore swells.It is the tepor because its nature and flavor is arduous to select grass-leaved sweetflag, enter the heart, Liver, the spleen channel, have and have one's ideas straightened out, slit phlegm, qi-regulating, and promoting blood circulation, relieve heat, the function of drying, Zhi Dian Epilepsy, coma due to blocking of the respiratory system, pyreticosis coma is forgetful, gas-tight Deafness, ambition is unhappy, stomachache, abdominal pain, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.It is because of its nature and flavor sweetness and bitterness to select Radix Glehniae It is light, it is cool, enter lung, the spleen channel, there is a nourishiing yin to clear away the lung-heat, the function of expelling phlegm and arresting coughing controls lung-heat type cough, consumptive disease chronic cough, impairment of yin dry throat, thirsty. It is to put down because of its property sweet and slightly bitter taste, enter the heart, lung channel, moisten the lung and relieve the cough to select lily, and the function of clearing away the heart fire and tranquillizing controls tuberculosis and coughs long, Cough saliva phlegm blood, waste heat is not clear after pyreticosis, and dysphoria palpitates with fear is wandering, beriberi edema.It is because its nature and flavor is sweet to select pyrola Hardship, temperature, enters liver, kidney two warp, there is a qi-restoratives, kidney-nourishing, dispelling wind and eliminating dampness, and the function of promoting blood circulation for regulating menstruation controls weak cough, over-strained hemoptysis, wind Wet arthralgia, uterine bleeding, leukorrhea, traumatic hemorrhage.It is the tepor because of its nature and flavor sweetness and bitterness to select radix pseudostellariae, enters the heart, spleen, lung three and passes through, has Tonifying lung, the function of invigorating the spleen control cough due to deficiency of the lung, spleen eating less, palpitaition mesh sweat, metal fatigue.It is because its nature and flavor is sweet to select ginseng Micro- sweet, warm enters spleen, lung channel, reinforces vital energy, prevent prolapse and engender liquid, the function of tranquilizing the mind, and it is deficient to control internal lesion caused by overexertion, deficiency of food, burnout, and gastric disorder causing nausea is spat Food, lingering diarrhea of defecating, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition are quenched one's thirst, woman uterine bleeding, children Slow frightened and perennial and irrecoverable weakness, the disease of all qi-blood-body fluid deficiencies.It is to enter liver, gallbladder channel because its nature and flavor is acrid in flavour and warm in nature, there is row to select Rhizoma Chuanxiong Gas is opened strongly fragrant, dispels pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain, and it is dizzy to control air-cooled headache rotation, hypochondriac pain abdomen pain, arthritis muscle contraction, and Amenorrhea is had difficult labour, production Stasis blocking block pain afterwards, ulcer sores.Select caulis bambusae in taenian be because its nature and flavor it is sweet, it is cool, enter stomach, gallbladder channel, there is heat-clearing, cool blood, resolving sputum, antiemetic Function, control dysphoria with smothery sensation vomiting, hiccup, phlegm heat-syndrome cough asthma, spit blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, vomiting during early pregnancy, movement of the foetus , Jing Epilepsy.Select Artemisia capillaris be because It is cool for its nature and flavor toil, enter liver, spleen, bladder warp, there is the function of clearing heat and promoting diuresis, controls jaundice with damp-heat pathogen, difficult urination, pruritus sore scabies. Select uncaria be because its is bitter in taste, it is cool, enter liver, the heart channel of Hang-Shaoyin, there is The flat liver of heat-clearing, the function for the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. controls little Jing Epilepsy Chi Zong, Adult's slight Hypertension, dizzy, dizzy, married woman's sub- Epilepsy.It is to tremble with fear because its is bitter in taste, enter lung, stomach, kidney channel, there is enriching yin to select rhizoma anemarrhenae Fall fire, the function of moisturize laxation control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.Select Caulis Spatholobi Be because of its sweet, warm bitter in taste, enter the heart, spleen two passes through, have promoting blood circulation, relaxing muscles and tendons function, control soreness of waist and knee joint, paralysis and numbness, menstruation is not It adjusts.It is to enter spleen, stomach because of its sweet, warm bitter in taste to select Rhizoma Atractylodis Macrocephalae, there is a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control taste gas Weak, do not feel like eating, burnout lacks gas, and empty swollen, diarrhea, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination, dizzy, spontaneous perspiration, nausea is not Peace.It is to enter bladder, the heart, lung channel because of the pungent sweet, warm of its nature and flavor, have sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control wind to select cassia twig Cold exterior syndrome, shoulder carry on the back podomere ache, obstruction of qi in the chest phlegm and retained fluid, Jing Bi Disorder lumps in the abdomen.It is to enter liver, kidney because of the pungent sweet, warm of its nature and flavor to select Morinda officinalis Through having kidney-replenishing, strengthening the bone, the function of wind-damp dispelling controls impotence, and few abdomen crymodynia, urinary incontinence, uterus void is cold, wind-cold-dampness arthralgia, waist Knee joint soreness.It is to enter the heart, Liver Channel because its nature and flavor is acrid in flavour and warm in nature, there is an invigorate blood circulation to select safflower, the function of stasis eliminatings analgesic, controlling through closing, Disorder lumps in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.Selecting rhizoma atractylodis is worked hard because of its nature and flavor, Temperature enters spleen, stomach, has invigorating the spleen, eliminating dampness, Xie Yu to ward off dirty function, controls wet soreness, burnout, gastral cavity ruffian abdominal distension, appetite is not It shakes, vomits, diarrhea, dysentery, malaria, phlegm and retained fluid, oedema, feel cold, wind-cold-dampness arthralgia, atrophy, yctalopia.It is because of it to select Poria cocos Property slightly sweet flavor, put down, enter the heart, spleen, lung channel, there is eliminating dampness and diuresis, it is swollen to control difficult urination oedema for beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative Bitterly, phlegm and retained fluid cough is inverse, the sound of vomiting of vomitting, diarrhea, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Selecting Radix Ophiopogonis is trembled with fear because of its property sweet and slightly bitter taste, enter lung, Stomach, the heart channel of Hang-Shaoyin have Yin nourishing and lung moistening, relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid to control dryness of the lung dry cough, spit blood, spitting of blood, consumptive lung disease, and lung carbuncle is empty Labor dysphoria with smothery sensation, clear thirsty, pyreticosis Tianjin wound, dry throat, constipation.It is because its nature and flavor acid, temperature enter lung, kidney channel, hold back to select Schisandra chinensis Lung, nourshing kidney are promoted the production of body fluid, and sweat is received, and the function of puckery essence controls the deficiency syndrome of the lung and breathes with cough, and thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin thin, emission, Protracted dysentery and diarrhea；It is to put down because its is bitter in taste, control heart disease, aphtha, psoriasis to select tea root.It is because of it to select Ramulus Taxilli Sweet and neutral bitter in taste, enters liver and kidney channel, there is a filling liver kidney, strengthening the bones and muscles, curing rheumatism, degrading the channel, beneficial blood, the function of tocolysis, controls waist and knee acid Bitterly, muscles and bones impotence is weak, hemiplegia, tinea pedis, wind-cold-dampness arthralgia, threatened abortion metrorrhagia, lack of lactation after delivery.

