CN108567931A - A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis - Google Patents
A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis Download PDFInfo
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Abstract
The present invention is a kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, and the primary raw material of following weight proportions is taken to be prepared：40 50 parts of cassia twig, 30 45 parts of Poria cocos, 5 15 parts of latifolious rush rhizome, 15 25 parts of Semen Leonuri, 38 parts of safron, 12 24 parts of Rhizoma Chuanxiong, 20 30 parts of motherwort, 20 40 parts of coix seed, 13 27 parts of safflower, 4 17 parts of Radix Astragali, 10 15 parts of the fruit of glossy privet, 4 10 parts of longan, 15 25 parts of Paris polyphylla, 15 20 parts of Fructus Corni.Significant effect of the cassia twig tuckahoe compound preparation to menstrual disorder caused by adenomyosis, it is not only promoting blood circulation and removing blood stasis, it can also recuperating qi-blood, improve patient's slight illness that the menstrual disorder caused by adenomyosis is brought for a long time, and the common medicinal material in multiselect place of the present invention, it is cheap, alleviate the financial burden of patient.
Description
Technical field
The invention discloses a kind of cassia twig tuckahoe compound preparations, especially a kind of to treat menstruation mistake caused by adenomyosis
Cassia twig tuckahoe compound preparation of tune and preparation method thereof, the invention belongs to traditional Chinese medicine fields.
Background technology
Adenomyosis is endometrial gland and interstitial intrusion mesometrium formation is diffused or the lesion of limitation, with son
Endometriosis is the same, belongs to common gynecological disease and difficult disease.Adenomyosis mostly occur in 30~50 years old or so through production
Woman, but also seen in the women that youth is not given birth to, this may perform the operation to increase with various uteroventral operations certain relationship.About 15%
Patient merges endometriosis, and about 50% merges fibroid.
The cause of disease：Adenomyosis unknown etiology as yet.Current common recognition is because uterus lacks submucosa, therefore uterus
The basal layer cell hyperplasia of inner membrance, invasion arrive mesometrium, and accompany by the muscle layer compensatory cellular hyperplasia of surrounding and formed
Lesion.Chinese medicine thinks that this disease is burnt by the stagnation of the circulation of vital energy, cold solidifying, heat, the deficiency of vital energy, kidney deficiency cause stagnation of blood stasis punching to be appointed, uterus, and blockage of menstruation is then
Dysmenorrhoea.Stagnation of blood stasis punching is appointed, uterus is main pathogenesis.Uterus adenomyosis clinical manifestation adenomyosis mostly occurs in 40 years old in the past
Above multipara, but be in recent years gradual rejuvenation trend, this may increase with intrauterine surgicals such as Cesarean esction, induced abortion has
It closes.
1. symptom：（1）Menstrual disorder（40%~50%）It is mainly shown as that menostaxis, hyper-menorrhea, some patientss are also
It is likely to occur drop bleeding before and after menstruation, serious patient can lead to anaemia.（2）Dysmenorrhoea（25%）Feature is secondary progress
Property aggravate dysmenorrhoea.Often start to occur in menstrual onset the last week, alleviate when menstrual period terminate dysmenorrhoea.Dysmenorrhoea initial stage takes analgesic
Drug can be alleviated, but with disease progression, and dysmenorrhoea needs the analgesic drug product dosage taken to obviously increase, keeps patient resistance to
By.（3）Other about 35% patient's non-evident symptons.2. sign：Gynecologial examination uterus often uniformly increases spherical in shape, uterus
Adenomyoma can behave as the hard tubercle of matter.Uterus is usually no more than pregnant 12 weeks sizes.Menstrual period are closed on, uterus has tenderness to feel；Menstrual period,
Uterus increases, and quality softens, and tenderness becomes apparent from than usual；After menstrual period, uterus reduces.Uterus is often especially subsequent straight with surrounding
Intestinal adhesion and activity it is poor.15%~40% merges endometriosis, about half patient merges fibroid.
