LT2849740T - Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano`[3,4,b]indol]-4-aminą ir paracetamolį arba propacetamolį - Google Patents

Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano`[3,4,b]indol]-4-aminą ir paracetamolį arba propacetamolį

Info

Publication number
LT2849740T
LT2849740T LTEP13723674.1T LT13723674T LT2849740T LT 2849740 T LT2849740 T LT 2849740T LT 13723674 T LT13723674 T LT 13723674T LT 2849740 T LT2849740 T LT 2849740T
Authority
LT
Lithuania
Prior art keywords
propacetamol
pyrano
paracetamol
indol
spiro
Prior art date
Application number
LTEP13723674.1T
Other languages
English (en)
Lithuanian (lt)
Inventor
Stefanie Frosch
Klaus Linz
Klaus Schiene
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of LT2849740T publication Critical patent/LT2849740T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
LTEP13723674.1T 2012-05-18 2013-05-16 Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano`[3,4,b]indol]-4-aminą ir paracetamolį arba propacetamolį LT2849740T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12003897 2012-05-18
PCT/EP2013/001468 WO2013170969A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano'[3,4,b]indol]-4-amine and paracetamol or propacetamol

Publications (1)

Publication Number Publication Date
LT2849740T true LT2849740T (lt) 2017-12-27

Family

ID=48468208

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13723674.1T LT2849740T (lt) 2012-05-18 2013-05-16 Farmacinė kompozicija, apimanti (1r,4r)-6`-fluor-n,n-dimetil-4-fenil-4`,9`-dihidro-3`h-spiro[cikloheksan-1,1`-pirano`[3,4,b]indol]-4-aminą ir paracetamolį arba propacetamolį

Country Status (22)

Country Link
US (3) US20130310435A1 (https=)
EP (1) EP2849740B1 (https=)
JP (1) JP6116676B2 (https=)
CN (2) CN108524498A (https=)
AU (1) AU2013262075B2 (https=)
BR (1) BR112014028561A2 (https=)
CA (1) CA2873644A1 (https=)
CY (1) CY1119610T1 (https=)
DK (1) DK2849740T3 (https=)
EA (1) EA026949B1 (https=)
ES (1) ES2650441T3 (https=)
HR (1) HRP20171438T1 (https=)
HU (1) HUE034676T2 (https=)
IL (1) IL235651B (https=)
LT (1) LT2849740T (https=)
MX (1) MX352596B (https=)
NO (1) NO2849740T3 (https=)
PL (1) PL2849740T3 (https=)
PT (1) PT2849740T (https=)
RS (1) RS56617B1 (https=)
SI (1) SI2849740T1 (https=)
WO (1) WO2013170969A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6673924B2 (ja) 2015-01-23 2020-03-25 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 肝機能障害および／または腎機能障害を有する対象における疼痛を治療するためのセブラノパドール
JP7373904B2 (ja) 2016-02-29 2023-11-06 パーク・セラピューティクス・インコーポレイテッド セブラノパドールの滴定

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Also Published As

Publication number Publication date
IL235651B (en) 2018-08-30
SI2849740T1 (en) 2018-01-31
HRP20171438T1 (hr) 2017-11-03
CA2873644A1 (en) 2013-11-21
RS56617B1 (sr) 2018-02-28
AU2013262075A1 (en) 2015-01-22
NO2849740T3 (https=) 2018-02-10
HUE034676T2 (hu) 2018-02-28
CN108524498A (zh) 2018-09-14
DK2849740T3 (da) 2017-11-20
JP2015516449A (ja) 2015-06-11
PT2849740T (pt) 2017-12-13
HK1204940A1 (en) 2015-12-11
CN104302282A (zh) 2015-01-21
US20130310435A1 (en) 2013-11-21
EP2849740B1 (en) 2017-09-13
ES2650441T3 (es) 2018-01-18
US20180092867A1 (en) 2018-04-05
EP2849740A1 (en) 2015-03-25
BR112014028561A2 (pt) 2017-07-25
IL235651A0 (en) 2015-01-29
MX352596B (es) 2017-11-30
PL2849740T3 (pl) 2018-03-30
MX2014012723A (es) 2015-01-15
JP6116676B2 (ja) 2017-04-19
AU2013262075B2 (en) 2017-10-26
WO2013170969A1 (en) 2013-11-21
EA026949B1 (ru) 2017-06-30
US20190350884A1 (en) 2019-11-21
EA201401272A1 (ru) 2015-05-29
US11311504B2 (en) 2022-04-26
CY1119610T1 (el) 2018-04-04

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