Specific implementation mode

The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy All tools have a better effect in amount range：

15-20 grams of spina date seed, 10-20 grams of Radix Angelicae Sinensis, 10-15 grams of the seed of Oriental arborvitae, 5-10 grams of rhizoma zingiberis, 10-15 grams of psoralea corylifolia, thizoma curculiginis 10- 20 grams, 10-20 grams of Herba Cistanches, 5-15 grams of Radix Astragali, 5-10 grams of Radix Polygalae, 5-15 grams of grass-leaved sweetflag, 10-20 grams of Radix Glehniae, lily 10-15 Gram, 10-20 grams of pyrola, 5-15 grams of radix pseudostellariae, 5-10 grams of ginseng, 5-15 grams of Rhizoma Chuanxiong, 3-9 grams of caulis bambusae in taenian, 5-10 grams of Artemisia capillaris, hook 5-15 grams of rattan, 5-10 grams of rhizoma anemarrhenae, 5-15 grams of Caulis Spatholobi, 5-10 grams of Rhizoma Atractylodis Macrocephalae, 10-20 grams of cassia twig, 10-15 grams of Morinda officinalis, safflower 5- 10 grams, 10-15 grams of rhizoma atractylodis, 10-20 grams of Poria cocos, 5-15 grams of Radix Ophiopogonis, 5-10 grams of Schisandra chinensis, 10-20 grams of tea root, Ramulus Taxilli 5-10 Gram.