In the patent of existing treatment adenomyosis, 104997882 A of application publication number CN（Application number
201510512055.5）Chinese patent literature disclose it is a kind of for treating the Chinese medicine of adenomyosis, which is characterized in that it
It is to be prepared by the raw medicinal material of following weight proportion：15 parts of hairy raspberry herb, 9 parts of Japanese anemone root, 9 parts of Jehol Ligusticum Rhizome, sieve of chopping off the tongues
9 parts, 10 parts of Aralia continentalis.Kitagawa, 15 parts of motherwort, 10 parts of the root of Chinese clematis, 10 parts of peach kernel.104857432 A of application publication number CN
（Application number 201510245491.0）Chinese patent literature disclose a kind of Chinese medicine composition for treating adenomyosis, it is special
Sign is, is made of the Chinese medicine material of following weight：5 ~ 15 parts of the tuber of pinellia, 5 ~ 15 parts of dried orange peel, Poria cocos 10 ~ 17
Part, 10 ~ 17 parts of rhizoma cyperi, 5 ~ 15 parts of the fruit of glossy privet, 10 ~ 17 parts of curcuma zedoary, 10 ~ 17 parts of rhizoma atractylodis, 10 ~ 17 parts of root of Aucklandia lappa Decne, Radix Glycyrrhizae
5 ~ 15 parts, 20 ~ 28 parts of Radix Salviae Miltiorrhizae, 15 ~ 25 parts of Radix Angelicae Sinensis.
It can be seen that Chinese medicine plays a very important role in terms of adenomyosis, but do not have also in existing patent
There is the Chinese medicine prescription dedicated for adenomyosis.
Invention content
For the insufficient present situation of menstrual disorder caused by existing treatment adenomyosis, it is an object of the present invention to carry
For a kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, have easy to carry, function and effect are bright
Aobvious, can be quickly play the role of be promoting blood circulation and removing blood stasis, analgesic, improves menstrual disorder, and it is using in relatively conventional in the localities
Medicinal material is of low cost as raw material.
Another object of the present invention is just to provide the preparation method of above-mentioned cassia twig tuckahoe compound preparation.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, takes the main original of following weight proportions
Material is prepared：40-50 parts of cassia twig, 30-45 parts of Poria cocos, 5-15 parts of latifolious rush rhizome, 15-25 parts of Semen Leonuri, 3-8 parts of safron, river
12-24 parts of rhizome of chuanxiong, 20-30 parts of motherwort, 20-40 parts of coix seed, 13-27 parts of safflower, 4-17 parts of Radix Astragali, 10-15 parts of the fruit of glossy privet, dragon
4-10 parts of eye, 15-25 parts of Paris polyphylla, 15-20 parts of Fructus Corni.
A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, optimum ratio take following heavy
The primary raw material of amount proportioning is prepared：43-48 parts of cassia twig, 36-40 parts of Poria cocos, 8-13 parts of latifolious rush rhizome, 18-23 parts of Semen Leonuri,
4-7 parts of safron, 16-20 parts of Rhizoma Chuanxiong, 23-28 parts of motherwort, 23-28 parts of coix seed, 19-21 parts of safflower, 10-12 parts of Radix Astragali,
11-14 parts of the fruit of glossy privet, 6-8 parts of longan, 18-23 parts of Paris polyphylla, 16-19 parts of Fructus Corni.
A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, more preferably preferred proportioning, takes
The primary raw material of following weight proportioning is prepared：45 parts of cassia twig, 38 parts of Poria cocos, 10 parts of latifolious rush rhizome, 20 parts of Semen Leonuri, safron
6 parts, 18 parts of Rhizoma Chuanxiong, 25 parts of motherwort, 25 parts of coix seed, 20 parts of safflower, 11 parts of Radix Astragali, 12.5 parts of the fruit of glossy privet, 7 parts of longan, weight
20 parts of building, 17.5 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, preparation process are as follows：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
Impregnated 30-60 minutes with warm water, the dosage of warm water be latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower,
3-5 times of Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering, by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong,
Motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 2-6 minutes, dry in the air cool, grind
It is broken, it is for use to cross 80-120 mesh sieve；
（2）The shell of longan is detached with meat, adds vinegar, steeps 20-40 minutes, boiling is added to boil, after boiling 10-20 minutes, is filtered, filter
Liquid is for use；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 40-60 points of filterings, filtrate is dried in the air to room temperature
When put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 2-6 minutes with big iron spoon, are stood, are taken supernatant
For use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
Above-mentioned preparation method, step（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
Stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni are impregnated 40-50 minutes with warm water（Preferably, by latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong,
Motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni are impregnated 55 minutes with warm water）.
