CN108524498A - 药物组合物 - Google Patents
药物组合物 Download PDFInfo
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- CN108524498A CN108524498A CN201810706944.9A CN201810706944A CN108524498A CN 108524498 A CN108524498 A CN 108524498A CN 201810706944 A CN201810706944 A CN 201810706944A CN 108524498 A CN108524498 A CN 108524498A
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- pharmacologically active
- active ingredient
- dosage form
- pharmaceutical dosage
- pain
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Classifications
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
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- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
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- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003897.1 | 2012-05-18 | ||
| EP12003897 | 2012-05-18 | ||
| CN201380025683.XA CN104302282A (zh) | 2012-05-18 | 2013-05-16 | 包含(1r,4r)-6’-氟-N,N-二甲基-4-苯基-4’,9’-二氢-3’H-螺[环己烷-1,1’-吡喃并-[3,4,b]吲哚]-4-胺和对乙酰氨基酚或丙帕他莫的药物组合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380025683.XA Division CN104302282A (zh) | 2012-05-18 | 2013-05-16 | 包含(1r,4r)-6’-氟-N,N-二甲基-4-苯基-4’,9’-二氢-3’H-螺[环己烷-1,1’-吡喃并-[3,4,b]吲哚]-4-胺和对乙酰氨基酚或丙帕他莫的药物组合物 |
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| CN108524498A true CN108524498A (zh) | 2018-09-14 |
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| CN201810706944.9A Pending CN108524498A (zh) | 2012-05-18 | 2013-05-16 | 药物组合物 |
| CN201380025683.XA Pending CN104302282A (zh) | 2012-05-18 | 2013-05-16 | 包含(1r,4r)-6’-氟-N,N-二甲基-4-苯基-4’,9’-二氢-3’H-螺[环己烷-1,1’-吡喃并-[3,4,b]吲哚]-4-胺和对乙酰氨基酚或丙帕他莫的药物组合物 |
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| CN201380025683.XA Pending CN104302282A (zh) | 2012-05-18 | 2013-05-16 | 包含(1r,4r)-6’-氟-N,N-二甲基-4-苯基-4’,9’-二氢-3’H-螺[环己烷-1,1’-吡喃并-[3,4,b]吲哚]-4-胺和对乙酰氨基酚或丙帕他莫的药物组合物 |
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| US (3) | US20130310435A1 (https=) |
| EP (1) | EP2849740B1 (https=) |
| JP (1) | JP6116676B2 (https=) |
| CN (2) | CN108524498A (https=) |
| AU (1) | AU2013262075B2 (https=) |
| BR (1) | BR112014028561A2 (https=) |
| CA (1) | CA2873644A1 (https=) |
| CY (1) | CY1119610T1 (https=) |
| DK (1) | DK2849740T3 (https=) |
| EA (1) | EA026949B1 (https=) |
| ES (1) | ES2650441T3 (https=) |
| HR (1) | HRP20171438T1 (https=) |
| HU (1) | HUE034676T2 (https=) |
| IL (1) | IL235651B (https=) |
| LT (1) | LT2849740T (https=) |
| MX (1) | MX352596B (https=) |
| NO (1) | NO2849740T3 (https=) |
| PL (1) | PL2849740T3 (https=) |
| PT (1) | PT2849740T (https=) |
| RS (1) | RS56617B1 (https=) |
| SI (1) | SI2849740T1 (https=) |
| WO (1) | WO2013170969A1 (https=) |
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| JP6673924B2 (ja) | 2015-01-23 | 2020-03-25 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 肝機能障害および／または腎機能障害を有する対象における疼痛を治療するためのセブラノパドール |
| JP7373904B2 (ja) | 2016-02-29 | 2023-11-06 | パーク・セラピューティクス・インコーポレイテッド | セブラノパドールの滴定 |
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-
2013
- 2013-05-13 US US13/892,969 patent/US20130310435A1/en not_active Abandoned
- 2013-05-16 CA CA2873644A patent/CA2873644A1/en not_active Abandoned
- 2013-05-16 HR HRP20171438TT patent/HRP20171438T1/hr unknown
