CN108619307A

CN108619307A - Prepared rehmannia root is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108619307A
Application number: CN201810733304.7A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-09

Abstract

The invention discloses a kind of " prepared rehmannia root is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Prepared rehmannia root harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%, contains acteoside（C₂₉H₃₆O₁₅）No less than 0.040%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.

Description

Prepared rehmannia root is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of prepared rehmannia root medicine materical crude slice.

Background technology

Chinese medicine prepared rehmannia root is glutinous rehmannia（Scrophulariaceae rehmannia glutinosa plantRehmannia glutinosaLibosch. fresh or dry Dry root tuber）Processed goods, have and enrich blood enriching yin, the effect of beneficial to spirit and marrow.For blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation collapses Leak down blood, the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, dizziness, tinnitus, and poliosis etc. is controlled It treats, is a herb common on tcm clinical practice.The processing method of traditional prepared rehmannia root is：Radix rehmanniae recen is taken, is stewed to wine according to the wine method of stewing Exhaust, take out, when drying is slightly dry to crust mucus, cut sheet or block, it is dry to get.Or radix rehmanniae recen is taken, it steams to black profit, takes out, It shines to when about most probably doing, cuts sheet or block, drying is big to get thus obtained prepared rehmannia root medicine materical crude slice volume, and Hygienic Standard is poor, easily In make moist, it is mildew, infested, be unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, it is clinical Curative effect is difficult to ensure, patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, It is imperative conducive to keeping, carrying and easy to use, rapid-action novel prepared rehmannia root medicine materical crude slice.Existing market prepared rehmannia root medicine materical crude slice, is removed Except traditional medicine materical crude slice, also Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice two kinds of forms, but be both original with traditional medicine materical crude slice Material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only carry Take out water-soluble components.

Invention content

The invention discloses a kind of " prepared rehmannia root is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：In prepared rehmannia root After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece Steam by water bath that this is cut takes out and is added in the water of 1 ~ 5 times of 100 DEG C of weight to black profit, impregnates and simultaneously constantly stirs It mixes 5 ~ 30 minutes, filters, dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is taken advantage of Heat filtering, the dregs of a decoction are squeezed the juice again, collect concoction.Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, it is concentrated into the concentrate that relative density is 1.02 ~ 1.10.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.It will The spray powder of collection and spare concentrate mixing granulation, dry to be less than 10% to water content, whole grain, vacuum packaging to get at Product.Containing acteoside（C₂₉H₃₆O₁₅）No less than 0.040%.Prepared rehmannia root granule pieces stable quality, good fluidity are clinical general Usage amount is 1 ~ 5g.Such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet, to carry significantly The high convenience and compliance of Clinical practice, is conducive to the treatment of clinical acute disease.

The present invention solve traditional prepared rehmannia root medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular Medicine materical crude slice is more preferable.

Specific embodiment

It after prepared rehmannia root medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly Water is cleaned, and is cut into the piece of 3mm thickness, Steam by water bath to black profit, is taken out.This piece is added to 100 DEG C of pure water of 5 times of weight, Stirring 30 minutes, filtering, dregs pressing take juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again boils 20 minutes Extraction, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, dense It is 1.05 to be reduced to relative density.The concentrate of gained is left and taken into 3% spare, remaining spray drying.Spray powder is collected, and it is spare Concentrate mixing pelleting, 80 DEG C be dried under vacuum to water content be 10%, whole grain, be vacuum-packed to get finished product.Containing feltwort Glucosides（C₂₉H₃₆O₁₅）No less than 0.050%.

Claims

1. a kind of prepared rehmannia root is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：After glutinous rehmannia harvests, cleans, go in time Except the impurity such as silt and dis-medicinal part, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, Steam by water bath is extremely Black profit is taken out, and the water of 1 ~ 5 times of 100 DEG C of weight is added, and impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice；Institute The water for adding 5 ~ 10 times of weight in the dregs of a decoction is obtained, boils 10 ~ 30 minutes, filters while hot, the dregs of a decoction are squeezed the juice again, collect concoction；It closes And above-mentioned concoction, 60 ~ 100 mesh sieve is crossed, is concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；Gained Concentrate leaves and takes 1% ~ 3% spare, remaining spray drying；By the spray powder of collection and spare concentrate mixing granulation, drying is extremely Water content is less than 10%, and whole grain is vacuum-packed to get finished product；Containing acteoside（C₂₉H₃₆O₁₅）No less than 0.040%.

2. prepared rehmannia root according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally makes Dosage is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.