Preferably：

18 grams of spina date seed, 15 grams of Radix Angelicae Sinensis, 12 grams of the seed of Oriental arborvitae, 8 grams of rhizoma zingiberis, 12 grams of psoralea corylifolia, 15 grams of thizoma curculiginis, 15 grams of Herba Cistanches, Huang 10 grams of stilbene, 8 grams of Radix Polygalae, 10 grams of grass-leaved sweetflag, 15 grams of Radix Glehniae, 12 grams of lily, 15 grams of pyrola, 10 grams of radix pseudostellariae, 8 grams of ginseng, 10 grams of Rhizoma Chuanxiong, 6 grams of caulis bambusae in taenian, 8 grams of Artemisia capillaris, 10 grams of uncaria, 8 grams of rhizoma anemarrhenae, 10 grams of Caulis Spatholobi, 8 grams of Rhizoma Atractylodis Macrocephalae, 15 grams of cassia twig, Morinda offcinalis How It 12 grams, 8 grams of safflower, 12 grams of rhizoma atractylodis, 15 grams of Poria cocos, 10 grams of Radix Ophiopogonis, 8 grams of Schisandra chinensis, 15 grams of tea root, 8 grams of Ramulus Taxilli.

The preparation method of drug of the present invention is as follows

One, it stocks up

1, spina date seed：Active compound is put into bamboo basket, sinks in clear water cylinder, benevolence is made to keep afloat, and thorn benevolence is pulled out, shone by the heavy bottom of shell It is dry；

2, Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；

3, the seed of Oriental arborvitae：Net impurity is picked, remaining shell and kind skin are removed；

4, rhizoma zingiberis：Net impurity is picked, is soaked in water 3-6 hours, pulls out, be sliced or dice after bored profit, dry；

5, psoralea corylifolia：It winnows with a dustpan most impurity, cleans, dry；

6, thizoma curculiginis：It takes net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after moisturizing, sets micro- stir-fry in pot and take out, dry to doing；

7, Herba Cistanches：Net impurity is picked, clear water impregnates, changes water 1-2 times a day, be such as salty desert cistanche, steeps salinity to the greatest extent, moisturizes, longitudinally cut Piece dries；

8, Radix Astragali：Net impurity is picked, remaining head and hollow the greater is removed, is soaked in water, pulls out, is sliced in time after moisturizing, It dries；

9, Radix Polygalae：Impurity is picked, segment weeds out grey bits；

10, grass-leaved sweetflag：Impurity is picked, is cleaned, is impregnated, moisturize slightly, is sliced, dries；

11, Radix Glehniae：Impurity is picked, stem foot is removed, is slightly washed with water, pull out, slightly moisten, segment is dried；

12, lily：Pick impurity, black valve, ash disposal of winnowing with a dustpan bits；

13, pyrola：Impurity is picked, silt is weeded out, is cleaned, is slightly moistened, chop up, dry；

14, radix pseudostellariae：Fibrous root is extractd, is dried；

15, ginseng：Except removing LU, segment；

16, Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；

17, caulis bambusae in taenian：Hard bamboo stick, impurity are removed, grey bits are shaked off, is kneaded into small group or segment；

18, Artemisia capillaris：Sieving picks impurity, removes undesirable root, pulverizes, spare is removed after square-bottomed bamboo basket；

19, uncaria：Old stalk, impurity are picked, cleans, dries；

20, rhizoma anemarrhenae：Net impurity is picked, is hit and is washed with water, is pulled out, is softened, slice dries；

21, Caulis Spatholobi：Moisturized with water, be sliced, or steam it is soft after multiply fervent piece, dry；