Above-mentioned preparation method, step（1）The dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, Job's tears
3.5-4.5 times of benevolence, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight（Preferably, the dosage of warm water is latifolious rush rhizome, motherwort
Son, safron, Rhizoma Chuanxiong, motherwort, 4 times of coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight）.
Above-mentioned preparation method, step（1）Baking 3-5 minutes, dries in the air cool, grinds, and it is for use to cross 90-110 mesh sieve（Preferably, it bakes
System 4 minutes, dries in the air cool, grinds, and sieves with 100 mesh sieve for use）.
Above-mentioned preparation method, step（2）The shell of longan is detached with meat, adds vinegar, is steeped 25-35 minutes, is added boiling to boil, wait boiling
After rising 13-18 minutes, filtering（Preferably, the shell of longan is detached with meat, adds vinegar, steeped 30 minutes, add boiling to boil, wait for boiling 15
After minute, filtering）.
Above-mentioned preparation method, step（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 45-
55 points of filterings（Preferably, cassia twig and Poria cocos are placed in marmite plus water, intense fire is fried open, turn to be cooked by slow fire 50 points of filterings）.
Above-mentioned preparation method, step（3）Big fire is decocted to boiling, is ceased fire after being stirred 3-5 minutes with big iron spoon（Preferably,
Big fire is decocted to boiling, is ceased fire after being stirred 4 minutes with big iron spoon）.
The cassia twig tuckahoe compound preparation is not only promoting blood circulation and removing blood stasis to the significant effect of menstrual disorder caused by adenomyosis,
Can also recuperating qi-blood, improve patient's slight illness that the menstrual disorder caused by adenomyosis is brought for a long time, and multiselect of the present invention use
The common medicinal material in place, it is cheap, alleviate the financial burden of patient.
A kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, the pharmacological effect of each bulk pharmaceutical chemicals
Respectively：
Cassia twig：Chinese medicine cassia twig is the dry twig of canella Chinese cassia tree, is generally harvested in spring, summer, is gone after disleaf directly
It dries or is sliced and dry.Cassia twig pungent-warm, can cold-dispelling, cold, fever with chilliness etc. can be treated.Cassia twig decoction has drop
Temperature, refrigeration function；Decoction and alcohol leaching also have inhibiting effect to staphylococcus aureus, typhoid bacillus, influenza virus etc.；It is contained
Volatile oil can stimulate sweat gland, expansion blood vessel, moreover it is possible to diuresis, cardiac stimulant, cough-relieving, eliminating the phlegm etc.；Contained cinnaldehydrum has analgesia, calmness, resists
Convulsion effect.Cassia twig modern application：Modern clinic can treat gynecological diseases such as hysteromyoma, preceding with his medicine of this product compatibility
A variety of diseases such as row adenositis, cerebral infarction, pulmonary heart disease, pernio, sciatica, allergic rhinitis.
Poria cocos：It is sweet in flavor, light, it is mild-natured.The thoughts of returning home, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema oliguria, phlegm
Drink feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Latifolious rush rhizome：It is mild-natured, acrid flavour slight bitter.Regulating qi-flowing for relieving pain, menstruation regulating and blood.Control stagnation of QI due to depression of the liver, pain in chest and hypochondrium, menstrual disorder,
Under metrorrhagia band.
Semen Leonuri：It is pungent, bitter, it is slightly cold.Channel tropism Thoughts of returning home bag, Liver Channel.Effect promoting blood circulation for regulating menstruation, clears liver and improve vision.It cures mainly and is used for menstruation
It is uncomfortable, closed dysmenorrhea, cataract, dizzy distending pain.
