CN108619216A

CN108619216A - Root of Chinese trichosanthes is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108619216A
Application number: CN201810733290.9A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-09

Abstract

The invention discloses a kind of " root of Chinese trichosanthes is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Root of Chinese trichosanthes harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.

Description

Root of Chinese trichosanthes is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of root of Chinese trichosanthes medicine materical crude slice.

Background technology

Trichosanthin is cucurbitaceous plant snakegourdTrichosanthes kirilowii Or trichosanthes rosthornii Harms Maxim.Trichosanthes rosthornii The effect of dry root of Harms has clearing heat-fire, promotes the production of body fluid to quench thirst, detumescence and apocenosis. This product is mainly used for pyreticosis polydipsia, lung-heat type cough, Heat Diabetes, the treatment of sore swollen toxin etc., is common one on tcm clinical practice Taste Chinese medicine.The processing method of traditional root of Chinese trichosanthes is：Autumn, the excavation of two season of winter, are cleaned, and are removed crust, segment or vertical profile into valve, are done Dry, packaging.Thus obtained root of Chinese trichosanthes medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested, being unfavorable for protecting Pipe, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure, patient takes not side Just, it works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry and it is easy to use, Rapid-action Novel ceiling powder medicine materical crude slice, it is imperative.Existing market root of Chinese trichosanthes medicine materical crude slice, other than traditional medicine materical crude slice, also ultra micro Two kinds of forms of powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality is decided by traditional medicine materical crude slice Quality, and ultramicro decoction piece cannot solve the problems, such as medicinal material pollute；Concentrated granular can only extract water-soluble components.

Invention content

The invention discloses a kind of " root of Chinese trichosanthes is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：In root of Chinese trichosanthes After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.02 ~ 1.10 concentrate.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.By the spray powder of collection with it is spare Concentrate mixing granulation, dry to be less than 10% to water content, whole grain is vacuum-packed to get finished product.Root of Chinese trichosanthes granule pieces quality Stablize, good fluidity, clinical general usage amount is 1 ~ 5g.Such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter capsule In agent and tablet, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.

The present invention solve traditional root of Chinese trichosanthes medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular Medicine materical crude slice is more preferable.

Specific embodiment

It after root of Chinese trichosanthes medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density. The concentrate of gained is left and taken into 3% spare, remaining spray drying.Spray powder is collected, pelleting is mixed with spare concentrate, It is 10% that 80 DEG C, which are dried under vacuum to water content, and whole grain is vacuum-packed to get finished product.

Claims

1. a kind of root of Chinese trichosanthes is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：After root of Chinese trichosanthes harvesting, clean in time, Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~ The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 are added in the gained dregs of a decoction The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；Gained concentrate leaves and takes 1% ~ 3% It is spare, remaining spray drying；By the spray powder of collection and spare concentrate mixing granulation, drying to water content is whole less than 10% Grain is vacuum-packed to get finished product.

2. root of Chinese trichosanthes according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally makes Dosage is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.