22, Rhizoma Atractylodis Macrocephalae：Net impurity is picked, is soaked in water, is pulled out after bubble, is moisturized, is sliced, dries；

23, cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；

24, Morinda officinalis：Impurity is picked, after being soaked with hot water, pumps core while hot, segment is dried；

25, safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dries；

26, rhizoma atractylodis：Impurity is picked, thoroughly with bubble to seven, eighty per cant, pulls out, is sliced, dries after moisturizing；

27, Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；

28, Radix Ophiopogonis：Net impurity is picked, is soaked in water, is pulled out, the heart is pumped after moisturizing, then clean and dry；

29, Schisandra chinensis：Grey bits are weeded out, impurity is removed, sets in food steamer and steams thoroughly, taking-up is dried；

30, tea root：Crude drug is taken, impurity is removed, is cleaned, is moisturized, cut sheet, it is dry, weed out clast；

31, Ramulus Taxilli：It is eluted with water, moisturizes, segment is dried.

Two, it prepares

1, by the spina date seed of the weight, Radix Angelicae Sinensis, the seed of Oriental arborvitae, rhizoma zingiberis, psoralea corylifolia, thizoma curculiginis, Herba Cistanches, Radix Astragali, Radix Polygalae, stone Chang Pu, Radix Glehniae, lily, pyrola, radix pseudostellariae, ginseng, Rhizoma Chuanxiong, caulis bambusae in taenian, Artemisia capillaris, uncaria, rhizoma anemarrhenae, Caulis Spatholobi, Rhizoma Atractylodis Macrocephalae, osmanthus Branch, Morinda officinalis, safflower, rhizoma atractylodis, Poria cocos, Radix Ophiopogonis, Schisandra chinensis, tea root, Ramulus Taxilli are put into decocting container, add 8 times of amounts of water, leaching Bubble is after 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, by first time decoction liquor It pours into container；

2, the dregs of a decoction of filtering are added into 6 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

3, it decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.

Spina date seed nourishing the liver in prescription, calming heart are calmed the nerves, and arrest sweating, Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the work(of moisturize laxation Both energy are monarch drug in a prescription；Seed of Oriental arborvitae mental-tranquilization, relaxes bowel, and rhizoma zingiberis has middle benefit gas by cold, the function of recover Yang and smooth venation, with psoralea corylifolia, Thizoma curculiginis, Herba Cistanches, Radix Astragali, Radix Polygalae, grass-leaved sweetflag, Radix Glehniae be ministerial drug, ten simply medicine play jointly antitoxic heart-soothing and sedative, benefiting blood and regulating blood circulation, For middle benefit gas by cold, recover Yang and smooth venation, moisturize laxation effect, treatment cardiac arrhythmia effect is comprehensive, and with antitoxic heart-soothing and sedative, benefiting blood and regulating blood circulation, Middle benefit gas can effect a permanent cure by trembling with fear, based on recover Yang and smooth venation；Ginseng reinforces vital energy, prevent prolapse and engender liquid, the function of tranquilizing the mind and lily, pyrola, Radix pseudostellariae, Rhizoma Chuanxiong, caulis bambusae in taenian, Artemisia capillaris, uncaria, rhizoma anemarrhenae, Caulis Spatholobi are adjutant；Schisandra chinensis is astringed the lung, and nourshing kidney is promoted the production of body fluid, and receives sweat, puckery The function of essence is to make medicine with remaining all medicines, is to take stopgap measures.

Drug of the present invention has the function of antitoxic heart-soothing and sedative, benefiting blood and regulating blood circulation, middle benefit gas by cold, recover Yang and smooth venation, prevent prolapse and engender liquid, is used for Treat cardiac arrhythmia, short treating period, quick, non-relapse after healing.

Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.

The animal toxicity test of [test example 1] drug of the present invention is reported：

Rabbit 30, male and female dual-purpose, weight 2.0-2.5kg is taken to be divided to two groups, every group 15, one of which is overdose test group, Another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount 10ml/kg, administering mode is administration by gavage administration, Twice daily, 7 days are even served, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad poison Side effect.

The clinical observation on the therapeutic effect of [test example 2] drug of the present invention

1, general information

Accept cardiac arrhythmia out-patient totally 30 for medical treatment.