Safron：Its drying column cap is sweet in flavor mild-natured, can be promoting blood circulation and removing blood stasis, dissipates Yu Kaijie, analgesic.For treating troubled thoughts pent-up,
Chest diaphragm ruffian is bored, spits blood, and typhoid fever is gone mad, and shies and is afraid of in a trance, women's Amenorrhea, stasis irregular menstruation, prolonged lochia, and hemostasis is had a pain,
Measles, traumatic injury etc..Foreign countries are used as calm, carminative.It is promoting blood circulation and removing blood stasis, removing pattogenic heat from the blood and toxic material from the body, resolving stagnation for tranquilization.Febrile virulent maculae, melancholy
Ruffian is bored, palpitation with fear is gone mad.
Rhizoma Chuanxiong：Rhizoma Chuanxiong（Scientific name：Ligusticum chuanxiong hort）, cultivated plant, main product is in Sichuan（Guanxian county）,
On Yunnan, Guizhou, Guangxi and other places, it is grown on mild climatic environment.It is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-dispelling
Analgesic, Rhizoma Chuanxiong pungent-warm perfume (or spice) is dry, walks without keeping, can go it is scattered, uplink up to mountain peak push up；Enter blood system again, downlink is up to the sea of blood.Promoting blood circulation is dispelled
Stasis of blood effect is extensive, suitable for the various illnesss of stagnation of blood stasis；Wind-expelling pain-stopping, effectiveness is favourable, can control the diseases such as head wind headache, arthralgia pain due to rheumatism.
It is the gas medicine in blood that former times people, which calls Rhizoma Chuanxiong, nearly says its function such as pungent scattered, Xie Yu, sensible, analgesic of residing.
Motherwort：Motherwort, also known as：Tui, motherwort, female grass, nine Paris polyphylla, mica grass, the gloomy base of a fruit [1], Classification system：
Leonurus artemisia （Laur.）S. Y. Hu F are Labiatae, mother wort plant, summer-flowering.Its dry ground
Top is divided into conventional Chinese medicine, and most of China area is produced, and raw use or cream are used.1 year or the biennial herb whole nation are mostly
Qu Jun is distributed, and is born in hill wasteland, ridge, meadow etc..It is picked when summer riotous growth spends non-standard-sized sheet, acrid flavour is bitter, cool,
It invigorates blood circulation, silt of dispelling, menstruation regulating, disappear water, treatment menoxenia, threatened abortion difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia
Leak down, hematuria rushes down blood, carbuncle swells sore.
Coix seed：Returns spleen, stomach, lung channel.Advantageous water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, the effect of detoxicating and resolving a mass.With
In oedema, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness contraction, lung carbuncle, acute appendicitis；Wart, cancerous swelling.
Safflower：Safflower,（Classification system：Carthamus tinctorius L.）, alias：Red blue flower, thorn safflower, chrysanthemum
Section, safflower plant, dry tubular flower is orange red, and floral tube is narrow thin, and apex 5 is split, sliver narrow line shape, and anther yellow is unified into
Pipe, is higher by except sliver, there is column cap exposing in center.Have special fragrance, mildly bitter flavor.It is long with flower piece, color is scarlet, the soft person of matter is
It is good.Invigorate blood circulation, removing blood stasis and analgesics contribute to controlling through closing, dysmenorrhoea, lochia, chest impediment and cardialgia, stasis of blood, chest side of body shouting pain, fall
Beat damage, sore swell and ache curative curative effect.
Radix Astragali：Radix Astragali, Chinese medicine name.This product is the root of legume astragalus mongolicus.Spring, autumn excavation, remove soil, palpus
Root and root head shine to 6 seventy percent dry, and reason is dried after directly lashing.Major function is：Invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.
For treatment deficiency of vital energy weak, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub-official prolapses, chronic rephrilis protinuria, diabetes, the long disunion of the open sore part.
