CN108542834A - A kind of production method of skin whitening, moisturizing face cream - Google Patents
A kind of production method of skin whitening, moisturizing face cream Download PDFInfo
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- CN108542834A CN108542834A CN201810765210.8A CN201810765210A CN108542834A CN 108542834 A CN108542834 A CN 108542834A CN 201810765210 A CN201810765210 A CN 201810765210A CN 108542834 A CN108542834 A CN 108542834A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention belongs to cosmetic fields, and in particular to a kind of production method of skin whitening, moisturizing face cream.Olive oil, Seabuckthorn Oil, hazelnut oil, wheat embryo emulsification wax, beeswax, methyl p-hydroxybenzoate are mixed by formula rate, it is heated to 70 75 DEG C, stirring obtains mixture first until material all melts under the conditions of 70 75 DEG C, deionized water, glycerine and concentration filtrate are mixed by formula rate, it is heated to 70 75 DEG C, mixture second is obtained after stirring evenly, mixture second is added in mixture first, 50 55 minutes postcoolings are stirred under conditions of 70 75 DEG C, 150 200rpm of mixing speed and are got product to 40 DEG C or less.The face cream of the present invention has skin whitening, moisturizing effect outstanding rich in ingredients such as olive oil, Seabuckthorn Oil, hazelnut oil, ox selenium polysaccharide, dihydrophytoceramide, sodium lactates.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of production method of skin whitening, moisturizing face cream.
Background technology
There is a variety of active metallic ions, ultraviolet light, environmental pollution, operating pressure or life stress in human skin
Etc. factors can all activate these natural metal ions, will produce tyrosinase under their stimulation, and tyrosinase is stimulation
The assailant that melanin is formed in cell, under the action of tyrosinase, tyrosine is gradually oxidized to DOPA, DOPA quinone, then
It rearranges and polymerize, be finally combined into melanoprotein with protein, make skin darkening.Whitening product is cannot to eliminate
The melanin of formation, only melanin production is inhibited no longer to generate melanin, then relies on the metabolic mistake of skin itself
The melanin generated is excreted and is only safest method for whitening by journey.
Currently marketed whitening cream emerges one after another, and dives during product quality is also irregular or even certain whitening cream
Harmful substance is hidden, not only there is direct irritation to skin, it is also possible to lead to skin sensitivity, pigmentation, develop safety
Effective novel whitening face cream be the target that those skilled in the art pursue and whitening cream now and the side of future development
To.
Invention content
The object of the present invention is to provide a kind of production methods of safely and effectively novel whitening moisturizing face cream.
The object of the present invention is achieved like this：
The root of bidentate achyranthes is crushed into obtain root of bidentate achyranthes powder, according to mass ratio 2:1 ratio mixes root of bidentate achyranthes powder and food-grade defatted wheat germ powder
Uniform to obtain mixed powder, the clear water that 10-12 times of quality is added in mixed powder stirs evenly to obtain mixed serum, by every gram of mixed powder 8-
Alpha-amylase is added in the ratio of 10 units, adds the food-grade calcium chloride of mixed powder quality 0.2%, stirs evenly, in 90-
58-62 DEG C is cooled to after being digested 20-25 minutes under the conditions of 95 DEG C, lactic acid is added, pH is adjusted to 4.5-5.0, by every gram of mixed powder
Carbohydrase is added in the ratio of 60-80 unit, is saccharified 4-6 hours under the conditions of 58-62 DEG C, then cool to 45-50 DEG C, by every gram
Acid protease is added in the ratio of 15-20 unit of mixed powder, and cellulose is added in the ratio of 20-30 unit of every gram of mixed powder
Enzyme digests 1-2 hours under the conditions of 45-50 DEG C, after enzymolysis, by enzymolysis liquid moist heat sterilization 15-20 points under the conditions of 121 DEG C
Clock, is then cooled to 36-38 DEG C and obtains lactobacillus-fermented culture medium, and 0.01% Bulgaria is accessed in lactobacillus-fermented culture medium
Lactobacillus freeze-dried powder, ferment 30-35 hours to obtain streptococcus acidi lactici fermented solution under the conditions of 36-38 DEG C, by streptococcus acidi lactici fermented solution at 121 DEG C
Under the conditions of moist heat sterilization 15-20 minutes, then through cooling, filter to get filtrate, filtrate pH is adjusted with 10% sodium hydroxide solution
Filtrate must be concentrated by being concentrated to 15-20 ° of Bx after to 5.8-6.2 again.