2, diagnostic criteria

Classical symptom is：Palpitaition, heartbeat be slow, irregular heartbeat, heart pause etc. between heartbeat.

3, therapy

Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 15 days as a treatment course, continuously It takes 3 course for the treatment of.

4, efficacy assessment standard

It is effective：Cardiac arrhythmia symptom disappears, and restores normal, recovery from illness；

It improves：The phenomenon that patient's palpitaition, heartbeat be slow, irregular heartbeat mitigates, and the symptoms were significantly improved for cardiac arrhythmia, gradually restores Normally；

In vain：Improvement standard person is not achieved.

5, treatment results（It see the table below）

In above-mentioned treatment, with drug therapy cardiac arrhythmia patient 30 of the present invention, as a result effective 25, obvious effective rate is 83.33%, it improves 4, improvement rate 13.33%, invalid 1, total effective rate 96.67%.

Claims (3)

1. a kind of drug for treating cardiac arrhythmia, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：

15-20 grams of spina date seed, 10-20 grams of Radix Angelicae Sinensis, 10-15 grams of the seed of Oriental arborvitae, 5-10 grams of rhizoma zingiberis, 10-15 grams of psoralea corylifolia, thizoma curculiginis 10- 20 grams, 10-20 grams of Herba Cistanches, 5-15 grams of Radix Astragali, 5-10 grams of Radix Polygalae, 5-15 grams of grass-leaved sweetflag, 10-20 grams of Radix Glehniae, lily 10-15 Gram, 10-20 grams of pyrola, 5-15 grams of radix pseudostellariae, 5-10 grams of ginseng, 5-15 grams of Rhizoma Chuanxiong, 3-9 grams of caulis bambusae in taenian, 5-10 grams of Artemisia capillaris, hook 5-15 grams of rattan, 5-10 grams of rhizoma anemarrhenae, 5-15 grams of Caulis Spatholobi, 5-10 grams of Rhizoma Atractylodis Macrocephalae, 10-20 grams of cassia twig, 10-15 grams of Morinda officinalis, safflower 5- 10 grams, 10-15 grams of rhizoma atractylodis, 10-20 grams of Poria cocos, 5-15 grams of Radix Ophiopogonis, 5-10 grams of Schisandra chinensis, 10-20 grams of tea root, Ramulus Taxilli 5-10 Gram.

2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：

18 grams of spina date seed, 15 grams of Radix Angelicae Sinensis, 12 grams of the seed of Oriental arborvitae, 8 grams of rhizoma zingiberis, 12 grams of psoralea corylifolia, 15 grams of thizoma curculiginis, 15 grams of Herba Cistanches, Huang 10 grams of stilbene, 8 grams of Radix Polygalae, 10 grams of grass-leaved sweetflag, 15 grams of Radix Glehniae, 12 grams of lily, 15 grams of pyrola, 10 grams of radix pseudostellariae, 8 grams of ginseng, 10 grams of Rhizoma Chuanxiong, 6 grams of caulis bambusae in taenian, 8 grams of Artemisia capillaris, 10 grams of uncaria, 8 grams of rhizoma anemarrhenae, 10 grams of Caulis Spatholobi, 8 grams of Rhizoma Atractylodis Macrocephalae, 15 grams of cassia twig, Morinda offcinalis How It 12 grams, 8 grams of safflower, 12 grams of rhizoma atractylodis, 15 grams of Poria cocos, 10 grams of Radix Ophiopogonis, 8 grams of Schisandra chinensis, 15 grams of tea root, 8 grams of Ramulus Taxilli.