The fruit of glossy privet：Filling liver kidney, strong waist and knee.Yin asthenia generating intrinsic heat is controlled, dizzy, mesh flower, tinnitus, soreness and weakness of waist and knees, poliosis.Nourishing
Liver kidney, improving eyesight black hair.For dizziness and tinnitus, soreness and weakness of waist and knees, poliosis, mesh are secretly unknown.
Longan：For longan containing abundant glucose, sucrose and protein etc., iron-holder is also relatively high, can improve thermal energy, mend
Promote hemoglobin regeneration while filling nutrition, to achieve the effect that enrich blood.The study found that arillus longan to whole body in addition to having benefit
Benefit effect is outer, especially effective to brain cell, can enhance memory, dispelling fatigue.
Paris polyphylla：For liliaceous plant Yunnan Rhizoma Paridis or the dry rhizome of paris polyphylla.Its bitter, cold nature；It is slightly poisonous.
There is clearing heat and detoxicating a, swelling and pain relieving, the effect of cool liver is calmed the frightened, is usually used in furunculosis carbuncle swells, abscess of throat, snakebite and bugbite, the pain of injury caused by falling and tumbling,
Convulsion.
Fructus Corni：The ripe dry fruit of Fructus Corni is rare medicinal herbs cornus officinalis sieb et zucc after stoning.Fruit medicine is used as medicine, for convergence
Property hematinic and tonic；It can stomach invigorating, filling liver kidney, eliminate-poverty blood, pain in the back, nerve and the diseases such as have a weak heart.Its nature and flavor is sour and astringent, enters
Liver and kidney channel.Sour and astringent convergence plays the role of nourishing liver and kidney, reinforcing the kidney and controlling noctural emission, is suitable for the soreness and weakness of waist and knees caused by kidney deficiency and liver, passes out semen
Lingering diarrhea, dizziness and tinnitus disease.
Principle of the cassia twig tuckahoe compound preparation based on menstrual disorder caused by traditional Chinese medical herbal treatment adenomyosis of the present invention.
The Chinese medicinal material of selection has promoting blood circulation and removing blood stasis, the effect of qi-regulating in, and cheap, and long-time service will not also cause patient's
Financial burden is the drug that menstrual disorder is ideal caused by treating adenomyosis.
Specific implementation mode
With reference to embodiment and the experimental example technical solution that the present invention will be described in detail, but protection domain is not limited by this.
A kind of cassia twig tuckahoe compound preparation that treating menstrual disorder caused by adenomyosis of embodiment 1, takes following heavy
The primary raw material of amount proportioning is prepared（Every part takes 10g）：40 parts of cassia twig, 30 parts of Poria cocos, 5 parts of latifolious rush rhizome, 15 parts of Semen Leonuri, kind
3 parts of safflower, 12 parts of Rhizoma Chuanxiong, 20 parts of motherwort, 20 parts of coix seed, 13 parts of safflower, 4 parts of Radix Astragali, 10 parts of the fruit of glossy privet, 4 parts of longan, weight
15 parts of building, 15 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, step are：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
It is impregnated 30 minutes with warm water, the dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
3 times of stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering are female by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, benefit
Grass, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 2 minutes, dry in the air cool, ground, mistake
80 mesh sieve is for use；
（2）The shell of longan is detached with meat, adds vinegar, steeps 20 minutes, boiling is added to boil, waits for boiling after ten minutes, filtering, filtrate is waited for
With；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 40 points of filterings, when filtrate is dried in the air to room temperature
Put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 2 minutes with big iron spoon, are stood, are taken supernatant for use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
A kind of cassia twig tuckahoe compound preparation that treating menstrual disorder caused by adenomyosis of embodiment 2, takes following heavy
The primary raw material of amount proportioning is prepared（Every part takes 10g）：50 parts of cassia twig, 45 parts of Poria cocos, 15 parts of latifolious rush rhizome, 25 parts of Semen Leonuri,
8 parts of safron, 24 parts of Rhizoma Chuanxiong, 30 parts of motherwort, 40 parts of coix seed, 27 parts of safflower, 17 parts of Radix Astragali, 15 parts of the fruit of glossy privet, longan 10
Part, 25 parts of Paris polyphylla, 20 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, step are：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
It is impregnated 60 minutes with warm water, the dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
5 times of stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering are female by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, benefit
Grass, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 6 minutes, dry in the air cool, ground, mistake
120 mesh sieve is for use；