The face cream of the present invention is formulated by several raw materials such as concentration filtrates obtained, specific constituent and quality hundred
Divide ratio as follows：
Title mass percent
Olive oil 9-13%
Seabuckthorn Oil 2-3%
Hazelnut oil 1-2%
Wheat embryo emulsifies wax 5-6%
Beeswax 1-2%
Concentrate filtrate 10-15%
Deionized water 50-60%
Glycerine 10-12%
Methyl p-hydroxybenzoate 0.10-0.14%
Olive oil, Seabuckthorn Oil, hazelnut oil, wheat embryo emulsification wax, beeswax, methyl p-hydroxybenzoate are mixed by formula rate
Together, it is heated to 70-75 DEG C, mixture first is obtained until stirring to material all thawing under the conditions of 70-75 DEG C.
Deionized water, glycerine and concentration filtrate are mixed by formula rate, 70-75 DEG C is heated to, stirs evenly
Mixture second is obtained afterwards.
Mixture second is added in mixture first, is stirred under conditions of 70-75 DEG C, mixing speed 150-200rpm
Postcooling is got product to 40 DEG C or less within 50-55 minutes.
The present invention has used two kinds of raw materials of the root of bidentate achyranthes and defatted wheat germ powder, and to this when making concentration filtrate
Two kinds of raw materials have carried out enzymolysis processing, are rich in ox selenium polysaccharide in the root of bidentate achyranthes, Inokopolyose is a kind of levulan, relative molecular mass
Small, good water solubility is easily absorbed by human body cell, and the root of bidentate achyranthes can make the root of bidentate achyranthes being present in root of bidentate achyranthes plant cell by enzymolysis
Polysaccharide is preferably discharged, and after measured, in the concentration filtrate with the method for the present invention preparation, Inokopolyose content is every hundred milliliters
1.0-1.2 gram.Rich in the dihydrophytoceramide with whitening and moisture-keeping efficacy in wheat germ powder, wheat germ powder is by enzymolysis
Effect can be such that the dihydrophytoceramide being present in wheat embryo plant cell is preferably discharged, and after measured, be sent out with this
In concentration filtrate prepared by bright method, dihydrophytoceramide content is every hundred milliliters 1.2-1.3 milligrams.Lactic acid prepared by the present invention
Fermented liquid is rich in lactic acid, and when adjusting pH with sodium hydroxide, lactic acid is generated to have and be protected with sodium hydroxide generation neutralization reaction
The sodium lactate of wet effect, after measured, in the concentration filtrate with the method for the present invention preparation, lactic acid sodium content is every hundred milliliters of 2.6-
2.8 gram.
The skin whitening, moisturizing face cream of the present invention is rich in olive oil, Seabuckthorn Oil, hazelnut oil, ox selenium polysaccharide, dihydrophytoceramide, breast
The ingredients such as sour sodium, olive oil have ultraviolet light special absorbability, skin darkening caused by burning sun being prevented to be exposed to the sun；It is husky
Serotonin and catechol have the function of anti-intense radiation in spine oil, can prevent injury of the solar ultraviolet to skin, inhibit
The activity of dead drunk propylhomoserin enzyme, prevents the generation of melanin；Hazelnut oil can filter the ultraviolet light in sunlight, inhibit the formation of melanin；
Inokopolyose can absorb the ultraviolet radiation of multiple wave bands, prevent skin darkening；Glutathione in wheat embryo can prevent
Skin aging and pigmentation, reduce the generation of melanin, and the dihydrophytoceramide in wheat embryo is had been found at present as peace
Best one of the efficient moisture-retention agent of full property highest, absorptivity, it is close with the lipid structure of human body itself, can rapidly permeate into skin
And combined with cuticula moisture, to form water lock network, while dihydrophytoceramide can also influence cell growth, differentiation, old
Change and apoptotic process, it can control melanocyte growth and form melanin function, have good white-skinned face function；Sodium lactate
It is natural moisturizing factor, the ingredient of a quarter is sodium lactate in the keratoderma of people, and the sodium lactate in face cream can prevent face
Portion's moisture of skin volatilization, makes skin be in light moisture state.So face cream of the invention is rich in olive oil, Seabuckthorn Oil, filbert
The ingredients such as oil, ox selenium polysaccharide, dihydrophytoceramide, sodium lactate have skin whitening, moisturizing effect outstanding.