3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：

（One）Stock

（1）Spina date seed：Active compound is put into bamboo basket, sinks in clear water cylinder, benevolence is made to keep afloat, and thorn benevolence is pulled out, shone by the heavy bottom of shell It is dry；

（2）Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit is slightly dried in the air, and slice dries；

（3）The seed of Oriental arborvitae：Net impurity is picked, remaining shell and kind skin are removed；

（4）Rhizoma zingiberis：Net impurity is picked, is soaked in water 3-6 hours, pulls out, be sliced or dice after bored profit, dry；

（5）Psoralea corylifolia：It winnows with a dustpan most impurity, cleans, dry；

（6）Thizoma curculiginis：It takes net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after moisturizing, sets micro- stir-fry in pot and take out, dry to doing；

（7）Herba Cistanches：Net impurity is picked, clear water impregnates, changes water 1-2 times a day, be such as salty desert cistanche, steeps salinity to the greatest extent, moisturizes, longitudinally cut Piece dries；

（8）Radix Astragali：Net impurity is picked, remaining head and hollow the greater is removed, is soaked in water, pulls out, is sliced in time after moisturizing, It dries；

（9）Radix Polygalae：Impurity is picked, segment weeds out grey bits；

（10）Grass-leaved sweetflag：Impurity is picked, is cleaned, is impregnated, moisturize slightly, is sliced, dries；

（11）Radix Glehniae：Impurity is picked, stem foot is removed, is slightly washed with water, pull out, slightly moisten, segment is dried；

（12）Lily：Pick impurity, black valve, ash disposal of winnowing with a dustpan bits；

（13）Pyrola：Impurity is picked, silt is weeded out, is cleaned, is slightly moistened, chop up, dry；

（14）Radix pseudostellariae：Fibrous root is extractd, is dried；

（15）Ginseng：Except removing LU, segment；

（16）Rhizoma Chuanxiong：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, and is sliced after bored profit, dry；

（17）Caulis bambusae in taenian：Hard bamboo stick, impurity are removed, grey bits are shaked off, is kneaded into small group or segment；

（18）Artemisia capillaris：Sieving picks impurity, removes undesirable root, pulverizes, spare is removed after square-bottomed bamboo basket；

（19）Uncaria：Old stalk, impurity are picked, cleans, dries；

（20）Rhizoma anemarrhenae：Net impurity is picked, is hit and is washed with water, is pulled out, is softened, slice dries；

（21）Caulis Spatholobi：Moisturized with water, be sliced, or steam it is soft after multiply fervent piece, dry；

（22）Rhizoma Atractylodis Macrocephalae：Net impurity is picked, is soaked in water, is pulled out after bubble, is moisturized, is sliced, dries；

（23）Cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；

（24）Morinda officinalis：Impurity is picked, after being soaked with hot water, pumps core while hot, segment is dried；

（25）Safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dries；

（26）Rhizoma atractylodis：Impurity is picked, thoroughly with bubble to seven, eighty per cant, pulls out, is sliced, dries after moisturizing；

（27）Poria cocos：It is soaked in water, cleans and pull out, after bored, slice dries；

（28）Radix Ophiopogonis：Net impurity is picked, is soaked in water, is pulled out, the heart is pumped after moisturizing, then clean and dry；

（29）Schisandra chinensis：Grey bits are weeded out, impurity is removed, sets in food steamer and steams thoroughly, taking-up is dried；

（30）Tea root：Crude drug is taken, impurity is removed, is cleaned, is moisturized, cut sheet, it is dry, weed out clast；

（31）Ramulus Taxilli：It is eluted with water, moisturizes, segment is dried；

（Two）It prepares

（1）By the spina date seed of the weight, Radix Angelicae Sinensis, the seed of Oriental arborvitae, rhizoma zingiberis, psoralea corylifolia, thizoma curculiginis, Herba Cistanches, Radix Astragali, Radix Polygalae, stone Chang Pu, Radix Glehniae, lily, pyrola, radix pseudostellariae, ginseng, Rhizoma Chuanxiong, caulis bambusae in taenian, Artemisia capillaris, uncaria, rhizoma anemarrhenae, Caulis Spatholobi, Rhizoma Atractylodis Macrocephalae, osmanthus Branch, Morinda officinalis, safflower, rhizoma atractylodis, Poria cocos, Radix Ophiopogonis, Schisandra chinensis, tea root, Ramulus Taxilli are put into decocting container, add 8 times of amounts of water, leaching Bubble is after 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, by first time decoction liquor It pours into container；

（2）The dregs of a decoction of filtering are added into 6 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；

（3）It decoction liquor will be mixed evenly twice, and be divided into 4 doses and take.