（2）The shell of longan is detached with meat, adds vinegar, steeps 40 minutes, boiling is added to boil, waits for boiling after twenty minutes, filtering, filtrate is waited for
With；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 60 points of filterings, when filtrate is dried in the air to room temperature
Put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 6 minutes with big iron spoon, are stood, are taken supernatant for use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
A kind of cassia twig tuckahoe compound preparation that treating menstrual disorder caused by adenomyosis of embodiment 3, takes following weight
The primary raw material of proportioning is prepared（Every part takes 10g）：43 parts of cassia twig, 36 parts of Poria cocos, 8 parts of latifolious rush rhizome, 18 parts of Semen Leonuri, sarranine
Spend 4 parts, 16 parts of Rhizoma Chuanxiong, 23 parts of motherwort, 23 parts of coix seed, 19 parts of safflower, 10 parts of Radix Astragali, 11 parts of the fruit of glossy privet, 6 parts of longan, weight
18 parts of building, 16 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, step are：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
It is impregnated 40 minutes with warm water, the dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
3.5 times of stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering, by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, benefit
Brittle Falsepimpernel Herb, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 3 minutes, dry in the air cool, ground,
It is for use to cross 90 mesh sieve；
（2）The shell of longan is detached with meat, adds vinegar, steeps 25 minutes, boiling is added to boil, after boiling 13 minutes, filtering, filtrate is waited for
With；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 45 points of filterings, when filtrate is dried in the air to room temperature
Put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 3 minutes with big iron spoon, are stood, are taken supernatant for use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
A kind of cassia twig tuckahoe compound preparation that treating menstrual disorder caused by adenomyosis of embodiment 4, takes following weight
The primary raw material of proportioning is prepared（Every part takes 10g）：48 parts of cassia twig, 40 parts of Poria cocos, 13 parts of latifolious rush rhizome, 23 parts of Semen Leonuri, kind
7 parts of safflower, 20 parts of Rhizoma Chuanxiong, 28 parts of motherwort, 28 parts of coix seed, 21 parts of safflower, 12 parts of Radix Astragali, 14 parts of the fruit of glossy privet, 8 parts of longan,
23 parts of Paris polyphylla, 19 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, step are：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
It is impregnated 50 minutes with warm water, the dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
4.5 times of stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering, by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, benefit
Brittle Falsepimpernel Herb, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 5 minutes, dry in the air cool, ground,
It is for use to cross 110 mesh sieve；
（2）The shell of longan is detached with meat, adds vinegar, steeps 35 minutes, boiling is added to boil, after boiling 18 minutes, filtering, filtrate is waited for
With；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 55 points of filterings, when filtrate is dried in the air to room temperature
Put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after five minutes with the stirring of big iron spoon, are stood, take supernatant for use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
A kind of cassia twig tuckahoe compound preparation that treating menstrual disorder caused by adenomyosis of embodiment 5, takes following weight
The primary raw material of proportioning is prepared（Every part takes 10g）：45 parts of cassia twig, 38 parts of Poria cocos, 10 parts of latifolious rush rhizome, 20 parts of Semen Leonuri, kind
6 parts of safflower, 18 parts of Rhizoma Chuanxiong, 25 parts of motherwort, 25 parts of coix seed, 20 parts of safflower, 11 parts of Radix Astragali, 12.5 parts of the fruit of glossy privet, longan 7
Part, 20 parts of Paris polyphylla, 17.5 parts of Fructus Corni.
The preparation method of above-mentioned cassia twig tuckahoe compound preparation, step are：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
It is impregnated 45 minutes with warm water, the dosage of warm water is latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Huang
4 times of stilbene, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering are female by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, benefit
Grass, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 4 minutes, dry in the air cool, ground, mistake
100 mesh sieve is for use；
（2）The shell of longan is detached with meat, adds vinegar, steeps 30 minutes, boiling is added to boil, after boiling 15 minutes, filtering, filtrate is waited for
With；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 50 points of filterings, when filtrate is dried in the air to room temperature
Put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 4 minutes with big iron spoon, are stood, are taken supernatant for use.