Specific implementation mode
The root of bidentate achyranthes is crushed into obtain root of bidentate achyranthes powder, according to mass ratio 2:1 ratio is by root of bidentate achyranthes powder and food-grade defatted wheat germ powder
It is uniformly mixed to obtain mixed powder, the clear water that 11 times of quality are added in mixed powder stirs evenly to obtain mixed serum, by every gram of mixed powder 9
Alpha-amylase is added in the ratio of a unit, adds the food-grade calcium chloride of mixed powder quality 0.2%, stirs evenly, in 90 DEG C of items
60 DEG C are cooled to after being digested 25 minutes under part, lactic acid are added, pH is adjusted to 4.7, add in the ratio of 70 units of every gram of mixed powder
Enter carbohydrase, be saccharified 5 hours under the conditions of 60 DEG C, then cool to 47 DEG C, acid is added in the ratio of 18 units of every gram of mixed powder
Property protease, in 25 units of every gram of mixed powder ratio be added cellulase digest 1.5 hours under the conditions of 47 DEG C, enzymolysis tie
Shu Hou, by enzymolysis liquid under the conditions of 121 DEG C moist heat sterilization 15 minutes, be then cooled to 37 DEG C lactobacillus-fermented culture medium,
0.01% lactobacillus bulgaricus freeze-dried powder is accessed in lactobacillus-fermented culture medium, ferment 32 hours to obtain lactic acid under the conditions of 37 DEG C
Fermented liquid, by streptococcus acidi lactici fermented solution under the conditions of 121 DEG C moist heat sterilization 15 minutes, then through cooling, filter to get filtrate, use
10% sodium hydroxide solution is concentrated to 16 ° of Bx again after filtrate pH is adjusted to 6.0 must concentrate filtrate.
Weigh 11 kg of olive oil, 2.5 kg of Seabuckthorn Oil, 1.5 kg of hazelnut oil, 5.5 kg of wheat embryo emulsification wax, beeswax
1.5 kg, 0.1 kg of methyl p-hydroxybenzoate, mix, are heated to 75 DEG C, and stirring is complete to material under the conditions of 75 DEG C
Portion obtains mixture first until melting.
55 kg of deionized water, 10.4 kg of glycerine and concentration 12.5 kg of filtrate are mixed by formula rate, heated
To 75 DEG C, mixture second is obtained after stirring evenly.
Mixture second is added in mixture first, after being stirred 50 minutes under conditions of 75 DEG C, mixing speed 180rpm
40 DEG C or less are cooled to get product.
Using effect is tested：
Using effect test is carried out to the skin whitening, moisturizing face cream of the present invention, test event includes whitening effect, moistening effect two,
Effect assessment is carried out using scoring mechanism, full marks are 5 points, and wherein effect is very well 4.5-5.0 points, preferably 4.0-4.4 points of effect,
Effect is generally 3.0-3.9 points, and effect difference is 0-2.9 points.The experimenter totally 50 people is divided into 2 groups, every group of 25 people, wherein 25 people apply
The skin whitening, moisturizing face cream of the embodiment of the present invention is smeared, remaining 25 people smears a commercially available skin whitening, moisturizing face cream, and face cream uses 2 daily
Secondary, morning, evening are each primary, are used continuously 60 days, marking table is filled in after use, each group average mark is taken, the results are shown in Table 1：
Table 1：Face cream using effect test marking table
| Test event | Whitening effect | Moistening effect |
| Face cream of the present invention | 4.6 | 4.5 |
| Commercially available face cream | 4.0 | 4.1 |
From the point of view of the result of experimenter's self-appraisal, face cream of the invention has preferable effect in terms of whitening and moisturizing.
Claims (3)
1. a kind of production method of skin whitening, moisturizing face cream, it is characterized in that：By olive oil, Seabuckthorn Oil, hazelnut oil, wheat embryo emulsification
Wax, beeswax, methyl p-hydroxybenzoate are mixed by formula rate, are heated to 70-75 DEG C, are stirred under the conditions of 70-75 DEG C
Mixture first is mixed until material all melts to obtain, deionized water, glycerine and concentration filtrate are mixed by formula rate,
It is heated to 70-75 DEG C, mixture second is obtained after stirring evenly, mixture second is added in mixture first, in 70-75 DEG C, stirring
50-55 minutes postcoolings are stirred under conditions of speed 150-200rpm to get product to 40 DEG C or less.