- 2013-05-16 WO PCT/EP2013/001468 patent/WO2013170969A1/en not_active Ceased
- 2013-05-16 PT PT137236741T patent/PT2849740T/pt unknown
- 2013-05-16 LT LTEP13723674.1T patent/LT2849740T/lt unknown
- 2013-05-16 NO NO13723674A patent/NO2849740T3/no unknown
- 2013-05-16 SI SI201330870T patent/SI2849740T1/en unknown
- 2013-05-16 BR BR112014028561A patent/BR112014028561A2/pt not_active IP Right Cessation
- 2013-05-16 DK DK13723674.1T patent/DK2849740T3/da active
- 2013-05-16 JP JP2015511955A patent/JP6116676B2/ja active Active
- 2013-05-16 CN CN201810706944.9A patent/CN108524498A/zh active Pending
- 2013-05-16 RS RS20171229A patent/RS56617B1/sr unknown
- 2013-05-16 AU AU2013262075A patent/AU2013262075B2/en not_active Ceased
- 2013-05-16 CN CN201380025683.XA patent/CN104302282A/zh active Pending
- 2013-05-16 ES ES13723674.1T patent/ES2650441T3/es active Active
- 2013-05-16 PL PL13723674T patent/PL2849740T3/pl unknown
- 2013-05-16 EP EP13723674.1A patent/EP2849740B1/en not_active Not-in-force
- 2013-05-16 HU HUE13723674A patent/HUE034676T2/hu unknown
- 2013-05-16 MX MX2014012723A patent/MX352596B/es active IP Right Grant
- 2013-05-16 EA EA201401272A patent/EA026949B1/ru not_active IP Right Cessation
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2014
- 2014-11-12 IL IL235651A patent/IL235651B/en active IP Right Grant
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2017
- 2017-10-06 US US15/726,761 patent/US20180092867A1/en not_active Abandoned
- 2017-11-20 CY CY20171101212T patent/CY1119610T1/el unknown
-
2019
- 2019-07-03 US US16/502,651 patent/US11311504B2/en active Active
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| CN1735619A (zh) * | 2002-11-11 | 2006-02-15 | 格吕伦塔尔有限公司 | 螺环环己烷衍生物 |
| CN101147735A (zh) * | 2006-09-19 | 2008-03-26 | 沈阳华泰药物研究有限公司 | 注射用药物组合物及其药盒 |
| US20080125475A1 (en) * | 2006-09-29 | 2008-05-29 | Grunenthal Gmbh | Mixed ORL1/mu-agonists for the treatment of pain |
Also Published As
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|---|---|
| IL235651B (en) | 2018-08-30 |
| SI2849740T1 (en) | 2018-01-31 |
| HRP20171438T1 (hr) | 2017-11-03 |
| CA2873644A1 (en) | 2013-11-21 |
| RS56617B1 (sr) | 2018-02-28 |
| AU2013262075A1 (en) | 2015-01-22 |
| NO2849740T3 (https=) | 2018-02-10 |
| HUE034676T2 (hu) | 2018-02-28 |
| DK2849740T3 (da) | 2017-11-20 |
| JP2015516449A (ja) | 2015-06-11 |
| PT2849740T (pt) | 2017-12-13 |
| HK1204940A1 (en) | 2015-12-11 |
| CN104302282A (zh) | 2015-01-21 |
| US20130310435A1 (en) | 2013-11-21 |
| EP2849740B1 (en) | 2017-09-13 |
| ES2650441T3 (es) | 2018-01-18 |
| US20180092867A1 (en) | 2018-04-05 |
| EP2849740A1 (en) | 2015-03-25 |
| BR112014028561A2 (pt) | 2017-07-25 |
| IL235651A0 (en) | 2015-01-29 |
| MX352596B (es) | 2017-11-30 |
| PL2849740T3 (pl) | 2018-03-30 |
| MX2014012723A (es) | 2015-01-15 |
| JP6116676B2 (ja) | 2017-04-19 |
| AU2013262075B2 (en) | 2017-10-26 |
| WO2013170969A1 (en) | 2013-11-21 |
| LT2849740T (lt) | 2017-12-27 |
| EA026949B1 (ru) | 2017-06-30 |
| US20190350884A1 (en) | 2019-11-21 |
| EA201401272A1 (ru) | 2015-05-29 |
| US11311504B2 (en) | 2022-04-26 |
| CY1119610T1 (el) | 2018-04-04 |
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