（4）By step（1）Gains are put in step（3）It in gained filtrate, is decocted while heating, 5 minutes to be heated
After be put into dextrin and propolis, stir, it is dry, packing to get.
Experimental example purpose is to verify this cassia twig tuckahoe compound preparation and is lost to menstruation caused by treatment adenomyosis
Whether adjust has curative effect.It is formulated within 1993 according to the Ministry of Public Health《New Chinese medicine guideline of clinical investigations》It is total for diagnosis basis
Menstrual disorder patient caused by 400 cases of Adenomysis, average age are 35 years old.Random division is administration group and control group.
Before the experiments one day, the physical condition of patient is recorded, looks over patient body symptom daily, it is ensured that administration
Group and control group situation are almost the same.Administration group uses 5 gained cassia twig tuckahoe compound preparation of this product embodiment daily, is within 5 days
One course for the treatment of takes 5g every time, warm water delivery service or takes after mixing it with water.It checks patient body situation daily, makes a record.As a result such as following table
1：
Table 1：
Efficacy analysis：Administration group（Cassia twig tuckahoe compound preparation of the present invention）Obviously subtracted using most patient sensory symptoms at 5 days
Gently, affected part is obviously felt to take a favorable turn, and patient's mood improves, and patient is almost recovered when medication 10 days, and a period of time of being discontinued has no anti-
Multiple, the state of an illness is preferably controlled, and curative effect is apparent after control group medication.Cassia twig tuckahoe compound preparation of the present invention is quick, energy
Enough achieve the purpose that alleviate patient's pain rapidly, and recurrence rate is low, is caused by one kind safely and effectively treating adenomyosis
The cassia twig tuckahoe compound preparation of menstrual disorder.
Claims (10)
1. a kind of cassia twig tuckahoe compound preparation for treating menstrual disorder caused by adenomyosis, it is characterised in that：It takes following heavy
The primary raw material of amount proportioning is prepared：40-50 parts of cassia twig, 30-45 parts of Poria cocos, 5-15 parts of latifolious rush rhizome, 15-25 parts of Semen Leonuri,
3-8 parts of safron, 12-24 parts of Rhizoma Chuanxiong, 20-30 parts of motherwort, 20-40 parts of coix seed, 13-27 parts of safflower, 4-17 parts of Radix Astragali, female
Loyal sub- 10-15 parts, 4-10 parts of longan, 15-25 parts of Paris polyphylla, 15-20 parts of Fructus Corni.
2. the cassia twig tuckahoe compound preparation of menstrual disorder, special caused by treatment adenomyosis according to claim 1
Sign is：The primary raw material of following weight proportions is taken to be prepared：43-48 parts of cassia twig, 36-40 parts of Poria cocos, 8-13 parts of latifolious rush rhizome,
18-23 parts of Semen Leonuri, 4-7 parts of safron, 16-20 parts of Rhizoma Chuanxiong, 23-28 parts of motherwort, 23-28 parts of coix seed, safflower 19-21
Part, 10-12 parts of Radix Astragali, 11-14 parts of the fruit of glossy privet, 6-8 parts of longan, 18-23 parts of Paris polyphylla, 16-19 parts of Fructus Corni.
3. the cassia twig tuckahoe compound preparation of menstrual disorder, special caused by treatment adenomyosis according to claim 1
Sign is：The primary raw material of following weight proportions is taken to be prepared：45 parts of cassia twig, 38 parts of Poria cocos, 10 parts of latifolious rush rhizome, Semen Leonuri 20
Part, 6 parts of safron, 18 parts of Rhizoma Chuanxiong, 25 parts of motherwort, 25 parts of coix seed, 20 parts of safflower, 11 parts of Radix Astragali, 12.5 parts of the fruit of glossy privet, dragon
7 parts of eye, 20 parts of Paris polyphylla, 17.5 parts of Fructus Corni.