2. a kind of production method of skin whitening, moisturizing face cream according to claim 1, which is characterized in that each formula group
Point mass percent be：Olive oil 9-13%, Seabuckthorn Oil 2-3%, hazelnut oil 1-2%, wheat embryo emulsification wax 5-6%, beeswax 1-
2%, concentration filtrate 10-15%, deionized water 50-60%, glycerine 10-12%, methyl p-hydroxybenzoate 0.10-0.14%.
3. a kind of production method of skin whitening, moisturizing face cream according to claim 1 or 2, which is characterized in that the concentration
Filtrate is to be prepared by the following method：The root of bidentate achyranthes is crushed into obtain root of bidentate achyranthes powder, according to mass ratio 2:1 ratio is by root of bidentate achyranthes powder and food
Grade defatted wheat germ powder is uniformly mixed to obtain mixed powder, and the clear water that 10-12 times of quality is added in mixed powder stirs evenly
Mixed serum is added alpha-amylase in the ratio of 8-10 unit of every gram of mixed powder, adds the food of mixed powder quality 0.2%
Grade calcium chloride, stirs evenly, and 58-62 DEG C is cooled to after being digested 20-25 minutes under the conditions of 90-95 DEG C, and lactic acid is added by pH tune
It is whole to arrive 4.5-5.0, carbohydrase is added in the ratio of 60-80 unit of every gram of mixed powder, the 4-6 that is saccharified under the conditions of 58-62 DEG C is small
When, then 45-50 DEG C is cooled to, acid protease is added in the ratio of 15-20 unit of every gram of mixed powder, by every gram of mixed powder
The ratio of 20-30 unit is added cellulase and is digested 1-2 hours under the conditions of 45-50 DEG C, and after enzymolysis, enzymolysis liquid is existed
Moist heat sterilization 15-20 minutes under the conditions of 121 DEG C, then it is cooled to 36-38 DEG C and obtains lactobacillus-fermented culture medium, in lactobacillus-fermented
0.01% lactobacillus bulgaricus freeze-dried powder is accessed in culture medium, ferment 30-35 hours to obtain lactic acid bacteria hair under the conditions of 36-38 DEG C
Zymotic fluid, by streptococcus acidi lactici fermented solution under the conditions of 121 DEG C moist heat sterilization 15-20 minutes, then through cooling, filter to get filtrate, with 10%
Sodium hydroxide solution be adjusted to the filtrate pH to be concentrated to 15-20 ° of Bx after 5.8-6.2 again and must concentrate filtrate.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810765210.8A CN108542834A (en) | 2018-07-12 | 2018-07-12 | A kind of production method of skin whitening, moisturizing face cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810765210.8A CN108542834A (en) | 2018-07-12 | 2018-07-12 | A kind of production method of skin whitening, moisturizing face cream |
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| CN108542834A true CN108542834A (en) | 2018-09-18 |
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| CN201810765210.8A Pending CN108542834A (en) | 2018-07-12 | 2018-07-12 | A kind of production method of skin whitening, moisturizing face cream |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366373A (en) * | 2011-11-04 | 2012-03-07 | 抚松参美化妆品有限公司 | Preparation method of ginseng fermenting extractive with enhanced whitening function |
| CN108042404A (en) * | 2018-02-08 | 2018-05-18 | 合肥工业大学 | A kind of children's face cream containing peony seed oil and preparation method thereof |
-
2018
- 2018-07-12 CN CN201810765210.8A patent/CN108542834A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366373A (en) * | 2011-11-04 | 2012-03-07 | 抚松参美化妆品有限公司 | Preparation method of ginseng fermenting extractive with enhanced whitening function |
| CN108042404A (en) * | 2018-02-08 | 2018-05-18 | 合肥工业大学 | A kind of children's face cream containing peony seed oil and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 夏征农: "《大辞海 化工轻工纺织卷》", 31 August 2009, 上海辞书出版社 * |
| 祝钧: "《化妆品植物学》", 31 July 2009, 中国农业大学出版社 * |
| 谷旭晗: "纤维素酶法提取川牛膝多糖", 《生物加工过程》 * |
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