4. the preparation method of the cassia twig tuckahoe compound preparation according to claim 1-3, it is characterised in that：Steps are as follows：
（1）By latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni
Impregnated 30-60 minutes with warm water, the dosage of warm water be latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower,
3-5 times of Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight, filtering, by soaked latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong,
Motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni chopping, are wrapped up with tinfoil, are baked 2-6 minutes, dry in the air cool, grind
It is broken, it is for use to cross 80-120 mesh sieve；
（2）The shell of longan is detached with meat, adds vinegar, steeps 20-40 minutes, boiling is added to boil, after boiling 10-20 minutes, is filtered, filter
Liquid is for use；
（3）Cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open, turns to be cooked by slow fire 40-60 points of filterings, filtrate is dried in the air to room temperature
When put into step（2）Gained filtrate, big fire are decocted to boiling, are ceased fire after being stirred 2-6 minutes with big iron spoon, are stood, are taken supernatant
For use；
（4）By step（1）Gains are put in step（3）In gained filtrate, decocted while heating, it is to be heated to put after five minutes
Enter dextrin and propolis, stir, it is dry, packing to get.
5. preparation method according to claim 1, it is characterised in that：Step（1）By latifolious rush rhizome, Semen Leonuri, safron, river
Rhizome of chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni are impregnated 40-50 minutes with warm water（It preferably, will be careless
Rhizoma cyperi, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni are impregnated with warm water
55 minutes）.
6. preparation method according to claim 1, it is characterised in that：Step（1）The dosage of warm water is latifolious rush rhizome, motherwort
Son, safron, Rhizoma Chuanxiong, motherwort, 3.5-4.5 times of coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla, Fructus Corni weight（It is preferred that
, the dosage of warm water be latifolious rush rhizome, Semen Leonuri, safron, Rhizoma Chuanxiong, motherwort, coix seed, safflower, Radix Astragali, the fruit of glossy privet, Paris polyphylla,
4 times of Fructus Corni weight）.
7. preparation method according to claim 1, it is characterised in that：Step（1）Baking 3-5 minutes, dries in the air cool, grinds, mistake
90-110 mesh sieve is for use（Preferably, it is baked 4 minutes, dries in the air cool, grind, sieve with 100 mesh sieve for use）.
8. preparation method according to claim 1, it is characterised in that：Step（2）The shell of longan is detached with meat, adds vinegar,
Bubble 25-35 minutes, adds boiling to boil, after boiling 13-18 minutes, filtering（Preferably, the shell of longan is detached with meat, adds vinegar, steeped
30 minutes, boiling is added to boil, after boiling 15 minutes, filtering）.
9. preparation method according to claim 1, it is characterised in that：Step（3）Cassia twig and Poria cocos are placed in marmite and added
Water, intense fire are fried open, and turn to be cooked by slow fire 45-55 points of filterings（Preferably, cassia twig and Poria cocos are placed in marmite plus water, intense fire are fried open,
Turn to be cooked by slow fire 50 points of filterings）.
10. preparation method according to claim 1, it is characterised in that：Step（3）Big fire is decocted to boiling, with big iron spoon
Stirring is ceased fire after 3-5 minutes（Preferably, big fire is decocted to boiling, is ceased fire after being stirred 4 minutes with big iron spoon）.
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|---|---|---|---|---|
| CN111568989A (en) * | 2020-07-09 | 2020-08-25 | 山东中医药大学附属医院 | Application of cassia twig and rhizoma paridis dragon's blood extract in preparation of medicine for treating adenomyosis |
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| CN104606605A (en) * | 2015-03-06 | 2015-05-13 | 宋辉 | Traditional Chinese medicine composition for treating breast hyperplasia and preparation method for traditional Chinese medicine composition |
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| CN111568989A (en) * | 2020-07-09 | 2020-08-25 | 山东中医药大学附属医院 | Application of cassia twig and rhizoma paridis dragon's blood extract in preparation of medicine for treating adenomyosis |
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